| Year |
Citation |
Score |
| 2020 |
Gatta E, Guidotti A, Saudagar V, Grayson DR, Aspesi D, Pandey SC, Pinna G. Epigenetic regulation of GABAergic neurotransmission and neurosteroid biosynthesis in alcohol use disorder. The International Journal of Neuropsychopharmacology. PMID 32968808 DOI: 10.1093/ijnp/pyaa073 |
1 |
|
| 2020 |
Paul SM, Pinna G, Guidotti A. Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective. Neurobiology of Stress. 12: 100215. PMID 32435665 DOI: 10.1016/j.ynstr.2020.100215 |
0.88 |
|
| 2020 |
Auta J, Gatta E, Davis JM, Zhang H, Pandey SC, Guidotti A. Essential role for neuronal nitric oxide synthase in acute ethanol-induced motor impairment. Nitric Oxide : Biology and Chemistry. PMID 32278831 DOI: 10.1016/j.niox.2020.04.003 |
0.92 |
|
| 2019 |
Gatta E, Grayson DR, Auta J, Saudagar V, Dong E, Chen Y, Krishnan HR, Drnevich J, Pandey SC, Guidotti A. Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1). Molecular Psychiatry. PMID 31239533 DOI: 10.1038/s41380-019-0449-6 |
1 |
|
| 2018 |
Matrisciano F, Dong E, Nicoletti F, Guidotti A. Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors. Frontiers in Molecular Neuroscience. 11: 423. PMID 30564095 DOI: 10.3389/fnmol.2018.00423 |
0.84 |
|
| 2018 |
Dong E, Locci V, Gatta E, Grayson DR, Guidotti A. N-Phthalyl-L-tryptophan (RG108), like clozapine (CLO), induces chromatin remodeling in brains of prenatally stressed mice. Molecular Pharmacology. PMID 30397000 DOI: 10.1124/mol.118.113415 |
1 |
|
| 2018 |
Dong E, Guidotti A, Zhang H, Pandey SC. Prenatal stress leads to synaptic remodeling and excessive alcohol intake comorbid with anxiety-like behaviors in adult offspring. Neuropharmacology. PMID 30016666 DOI: 10.1016/j.neuropharm.2018.07.010 |
0.84 |
|
| 2018 |
Auta J, Gatta E, Davis JM, Pandey SC, Guidotti A. Potential role for histone deacetylation in chronic diazepam-induced downregulation of α1-GABA receptor subunit expression. Pharmacology Research & Perspectives. 6: e00416. PMID 29951207 DOI: 10.1002/prp2.416 |
0.92 |
|
| 2018 |
Grayson DR, Guidotti A. DNA Methylation in Animal Models of Psychosis. Progress in Molecular Biology and Translational Science. 157: 105-132. PMID 29933947 DOI: 10.1016/bs.pmbts.2017.12.012 |
1 |
|
| 2017 |
Gatta E, Auta J, Gavin DP, Bhaumik DK, Grayson DR, Pandey SC, Guidotti A. Emerging role of one-carbon metabolism and DNA methylation enrichment on δ-containing GABAA receptor expression in the cerebellum of subjects with alcohol use disorders (AUD). The International Journal of Neuropsychopharmacology. PMID 29020412 DOI: 10.1093/ijnp/pyx075 |
1 |
|
| 2017 |
Auta J, Zhang H, Pandey SC, Guidotti A. Chronic Alcohol Exposure Differentially Alters One-Carbon Metabolism in Rat Liver and Brain. Alcoholism, Clinical and Experimental Research. PMID 28369960 DOI: 10.1111/acer.13382 |
0.92 |
|
| 2017 |
Zhubi A, Chen Y, Guidotti A, Grayson DR. Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 28229923 DOI: 10.1016/j.ijdevneu.2017.02.003 |
1 |
|
| 2016 |
Guidotti A, Grayson DR, Caruncho HJ. Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders. Frontiers in Cellular Neuroscience. 10: 89. PMID 27092053 DOI: 10.3389/fncel.2016.00089 |
1 |
|
| 2016 |
Gavin DP, Kusumo H, Zhang H, Guidotti A, Pandey SC. Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors. Alcoholism, Clinical and Experimental Research. 40: 263-72. PMID 26842245 DOI: 10.1111/acer.12965 |
0.96 |
|
| 2016 |
Matrisciano F, Panaccione I, Grayson DR, Nicoletti F, Guidotti A. Metabotropic Glutamate 2/3 Receptors and Epigenetic Modifications in Psychotic Disorders: A Review. Current Neuropharmacology. 14: 41-7. PMID 26813121 |
1 |
|
| 2016 |
Smith RC, Amiaz R, Si TM, Maayan L, Jin H, Boules S, Sershen H, Li C, Ren J, Liu Y, Youseff M, Lajtha A, Guidotti A, Weiser M, Davis JM. Varenicline Effects on Smoking, Cognition, and Psychiatric Symptoms in Schizophrenia: A Double-Blind Randomized Trial. Plos One. 11: e0143490. PMID 26730716 DOI: 10.1371/journal.pone.0143490 |
0.96 |
|
| 2016 |
Matrisciano F, Panaccione I, Dong E, Grayson DR, Guidotti A. Epigenetics: From basic biology to chromatin-modifying drugs and new potential clinical applications Neuromethods. 105: 3-18. DOI: 10.1007/978-1-4939-2754-8_1 |
0.96 |
|
| 2015 |
Labouesse MA, Dong E, Grayson D, Guidotti A, Meyer U. Maternal immune activation induces GAD1 and GAD2 promoter remodeling in the offspring prefrontal cortex. Epigenetics. 0. PMID 26575259 DOI: 10.1080/15592294.2015.1114202 |
1 |
|
| 2015 |
Grayson DR, Guidotti A. Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder. Epigenomics. PMID 26551091 DOI: 10.2217/epi.15.92 |
0.96 |
|
| 2015 |
Gavin DP, Kusumo H, Sharma RP, Guizzetti M, Guidotti A, Pandey SC. Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postmitotic neurons. Epigenomics. 7: 567-79. PMID 26111030 DOI: 10.2217/epi.15.12 |
1 |
|
| 2015 |
Dong E, Dzitoyeva SG, Matrisciano F, Tueting P, Grayson DR, Guidotti A. Brain-derived neurotrophic factor epigenetic modifications associated with schizophrenia-like phenotype induced by prenatal stress in mice. Biological Psychiatry. 77: 589-96. PMID 25444166 DOI: 10.1016/j.biopsych.2014.08.012 |
1 |
|
| 2015 |
Gavin DP, Kusumo H, Sharma RP, Guizzetti M, Guidotti A, Pandey SC. Gadd45b and N-methyl-d-aspartate induced DNA demethylation in postmitotic neurons Epigenomics. 7: 567-579. DOI: 10.2217/epi.15.12 |
1 |
|
| 2014 |
Dong E, Ruzicka WB, Grayson DR, Guidotti A. DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients. Schizophrenia Research. PMID 25476119 DOI: 10.1016/j.schres.2014.10.030 |
1 |
|
| 2014 |
Guidotti A, Dong E, Tueting P, Grayson DR. Modeling the molecular epigenetic profile of psychosis in prenatally stressed mice. Progress in Molecular Biology and Translational Science. 128: 89-101. PMID 25410542 DOI: 10.1016/B978-0-12-800977-2.00004-8 |
1 |
|
| 2014 |
Guidotti A, Grayson DR. DNA methylation and demethylation as targets for antipsychotic therapy. Dialogues in Clinical Neuroscience. 16: 419-29. PMID 25364290 |
1 |
|
| 2014 |
Zhubi A, Cook EH, Guidotti A, Grayson DR. Epigenetic mechanisms in autism spectrum disorder. International Review of Neurobiology. 115: 203-44. PMID 25131546 DOI: 10.1016/B978-0-12-801311-3.00006-8 |
1 |
|
| 2014 |
Agis-Balboa RC, Guidotti A, Pinna G. 5α-reductase type I expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients. Psychopharmacology. 231: 3569-80. PMID 24781515 DOI: 10.1007/s00213-014-3567-5 |
1 |
|
| 2014 |
Guidotti A, Auta J, Davis JM, Dong E, Gavin DP, Grayson DR, Sharma RP, Smith RC, Tueting P, Zhubi A. Toward the identification of peripheral epigenetic biomarkers of schizophrenia. Journal of Neurogenetics. 28: 41-52. PMID 24702539 DOI: 10.3109/01677063.2014.892485 |
1 |
|
| 2014 |
Zhubi A, Chen Y, Dong E, Cook EH, Guidotti A, Grayson DR. Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum. Translational Psychiatry. 4: e349. PMID 24448211 DOI: 10.1038/tp.2013.123 |
1 |
|
| 2014 |
Grayson DR, Guidotti A. 5-Methycytosine and 5-Hydroxymethylcytosine in Psychiatric Epigenetics Epigenetics in Psychiatry. 209-240. DOI: 10.1016/B978-0-12-417114-5.00010-3 |
1 |
|
| 2013 |
Auta J, Smith RC, Dong E, Tueting P, Sershen H, Boules S, Lajtha A, Davis J, Guidotti A. DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients. Schizophrenia Research. 150: 312-8. PMID 23938174 DOI: 10.1016/j.schres.2013.07.030 |
1 |
|
| 2013 |
Chase KA, Gavin DP, Guidotti A, Sharma RP. Histone methylation at H3K9: evidence for a restrictive epigenome in schizophrenia. Schizophrenia Research. 149: 15-20. PMID 23815974 DOI: 10.1016/j.schres.2013.06.021 |
1 |
|
| 2013 |
Guidotti A, Dong E, Gavin DP, Veldic M, Zhao W, Bhaumik DK, Pandey SC, Grayson DR. DNA methylation/demethylation network expression in psychotic patients with a history of alcohol abuse. Alcoholism, Clinical and Experimental Research. 37: 417-24. PMID 22958170 DOI: 10.1111/j.1530-0277.2012.01947.x |
1 |
|
| 2013 |
Grayson DR, Guidotti A. The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 138-66. PMID 22948975 DOI: 10.1038/npp.2012.125 |
1 |
|
| 2013 |
Matrisciano F, Tueting P, Dalal I, Kadriu B, Grayson DR, Davis JM, Nicoletti F, Guidotti A. Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice. Neuropharmacology. 68: 184-94. PMID 22564440 DOI: 10.1016/j.neuropharm.2012.04.013 |
1 |
|
| 2012 |
Sanna PP, Repunte-Canonigo V, Guidotti A. Gene profiling of laser-microdissected brain regions and individual cells in drug abuse and schizophrenia research. Methods in Molecular Biology (Clifton, N.J.). 829: 541-50. PMID 22231837 DOI: 10.1007/978-1-61779-458-2_34 |
1 |
|
| 2012 |
Kadriu B, Guidotti A, Chen Y, Grayson DR. DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain. The Journal of Comparative Neurology. 520: 1951-64. PMID 22134929 DOI: 10.1002/cne.23020 |
1 |
