| Year |
Citation |
Score |
| 2020 |
Ding S, Ghavami M, Butler JH, Merino EF, Slebodnick C, Cassera MB, Carlier PR. Probing the B- & C-rings of the antimalarial tetrahydro-β-carboline MMV008138 for steric and conformational constraints. Bioorganic & Medicinal Chemistry Letters. 127520. PMID 32898696 DOI: 10.1016/J.Bmcl.2020.127520 |
0.357 |
|
| 2020 |
Ding S, Fike KR, Klemba M, Carlier PR. In vitro and in vivo evaluation of the antimalarial MMV665831 and structural analogs. Bioorganic & Medicinal Chemistry Letters. 30: 127348. PMID 32738996 DOI: 10.1016/J.Bmcl.2020.127348 |
0.354 |
|
| 2019 |
Deora N, Carlier PR. A computational study of regioselectivity in aluminum hydride ring-opening of cis- and trans-4-t-butyl and 3-methylcyclohexene oxides. Organic & Biomolecular Chemistry. PMID 31528943 DOI: 10.1039/C9Ob01675A |
0.764 |
|
| 2019 |
Cagašová K, Ghavami M, Yao ZK, Carlier PR. Questioning the γ-gauche effect: stereoassignment of 1,3-disubstituted-tetrahydro-β-carbolines using H-H coupling constants. Organic & Biomolecular Chemistry. PMID 31232413 DOI: 10.1039/C9Ob01139K |
0.325 |
|
| 2019 |
Mutunga JM, Ma M, Chen QH, Hartsel JA, Wong DM, Ding S, Totrov M, Carlier PR, Bloomquist JR. Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates. International Journal of Environmental Research and Public Health. 16. PMID 31035318 DOI: 10.3390/Ijerph16091500 |
0.368 |
|
| 2018 |
Carlier PR, Chen QH, Verma A, Wong DM, Mutunga JM, Müller J, Islam R, Shimozono AM, Tong F, Li J, Totrov M, Bloomquist JR. Select β- and γ-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of versus human acetylcholinesterase. Pesticide Biochemistry and Physiology. 151: 32-39. PMID 30524149 DOI: 10.1016/J.Pestbp.2018.02.003 |
0.655 |
|
| 2018 |
Cheung J, Mahmood A, Kalathur R, Liu L, Carlier PR. Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance. Structure (London, England : 1993). 26: 130-136.e2. PMID 29276037 DOI: 10.1016/J.Str.2017.11.021 |
0.356 |
|
| 2017 |
Clements JS, Islam R, Sun B, Tong F, Gross AD, Bloomquist JR, Carlier PR. N'-mono- and N, N'-diacyl derivatives of benzyl and arylhydrazines as contact insecticides against adult Anopheles gambiae. Pesticide Biochemistry and Physiology. 143: 33-38. PMID 29183608 DOI: 10.1016/J.Pestbp.2017.10.001 |
0.341 |
|
| 2017 |
Ghavami M, Merino EF, Yao Z, Elahi R, Simpson M, Fernandez-Murga M, Butler JH, Casasanta M, Krai P, Totrov M, Slade DJ, Carlier PR, Cassera MB. Biological studies and target-engagement of the 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)-targeting antimalarial agent (1R,3S)-MMV008138 and analogs. Acs Infectious Diseases. PMID 29072835 DOI: 10.1021/Acsinfecdis.7B00159 |
0.331 |
|
| 2017 |
Han Q, Wong DM, Robinson H, Ding H, Lam PC, Totrov MM, Carlier PR, Li J. Crystal structure of acetylcholinesterase catalytic subunits of the malaria vector Anopheles gambiae. Insect Science. PMID 28247978 DOI: 10.1111/1744-7917.12450 |
0.665 |
|
| 2017 |
Carlier PR, Bloomquist JR, Totrov M, Li J. Discovery of Species-selective and Resistance-breaking Anticholinesterase Insecticides for the Malaria Mosquito. Current Medicinal Chemistry. PMID 28176636 DOI: 10.2174/0929867324666170206130024 |
0.352 |
|
| 2016 |
Mutunga JM, Chen QH, Wong DM, Lam PC, Li J, Totrov MM, Gross AD, Carlier PR, Bloomquist JR. Bivalent Carbamates as Novel Control Agents of the Malaria Mosquito, Anopheles gambiae. Chimia. 70: 704-708. PMID 27779928 DOI: 10.2533/Chimia.2016.704 |
