Darren Boehning - Publications

Affiliations: 
University of Texas Medical Branch, Galveston, TX 
Area:
Apoptosis, Calcium, Neurodegeneration, Gaseous Neurotransmission

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Akimzhanov AM, Boehning D. Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling. Proceedings of the National Academy of Sciences of the United States of America. 112: 11876-80. PMID 26351666 DOI: 10.1073/pnas.1509929112  1
2015 Borahay MA, Al-Hendy A, Kilic GS, Boehning D. Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy. Molecular Medicine (Cambridge, Mass.). 21: 242-256. PMID 25879625 DOI: 10.2119/molmed.2014.00053  1
2015 Borahay MA, Vincent K, Motamedi M, Sbrana E, Kilic GS, Al-Hendy A, Boehning D. Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study. American Journal of Obstetrics and Gynecology. PMID 25840272 DOI: 10.1016/j.ajog.2015.03.055  1
2015 Hedgepeth SC, Garcia MI, Wagner LE, Rodriguez AM, Chintapalli SV, Snyder RR, Hankins GD, Henderson BR, Brodie KM, Yule DI, van Rossum DB, Boehning D. The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release. The Journal of Biological Chemistry. 290: 7304-13. PMID 25645916 DOI: 10.1074/jbc.M114.611186  1
2014 Borahay MA, Kilic GS, Yallampalli C, Snyder RR, Hankins GD, Al-Hendy A, Boehning D. Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells. The Journal of Biological Chemistry. 289: 35075-86. PMID 25359773 DOI: 10.1074/jbc.M114.583575  1
2014 Fos C, Becart S, Canonigo Balancio AJ, Boehning D, Altman A. Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells. Science Signaling. 7: ra93. PMID 25270259 DOI: 10.1126/scisignal.2005565  1
2014 Nicholls P, Bujalowski PJ, Epstein HF, Boehning DF, Barral JM, Oberhauser AF. Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke. Febs Letters. 588: 3977-81. PMID 25240199 DOI: 10.1016/j.febslet.2014.09.013  1
2014 Safren N, El Ayadi A, Chang L, Terrillion CE, Gould TD, Boehning DF, Monteiro MJ. Ubiquilin-1 overexpression increases the lifespan and delays accumulation of Huntingtin aggregates in the R6/2 mouse model of Huntington's disease. Plos One. 9: e87513. PMID 24475300 DOI: 10.1371/journal.pone.0087513  1
2013 Pavlovsky AA, Boehning D, Li D, Zhang Y, Fan X, Green TA. Psychological stress, cocaine and natural reward each induce endoplasmic reticulum stress genes in rat brain. Neuroscience. 246: 160-9. PMID 23644055 DOI: 10.1016/j.neuroscience.2013.04.057  1
2013 Brooks NC, Marshall AH, Qa'aty N, Hiyama Y, Boehning D, Jeschke MG. XBP-1s is linked to suppressed gluconeogenesis in the Ebb phase of burn injury. Molecular Medicine (Cambridge, Mass.). 19: 72-8. PMID 23508570 DOI: 10.2119/molmed.2012.00348  1
2013 El Ayadi A, Stieren ES, Barral JM, Boehning D. Ubiquilin-1 and protein quality control in Alzheimer disease. Prion. 7: 164-9. PMID 23360761 DOI: 10.4161/pri.23711  1
2013 Wang X, Xiong LW, El Ayadi A, Boehning D, Putkey JA. The calmodulin regulator protein, PEP-19, sensitizes ATP-induced Ca2+ release. The Journal of Biological Chemistry. 288: 2040-8. PMID 23204517 DOI: 10.1074/jbc.M112.411314  1
2013 Akimzhanov AM, Barral JM, Boehning D. Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release. Cell Calcium. 53: 152-8. PMID 23122728 DOI: 10.1016/j.ceca.2012.10.002  1
2012 El Ayadi A, Stieren ES, Barral JM, Oberhauser AF, Boehning D. Purification and aggregation of the amyloid precursor protein intracellular domain. Journal of Visualized Experiments : Jove. e4204. PMID 22952038 DOI: 10.3791/4204  1
