Georg Reiser - Publications

Affiliations: 
Institute for Neurobiochemistry, Magdeberg, Magdeburg, Sachsen-Anhalt, Germany 
Area:
Glia

213 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Azarashvili T, Krestinina O, Baburina Y, Odinokova I, Grachev D, Papadopoulos V, Akatov V, Lemasters JJ, Reiser G. Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria. Archives of Biochemistry and Biophysics. 587: 70-7. PMID 26498031 DOI: 10.1016/j.abb.2015.10.012  1
2015 Azran S, Danino O, Förster D, Kenigsberg S, Reiser G, Dixit M, Singh V, Major DT, Fischer B. Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action. Journal of Medicinal Chemistry. PMID 26447940 DOI: 10.1021/acs.jmedchem.5b00575  1
2015 Förster D, Reiser G. Supportive or detrimental roles of P2Y receptors in brain pathology?-The two faces of P2Y receptors in stroke and neurodegeneration detected in neural cell and in animal model studies. Purinergic Signalling. PMID 26407872 DOI: 10.1007/s11302-015-9471-6  1
2015 Baburina Y, Azarashvili T, Grachev D, Krestinina O, Galvita A, Stricker R, Reiser G. Mitochondrial 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) interacts with mPTP modulators and functional complexes (I-V) coupled with release of apoptotic factors. Neurochemistry International. 90: 46-55. PMID 26188334 DOI: 10.1016/j.neuint.2015.07.012  1
2015 Zhu Z, Li R, Stricker R, Reiser G. Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria. Brain Research. PMID 25998538 DOI: 10.1016/j.brainres.2015.05.011  1
2015 Chistyakov DV, Aleshin SE, Astakhova AA, Sergeeva MG, Reiser G. Regulation of peroxisome proliferator-activated receptors (PPAR) α and -γ of rat brain astrocytes in the course of activation by toll-like receptor agonists. Journal of Neurochemistry. 134: 113-24. PMID 25818681 DOI: 10.1111/jnc.13101  1
2015 Kruska N, Schönfeld P, Pujol A, Reiser G. Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions. Biochimica Et Biophysica Acta. 1852: 925-36. PMID 25583114 DOI: 10.1016/j.bbadis.2015.01.005  1
2015 Zhu Z, Stricker R, Li Ry, Zündorf G, Reiser G. The intracellular carboxyl tail of the PAR-2 receptor controls intracellular signaling and cell death. Cell and Tissue Research. 359: 817-27. PMID 25519044 DOI: 10.1007/s00441-014-2056-9  1
2015 Krestinina O, Azarashvili T, Baburina Y, Galvita A, Grachev D, Stricker R, Reiser G. In aging, the vulnerability of rat brain mitochondria is enhanced due to reduced level of 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNP) and subsequently increased permeability transition in brain mitochondria in old animals. Neurochemistry International. 80: 41-50. PMID 25277077 DOI: 10.1016/j.neuint.2014.09.008  1
2014 Zhu Z, Reiser G. Signaling mechanism of protease activated receptor 1-induced proliferation of astrocytes: stabilization of hypoxia inducible factor-1α triggers glucose metabolism and accumulation of cyclin D1. Neurochemistry International. 79: 20-32. PMID 25280834 DOI: 10.1016/j.neuint.2014.09.010  1
2014 Azarashvili T, Baburina Y, Grachev D, Krestinina O, Papadopoulos V, Lemasters JJ, Odinokova I, Reiser G. Carbenoxolone induces permeability transition pore opening in rat mitochondria via the translocator protein TSPO and connexin43. Archives of Biochemistry and Biophysics. 558: 87-94. PMID 24995971 DOI: 10.1016/j.abb.2014.06.027  1
2014 Haas M, Ginsburg-Shmuel T, Fischer B, Reiser G. 5-OMe-uridine-5'-O-(α-boranodiphosphate), a novel nucleotide derivative highly active at the human P2Y(6) receptor protects against death-receptor mediated glial apoptosis. Neuroscience Letters. 578: 80-4. PMID 24970757 DOI: 10.1016/j.neulet.2014.06.030  1
2014 Nordmann C, Strokin M, Schönfeld P, Reiser G. Putative roles of Ca(2+) -independent phospholipase A2 in respiratory chain-associated ROS production in brain mitochondria: influence of docosahexaenoic acid and bromoenol lactone. Journal of Neurochemistry. PMID 24923354 DOI: 10.1111/jnc.12789  1
2014 Stricker R, Reiser G. Functions of the neuron-specific protein ADAP1 (centaurin-α1) in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1. Biological Chemistry. 395: 1321-40. PMID 24854535 DOI: 10.1515/hsz-2014-0107  1
2014 Nadel Y, Lecka J, Gilad Y, Ben-David G, Förster D, Reiser G, Kenigsberg S, Camden J, Weisman GA, Senderowitz H, Sévigny J, Fischer B. Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(α or γ)-thio-(α,β- or β,γ)-methylenetriphosphate scaffold. Journal of Medicinal Chemistry. 57: 4677-91. PMID 24846781 DOI: 10.1021/jm500196c  1
2014 Chistyakov DV, Aleshin S, Sergeeva MG, Reiser G. Regulation of peroxisome proliferator-activated receptor β/δ expression and activity levels by toll-like receptor agonists and MAP kinase inhibitors in rat astrocytes. Journal of Neurochemistry. 130: 563-74. PMID 24806616 DOI: 10.1111/jnc.12757  1
2014 Azarashvili T, Krestinina O, Galvita A, Grachev D, Baburina Y, Stricker R, Reiser G. Identification of phosphorylated form of 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) as 46 kDa phosphoprotein in brain non-synaptic mitochondria overloaded by calcium. Journal of Bioenergetics and Biomembranes. 46: 135-45. PMID 24532135 DOI: 10.1007/s10863-014-9541-4  1
2014 Haas M, Shaaban A, Reiser G. Alanine-(87)-threonine polymorphism impairs signaling and internalization of the human P2Y11 receptor, when co-expressed with the P2Y1 receptor. Journal of Neurochemistry. 129: 602-13. PMID 24524250 DOI: 10.1111/jnc.12666  1
2014 Aleshin S, Reiser G. Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) protects against ceramide-induced cellular toxicity in rat brain astrocytes and neurons by activation of ceramide kinase. Molecular and Cellular Neurosciences. 59: 127-34. PMID 24513118 DOI: 10.1016/j.mcn.2014.01.008  1
2014 Zhu Z, Reiser G. PAR-1 activation rescues astrocytes through the PI3K/Akt signaling pathway from chemically induced apoptosis that is exacerbated by gene silencing of β-arrestin 1. Neurochemistry International. 67: 46-56. PMID 24378649 DOI: 10.1016/j.neuint.2013.12.007  1
2014 Bernstein HG, Steiner J, Bogerts B, Stricker R, Reiser G. Nardilysin, ADAM10, and Alzheimer's disease: of mice and men. Neurobiology of Aging. 35: e1. PMID 24099785 DOI: 10.1016/j.neurobiolaging.2013.08.028  1
2014 Ivanova AE, Gorbacheva LR, Strukova SM, Pinelis VG, Reiser G. Activated protein C and thrombin participate in the regulation of astrocyte functions Biochemistry (Moscow) Supplement Series a: Membrane and Cell Biology. 8: 50-59. DOI: 10.1134/S1990747813050048  1
2013 Aleshin S, Reiser G. Role of the peroxisome proliferator-activated receptors (PPAR)-α, β/δ and γ triad in regulation of reactive oxygen species signaling in brain. Biological Chemistry. 394: 1553-70. PMID 24021597 DOI: 10.1515/hsz-2013-0215  1
2013 Schönfeld P, Reiser G. Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1493-9. PMID 23921897 DOI: 10.1038/jcbfm.2013.128  1
2013 Aleshin S, Strokin M, Sergeeva M, Reiser G. Peroxisome proliferator-activated receptor (PPAR)β/δ, a possible nexus of PPARα- and PPARγ-dependent molecular pathways in neurodegenerative diseases: Review and novel hypotheses. Neurochemistry International. 63: 322-30. PMID 23811400 DOI: 10.1016/j.neuint.2013.06.012  1
