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Alan Finkelstein, Ph.D. - Related publications

Affiliations: 
Physiology & Biophysics, and Neuroscience Albert Einstein College of Medicine, New York, New York, United States 
Area:
Ion-Conducting Channels Incorporated into Planar Lipid Bilayer Membranes
Website:
http://galvani.aecom.yu.edu/home.html
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Schlegel AM, Haswell ES. Analyzing plant mechanosensitive ion channels expressed in giant E. coli spheroplasts by single-channel patch-clamp electrophysiology. Methods in Cell Biology. 160: 61-82. PMID 32896333 DOI: 10.1016/bs.mcb.2020.02.007   
2020 Zheng SP, Jiang JJ, van der Lee A, Barboiu M. Voltage-responsive synthetic Cl--channel regulated by pH. Angewandte Chemie (International Ed. in English). PMID 32820831 DOI: 10.1002/anie.202008393   
2020 Schaub C, Verdi J, Lee P, Terra N, Limon G, Raper J, Thomson R. Cation channel conductance and pH gating of the innate immunity factor APOL1 is governed by pore lining residues within the C-terminal domain. The Journal of Biological Chemistry. PMID 32727852 DOI: 10.1074/jbc.RA120.014201   
2020 Mony L, Stroebel D, Isacoff EY. Dimer interaction in the Hv1 proton channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 32788354 DOI: 10.1073/pnas.2010032117   
2020 Huffer KE, Aleksandrova AA, Jara-Oseguera A, Forrest LR, Swartz KJ. Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms. Elife. 9. PMID 32804077 DOI: 10.7554/eLife.58660   
2020 Guan W, Stephens RF, Mourad O, Mehta A, Fux J, Spafford JD. Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca3 T-type channels alter the passage and block of monovalent and divalent ions. Scientific Reports. 10: 12404. PMID 32710088 DOI: 10.1038/s41598-020-69197-3   
2020 Kim DH, Park WH, Oh HG, Jeon DC, Lim JM, Song KS. Two-Channel Graphene pH Sensor Using Semi-Ionic Fluorinated Graphene Reference Electrode. Sensors (Basel, Switzerland). 20. PMID 32731474 DOI: 10.3390/s20154184   
2020 Codding SJ, Johnson AA, Trudeau MC. Gating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains. Channels (Austin, Tex.). 14: 294-309. PMID 32924766 DOI: 10.1080/19336950.2020.1816107   
2020 Bakowski D, Murray F, Parekh AB. Store-Operated Ca Channels: Mechanism, Function, Pharmacology, and Therapeutic Targets. Annual Review of Pharmacology and Toxicology. PMID 32966177 DOI: 10.1146/annurev-pharmtox-031620-105135   
2020 Díaz-Franulic I, Raddatz N, Castillo K, González-Nilo FD, Latorre R. A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747539 DOI: 10.1073/pnas.2004303117   
2020 Han Y, Li T, Wang S, Chen J. A Flow-Measuring Algorithm of Arc-Bottomed Open Channels through Multiple Characteristic Sensing Points of the Flow-Velocity Sensor in Agricultural Irrigation Areas. Sensors (Basel, Switzerland). 20. PMID 32806577 DOI: 10.3390/s20164504   
2020 Cherny VV, Musset B, Morgan D, Thomas S, Smith SME, DeCoursey TE. Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel. The Journal of General Physiology. 152. PMID 32902579 DOI: 10.1085/jgp.202012664   
2020 Niu Y, Tao X, Touhara KK, MacKinnon R. Cryo-EM analysis of PIP regulation in mammalian GIRK channels. Elife. 9. PMID 32844743 DOI: 10.7554/eLife.60552   
2020 Leong IW, Tsutsui M, Murayama S, He Y, Taniguchi M. Electroosmosis-Driven Nanofluidic Diodes. The Journal of Physical Chemistry. B. PMID 32701281 DOI: 10.1021/acs.jpcb.0c04677   
2020 Dreyer I, Sussmilch FC, Fukushima K, Riadi G, Becker D, Schultz J, Hedrich R. How to Grow a Tree: Plant Voltage-Dependent Cation Channels in the Spotlight of Evolution. Trends in Plant Science. PMID 32868178 DOI: 10.1016/j.tplants.2020.07.011   