0.717 |
|
| 2016 |
Ghavami M, Dapper CH, Dalal S, Holzschneider K, Klemba M, Carlier PR. Parallel inhibition of amino acid efflux and growth of erythrocytic Plasmodium falciparum by mefloquine and non-piperidine analogs: Implication for the mechanism of antimalarial action. Bioorganic & Medicinal Chemistry Letters. PMID 27544402 DOI: 10.1016/J.Bmcl.2016.08.005 |
0.32 |
|
| 2015 |
Camerino E, Wong DM, Tong F, Körber F, Gross AD, Islam R, Viayna E, Mutunga JM, Li J, Totrov MM, Bloomquist JR, Carlier PR. Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. PMID 26386602 DOI: 10.1016/J.Bmcl.2015.09.019 |
0.768 |
|
| 2015 |
Mutunga JM, Anderson TD, Craft DT, Gross AD, Swale DR, Tong F, Wong DM, Carlier PR, Bloomquist JR. Carbamate and pyrethroid resistance in the akron strain of Anopheles gambiae. Pesticide Biochemistry and Physiology. 121: 116-21. PMID 26047119 DOI: 10.1016/J.Pestbp.2015.03.001 |
0.337 |
|
| 2015 |
Franklin MC, Cheung J, Rudolph MJ, Burshteyn F, Cassidy M, Gary E, Hillerich B, Yao ZK, Carlier PR, Totrov M, Love JD. Structural Genomics for Drug Design against the Pathogen Coxiella burnetii. Proteins. PMID 26033498 DOI: 10.1002/Prot.24841 |
0.668 |
|
| 2015 |
Yao ZK, Krai PM, Merino EF, Simpson ME, Slebodnick C, Cassera MB, Carlier PR. Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure-activity studies. Bioorganic & Medicinal Chemistry Letters. 25: 1515-9. PMID 25754494 DOI: 10.1016/J.Bmcl.2015.02.020 |
0.35 |
|
| 2015 |
Verma A, Wong DM, Islam R, Tong F, Ghavami M, Mutunga JM, Slebodnick C, Li J, Viayna E, Lam PC, Totrov MM, Bloomquist JR, Carlier PR. 3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae. Bioorganic & Medicinal Chemistry. 23: 1321-40. PMID 25684426 DOI: 10.1016/J.Bmc.2015.01.026 |
0.775 |
|
| 2014 |
Temeyer KB, Tong F, Totrov MM, Tuckow AP, Chen QH, Carlier PR, Pérez de León AA, Bloomquist JR. Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): construction, expression and biochemical properties of the G119S orthologous mutant. Parasites & Vectors. 7: 577. PMID 25491113 DOI: 10.1186/S13071-014-0577-4 |
0.31 |
|
| 2014 |
Bloomquist JR, Mutunga JM, Islam RM, Verma A, Ma M, Totrov MM, Carlier PR. Voltage-sensitive potassium Kv2 channels as new targets for insecticides Acs Symposium Series. 1172: 71-81. DOI: 10.1021/bk-2014-1172.ch006 |
0.501 |
|
| 2013 |
Swale DR, Tong F, Temeyer KB, Li A, Lam PC, Totrov MM, Carlier PR, Pérez de León AA, Bloomquist JR. Inhibitor profile of bis(n)-tacrines and N-methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi. Pesticide Biochemistry and Physiology. 106. PMID 24187393 DOI: 10.1016/J.Pestbp.2013.03.005 |
0.719 |
|
| 2013 |
Tong F, Islam RM, Carlier PR, Ma M, Ekström F, Bloomquist JR. Effects of Anticholinesterases on Catalysis and Induced Conformational Change of the Peripheral Anionic Site of Murine Acetylcholinesterase. Pesticide Biochemistry and Physiology. 106: 79-84. PMID 24003261 DOI: 10.1016/J.Pestbp.2013.04.001 |
0.351 |
|
| 2013 |
Gao M, Patwardhan NN, Carlier PR. Stereochemical inversion of a cyano-stabilized grignard reagent: remarkable effects of the ethereal solvent structure and concentration. Journal of the American Chemical Society. 135: 14390-400. PMID 23978216 DOI: 10.1021/Ja407348S |