2013 Haas M, Ben-Moshe I, Fischer B, Reiser G. Sp-2-propylthio-ATP-α-B and Sp-2-propylthio-ATP-α-B,β-γ-dichloromethylene are novel potent and specific agonists of the human P2Y₁₁ receptor. Biochemical Pharmacology. 86: 645-55. PMID 23810430 DOI: 10.1016/j.bcp.2013.06.013  1
2013 Azran S, Förster D, Danino O, Nadel Y, Reiser G, Fischer B. Highly efficient biocompatible neuroprotectants with dual activity as antioxidants and P2Y receptor agonists. Journal of Medicinal Chemistry. 56: 4938-52. PMID 23751098 DOI: 10.1021/jm400197m  1
2013 Gorbacheva L, Strukova S, Pinelis V, Ishiwata S, Stricker R, Reiser G. NF-κB-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity. Neurochemistry International. 63: 101-11. PMID 23727063 DOI: 10.1016/j.neuint.2013.05.008  1
2013 Bernstein HG, Stricker R, Dobrowolny H, Steiner J, Bogerts B, Trübner K, Reiser G. Nardilysin in human brain diseases: both friend and foe. Amino Acids. 45: 269-78. PMID 23604405 DOI: 10.1007/s00726-013-1499-8  1
2013 Bernstein HG, Stricker R, Zschiebsch K, Müller S, Dobrowolny H, Steiner J, Bogerts B, Reiser G. Decreased expression of nardilysin in SH-SY5Y cells under ethanol stress and reduced density of nardilysin-expressing neurons in brains of alcoholics. Journal of Psychiatric Research. 47: 343-9. PMID 23219461 DOI: 10.1016/j.jpsychires.2012.11.006  1
2013 Ivanova AE, Gorbacheva LR, Strukova SM, Pinelis VG, Reiser G. Activated protein C and thrombin participate in regulation of astrocyte functions Biologicheskie Membrany. 30: 387-397. DOI: 10.7868/S0233475513050046  1
2012 Ginsburg-Shmuel T, Haas M, Grbic D, Arguin G, Nadel Y, Gendron FP, Reiser G, Fischer B. UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety. Bioorganic & Medicinal Chemistry. 20: 5483-95. PMID 22901672 DOI: 10.1016/j.bmc.2012.07.042  1
2012 Strokin M, Seburn KL, Cox GA, Martens KA, Reiser G. Severe disturbance in the Ca2+ signaling in astrocytes from mouse models of human infantile neuroaxonal dystrophy with mutated Pla2g6. Human Molecular Genetics. 21: 2807-14. PMID 22442204 DOI: 10.1093/hmg/dds108  1
2012 Li R, Zhu Z, Reiser G. Specific phosphorylation of αA-crystallin is required for the αA-crystallin-induced protection of astrocytes against staurosporine and C2-ceramide toxicity. Neurochemistry International. 60: 652-8. PMID 22414529 DOI: 10.1016/j.neuint.2012.02.031  1
2012 Haase A, Rott S, Mantion A, Graf P, Plendl J, Thünemann AF, Meier WP, Taubert A, Luch A, Reiser G. Effects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responses. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 457-68. PMID 22240980 DOI: 10.1093/toxsci/kfs003  1
2012 Sokolova E, Aleshin S, Reiser G. Expression of protease-activated receptor (PAR)-2, but not other PARs, is regulated by inflammatory cytokines in rat astrocytes. Neurochemistry International. 60: 276-85. PMID 22227167 DOI: 10.1016/j.neuint.2011.12.016  1
2012 Gorbacheva LR, Pinelis VG, Reiser G, Strukova SM. Activated protein C is the regulator of the NF-κB activity under the conditions of glutamate toxicity Biochemistry (Moscow) Supplement Series a: Membrane and Cell Biology. 6: 56-66. DOI: 10.1134/S1990747811060067  1
2011 Zündorf G, Reiser G. The phosphorylation status of extracellular-regulated kinase 1/2 in astrocytes and neurons from rat hippocampus determines the thrombin-induced calcium release and ROS generation. Journal of Neurochemistry. 119: 1194-204. PMID 21988180 DOI: 10.1111/j.1471-4159.2011.07527.x  1
2011 Borrmann C, Stricker R, Reiser G. Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-α1 (ADAP1). Cell and Tissue Research. 346: 89-98. PMID 21972134 DOI: 10.1007/s00441-011-1245-z  1
2011 Borrmann C, Stricker R, Reiser G. Retinoic acid-induced upregulation of the metalloendopeptidase nardilysin is accelerated by co-expression of the brain-specific protein p42(IP4) (centaurin α 1; ADAP1) in neuroblastoma cells. Neurochemistry International. 59: 936-44. PMID 21801775 DOI: 10.1016/j.neuint.2011.07.004  1
2011 Li R, Reiser G. Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death. Journal of Neurochemistry. 118: 354-64. PMID 21615407 DOI: 10.1111/j.1471-4159.2011.07317.x  1
2011 Kruska N, Reiser G. Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. Neurobiology of Disease. 43: 465-72. PMID 21570468 DOI: 10.1016/j.nbd.2011.04.020  1
2011 Schönfeld P, Schlüter T, Fischer KD, Reiser G. Non-esterified polyunsaturated fatty acids distinctly modulate the mitochondrial and cellular ROS production in normoxia and hypoxia. Journal of Neurochemistry. 118: 69-78. PMID 21517851 DOI: 10.1111/j.1471-4159.2011.07286.x  1
2011 Boltze J, Kranz A, Wagner DC, Reymann K, Reiser G, Hess DC. Recent advances in basic and translational stroke research. Expert Review of Neurotherapeutics. 11: 199-202. PMID 21306206 DOI: 10.1586/ern.10.202  1
2011 Luo W, Wang Y, Reiser G. Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking. Journal of Neurochemistry. 117: 71-81. PMID 21219331 DOI: 10.1111/j.1471-4159.2011.07173.x  1
2011 Strokin M, Sergeeva M, Reiser G. Proinflammatory treatment of astrocytes with lipopolysaccharide results in augmented Ca2+ signaling through increased expression of via phospholipase A2 (iPLA2). American Journal of Physiology. Cell Physiology. 300: C542-9. PMID 21178110 DOI: 10.1152/ajpcell.00428.2010  1
2011 Azarashvili T, Baburina Y, Grachev D, Krestinina O, Evtodienko Y, Stricker R, Reiser G. Calcium-induced permeability transition in rat brain mitochondria is promoted by carbenoxolone through targeting connexin43. American Journal of Physiology. Cell Physiology. 300: C707-20. PMID 21148408 DOI: 10.1152/ajpcell.00061.2010  1
2011 Zündorf G, Reiser G. Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection. Antioxidants & Redox Signaling. 14: 1275-88. PMID 20615073 DOI: 10.1089/ars.2010.3359  1
2011 Rönicke R, Mikhaylova M, Rönicke S, Meinhardt J, Schröder UH, Fändrich M, Reiser G, Kreutz MR, Reymann KG. Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors. Neurobiology of Aging. 32: 2219-28. PMID 20133015 DOI: 10.1016/j.neurobiolaging.2010.01.011  1
2010 Eliahu S, Lecka J, Reiser G, Haas M, Bigonnesse F, Lévesque SA, Pelletier J, Sévigny J, Fischer B. Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors. Journal of Medicinal Chemistry. 53: 8485-97. PMID 21090681 DOI: 10.1021/jm100597c  1
2010 Sergeeva MG, Aleshin SE, Grabeklis S, Reiser G. PPAR activation has dichotomous control on the expression levels of cytosolic and secretory phospholipase A2 in astrocytes; inhibition in naïve, untreated cells and enhancement in LPS-stimulated cells. Journal of Neurochemistry. 115: 399-410. PMID 20670373 DOI: 10.1111/j.1471-4159.2010.06931.x  1
2010 Azarashvili T, Stricker R, Reiser G. The mitochondria permeability transition pore complex in the brain with interacting proteins - promising targets for protection in neurodegenerative diseases. Biological Chemistry. 391: 619-29. PMID 20370325 DOI: 10.1515/BC.2010.070  1