2020 Morán-Zendejas R, Delgado-Ramírez M, Xu J, Valdés-Abadía B, Aréchiga-Figueroa IA, Cui M, Rodríguez-Menchaca AA. In vitro and in silico characterization of the inhibition of Kir4.1 channels by aminoglycoside antibiotics. British Journal of Pharmacology. PMID 32726456 DOI: 10.1111/bph.15214   
2020 Diniz AFA, Ferreira RC, de Souza ILL, da Silva BA. Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review. Frontiers in Pharmacology. 11: 1120. PMID 32848741 DOI: 10.3389/fphar.2020.01120   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Xie Z, Zhao Y, Yang W, Li W, Wu Y, Chen Z. Methotrexate, a small molecular scaffold targeting Kv1.3 channel extracellular pore region. Biochemical and Biophysical Research Communications. PMID 32863001 DOI: 10.1016/j.bbrc.2020.08.050   
2020 Burton MJ, Cresser-Brown J, Thomas M, Portolano N, Basran J, Freeman SL, Kwon H, Bottrill AR, Llansola-Portoles MJ, Pascal AA, Jukes-Jones R, Chernova T, Schmid R, Davies NW, Storey NM, et al. Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel. The Journal of Biological Chemistry. PMID 32723862 DOI: 10.1074/jbc.RA120.014150   
2020 Hong L, Zhang M, Sridhar A, Darbar D. Pathogenic mutations perturb calmodulin regulation of Na1.8 channel. Biochemical and Biophysical Research Communications. PMID 32948286 DOI: 10.1016/j.bbrc.2020.08.010   
2020 Chen LC, Zheng J, Liu J, Gong XT, Chen ZZ, Guo RX, Huang X, Zhang YP, Zhang L, Li R, Shao X, Hong W, Zhang HL. Nonadditive Transport in Multi-Channel Single-Molecule Circuits. Small (Weinheim An Der Bergstrasse, Germany). e2002808. PMID 32851802 DOI: 10.1002/smll.202002808   
2020 López-Vera E, Martínez-Hernández L, Aguilar MB, Carrillo E, Gajewiak J. Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes. Marine Drugs. 18. PMID 32823677 DOI: 10.3390/md18080425   
2020 Mondéjar-Parreño G, Barreira B, Callejo M, Morales-Cano D, Barrese V, Esquivel-Ruiz S, Olivencia MA, Macías M, Moreno L, Greenwood IA, Perez-Vizcaino F, Cogolludo A. Uncovered Contribution of Kv7 Channels to Pulmonary Vascular Tone in Pulmonary Arterial Hypertension. Hypertension (Dallas, Tex. : 1979). 76: 1134-1146. PMID 32829658 DOI: 10.1161/HYPERTENSIONAHA.120.15221   
2020 Kolen B, Kortzak D, Franzen A, Fahlke C. An amino-terminal point mutation increases EAAT2 anion currents without affecting glutamate transport rates. The Journal of Biological Chemistry. PMID 32820048 DOI: 10.1074/jbc.RA120.013704   
2020 Langan PS, Vandavasi VG, Kopec W, Sullivan B, Afonne PV, Weiss KL, de Groot BL, Coates L. The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation. Iucrj. 7: 835-843. PMID 32939275 DOI: 10.1107/S2052252520008271   
2020 Capatina AL, Lagos D, Brackenbury WJ. Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges. Reviews of Physiology, Biochemistry and Pharmacology. PMID 32865696 DOI: 10.1007/112_2020_46   
2020 Kim JH, Won J, Oh SB. Expression of Ca3.1 T-type Calcium Channels in Acutely Isolated Adult Rat Odontoblasts. Archives of Oral Biology. 118: 104864. PMID 32847753 DOI: 10.1016/j.archoralbio.2020.104864   
2020 Cardoso FC, Marliac MA, Geoffroy C, Schmit M, Bispat A, Lewis RJ, Tuck KL, Duggan PJ. The neuronal calcium ion channel activity of constrained analogues of MONIRO-1. Bioorganic & Medicinal Chemistry. 28: 115655. PMID 32828422 DOI: 10.1016/j.bmc.2020.115655   
2020 Kim JM, Song KS, Xu B, Wang T. Role of potassium channels in female reproductive system. Obstetrics & Gynecology Science. PMID 32838485 DOI: 10.5468/ogs.20064   
2020 Boente-Juncal A, Raposo-Garcia S, Costas C, Louzao MC, Vale C, Botana LM. Partial blockade of human voltage-dependent sodium channels by the marine toxins azaspiracids. Chemical Research in Toxicology. PMID 32872774 DOI: 10.1021/acs.chemrestox.0c00216   
2020 Zhang Q, Si Y, Yang L, Wang L, Peng S, Chen Y, Chen M, Zhou X, Liu Z. Two Novel Peptide Toxins from the Spider Inhibit Tetrodotoxin-Sensitive Sodium Channels. Toxins. 12. PMID 32824960 DOI: 10.3390/toxins12090529   
