Andrea de Bartolomeis

Affiliations: 
Neuroscience University School of Medicine of Naples Federico II Italy 
Area:
Schizophrenia, psychosis, antipsychotics, synapse, Homer
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"Andrea de Bartolomeis"
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Andrea de Bartolomeis MD PhD Biosketch

Andrea de Bartolomeis M.D., Ph.D. is Associate Professor of Psychiatry, director of the Section of Psychiatry and Treatment Resistant Psychosis program at Department of Neuroscience, University School of Medicine of Napoli Federico II,
He is also the Director of the Residency program in Psychiatry

Andrea de Bartolomeis received his medical degree and his residency training in psychiatry at the University of Naples Federico II, Italy.

He completed his postdoctoral training as recipient of Fogarty Fellowship in psychopharmacology and molecular pathophysiology of schizophrenia with NIMH in Bethesda MD (USA) first at Clinical Neuroscience Branch (1989-1992) and then at Experimental Therapeutics Branch (1993-1995) where he contributed to develop a novel method for quantitation of synaptic dopamine in vivo in primates, using PET and microdialysis simultaneously. This method was instrumental for the first demonstration in vivo by PET and 11C-raclopride of enhanced release of dopamine after amphetamine challenge in striatum of schizophrenics patients compared to normal controls.
He has been Visiting scientist at Neuroendocrinology Branch of NIMH, Bethesda, MD, USA, and Guest scientists at NIMH ETB and Anxiety Mood Disorder Program in several occasion from 1995 to 2000, for collaborating project

In 1998 he received from the University of Naples a Ph.D. degree in Methodology of Communication Science.
In 2001 he became chief of the Laboratory of Molecular and Translational Psychiatry.

The research interest of Andrea de Bartolomeis includes: the molecular
pathophysiology of psychosis, CNS gene expression modulation by psychotropic
drugs, and augmentation strategy in psychosis pharmacotherapy.

He has been principal investigator or co-investigator on several research and training grants as well on clinical trials from public and drug company sources.

He is member of the American Society for Neuroscience, International Society for Schizophrenia Research, New York Academy of Sciences, Italian Society of Neuroscience, Italian Society of Psychopathology, European Collegium of Neuropsychopharmacology.
He has been elected in the board of directors of the Italian Society for Neuroscience for the years 2012-2015.
He is member of board of directors of the Italian Chapter of International Bipolar Disorders Society

He has authored articles, book chapters, and published abstracts on molecular mechanisms of antipsychotics as well as on schizophrenia pathophysiology and molecular imaging of dopaminergic system.

He published his works in: Nature Medicine, Nature Translational Psychiatry, Proceedings of National Academy of Sciences, Biological Psychiatry, Neuropsychopharmacology, Molecular Brain Research, Synapse, Cerebral Blood flow and Metabolism, Neuroreport, Current Drug Design, European Neuropsychopharmacology, Annals of New York Academy of Sciences, Neuroscience, Molecular Neurobiology, Psychiatry Research, Journal of Psychiatry Resarch.

His recent research is focusing on antipsychotics impact on postsynaptic density proteins and molecular mechanisms of antipsychotics action as well as on clinical and molecular implication of antipsychotic treatment-resistant schizophrenia.
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Mean distance: 17.93 (cluster 19)
 
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Lamsma J, Raine A, Kia SM, et al. (2024) Structural brain abnormalities and aggressive behaviour in schizophrenia: Mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium. Medrxiv : the Preprint Server For Health Sciences
Fornaro M, Caiazza C, Billeci M, et al. (2024) Nutraceuticals and phytoceuticals in the treatment of schizophrenia: a systematic review and network meta-analysis. Research Square
Omlor W, Rabe F, Fuchs S, et al. (2023) Estimating multimodal brain variability in schizophrenia spectrum disorders: A worldwide ENIGMA study. Biorxiv : the Preprint Server For Biology
Jiang Y, Luo C, Wang J, et al. (2023) Two neurostructural subtypes: results of machine learning on brain images from 4,291 individuals with schizophrenia. Medrxiv : the Preprint Server For Health Sciences
Vellucci L, Ciccarelli M, Buonaguro EF, et al. (2023) The Neurobiological Underpinnings of Obsessive-Compulsive Symptoms in Psychosis, Translational Issues for Treatment-Resistant Schizophrenia. Biomolecules. 13
Rossano F, Caiazza C, Zotti N, et al. (2023) The efficacy, safety, and adverse events of azapirones in anxiety disorders: A systematic review and meta-analysis of randomized controlled trials. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 76: 23-51
D'Urso G, Magliacano A, Dell'Osso B, et al. (2023) Effects of strict COVID-19 lockdown on patients with obsessive-compulsive disorder compared to a clinical and a nonclinical sample. European Psychiatry : the Journal of the Association of European Psychiatrists. 66: e45
D'Urso G, Pomes MV, Magliacano A, et al. (2023) Depression and Anxiety Symptoms "Among the Waves" of the COVID-19 Pandemic in Obsessive Compulsive Disorder and Adjustment Disorder Patients. Healthcare (Basel, Switzerland). 11
De Simone G, Mazza B, Vellucci L, et al. (2023) Schizophrenia Synaptic Pathology and Antipsychotic Treatment in the Framework of Oxidative and Mitochondrial Dysfunction: Translational Highlights for the Clinics and Treatment. Antioxidants (Basel, Switzerland). 12
Rossano F, Caiazza C, Sobrino A, et al. (2023) Efficacy and safety of selegiline across different psychiatric disorders: A systematic review and meta-analysis of oral and transdermal formulations. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 72: 60-78
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