|
| 2012 |
Matrisciano F, Tueting P, Maccari S, Nicoletti F, Guidotti A. Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 929-38. PMID 22089319 DOI: 10.1038/npp.2011.274 |
1 |
|
| 2012 |
Gavin DP, Sharma RP, Chase KA, Matrisciano F, Dong E, Guidotti A. Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 531-42. PMID 22048458 DOI: 10.1038/npp.2011.221 |
1 |
|
| 2011 |
Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/j.1749-6632.2011.06216.x |
1 |
|
| 2011 |
Kadriu B, Gocel J, Larson J, Guidotti A, Davis JM, Nambiar MP, Auta J. Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage. Neuropharmacology. 61: 1463-9. PMID 21903116 DOI: 10.1016/j.neuropharm.2011.08.043 |
1 |
|
| 2011 |
Neff N, Mocchetti I, Guidotti A. Preface. Fifty years of Neuropharmacology a tribute to Ermino Costa. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 309. PMID 21722731 DOI: 10.1016/j.phrs.2011.05.012 |
1 |
|
| 2011 |
Guidotti A, Grayson DR. A neurochemical basis for an epigenetic vision of psychiatric disorders (1994-2009). Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 344-9. PMID 21699980 DOI: 10.1016/j.phrs.2011.05.026 |
1 |
|
| 2011 |
Mocchetti I, Guidotti A. The Fidia-Georgetown Institute for the Neurosciences (FGIN) 1985-1994. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 314-5. PMID 21683792 DOI: 10.1016/j.phrs.2011.05.015 |
1 |
|
| 2011 |
Matrisciano F, Dong E, Gavin DP, Nicoletti F, Guidotti A. Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain. Molecular Pharmacology. 80: 174-82. PMID 21505039 DOI: 10.1124/mol.110.070896 |
1 |
|
| 2011 |
Maloku E, Kadriu B, Zhubi A, Dong E, Pibiri F, Satta R, Guidotti A. Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1366-74. PMID 21368748 DOI: 10.1038/npp.2011.21 |
1 |
|
| 2011 |
Kadriu B, Guidotti A, Costa E, Davis JM, Auta J. Acute imidazenil treatment after the onset of DFP-induced seizure is more effective and longer lasting than midazolam at preventing seizure activity and brain neuropathology. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 136-45. PMID 21097996 DOI: 10.1093/toxsci/kfq356 |
1 |
|
| 2011 |
Guidotti A, Auta J, Chen Y, Davis JM, Dong E, Gavin DP, Grayson DR, Matrisciano F, Pinna G, Satta R, Sharma RP, Tremolizzo L, Tueting P. Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology. 60: 1007-16. PMID 21074545 DOI: 10.1016/j.neuropharm.2010.10.021 |
1 |
|
| 2011 |
Grayson DR, Kundakovic M, Chen Y, Dong E, Guidotti A. Epigenetic regulation of GABAergic targets in psychiatry Epigenetics and Human Health. 23-40. DOI: 10.1007/978-3-642-17426-1_2 |
1 |
|
| 2011 |
Tueting P, Costa E, Guidotti A. Epigenetic animal models of GABAergic deficit in mental disorders Neuromethods. 59: 243-260. DOI: 10.1007/978-1-61779-157-4_11 |
1 |
|
| 2010 |
Dong E, Chen Y, Gavin DP, Grayson DR, Guidotti A. Valproate induces DNA demethylation in nuclear extracts from adult mouse brain. Epigenetics : Official Journal of the Dna Methylation Society. 5: 730-5. PMID 20716949 DOI: 10.4161/epi.5.8.13053 |
1 |
|
| 2010 |
Tueting P, Davis JM, Veldic M, Pibiri F, Kadriu B, Guidotti A, Costa E. L-methionine decreases dendritic spine density in mouse frontal cortex. Neuroreport. 21: 543-8. PMID 20442623 DOI: 10.1097/WNR.0b013e3283373126 |
1 |
|
| 2010 |
Smith RC, Zhubi A, Maloku E, Sershen H, Lajtha A, Davis JM, Costa E, Guidotti A. Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers. Schizophrenia Research. 119: 269-70. PMID 20335008 DOI: 10.1016/j.schres.2010.02.1064 |
1 |
|
| 2010 |
Auta J, Kadriu B, Giusti P, Costa E, Guidotti A. Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives. Pharmacology, Biochemistry, and Behavior. 95: 383-9. PMID 20227434 DOI: 10.1016/j.pbb.2010.02.016 |
1 |
|
| 2010 |
Maloku E, Covelo IR, Hanbauer I, Guidotti A, Kadriu B, Hu Q, Davis JM, Costa E. Lower number of cerebellar Purkinje neurons in psychosis is associated with reduced reelin expression. Proceedings of the National Academy of Sciences of the United States of America. 107: 4407-11. PMID 20150511 DOI: 10.1073/pnas.0914483107 |
1 |
|
| 2009 |
Dong E, Grayson DR, Guidotti A, Costa E. Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation. Epigenomics. 1: 201-11. PMID 22122643 DOI: 10.2217/epi.09.2 |
1 |
|
| 2009 |
Grayson DR, Chen Y, Dong E, Kundakovic M, Guidotti A. From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia. Epigenetics : Official Journal of the Dna Methylation Society. 4: 144-9. PMID 19395859 DOI: 10.4161/epi.4.3.8534 |
1 |
|
| 2009 |
Zhubi A, Veldic M, Puri NV, Kadriu B, Caruncho H, Loza I, Sershen H, Lajtha A, Smith RC, Guidotti A, Davis JM, Costa E. An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes. Schizophrenia Research. 111: 115-22. PMID 19386473 DOI: 10.1016/j.schres.2009.03.020 |
1 |
|
| 2009 |
Pinna G, Costa E, Guidotti A. SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake. Current Opinion in Pharmacology. 9: 24-30. PMID 19157982 DOI: 10.1016/j.coph.2008.12.006 |
1 |
|
| 2009 |
Kadriu B, Guidotti A, Costa E, Auta J. Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage. Toxicology. 256: 164-74. PMID 19111886 DOI: 10.1016/j.tox.2008.11.021 |
1 |
|
| 2009 |
Guidotti A, Dong E, Kundakovic M, Satta R, Grayson DR, Costa E. Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends in Pharmacological Sciences. 30: 55-60. PMID 19110320 DOI: 10.1016/j.tips.2008.10.010 |
1 |
|
| 2009 |
Costa E, Chen Y, Dong E, Grayson DR, Kundakovic M, Maloku E, Ruzicka W, Satta R, Veldic M, Zhubi A, Guidotti A. GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability. Expert Review of Neurotherapeutics. 9: 87-98. PMID 19102671 DOI: 10.1586/14737175.9.1.87 |
1 |
|
| 2009 |
Kundakovic M, Chen Y, Guidotti A, Grayson DR. The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Molecular Pharmacology. 75: 342-54. PMID 19029285 DOI: 10.1124/mol.108.051763 |
1 |
|
| 2008 |
Satta R, Maloku E, Zhubi A, Pibiri F, Hajos M, Costa E, Guidotti A. Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 16356-61. PMID 18852456 DOI: 10.1073/pnas.0808699105 |
1 |
|
| 2008 |
Pibiri F, Kozikowski AP, Pinna G, Auta J, Kadriu B, Costa E, Guidotti A. The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 14169-74. PMID 18784370 DOI: 10.1073/pnas.0807172105 |
1 |
|
| 2008 |
Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proceedings of the National Academy of Sciences of the United States of America. 105: 13614-9. PMID 18757738 DOI: 10.1073/pnas.0805493105 |
1 |
|
| 2008 |
Auta J, Impagnatiello F, Kadriu B, Guidotti A, Costa E. Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem. Neuropharmacology. 55: 148-53. PMID 18555494 DOI: 10.1016/j.neuropharm.2008.05.002 |
1 |
|
| 2008 |
Pinna G, Agis-Balboa RC, Pibiri F, Nelson M, Guidotti A, Costa E. Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice. Neurochemical Research. 33: 1990-2007. PMID 18473173 DOI: 10.1007/s11064-008-9718-5 |
1 |
|
| 2008 |
Pibiri F, Nelson M, Guidotti A, Costa E, Pinna G. Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder. Proceedings of the National Academy of Sciences of the United States of America. 105: 5567-72. PMID 18391192 DOI: 10.1073/pnas.0801853105 |
1 |
|
| 2008 |
Costa E, Chen Y, Dong E, Grayson DR, Guidotti A, Veldic M. Reelin downregulation as a prospective treatment target for GABAergic dysfunction in schizophrenia Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. 341-363. DOI: 10.1007/978-0-387-76761-1_23 |
1 |
|
| 2007 |
AgÃs-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A. Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 18736-41. PMID 18003893 DOI: 10.1073/pnas.0709419104 |
1 |
|
| 2007 |
Costa E, Dong E, Grayson DR, Guidotti A, Ruzicka W, Veldic M. Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability. Epigenetics : Official Journal of the Dna Methylation Society. 2: 29-36. PMID 17965595 |
1 |
|
| 2007 |
Dong E, Guidotti A, Grayson DR, Costa E. Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters. Proceedings of the National Academy of Sciences of the United States of America. 104: 4676-81. PMID 17360583 DOI: 10.1073/pnas.0700529104 |
1 |
|
| 2007 |
Veldic M, Kadriu B, Maloku E, Agis-Balboa RC, Guidotti A, Davis JM, Costa E. Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophrenia Research. 91: 51-61. PMID 17270400 DOI: 10.1016/j.schres.2006.11.029 |
1 |
|
| 2007 |
Ruzicka WB, Zhubi A, Veldic M, Grayson DR, Costa E, Guidotti A. Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection. Molecular Psychiatry. 12: 385-97. PMID 17264840 DOI: 10.1038/sj.mp.4001954 |
1 |
|
| 2007 |
Guidotti A, Ruzicka W, Grayson DR, Veldic M, Pinna G, Davis JM, Costa E. S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. Neuroreport. 18: 57-60. PMID 17259861 DOI: 10.1097/WNR.0b013e32800fefd7 |
1 |
|
| 2006 |
