| Year |
Citation |
Score |
| 2019 |
Greene A, Pascarelli K, Broccoli D, Perkins E. Engineering Synthetic Chromosomes by Sequential Loading of Multiple Genomic Payloads over 100 Kilobase Pairs in Size. Molecular Therapy. Methods & Clinical Development. 13: 463-473. PMID 31193384 DOI: 10.1016/J.Omtm.2019.04.006 |
0.398 |
|
| 2015 |
May CD, Garnett J, Ma X, Landers SM, Ingram DR, Demicco EG, Al Sannaa GA, Vu T, Han L, Zhang Y, Kivlin CM, Bolshakov S, Kalam AA, Liu J, Zhou F, ... Broccoli D, et al. AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas. Bmc Cancer. 15: 901. PMID 26573603 DOI: 10.1186/S12885-015-1916-3 |
0.367 |
|
| 2013 |
Plantinga MJ, Pascarelli KM, Merkel AS, Lazar AJ, von Mehren M, Lev D, Broccoli D. Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles. Molecular Cancer Research : McR. 11: 557-67. PMID 23505069 DOI: 10.1158/1541-7786.Mcr-13-0013 |
0.457 |
|
| 2012 |
Doyle KR, Mitchell MA, Roberts CL, James S, Johnson JE, Zhou Y, von Mehren M, Lev D, Kipling D, Broccoli D. Validating a gene expression signature proposed to differentiate liposarcomas that use different telomere maintenance mechanisms. Oncogene. 31: 265-6; author reply . PMID 21706060 DOI: 10.1038/Onc.2011.225 |
0.31 |
|
| 2011 |
Pascarelli K, Plantinga M, Doyle K, Roberts C, Zhou Y, Mehren Mv, Lev D, Broccoli D. Abstract 2019: An epigenetic reactivation screen identifies pathways important in pleomorphic liposarcomas Cancer Research. 71: 2019-2019. DOI: 10.1158/1538-7445.Am2011-2019 |
0.339 |
|
| 2010 |
Mitchell MA, Johnson JE, Pascarelli K, Beeharry N, Chiourea M, Gagos S, Lev D, von Mehren M, Kipling D, Broccoli D. Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres. Molecular Cancer Therapeutics. 9: 682-92. PMID 20197395 DOI: 10.1158/1535-7163.Mct-09-0705 |
0.393 |
|
| 2009 |
Caslini C, Connelly JA, Serna A, Broccoli D, Hess JL. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Molecular and Cellular Biology. 29: 4519-26. PMID 19528237 DOI: 10.1128/Mcb.00195-09 |
0.496 |
|
| 2007 |
Deng Z, Dheekollu J, Broccoli D, Dutta A, Lieberman PM. The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation. Current Biology : Cb. 17: 1989-95. PMID 18006317 DOI: 10.1016/J.Cub.2007.10.054 |
0.492 |
|
| 2007 |
Johnson JE, Gettings EJ, Schwalm J, Pei J, Testa JR, Litwin S, von Mehren M, Broccoli D. Whole-genome profiling in liposarcomas reveals genetic alterations common to specific telomere maintenance mechanisms. Cancer Research. 67: 9221-8. PMID 17909028 DOI: 10.1158/0008-5472.CAN-07-1133 |
0.336 |
|
| 2007 |
Johnson JE, Broccoli D. Telomere maintenance in sarcomas. Current Opinion in Oncology. 19: 377-82. PMID 17545803 DOI: 10.1097/Cco.0B013E3281214423 |
0.42 |
|
| 2005 |
von Mehren M, Varkonyi RJ, Johnson JE, Broccoli D. Mechanisms of telomere maintenance in liposarcomas (LPS). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 9017. PMID 27945548 DOI: 10.1200/Jco.2005.23.16_Suppl.9017 |
0.493 |
|
| 2005 |
Johnson JE, Varkonyi RJ, Schwalm J, Cragle R, Klein-Szanto A, Patchefsky A, Cukierman E, von Mehren M, Broccoli D. Multiple mechanisms of telomere maintenance exist in liposarcomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5347-55. PMID 16061847 DOI: 10.1158/1078-0432.CCR-05-0684 |
0.462 |
|
| 2005 |
Beeharry N, Broccoli D. Telomere dynamics in response to chemotherapy. Current Molecular Medicine. 5: 187-96. PMID 15974872 DOI: 10.2174/1566524053586554 |
0.303 |
|
| 2004 |
Broccoli D. Function, replication and structure of the mammalian telomere. Cytotechnology. 45: 3-12. PMID 19003238 DOI: 10.1007/s10616-004-5120-6 |
0.44 |
|
| 2004 |
Xin Z, Broccoli D. Manipulating mouse telomeres: models of tumorigenesis and aging. Cytogenetic and Genome Research. 105: 471-8. PMID 15237236 DOI: 10.1159/000078221 |
0.468 |
|
| 2004 |
Razak ZR, Varkonyi RJ, Kulp-McEliece M, Caslini C, Testa JR, Murphy ME, Broccoli D. p53 differentially inhibits cell growth depending on the mechanism of telomere maintenance. Molecular and Cellular Biology. 24: 5967-77. PMID 15199150 DOI: 10.1128/MCB.24.13.5967-5977.2004 |
0.356 |
|
| 2004 |
Ibanez de Caceres I, Frolova N, Varkonyi RJ, Dulaimi E, Meropol NJ, Broccoli D, Cairns P. Telomerase is frequently activated in tumors with microsatellite instability. Cancer Biology & Therapy. 3: 289-92. PMID 14726659 |
0.335 |
|
| 2003 |
Deng Z, Atanasiu C, Burg JS, Broccoli D, Lieberman PM. Telomere repeat binding factors TRF1, TRF2, and hRAP1 modulate replication of Epstein-Barr virus OriP. Journal of Virology. 77: 11992-2001. PMID 14581536 DOI: 10.1128/Jvi.77.22.11992-12001.2003 |
