Year |
Citation |
Score |
2021 |
Nair RM, Seenivasan A, Liu B, Chen D, Lowe ED, Lorenz S. Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe. Acs Chemical Biology. PMID 34403242 DOI: 10.1021/acschembio.1c00433 |
0.332 |
|
2020 |
Liess AKL, Kucerova A, Schweimer K, Schlesinger D, Dybkov O, Urlaub H, Mansfeld J, Lorenz S. Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Science Signaling. 13. PMID 33082289 DOI: 10.1126/scisignal.aba8208 |
0.348 |
|
2020 |
Ries LK, Liess AK, Feiler CG, Spratt DE, Lowe E, Lorenz S. Crystal structure of the catalytic C-lobe of the HECT-type ubiquitin ligase E6AP. Protein Science : a Publication of the Protein Society. PMID 31994269 DOI: 10.1002/Pro.3832 |
0.383 |
|
2019 |
Deol KK, Lorenz S, Strieter ER. Enzymatic Logic of Ubiquitin Chain Assembly. Frontiers in Physiology. 10: 835. PMID 31333493 DOI: 10.3389/Fphys.2019.00835 |
0.405 |
|
2019 |
Liess AKL, Kucerova A, Schweimer K, Yu L, Roumeliotis TI, Diebold M, Dybkov O, Sotriffer C, Urlaub H, Choudhary JS, Mansfeld J, Lorenz S. Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure (London, England : 1993). PMID 31230944 DOI: 10.2210/Pdb6Qh3/Pdb |
0.454 |
|
2019 |
Ries LK, Sander B, Deol KK, Letzelter MA, Strieter ER, Lorenz S. Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity. The Journal of Biological Chemistry. PMID 30737286 DOI: 10.1074/Jbc.Ra118.007014 |
0.434 |
|
2018 |
Chen D, Gehringer M, Lorenz S. Developing small-molecule inhibitors of HECT-type ubiquitin ligases for therapeutic applications: challenges and opportunities. Chembiochem : a European Journal of Chemical Biology. PMID 30088849 DOI: 10.1002/Cbic.201800321 |
0.357 |
|
2017 |
Lorenz S. Structural mechanisms of HECT-type ubiquitin ligases. Biological Chemistry. PMID 29016349 DOI: 10.1515/Hsz-2017-0184 |
0.442 |
|
2017 |
Sander B, Xu W, Eilers M, Popov N, Lorenz S. A conformational switch regulates the ubiquitin ligase HUWE1. Elife. 6. PMID 28193319 DOI: 10.7554/Elife.21036 |
0.386 |
|
2016 |
Lorenz S, Bhattacharyya M, Feiler C, Rape M, Kuriyan J. Crystal Structure of a Ube2S-Ubiquitin Conjugate. Plos One. 11: e0147550. PMID 26828794 DOI: 10.1371/Journal.Pone.0147550 |
0.554 |
|
2016 |
Ries L, Lorenz S. Ubiquitin-Ligasen: heiße Targets für die Wirkstoffentwicklung? Biospektrum. 22: 244-246. DOI: 10.1007/S12268-016-0679-Y |
0.304 |
|
2015 |
Lorenz S, Deng P, Hantschel O, Superti-Furga G, Kuriyan J. Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity. The Biochemical Journal. 468: 283-91. PMID 25779001 DOI: 10.1042/Bj20141492 |
0.458 |
|
2013 |
Lorenz S, Cantor AJ, Rape M, Kuriyan J. Macromolecular juggling by ubiquitylation enzymes. Bmc Biology. 11: 65. PMID 23800009 DOI: 10.1186/1741-7007-11-65 |
0.544 |
|
2011 |
Wickliffe KE, Lorenz S, Wemmer DE, Kuriyan J, Rape M. The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2. Cell. 144: 769-81. PMID 21376237 DOI: 10.1016/J.Cell.2011.01.035 |
0.559 |
|
2008 |
Lorenz S, Vakonakis I, Lowe ED, Campbell ID, Noble ME, Hoellerer MK. Structural analysis of the interactions between paxillin LD motifs and alpha-parvin. Structure (London, England : 1993). 16: 1521-31. PMID 18940607 DOI: 10.1016/J.Str.2008.08.007 |
0.532 |
|
2002 |
Spudich G, Lorenz S, Marqusee S. Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state. Protein Science : a Publication of the Protein Society. 11: 522-8. PMID 11847275 DOI: 10.1110/Ps.37202 |
0.306 |
|
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