2010 Ginsburg-Shmuel T, Haas M, Schumann M, Reiser G, Kalid O, Stern N, Fischer B. 5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist. Journal of Medicinal Chemistry. 53: 1673-85. PMID 20095577 DOI: 10.1021/jm901450d  1
2010 Gorbacheva L, Pinelis V, Ishiwata S, Strukova S, Reiser G. Activated protein C prevents glutamate- and thrombin-induced activation of nuclear factor-kappaB in cultured hippocampal neurons. Neuroscience. 165: 1138-46. PMID 19931359 DOI: 10.1016/j.neuroscience.2009.11.027  1
2010 Henrich-Noack P, Riek-Burchardt M, Reymann KG, Reiser G. Cellular expression pattern of the protease-activated receptor 4 in the hippocampus in naïve rats and after global ischaemia. Journal of Neuroscience Research. 88: 850-7. PMID 19859967 DOI: 10.1002/jnr.22261  1
2010 Grachev DE, Krestinina OV, Baburina YL, Reiser G, Azarashvili TS. Effect of Ro 5-4864 and PK11195 on protein phosphorylation in mitochondria isolated from primary cultures of rat astrocytes Biochemistry (Moscow) Supplement Series a: Membrane and Cell Biology. 4: 43-49. DOI: 10.1134/S1990747810010071  1
2010 Grachev DE, Krestinina OV, Baburina YL, Reiser G, Azarashvili TS. Effects of Ro 5-4864 and PK11195 on protein phosphorylation in mitochondria isolated from astrocytes in primary culture Biologicheskie Membrany. 27: 52-59.  1
2009 Schönfeld P, Kruska N, Reiser G. Antioxidative activity of the olive oil constituent hydroxy-1-aryl-isochromans in cells and cell-free systems. Biochimica Et Biophysica Acta. 1790: 1698-704. PMID 19800396 DOI: 10.1016/j.bbagen.2009.09.008  1
2009 Gorbacheva L, Davidova O, Sokolova E, Ishiwata S, Pinelis V, Strukova S, Reiser G. Endothelial protein C receptor is expressed in rat cortical and hippocampal neurons and is necessary for protective effect of activated protein C at glutamate excitotoxicity. Journal of Neurochemistry. 111: 967-75. PMID 19780891 DOI: 10.1111/j.1471-4159.2009.06380.x  1
2009 Rönicke S, Kruska N, Kahlert S, Reiser G. The influence of the branched-chain fatty acids pristanic acid and Refsum disease-associated phytanic acid on mitochondrial functions and calcium regulation of hippocampal neurons, astrocytes, and oligodendrocytes. Neurobiology of Disease. 36: 401-10. PMID 19703563 DOI: 10.1016/j.nbd.2009.08.005  1
2009 Li R, Rohatgi T, Hanck T, Reiser G. Alpha A-crystallin and alpha B-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death. Journal of Neurochemistry. 110: 1433-44. PMID 19558454 DOI: 10.1111/j.1471-4159.2009.06226.x  1
2009 Aleshin S, Grabeklis S, Hanck T, Sergeeva M, Reiser G. Peroxisome proliferator-activated receptor (PPAR)-gamma positively controls and PPARalpha negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPARbeta/delta via mutual control of PPAR expression levels. Molecular Pharmacology. 76: 414-24. PMID 19483106 DOI: 10.1124/mol.109.056010  1
2009 Krestinina OV, Grachev DE, Odinokova IV, Reiser G, Evtodienko YV, Azarashvili TS. Effect of peripheral benzodiazepine receptor (PBR/TSPO) ligands on opening of Ca2+-induced pore and phosphorylation of 3.5-kDa polypeptide in rat brain mitochondria. Biochemistry. BiokhimiiÍ¡A. 74: 421-9. PMID 19463096 DOI: 10.1134/S0006297909040105  1
2009 Galvita A, Grachev D, Azarashvili T, Baburina Y, Krestinina O, Stricker R, Reiser G. The brain-specific protein, p42(IP4) (ADAP 1) is localized in mitochondria and involved in regulation of mitochondrial Ca2+. Journal of Neurochemistry. 109: 1701-13. PMID 19383085 DOI: 10.1111/j.1471-4159.2009.06089.x  1
2009 Azarashvili T, Krestinina O, Galvita A, Grachev D, Baburina Y, Stricker R, Evtodienko Y, Reiser G. Ca2+-dependent permeability transition regulation in rat brain mitochondria by 2',3'-cyclic nucleotides and 2',3'-cyclic nucleotide 3'-phosphodiesterase. American Journal of Physiology. Cell Physiology. 296: C1428-39. PMID 19357238 DOI: 10.1152/ajpcell.00006.2009  1
2009 Reiser G, Reymann K. Cerebral ischemia and stroke--highlights of the 5th International Symposium on Neuroprotection and Neurorepair in Magdeburg, Germany, May 17-20, 2008. Restorative Neurology and Neuroscience. 27: 79-81. PMID 19289860 DOI: 10.3233/RNN-2009-0463  1
2009 Bernstein HG, Stricker R, Lendeckel U, Bertram I, Dobrowolny H, Steiner J, Bogerts B, Reiser G. Reduced neuronal co-localisation of nardilysin and the putative alpha-secretases ADAM10 and ADAM17 in Alzheimer's disease and Down syndrome brains. Age (Dordrecht, Netherlands). 31: 11-25. PMID 19234765 DOI: 10.1007/s11357-008-9076-x  1
2009 Zündorf G, Kahlert S, Bunik VI, Reiser G. alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ. Neuroscience. 158: 610-6. PMID 18996448 DOI: 10.1016/j.neuroscience.2008.10.015  1
2009 Graf A, Kabysheva M, Klimuk E, Trofimova L, Dunaeva T, Zündorf G, Kahlert S, Reiser G, Storozhevykh T, Pinelis V, Sokolova N, Bunik V. Role of 2-oxoglutarate dehydrogenase in brain pathologies involving glutamate neurotoxicity Journal of Molecular Catalysis B: Enzymatic. 61: 80-87. DOI: 10.1016/j.molcatb.2009.02.016  1
2009 Luo W, Wang Y, Reiser G. The role of thrombin and thrombin receptors in the brain Thrombin: Physiology and Disease. 133-159. DOI: 10.1007/978-0-387-09637-7_8  1
2008 Sokolova E, Reiser G. Prothrombin/thrombin and the thrombin receptors PAR-1 and PAR-4 in the brain: localization, expression and participation in neurodegenerative diseases. Thrombosis and Haemostasis. 100: 576-81. PMID 18841278 DOI: 10.1160/TH08-03-0131  1
2008 Ecke D, Fischer B, Reiser G. Diastereoselectivity of the P2Y11 nucleotide receptor: mutational analysis. British Journal of Pharmacology. 155: 1250-5. PMID 18820714 DOI: 10.1038/bjp.2008.352  1
2008 Bunik V, Kaehne T, Degtyarev D, Shcherbakova T, Reiser G. Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart. The Febs Journal. 275: 4990-5006. PMID 18783430 DOI: 10.1111/j.1742-4658.2008.06632.x  1
2008 Schönfeld P, Reiser G. Comment concerning the article: 'Phytanic acid impairs mitochondrial respiration through protonophoric action' by Komen et al.: branched chain phytanic acid inhibits the activity of the mitochondrial respiratory chain. Cellular and Molecular Life Sciences : Cmls. 65: 2266-9. PMID 18581054 DOI: 10.1007/s00018-008-8117-z  1
2008 Sokolova E, Hartig R, Reiser G. Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E receptor EP2 through cAMP elevation and protein kinase A. The Febs Journal. 275: 3669-79. PMID 18537828 DOI: 10.1111/j.1742-4658.2008.06511.x  1
2008 Kahlert S, Zündorf G, Reiser G. Detection of de- and hyperpolarization of mitochondria of cultured astrocytes and neurons by the cationic fluorescent dye rhodamine 123. Journal of Neuroscience Methods. 171: 87-92. PMID 18400303 DOI: 10.1016/j.jneumeth.2008.02.015  1
2008 Hein S, Schönfeld P, Kahlert S, Reiser G. Toxic effects of X-linked adrenoleukodystrophy-associated, very long chain fatty acids on glial cells and neurons from rat hippocampus in culture. Human Molecular Genetics. 17: 1750-61. PMID 18344355 DOI: 10.1093/hmg/ddn066  1
