| Year |
Citation |
Score |
| 2024 |
Wang L, Wen X, Morrison J. Imperfect gold standard gene sets yield inaccurate evaluation of causal gene identification methods. Communications Biology. 7: 873. PMID 39020054 DOI: 10.1038/s42003-024-06482-1 |
0.676 |
|
| 2024 |
Boye C, Kalita CA, Findley AS, Alazizi A, Wei J, Wen X, Pique-Regi R, Luca F. Characterization of caffeine response regulatory variants in vascular endothelial cells. Elife. 13. PMID 38334359 DOI: 10.7554/eLife.85235 |
0.321 |
|
| 2023 |
Yin X, Li J, Bose D, Okamoto J, Kwon A, Jackson AU, Silva LF, Oravilahti A, Stringham HM, Ripatti S, Daly M, Palotie A, Scott LJ, Burant CF, Fauman EB, ... Wen X, et al. Metabolome-wide Mendelian randomization characterizes heterogeneous and shared causal effects of metabolites on human health. Medrxiv : the Preprint Server For Health Sciences. PMID 37425837 DOI: 10.1101/2023.06.26.23291721 |
0.654 |
|
| 2023 |
Han SK, McNulty MT, Benway CJ, Wen P, Greenberg A, Onuchic-Whitford AC, Jang D, Flannick J, Burtt NP, Wilson PC, Humphreys BD, Wen X, Han Z, Lee D, Sampson MG. Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs. Nature Communications. 14: 2229. PMID 37076491 DOI: 10.1038/s41467-023-37691-7 |
0.363 |
|
| 2023 |
Okamoto J, Wang L, Yin X, Luca F, Pique-Regi R, Helms A, Im HK, Morrison J, Wen X. Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits. American Journal of Human Genetics. 110: 44-57. PMID 36608684 DOI: 10.1016/j.ajhg.2022.12.002 |
0.722 |
|
| 2022 |
Yin X, Bose D, Kwon A, Hanks SC, Jackson AU, Stringham HM, Welch R, Oravilahti A, Fernandes Silva L, Locke AE, Fuchsberger C, Service SK, Erdos MR, Bonnycastle LL, Kuusisto J, ... ... Wen X, et al. Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk. American Journal of Human Genetics. PMID 36055244 DOI: 10.1016/j.ajhg.2022.08.007 |
0.717 |
|
| 2022 |
Hukku A, Sampson MG, Luca F, Pique-Regi R, Wen X. Analyzing and reconciling colocalization and transcriptome-wide association studies from the perspective of inferential reproducibility. American Journal of Human Genetics. 109: 825-837. PMID 35523146 DOI: 10.1016/j.ajhg.2022.04.005 |
0.361 |
|
| 2022 |
Yin X, Chan LS, Bose D, Jackson AU, VandeHaar P, Locke AE, Fuchsberger C, Stringham HM, Welch R, Yu K, Fernandes Silva L, Service SK, Zhang D, Hector EC, Young E, ... ... Wen X, et al. Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci. Nature Communications. 13: 1644. PMID 35347128 DOI: 10.1038/s41467-022-29143-5 |
0.704 |
|
| 2021 |
Findley AS, Monziani A, Richards AL, Rhodes K, Ward MC, Kalita CA, Alazizi A, Pazokitoroudi A, Sankararaman S, Wen X, Lanfear DE, Pique-Regi R, Gilad Y, Luca F. Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions. Elife. 10. PMID 33988505 DOI: 10.7554/eLife.67077 |
0.353 |
|
| 2021 |
de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, ... ... Wen X, et al. Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell. PMID 33864768 DOI: 10.1016/j.cell.2021.03.050 |
0.362 |
|
| 2021 |
