Year |
Citation |
Score |
2020 |
Wei T, Cheng Q, Farbiak L, Anderson DG, Langer R, Siegwart DJ. Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for CRISPR/Cas-Based Genome Editing. Acs Nano. PMID 32697075 DOI: 10.1021/Acsnano.0C04707 |
0.303 |
|
2020 |
Xiong H, Liu S, Wei T, Cheng Q, Siegwart DJ. Theranostic dendrimer-based lipid nanoparticles containing PEGylated BODIPY dyes for tumor imaging and systemic mRNA delivery in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32629133 DOI: 10.1016/J.Jconrel.2020.06.030 |
0.352 |
|
2020 |
Wei T, Cheng Q, Min YL, Olson EN, Siegwart DJ. Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing. Nature Communications. 11: 3232. PMID 32591530 DOI: 10.1038/S41467-020-17029-3 |
0.318 |
|
2020 |
Xue L, Yan Y, Kos P, Chen X, Siegwart DJ. PEI fluorination reduces toxicity and promotes liver-targeted siRNA delivery. Drug Delivery and Translational Research. PMID 32506259 DOI: 10.1007/S13346-020-00790-9 |
0.411 |
|
2020 |
Zhou K, Johnson LT, Xiong H, Barrios S, Minnig JT, Yan Y, Abram B, Yu X, Siegwart DJ. The hydrophobic domain structure of linear-dendritic poly(ethylene glycol) lipids affects RNA delivery of lipid nanoparticles. Molecular Pharmaceutics. PMID 32267707 DOI: 10.1021/Acs.Molpharmaceut.9B01288 |
0.355 |
|
2020 |
Cheng Q, Wei T, Farbiak L, Johnson LT, Dilliard SA, Siegwart DJ. Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing. Nature Nanotechnology. PMID 32251383 DOI: 10.1038/S41565-020-0669-6 |
0.319 |
|
2020 |
Yu X, Liu S, Cheng Q, Wei T, Lee S, Zhang D, Siegwart DJ. Lipid-Modified Aminoglycosides for mRNA Delivery to the Liver. Advanced Healthcare Materials. e1901487. PMID 32108440 DOI: 10.1002/Adhm.201901487 |
0.372 |
|
2019 |
Dong Y, Siegwart DJ, Anderson DG. Strategies, design, and chemistry in siRNA delivery systems. Advanced Drug Delivery Reviews. PMID 31102606 DOI: 10.1016/J.Addr.2019.05.004 |
0.376 |
|
2018 |
Elkassih SA, Kos P, Xiong H, Siegwart DJ. Degradable redox-responsive disulfide-based nanogel drug carriers via dithiol oxidation polymerization. Biomaterials Science. PMID 30462102 DOI: 10.1039/C8Bm01120F |
0.412 |
|
2017 |
Miller JB, Kos P, Tieu V, Zhou K, Siegwart DJ. Development of Cationic Quaternary Ammonium Sulfonamide Amino Lipids (CSALs) for Nucleic Acid Delivery. Acs Applied Materials & Interfaces. PMID 29286232 DOI: 10.1021/Acsami.7B15982 |
0.344 |
|
2017 |
Yan Y, Xiong H, Zhang X, Cheng Q, Siegwart DJ. Systemic mRNA Delivery to the Lungs by Functional Polyester-based Carriers. Biomacromolecules. PMID 29141136 DOI: 10.1021/Acs.Biomac.7B01356 |
0.33 |
|
2017 |
Senevirathne SA, Washington KE, Miller JB, Biewer MC, Oupicky D, Siegwart DJ, Stefan MC. HDAC Inhibitor Conjugated Polymeric Prodrug Micelles for Doxorubicin Delivery. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 5: 2106-2114. PMID 28630710 DOI: 10.1039/C6Tb03038F |
0.614 |
|
2017 |
Xiong H, Zuo H, Yan Y, Occhialini G, Zhou K, Wan Y, Siegwart DJ. High-Contrast Fluorescence Detection of Metastatic Breast Cancer Including Bone and Liver Micrometastases via Size-Controlled pH-Activatable Water-Soluble Probes. Advanced Materials (Deerfield Beach, Fla.). PMID 28563903 DOI: 10.1002/Adma.201700131 |
0.303 |
|
2016 |
Miller JB, Zhang S, Kos P, Xiong H, Zhou K, Perelman SS, Zhu H, Siegwart DJ. Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA. Angewandte Chemie (International Ed. in English). PMID 27981708 DOI: 10.1002/Anie.201610209 |