2008 Haase A, Nordmann C, Sedehizade F, Borrmann C, Reiser G. RanBPM, a novel interaction partner of the brain-specific protein p42IP4/centaurin alpha-1. Journal of Neurochemistry. 105: 2237-48. PMID 18298663 DOI: 10.1111/j.1471-4159.2008.05308.x  1
2008 Ostrowska E, Reiser G. The protease-activated receptor-3 (PAR-3) can signal autonomously to induce interleukin-8 release. Cellular and Molecular Life Sciences : Cmls. 65: 970-81. PMID 18264801 DOI: 10.1007/s00018-008-7555-y  1
2008 Henrich-Noack P, Baldauf K, Reiser G, Reymann KG. Pattern of time-dependent reduction of histologically determined infarct volume after focal ischaemia in mice. Neuroscience Letters. 432: 141-5. PMID 18222610 DOI: 10.1016/j.neulet.2007.12.029  1
2008 Ostrowska E, Reiser G. Protease-activated receptor (PAR)-induced interleukin-8 production in airway epithelial cells requires activation of MAP kinases p44/42 and JNK. Biochemical and Biophysical Research Communications. 366: 1030-5. PMID 18086557 DOI: 10.1016/j.bbrc.2007.12.064  1
2008 Wang Y, Luo W, Reiser G. Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions. Cellular and Molecular Life Sciences : Cmls. 65: 237-52. PMID 17965832 DOI: 10.1007/s00018-007-7288-3  1
2008 Ecke D, Hanck T, Tulapurkar ME, Schäfer R, Kassack M, Stricker R, Reiser G. Hetero-oligomerization of the P2Y11 receptor with the P2Y1 receptor controls the internalization and ligand selectivity of the P2Y11 receptor. The Biochemical Journal. 409: 107-16. PMID 17824841 DOI: 10.1042/BJ20070671  1
2008 Grishina ZV, Pushkareva MA, Pletjushkina OY, Reiser G, Peters-Golden M, Sud'ina GF. Sulfatides inhibit leukotriene synthesis in human polymorphonuclear granulocytes by a mechanism involving lipid rearrangement in intracellular membranes. The International Journal of Biochemistry & Cell Biology. 40: 110-24. PMID 17822942 DOI: 10.1016/j.biocel.2007.07.001  1
2007 Wang Y, Luo W, Reiser G. Activation of protease-activated receptors in astrocytes evokes a novel neuroprotective pathway through release of chemokines of the growth-regulated oncogene/cytokine-induced neutrophil chemoattractant family. The European Journal of Neuroscience. 26: 3159-68. PMID 18005059 DOI: 10.1111/j.1460-9568.2007.05938.x  1
2007 Luo W, Wang Y, Reiser G. Protease-activated receptors in the brain: receptor expression, activation, and functions in neurodegeneration and neuroprotection. Brain Research Reviews. 56: 331-45. PMID 17915333 DOI: 10.1016/j.brainresrev.2007.08.002  1
2007 Ostrowska E, Sokolova E, Reiser G. PAR-2 activation and LPS synergistically enhance inflammatory signaling in airway epithelial cells by raising PAR expression level and interleukin-8 release. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L1208-18. PMID 17766588 DOI: 10.1152/ajplung.00137.2007  1
2007 Luo W, Wang Y, Reiser G. p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking. The Journal of Biological Chemistry. 282: 30246-55. PMID 17693410 DOI: 10.1074/jbc.M703205200  1
2007 Wang Y, Luo W, Reiser G. The role of calcium in protease-activated receptor-induced secretion of chemokine GRO/CINC-1 in rat brain astrocytes. Journal of Neurochemistry. 103: 814-9. PMID 17666044 DOI: 10.1111/j.1471-4159.2007.04803.x  1
2007 Strokin M, Sergeeva M, Reiser G. Prostaglandin synthesis in rat brain astrocytes is under the control of the n-3 docosahexaenoic acid, released by group VIB calcium-independent phospholipase A2. Journal of Neurochemistry. 102: 1771-82. PMID 17555549 DOI: 10.1111/j.1471-4159.2007.04663.x  1
2007 Sokolova E, Reiser G. A novel therapeutic target in various lung diseases: airway proteases and protease-activated receptors. Pharmacology & Therapeutics. 115: 70-83. PMID 17532472 DOI: 10.1016/j.pharmthera.2007.04.002  1
2007 Kahlert S, Blaser T, Tulapurkar M, Reiser G. P2Y receptor-activating nucleotides modulate cellular reactive oxygen species production in dissociated hippocampal astrocytes and neurons in culture independent of parallel cytosolic Ca(2+) rise and change in mitochondrial potential. Journal of Neuroscience Research. 85: 3443-56. PMID 17492786 DOI: 10.1002/jnr.21316  1
2007 Bernstein HG, Stricker R, Dobrowolny H, Trübner K, Bogerts B, Reiser G. Histochemical evidence for wide expression of the metalloendopeptidase nardilysin in human brain neurons. Neuroscience. 146: 1513-23. PMID 17442499 DOI: 10.1016/j.neuroscience.2007.02.057  1
2007 Zündorf G, Kahlert S, Reiser G. Gap-junction blocker carbenoxolone differentially enhances NMDA-induced cell death in hippocampal neurons and astrocytes in co-culture. Journal of Neurochemistry. 102: 508-21. PMID 17403140 DOI: 10.1111/j.1471-4159.2007.04509.x  1
2007 Zylberg J, Ecke D, Fischer B, Reiser G. Structure and ligand-binding site characteristics of the human P2Y11 nucleotide receptor deduced from computational modelling and mutational analysis. The Biochemical Journal. 405: 277-86. PMID 17338680 DOI: 10.1042/BJ20061728  1
2007 Laskowski A, Reiser G, Reymann KG. Protease-activated receptor-1 induces generation of new microglia in the dentate gyrus of traumatised hippocampal slice cultures. Neuroscience Letters. 415: 17-21. PMID 17324513 DOI: 10.1016/j.neulet.2006.12.050  1
2007 Azarashvili T, Grachev D, Krestinina O, Evtodienko Y, Yurkov I, Papadopoulos V, Reiser G. The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria. Cell Calcium. 42: 27-39. PMID 17174393 DOI: 10.1016/j.ceca.2006.11.004  1
2007 Schönfeld P, Reiser G. Ca2+ storage capacity of rat brain mitochondria declines during the postnatal development without change in ROS production capacity. Antioxidants & Redox Signaling. 9: 191-9. PMID 17115935 DOI: 10.1089/ars.2007.9.ft-4  1
2007 Wang Y, Luo W, Reiser G. Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain. The Biochemical Journal. 401: 65-78. PMID 16942465 DOI: 10.1042/BJ20060732  1
2007 Herrmann C, Frankenberger J, Reiser G, Lamotte J. Optimization of a CR system comprising line-scanning and needle image plate technology with respect to examinations of extremities Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6510. DOI: 10.1117/12.708368  1
2006 Ecke D, Tulapurkar ME, Nahum V, Fischer B, Reiser G. Opposite diastereoselective activation of P2Y1 and P2Y11 nucleotide receptors by adenosine 5'-O-(alpha-boranotriphosphate) analogues. British Journal of Pharmacology. 149: 416-23. PMID 16953187 DOI: 10.1038/sj.bjp.0706887  1
2006 Schäfer R, Hartig R, Sedehizade F, Welte T, Reiser G. Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kappaB1 and mitogen-activated protein kinase pathways. The Febs Journal. 273: 3756-67. PMID 16911524 DOI: 10.1111/j.1742-4658.2006.05384.x  1
2006 Wang Y, Luo W, Wartmann T, Halangk W, Sahin-Tóth M, Reiser G. Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes. Journal of Neurochemistry. 99: 759-69. PMID 16903872 DOI: 10.1111/j.1471-4159.2006.04105.x  1
2006 Sharon E, Lévesque SA, Munkonda MN, Sévigny J, Ecke D, Reiser G, Fischer B. Fluorescent N2,N3-epsilon-adenine nucleoside and nucleotide probes: synthesis, spectroscopic properties, and biochemical evaluation. Chembiochem : a European Journal of Chemical Biology. 7: 1361-74. PMID 16871613 DOI: 10.1002/cbic.200600070  1