2020 Milenkovic S, Bodrenko IV, Lagostena L, Gradogna A, Serra G, Bosin A, Carpaneto A, Ceccarelli M. The mechanism and energetics of a ligand-controlled hydrophobic gate in a mammalian two pore channel. Physical Chemistry Chemical Physics : Pccp. 22: 15664-15674. PMID 32618303 DOI: 10.1039/d0cp00805b   
2020 Ma Y, Luo Q, Fu J, Che Y, Guo F, Mei L, Zhang Q, Li Y, Yang H. Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating. Journal of Medicinal Chemistry. PMID 32877186 DOI: 10.1021/acs.jmedchem.0c00842   
2020 Cottone G, Chiodo L, Maragliano L. Thermodynamics and Kinetics of Ion Permeation in Wild-Type and Mutated Open Active Conformation of the Human α7 Nicotinic Receptor. Journal of Chemical Information and Modeling. PMID 32803965 DOI: 10.1021/acs.jcim.0c00549   
2020 Ren Y, Wen T, Xi Z, Li S, Lu J, Zhang X, Yang X, Shen Y. Cryo-EM structure of the calcium homeostasis modulator 1 channel. Science Advances. 6: eaba8161. PMID 32832630 DOI: 10.1126/sciadv.aba8161   
2020 Brauchi SE, Rothberg BS. Gating and calcium-sensing mechanisms of TRPA1 channels revealed. Cell Calcium. 91: 102278. PMID 32858446 DOI: 10.1016/j.ceca.2020.102278   
2020 Pantazis A, Kaneko M, Angelini M, Steccanella F, Westerlund AM, Lindström SH, Nilsson M, Delemotte L, Saitta SC, Olcese R. Tracking the motion of K 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy. The Journal of Physiology. PMID 32833227 DOI: 10.1113/JP280438   
2020 Hajian G, Etemad A, Morin E. Automated Channel Selection in High-Density sEMG for Improved Force Estimation. Sensors (Basel, Switzerland). 20. PMID 32867378 DOI: 10.3390/s20174858   
2020 Kumar A, Basak S, Rao S, Gicheru Y, Mayer ML, Sansom MSP, Chakrapani S. Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nature Communications. 11: 3752. PMID 32719334 DOI: 10.1038/s41467-020-17364-5   
2020 Himmel NJ, Cox DN. Transient receptor potential channels: current perspectives on evolution, structure, function and nomenclature. Proceedings. Biological Sciences. 287: 20201309. PMID 32842926 DOI: 10.1098/rspb.2020.1309   
2020 Timic Stamenic T, Feseha S, Manzella FM, Wallace D, Wilkey D, Corrigan T, Fiedler H, Doerr P, Krishnan K, Raol YH, Covey DF, Jevtovic-Todorovic V, Todorovic SM. The T-type calcium channel isoform Ca3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile. British Journal of Anaesthesia. PMID 32859366 DOI: 10.1016/j.bja.2020.07.022   
2020 Rose P, Schleimer JH, Schreiber S. Modifications of sodium channel voltage dependence induce arrhythmia-favouring dynamics of cardiac action potentials. Plos One. 15: e0236949. PMID 32750067 DOI: 10.1371/journal.pone.0236949   
2020 Wu F, Sun H, Gong W, Li X, Pan Z, Shan H, Zhang Z. Genetic and pharmacological inhibition of two-pore domain potassium channel TREK-1 alters depression-related behaviors and neuronal plasticity in the hippocampus in mice. Cns Neuroscience & Therapeutics. PMID 32864894 DOI: 10.1111/cns.13450   
2020 Majhi RK, Kumar A, Giri SC, Goswami C. Differential expression and localization of TRPV channels in the mature sperm of Anas platyrhynchos. Reproduction in Domestic Animals = Zuchthygiene. PMID 32920930 DOI: 10.1111/rda.13822   
2020 Lee HJ, Jeong H, Hyun J, Ryu B, Park K, Lim HH, Yoo J, Woo JS. Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Science Advances. 6: eaba4996. PMID 32923625 DOI: 10.1126/sciadv.aba4996   
2020 Cooper G, Kang S, Perez-Rosello T, Guzman JN, Galtieri D, Xie Z, Kondapalli J, Mordell J, Silverman RB, Surmeier DJ. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca1.3 L-Type Calcium Channels. Acs Chemical Biology. PMID 32881483 DOI: 10.1021/acschembio.0c00577   
2020 Wang R, Tu S, Zhang J, Shao A. Roles of TRP Channels in Neurological Diseases. Oxidative Medicine and Cellular Longevity. 2020: 7289194. PMID 32963700 DOI: 10.1155/2020/7289194