0.327 |
|
2016 |
Yan Y, Zhou K, Xiong H, Miller JB, Motea EA, Boothman DA, Liu L, Siegwart DJ. Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors. Biomaterials. 118: 84-93. PMID 27974266 DOI: 10.1016/J.Biomaterials.2016.12.001 |
0.31 |
|
2016 |
Zhou K, Kos P, Yan Y, Xiong H, Min YL, Kinghorn KA, Minnig JT, Miller JB, Siegwart DJ. Intercalation-mediated nucleic acid nanoparticles for siRNA delivery. Chemical Communications (Cambridge, England). 52: 12155-12158. PMID 27711272 DOI: 10.1039/C6Cc06024B |
0.317 |
|
2016 |
Yan Y, Liu L, Xiong H, Miller JB, Zhou K, Kos P, Huffman KE, Elkassih S, Norman JW, Carstens R, Kim J, Minna JD, Siegwart DJ. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621434 DOI: 10.1073/Pnas.1606886113 |
0.319 |
|
2016 |
Zhou K, Nguyen LH, Miller JB, Yan Y, Kos P, Xiong H, Li L, Hao J, Minnig JT, Zhu H, Siegwart DJ. Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model. Proceedings of the National Academy of Sciences of the United States of America. PMID 26729861 DOI: 10.1073/Pnas.1520756113 |
0.312 |
|
2016 |
Hao J, Elkassih S, Siegwart DJ. Progress towards the Synthesis of Amino Polyesters via Ring-Opening Polymerization (ROP) of Functional Lactones Synlett. 27: 2285-2292. DOI: 10.1055/S-0035-1562505 |
0.364 |
|
2015 |
Rainbolt EA, Miller JB, Washington KE, Senevirathne SA, Biewer MC, Siegwart DJ, Stefan MC. Fine-tuning thermoresponsive functional poly(ε-caprolactone)s to enhance micelle stability and drug loading. Journal of Materials Chemistry. B. 3: 1779-1787. PMID 32262251 DOI: 10.1039/C4Tb02016B |
0.605 |
|
2015 |
Yan Y, Xue L, Miller JB, Zhou K, Kos P, Elkassih S, Liu L, Nagai A, Xiong H, Siegwart DJ. One-pot Synthesis of Functional Poly(amino ester sulfide)s and Utility in Delivering pDNA and siRNA. Polymer. 72: 271-280. PMID 26726270 DOI: 10.1016/J.Polymer.2015.02.020 |
0.46 |
|
2015 |
Nagai A, Miller JB, Du J, Kos P, Stefan MC, Siegwart DJ. Correction: Biocompatible organic charge transfer complex nanoparticles based on a semi-crystalline cellulose template. Chemical Communications (Cambridge, England). PMID 26552587 DOI: 10.1039/C5Cc90504D |
0.546 |
|
2015 |
Hao J, Kos P, Zhou K, Miller JB, Xue L, Yan Y, Xiong H, Elkassih S, Siegwart DJ. Rapid Synthesis of a Lipocationic Polyester Library via Ring-Opening Polymerization of Functional Valerolactones for Efficacious siRNA Delivery. Journal of the American Chemical Society. PMID 26166403 DOI: 10.1021/Jacs.5B03429 |
0.449 |
|
2015 |
Nagai A, Miller JB, Du J, Kos P, Stefan MC, Siegwart DJ. Biocompatible organic charge transfer complex nanoparticles based on a semi-crystalline cellulose template. Chemical Communications (Cambridge, England). PMID 26110741 DOI: 10.1039/C5Cc03822G |
0.553 |
|
2015 |
Rainbolt EA, Miller JB, Washington KE, Senevirathne SA, Biewer MC, Siegwart DJ, Stefan MC. Fine-tuning thermoresponsive functional poly(ε-caprolactone)s to enhance micelle stability and drug loading Journal of Materials Chemistry B. 3: 1779-1787. DOI: 10.1039/c4tb02016b |
0.547 |
|
2014 |
Yan Y, Siegwart DJ. Scalable synthesis and derivation of functional polyesters bearing ene and epoxide side chains Polymer Chemistry. 5: 1362-1371. DOI: 10.1039/C3Py01474F |
0.425 |
|
2012 |