Costa E, Dong E, Grayson DR, Ruzicka WB, Simonini MV, Veldic M, Guidotti A. Epigenetic targets in GABAergic neurons to treat schizophrenia. Advances in Pharmacology (San Diego, Calif.). 54: 95-117. PMID 17175812 DOI: 10.1016/S1054-3589(06)54005-0 |
1 |
|
| 2006 |
Sharma RP, Rosen C, Kartan S, Guidotti A, Costa E, Grayson DR, Chase K. Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophrenia Research. 88: 227-31. PMID 16996718 DOI: 10.1016/j.schres.2006.07.015 |
1 |
|
| 2006 |
AgÃs-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A. Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 14602-7. PMID 16984997 DOI: 10.1073/pnas.0606544103 |
1 |
|
| 2006 |
Rasmusson AM, Pinna G, Paliwal P, Weisman D, Gottschalk C, Charney D, Krystal J, Guidotti A. Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biological Psychiatry. 60: 704-13. PMID 16934764 DOI: 10.1016/j.biopsych.2006.03.026 |
1 |
|
| 2006 |
Tueting P, Doueiri MS, Guidotti A, Davis JM, Costa E. Reelin down-regulation in mice and psychosis endophenotypes. Neuroscience and Biobehavioral Reviews. 30: 1065-77. PMID 16769115 DOI: 10.1016/j.neubiorev.2006.04.001 |
1 |
|
| 2006 |
Grayson DR, Chen Y, Costa E, Dong E, Guidotti A, Kundakovic M, Sharma RP. The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacology & Therapeutics. 111: 272-86. PMID 16574235 DOI: 10.1016/j.pharmthera.2005.01.007 |
1 |
|
| 2006 |
Pinna G, Agis-Balboa RC, Zhubi A, Matsumoto K, Grayson DR, Costa E, Guidotti A. Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation. Proceedings of the National Academy of Sciences of the United States of America. 103: 4275-80. PMID 16537521 DOI: 10.1073/pnas.0600329103 |
1 |
|
| 2006 |
Pinna G, Costa E, Guidotti A. Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake. Psychopharmacology. 186: 362-72. PMID 16432684 DOI: 10.1007/s00213-005-0213-2 |
1 |
|
| 2006 |
Simonini MV, Camargo LM, Dong E, Maloku E, Veldic M, Costa E, Guidotti A. The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases. Proceedings of the National Academy of Sciences of the United States of America. 103: 1587-92. PMID 16432198 DOI: 10.1073/pnas.0510341103 |
1 |
|
| 2005 |
Ilijic E, Guidotti A, Mugnaini E. Moving up or moving down? Malpositioned cerebellar unipolar brush cells in reeler mouse. Neuroscience. 136: 633-47. PMID 16344141 DOI: 10.1016/j.neuroscience.2005.01.030 |
1 |
|
| 2005 |
Matsumoto K, Guidotti A, Costa E. [Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 126: 107-12. PMID 16205012 DOI: JST.JSTAGE/fpj/126.107 |
1 |
|
| 2005 |
Dong E, Agis-Balboa RC, Simonini MV, Grayson DR, Costa E, Guidotti A. Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 12578-83. PMID 16113080 DOI: 10.1073/pnas.0505394102 |
1 |
|
| 2005 |
Sharma RP, Grayson DR, Guidotti A, Costa E. Chromatin, DNA methylation and neuron gene regulation--the purpose of the package. Journal of Psychiatry & Neuroscience : Jpn. 30: 257-63. PMID 16049569 |
1 |
|
| 2005 |
Matsumoto K, Pinna G, Puia G, Guidotti A, Costa E. Social isolation stress-induced aggression in mice: a model to study the pharmacology of neurosteroidogenesis. Stress (Amsterdam, Netherlands). 8: 85-93. PMID 16019600 DOI: 10.1080/10253890500159022 |
1 |
|
| 2005 |
Auta J, Costa E, Davis JM, Guidotti A. Imidazenil: an antagonist of the sedative but not the anticonvulsant action of diazepam. Neuropharmacology. 49: 425-9. PMID 15964602 DOI: 10.1016/j.neuropharm.2005.04.005 |
1 |
|
| 2005 |
Grayson DR, Jia X, Chen Y, Sharma RP, Mitchell CP, Guidotti A, Costa E. Reelin promoter hypermethylation in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 9341-6. PMID 15961543 DOI: 10.1073/pnas.0503736102 |
1 |
|
| 2005 |
Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, Zhang X, Costa E. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology. 180: 191-205. PMID 15864560 DOI: 10.1007/s00213-005-2212-8 |
1 |
|
| 2005 |
Tremolizzo L, Doueiri MS, Dong E, Grayson DR, Davis J, Pinna G, Tueting P, Rodriguez-Menendez V, Costa E, Guidotti A. Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biological Psychiatry. 57: 500-9. PMID 15737665 DOI: 10.1016/j.biopsych.2004.11.046 |
1 |
|
| 2005 |
Veldic M, Guidotti A, Maloku E, Davis JM, Costa E. In psychosis, cortical interneurons overexpress DNA-methyltransferase 1. Proceedings of the National Academy of Sciences of the United States of America. 102: 2152-7. PMID 15684088 DOI: 10.1073/pnas.0409665102 |
1 |
|
| 2005 |
Pinna G, Costa E, Guidotti A. Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 2135-40. PMID 15677716 DOI: 10.1073/pnas.0409643102 |
1 |
|
| 2005 |
Noh JS, Sharma RP, Veldic M, Salvacion AA, Jia X, Chen Y, Costa E, Guidotti A, Grayson DR. DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proceedings of the National Academy of Sciences of the United States of America. 102: 1749-54. PMID 15671176 DOI: 10.1073/pnas.0409648102 |
1 |
|
| 2005 |
Costa E, Guidotti A, Veldić M. Should allosteric positive modulators of GABA(A) receptors be tested in the treatment of schizophrenia? Schizophrenia Research. 73: 367-8. PMID 15653283 DOI: 10.1016/j.schres.2004.08.005 |
1 |
|
| 2004 |
Pinna G, Agis-Balboa RC, Doueiri MS, Guidotti A, Costa E. Brain neurosteroids in gender-related aggression induced by social isolation. Critical Reviews in Neurobiology. 16: 75-82. PMID 15581402 DOI: 10.1615/CritRevNeurobiol.v16.i12.80 |
1 |
|
| 2004 |
Costa E, Davis JM, Dong E, Grayson DR, Guidotti A, Tremolizzo L, Veldic M. A GABAergic cortical deficit dominates schizophrenia pathophysiology. Critical Reviews in Neurobiology. 16: 1-23. PMID 15581395 |
1 |
|
| 2004 |
Carboni G, Tueting P, Tremolizzo L, Sugaya I, Davis J, Costa E, Guidotti A. Enhanced dizocilpine efficacy in heterozygous reeler mice relates to GABA turnover downregulation. Neuropharmacology. 46: 1070-81. PMID 15111013 DOI: 10.1016/j.neuropharm.2004.02.001 |
1 |
|
| 2004 |
Pinna G, Costa E, Guidotti A. Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids. Proceedings of the National Academy of Sciences of the United States of America. 101: 6222-5. PMID 15069199 DOI: 10.1073/pnas.0401479101 |
1 |
|
| 2004 |
Costa E, Grayson DR, Veldic M, Guidotti A. Neurochemical basis for an epigenetic vision of synaptic organization. International Review of Neurobiology. 59: 73-91. PMID 15006485 DOI: 10.1016/S0074-7742(04)59004-9 |
1 |
|
| 2004 |
Auta J, Costa E, Davis J, Guidotti A. Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity. Neuropharmacology. 46: 397-403. PMID 14975695 DOI: 10.1016/j.neuropharm.2003.09.010 |
1 |
|
| 2004 |
Cagetti E, Pinna G, Guidotti A, Baicy K, Olsen RW. Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function. Neuropharmacology. 46: 570-9. PMID 14975681 DOI: 10.1016/j.neuropharm.2003.10.001 |
1 |
|
| 2004 |
Veldic M, Caruncho HJ, Liu WS, Davis J, Satta R, Grayson DR, Guidotti A, Costa E. DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains. Proceedings of the National Academy of Sciences of the United States of America. 101: 348-53. PMID 14684836 DOI: 10.1073/pnas.2637013100 |
1 |
|
| 2003 |
Costa E, Grayson DR, Guidotti A. Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention? Molecular Interventions. 3: 220-9. PMID 14993449 DOI: 10.1124/mi.3.4.220 |
1 |
|
| 2003 |
Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A. GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability. Critical Reviews in Neurobiology. 15: 121-42. PMID 14977367 DOI: 10.1615/CritRevNeurobiol.v15.i2.20 |
1 |
|
| 2003 |
Dong E, Caruncho H, Liu WS, Smalheiser NR, Grayson DR, Costa E, Guidotti A. A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 5479-84. PMID 12707415 DOI: 10.1073/pnas.1031602100 |
1 |
|
| 2003 |
Larson J, Hoffman JS, Guidotti A, Costa E. Olfactory discrimination learning deficit in heterozygous reeler mice. Brain Research. 971: 40-6. PMID 12691835 DOI: 10.1016/S0006-8993(03)02353-9 |
1 |
|
| 2003 |
Pinna G, Dong E, Matsumoto K, Costa E, Guidotti A. In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine. Proceedings of the National Academy of Sciences of the United States of America. 100: 2035-40. PMID 12571361 DOI: 10.1073/pnas.0337642100 |
1 |
|
| 2003 |
Puia G, Mienville JM, Matsumoto K, Takahata H, Watanabe H, Costa E, Guidotti A. On the putative physiological role of allopregnanolone on GABA(A) receptor function. Neuropharmacology. 44: 49-55. PMID 12559121 DOI: 10.1016/S0028-3908(02)00341-6 |
1 |
|
| 2003 |
Hankiewicz J, Brint SU, Guidotti A, Costa E, Fiat D. In Vivo Natural-Abundance 17O/1H MRI of Rhesus Monkey Body in a Whole-Body Scanner Applied Magnetic Resonance. 24: 423-427. |
1 |
|
| 2002 |
Costa E, Chen Y, Davis J, Dong E, Noh JS, Tremolizzo L, Veldic M, Grayson DR, Guidotti A. REELIN and schizophrenia: a disease at the interface of the genome and the epigenome. Molecular Interventions. 2: 47-57. PMID 14993361 DOI: 10.1124/mi.2.1.47 |
1 |
|
| 2002 |