0.634 |
|
| 2013 |
Mutunga JM, Boina DR, Anderson TD, Bloomquist JR, Carlier PR, Wong DM, Lam PC, Totrov MM. Neurotoxicology of bis(n)-tacrines on Blattella germanica and Drosophila melanogaster acetylcholinesterase. Archives of Insect Biochemistry and Physiology. 83: 180-94. PMID 23740645 DOI: 10.1002/Arch.21104 |
0.707 |
|
| 2013 |
Wong DM, Li J, Lam PC, Hartsel JA, Mutunga JM, Totrov M, Bloomquist JR, Carlier PR. Aryl methylcarbamates: potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae. Chemico-Biological Interactions. 203: 314-8. PMID 22989775 DOI: 10.1016/J.Cbi.2012.09.001 |
0.711 |
|
| 2013 |
Jiang Y, Swale D, Carlier PR, Hartsel JA, Ma M, Ekström F, Bloomquist JR. Evaluation of novel carbamate insecticides for neurotoxicity to non-target species Pesticide Biochemistry and Physiology. 106: 156-161. DOI: 10.1016/J.Pestbp.2013.03.006 |
0.35 |
|
| 2012 |
Wong DM, Li J, Chen QH, Han Q, Mutunga JM, Wysinski A, Anderson TD, Ding H, Carpenetti TL, Verma A, Islam R, Paulson SL, Lam PC, Totrov M, Bloomquist JR, ... Carlier PR, et al. Select small core structure carbamates exhibit high contact toxicity to "carbamate-resistant" strain malaria mosquitoes, Anopheles gambiae (Akron). Plos One. 7: e46712. PMID 23049714 DOI: 10.1371/Journal.Pone.0046712 |
0.766 |
|
| 2012 |
Hartsel JA, Wong DM, Mutunga JM, Ma M, Anderson TD, Wysinski A, Islam R, Wong EA, Paulson SL, Li J, Lam PC, Totrov MM, Bloomquist JR, Carlier PR. Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. 22: 4593-8. PMID 22738634 DOI: 10.1016/J.Bmcl.2012.05.103 |
0.707 |
|
| 2011 |
Patwardhan NN, Gao M, Carlier PR. Incremental solvation precedes ion-pair separation in enantiomerization of a cyano-stabilized Grignard reagent. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 12250-3. PMID 21938750 DOI: 10.1002/Chem.201102253 |
0.589 |
|
| 2011 |
Monceaux CJ, Hirata-Fukae C, Lam PC, Totrov MM, Matsuoka Y, Carlier PR. Triazole-linked reduced amide isosteres: an approach for the fragment-based drug discovery of anti-Alzheimer's BACE1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 3992-6. PMID 21621412 DOI: 10.1016/J.Bmcl.2011.05.007 |
0.752 |
|
| 2011 |
Ma M, Mehta J, Williams LD, Carlier PR. Pd-catalyzed amination as an alternative to nucleophilic aromatic substitution for the synthesis of N-alkyltacrines and analogues. Tetrahedron Letters. 52: 916-919. PMID 21286231 DOI: 10.1016/J.Tetlet.2010.12.073 |
0.551 |
|
| 2010 |
Carlier PR, Sun YS, Hsu DC, Chen QH. Axial-selective H/D exchange of glycine-derived 1H-benzo[e][1,4]diazepin-2(3H)-ones: kinetic and computational studies of enantiomerization. The Journal of Organic Chemistry. 75: 6588-94. PMID 20828175 DOI: 10.1021/Jo1010608 |
0.64 |
|
| 2010 |
Deora N, Carlier PR. Computational studies of ion-pair separation of benzylic organolithium compounds in THF: importance of explicit and implicit solvation. The Journal of Organic Chemistry. 75: 1061-9. PMID 20102232 DOI: 10.1021/Jo9016452 |
0.761 |
|
| 2010 |
Monceaux CJ, Carlier PR. Regioselective synthesis of aniline-derived 1,3- and Ci-symmetric 1,4-diols from trans-1,4-cyclohexadiene dioxide. Organic Letters. 12: 620-3. PMID 20067254 DOI: 10.1021/Ol902856B |
0.764 |
|
| 2010 |
Carlier PR, Hsu DC, Bryson SA. Self-regeneration of stereocenters (SRS) via stereolabile axially chiral intermediates Topics in Stereochemistry. 26: 53-91. DOI: 10.1002/9783906390628.Ch2 |