Barbeira AN, Bonazzola R, Gamazon ER, Liang Y, Park Y, Kim-Hellmuth S, Wang G, Jiang Z, Zhou D, Hormozdiari F, Liu B, Rao A, Hamel AR, Pividori MD, Aguet F, ... ... Wen X, et al. Exploiting the GTEx resources to decipher the mechanisms at GWAS loci. Genome Biology. 22: 49. PMID 33499903 DOI: 10.1186/s13059-020-02252-4 |
0.705 |
|
| 2020 |
Quick C, Wen X, Abecasis G, Boehnke M, Kang HM. Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis. Plos Genetics. 16: e1009060. PMID 33320851 DOI: 10.1371/journal.pgen.1009060 |
0.35 |
|
| 2020 |
Hukku A, Pividori M, Luca F, Pique-Regi R, Im HK, Wen X. Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations. American Journal of Human Genetics. PMID 33308443 DOI: 10.1016/j.ajhg.2020.11.012 |
0.32 |
|
| 2020 |
Barbeira AN, Melia OJ, Liang Y, Bonazzola R, Wang G, Wheeler HE, Aguet F, Ardlie KG, Wen X, Im HK. Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification. Genetic Epidemiology. PMID 32964524 DOI: 10.1002/gepi.22346 |
0.631 |
|
| 2020 |
Pividori M, Rajagopal PS, Barbeira A, Liang Y, Melia O, Bastarache L, Park Y, Consortium G, Wen X, Im HK. PhenomeXcan: Mapping the genome to the phenome through the transcriptome. Science Advances. 6. PMID 32917697 DOI: 10.1126/Sciadv.Aba2083 |
0.493 |
|
| 2020 |
Kim-Hellmuth S, Aguet F, Oliva M, Muñoz-Aguirre M, Kasela S, Wucher V, Castel SE, Hamel AR, Viñuela A, Roberts AL, Mangul S, Wen X, Wang G, Barbeira AN, Garrido-Martín D, et al. Cell type-specific genetic regulation of gene expression across human tissues. Science (New York, N.Y.). 369. PMID 32913075 DOI: 10.1126/Science.Aaz8528 |
0.678 |
|
| 2020 |
Gay NR, Gloudemans M, Antonio ML, Abell NS, Balliu B, Park Y, Martin AR, Musharoff S, Rao AS, Aguet F, Barbeira AN, Bonazzola R, Hormozdiari F, Ardlie KG, ... ... Wen X, et al. Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx. Genome Biology. 21: 233. PMID 32912333 DOI: 10.1186/S13059-020-02113-0 |
0.338 |
|
| 2020 |
Zhang Y, Quick C, Yu K, Barbeira A, Luca F, Pique-Regi R, Kyung Im H, Wen X. PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis. Genome Biology. 21: 232. PMID 32912253 DOI: 10.1186/S13059-020-02026-Y |
0.449 |
|
| 2020 |
Tsoi L, Zhang Z, Stuart P, Zhang Y, Patrick M, Zhang H, Wen X, Nair R, Elder J. 303 Allele specific accessibility analysis to decipher molecular mechanism of psoriasis-associated loci Journal of Investigative Dermatology. 140: S37. DOI: 10.1016/J.Jid.2020.03.309 |
0.348 |
|
| 2019 |
Hukku A, Quick C, Luca F, Pique-Regi R, Wen X. BAGSE: A Bayesian Hierarchical Model Approach for Gene Set Enrichment Analysis. Bioinformatics (Oxford, England). PMID 31702789 DOI: 10.1093/Bioinformatics/Btz831 |
0.424 |
|
| 2019 |
Findley AS, Richards AL, Petrini C, Alazizi A, Doman E, Shanku AG, Davis GO, Hauff N, Sorokin Y, Wen X, Pique-Regi R, Luca F. Interpreting Coronary Artery Disease Risk Through Gene-Environment Interactions in Gene Regulation. Genetics. PMID 31492806 DOI: 10.1534/Genetics.119.302419 |
0.445 |
|
| 2018 |
Patrick MT, Stuart PE, Raja K, Gudjonsson JE, Tejasvi T, Yang J, Chandran V, Das S, Callis-Duffin K, Ellinghaus E, Enerbäck C, Esko T, Franke A, Kang HM, Krueger GG, ... ... Wen X, et al. Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients. Nature Communications. 9: 4178. PMID 30301895 DOI: 10.1038/S41467-018-06672-6 |