Tremolizzo L, Carboni G, Ruzicka WB, Mitchell CP, Sugaya I, Tueting P, Sharma R, Grayson DR, Costa E, Guidotti A. An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 99: 17095-100. PMID 12481028 DOI: 10.1073/pnas.262658999 |
1 |
|
| 2002 |
Costa E, Auta J, Grayson DR, Matsumoto K, Pappas GD, Zhang X, Guidotti A. GABAA receptors and benzodiazepines: a role for dendritic resident subunit mRNAs. Neuropharmacology. 43: 925-37. PMID 12423662 DOI: 10.1016/S0028-3908(02)00199-5 |
1 |
|
| 2002 |
Zhang H, Liu X, Zhang C, Mundo E, Macciardi F, Grayson DR, Guidotti AR, Holden JJ. Reelin gene alleles and susceptibility to autism spectrum disorders. Molecular Psychiatry. 7: 1012-7. PMID 12399956 DOI: 10.1038/sj.mp.4001124 |
1 |
|
| 2002 |
Rodriguez MA, Caruncho HJ, Costa E, Pesold C, Liu WS, Guidotti A. In Patas monkey, glutamic acid decarboxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas. The Journal of Comparative Neurology. 451: 279-88. PMID 12210139 DOI: 10.1002/cne.10341 |
1 |
|
| 2002 |
Kim HM, Qu T, Kriho V, Lacor P, Smalheiser N, Pappas GD, Guidotti A, Costa E, Sugaya K. Reelin function in neural stem cell biology. Proceedings of the National Academy of Sciences of the United States of America. 99: 4020-5. PMID 11891343 DOI: 10.1073/pnas.062698299 |
1 |
|
| 2002 |
Costa E, Davis J, Pesold C, Tueting P, Guidotti A. The heterozygote reeler mouse as a model for the development of a new generation of antipsychotics. Current Opinion in Pharmacology. 2: 56-62. PMID 11786309 DOI: 10.1016/S1471-4892(01)00121-7 |
1 |
|
| 2001 |
Guidotti A, Dong E, Matsumoto K, Pinna G, Rasmusson AM, Costa E. The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders. Brain Research. Brain Research Reviews. 37: 110-5. PMID 11744079 DOI: 10.1016/S0165-0173(01)00129-1 |
1 |
|
| 2001 |
Costa E, Davis J, Grayson DR, Guidotti A, Pappas GD, Pesold C. Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability. Neurobiology of Disease. 8: 723-42. PMID 11592844 DOI: 10.1006/nbdi.2001.0436 |
1 |
|
| 2001 |
Korpi ER, Mäkelä R, Romeo E, Guidotti A, Uusi-Oukari M, Furnari C, di Michele F, Sarviharju M, Xu M, Rosenberg PH. Increased behavioral neurosteroid sensitivity in a rat line selectively bred for high alcohol sensitivity. European Journal of Pharmacology. 421: 31-8. PMID 11408046 DOI: 10.1016/S0014-2999(01)01035-4 |
1 |
|
| 2001 |
Izzo E, Auta J, Impagnatiello F, Pesold C, Guidotti A, Costa E. Glutamic acid decarboxylase and glutamate receptor changes during tolerance and dependence to benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America. 98: 3483-8. PMID 11248104 DOI: 10.1073/pnas.051628698 |
1 |
|
| 2001 |
Liu WS, Pesold C, Rodriguez MA, Carboni G, Auta J, Lacor P, Larson J, Condie BG, Guidotti A, Costa E. Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse. Proceedings of the National Academy of Sciences of the United States of America. 98: 3477-82. PMID 11248103 DOI: 10.1073/pnas.051614698 |
1 |
|
| 2001 |
Dong E, Matsumoto K, Uzunova V, Sugaya I, Takahata H, Nomura H, Watanabe H, Costa E, Guidotti A. Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation. Proceedings of the National Academy of Sciences of the United States of America. 98: 2849-54. PMID 11226329 DOI: 10.1073/pnas.051628598 |
1 |
|
| 2000 |
Guidotti A, Auta J, Davis JM, Di-Giorgi-Gerevini V, Dwivedi Y, Grayson DR, Impagnatiello F, Pandey G, Pesold C, Sharma R, Uzunov D, Costa E, DiGiorgi Gerevini V. Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Archives of General Psychiatry. 57: 1061-9. PMID 11074872 |
1 |
|
| 2000 |
Guidotti A, Pesold C, Costa E. New neurochemical markers for psychosis: a working hypothesis of their operation. Neurochemical Research. 25: 1207-18. PMID 11059795 |
1 |
|
| 2000 |
Auta J, Lecca D, Nelson M, Guidotti A, Overstreet DH, Costa E, Javaid JI. Expression and function of striatal nAChRs differ in the flinders sensitive (FSL) and resistant (FRL) rat lines. Neuropharmacology. 39: 2624-31. PMID 11044732 DOI: 10.1016/S0028-3908(00)00082-4 |
1 |
|
| 2000 |
Rodriguez MA, Pesold C, Liu WS, Kriho V, Guidotti A, Pappas GD, Costa E. Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex. Proceedings of the National Academy of Sciences of the United States of America. 97: 3550-5. PMID 10725376 DOI: 10.1073/pnas.050589797 |
1 |
|
| 2000 |
Lacor PN, Grayson DR, Auta J, Sugaya I, Costa E, Guidotti A. Reelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulation. Proceedings of the National Academy of Sciences of the United States of America. 97: 3556-61. PMID 10725375 DOI: 10.1073/pnas.050589597 |
1 |
|
| 2000 |
Pinna G, Uzunova V, Matsumoto K, Puia G, Mienville JM, Costa E, Guidotti A. Brain allopregnanolone regulates the potency of the GABA(A) receptor agonist muscimol. Neuropharmacology. 39: 440-8. PMID 10698010 DOI: 10.1016/S0028-3908(99)00149-5 |
1 |
|
| 2000 |
Auta J, Guidotti A, Costa E. Imidazenil prevention of alprazolam-induced acquisition deficit in patas monkeys is devoid of tolerance. Proceedings of the National Academy of Sciences of the United States of America. 97: 2314-9. PMID 10696114 DOI: 10.1073/pnas.97.5.2314 |
1 |
|
| 2000 |
Smalheiser NR, Costa E, Guidotti A, Impagnatiello F, Auta J, Lacor P, Kriho V, Pappas GD. Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 1281-6. PMID 10655522 DOI: 10.1073/pnas.97.3.1281 |
1 |
|
| 1999 |
Auta J, Longone P, Guidotti A, Costa E. The regulation of hippocampal nicotinic acetylcholine receptors (nAChRs) after a protracted treatment with selective or nonselective nAChR agonists. Journal of Molecular Neuroscience : Mn. 13: 31-45. PMID 10691290 DOI: 10.1385/JMN:13:1-2:31 |
1 |
|
| 1999 |
Mihalek RM, Banerjee PK, Korpi ER, Quinlan JJ, Firestone LL, Mi ZP, Lagenaur C, Tretter V, Sieghart W, Anagnostaras SG, Sage JR, Fanselow MS, Guidotti A, Spigelman I, Li Z, et al. Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 12905-10. PMID 10536021 DOI: 10.1073/pnas.96.22.12905 |
1 |
|
| 1999 |
Saito M, Saito M, Berg MJ, Guidotti A, Marks N. Gangliosides attenuate ethanol-induced apoptosis in rat cerebellar granule neurons. Neurochemical Research. 24: 1107-15. PMID 10485581 DOI: 10.1023/A:1020704218574 |
1 |
|
| 1999 |
Matsumoto K, Uzunova V, Pinna G, Taki K, Uzunov DP, Watanabe H, Mienville JM, Guidotti A, Costa E. Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss. Neuropharmacology. 38: 955-63. PMID 10428414 DOI: 10.1016/S0028-3908(99)00018-0 |
1 |
|
| 1999 |
Tueting P, Costa E, Dwivedi Y, Guidotti A, Impagnatiello F, Manev R, Pesold C. The phenotypic characteristics of heterozygous reeler mouse. Neuroreport. 10: 1329-34. PMID 10363948 |
1 |
|
| 1999 |
Pesold C, Liu WS, Guidotti A, Costa E, Caruncho HJ. Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression. Proceedings of the National Academy of Sciences of the United States of America. 96: 3217-22. PMID 10077664 DOI: 10.1073/pnas.96.6.3217 |
1 |
|
| 1998 |
Liao Y, Kozikowski AP, Guidotti A, Costa E. Synthesis and pharmacological evaluation of benzofuran-acetamides as "antineophobic" mitochondrial DBI receptor complex ligands. Bioorganic & Medicinal Chemistry Letters. 8: 2099-102. PMID 9873493 DOI: 10.1016/S0960-894X(98)00374-6 |
1 |
|
| 1998 |
Impagnatiello F, Guidotti AR, Pesold C, Dwivedi Y, Caruncho H, Pisu MG, Uzunov DP, Smalheiser NR, Davis JM, Pandey GN, Pappas GD, Tueting P, Sharma RP, Costa E. A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 95: 15718-23. PMID 9861036 DOI: 10.1073/pnas.95.26.15718 |
1 |
|
| 1998 |
Longone P, Impagnatiello F, Mienville JM, Costa E, Guidotti A. Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro. Journal of Molecular Neuroscience : Mn. 11: 23-41. PMID 9826784 DOI: 10.1385/JMN:11:1:23 |
1 |
|
| 1998 |
Guidotti A, Costa E. Can the antidysphoric and anxiolytic profiles of selective serotonin reuptake inhibitors be related to their ability to increase brain 3 alpha, 5 alpha-tetrahydroprogesterone (allopregnanolone) availability? Biological Psychiatry. 44: 865-73. PMID 9807641 DOI: 10.1016/S0006-3223(98)00070-5 |
1 |
|
| 1998 |
Giorgetti M, Javaid JI, Davis JM, Costa E, Guidotti A, Appel SB, Brodie MS. Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability. The Journal of Pharmacology and Experimental Therapeutics. 287: 58-66. PMID 9765322 |
1 |
|
| 1998 |
Saito M, Guidotti A, Berg MJ, Marks N. The semisynthetic glycosphingolipid LIGA20 potently protects neurons against apoptosis. Annals of the New York Academy of Sciences. 845: 253-62. PMID 9668359 DOI: 10.1111/j.1749-6632.1998.tb09678.x |
1 |
|
| 1998 |
Marks N, Berg MJ, Guidotti A, Saito M. Activation of caspase-3 and apoptosis in cerebellar granule cells. Journal of Neuroscience Research. 52: 334-41. PMID 9590441 DOI: 10.1002/(SICI)1097-4547(19980501)52:3<334::AID-JNR9>3.0.CO;2-E |
1 |
|
| 1998 |