2006 Laubinger W, Tulapurkar ME, Schäfer R, Reiser G. Distinct mono- and dinucleotide-specific P2Y receptors in A549 lung epithelial cells: different control of arachidonic acid release and nitric oxide synthase expression. European Journal of Pharmacology. 543: 1-7. PMID 16844112 DOI: 10.1016/j.ejphar.2006.06.029  1
2006 Stricker R, Chow KM, Walther D, Hanck T, Hersh LB, Reiser G. Interaction of the brain-specific protein p42IP4/centaurin-alpha1 with the peptidase nardilysin is regulated by the cognate ligands of p42IP4, PtdIns(3,4,5)P3 and Ins(1,3,4,5)P4, with stereospecificity. Journal of Neurochemistry. 98: 343-54. PMID 16805830 DOI: 10.1111/j.1471-4159.2006.03869.x  1
2006 Wang Y, Luo W, Stricker R, Reiser G. Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1. Journal of Neurochemistry. 98: 1046-60. PMID 16749907 DOI: 10.1111/j.1471-4159.2006.03950.x  1
2006 Bunik VI, Raddatz G, Wanders RJ, Reiser G. Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid. Febs Letters. 580: 3551-7. PMID 16737698 DOI: 10.1016/j.febslet.2006.05.040  1
2006 Schönfeld P, Kahlert S, Reiser G. A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes. Experimental Gerontology. 41: 688-96. PMID 16616447 DOI: 10.1016/j.exger.2006.02.013  1
2006 Strokin M, Chechneva O, Reymann KG, Reiser G. Neuroprotection of rat hippocampal slices exposed to oxygen-glucose deprivation by enrichment with docosahexaenoic acid and by inhibition of hydrolysis of docosahexaenoic acid-containing phospholipids by calcium independent phospholipase A2. Neuroscience. 140: 547-53. PMID 16563639 DOI: 10.1016/j.neuroscience.2006.02.026  1
2006 Nahum V, Tulapurkar M, Lévesque SA, Sévigny J, Reiser G, Fischer B. Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors. Journal of Medicinal Chemistry. 49: 1980-90. PMID 16539385 DOI: 10.1021/jm050955y  1
2006 Luo W, Wang Y, Hanck T, Stricker R, Reiser G. Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1. The Journal of Biological Chemistry. 281: 7927-36. PMID 16410250 DOI: 10.1074/jbc.M510784200  1
2006 Schönfeld P, Reiser G. Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria. The Journal of Biological Chemistry. 281: 7136-42. PMID 16410242 DOI: 10.1074/jbc.M513198200  1
2006 Tulapurkar ME, Zündorf G, Reiser G. Internalization and desensitization of a green fluorescent protein-tagged P2Y nucleotide receptor are differently controlled by inhibition of calmodulin-dependent protein kinase II. Journal of Neurochemistry. 96: 624-34. PMID 16405509 DOI: 10.1111/j.1471-4159.2005.03594.x  1
2006 Henrich-Noack P, Riek-Burchardt M, Baldauf K, Reiser G, Reymann KG. Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra. Brain Research. 1070: 232-41. PMID 16403464 DOI: 10.1016/j.brainres.2005.10.100  1
2006 Henrich-Noack P, Striggow F, Reiser G, Reymann KG. Preconditioning with thrombin can be protective or worsen damage after endothelin-1-induced focal ischemia in rats. Journal of Neuroscience Research. 83: 469-75. PMID 16397902 DOI: 10.1002/jnr.20746  1
2006 Reiser G, Schönfeld P, Kahlert S. Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 24: 113-22. PMID 16386870 DOI: 10.1016/j.ijdevneu.2005.11.002  1
2006 Reiser G, Schild L, Kahlert S. Effect of excitotoxicity and experimental ischemia on mitochondria in neurons and astrocytes: Targets for neuroprotection International Journal of Neuroprotection and Neuroregeneration. 2: 103-109.  1
2005 Sedehizade F, von Klot C, Hanck T, Reiser G. p42(IP4)/centaurin alpha1, a brain-specific PtdIns(3,4,5)P3/Ins(1,3,4,5)P4-binding protein: membrane trafficking induced by epidermal growth factor is inhibited by stimulation of phospholipase C-coupled thrombin receptor. Neurochemical Research. 30: 1319-30. PMID 16341594 DOI: 10.1007/s11064-005-8804-1  1
2005 Schild L, Plumeyer F, Reiser G. Ca(2+) rise within a narrow window of concentration prevents functional injury of mitochondria exposed to hypoxia/reoxygenation by increasing antioxidative defence. The Febs Journal. 272: 5844-52. PMID 16279948 DOI: 10.1111/j.1742-4658.2005.04978.x  1
2005 Grishina Z, Ostrowska E, Halangk W, Sahin-Tóth M, Reiser G. Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1. British Journal of Pharmacology. 146: 990-9. PMID 16231009 DOI: 10.1038/sj.bjp.0706410  1
2005 Sergeeva M, Strokin M, Reiser G. Regulation of intracellular calcium levels by polyunsaturated fatty acids, arachidonic acid and docosahexaenoic acid, in astrocytes: possible involvement of phospholipase A2. Reproduction, Nutrition, Development. 45: 633-46. PMID 16188212 DOI: 10.1051/rnd:2005050  1
2005 Azarashvili T, Krestinina O, Yurkov I, Evtodienko Y, Reiser G. High-affinity peripheral benzodiazepine receptor ligand, PK11195, regulates protein phosphorylation in rat brain mitochondria under control of Ca(2+). Journal of Neurochemistry. 94: 1054-62. PMID 16092946 DOI: 10.1111/j.1471-4159.2005.03260.x  1
2005 Schild L, Reiser G. Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+. The Febs Journal. 272: 3593-601. PMID 16008559 DOI: 10.1111/j.1742-4658.2005.04781.x  1
2005 Tulapurkar ME, Schäfer R, Hanck T, Flores RV, Weisman GA, González FA, Reiser G. Endocytosis mechanism of P2Y2 nucleotide receptor tagged with green fluorescent protein: clathrin and actin cytoskeleton dependence. Cellular and Molecular Life Sciences : Cmls. 62: 1388-99. PMID 15924261 DOI: 10.1007/s00018-005-5052-0  1
2005 Luo W, Wang Y, Reiser G. Two types of protease-activated receptors (PAR-1 and PAR-2) mediate calcium signaling in rat retinal ganglion cells RGC-5. Brain Research. 1047: 159-67. PMID 15907810 DOI: 10.1016/j.brainres.2005.04.040  1
2005 Kahlert S, Schönfeld P, Reiser G. The Refsum disease marker phytanic acid, a branched chain fatty acid, affects Ca2+ homeostasis and mitochondria, and reduces cell viability in rat hippocampal astrocytes. Neurobiology of Disease. 18: 110-8. PMID 15649701 DOI: 10.1016/j.nbd.2004.08.010  1
2005 Kahlert S, Zündorf G, Reiser G. Glutamate-mediated influx of extracellular Ca2+ is coupled with reactive oxygen species generation in cultured hippocampal neurons but not in astrocytes. Journal of Neuroscience Research. 79: 262-71. PMID 15578732 DOI: 10.1002/jnr.20322  1
2005 Sokolova E, Grishina Z, Bühling F, Welte T, Reiser G. Protease-activated receptor-1 in human lung fibroblasts mediates a negative feedback downregulation via prostaglandin E2. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L793-802. PMID 15563688 DOI: 10.1152/ajplung.00343.2004  1
2004 Rohatgi T, Sedehizade F, Reymann KG, Reiser G. Protease-activated receptors in neuronal development, neurodegeneration, and neuroprotection: thrombin as signaling molecule in the brain. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10: 501-12. PMID 15534036 DOI: 10.1177/1073858404269955  1
2004 Sharon E, Zündorf G, Lévesque SA, Beaudoin AR, Reiser G, Fischer B. Fluorescent epsilon-ATP analogues for probing physicochemical properties of proteins. Synthesis, biochemical evaluation, and sensitivity to properties of the medium. Bioorganic & Medicinal Chemistry. 12: 6119-35. PMID 15519157 DOI: 10.1016/j.bmc.2004.09.011  1
