Year |
Citation |
Score |
2018 |
Skepper CK, Moreau RJ, Appleton BA, Benton BM, Drumm JE, Feng BY, Geng M, Lingel A, Lu Y, Mamo M, Mergo W, Mostafavi M, Rath CM, Steffek M, Takeoka KT, et al. Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity. Journal of Medicinal Chemistry. PMID 29551072 DOI: 10.1021/Acs.Jmedchem.7B01861 |
0.314 |
|
2018 |
Moreau RJ, Skepper CK, Appleton BA, Blechschmidt A, Balibar CJ, Benton BM, Drumm JE, Feng BY, Geng M, Li C, Lindvall MK, Lingel A, Lu Y, Mamo M, Mergo W, et al. Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria. Journal of Medicinal Chemistry. PMID 29498517 DOI: 10.1021/Acs.Jmedchem.7B01691 |
0.33 |
|
2017 |
Rath CM, Benton BM, De Vicente J, Drumm JE, Geng M, Li C, Moreau RJ, Shen X, Skepper CK, Steffek M, Takeoka K, Wang L, Wei JR, Xu W, Zhang Q, ... Feng BY, et al. Optimization of CoaD inhibitors against Gram-negative organisms through targeted metabolomics. Acs Infectious Diseases. PMID 29243909 DOI: 10.1021/Acsinfecdis.7B00214 |
0.408 |
|
2008 |
Babaoglu K, Simeonov A, Irwin JJ, Nelson ME, Feng B, Thomas CJ, Cancian L, Costi MP, Maltby DA, Jadhav A, Inglese J, Austin CP, Shoichet BK. Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. Journal of Medicinal Chemistry. 51: 2502-11. PMID 18333608 DOI: 10.1021/Jm701500E |
0.644 |
|
2008 |
Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. Small-molecule aggregates inhibit amyloid polymerization. Nature Chemical Biology. 4: 197-9. PMID 18223646 DOI: 10.1038/Nchembio.65 |
0.638 |
|
2007 |
Feng BY, Simeonov A, Jadhav A, Babaoglu K, Inglese J, Shoichet BK, Austin CP. A high-throughput screen for aggregation-based inhibition in a large compound library. Journal of Medicinal Chemistry. 50: 2385-90. PMID 17447748 DOI: 10.1021/Jm061317Y |
0.7 |
|
2007 |
Shoichet BK, Feng BY, Coan KED. Shadows on screens Rsc Biomolecular Sciences. 223-241. |
0.507 |
|
2006 |
Feng BY, Shoichet BK. A detergent-based assay for the detection of promiscuous inhibitors. Nature Protocols. 1: 550-3. PMID 17191086 DOI: 10.1038/Nprot.2006.77 |
0.678 |
|
2006 |
Feng BY, Shoichet BK. Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures. Journal of Medicinal Chemistry. 49: 2151-4. PMID 16570910 DOI: 10.1021/Jm060029Z |
0.67 |
|
2005 |
Feng BY, Shelat A, Doman TN, Guy RK, Shoichet BK. High-throughput assays for promiscuous inhibitors. Nature Chemical Biology. 1: 146-8. PMID 16408018 DOI: 10.1038/Nchembio718 |
0.631 |
|
2003 |
McGovern SL, Helfand BT, Feng B, Shoichet BK. A specific mechanism of nonspecific inhibition. Journal of Medicinal Chemistry. 46: 4265-72. PMID 13678405 DOI: 10.1021/Jm030266R |
0.623 |
|
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