Karen Gale - Related publications

Georgetown University, Washington, DC 
neuropharmacology, epilepsy
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Leclercq K, Matagne A, Provins L, Klitgaard H, Kaminski RM. Pharmacological profile of the antiepileptic drug candidate padsevonil - characterization in rodent seizure and epilepsy models. The Journal of Pharmacology and Experimental Therapeutics. PMID 31619464 DOI: 10.1124/jpet.119.261222   
2019 Lertwittayanon W, Devinsky O, Carlen PL. Cardiorespiratory depression from brainstem seizure activity in freely moving rats. Neurobiology of Disease. 104628. PMID 31669732 DOI: 10.1016/j.nbd.2019.104628   
2019 Bortel A, Yao ZS, Shmuel A. A rat model of somatosensory-evoked reflex seizures induced by peripheral stimulation. Epilepsy Research. 157: 106209. PMID 31629247 DOI: 10.1016/j.eplepsyres.2019.106209   
2019 Cela E, Sjöström PJ. Novel Optogenetic Approaches in Epilepsy Research. Frontiers in Neuroscience. 13: 947. PMID 31551699 DOI: 10.3389/fnins.2019.00947   
2019 Gericke B, Brandt C, Theilmann W, Welzel L, Schidlitzki A, Twele F, Kaczmarek E, Anjum M, Hillmann P, Löscher W. Selective inhibition of mTORC1/2 or PI3K/mTORC1/2 signaling does not prevent or modify epilepsy in the intrahippocampal kainate mouse model. Neuropharmacology. 162: 107817. PMID 31654704 DOI: 10.1016/j.neuropharm.2019.107817   
2019 Schulze-Bonhage A, Böttcher S, Glasstetter M, Epitashvili N, Bruno E, Richardson M, V Laerhoven K, Dümpelmann M. [Mobile seizure monitoring in epilepsy patients]. Der Nervenarzt. PMID 31673723 DOI: 10.1007/s00115-019-00822-x   
2019 Kundap UP, Choo BKM, Kumari Y, Ahmed N, Othman IB, Shaikh MF. Embelin Protects Against Acute Pentylenetetrazole-Induced Seizures and Positively Modulates Cognitive Function in Adult Zebrafish. Frontiers in Pharmacology. 10: 1249. PMID 31708779 DOI: 10.3389/fphar.2019.01249   
2019 Jansen NA, Schenke M, Voskuyl RA, Thijs RD, van den Maagdenberg AMJM, Tolner EA. Apnea associated with brainstem seizures in mice is caused by medullary spreading depolarization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31628185 DOI: 10.1523/JNEUROSCI.1713-19.2019   
2019 Melin E, Nanobashvili A, Avdic U, Gøtzsche CR, Andersson M, Woldbye DPD, Kokaia M. Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy. Molecular Therapy. Methods & Clinical Development. 15: 179-193. PMID 31660420 DOI: 10.1016/j.omtm.2019.09.004   
2019 Cavarec F, Krauss P, Witkowski T, Broisat A, Ghezzi C, De Gois S, Giros B, Depaulis A, Deransart C. Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis. Epilepsia. PMID 31535376 DOI: 10.1111/epi.16342   
2019 Roggenhofer E, Santarnecchi E, Muller S, Kherif F, Wiest R, Seeck M, Draganski B. Trajectories of brain remodeling in temporal lobe epilepsy. Journal of Neurology. PMID 31549200 DOI: 10.1007/s00415-019-09546-z   
2019 Chen NN, Zhao DJ, Sun YX, Wang DD, Ni H. Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus. Frontiers in Neuroscience. 13: 920. PMID 31551684 DOI: 10.3389/fnins.2019.00920   
2019 Martins R, Coelho J, Dos Santos TP, Moreno T, Quintas S, Levy A. Neurodevelopmental outcome predictors of term newborns with neonatal seizures. Revista De Neurologia. 69: 370-376. PMID 31657449 DOI: 10.33588/rn.6909.2019209   