0.32 |
|
| 2018 |
Kalita CA, Brown CD, Freiman A, Isherwood J, Wen X, Pique-Regi R, Luca F. High throughput characterization of genetic effects on DNA:protein binding and gene transcription. Genome Research. PMID 30254052 DOI: 10.1101/Gr.237354.118 |
0.408 |
|
| 2018 |
Nielsen JB, Thorolfsdottir RB, Fritsche LG, Zhou W, Skov MW, Graham SE, Herron TJ, McCarthy S, Schmidt EM, Sveinbjornsson G, Surakka I, Mathis MR, Yamazaki M, Crawford RD, Gabrielsen ME, ... ... Wen X, et al. Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. Nature Genetics. PMID 30061737 DOI: 10.1038/S41588-018-0171-3 |
0.353 |
|
| 2018 |
Gillies CE, Putler R, Menon R, Otto E, Yasutake K, Nair V, Hoover P, Lieb D, Li S, Eddy S, Fermin D, McNulty MT, Hacohen N, Kiryluk K, ... ... Wen X, et al. An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome. American Journal of Human Genetics. PMID 30057032 DOI: 10.1016/J.Ajhg.2018.07.004 |
0.45 |
|
| 2018 |
Gamazon ER, Segrè AV, van de Bunt M, Wen X, Xi HS, Hormozdiari F, Ongen H, Konkashbaev A, Derks EM, Aguet F, Quan J, Nicolae DL, Eskin E, Kellis M, et al. Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation. Nature Genetics. PMID 29955180 DOI: 10.1038/S41588-018-0154-4 |
0.495 |
|
| 2018 |
Patrick M, Stuart P, Yang J, Raja K, Yang Y, Madu D, Tejasvi T, Voorhees J, Kang H, Gudjonsson J, Abecasis G, Nair R, Wen X, Elder J, Tsoi L. 742 Identification of psoriasis-associated genes using genetically predicted transcriptomes Journal of Investigative Dermatology. 138: S126. DOI: 10.1016/J.Jid.2018.03.752 |
0.402 |
|
| 2017 |
Kalita CA, Moyerbrailean GA, Brown C, Wen X, Luca F, Pique-Regi R. QuASAR-MPRA: Accurate allele-specific analysis for massively parallel reporter assays. Bioinformatics (Oxford, England). PMID 29028988 DOI: 10.1093/Bioinformatics/Btx598 |
0.424 |
|
| 2017 |
Richards AL, Watza D, Findley A, Alazizi A, Wen X, Pai AA, Pique-Regi R, Luca F. Environmental perturbations lead to extensive directional shifts in RNA processing. Plos Genetics. 13: e1006995. PMID 29023442 DOI: 10.1371/Journal.Pgen.1006995 |
0.342 |
|
| 2017 |
Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, ... ... Wen X, et al. Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. Nature Communications. 8: 15382. PMID 28537254 DOI: 10.1038/Ncomms15382 |
0.399 |
|
| 2017 |
Wen X, Pique-Regi R, Luca F. Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization. Plos Genetics. 13: e1006646. PMID 28278150 DOI: 10.1371/Journal.Pgen.1006646 |
0.43 |
|
| 2016 |
Moyerbrailean GA, Richards AL, Kurtz D, Kalita CA, Davis GO, Harvey CT, Alazizi A, Watza D, Sorokin Y, Hauff N, Zhou X, Wen X, Pique-Regi R, Luca F. High-throughput allele-specific expression across 250 environmental conditions. Genome Research. 26: 1627-1638. PMID 27934696 DOI: 10.1101/Gr.209759.116 |
0.456 |
|
| 2016 |
Scott LJ, Erdos MR, Huyghe JR, Welch RP, Beck AT, Wolford BN, Chines PS, Didion JP, Narisu N, Stringham HM, Taylor DL, Jackson AU, Vadlamudi S, Bonnycastle LL, Kinnunen L, ... ... Wen X, et al. The genetic regulatory signature of type 2 diabetes in human skeletal muscle. Nature Communications. 7: 11764. PMID 27353450 DOI: 10.1038/Ncomms11764 |