Siegwart DJ, Leiendecker M, Langer R, Anderson DG. Automated ARGET ATRP Accelerates Catalyst Optimization for the Synthesis of Thiol-Functionalized Polymers. Macromolecules. 45: 1254-1261. PMID 23599541 DOI: 10.1021/Ma3000219 |
0.402 |
|
2012 |
Siegwart DJ, Oh JK, Matyjaszewski K. ATRP in the design of functional materials for biomedical applications. Progress in Polymer Science. 37: 18-37. PMID 23525884 DOI: 10.1016/J.Progpolymsci.2011.08.001 |
0.536 |
|
2012 |
Averick SE, Paredes E, Irastorza A, Shrivats AR, Srinivasan A, Siegwart DJ, Magenau AJ, Cho HY, Hsu E, Averick AA, Kim J, Liu S, Hollinger JO, Das SR, Matyjaszewski K. Preparation of cationic nanogels for nucleic acid delivery. Biomacromolecules. 13: 3445-9. PMID 22967138 DOI: 10.1021/Bm301166S |
0.489 |
|
2012 |
Eltoukhy AA, Siegwart DJ, Alabi CA, Rajan JS, Langer R, Anderson DG. Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity. Biomaterials. 33: 3594-603. PMID 22341939 DOI: 10.1016/J.Biomaterials.2012.01.046 |
0.447 |
|
2011 |
Siegwart DJ, Whitehead KA, Nuhn L, Sahay G, Cheng H, Jiang S, Ma M, Lytton-Jean A, Vegas A, Fenton P, Levins CG, Love KT, Lee H, Cortez C, Collins SP, et al. Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America. 108: 12996-3001. PMID 21784981 DOI: 10.1073/Pnas.1106379108 |
0.403 |
|
2011 |
Ma M, Liu WF, Hill PS, Bratlie KM, Siegwart DJ, Chin J, Park M, Guerreiro J, Anderson DG. Development of cationic polymer coatings to regulate foreign-body responses. Advanced Materials (Deerfield Beach, Fla.). 23: H189-94. PMID 21567481 DOI: 10.1002/Adma.201100513 |
0.336 |
|
2011 |
Cheng H, Hill PS, Siegwart DJ, Vacanti N, Lytton-Jean AK, Cho SW, Ye A, Langer R, Anderson DG. A novel family of biodegradable poly(ester amide) elastomers. Advanced Materials (Deerfield Beach, Fla.). 23: H95-100. PMID 21394790 DOI: 10.1002/Adma.201003482 |
0.314 |
|
2011 |
Pritchard CD, O'Shea TM, Siegwart DJ, Calo E, Anderson DG, Reynolds FM, Thomas JA, Slotkin JR, Woodard EJ, Langer R. An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate. Biomaterials. 32: 587-97. PMID 20880573 DOI: 10.1016/J.Biomaterials.2010.08.106 |
0.373 |
|
2010 |
Cho HY, Gao H, Srinivasan A, Hong J, Bencherif SA, Siegwart DJ, Paik HJ, Hollinger JO, Matyjaszewski K. Rapid cellular internalization of multifunctional star polymers prepared by atom transfer radical polymerization. Biomacromolecules. 11: 2199-203. PMID 20831270 DOI: 10.1021/Bm1006272 |
0.697 |
|
2010 |
Cheng H, Kastrup CJ, Ramanathan R, Siegwart DJ, Ma M, Bogatyrev SR, Xu Q, Whitehead KA, Langer R, Anderson DG. Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. Acs Nano. 4: 625-31. PMID 20121215 DOI: 10.1021/Nn901319Y |
0.324 |
|
2009 |
Bencherif SA, Siegwart DJ, Srinivasan A, Horkay F, Hollinger JO, Washburn NR, Matyjaszewski K. Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization. Biomaterials. 30: 5270-8. PMID 19592087 DOI: 10.1016/J.Biomaterials.2009.06.011 |
0.537 |
|
2009 |
Siegwart DJ, Srinivasan A, Bencherif SA, Karunanidhi A, Oh JK, Vaidya S, Jin R, Hollinger JO, Matyjaszewski K. Cellular uptake of functional nanogels prepared by inverse miniemulsion ATRP with encapsulated proteins, carbohydrates, and gold nanoparticles. Biomacromolecules. 10: 2300-9. PMID 19572639 DOI: 10.1021/Bm9004904 |
0.525 |
|
2009 |