0.601 |
|
| 2009 |
Hsu DC, Lam PC, Slebodnick C, Carlier PR. Complete mapping of the stereochemical course of retentive deprotonation/alkylation of 1H-benzo[e][1,4]diazepin-2(3H)-ones. Journal of the American Chemical Society. 131: 18168-76. PMID 19921816 DOI: 10.1021/Ja907507J |
0.78 |
|
| 2008 |
Liang Y, Shaw AM, Boules M, Briody S, Robinson J, Oliveros A, Blazar E, Williams K, Zhang Y, Carlier PR, Richelson E. Antidepressant-like pharmacological profile of a novel triple reuptake inhibitor, (1S,2S)-3-(methylamino)-2-(naphthalen-2-yl)-1-phenylpropan-1-ol (PRC200-SS). The Journal of Pharmacology and Experimental Therapeutics. 327: 573-83. PMID 18689611 DOI: 10.1124/Jpet.108.143610 |
0.492 |
|
| 2008 |
Carlier PR, Anderson TD, Wong DM, Hsu DC, Hartsel J, Ma M, Wong EA, Choudhury R, Lam PC, Totrov MM, Bloomquist JR. Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae. Chemico-Biological Interactions. 175: 368-75. PMID 18554580 DOI: 10.1016/J.Cbi.2008.04.037 |
0.772 |
|
| 2007 |
Li WM, Kan KK, Carlier PR, Pang YP, Han YF. East meets West in the search for Alzheimer's therapeutics - novel dimeric inhibitors from tacrine and huperzine A. Current Alzheimer Research. 4: 386-96. PMID 17908041 DOI: 10.2174/156720507781788918 |
0.332 |
|
| 2007 |
Carlier PR, Zhang Y. The first enantioenriched metalated nitrile possessing macroscopic configurational stability. Organic Letters. 9: 1319-22. PMID 17348666 DOI: 10.1021/Ol070149G |
0.489 |
|
| 2007 |
Shaw AM, Boules M, Zhang Y, Williams K, Robinson J, Carlier PR, Richelson E. Antidepressant-like effects of novel triple reuptake inhibitors, PRC025 and PRC050. European Journal of Pharmacology. 555: 30-6. PMID 17109850 DOI: 10.1016/J.Ejphar.2006.10.004 |
0.517 |
|
| 2007 |
Li C, Carlier PR, Ren H, Kan KK, Hui K, Wang H, Li W, Li Z, Xiong K, Clement EC, Xue H, Liu X, Li M, Pang Y, Han Y. Alkylene tether-length dependent gamma-aminobutyric acid type A receptor competitive antagonism by tacrine dimers. Neuropharmacology. 52: 436-43. PMID 17056074 DOI: 10.1016/J.Neuropharm.2006.07.039 |
0.74 |
|
| 2006 |
Carlier PR, Zhao H, MacQuarrie-Hunter SL, DeGuzman JC, Hsu DC. Enantioselective synthesis of diversely substituted quaternary 1,4-benzodiazepin-2-ones and 1,4-benzodiazepine-2,5-diones. Journal of the American Chemical Society. 128: 15215-20. PMID 17117873 DOI: 10.1021/Ja0640142 |
0.769 |
|
| 2006 |
Carlier PR, Zhang Y, Slebodnick C, Lo MM, Williams ID. Effect of 2,6-disubstituted aryl groups on acyclic conformation: preference for an antiperiplanar orientation of the geminal and vicinal hydrogens. The Journal of Organic Chemistry. 71: 8835-41. PMID 17081013 DOI: 10.1021/Jo061495Z |
0.455 |
|
| 2006 |
Rydberg EH, Brumshtein B, Greenblatt HM, Wong DM, Shaya D, Williams LD, Carlier PR, Pang YP, Silman I, Sussman JL. Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge. Journal of Medicinal Chemistry. 49: 5491-500. PMID 16942022 DOI: 10.1021/Jm060164B |
0.587 |
|
| 2006 |
Carlier PR, Deora N, Crawford TD. Protonated 2-methyl-1,2-epoxypropane: A challenging problem for density functional theory Journal of Organic Chemistry. 71: 1592-1597. PMID 16468811 DOI: 10.1021/Jo052303N |
0.76 |
|
| 2005 |