Uzunova V, Sheline Y, Davis JM, Rasmusson A, Uzunov DP, Costa E, Guidotti A. Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proceedings of the National Academy of Sciences of the United States of America. 95: 3239-44. PMID 9501247 DOI: 10.1073/pnas.95.6.3239 |
1 |
|
| 1998 |
Pesold C, Impagnatiello F, Pisu MG, Uzunov DP, Costa E, Guidotti A, Caruncho HJ. Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats. Proceedings of the National Academy of Sciences of the United States of America. 95: 3221-6. PMID 9501244 DOI: 10.1073/pnas.95.6.3221 |
1 |
|
| 1997 |
Pesold C, Caruncho HJ, Impagnatiello F, Berg MJ, Fritschy JM, Guidotti A, Costa E. Tolerance to diazepam and changes in GABA(A) receptor subunit expression in rat neocortical areas. Neuroscience. 79: 477-87. PMID 9200730 DOI: 10.1016/S0306-4522(96)00609-4 |
1 |
|
| 1997 |
Impagnatiello F, Oberto A, Longone P, Costa E, Guidotti A. 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide: a partial modulator of AMPA receptor desensitization devoid of neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 94: 7053-8. PMID 9192690 DOI: 10.1073/pnas.94.13.7053 |
1 |
|
| 1997 |
Caruncho HJ, Guidotti A, Lindstrom J, Costa E, Pesold C. Subcellular localization of the alpha 7 nicotinic receptor in rat cerebellar granule cell layer. Neuroreport. 8: 1431-3. PMID 9172148 |
1 |
|
| 1996 |
Longone P, Impagnatiello F, Guidotti A, Costa E. Reversible modification of GABAA receptor subunit mRNA expression during tolerance to diazepam-induced cognition dysfunction. Neuropharmacology. 35: 1465-73. PMID 9014162 |
1 |
|
| 1996 |
Arai A, Guidotti A, Costa E, Lynch G. Effect of the AMPA receptor modulator IDRA 21 on LTP in hippocampal slices. Neuroreport. 7: 2211-5. PMID 8930991 |
1 |
|
| 1996 |
Uzunov DP, Cooper TB, Costa E, Guidotti A. Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography. Proceedings of the National Academy of Sciences of the United States of America. 93: 12599-604. PMID 8901628 |
1 |
|
| 1996 |
Adinoff B, Anton R, Linnoila M, Guidotti A, Nemeroff CB, Bissette G. Cerebrospinal fluid concentrations of corticotropin-releasing hormone (CRH) and diazepam-binding inhibitor (DBI) during alcohol withdrawal and abstinence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 288-95. PMID 8873112 DOI: 10.1016/0893-133X(95)00212-V |
1 |
|
| 1996 |
Caruncho HJ, Liste I, Pesold C, Impagnatiello F, Guidotti A, Labandeira-Garcia JL. Semiquantitative immunocytochemical analysis of GABAA receptor subunit expression in the rat neostriatum. Receptors & Channels. 4: 85-92. PMID 8865360 |
1 |
|
| 1996 |
Oberto A, Marks N, Evans HL, Guidotti A. Lead (Pb+2) promotes apoptosis in newborn rat cerebellar neurons: pathological implications. The Journal of Pharmacology and Experimental Therapeutics. 279: 435-42. PMID 8859023 |
1 |
|
| 1996 |
Costa E, Guidotti A. Benzodiazepines on trial: a research strategy for their rehabilitation. Trends in Pharmacological Sciences. 17: 192-200. PMID 8669126 |
1 |
|
| 1996 |
Impagnatiello F, Pesold C, Longone P, Caruncho H, Fritschy JM, Costa E, Guidotti A. Modifications of gamma-aminobutyric acidA receptor subunit expression in rat neocortex during tolerance to diazepam. Molecular Pharmacology. 49: 822-31. PMID 8622632 |
1 |
|
| 1995 |
Auta J, Faust WB, Lambert P, Guidotti A, Costa E, Moerschbaecher JM. Comparison of the effects of full and partial allosteric modulators of GABA(A) receptors on complex behavioral processes in monkeys. Behavioural Pharmacology. 6: 323-332. PMID 11224341 |
1 |
|
| 1995 |
Cheney DL, Uzunov D, Guidotti A. Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone. Neuroreport. 6: 1697-700. PMID 8527744 |
0.64 |
|
| 1995 |
Zivkovic I, Thompson DM, Bertolino M, Uzunov D, DiBella M, Costa E, Guidotti A. 7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization. The Journal of Pharmacology and Experimental Therapeutics. 272: 300-9. PMID 7815345 |
1 |
|
| 1995 |
Thompson DM, Auta J, Guidotti A, Costa E. Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys. The Journal of Pharmacology and Experimental Therapeutics. 273: 1307-12. PMID 7791102 |
1 |
|
| 1995 |
Cheney DL, Uzunov D, Costa E, Guidotti A. Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4641-50. PMID 7790929 |
1 |
|
| 1995 |
Costa E, Auta J, Caruncho H, Guidotti A, Impagnatiello F, Pesold C, Thompson DM. A search for a new anticonvulsant and anxiolytic benzodiazepine devoid of side effects and tolerance liability. Advances in Biochemical Psychopharmacology. 48: 75-92. PMID 7653327 |
1 |
|
| 1995 |
Thompson DM, Guidotti A, DiBella M, Costa E. 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide (IDRA 21), a congener of aniracetam, potently abates pharmacologically induced cognitive impairments in patas monkeys. Proceedings of the National Academy of Sciences of the United States of America. 92: 7667-71. PMID 7644474 DOI: 10.1073/pnas.92.17.7667 |
1 |
|
| 1995 |
De Stefanis P, Impagnatiello F, Berkovich A, Guidotti A. Inhibitory effect of ODN, a naturally occurring processing product of diazepam binding inhibitor, on secretagogues-induced insulin secretion. Regulatory Peptides. 56: 153-65. PMID 7544471 |
0.88 |
|
| 1995 |
Uzunov DP, Zivkovich I, Pirkle WH, Costa E, Guidotti A. Enantiomeric resolution with a new chiral stationary phase of 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide, a cognition-enhancing benzothiadiazine derivative. Journal of Pharmaceutical Sciences. 84: 937-42. PMID 7500277 DOI: 10.1002/jps.2600840807 |
1 |
|
| 1994 |
George MS, Guidotti A, Rubinow D, Pan B, Mikalauskas K, Post RM. CSF neuroactive steroids in affective disorders: pregnenolone, progesterone, and DBI. Biological Psychiatry. 35: 775-80. PMID 8043707 DOI: 10.1016/0006-3223(94)91139-8 |
1 |
|
| 1994 |
Costa E, Auta J, Guidotti A, Korneyev A, Romeo E. The pharmacology of neurosteroidogenesis. The Journal of Steroid Biochemistry and Molecular Biology. 49: 385-9. PMID 8043504 |
1 |
|
| 1994 |
Romeo E, Cheney DL, Zivkovic I, Costa E, Guidotti A. Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone. The Journal of Pharmacology and Experimental Therapeutics. 270: 89-96. PMID 8035347 |
1 |
|
| 1994 |
Costa E, Armstrong DM, Guidotti A, Kharlamov A, Kiedrowski L, Manev H, Polo A, Wroblewski JT. Gangliosides in the protection against glutamate excitotoxicity. Progress in Brain Research. 101: 357-73. PMID 8029464 |
1 |
|
| 1994 |
Kharlamov A, Zivkovic I, Polo A, Armstrong DM, Costa E, Guidotti A. LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit. Proceedings of the National Academy of Sciences of the United States of America. 91: 6303-7. PMID 8022776 DOI: 10.1073/pnas.91.14.6303 |
1 |
|
| 1994 |
Auta J, Giusti P, Guidotti A, Costa E. Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat. The Journal of Pharmacology and Experimental Therapeutics. 270: 1262-9. PMID 7932179 |
1 |
|
| 1994 |
Perillo MA, Guidotti A, Costa E, Yu RK, Maggio B. Modulation of phospholipases A2 and C activities against dilauroylphosphorylcholine in mixed monolayers with semisynthetic derivatives of ganglioside and sphingosine. Molecular Membrane Biology. 11: 119-26. PMID 7920864 DOI: 10.3109/09687689409162229 |
1 |
|
| 1994 |
Polo A, Kirschner G, Guidotti A, Costa E. Brain content of glycosphingolipids after oral administration of monosialogangliosides GM1 and LIGA20 to rats. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 21: 41-53. PMID 7910019 |
1 |
|
| 1994 |
Rius RA, Guidotti A, Costa E. Pituitary adenylate cyclase activating polypeptide (PACAP) potently enhances tyrosine hydroxylase (TH) expression in adrenal chromaffin cells. Life Sciences. 54: 1735-43. PMID 7909910 |
1 |
|
| 1994 |
van Kammen DP, Guidotti A, Neylan T, Guarneri P, Kelley ME, Gurklis J, Gilbertson MW, Peters JL, Costa E. CSF levels of diazepam-binding inhibitor correlate with REM latency in schizophrenia, a pilot study. European Archives of Psychiatry and Clinical Neuroscience. 244: 216-22. PMID 7888420 |
1 |
|
| 1994 |
Costa E, Cheney DL, Grayson DR, Korneyev A, Longone P, Pani L, Romeo E, Zivkovich E, Guidotti A. Pharmacology of neurosteroid biosynthesis. Role of the mitochondrial DBI receptor (MDR) complex. Annals of the New York Academy of Sciences. 746: 223-42. PMID 7825880 |
1 |
|
| 1994 |
Hawley RJ, Nemeroff CB, Bissette G, Guidotti A, Rawlings R, Linnoila M. Neurochemical correlates of sympathetic activation during severe alcohol withdrawal. Alcoholism, Clinical and Experimental Research. 18: 1312-6. PMID 7695023 DOI: 10.1111/j.1530-0277.1994.tb01429.x |
1 |
|
| 1994 |
Virkkunen M, Kallio E, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, Bissette G, Kalogeras K, Karonen SL. Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry. 51: 28-33. PMID 7506516 DOI: 10.1001/archpsyc.1994.03950010028004 |
1 |
|
| 1994 |