Bencherif SA, Gao H, Srinivasan A, Siegwart DJ, Hollinger JO, Washburn NR, Matyjaszewski K. Cell-adhesive star polymers prepared by ATRP. Biomacromolecules. 10: 1795-803. PMID 19518096 DOI: 10.1021/Bm900213U |
0.65 |
|
2008 |
Siegwart DJ, Bencherif SA, Srinivasan A, Hollinger JO, Matyjaszewski K. Synthesis, characterization, and in vitro cell culture viability of degradable poly(N-isopropylacrylamide-co-5,6-benzo-2-methylene-1,3-dioxepane)-based polymers and crosslinked gels. Journal of Biomedical Materials Research. Part A. 87: 345-58. PMID 18181103 DOI: 10.1002/Jbm.A.31708 |
0.536 |
|
2008 |
Oh JK, Drumright R, Siegwart DJ, Matyjaszewski K. The development of microgels/nanogels for drug delivery applications Progress in Polymer Science (Oxford). 33: 448-477. DOI: 10.1016/J.Progpolymsci.2008.01.002 |
0.523 |
|
2008 |
Siegwart DJ, Oh JK, Gao H, Bencherif SA, Perineau F, Bohaty AK, Hollinger JO, Matyjaszewski K. Biotin-, pyrene-, and GRGDS-functionalized polymers and nanogels via ATRP and end group modification Macromolecular Chemistry and Physics. 209: 2179-2193. DOI: 10.1002/Macp.200800337 |
0.664 |
|
2007 |
Oh JK, Siegwart DJ, Matyjaszewski K. Synthesis and biodegradation of nanogels as delivery carriers for carbohydrate drugs. Biomacromolecules. 8: 3326-31. PMID 17894465 DOI: 10.1021/Bm070381+ |
0.502 |
|
2007 |
Oh JK, Siegwart DJ, Lee HI, Sherwood G, Peteanu L, Hollinger JO, Kataoka K, Matyjaszewski K. Biodegradable nanogels prepared by atom transfer radical polymerization as potential drug delivery carriers: synthesis, biodegradation, in vitro release, and bioconjugation. Journal of the American Chemical Society. 129: 5939-45. PMID 17439215 DOI: 10.1021/Ja069150L |
0.706 |
|
2007 |
Siegwart DJ, Wu W, Mandalaywala M, Tamir M, Sarbu T, Silverstein MS, Kowalewski T, Hollinger JO, Matyjaszewski K. Solvent induced morphologies of poly(methyl methacrylate-b-ethylene oxide-b-methyl methacrylate) triblock copolymers synthesized by atom transfer radical polymerization Polymer. 48: 7279-7290. DOI: 10.1016/J.Polymer.2007.10.009 |
0.498 |
|
2006 |
Huang J, Jia S, Siegwart DJ, Kowalewski T, Matyjaszewski K. Cover Picture: Macromol. Chem. Phys. 9/2006 Macromolecular Chemistry and Physics. 207: 793-793. DOI: 10.1002/Macp.200690014 |
0.543 |
|
2006 |
Hucing J, Jia S, Siegwart DJ, Kowalewski T, Matyjaszewski K. Synthesis and characterization of styrene/butyl acrylate linear and star block copolymers via atom transfer radical polymerization Macromolecular Chemistry and Physics. 207: 801-811. DOI: 10.1002/Macp.200600003 |
0.459 |
|
2005 |
Gao H, Siegwart DJ, Jahed N, Sarbu T, Matyjaszewski K. Characterization of α,ω-dihydroxypolystyrene by gradient polymer elution chromatography and two-dimensional liquid chromatography Designed Monomers and Polymers. 8: 533-546. DOI: 10.1163/156855505774597713 |
0.631 |
|
2004 |
Sarbu T, Lin KY, Spanswick J, Gil RR, Siegwart DJ, Matyjaszewski K. Synthesis of hydroxy-telechelic poly(methyl acrylate) and polystyrene by atom transfer radical coupling Macromolecules. 37: 9694-9700. DOI: 10.1021/Ma0484375 |
0.486 |
|
2004 |
Sarbu T, Lin KY, Ell J, Siegwart DJ, Spanswick J, Matyjaszewski K. Polystyrene with designed molecular weight distribution by atom transfer radical coupling Macromolecules. 37: 3120-3127. DOI: 10.1021/Ma035901H |
0.421 |
|
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