2019 Yang X, Hei C, Liu P, Li PA. Prevention of post-ischemic seizure by rapamycin is associated with deactivation of mTOR and ERK1/2 pathways in hyperglycemic rats. Biochemical and Biophysical Research Communications. PMID 31564412 DOI: 10.1016/j.bbrc.2019.09.096   
2019 Gupta K, Schnell E. Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy. Plos One. 14: e0215789. PMID 31596871 DOI: 10.1371/journal.pone.0215789   
2019 Easton-Jones C, Woolard K, Mohr FC, Roy MA, Aleman M. Ganglioglioma of the Right Cerebrothalamus in a 7-Year-Old Quarter Horse Cross Gelding. Frontiers in Veterinary Science. 6: 356. PMID 31696122 DOI: 10.3389/fvets.2019.00356   
2019 Mo M, Eyo UB, Xie M, Peng J, Bosco DB, Umpierre AD, Zhu X, Tian DS, Xu P, Wu LJ. Microglial P2Y12 receptors regulate seizure-induced neurogenesis and immature neuronal projections. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31597724 DOI: 10.1523/JNEUROSCI.0487-19.2019   
2019 Zelano J, Axelsson M, Constantinescu R, Malmeström C, Kumlien E. Neuronal antibodies in adult patients with new-onset seizures: A prospective study. Brain and Behavior. e01442. PMID 31588654 DOI: 10.1002/brb3.1442   
2019 Zelano J, Axelsson M, Constantinescu R, Malmeström C, Kumlien E. Neuronal antibodies in adult patients with new-onset seizures: A prospective study. Brain and Behavior. e01442. PMID 31588654 DOI: 10.1002/brb3.1442   
2019 J E Vajda F, O Brien TJ, Graham JE, Hitchcock AA, Lander CM, Eadie MJ. Seizures in infancy in the offspring of women with epilepsy. Acta Neurologica Scandinavica. PMID 31532859 DOI: 10.1111/ane.13170   
2019 Abraira L, Giannini N, Santamarina E, Cazorla S, Bustamante A, Quintana M, Toledo M, Grau-López L, Jiménez M, Ciurans J, Becerra JL, Millán M, Cardona P, Terceño M, Zaragoza J, et al. Correlation of blood biomarkers with early-onset seizures after an acute stroke event. Epilepsy & Behavior : E&B. 106549. PMID 31677998 DOI: 10.1016/j.yebeh.2019.106549   
2019 Xiong W, Lu L, Chen J, Xiao Y, Zhou D. Chronic post-encephalitic epilepsy following Japanese encephalitis: Clinical features, neuroimaging data, and outcomes. Seizure. 72: 49-53. PMID 31600677 DOI: 10.1016/j.seizure.2019.09.010   
2019 Dechandt CRP, Ferrari GD, Dos Santos JR, de Oliveira JAC, da Silva-Jr RMP, Cunha AOS, Garcia-Cairasco N, Alberici LC. Energy Metabolism and Redox State in Brains of Wistar Audiogenic Rats, a Genetic Model of Epilepsy. Frontiers in Neurology. 10: 1007. PMID 31632331 DOI: 10.3389/fneur.2019.01007   
2019 González MI. Calpain-dependent cleavage of GABAergic proteins during epileptogenesis. Epilepsy Research. 157: 106206. PMID 31585309 DOI: 10.1016/j.eplepsyres.2019.106206   
2019 Lu XM, Browning J, Liao Z, Cao Y, Yang W, Shear DA. Post-Traumatic Epilepsy and Seizure Susceptibility in Rat Models of Penetrating and Closed-Head Brain Injury. Journal of Neurotrauma. PMID 31530242 DOI: 10.1089/neu.2019.6573   
2019 Kurtom W, Courchia B, Pensirikul A, Sosenko I, Del-Moral T. Lack of response to treatment with levetiracetam in extreme preterm infants with seizures. Journal of Perinatology : Official Journal of the California Perinatal Association. PMID 31548579 DOI: 10.1038/s41372-019-0498-3   