2004 Strokin M, Sergeeva M, Reiser G. Role of Ca2+-independent phospholipase A2 and n-3 polyunsaturated fatty acid docosahexaenoic acid in prostanoid production in brain: perspectives for protection in neuroinflammation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 22: 551-7. PMID 15465285 DOI: 10.1016/j.ijdevneu.2004.07.002  1
2004 Martínez-Sánchez M, Striggow F, Schröder UH, Kahlert S, Reymann KG, Reiser G. Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures. Neuroscience. 128: 729-40. PMID 15464281 DOI: 10.1016/j.neuroscience.2004.06.074  1
2004 Major DT, Nahum V, Wang Y, Reiser G, Fischer B. Molecular recognition in purinergic receptors. 2. Diastereoselectivity of the h-P2Y1-receptor. Journal of Medicinal Chemistry. 47: 4405-16. PMID 15317453 DOI: 10.1021/jm049771u  1
2004 Kahlert S, Reiser G. Glial perspectives of metabolic states during cerebral hypoxia--calcium regulation and metabolic energy. Cell Calcium. 36: 295-302. PMID 15261485 DOI: 10.1016/j.ceca.2004.02.009  1
2004 Schönfeld P, Kahlert S, Reiser G. In brain mitochondria the branched-chain fatty acid phytanic acid impairs energy transduction and sensitizes for permeability transition. The Biochemical Journal. 383: 121-8. PMID 15198638 DOI: 10.1042/BJ20040583  1
2004 Tulapurkar ME, Laubinger W, Nahum V, Fischer B, Reiser G. Subtype specific internalization of P2Y1 and P2Y2 receptors induced by novel adenosine 5'-O-(1-boranotriphosphate) derivatives. British Journal of Pharmacology. 142: 869-78. PMID 15197109 DOI: 10.1038/sj.bjp.0705859  1
2004 Wang Y, Richter-Landsberg C, Reiser G. Expression of protease-activated receptors (PARs) in OLN-93 oligodendroglial cells and mechanism of PAR-1-induced calcium signaling. Neuroscience. 126: 69-82. PMID 15145074 DOI: 10.1016/j.neuroscience.2004.03.024  1
2004 Reiser G, Bernstein HG. Altered expression of protein p42IP4/centaurin-alpha 1 in Alzheimer's disease brains and possible interaction of p42IP4 with nucleolin. Neuroreport. 15: 147-8. PMID 15106847 DOI: 10.1097/00001756-200401190-00028  1
2004 Reiser G, Striggow F, Hackmann C, Schwegler H, Yilmazer-Hanke DM. Short-term down-regulation of the brain-specific, PtdIns(3,4,5)P3/Ins(1,3,4,5)P4-binding, adapter protein, p42IP4/centaurin-alpha 1 in rat brain after acoustic and electric stimulation. Neurochemistry International. 45: 89-93. PMID 15082226 DOI: 10.1016/j.neuint.2003.12.003  1
2004 Rohatgi T, Henrich-Noack P, Sedehizade F, Goertler M, Wallesch CW, Reymann KG, Reiser G. Transient focal ischemia in rat brain differentially regulates mRNA expression of protease-activated receptors 1 to 4. Journal of Neuroscience Research. 75: 273-9. PMID 14705148 DOI: 10.1002/jnr.10847  1
2004 Hanck T, Stricker R, Sedehizade F, Reiser G. Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins. Journal of Neurochemistry. 88: 326-36. PMID 14690521  1
2003 Stricker R, Vandekerckhove J, Krishna MU, Falck JR, Hanck T, Reiser G. Oligomerization controls in tissue-specific manner ligand binding of native, affinity-purified p42(IP4)/centaurin alpha1 and cytohesins-proteins with high affinity for the messengers D-inositol 1,3,4,5-tetrakisphosphate/phosphatidylinositol 3,4,5-trisphosphate. Biochimica Et Biophysica Acta. 1651: 102-15. PMID 14499594 DOI: 10.1016/S1570-9639(03)00241-3  1
2003 Azarashvili T, Krestinina O, Odinokova I, Evtodienko Y, Reiser G. Physiological Ca2+ level and Ca2+-induced Permeability Transition Pore control protein phosphorylation in rat brain mitochondria. Cell Calcium. 34: 253-9. PMID 12887972 DOI: 10.1016/S0143-4160(03)00107-6  1
2003 Strokin M, Sergeeva M, Reiser G. Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+. British Journal of Pharmacology. 139: 1014-22. PMID 12839876 DOI: 10.1038/sj.bjp.0705326  1
2003 Rohatgi T, Sedehizade F, Sabel BA, Reiser G. Protease-activated receptor subtype expression in developing eye and adult retina of the rat after optic nerve crush. Journal of Neuroscience Research. 73: 246-54. PMID 12836167 DOI: 10.1002/jnr.10643  1
2003 Laubinger W, Wang H, Welte T, Reiser G. P2Y receptor specific for diadenosine tetraphosphate in lung: selective inhibition by suramin, PPADS, Ip5I, and not by MRS-2197. European Journal of Pharmacology. 468: 9-14. PMID 12729837 DOI: 10.1016/S0014-2999(03)01624-8  1
2003 Schild L, Huppelsberg J, Kahlert S, Keilhoff G, Reiser G. Brain mitochondria are primed by moderate Ca2+ rise upon hypoxia/reoxygenation for functional breakdown and morphological disintegration. The Journal of Biological Chemistry. 278: 25454-60. PMID 12702720 DOI: 10.1074/jbc.M302743200  1
2003 Aggensteiner M, Reiser G. Expression of the brain-specific membrane adapter protein p42IP4/centaurin alpha, a Ins(1,3,4,5)P4/PtdIns(3,4,5)P3 binding protein, in developing rat brain. Brain Research. Developmental Brain Research. 142: 77-87. PMID 12694946 DOI: 10.1016/S0165-3806(03)00033-6  1
2003 Schafer R, Sedehizade F, Welte T, Reiser G. ATP- and UTP-activated P2Y receptors differently regulate proliferation of human lung epithelial tumor cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L376-85. PMID 12691958 DOI: 10.1152/ajplung.00447.2002  1
2003 Wang H, Reiser G. Thrombin signaling in the brain: the role of protease-activated receptors. Biological Chemistry. 384: 193-202. PMID 12675511 DOI: 10.1515/BC.2003.021  1
2003 Sergeeva M, Strokin M, Wang H, Ubl JJ, Reiser G. Arachidonic acid in astrocytes blocks Ca(2+) oscillations by inhibiting store-operated Ca(2+) entry, and causes delayed Ca(2+) influx. Cell Calcium. 33: 283-92. PMID 12618149 DOI: 10.1016/S0143-4160(03)00011-3  1
2003 Wang H, Reiser G. The role of the Ca2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes. Journal of Neurochemistry. 84: 1349-57. PMID 12614335 DOI: 10.1046/j.1471-4159.2003.01637.x  1
2003 Xi G, Reiser G, Keep RF. The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective? Journal of Neurochemistry. 84: 3-9. PMID 12485396 DOI: 10.1046/j.1471-4159.2003.01268.x  1
2003 Wang H, Reiser G. Signal transduction by serine proteinases in astrocytes: Regulation of proliferation, morphologic changes, and survival via proteinase-activated receptors Drug Development Research. 60: 43-50. DOI: 10.1002/ddr.10319  1
2002 Reiser G, Bernstein HG. Neurons and plaques of Alzheimer's disease patients highly express the neuronal membrane docking protein p42IP4/centaurin alpha. Neuroreport. 13: 2417-9. PMID 12499840 DOI: 10.1097/01.wnr.0000048005.96487.10  1
2002 Nahum V, Zündorf G, Lévesque SA, Beaudoin AR, Reiser G, Fischer B. Adenosine 5'-O-(1-boranotriphosphate) derivatives as novel P2Y(1) receptor agonists. Journal of Medicinal Chemistry. 45: 5384-96. PMID 12431066 DOI: 10.1021/jm020251d  1
2002 Wang H, Ubl JJ, Stricker R, Reiser G. Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways. American Journal of Physiology. Cell Physiology. 283: C1351-64. PMID 12372796 DOI: 10.1152/ajpcell.00001.2002  1