0.36 |
|
| 2003 |
Armbruster BN, Etheridge KT, Broccoli D, Counter CM. Putative telomere-recruiting domain in the catalytic subunit of human telomerase. Molecular and Cellular Biology. 23: 3237-46. PMID 12697823 DOI: 10.1128/Mcb.23.9.3237-3246.2003 |
0.352 |
|
| 2001 |
Grobelny JV, Kulp-McEliece M, Broccoli D. Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway. Human Molecular Genetics. 10: 1953-61. PMID 11555632 |
0.398 |
|
| 2000 |
Grobelny JV, Godwin AK, Broccoli D. ALT-associated PML bodies are present in viable cells and are enriched in cells in the G(2)/M phase of the cell cycle. Journal of Cell Science. 113: 4577-85. PMID 11082050 |
0.361 |
|
| 1999 |
Kipling D, Wynford-Thomas D, Jones CJ, Akbar A, Aspinall R, Bacchetti S, Blasco MA, Broccoli D, DePinho RA, Edwards DR, Effros RB, Harley CB, Lansdorp PM, Linskens MH, Prowse KR, et al. Telomere-dependent senescence. Nature Biotechnology. 17: 313-4. PMID 10207859 DOI: 10.1038/7827 |
0.386 |
|
| 1999 |
Karlseder J, Broccoli D, Dai Y, Hardy S, de Lange T. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science (New York, N.Y.). 283: 1321-5. PMID 10037601 DOI: 10.1126/Science.283.5406.1321 |
0.63 |
|
| 1997 |
Broccoli D, Smogorzewska A, Chong L, de Lange T. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nature Genetics. 17: 231-5. PMID 9326950 DOI: 10.1038/ng1097-231 |
0.659 |
|
| 1997 |
Broccoli D, Chong L, Oelmann S, Fernald AA, Marziliano N, van Steensel B, Kipling D, Le Beau MM, de Lange T. Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains. Human Molecular Genetics. 6: 69-76. PMID 9002672 DOI: 10.1093/Hmg/6.1.69 |
0.609 |
|
| 1996 |
Broccoli D, Godley LA, Donehower LA, Varmus HE, de Lange T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Molecular and Cellular Biology. 16: 3765-72. PMID 8668193 DOI: 10.1128/Mcb.16.7.3765 |
0.602 |
|
| 1995 |
Garagna S, Broccoli D, Redi CA, Searle JB, Cooke HJ, Capanna E. Robertsonian metacentrics of the house mouse lose telomeric sequences but retain some minor satellite DNA in the pericentromeric area. Chromosoma. 103: 685-92. PMID 7664615 DOI: 10.1007/Bf00344229 |
0.412 |
|
| 1995 |
Broccoli D, Young JW, de Lange T. Telomerase activity in normal and malignant hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9082-6. PMID 7568077 DOI: 10.1073/Pnas.92.20.9082 |
0.531 |
|
| 1995 |
Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T. A human telomeric protein. Science (New York, N.Y.). 270: 1663-7. PMID 7502076 DOI: 10.1126/Science.270.5242.1663 |
0.658 |
|
| 1994 |
Broccoli D, Cooke HJ. Effect of telomeres on the interphase location of adjacent regions of the human X chromosome. Experimental Cell Research. 212: 308-13. PMID 8187823 DOI: 10.1006/excr.1994.1148 |
0.449 |
|
| 1994 |
Bayne RA, Broccoli D, Taggart MH, Thomson EJ, Farr CJ, Cooke HJ. Sandwiching of a gene within 12 kb of a functional telomere and alpha satellite does not result in silencing. Human Molecular Genetics. 3: 539-46. PMID 8069295 DOI: 10.1093/Hmg/3.4.539 |
0.467 |
|
| 1992 |
Broccoli D, Miller OJ, Miller DA. Isolation and characterization of a mouse subtelomeric sequence. Chromosoma. 101: 442-7. PMID 1618025 DOI: 10.1007/BF00582838 |
0.317 |
|
| 1991 |
Broccoli D, Trevor KT, Miller OJ, Miller DA. Isolation of a variant family of mouse minor satellite DNA that hybridizes preferentially to chromosome 4. Genomics. 10: 68-74. PMID 2045111 DOI: 10.1016/0888-7543(91)90485-W |
0.31 |
|
| 1990 |
Broccoli D, Miller OJ, Miller DA. Relationship of mouse minor satellite DNA to centromere activity. Cytogenetics and Cell Genetics. 54: 182-6. PMID 2265565 |
0.402 |
|
| 1989 |
Broccoli D, Paweletz N, Vig BK. Sequence of centromere separation: characterization of multicentric chromosomes in a rat cell line. Chromosoma. 98: 13-22. PMID 2766876 DOI: 10.1007/BF00293330 |
0.36 |
|
| 1989 |
Vig BK, Paweletz N, Broccoli D. Centromere separation and aneuploidy: a lesson from multicentric chromosomes. Progress in Clinical and Biological Research. 318: 137-48. PMID 2696963 |
0.376 |
|
| 1988 |
Vig BK, Broccoli D. Sequence of centromere separation: differential replication of pericentric heterochromatin in multicentric chromosomes. Chromosoma. 96: 311-7. PMID 3383702 DOI: 10.1007/BF00286919 |
0.382 |
|
| 1986 |
Zinkowski RP, Vig BK, Broccoli D. Characterization of kinetochores in multicentric chromosomes. Chromosoma. 94: 243-8. PMID 3539553 DOI: 10.1007/BF00290851 |
0.375 |
|
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