2019 Balashova A, Pershin V, Zaborskaya O, Tkachenko N, Mironov A, Guryev E, Kurbatov L, Gainullin M, Mukhina I. Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix Can Induce Seizures in Neonatal Mice. Frontiers in Neuroscience. 13: 1033. PMID 31632233 DOI: 10.3389/fnins.2019.01033   
2019 Altman K, Shavit-Stein E, Maggio N. Post Stroke Seizures and Epilepsy: From Proteases to Maladaptive Plasticity. Frontiers in Cellular Neuroscience. 13: 397. PMID 31607864 DOI: 10.3389/fncel.2019.00397   
2019 Wang X, Li T. Role of Adenosine Kinase Inhibitor in Adenosine Augmentation Therapy for Epilepsy: A potential novel drug for epilepsy. Current Drug Targets. PMID 31633474 DOI: 10.2174/1389450119666191014104347   
2019 Auer T, Schreppel P, Erker T, Schwarzer C. Impaired chloride homeostasis in epilepsy: Molecular basis, impact on treatment, and current treatment approaches. Pharmacology & Therapeutics. 107422. PMID 31626872 DOI: 10.1016/j.pharmthera.2019.107422   
2019 Gamkrelidze GN, Nanobashvili ZI, Bilanishvili IG, Lordkipanidze T, Kandashvili M, Kokaia M, Solomonia RO. Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo. Neuroreport. 30: 1129-1134. PMID 31568207 DOI: 10.1097/WNR.0000000000001341   
2019 Lundstrom BN, Gompel JV, Khadjevand F, Worrell G, Stead M. Chronic subthreshold cortical stimulation and stimulation-related EEG biomarkers for focal epilepsy. Brain Communications. 1: fcz010. PMID 31667473 DOI: 10.1093/braincomms/fcz010   
2019 Upadhya D, Kodali M, Gitai D, Castro OW, Zanirati G, Upadhya R, Attaluri S, Mitra E, Shuai B, Hattiangady B, Shetty AK. A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology. Aging and Disease. 10: 915-936. PMID 31595192 DOI: 10.14336/AD.2019.0720   
2019 Alzahrani H, Almalag HM, AlRuthia Y, Al-Hussain F, Balkhi B, Almutairi L, Algasem R, De Vol EB, Almarzouqi MR, Alsemari A. The Risk Of Seizure-Related Hospitalization Among Older Adults On Levetiracetam Monotherapy: A Retrospective Comparative Cohort Study. Neuropsychiatric Disease and Treatment. 15: 2781-2788. PMID 31576133 DOI: 10.2147/NDT.S221403   
2019 Ricobaraza A, Mora-Jimenez L, Puerta E, Sanchez-Carpintero R, Mingorance A, Artieda J, Nicolas MJ, Besne G, Bunuales M, Gonzalez-Aparicio M, Sola-Sevilla N, Valencia M, Hernandez-Alcoceba R. Epilepsy and neuropsychiatric comorbidities in mice carrying a recurrent Dravet syndrome SCN1A missense mutation. Scientific Reports. 9: 14172. PMID 31578435 DOI: 10.1038/s41598-019-50627-w   
2019 Sharma R, Leung WL, Zamani A, O'Brien TJ, Casillas Espinosa PM, Semple BD. Neuroinflammation in Post-Traumatic Epilepsy: Pathophysiology and Tractable Therapeutic Targets. Brain Sciences. 9. PMID 31717556 DOI: 10.3390/brainsci9110318   
2019 Dell KL, Cook MJ, Maturana MI. Deep Brain Stimulation for Epilepsy: Biomarkers for Optimization. Current Treatment Options in Neurology. 21: 47. PMID 31559493 DOI: 10.1007/s11940-019-0590-1   
2019 Garcia-Curran MM, Hall AM, Patterson KP, Shao M, Eltom N, Chen K, Dubé CM, Baram TZ. Dexamethasone attenuates hyperexcitability provoked by experimental febrile status epilepticus. Eneuro. PMID 31685676 DOI: 10.1523/ENEURO.0430-19.2019   