Virkkunen M, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, Bissette G, Kalogeras K, Karonen SL, Linnoila M. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry. 51: 20-7. PMID 7506515 DOI: 10.1001/archpsyc.1994.03950010020003 |
1 |
|
| 1993 |
Kharlamov A, Guidotti A, Costa E, Hayes R, Armstrong D. Semisynthetic sphingolipids prevent protein kinase C translocation and neuronal damage in the perifocal area following a photochemically induced thrombotic brain cortical lesion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2483-94. PMID 8501519 |
1 |
|
| 1993 |
Kozikowski AP, Ma D, Brewer J, Sun S, Costa E, Romeo E, Guidotti A. Chemistry, binding affinities, and behavioral properties of a new class of "antineophobic" mitochondrial DBI receptor complex (mDRC) ligands. Journal of Medicinal Chemistry. 36: 2908-20. PMID 8411007 |
1 |
|
| 1993 |
Korneyev A, Pan BS, Polo A, Romeo E, Guidotti A, Costa E. Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo. Journal of Neurochemistry. 61: 1515-24. PMID 8397297 |
1 |
|
| 1993 |
Cavallaro S, Pani L, Guidotti A, Costa E. ACTH-induced mitochondrial DBI receptor (MDR) and diazepam binding inhibitor (DBI) expression in adrenals of hypophysectomized rats is not cause-effect related to its immediate steroidogenic action. Life Sciences. 53: 1137-47. PMID 8396705 |
1 |
|
| 1993 |
Giusti P, Ducić I, Puia G, Arban R, Walser A, Guidotti A, Costa E. Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors. The Journal of Pharmacology and Experimental Therapeutics. 266: 1018-28. PMID 8394902 |
1 |
|
| 1993 |
Korneyev AY, Costa E, Guidotti A. During anesthetic-induced activation of hypothalamic pituitary adrenal axis, blood-borne steroids fail to contribute to the anesthetic effect. Neuroendocrinology. 57: 559-65. PMID 8391666 |
1 |
|
| 1993 |
Berkovich A, Ferrarese C, Cavaletti G, Alho H, Marzorati C, Bianchi G, Guidotti A, Costa E. Topology of two DBI receptors in human lymphocytes. Life Sciences. 52: 1265-77. PMID 8385252 |
1 |
|
| 1993 |
van Kammen DP, Guidotti A, Kelley ME, Gurklis J, Guarneri P, Gilbertson MW, Yao JK, Peters J, Costa E. CSF diazepam binding inhibitor and schizophrenia: clinical and biochemical relationships. Biological Psychiatry. 34: 515-22. PMID 8274578 |
1 |
|
| 1993 |
Perillo MA, Polo A, Guidotti A, Costa E, Maggio B. Molecular parameters of semisynthetic derivatives of gangliosides and sphingosine in monolayers at the air-water interface. Chemistry and Physics of Lipids. 65: 225-38. PMID 8269552 DOI: 10.1016/0009-3084(93)90020-4 |
1 |
|
| 1993 |
Korneyev A, Guidotti A, Costa E. Regional and interspecies differences in brain progesterone metabolism. Journal of Neurochemistry. 61: 2041-7. PMID 8245959 |
1 |
|
| 1993 |
Romeo E, Cavallaro S, Korneyev A, Kozikowski AP, Ma D, Polo A, Costa E, Guidotti A. Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex. The Journal of Pharmacology and Experimental Therapeutics. 267: 462-71. PMID 8229777 |
1 |
|
| 1993 |
Manev H, Guidotti A, Costa E. Protection by gangliosides against glutamate excitotoxicity. Advances in Lipid Research. 25: 269-88. PMID 8103620 |
1 |
|
| 1993 |
Auta J, Romeo E, Kozikowski A, Ma D, Costa E, Guidotti A. Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives. The Journal of Pharmacology and Experimental Therapeutics. 265: 649-56. PMID 8098760 |
1 |
|
| 1993 |
Lombardi G, Szekely AM, Bristol LA, Guidotti A, Manev H. Induction of ornithine decarboxylase by N-methyl-D-aspartate receptor activation is unrelated to potentiation of glutamate excitotoxicity by polyamines in cerebellar granule neurons. Journal of Neurochemistry. 60: 1317-24. PMID 8095973 |
1 |
|
| 1993 |
Costa E, Armstrong D, Guidotti A, Kharlamov A, Kiedrowski L, Wroblewski JT. Ganglioside GM1 and its semisynthetic lysogangliosides reduce glutamate neurotoxicity by a novel mechanism. Advances in Experimental Medicine and Biology. 341: 129-41. PMID 7906915 |
1 |
|
| 1992 |
Rothstein JD, Guidotti A, Tinuper P, Cortelli P, Avoni P, Plazzi G, Lugaresi E, Schoch P, Montagna P. Endogenous benzodiazepine receptor ligands in idiopathic recurring stupor. Lancet. 340: 1002-4. PMID 1357403 DOI: 10.1016/0140-6736(92)93011-B |
1 |
|
| 1992 |
Olasmaa M, Guidotti A, Costa E. Vasoactive intestinal polypeptide facilitates tyrosine hydroxylase induction by cholinergic agonists in bovine adrenal chromaffin cells. Molecular Pharmacology. 41: 456-64. PMID 1347640 |
1 |
|
| 1992 |
Rothstein JD, Guidotti A, Costa E. Release of endogenous benzodiazepine receptor ligands (endozepines) from cultured neurons. Neuroscience Letters. 143: 210-4. PMID 1331901 |
1 |
|
| 1992 |
Romeo E, Auta J, Kozikowski AP, Ma D, Papadopoulos V, Puia G, Costa E, Guidotti A. 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). The Journal of Pharmacology and Experimental Therapeutics. 262: 971-8. PMID 1326631 |
1 |
|
| 1992 |
Giusti P, Romeo E, Auta J, Guidotti A. Structural variety of GABAA receptors and specificity of benzodiazepines pharmacological profiles. Advances in Biochemical Psychopharmacology. 47: 163-77. PMID 1324570 |
0.92 |
|
| 1992 |
Papadopoulos V, Guarneri P, Kreuger KE, Guidotti A, Costa E. Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 5113-7. PMID 1317581 |
1 |
|
| 1992 |
Rothstein JD, Garland W, Puia G, Guidotti A, Weber RJ, Costa E. Purification and characterization of naturally occurring benzodiazepine receptor ligands in rat and human brain. Journal of Neurochemistry. 58: 2102-15. PMID 1315376 |
1 |
|
| 1992 |
Costa E, Kharlamov A, Guidotti A, Hayes R, Armstrong D. Sequelae of biochemical events following photochemical injury of rat sensory-motor cortex: mechanism of ganglioside protection. Patologicheskaia Fiziologiia I èKsperimental'Naia Terapiia. 17-23. PMID 1303498 |
1 |
|
| 1992 |
Cavallaro S, Korneyev A, Guidotti A, Costa E. Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland. Proceedings of the National Academy of Sciences of the United States of America. 89: 10598-602. PMID 1279686 |
1 |
|
| 1991 |
Massotti M, Schlichting JL, Antonacci MD, Giusti P, Memo M, Costa E, Guidotti A. gamma-Aminobutyric acidA receptor heterogeneity in rat central nervous system: studies with clonazepam and other benzodiazepine ligands. The Journal of Pharmacology and Experimental Therapeutics. 256: 1154-60. PMID 1848629 |
1 |
|
| 1991 |
Ferrarese C, Guidotti A, Costa E, Miletich RS, Rice KC, de Costa BR, Fulham MJ, Di Chiro G. In vivo study of NMDA-sensitive glutamate receptor by fluorothienylcyclohexylpiperidine [correction of fluorothienylcycloexylpiperidine], a possible ligand for positron emission tomography. Neuropharmacology. 30: 899-905. PMID 1685770 |
1 |
|
| 1991 |
Manev H, Favaron M, Siman R, Guidotti A, Costa E. Glutamate neurotoxicity is independent of calpain I inhibition in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 57: 1288-95. PMID 1680162 |
1 |
|
| 1991 |
Giusti P, Guidetti G, Costa E, Guidotti A. The preferential antagonism of pentylenetetrazole proconflict responses differentiates a class of anxiolytic benzodiazepines with potential antipanic action. The Journal of Pharmacology and Experimental Therapeutics. 257: 1062-8. PMID 1675286 |
1 |
|
| 1991 |
Papadopoulos V, Berkovich A, Krueger KE, Costa E, Guidotti A. Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors. Endocrinology. 129: 1481-8. PMID 1651852 DOI: 10.1210/endo-129-3-1481 |
1 |
|
| 1991 |
Costa E, Guidotti A. Diazepam binding inhibitor (DBI): a peptide with multiple biological actions. Life Sciences. 49: 325-44. PMID 1649940 DOI: 10.1016/0024-3205(91)90440-M |
1 |
|
| 1991 |
Massotti M, Slobodyansky E, Konkel D, Costa E, Guidotti A. Regulation of diazepam binding inhibitor in rat adrenal gland by adrenocorticotropin. Endocrinology. 129: 591-6. PMID 1649741 DOI: 10.1210/endo-129-2-591 |
1 |
|
| 1990 |
Guarneri P, Berkovich A, Guidotti A, Costa E. A study of diazepam binding inhibitor (DBI) processing products in human cerebrospinal fluid and in postmortem human brain. Neuropharmacology. 29: 419-28. PMID 2356001 |
1 |
|
| 1990 |
Roy A, DeJong J, Adinoff B, Barbaccia M, Costa E, Guidotti A, Linnoila M. CSF diazepam-binding inhibitor in alcoholics and normal controls. Psychiatry Research. 31: 261-6. PMID 2333358 |
1 |
|
| 1990 |
Guarneri P, Guidotti A, Costa E. On the processing of diazepam binding inhibitor (DBI) in human brain. Advances in Biochemical Psychopharmacology. 46: 201-11. PMID 2291443 |
1 |
|
| 1990 |
de Erausquin GA, Manev H, Guidotti A, Costa E, Brooker G. Gangliosides normalize distorted single-cell intracellular free Ca2+ dynamics after toxic doses of glutamate in cerebellar granule cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 8017-21. PMID 2236016 DOI: 10.1073/pnas.87.20.8017 |
1 |
|
| 1990 |