2012 El Ayadi A, Stieren ES, Barral JM, Boehning D. Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688. Proceedings of the National Academy of Sciences of the United States of America. 109: 13416-21. PMID 22847417 DOI: 10.1073/pnas.1206786109  1
2012 Clark SL, Rodriguez AM, Snyder RR, Hankins GD, Boehning D. Structure-Function Of The Tumor Suppressor BRCA1. Computational and Structural Biotechnology Journal. 1. PMID 22737296 DOI: 10.5936/csbj.201204005  1
2012 Brooks NC, Song J, Boehning D, Kraft R, Finnerty CC, Herndon DN, Jeschke MG. Propranolol improves impaired hepatic phosphatidylinositol 3-kinase/akt signaling after burn injury. Molecular Medicine (Cambridge, Mass.). 18: 707-11. PMID 22396018 DOI: 10.2119/molmed.2011.00277  1
2012 Song J, Zhang XJ, Boehning D, Brooks NC, Herndon DN, Jeschke MG. Measurement of hepatic protein fractional synthetic rate with stable isotope labeling technique in thapsigargin stressed HepG2 cells. International Journal of Biological Sciences. 8: 265-71. PMID 22298954 DOI: 10.7150/ijbs.3660  1
2012 Song J, Finnerty CC, Herndon DN, Kraft R, Boehning D, Brooks NC, Tompkins RG, Jeschke MG. Thermal injury activates the eEF2K-dependent eEF2 pathway in pediatric patients. Jpen. Journal of Parenteral and Enteral Nutrition. 36: 596-602. PMID 22269896 DOI: 10.1177/0148607111422234  1
2012 Jeschke MG, Finnerty CC, Herndon DN, Song J, Boehning D, Tompkins RG, Baker HV, Gauglitz GG. Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response. Annals of Surgery. 255: 370-8. PMID 22241293 DOI: 10.1097/SLA.0b013e31823e76e7  1
2012 Jeschke MG, Boehning D. Endoplasmic reticulum stress and insulin resistance post-trauma: similarities to type 2 diabetes. Journal of Cellular and Molecular Medicine. 16: 437-44. PMID 21812914 DOI: 10.1111/j.1582-4934.2011.01405.x  1
2012 Boehning D, Barral JM. Protein quality control in Alzheimers disease: The contentious role of ubiquilin-1 Future Neurology. 7: 5-8. DOI: 10.2217/fnl.11.62  1
2012 Akimzhanov AM, Boehning D. IP3R function in cells of the immune system Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1: 329-339. DOI: 10.1002/wmts.27  1
2011 Stieren ES, El Ayadi A, Xiao Y, Siller E, Landsverk ML, Oberhauser AF, Barral JM, Boehning D. Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein. The Journal of Biological Chemistry. 286: 35689-98. PMID 21852239 DOI: 10.1074/jbc.M111.243147  1
2011 Akimzhanov AM, Boehning D. Monitoring dynamic changes in mitochondrial calcium levels during apoptosis using a genetically encoded calcium sensor. Journal of Visualized Experiments : Jove. PMID 21490580 DOI: 10.3791/2579  1
2011 Jeschke MG, Kraft R, Song J, Gauglitz GG, Cox RA, Brooks NC, Finnerty CC, Kulp GA, Herndon DN, Boehning D. Insulin protects against hepatic damage postburn. Molecular Medicine (Cambridge, Mass.). 17: 516-22. PMID 21267509 DOI: 10.2119/molmed.2010.00166  1
2010 Boehning DF. Molecular architecture of the inositol 1,4,5-trisphosphate receptor pore. Current Topics in Membranes. 66: 191-207. PMID 22353481 DOI: 10.1016/S1063-5823(10)66009-7  1
2010 Gauglitz GG, Halder S, Boehning DF, Kulp GA, Herndon DN, Barral JM, Jeschke MG. Post-burn hepatic insulin resistance is associated with endoplasmic reticulum (ER) stress. Shock (Augusta, Ga.). 33: 299-305. PMID 22011639 DOI: 10.1097/SHK.0b013e3181b2f439  1
2010 Stieren E, Werchan WP, El Ayadi A, Li F, Boehning D. FAD mutations in amyloid precursor protein do not directly perturb intracellular calcium homeostasis. Plos One. 5: e11992. PMID 20700539 DOI: 10.1371/journal.pone.0011992  1