2019 Kim SH, Shim HS, Kang SM, Park H, Jin MH, Lee JH. Are there effects of lunar cycle on pediatric febrile seizure?: A single-center retrospective study (2005-2018). The Science of the Total Environment. 692: 589-594. PMID 31539966 DOI: 10.1016/j.scitotenv.2019.07.077   
2019 Mazumder AG, Kumari S, Singh D. Anticonvulsant action of a selective phosphatidylinositol-3-kinase inhibitor LY294002 in pentylenetetrazole-mediated convulsions in zebrafish. Epilepsy Research. 157: 106207. PMID 31563029 DOI: 10.1016/j.eplepsyres.2019.106207   
2019 Schidlitzki A, Bascuñana P, Srivastava PK, Welzel L, Twele F, Töllner K, Käufer C, Gericke B, Feleke R, Meier M, Polyak A, Ross TL, Gerhauser I, Bankstahl JP, Johnson MR, et al. Proof-of-concept that network pharmacology is effective to modify development of acquired temporal lobe epilepsy. Neurobiology of Disease. 104664. PMID 31678583 DOI: 10.1016/j.nbd.2019.104664   
2019 Wang A, Si Z, Li X, Lu L, Pan Y, Liu J. FK506 Attenuated Pilocarpine-Induced Epilepsy by Reducing Inflammation in Rats. Frontiers in Neurology. 10: 971. PMID 31572289 DOI: 10.3389/fneur.2019.00971   
2019 Corgie L, Huiban N, Quesnel L, Brocq FX, Boulard JF, Monteil M. Generalized Epileptic Seizure Induced by the Stroboscopic Effect of Helicopter Blades. Aerospace Medicine and Human Performance. 90: 891-895. PMID 31558198 DOI: 10.3357/AMHP.5367.2019   
2019 Tran DK, Paff M, Mnatsakanyan L, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. A Novel Robotic-Assisted Technique to Implant the Responsive Neurostimulation System. Operative Neurosurgery (Hagerstown, Md.). PMID 31538187 DOI: 10.1093/ons/opz226   
2019 Moustaki K, Buhler E, Martinez R, Watrin F, Represa A, Manent JB. Size of Subcortical Band Heterotopia Influences the Susceptibility to Hyperthermia-Induced Seizures in a Rat Model. Frontiers in Cellular Neuroscience. 13: 473. PMID 31680876 DOI: 10.3389/fncel.2019.00473   
2019 Tabrizi N, Zarvani A, Rezaei P, Cheraghmakani H, Alizadeh-Navaei R. Levetiracetam in genetic generalized epilepsy: A prospective unblinded active-controlled trial. Epilepsy Research. 157: 106214. PMID 31627041 DOI: 10.1016/j.eplepsyres.2019.106214   
2019 Witkin JM, Li G, Golani LK, Xiong W, Smith JL, Ping X, Rashid F, Jahan R, Cerne R, Cook JM, Jin X. The positive allosteric modulator of α2/3-containing GABAA receptors, KRM-II-81, is active in pharmaco-resistant models of epilepsy and reduces hyperexcitability after traumatic brain injury. The Journal of Pharmacology and Experimental Therapeutics. PMID 31694876 DOI: 10.1124/jpet.119.260968   
2019 Zub E, Canet G, Garbelli R, Blaquiere M, Rossini L, Pastori C, Sheikh M, Reutelingsperger C, Klement W, de Bock F, Audinat E, Givalois L, Solito E, Marchi N. The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901596R. PMID 31618599 DOI: 10.1096/fj.201901596R   
2019 Moura DMS, de Sales IRP, Brandão JA, Costa MR, Queiroz CM. Disentangling chemical and electrical effects of status epilepticus-induced dentate gyrus abnormalities. Epilepsy & Behavior : E&B. 106575. PMID 31704249 DOI: 10.1016/j.yebeh.2019.106575   
2019 Hartz AMS, Rempe RG, Soldner ELB, Pekcec A, Schlichtiger J, Kryscio R, Bauer B. Cytosolic phospholipase A2 is a key regulator of blood-brain barrier function in epilepsy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901369RR. PMID 31661303 DOI: 10.1096/fj.201901369RR