K. Dane Wittrup
Affiliations: | 1989-1999 | Chemical Engineering | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
| 1999- | Chemical Engineering and Biological Engineering | Massachusetts Institute of Technology, Cambridge, MA, United States |
Website:
https://be.mit.edu/directory/k-dane-wittrupGoogle:
"Karl Dane Wittrup"Bio:
http://kdw-lab.mit.edu/
http://resolver.caltech.edu/CaltechETD:etd-02212007-131607
Mean distance: 10.21 | S | N | B | C | P |
Parents
Sign in to add mentor| James E. Bailey | grad student | 1989 | Caltech | |
| (Plasmid propagation in the yeast Saccaromyces cerevisiae : flow cytometry studies and segregated modeling) | ||||
Children
Sign in to add trainee| Camille Z. McAvoy | research assistant | 2012 | MIT |
| Anne Skaja Robinson | grad student | (E-Tree) | |
| Eric V. Shusta | grad student | 1999 | UIUC (Microtree) |
| Sarah J. Bannister | grad student | 2000 | UIUC |
| Balaji M. Rao | grad student | 1999-2004 | MIT (E-Tree) |
| Greg Thurber | grad student | 2008 | MIT |
| Ben Hackel | grad student | 2009 | MIT (Imaging Tree) |
| Jamie B. Spangler | grad student | 2011 | MIT |
| Jennifer Rachel Cochran | post-doc | 2002-2004 | MIT (Neurotree) |
| James A. Van Deventer | post-doc | 2011-2015 | MIT |
BETA: Related publications
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Publications
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| Horton BL, D'Souza AD, Zagorulya M, et al. (2023) Overcoming lung cancer immunotherapy resistance by combining non-toxic variants of IL-12 and IL-2. Jci Insight |
| Mehta NK, Pradhan RV, Soleimany AP, et al. (2020) Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines. Nature Biomedical Engineering |
| Ma L, Dichwalkar T, Chang JYH, et al. (2019) Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science (New York, N.Y.). 365: 162-168 |
| Momin N, Mehta NK, Bennett NR, et al. (2019) Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy. Science Translational Medicine. 11 |
| Dréau D, Moore LJ, Wu M, et al. (2019) Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma. Frontiers in Oncology. 9: 330 |
| Rothschilds A, Tzeng A, Mehta NK, et al. (2019) Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models. Oncoimmunology. 8: e1558678 |
| Angelini A, Miyabe Y, Newsted D, et al. (2018) Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis. Nature Communications. 9: 1461 |
| Kelly RL, Le D, Zhao J, et al. (2018) Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries. Journal of Molecular Biology. 430: 119-130 |
| Green DJ, O'Steen S, Lin Y, et al. (2017) CD38 bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B cell malignancies. Blood |
| Kelly RL, Zhao J, Le D, et al. (2017) Nonspecificity in a nonimmune human scFv repertoire. Mabs. 0 |