2010 Akimzhanov AM, Wang X, Sun J, Boehning D. T-cell receptor complex is essential for Fas signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 107: 15105-10. PMID 20696918 DOI: 10.1073/pnas.1005419107  1
2009 Jeschke MG, Gauglitz GG, Song J, Kulp GA, Finnerty CC, Cox RA, Barral JM, Herndon DN, Boehning D. Calcium and ER stress mediate hepatic apoptosis after burn injury. Journal of Cellular and Molecular Medicine. 13: 1857-65. PMID 20141609 DOI: 10.1111/j.1582-4934.2009.00644.x  1
2009 Song J, Finnerty CC, Herndon DN, Boehning D, Jeschke MG. Severe burn-induced endoplasmic reticulum stress and hepatic damage in mice. Molecular Medicine (Cambridge, Mass.). 15: 316-20. PMID 19603103 DOI: 10.2119/molmed.2009.00048  1
2009 Jordan PM, Ojeda LD, Thonhoff JR, Gao J, Boehning D, Yu Y, Wu P. Generation of spinal motor neurons from human fetal brain-derived neural stem cells: role of basic fibroblast growth factor. Journal of Neuroscience Research. 87: 318-32. PMID 18803285 DOI: 10.1002/jnr.21856  1
2008 Qin X, Kwansa H, Bucci E, Doré S, Boehning D, Shugar D, Koehler RC. Role of heme oxygenase-2 in pial arteriolar response to acetylcholine in mice with and without transfusion of cell-free hemoglobin polymers. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R498-504. PMID 18495834 DOI: 10.1152/ajpregu.00188.2008  1
2008 Gauglitz GG, Song J, Herndon DN, Finnerty CC, Boehning D, Barral JM, Jeschke MG. Characterization of the inflammatory response during acute and post-acute phases after severe burn. Shock (Augusta, Ga.). 30: 503-7. PMID 18391855 DOI: 10.1097/SHK.0b013e31816e3373  1
2008 Steinmann C, Landsverk ML, Barral JM, Boehning D. Requirement of inositol 1,4,5-trisphosphate receptors for tumor-mediated lymphocyte apoptosis. The Journal of Biological Chemistry. 283: 13506-9. PMID 18364356 DOI: 10.1074/jbc.C800029200  1
2007 Jeschke MG, Boehning DF, Finnerty CC, Herndon DN. Effect of insulin on the inflammatory and acute phase response after burn injury. Critical Care Medicine. 35: S519-23. PMID 17713402 DOI: 10.1097/01.CCM.0000282027.10288.10  1
2007 Cummins SF, De Vries MR, Hill KS, Boehning D, Nagle GT. Gene identification and evidence for expression of G protein alpha subunits, phospholipase C, and an inositol 1,4,5-trisphosphate receptor in Aplysia californica rhinophore. Genomics. 90: 110-20. PMID 17498918 DOI: 10.1016/j.ygeno.2007.03.020  1
2007 Li Y, Boehning DF, Qian T, Popov VL, Weinman SA. Hepatitis C virus core protein increases mitochondrial ROS production by stimulation of Ca2+ uniporter activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2474-85. PMID 17392480 DOI: 10.1096/fj.06-7345com  1
2007 Moore A, Kolokoltsov A, Boehning D, Albrecht T, Davey R. Specific targeting and delivery of virus envelope-coated nanoparticle cargoes into receptor-bearing cells and subcellular compartments 2007 Nsti Nanotechnology Conference and Trade Show - Nsti Nanotech 2007, Technical Proceedings. 2: 370-373.  1
2006 Wozniak AL, Wang X, Stieren ES, Scarbrough SG, Elferink CJ, Boehning D. Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis. The Journal of Cell Biology. 175: 709-14. PMID 17130290 DOI: 10.1083/jcb.200608035  1
2005 Boehning D, van Rossum DB, Patterson RL, Snyder SH. A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways. Proceedings of the National Academy of Sciences of the United States of America. 102: 1466-71. PMID 15665074 DOI: 10.1073/pnas.0409650102  1
