Year |
Citation |
Score |
2018 |
Elgarf AA, Siebert DCB, Steudle F, Draxler A, Li G, Huang S, Cook JM, Ernst M, Scholze P. Different Benzodiazepines Bind with Distinct Binding Modes to GABA Receptors. Acs Chemical Biology. PMID 29767950 DOI: 10.1021/Acschembio.8B00144 |
0.736 |
|
2013 |
Varagic Z, Ramerstorfer J, Huang S, Rallapalli S, Sarto-Jackson I, Cook J, Sieghart W, Ernst M. Subtype selectivity of α+β- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors. British Journal of Pharmacology. 169: 384-99. PMID 23472935 DOI: 10.1111/Bph.12153 |
0.78 |
|
2013 |
Varagic Z, Wimmer L, Schnürch M, Mihovilovic MD, Huang S, Rallapalli S, Cook JM, Mirheydari P, Ecker GF, Sieghart W, Ernst M. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. British Journal of Pharmacology. 169: 371-83. PMID 23472852 DOI: 10.1111/Bph.12151 |
0.77 |
|
2013 |
Drexler B, Zinser S, Huang S, Poe MM, Rudolph U, Cook JM, Antkowiak B. Enhancing the function of alpha5-subunit-containing GABAA receptors promotes action potential firing of neocortical neurons during up-states. European Journal of Pharmacology. 703: 18-24. PMID 23380687 DOI: 10.1016/J.Ejphar.2013.01.034 |
0.735 |
|
2012 |
Vinkers CH, Hendriksen H, van Oorschot R, Cook JM, Rallipalli S, Huang S, Millan MJ, Olivier B, Groenink L. Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes. Psychopharmacology. 219: 897-908. PMID 21833506 DOI: 10.1007/S00213-011-2423-0 |
0.641 |
|
2010 |
Fischer BD, Licata SC, Edwankar RV, Wang ZJ, Huang S, He X, Yu J, Zhou H, Johnson EM, Cook JM, Furtmüller R, Ramerstorfer J, Sieghart W, Roth BL, Majumder S, et al. Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure. Neuropharmacology. 59: 612-8. PMID 20727364 DOI: 10.1016/J.Neuropharm.2010.08.011 |
0.725 |
|
2010 |
Savić MM, Majumder S, Huang S, Edwankar RV, Furtmüller R, Joksimović S, Clayton T, Ramerstorfer J, Milinković MM, Roth BL, Sieghart W, Cook JM. Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats? Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 376-86. PMID 20074611 DOI: 10.1016/J.Pnpbp.2010.01.004 |
0.76 |
|
2009 |
Rivas FM, Stables JP, Murphree L, Edwankar RV, Edwankar CR, Huang S, Jain HD, Zhou H, Majumder S, Sankar S, Roth BL, Ramerstorfer J, Furtmüller R, Sieghart W, Cook JM. Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models. Journal of Medicinal Chemistry. 52: 1795-8. PMID 19275170 DOI: 10.1021/Jm801652D |
0.636 |
|
2008 |
Savić MM, Huang S, Furtmüller R, Clayton T, Huck S, Obradović DI, Ugresić ND, Sieghart W, Bokonjić DR, Cook JM. Are GABAA receptors containing alpha5 subunits contributing to the sedative properties of benzodiazepine site agonists? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 332-9. PMID 17392731 DOI: 10.1038/Sj.Npp.1301403 |
0.621 |
|
2007 |
Liao X, Huang S, Zhou H, Parrish D, Cook JM. Cascade approach toward the core structure of neosarpagine. Organic Letters. 9: 1469-71. PMID 17358071 DOI: 10.1021/Ol070148O |
0.491 |
|
2007 |
Han D, Försterling FH, Deschamps JR, Parrish D, Liu X, Yin W, Huang S, Cook JM. Conformational analysis of the cis- and trans-adducts of the Pictet - Spengler reaction. Evidence for the structural basis for the C(1) - N(2) scission process in the cis- to trans-isomerization. Journal of Natural Products. 70: 75-82. PMID 17253853 DOI: 10.1021/Np060391G |
0.647 |
|
2006 |
Duke AN, Platt DM, Cook JM, Huang S, Yin W, Mattingly BA, Rowlett JK. Enhanced sucrose pellet consumption induced by benzodiazepine-type drugs in squirrel monkeys: role of GABAA receptor subtypes. Psychopharmacology. 187: 321-30. PMID 16783540 DOI: 10.1007/S00213-006-0431-2 |
0.679 |
|
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