Manev H, Favaron M, De Erausquin G, Guidotti A, Brooker G, Costa E. Destabilization of ionized Ca2+ homeostasis in excitatory amino acid neurotoxicity: antagonism by glycosphingolipids. Cell Biology International Reports. 14: 3-14. PMID 2185894 DOI: 10.1016/0309-1651(90)90066-8 |
1 |
|
| 1990 |
Olasmaa M, Rothstein JD, Guidotti A, Weber RJ, Paul SM, Spector S, Zeneroli ML, Baraldi M, Costa E. Endogenous benzodiazepine receptor ligands in human and animal hepatic encephalopathy. Journal of Neurochemistry. 55: 2015-23. PMID 2172467 |
1 |
|
| 1990 |
Bovolin P, Schlichting J, Miyata M, Ferrarese C, Guidotti A, Alho H. Distribution and characterization of diazepam binding inhibitor (DBI) in peripheral tissues of rat. Regulatory Peptides. 29: 267-81. PMID 2171047 |
0.56 |
|
| 1990 |
Manev H, Costa E, Wroblewski JT, Guidotti A. Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2789-97. PMID 2165013 |
1 |
|
| 1990 |
Berkovich A, McPhie P, Campagnone M, Guidotti A, Hensley P. A natural processing product of rat diazepam binding inhibitor, triakontatetraneuropeptide (diazepam binding inhibitor 17-50) contains an alpha-helix, which allows discrimination between benzodiazepine binding site subtypes. Molecular Pharmacology. 37: 164-72. PMID 2154668 |
1 |
|
| 1990 |
Manev H, Favaron M, Vicini S, Guidotti A. Ganglioside-mediated protection from glutamate-induced neuronal death. Acta Neurobiologiae Experimentalis. 50: 475-88. PMID 1983378 |
1 |
|
| 1990 |
Guidotti A, Manev H, Favaron M, Brooker G, Costa E. Protection by natural and semisynthetic gangliosides from Ca2(+)-dependent neurotoxicity caused by excitatory amino acid (EAA) neurotransmitters. Advances in Experimental Medicine and Biology. 268: 135-44. PMID 1981639 |
1 |
|
| 1990 |
Guidotti A, Antonacci MD, Giusti P, Massotti M, Memo M, Schlichting JL. The differences in the pharmacological profiles of various benzodiazepine recognition site ligands may be associated with GABAA receptor structural diversity. Advances in Biochemical Psychopharmacology. 46: 73-87. PMID 1981305 |
0.76 |
|
| 1990 |
Krueger KE, Mukhin AG, Antkiewicz-Michaluk L, Santi MR, Grayson DR, Guidotti A, Sprengel R, Werner P, Seeburg PH. Purification, cloning, and expression of a peripheral-type benzodiazepine receptor. Advances in Biochemical Psychopharmacology. 46: 1-13. PMID 1963260 |
1 |
|
| 1990 |
Favaron M, Manev H, Siman R, Bertolino M, Szekely AM, DeErausquin G, Guidotti A, Costa E. Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death. Proceedings of the National Academy of Sciences of the United States of America. 87: 1983-7. PMID 1689850 |
1 |
|
| 1990 |
Manev H, Favaron M, Vicini S, Guidotti A, Costa E. Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids. The Journal of Pharmacology and Experimental Therapeutics. 252: 419-27. PMID 1688945 |
1 |
|
| 1989 |
Roy A, Pickar D, Gold P, Barbaccia M, Guidotti A, Costa E, Linnoila M. Diazepam-binding inhibitor and corticotropin-releasing hormone in cerebrospinal fluid. Acta Psychiatrica Scandinavica. 80: 287-91. PMID 2816471 DOI: 10.1111/j.1600-0447.1989.tb01339.x |
1 |
|
| 1989 |
Slobodyansky E, Guidotti A, Wambebe C, Berkovich A, Costa E. Isolation and characterization of a rat brain triakontatetraneuropeptide, a posttranslational product of diazepam binding inhibitor: specific action at the Ro 5-4864 recognition site. Journal of Neurochemistry. 53: 1276-84. PMID 2769267 |
1 |
|
| 1989 |
Manev H, Favaron M, Guidotti A, Costa E. Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death. Molecular Pharmacology. 36: 106-12. PMID 2568579 |
1 |
|
| 1989 |
Olasmaa M, Guidotti A, Costa E, Rothstein JD, Goldman ME, Weber RJ, Paul SM. Endogenous benzodiazepines in hepatic encephalopathy. Lancet. 1: 491-2. PMID 2563854 |
1 |
|
| 1989 |
Sprengel R, Werner P, Seeburg PH, Mukhin AG, Santi MR, Grayson DR, Guidotti A, Krueger KE. Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor. The Journal of Biological Chemistry. 264: 20415-21. PMID 2555358 |
1 |
|
| 1989 |
Rothstein JD, McKhann G, Guarneri P, Barbaccia ML, Guidotti A, Costa E. Cerebrospinal fluid content of diazepam binding inhibitor in chronic hepatic encephalopathy. Annals of Neurology. 26: 57-62. PMID 2549847 DOI: 10.1002/ana.410260109 |
1 |
|
| 1989 |
Gillis RA, Namath IJ, Easington C, Abrahams TP, Guidotti A, Quest JA, Hamosh P, Taveira da Silva AM. Drug interaction with gamma-aminobutyric acid/benzodiazepine receptors at the ventral surface of the medulla results in pronounced changes in cardiorespiratory activity. The Journal of Pharmacology and Experimental Therapeutics. 248: 863-70. PMID 2537419 |
1 |
|
| 1989 |
Alho H, Bovolin P, Jenkins D, Guidotti A, Costa E. Cellular and subcellular localization of an octadecaneuropeptide derived from diazepam binding inhibitor: immunohistochemical studies in the rat brain. Journal of Chemical Neuroanatomy. 2: 301-18. PMID 2482048 |
1 |
|
| 1988 |
Barbaccia ML, Costa E, Guidotti A. Endogenous ligands for high-affinity recognition sites of psychotropic drugs. Annual Review of Pharmacology and Toxicology. 28: 451-76. PMID 3289493 DOI: 10.1146/annurev.pa.28.040188.002315 |
1 |
|
| 1988 |
Favaron M, Manev H, Alho H, Bertolino M, Ferret B, Guidotti A, Costa E. Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proceedings of the National Academy of Sciences of the United States of America. 85: 7351-5. PMID 2902628 |
1 |
|
| 1988 |
Antkiewicz-Michaluk L, Mukhin AG, Guidotti A, Krueger KE. Purification and characterization of a protein associated with peripheral-type benzodiazepine binding sites. The Journal of Biological Chemistry. 263: 17317-21. PMID 2846560 |
0.36 |
|
| 1988 |
Guidotti A, Slobodyansky E, Berkovich A, Cox DH, Wambebe C. The heterogeneity of GABAA receptors and the multiplicity of endogenous ligands for their allosteric modulatory centers. Advances in Biochemical Psychopharmacology. 45: 219-26. PMID 2845737 |
1 |
|
| 1988 |
Antkiewicz-Michaluk L, Guidotti A, Krueger KE. Molecular characterization and mitochondrial density of a recognition site for peripheral-type benzodiazepine ligands. Molecular Pharmacology. 34: 272-8. PMID 2843747 |
0.36 |
|
| 1988 |
Santi MR, Cox DH, Guidotti A. Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord. Journal of Neurochemistry. 50: 1080-6. PMID 2831297 |
1 |
|
| 1988 |
Costa E, Berkovich A, Wambebe C, Guidotti A. Terminology for ligands of the allosteric modulatory center of GABA-operated Cl- channels. Advances in Biochemical Psychopharmacology. 45: 367-74. PMID 2459924 |
1 |
|
| 1988 |
Roy A, Adinoff B, Roehrich L, Lamparski D, Custer R, Lorenz V, Barbaccia M, Guidotti A, Costa E, Linnoila M. Pathological gambling. A psychobiological study. Archives of General Psychiatry. 45: 369-73. PMID 2451490 DOI: 10.1001/archpsyc.1988.01800280085011 |
1 |
|
| 1987 |
Ferrarese C, Vaccarino F, Alho H, Mellstrom B, Costa E, Guidotti A. Subcellular location and neuronal release of diazepam binding inhibitor. Journal of Neurochemistry. 48: 1093-102. PMID 3819722 |
1 |
|
| 1987 |
Alho H, Miyata M, Korpi E, Kiianmaa K, Guidotti A. Studies of a brain polypeptide functioning as a putative endogenous ligand to benzodiazepine recognition sites in rats selectively bred for alcohol related behavior. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 1: 637-41. PMID 3426746 |
0.56 |
|
| 1987 |
Costa E, Berkovich A, Guidotti A. The regulation of GABAergic receptors by a novel family of endogenous neuropeptides. Life Sciences. 41: 799-803. PMID 3039273 |
1 |
|
| 1987 |
Miyata M, Mocchetti I, Ferrarese C, Guidotti A, Costa E. Protracted treatment with diazepam increases the turnover of putative endogenous ligands for the benzodiazepine/beta-carboline recognition site. Proceedings of the National Academy of Sciences of the United States of America. 84: 1444-8. PMID 3029781 DOI: 10.1073/pnas.84.5.1444 |
1 |
|
| 1987 |
Vaccarino FM, Alho H, Santi MR, Guidotti A. Coexistence of GABA receptors and GABA-modulin in primary cultures of rat cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 65-76. PMID 3027277 |
1 |
|
| 1987 |
Novelli A, Nicoletti F, Wroblewski JT, Alho H, Costa E, Guidotti A. Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 40-7. PMID 2879898 |
1 |
|
| 1987 |
Vaccarino F, Guidotti A, Costa E. Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons. Proceedings of the National Academy of Sciences of the United States of America. 84: 8707-11. PMID 2825205 |
1 |
|
| 1987 |
Fujimoto M, Kataoka Y, Guidotti A, Hanbauer I. Effect of gamma-aminobutyric acidA receptor agonists and antagonists on the release of enkephalin-containing peptides from dog adrenal gland. The Journal of Pharmacology and Experimental Therapeutics. 243: 195-9. PMID 2822897 |
0.52 |
|
| 1987 |
Ferrarese C, Alho H, Guidotti A, Costa E. Co-localization and co-release of GABA and putative allosteric modulators of GABA receptor. Neuropharmacology. 26: 1011-8. PMID 2821427 |
1 |
|
| 1986 |