2004 Patterson RL, Boehning D, Snyder SH. Inositol 1,4,5-trisphosphate receptors as signal integrators. Annual Review of Biochemistry. 73: 437-65. PMID 15189149 DOI: 10.1146/annurev.biochem.73.071403.161303  1
2004 Boehning D, Sedaghat L, Sedlak TW, Snyder SH. Heme oxygenase-2 is activated by calcium-calmodulin. The Journal of Biological Chemistry. 279: 30927-30. PMID 15175337 DOI: 10.1074/jbc.C400222200  1
2004 Watkins CC, Boehning D, Kaplin AI, Rao M, Ferris CD, Snyder SH. Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic/noncholinergic neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 101: 2631-5. PMID 14983060 DOI: 10.1073/pnas.0308695100  1
2004 van Rossum DB, Patterson RL, Kiselyov K, Boehning D, Barrow RK, Gill DL, Snyder SH. Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition. Proceedings of the National Academy of Sciences of the United States of America. 101: 2323-7. PMID 14983008 DOI: 10.1073/pnas.0308565100  1
2004 Boehning D, Patterson RL, Snyder SH. Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate. Cell Cycle (Georgetown, Tex.). 3: 252-4. PMID 14726673  1
2003 Boehning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nature Cell Biology. 5: 1051-61. PMID 14608362 DOI: 10.1038/ncb1063  1
2003 Boehning D, Moon C, Sharma S, Hurt KJ, Hester LD, Ronnett GV, Shugar D, Snyder SH. Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2. Neuron. 40: 129-37. PMID 14527438 DOI: 10.1016/S0896-6273(03)00596-8  1
2003 Boehning D, Snyder SH. Novel neural modulators. Annual Review of Neuroscience. 26: 105-31. PMID 14527267 DOI: 10.1146/annurev.neuro.26.041002.131047  1
2002 Boehning D, Snyder SH. Circadian rhythms. Carbon monoxide and clocks. Science (New York, N.Y.). 298: 2339-40. PMID 12493901 DOI: 10.1126/science.1080339  1
2001 Boehning D, Joseph SK, Mak DO, Foskett JK. Single-channel recordings of recombinant inositol trisphosphate receptors in mammalian nuclear envelope. Biophysical Journal. 81: 117-24. PMID 11423400  1
2001 Boehning D, Mak DO, Foskett JK, Joseph SK. Molecular determinants of ion permeation and selectivity in inositol 1,4,5-trisphosphate receptor Ca2+ channels. The Journal of Biological Chemistry. 276: 13509-12. PMID 11278266 DOI: 10.1074/jbc.C100094200  1
2000 Boehning D, Joseph SK. Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors. The Embo Journal. 19: 5450-9. PMID 11032812 DOI: 10.1093/emboj/19.20.5450  1
2000 Boehning D, Joseph SK. Functional properties of recombinant type I and type III inositol 1, 4,5-trisphosphate receptor isoforms expressed in COS-7 cells. The Journal of Biological Chemistry. 275: 21492-9. PMID 10764774 DOI: 10.1074/jbc.M001724200  1
2000 Joseph SK, Bokkala S, Boehning D, Zeigler S. Factors determining the composition of inositol trisphosphate receptor hetero-oligomers expressed in COS cells. The Journal of Biological Chemistry. 275: 16084-90. PMID 10747920 DOI: 10.1074/jbc.M000506200  1
1999 Joseph SK, Boehning D, Bokkala S, Watkins R, Widjaja J. Biosynthesis of inositol trisphosphate receptors: selective association with the molecular chaperone calnexin. The Biochemical Journal. 342: 153-61. PMID 10432312 DOI: 10.1042/0264-6021:3420153  1
1997 Joseph SK, Boehning D, Pierson S, Nicchitta CV. Membrane insertion, glycosylation, and oligomerization of inositol trisphosphate receptors in a cell-free translation system. The Journal of Biological Chemistry. 272: 1579-88. PMID 8999831 DOI: 10.1074/jbc.272.3.1579  1
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