2002 Kahlert S, Reiser G. Swelling of mitochondria in cultured rat hippocampal astrocytes is induced by high cytosolic Ca(2+) load, but not by mitochondrial depolarization. Febs Letters. 529: 351-5. PMID 12372627 DOI: 10.1016/S0014-5793(02)03394-X  1
2002 Sergeeva M, Strokin M, Wang H, Ubl JJ, Reiser G. Arachidonic acid and docosahexaenoic acid suppress thrombin-evoked Ca2+ response in rat astrocytes by endogenous arachidonic acid liberation. Journal of Neurochemistry. 82: 1252-61. PMID 12358772 DOI: 10.1046/j.1471-4159.2002.01052.x  1
2002 Riek-Burchardt M, Striggow F, Henrich-Noack P, Reiser G, Reymann KG. Increase of prothrombin-mRNA after global cerebral ischemia in rats, with constant expression of protease nexin-1 and protease-activated receptors. Neuroscience Letters. 329: 181-4. PMID 12165407 DOI: 10.1016/S0304-3940(02)00645-6  1
2002 Ubl JJ, Grishina ZV, Sukhomlin TK, Welte T, Sedehizade F, Reiser G. Human bronchial epithelial cells express PAR-2 with different sensitivity to thermolysin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1339-48. PMID 12003791 DOI: 10.1152/ajplung.00392.2001  1
2002 Sedehizade F, Hanck T, Stricker R, Horstmayer A, Bernstein HG, Reiser G. Cellular expression and subcellular localization of the human Ins(1,3,4,5)P(4)-binding protein, p42(IP4), in human brain and in neuronal cells. Brain Research. Molecular Brain Research. 99: 1-11. PMID 11869802 DOI: 10.1016/S0169-328X(01)00335-7  1
2002 Wang H, Ubl JJ, Reiser G. Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling. Glia. 37: 53-63. PMID 11746783 DOI: 10.1002/glia.10012  1
2001 Kahlert S, Schild L, Reiser G. Mitochondrial polarization in rat hippocampal astrocytes is resistant to cytosolic Ca(2+) loads. Journal of Neuroscience Research. 66: 1019-27. PMID 11746432 DOI: 10.1002/jnr.10052  1
2001 Striggow F, Riek-Burchardt M, Kiesel A, Schmidt W, Henrich-Noack P, Breder J, Krug M, Reymann KG, Reiser G. Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia. The European Journal of Neuroscience. 14: 595-608. PMID 11556885 DOI: 10.1046/j.0953-816X.2001.01676.x  1
2001 Zündorf G, Schäfer R, Vöhringer C, Halbfinger E, Fischer B, Reiser G. Novel modified adenosine 5'-triphosphate analogues pharmacologically characterized in human embryonic kidney 293 cells highly expressing rat brain P2Y(1) receptor: Biotinylated analogue potentially suitable for specific P2Y(1) receptor isolation. Biochemical Pharmacology. 61: 1259-69. PMID 11322930 DOI: 10.1016/S0006-2952(01)00593-7  1
2001 Schild L, Keilhoff G, Augustin W, Reiser G, Striggow F. Distinct Ca2+ thresholds determine cytochrome c release or permeability transition pore opening in brain mitochondria. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 565-7. PMID 11259368 DOI: 10.1096/fj.00-0551fje  1
2001 Laubinger W, Streubel G, Reiser G. Physiological evidence for a P2Y receptor responsive to diadenosine polyphosphates in human lung via Ca(2+) release studies in bronchial epithelial cells. Biochemical Pharmacology. 61: 623-9. PMID 11239506 DOI: 10.1016/S0006-2952(00)00590-6  1
2001 Vöhringer C, Reiser G. Pharmacological characterization of the rat brain P2Y1 receptor expressed in HEK293 cells: Ca2+ signaling and receptor regulation Drug Development Research. 53: 172-179. DOI: 10.1002/ddr.1185  1
2000 Kahlert S, Reiser G. Requirement of glycolytic and mitochondrial energy supply for loading of Ca(2+) stores and InsP(3)-mediated Ca(2+) signaling in rat hippocampus astrocytes. Journal of Neuroscience Research. 61: 409-20. PMID 10931527 DOI: 10.1002/1097-4547(20000815)61:4<409::AID-JNR7>3.0.CO;2-M  1
2000 Ubl JJ, Reiser G. A novel proteolytic mechanism for termination of the CA2+ signalling evoked by proteinase-activated receptor-1 (PAR-1) in rat astrocytes. Advances in Experimental Medicine and Biology. 477: 323-9. PMID 10849760 DOI: 10.1007/0-306-46826-3_35  1
2000 Sergeeva M, Ubl JJ, Reiser G. Disruption of actin cytoskeleton in cultured rat astrocytes suppresses ATP- and bradykinin-induced [Ca(2+)](i) oscillations by reducing the coupling efficiency between Ca(2+) release, capacitative Ca(2+) entry, and store refilling. Neuroscience. 97: 765-9. PMID 10842022 DOI: 10.1016/S0306-4522(00)00062-2  1
2000 Ubl JJ, Sergeeva M, Reiser G. Desensitisation of protease-activated receptor-1 (PAR-1) in rat astrocytes: evidence for a novel mechanism for terminating Ca2+ signalling evoked by the tethered ligand. The Journal of Physiology. 525: 319-30. PMID 10835036  1
2000 Vöhringer C, Schäfer R, Reiser G. A chimeric rat brain P2Y1 receptor tagged with green-fluorescent protein: high-affinity ligand recognition of adenosine diphosphates and triphosphates and selectivity identical to that of the wild-type receptor. Biochemical Pharmacology. 59: 791-800. PMID 10718337 DOI: 10.1016/S0006-2952(99)00390-1  1
2000 Striggow F, Riek M, Breder J, Henrich-Noack P, Reymann KG, Reiser G. The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proceedings of the National Academy of Sciences of the United States of America. 97: 2264-9. PMID 10681455 DOI: 10.1073/pnas.040552897  1
1999 Halbfinger E, Major DT, Ritzmann M, Ubl J, Reiser G, Boyer JL, Harden KT, Fischer B. Molecular recognition of modified adenine nucleotides by the P2Y(1)-receptor. 1. A synthetic, biochemical, and NMR approach. Journal of Medicinal Chemistry. 42: 5325-37. PMID 10639276 DOI: 10.1021/jm990156d  1
1999 Reiser G, Laubinger W, Schäfer R. Nucleotide radiolabels as tools for studying P2Y receptors in membranes from brain and lung tissue. Progress in Brain Research. 120: 45-58. PMID 10550987  1
1999 Laubinger W, Welte T, Streubel G, Schäfer HJ, Reiser G. In human and rat lung membranes [35S]GTPgammaS binding is a tool for pharmacological characterization of G protein-coupled dinucleotide receptors. Life Sciences. 65: PL183-90. PMID 10530805 DOI: 10.1016/S0024-3205(99)00394-X  1
1999 Stricker R, Adelt S, Vogel G, Reiser G. Translocation between membranes and cytosol of p42IP4, a specific inositol 1,3,4,5-tetrakisphosphate/phosphatidylinositol 3,4, 5-trisphosphate-receptor protein from brain, is induced by inositol 1,3,4,5-tetrakisphosphate and regulated by a membrane-associated 5-phosphatase. European Journal of Biochemistry / Febs. 265: 815-24. PMID 10504414 DOI: 10.1046/j.1432-1327.1999.00795.x  1
1997 Kreutz MR, Böckers TM, Sabel BA, Hülser E, Stricker R, Reiser G. Expression and subcellular localization of p42IP4/centaurin-alpha, a brain-specific, high-affinity receptor for inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate in rat brain. The European Journal of Neuroscience. 9: 2110-24. PMID 9421171 DOI: 10.1111/j.1460-9568.1997.tb01378.x  1
1997 Kreutz MR, Böckers TM, Sabel BA, Stricker R, Hülser E, Reiser G. Localization of a 42-kDa inositol 1,3,4,5-tetrakisphosphate receptor protein in retina and change in expression after optic nerve injury. Brain Research. Molecular Brain Research. 45: 283-93. PMID 9149103 DOI: 10.1016/S0169-328X(96)00264-1  1