Ferrero P, Costa E, Conti-Tronconi B, Guidotti A. A diazepam binding inhibitor (DBI)-like neuropeptide is detected in human brain. Brain Research. 399: 136-42. PMID 3801915 |
1 |
|
| 1986 |
Ferrero P, Conti-Tronconi B, Guidotti A. DBI, an anxiogenic neuropeptide found in human brain. Advances in Biochemical Psychopharmacology. 41: 177-85. PMID 3739846 |
0.6 |
|
| 1986 |
Ferrero P, Santi MR, Conti-Tronconi B, Costa E, Guidotti A. Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 83: 827-31. PMID 3456171 |
1 |
|
| 1986 |
Guidotti A, Santi MR, Berkovich A, Ferrarese C, Costa E. Structure-activity relationship of peptide fragments derived from DBI (diazepam binding inhibitor), a putative endogenous ligand of benzodiazepine recognition sites. Clinical Neuropharmacology. 9: 217-9. PMID 3032426 |
1 |
|
| 1986 |
Costa E, Alho H, Santi MR, Ferrero P, Guidotti A. Cotransmission at GABAergic synapses. Progress in Brain Research. 68: 343-56. PMID 3031734 |
1 |
|
| 1986 |
Barbaccia ML, Costa E, Ferrero P, Guidotti A, Roy A, Sunderland T, Pickar D, Paul SM, Goodwin FK. Diazepam-binding inhibitor. A brain neuropeptide present in human spinal fluid: studies in depression, schizophrenia, and Alzheimer's disease. Archives of General Psychiatry. 43: 1143-7. PMID 3022663 DOI: 10.1001/archpsyc.1986.01800120029007 |
1 |
|
| 1986 |
Guidotti A, Hanbauer I. Participation of GABA/benzodiazepine receptor system in the adrenal chromaffin cell function. Advances in Biochemical Psychopharmacology. 42: 165-72. PMID 3020895 |
0.52 |
|
| 1986 |
Gray PW, Glaister D, Seeburg PH, Guidotti A, Costa E. Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor. Proceedings of the National Academy of Sciences of the United States of America. 83: 7547-51. PMID 3020548 DOI: 10.1073/pnas.83.19.7547 |
1 |
|
| 1986 |
Nicoletti F, Wroblewski JT, Novelli A, Alho H, Guidotti A, Costa E. The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1905-11. PMID 3016212 |
1 |
|
| 1986 |
Nicoletti F, Wroblewski JT, Novelli A, Guidotti A, Costa E. Excitatory amino acid signal transduction in cerebellar cell cultures. Functional Neurology. 1: 345-9. PMID 2886406 |
1 |
|
| 1986 |
Kataoka Y, Fujimoto M, Alho H, Guidotti A, Geffard M, Kelly GD, Hanbauer I. Intrinsic gamma aminobutyric acid receptors modulate the release of catecholamine from canine adrenal gland in situ. The Journal of Pharmacology and Experimental Therapeutics. 239: 584-90. PMID 2877086 |
0.56 |
|
| 1986 |
Guidotti A, Ferrero P, Fujimoto M, Santi RM, Costa E. Studies on endogenous ligands (endacoids) for the benzodiazepine/beta carboline binding sites. Advances in Biochemical Psychopharmacology. 41: 137-48. PMID 2874693 |
1 |
|
| 1985 |
Mocchetti I, Guidotti A, Schwartz JP, Costa E. Reserpine changes the dynamic state of enkephalin stores in rat striatum and adrenal medulla by different mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 3379-85. PMID 4078631 |
1 |
|
| 1985 |
Gallo V, Wise BC, Vaccarino F, Guidotti A. gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 2432-8. PMID 4032005 |
1 |
|
| 1985 |
Vaccarino F, Tronconi BM, Panula P, Guidotti A, Costa E. GABA-modulin: a synaptosomal basic protein that differs from small myelin basic protein of rat brain. Journal of Neurochemistry. 44: 278-90. PMID 3964832 DOI: 10.1111/j.1471-4159.1985.tb07142.x |
1 |
|
| 1985 |
Alho H, Costa E, Ferrero P, Fujimoto M, Cosenza-Murphy D, Guidotti A. Diazepam-binding inhibitor: a neuropeptide located in selected neuronal populations of rat brain. Science (New York, N.Y.). 229: 179-82. PMID 3892688 |
1 |
|
| 1985 |
Guidotti A, Ferrero P, Costa E. On the brain endocoid for benzodiazepine recognition sites. Progress in Clinical and Biological Research. 192: 477-84. PMID 3001768 |
1 |
|
| 1985 |
Bormann J, Ferrero P, Guidotti A, Costa E. Neuropeptide modulation of GABA receptor C1- channels. Regulatory Peptides. Supplement. 4: 33-8. PMID 2414820 |
1 |
|
| 1985 |
Guidotti A, Ferrero P, Santi MR, Alho H, Vicini S, Costa E. Gamma-aminobutyric acid and chloride channels: regulation by neuropeptides. Regulatory Peptides. Supplement. 4: 172-81. PMID 2414813 |
1 |
|
| 1985 |
Costa E, Guidotti A. Endogenous ligands for benzodiazepine recognition sites. Biochemical Pharmacology. 34: 3399-403. PMID 2413860 DOI: 10.1016/0006-2952(85)90709-9 |
1 |
|
| 1984 |
Saiani L, Kageyama H, Conti-Tronconi BM, Guidotti A. Purification and characterization of a bungarotoxin polypeptide which blocks nicotinic receptor function in primary culture of adrenal chromaffin cells. Molecular Pharmacology. 25: 327-34. PMID 6700579 |
0.36 |
|
| 1984 |
Quach TT, Tang F, Kageyama H, Mocchetti I, Guidotti A, Meek JL, Costa E, Schwartz JP. Enkephalin biosynthesis in adrenal medulla. Modulation of proenkephalin mRNA content of cultured chromaffin cells by 8-bromo-adenosine 3',5'-monophosphate. Molecular Pharmacology. 26: 255-60. PMID 6548292 |
1 |
|
| 1984 |
Wise BC, Guidotti A, Costa E. Regulation of the GABA receptor complex by a phosphorylation mechanism. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 511-9. PMID 6328933 |
1 |
|
| 1984 |
Kataoka Y, Gutman Y, Guidotti A, Panula P, Wroblewski J, Cosenza-Murphy D, Wu JY, Costa E. Intrinsic GABAergic system of adrenal chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 3218-22. PMID 6328506 |
1 |
|
| 1984 |
Kageyama H, Guidotti A. Effect of alpha-bungarotoxin and etorphine on acetylcholine-evoked release of endogenous and radiolabeled catecholamines from primary culture of adrenal chromaffin cells. Journal of Neuroscience Methods. 10: 9-16. PMID 6328131 |
0.36 |
|
| 1984 |
Ferrero P, Guidotti A, Costa E. Increase in the Bmax of gamma-aminobutyric acid-A recognition sites in brain regions of mice receiving diazepam. Proceedings of the National Academy of Sciences of the United States of America. 81: 2247-51. PMID 6326115 |
1 |
|
| 1984 |
Schwartz JP, Quach TT, Tang F, Kageyama H, Guidotti A, Costa E. Cyclic-AMP-mediated modulation of gene expression in adrenal chromaffin cell cultures. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 529-34. PMID 6145331 |
1 |
|
| 1984 |
Ferrero P, Guidotti A, Conti-Tronconi B, Costa E. A brain octadecaneuropeptide generated by tryptic digestion of DBI (diazepam binding inhibitor) functions as a proconflict ligand of benzodiazepine recognition sites. Neuropharmacology. 23: 1359-62. PMID 6098849 |
1 |
|
| 1984 |
Costa E, Ferrari M, Ferrero P, Guidotti A. Multiple signals in GABAergic transmission: pharmacological consequences. Neuropharmacology. 23: 989-91. PMID 6090970 |
1 |
|
| 1984 |
Corda MG, Ferrari M, Guidotti A, Konkel D, Costa E. Isolation, purification and partial sequence of a neuropeptide (diazepam-binding inhibitor) precursor of an anxiogenic putative ligand for benzodiazepine recognition site. Neuroscience Letters. 47: 319-24. PMID 6089051 |
1 |
|
| 1983 |
Costa E, Corda MG, Guidotti A. On a brain polypeptide functioning as a putative effector for the recognition sites of benzodiazepine and beta-carboline derivatives. Neuropharmacology. 22: 1481-92. PMID 6322042 |
1 |
|
| 1983 |
Guidotti A, Corda MG, Wise BC, Vaccarino F, Costa E. GABAergic synapses. Supramolecular organization and biochemical regulation. Neuropharmacology. 22: 1471-9. PMID 6322041 DOI: 10.1016/0028-3908(83)90115-6 |
1 |
|
| 1979 |
Guidotti A, Gale K, Suria A, Toffano G. Biochemical evidence for two classes of GABA receptors in rat brain. Brain Research. 172: 566-71. PMID 224975 |
1 |
|
| 1979 |
Gale K, Moroni F, Kumakura K, Guidotti A. Opiate-receptors in substantia nigra: role in the regulation of striatal tyrosine hydroxylase activity. Neuropharmacology. 18: 427-30. PMID 36574 |
1 |
|
| 1978 |
Guidotti A, Gale K, Toffano G, Vargas FM. Tolerance to tyrosine hydroxylase activation in n. accumbens and c. striatum after repeated injections of "classical" and "atypical" antischizophrenic drugs. Life Sciences. 23: 501-5. PMID 29190 |
1 |
|
| 1978 |
Gale K, Costa E, Toffano G, Hong JS, Guidotti A. Evidence for a role of nigral gamma-aminobutyric acid and substance P in the haloperidol-induced activation of striatal tyrosine hydroxylase. The Journal of Pharmacology and Experimental Therapeutics. 206: 29-37. PMID 26799 |
1 |
|
| 1977 |
Guidotti A, Gale K. Participation of GABA receptors in the short-term activation of striatal tyrosine-3-monooxygenase elicited by neuroleptics. Advances in Biochemical Psychopharmacology. 16: 455-60. PMID 18893 |
1 |
|
| 1977 |
Gale K, Guidotti A, Costa E. Dopamine-sensitive adenylate cyclase: location in substantia nigra. Science (New York, N.Y.). 195: 503-5. PMID 13499 |
1 |
|
| 1976 |
Gale KN, Guidotti A. GABA-mediated control of rat neostriatal tyrosine hydroxylase revealed by intranigral muscimol. Nature. 263: 691-3. PMID 10528 |
1 |
|
| Show low-probability matches. |