0.362 |
|
| 2016 |
Wen X, Lee Y, Luca F, Pique-Regi R. Efficient Integrative Multi-SNP Association Analysis via Deterministic Approximation of Posteriors. American Journal of Human Genetics. PMID 27236919 DOI: 10.1016/J.Ajhg.2016.03.029 |
0.435 |
|
| 2016 |
Moyerbrailean GA, Kalita CA, Harvey CT, Wen X, Luca F, Pique-Regi R. Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding? Plos Genetics. 12: e1005875. PMID 26901046 DOI: 10.1371/Journal.Pgen.1005875 |
0.407 |
|
| 2016 |
Wen X. Molecular QTL discovery incorporating genomic annotations using Bayesian false discovery rate control Annals of Applied Statistics. 10: 1619-1638. DOI: 10.1214/16-Aoas952 |
0.439 |
|
| 2016 |
Wen X. Robust Bayesian FDR Control Using Bayes Factors, with Applications to Multi-tissue eQTL Discovery Statistics in Biosciences. 1-22. DOI: 10.1007/S12561-016-9153-0 |
0.357 |
|
| 2016 |
Chen H, Wen X, Guan Y, Min J, Wen Y, Yang H, Chen X, Li Y, Yang X, Tang T. Effect of particle size on the flame retardancy of poly(butylene succinate)/Mg(OH)2 composites Fire and Materials. DOI: 10.1002/fam.2355 |
0.324 |
|
| 2015 |
Stuart PE, Nair RP, Tsoi LC, Tejasvi T, Das S, Kang HM, Ellinghaus E, Chandran V, Callis-Duffin K, Ike R, Li Y, Wen X, Enerbäck C, Gudjonsson JE, Kõks S, et al. Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. American Journal of Human Genetics. PMID 26626624 DOI: 10.1016/J.Ajhg.2015.10.019 |
0.351 |
|
| 2015 |
Moyerbrailean GA, Davis GO, Harvey CT, Watza D, Wen X, Pique-Regi R, Luca F. A high-throughput RNA-seq approach to profile transcriptional responses. Scientific Reports. 5: 14976. PMID 26510397 DOI: 10.1038/Srep14976 |
0.336 |
|
| 2015 |
Wen X, Luca F, Pique-Regi R. Cross-population joint analysis of eQTLs: fine mapping and functional annotation. Plos Genetics. 11: e1005176. PMID 25906321 DOI: 10.1371/Journal.Pgen.1005176 |
0.401 |
|
| 2015 |
Wen X. Bayesian model comparison in genetic association analysis: linear mixed modeling and SNP set testing. Biostatistics (Oxford, England). 16: 701-12. PMID 25796429 DOI: 10.1093/Biostatistics/Kxv009 |
0.36 |
|
| 2015 |
Harvey CT, Moyerbrailean GA, Davis GO, Wen X, Luca F, Pique-Regi R. QuASAR: quantitative allele-specific analysis of reads. Bioinformatics (Oxford, England). 31: 1235-42. PMID 25480375 DOI: 10.1093/Bioinformatics/Btu802 |
0.427 |
|
| 2015 |
Ardlie KG, DeLuca DS, Segrè AV, Sullivan TJ, Young TR, Gelfand ET, Trowbridge CA, Maller JB, Tukiainen T, Lek M, Ward LD, Kheradpour P, Iriarte B, Meng Y, Palmer CD, ... ... Wen X, et al. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans Science. 348: 648-660. DOI: 10.1126/science.1262110 |
0.508 |
|
| 2014 |
Wen X, Stephens M. BAYESIAN METHODS FOR GENETIC ASSOCIATION ANALYSIS WITH HETEROGENEOUS SUBGROUPS: FROM META-ANALYSES TO GENE-ENVIRONMENT INTERACTIONS. The Annals of Applied Statistics. 8: 176-203. PMID 26413181 DOI: 10.1214/13-Aoas695 |
0.599 |
|
| 2014 |