Haviv H, Wong DM, Greenblatt HM, Carlier PR, Pang YP, Silman I, Sussman JL. Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase Journal of the American Chemical Society. 127: 11029-11036. PMID 16076210 DOI: 10.1021/Ja051765F |
0.326 |
|
| 2005 |
Lam PC, Carlier PR. Experimental and computational studies of ring inversion of 1,4-benzodiazepin-2-ones: implications for memory of chirality transformations. The Journal of Organic Chemistry. 70: 1530-8. PMID 15730270 DOI: 10.1021/Jo048450N |
0.701 |
|
| 2005 |
Zhao H, Hsu DC, Carlier PR. Memory of chirality: An emerging strategy for asymmetric synthesis Synthesis. 1-16. DOI: 10.1055/S-2004-834931 |
0.653 |
|
| 2005 |
Clement EC, Carlier PR. A simple route to tetrahydro-1,4-benzodiazepin-3-ones bearing diverse N1, N4, and C10 functionalization Tetrahedron Letters. 46: 3633-3635. DOI: 10.1016/J.Tetlet.2005.03.171 |
0.764 |
|
| 2005 |
Carlier PR, Lam PCH, DeGuzman JC, Zhao H. Memory of chirality trapping of low inversion barrier 1,4-benzodiazepin-2- one enolates Tetrahedron Asymmetry. 16: 2998-3002. DOI: 10.1016/J.Tetasy.2005.08.017 |
0.767 |
|
| 2004 |
Du DM, Carlier PR. Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease. Current Pharmaceutical Design. 10: 3141-56. PMID 15544504 DOI: 10.2174/1381612043383412 |
0.318 |
|
| 2003 |
Carlier PR, Zhao H, DeGuzman J, Lam PC. Enantioselective synthesis of "quaternary" 1,4-benzodiazepin-2-one scaffolds via memory of chirality. Journal of the American Chemical Society. 125: 11482-3. PMID 13129335 DOI: 10.1021/Ja0365781 |
0.756 |
|
| 2003 |
Carlier PR. Configurational stability of chiral lithiated cyclopropylnitriles: a density functional study. Chirality. 15: 340-7. PMID 12666242 DOI: 10.1002/Chir.10222 |
0.389 |
|
| 2003 |
Wong DM, Greenblatt HM, Dvir H, Carlier PR, Han YF, Pang YP, Silman I, Sussman JL. Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity. Journal of the American Chemical Society. 125: 363-73. PMID 12517147 DOI: 10.1021/Ja021111W |
0.348 |
|
| 2002 |
Lewis WG, Green LG, Grynszpan F, Radi? Z, Carlier PR, Taylor P, Finn MG, Sharpless KB. Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks. Angewandte Chemie (International Ed. in English). 41: 1053-7. PMID 12491310 DOI: 10.1002/1521-3773(20020315)41:6<1053::Aid-Anie1053>3.0.Co;2-4 |
0.592 |
|
| 2002 |
Carlier PR, Lam PC, Wong DM. Catalytic asymmetric synthesis of protected tryptophan regioisomers. The Journal of Organic Chemistry. 67: 6256-9. PMID 12182675 DOI: 10.1021/jo025964i |
0.67 |
|
| 2002 |
Carlier PR, Madura JD. Effective computational modeling of constitutional isomerism and aggregation states of explicit solvates of lithiated phenylacetonitrile. The Journal of Organic Chemistry. 67: 3832-40. PMID 12027700 DOI: 10.1021/Jo0255633 |
0.309 |
|
| 2002 |
Lewis WG, Green LG, Grynszpan F, Radić Z, Carlier PR, Taylor P, Finn MG, Sharpless KB. Cover Picture: Angew. Chem. Int. Ed. 6/2002 Angewandte Chemie International Edition. 41: 875-875. DOI: 10.1002/1521-3773(20020315)41:6<875::Aid-Anie875>3.0.Co;2-Y |
0.598 |
|
| 2002 |
Lewis WG, Green LG, Grynszpan F, Radić Z, Carlier PR, Taylor P, Finn MG, Sharpless KB. Titelbild: 6/2002 Angewandte Chemie. 114: 915-915. DOI: 10.1002/1521-3757(20020315)114:6<915::Aid-Ange915>3.0.Co;2-3 |
0.574 |
|
| 2000 |
Carlier PR, Lo CW, Lo MM, Wan NC, Williams ID. HMPA promotes retro-aldol reaction, resulting in syn-selective addition of lithiated 1-naphthylacetonitrile to aromatic aldehydes Organic Letters. 2: 2443-5. PMID 10956517 DOI: 10.1021/Ol006099W |
