Philip Biggin
Affiliations: | 2011- | Biochemistry | University of Oxford, Oxford, United Kingdom |
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"Philip Biggin"Mean distance: 106866
Collaborators
Sign in to add collaborator| Lucia Sivilotti | collaborator | UCL | |
| Derek Bowie | collaborator | 2011- | Oxford |
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Publications
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| Zaki AM, Çınaroğlu SS, Rahman T, et al. (2024) Plasticity of the selectivity filter is essential for permeation in lysosomal TPC2 channels. Proceedings of the National Academy of Sciences of the United States of America. 121: e2320153121 |
| Seiferth D, Biggin PC. (2024) Exploring the influence of pore shape on conductance and permeation. Biophysical Journal |
| Wu Z, Smith K, Gerondopoulos A, et al. (2024) Molecular basis for pH sensing in the KDEL trafficking receptor. Structure (London, England : 1993) |
| Bharambe N, Li Z, Seiferth D, et al. (2024) Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment. Nature Communications. 15: 2967 |
| Larsen AH, Perozzo AM, Biggin PC, et al. (2024) Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface. The Journal of Biological Chemistry. 300: 105717 |
| Bay Y, Venskutonytė R, Frantsen SM, et al. (2023) Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The Febs Journal |
| Viscarra F, Chrestia JF, Sanchez Y, et al. (2023) Side Groups Convert the α7 Nicotinic Receptor Agonist Ether Quinuclidine into a Type I Positive Allosteric Modulator. Acs Chemical Neuroscience. 14: 2876-2887 |
| Seiferth D, Tucker SJ, Biggin PC. (2023) Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts. Physical Chemistry Chemical Physics : Pccp. 25: 17596-17608 |
| Gibbs E, Klemm E, Seiferth D, et al. (2023) Conformational transitions and allosteric modulation in a heteromeric glycine receptor. Nature Communications. 14: 1363 |
| Seiferth D, Biggin PC, Tucker SJ. (2022) When is a hydrophobic gate not a hydrophobic gate? The Journal of General Physiology. 154 |