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Nathalie Saurat, Ph.D B.Sc - Publications

Affiliations: 
2010-2014 Gurdon Institute University of Cambridge, Cambridge, England, United Kingdom 
 2015- Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
Area:
Stem Cells, Neuroscience, Neurodegeneration, Aging, Disease Modelling

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Saurat N, Minotti AP, Rahman MT, Sikder T, Zhang C, Cornacchia D, Jungverdorben J, Ciceri G, Betel D, Studer L. Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration. Cell Stem Cell. PMID 38917806 DOI: 10.1016/j.stem.2024.06.001  0.637
2024 Kim TW, Koo SY, Riessland M, Chaudhry F, Kolisnyk B, Cho HS, Russo MV, Saurat N, Mehta S, Garippa R, Betel D, Studer L. TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons. Cell. PMID 38866017 DOI: 10.1016/j.cell.2024.05.030  0.754
2024 Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, et al. Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. Biorxiv : the Preprint Server For Biology. PMID 38496508 DOI: 10.1101/2024.03.03.583145  0.569
2023 Zhang C, Saurat N, Cornacchia D, Chung SY, Skider T, Minotti A, Studer L, Betel D. Establishing RNAge to score cellular aging and rejuvenation paradigms and identify novel age-modulating compounds. Biorxiv : the Preprint Server For Biology. PMID 37461485 DOI: 10.1101/2023.07.03.547539  0.505
2023 Kim TW, Koo SY, Riessland M, Cho H, Chaudhry F, Kolisnyk B, Russo MV, Saurat N, Mehta S, Garippa R, Betel D, Studer L. TNF-NFkB-p53 axis restricts survival of hPSC-derived dopamine neuron. Biorxiv : the Preprint Server For Biology. PMID 37034664 DOI: 10.1101/2023.03.29.534819  0.759
2021 Baggiolini A, Callahan SJ, Montal E, Weiss JM, Trieu T, Tagore MM, Tischfield SE, Walsh RM, Suresh S, Fan Y, Campbell NR, Perlee SC, Saurat N, Hunter MV, Simon-Vermot T, et al. Developmental chromatin programs determine oncogenic competence in melanoma. Science (New York, N.Y.). 373: eabc1048. PMID 34516843 DOI: 10.1126/science.abc1048  0.384
2021 Guttikonda SR, Sikkema L, Tchieu J, Saurat N, Walsh RM, Harschnitz O, Ciceri G, Sneeboer M, Mazutis L, Setty M, Zumbo P, Betel D, de Witte LD, Pe'er D, Studer L. Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease. Nature Neuroscience. PMID 33558694 DOI: 10.1038/s41593-020-00796-z  0.572
2018 Kishinevsky S, Wang T, Rodina A, Chung SY, Xu C, Philip J, Taldone T, Joshi S, Alpaugh ML, Bolaender A, Gutbier S, Sandhu D, Fattahi F, Zimmer B, Shah SK, ... ... Saurat NG, et al. HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons. Nature Communications. 9: 4345. PMID 30341316 DOI: 10.1038/S41467-018-06486-6  0.724
2016 Zeltner N, Fattahi F, Dubois NC, Saurat N, Lafaille F, Shang L, Zimmer B, Tchieu J, Soliman MA, Lee G, Casanova JL, Studer L. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nature Medicine. PMID 27841875 DOI: 10.1038/Nm.4220  0.639
2016 Saurat NG, Livesey FJ, Moore S. Cortical Differentiation of Human Pluripotent Cells for In Vitro Modeling of Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 1303: 267-78. PMID 26235073 DOI: 10.1007/978-1-4939-2627-5_16  0.688
2016 Saurat NG, Livesey FJ, Moore S. Cortical differentiation of human pluripotent cells for in vitro modeling of Alzheimer’s disease Methods in Molecular Biology. 1303: 267-278. DOI: 10.1007/978-1-4939-2627-5_16  0.616
2015 Moore S, Evans LD, Andersson T, Portelius E, Smith J, Dias TB, Saurat N, McGlade A, Kirwan P, Blennow K, Hardy J, Zetterberg H, Livesey FJ. APP metabolism regulates tau proteostasis in human cerebral cortex neurons. Cell Reports. 11: 689-96. PMID 25921538 DOI: 10.1016/J.Celrep.2015.03.068  0.706
2015 Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, et al. G&T-seq: parallel sequencing of single-cell genomes and transcriptomes. Nature Methods. 12: 519-22. PMID 25915121 DOI: 10.1038/Nmeth.3370  0.562
2013 Saurat N, Andersson T, Vasistha NA, Molnár Z, Livesey FJ. Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Neural Development. 8: 14. PMID 23895693 DOI: 10.1186/1749-8104-8-14  0.673
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