0.342 |
|
| 1999 |
Han YF, Li CP, Chow E, Wang H, Pang YP, Carlier PR. Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities. Bioorganic & Medicinal Chemistry. 7: 2569-75. PMID 10632067 DOI: 10.1016/S0968-0896(99)00178-9 |
0.366 |
|
| 1999 |
Carlier PR, Chow ES, Han Y, Liu J, El Yazal J, Pang YP. Heterodimeric tacrine-based acetylcholinesterase inhibitors: investigating ligand-peripheral site interactions. Journal of Medicinal Chemistry. 42: 4225-31. PMID 10514292 DOI: 10.1021/Jm990224W |
0.319 |
|
| 1999 |
Carlier PR, Du DM, Han Y, Liu J, Pang YP. Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors. Bioorganic & Medicinal Chemistry Letters. 9: 2335-8. PMID 10476864 DOI: 10.1016/S0960-894X(99)00396-0 |
0.356 |
|
| 1999 |
Carlier PR, Han YF, Chow ES, Li CP, Wang H, Lieu TX, Wong HS, Pang YP. Evaluation of short-tether bis-THA AChE inhibitors. A further test of the dual binding site hypothesis. Bioorganic & Medicinal Chemistry. 7: 351-7. PMID 10218828 DOI: 10.1016/S0968-0896(98)00213-2 |
0.36 |
|
| 1999 |
Li CY, Wang H, Xue H, Carlier PR, Hui KM, Pang YP, Li ZW, Han YF. Bis(7)-tacrine, a novel dimeric AChE inhibitor, is a potent GABA(A) receptor antagonist. Neuroreport. 10: 795-800. PMID 10208550 DOI: 10.1097/00001756-199903170-00024 |
0.304 |
|
| 1999 |
Wang H, Carlier PR, Ho WL, Wu DC, Lee NT, Li CP, Pang YP, Han YF. Effects of bis(7)-tacrine, a novel anti-Alzheimer's agent, on rat brain AChE. Neuroreport. 10: 789-93. PMID 10208549 DOI: 10.1097/00001756-199903170-00023 |
0.328 |
|
| 1998 |
Carlier PR, Lo MM, Lo PC, Richelson E, Tatsumi M, Reynolds IJ, Sharma TA. Synthesis of a potent wide-spectrum serotonin-, norepinephrine-, dopamine-reuptake inhibitor (SNDRI) and a species-selective dopamine-reuptake inhibitor based on the gamma-amino alcohol functional group. Bioorganic & Medicinal Chemistry Letters. 8: 487-92. PMID 9871604 DOI: 10.1016/S0960-894X(98)00062-6 |
0.321 |
|
| 1997 |
Carlier PR, Lo KM, Lo MMC, Lo PCK, Lo CWS. Synthetic Optimization and Structural Limitations of the Nitrile Aldol Reaction Journal of Organic Chemistry. 62: 6316-6321. DOI: 10.1021/Jo9702148 |
0.317 |
|
| 1995 |
Carlier PR, Lo KM, Lo MM, Williams ID. Anti-Selective Aldol Reaction of Benzylic Nitriles and Synthesis of .gamma.-Amino Alcohols The Journal of Organic Chemistry. 60: 7511-7517. DOI: 10.1021/Jo00128A025 |
0.301 |
|
| 1994 |
Carlier PR, Lo KM. 2,3-Anti selective aldol reaction of phenylacetonitrile Journal of Organic Chemistry. 59: 4053-4055. DOI: 10.1021/Jo00094A011 |
0.336 |
|
| 1989 |
Carlier PR, Sharpless KB. Studies on the mechanism of the asymmetric epoxidation: a ligand variation approach The Journal of Organic Chemistry. 54: 4016-4018. DOI: 10.1021/Jo00278A004 |
0.429 |
|
| 1988 |
Caron M, Carlier PR, Sharpless KB. Regioselective azide opening of 2,3-epoxy alcohols by [Ti(O-i-Pr)2(N3)2]: synthesis of .alpha.-amino acids The Journal of Organic Chemistry. 53: 5185-5187. DOI: 10.1021/Jo00256A063 |
0.457 |
|
| 1988 |
Carlier PR, Mungall WS, Schroder G, Sharpless KB. Enhanced kinetic resolution and enzyme-like shape selectivity Journal of the American Chemical Society. 110: 2978-2979. DOI: 10.1021/Ja00217A052 |
0.456 |
|
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