Li S, Mukherjee B, Taylor JM, Rice KM, Wen X, Rice JD, Stringham HM, Boehnke M. The role of environmental heterogeneity in meta-analysis of gene-environment interactions with quantitative traits. Genetic Epidemiology. 38: 416-29. PMID 24801060 DOI: 10.1002/Gepi.21810 |
0.381 |
|
| 2014 |
Wen X. Bayesian model selection in complex linear systems, as illustrated in genetic association studies. Biometrics. 70: 73-83. PMID 24350677 DOI: 10.1111/Biom.12112 |
0.319 |
|
| 2013 |
Lonsdale J, Thomas J, Salvatore M, Phillips R, Lo E, Shad S, Hasz R, Walters G, Garcia F, Young N, Foster B, Moser M, Karasik E, Gillard B, Ramsey K, ... ... Wen X, et al. The Genotype-Tissue Expression (GTEx) project Nature Genetics. 45: 580-585. PMID 23715323 DOI: 10.1038/Ng.2653 |
0.445 |
|
| 2013 |
Flutre T, Wen X, Pritchard J, Stephens M. A statistical framework for joint eQTL analysis in multiple tissues. Plos Genetics. 9: e1003486. PMID 23671422 DOI: 10.1371/Journal.Pgen.1003486 |
0.536 |
|
| 2011 |
Maranville JC, Luca F, Richards AL, Wen X, Witonsky DB, Baxter S, Stephens M, Di Rienzo A. Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes. Plos Genetics. 7: e1002162. PMID 21750684 DOI: 10.1371/Journal.Pgen.1002162 |
0.55 |
|
| 2010 |
Wen X, Stephens M. USING LINEAR PREDICTORS TO IMPUTE ALLELE FREQUENCIES FROM SUMMARY OR POOLED GENOTYPE DATA. The Annals of Applied Statistics. 4: 1158-1182. PMID 21479081 DOI: 10.1214/10-Aoas338 |
0.552 |
|
| 2010 |
De la Cruz O, Wen X, Ke B, Song M, Nicolae DL. Gene, region and pathway level analyses in whole-genome studies. Genetic Epidemiology. 34: 222-31. PMID 20013942 DOI: 10.1002/Gepi.20452 |
0.467 |
|
| 2008 |
Coop G, Wen X, Ober C, Pritchard JK, Przeworski M. High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science (New York, N.Y.). 319: 1395-8. PMID 18239090 DOI: 10.1126/Science.1151851 |
0.317 |
|
| 2008 |
Wen X, Nicolae DL. Association studies for untyped markers with TUNA. Bioinformatics (Oxford, England). 24: 435-7. PMID 18057020 DOI: 10.1093/Bioinformatics/Btm603 |
0.343 |
|
| 2006 |
Conrad DF, Jakobsson M, Coop G, Wen X, Wall JD, Rosenberg NA, Pritchard JK. A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nature Genetics. 38: 1251-60. PMID 17057719 DOI: 10.1038/Ng1911 |
0.322 |
|
| 2006 |
Nicolae DL, Wen X, Voight BF, Cox NJ. Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set. Plos Genetics. 2: e67. PMID 16680197 DOI: 10.1371/Journal.Pgen.0020067 |
0.34 |
|
| 2006 |
Voight BF, Kudaravalli S, Wen X, Pritchard JK. A map of recent positive selection in the human genome. Plos Biology. 4: e72. PMID 16494531 DOI: 10.1371/Journal.Pbio.0040072 |
0.35 |
|
| 2005 |
Zöllner S, Wen X, Pritchard JK. Association mapping and fine mapping with TreeLD. Bioinformatics (Oxford, England). 21: 3168-70. PMID 15855250 DOI: 10.1093/Bioinformatics/Bti453 |
0.327 |
|
| 2004 |
Zöllner S, Wen X, Hanchard NA, Herbert MA, Ober C, Pritchard JK. Evidence for extensive transmission distortion in the human genome. American Journal of Human Genetics. 74: 62-72. PMID 14681832 DOI: 10.1086/381131 |
0.386 |
|
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