1996 Czubayko U, Reiser G. Desensitization of P2U receptor in neuronal cell line. Different control by the agonists ATP and UTP, as demonstrated by single-cell Ca2+ responses. The Biochemical Journal. 320: 215-9. PMID 8947490  1
1996 Czubayko U, Reiser G. P2U nucleotide receptor activation in rat glial cell line induces [Ca2+]i oscillations which depend on cytosolic pH. Glia. 16: 108-16. PMID 8929898 DOI: 10.1002/(SICI)1098-1136(199602)16:2<108::AID-GLIA3>3.0.CO;2-#  1
1995 Czubayko U, Reiser G. [Ca2+]i oscillations in single rat glioma cells induced by thrombin through activation of cell surface receptors. Neuroreport. 6: 1249-52. PMID 7669979  1
1991 Lohmann F, Drews U, Donié F, Reiser G. Chick embryo muscarinic and purinergic receptors activate cytosolic Ca2+ via phosphatidylinositol metabolism. Experimental Cell Research. 197: 326-9. PMID 1959565 DOI: 10.1016/0014-4827(91)90441-V  1
1990 Reiser G, Binmöller FJ, Strong PN, Hamprecht B. Activation of a K+ conductance by bradykinin and by inositol-1,4,5-trisphosphate in rat glioma cells: involvement of intracellular and extracellular Ca2+. Brain Research. 506: 205-14. PMID 2302562 DOI: 10.1016/0006-8993(90)91252-C  1
1989 Reiser G, Uchitel O, Miledi R. Neuronal control of extrajunctional acetylcholine receptor-channels induced by injury in frog skeletal muscle fibres. PflüGers Archiv : European Journal of Physiology. 414: 113-7. PMID 2787904 DOI: 10.1007/BF00580951  1
1989 Reiser G, Hamprecht B. Serotonin raises the cyclic GMP level in a neuronal cell line via 5-HT3 receptors. European Journal of Pharmacology. 172: 195-8. PMID 2548882 DOI: 10.1016/0922-4106(89)90010-2  1
1989 Reiser G, Miledi R. Changes in the properties of synaptic channels opened by acetylcholine in denervated frog muscle. Brain Research. 479: 83-97. PMID 2466537 DOI: 10.1016/0006-8993(89)91338-3  1
1989 Reiser G, Hamprecht B. Substance P and serotonin act synergistically to activate a cation permeability in a neuronal cell line. Brain Research. 479: 40-8. PMID 2466536 DOI: 10.1016/0006-8993(89)91333-4  1
1988 Reiser G, Miledi R. Characteristics of Schwann-cell miniature end-plate currents in denervated frog muscle. PflüGers Archiv : European Journal of Physiology. 412: 22-8. PMID 2459657 DOI: 10.1007/BF00583727  1
1988 Reiser G, Hamprecht B. Characterization of a substance P receptor activating a cation permeability in neuronal cell lines. European Journal of Pharmacology. 145: 273-80. PMID 2450763 DOI: 10.1016/0014-2999(88)90430-X  1
1987 Höpp HP, Reuter G, Reiser G, Hamprecht B. Angiotensin evokes in polyploid rat glioma cells hyperpolarization-depolarization responses and cross-desensitization with bradykinin. Brain Research. 412: 175-8. PMID 3607452 DOI: 10.1016/0006-8993(87)91456-9  1
1987 Reiser G, Binmöller FJ, Hamprecht B. The regulatory influence of bradykinin and inositol-1,4,5-trisphosphate on the membrane potential in neural cell lines. Biomedica Biochimica Acta. 46: S682-7. PMID 2449200  1
1987 Reiser G, Höpp HP, Hamprecht B. Atrial natriuretic polypeptide hormones induce membrane potential responses in cultured rat glioma cells. Brain Research. 402: 164-7. PMID 2435362 DOI: 10.1016/0006-8993(87)91061-4  1
1985 Reiser G, Hamprecht B. Bradykinin causes a transient rise of intracellular Ca2+-activity in cultured neural cells. PflüGers Archiv : European Journal of Physiology. 405: 260-4. PMID 4069982 DOI: 10.1007/BF00582570  1
1985 Reiser G, Hamprecht B. The influence of bradykinin on intracellular Ca++-activity in cultured neural cells. Regulatory Peptides. Supplement. 4: 46-8. PMID 3864199  1
1985 Hamprecht B, Glaser T, Reiser G, Bayer E, Propst F. Culture and characteristics of hormone-responsive neuroblastoma X glioma hybrid cells. Methods in Enzymology. 109: 316-41. PMID 2985920 DOI: 10.1016/0076-6879(85)09096-6  1
1985 Reiser G, Höpp HP, Hamprecht B. The effect of atriopeptin III on membrane potential and intracellular Ca++-activity in rat glioma cells. Regulatory Peptides. Supplement. 4: 101-3. PMID 2932772  1
1984 Reiser G, Walter U, Hamprecht B. Bradykinin regulates the level of guanosine 3',5'-cyclic monophosphate (cyclic GMP) in neural cell lines. Brain Research. 290: 367-71. PMID 6318912 DOI: 10.1016/0006-8993(84)90958-2  1
1984 Miledi R, Reiser G, Uchitel OD. Characteristics of membrane channels induced by acetylcholine at frog muscle-tendon junctions. The Journal of Physiology. 350: 269-77. PMID 6086895 DOI: 10.1113/jphysiol.1984.sp015200  1
1983 Reiser G, Hamprecht B. Sodium-channels in non-excitable glioma cells, shown by the influence of veratridine, scorpion toxin, and tetrodotoxin on membrane potential and on ion transport. PflüGers Archiv : European Journal of Physiology. 397: 260-4. PMID 6310481 DOI: 10.1007/BF00580258  1
1983 Reiser G, Löffler F, Hamprecht B. Tetrodotoxin-sensitive ion channels characterized in glial and neuronal cells from rat brain. Brain Research. 261: 335-40. PMID 6299468 DOI: 10.1016/0006-8993(83)90640-6  1
1983 Reiser G, Günther A, Hamprecht B. Blockade by neurotransmitter antagonists of veratridine-activated ion channels in neuronal cell lines. Journal of Neurochemistry. 40: 493-502. PMID 6130127  1
1982 Reiser G, Hamprecht B. Bradykinin induces hyperpolarizations in rat glioma cells and in neuroblastoma X glioma hybrid cells. Brain Research. 239: 191-9. PMID 7093675 DOI: 10.1016/0006-8993(82)90841-1  1
1982 Reiser G, Hamprecht B. Differential effects of various cAMP derivatives on the morphological and electrical maturation of neuroblastoma x glioma hybrid cells. Experimental Cell Research. 141: 498-503. PMID 6291962 DOI: 10.1016/0014-4827(82)90243-9  1
1982 Reiser G, Günther A, Hamprecht B. Strychnine and local anesthetics block ion channels activated by veratridine in neuroblastoma x glioma hybrid cells. Febs Letters. 143: 306-10. PMID 6288467 DOI: 10.1016/0014-5793(82)80122-1  1
1982 Reiser G, Scholz F, Hamprecht B. Pharmacological and electrophysiological characterization of lithium ion flux through the action potential sodium channel in neuroblastoma X glioma hybrid cells. Journal of Neurochemistry. 39: 228-34. PMID 6283018  1
1982 Reiser G, Folkers K, Hamprecht B. Substance P enhances cation permeability of neuronal cell lines. Regulatory Peptides. 5: 85-93. PMID 6188189 DOI: 10.1016/0167-0115(82)90078-7  1
1982 Heumann R, Reiser G, Van Calker D, Hamprecht B. Polyploid rat glioma cells. Production, oscillations of membrane potential and response to neurohormones. Experimental Cell Research. 139: 117-26. PMID 6123437 DOI: 10.1016/0014-4827(82)90325-1  1
1977 Reiser G, Heumann R, Kemper W, Lautenschlager E, Hamprecht B. Influence of cations on the electrical activity of neuroblastoma X glioma hybrid cells. Brain Research. 130: 495-504. PMID 890447 DOI: 10.1016/0014-5793(77)80269-X  1
1977 Heumann R, Stavrou D, Reiser G, Ocalan M, Hamprecht B. Tumorigenicity of neuroblastoma X glioma hybrid cells in nude mice and reintroduction of transplanted cells into culture. European Journal of Cancer. 13: 1417-20. PMID 598387 DOI: 10.1016/0014-2964(77)90155-4  1
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