| Year |
Citation |
Score |
| 2019 |
Sosa Y, Deniskin R, Frame IJ, Steiginga MS, Bandyopadhyay D, Graybill TL, Kallal LA, Ouellette MT, Pope AJ, Widdowson KL, Young RJ, Akabas MH. Parallel Hit Progression Strategy Identifies Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Parasite Proliferation. Acs Infectious Diseases. PMID 31373203 DOI: 10.1021/Acsinfecdis.9B00168 |
0.321 |
|
| 2018 |
Nishtala SN, Arora A, Reyes J, Akabas MH. Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the equilibrative nucleoside transporter PfENT1. The Journal of Biological Chemistry. PMID 30541922 DOI: 10.1074/jbc.RA118.006547 |
0.401 |
|
| 2016 |
Arora A, Deniskin R, Sosa Y, Nishtala SN, Henrich PP, Kumar TR, Fidock DA, Akabas MH. Substrate and inhibitor specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1 (PbENT1). Molecular Pharmacology. PMID 27048953 DOI: 10.1124/Mol.115.101386 |
0.363 |
|
| 2016 |
Deniskin R, Frame IJ, Sosa Y, Akabas MH. Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development. International Journal For Parasitology. Drugs and Drug Resistance. 6: 1-11. PMID 26862473 DOI: 10.1016/j.ijpddr.2015.11.003 |
0.767 |
|
| 2015 |
Akabas MH. Cysteine Modification: Probing Channel Structure, Function and Conformational Change. Advances in Experimental Medicine and Biology. 869: 25-54. PMID 26381939 DOI: 10.1007/978-1-4939-2845-3_3 |
0.405 |
|
| 2015 |
Frame IJ, Deniskin R, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH. Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites. Acs Chemical Biology. 10: 775-83. PMID 25602169 DOI: 10.1021/Cb500981Y |
0.77 |
|
| 2015 |
Frame IJ, Deniskin R, Arora A, Akabas MH. Purine import into malaria parasites as a target for antimalarial drug development. Annals of the New York Academy of Sciences. 1342: 19-28. PMID 25424653 DOI: 10.1111/nyas.12568 |
0.76 |
|
| 2013 |
Akabas MH. Using molecular dynamics to elucidate the structural basis for function in pLGICs. Proceedings of the National Academy of Sciences of the United States of America. 110: 16700-1. PMID 24096580 DOI: 10.1073/pnas.1316157110 |
0.371 |
|
| 2013 |
Brunner R, Ng CL, Aissaoui H, Akabas MH, Boss C, Brun R, Callaghan PS, Corminboeuf O, Fidock DA, Frame IJ, Heidmann B, Le Bihan A, Jenö P, Mattheis C, Moes S, et al. UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells. The Journal of Biological Chemistry. 288: 22576-83. PMID 23754276 DOI: 10.1074/Jbc.M113.453159 |
0.753 |
|
| 2012 |
Akabas MH. Channels: Rotamers affect ion conductance. Nature Chemical Biology. 8: 953-4. PMID 23183578 DOI: 10.1038/nchembio.1115 |
0.433 |
|
| 2012 |
Bali M, Akabas MH. Gating-induced conformational rearrangement of the γ-aminobutyric acid type A receptor β-α subunit interface in the membrane-spanning domain. The Journal of Biological Chemistry. 287: 27762-70. PMID 22730325 DOI: 10.1074/Jbc.M112.363341 |
0.64 |
|
| 2012 |
Frame IJ, Merino EF, Schramm VL, Cassera MB, Akabas MH. Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity. The Biochemical Journal. 446: 179-90. PMID 22670848 DOI: 10.1042/Bj20112220 |
0.776 |
|
| 2012 |
Collins B, Kane EA, Reeves DC, Akabas MH, Blau J. Balance of activity between LN(v)s and glutamatergic dorsal clock neurons promotes robust circadian rhythms in Drosophila. Neuron. 74: 706-18. PMID 22632728 DOI: 10.1016/J.Neuron.2012.02.034 |
0.662 |
|
| 2012 |
McKinnon NK, Bali M, Akabas MH. Length and amino acid sequence of peptides substituted for the 5-HT3A receptor M3M4 loop may affect channel expression and desensitization. Plos One. 7: e35563. PMID 22539982 DOI: 10.1371/Journal.Pone.0035563 |
0.804 |
|
| 2012 |
Collins B, Kane EA, Reeves DC, Akabas MH, Blau J. Balance of Activity between LN vs and Glutamatergic Dorsal Clock Neurons Promotes Robust Circadian Rhythms in Drosophila Neuron. 74: 1138. DOI: 10.1016/j.neuron.2012.06.007 |
0.633 |
|
| 2011 |
Akabas MH. Ion channels: Manipulating the munchies in mice. Nature Chemical Biology. 7: 759-60. PMID 22008994 DOI: 10.1038/nchembio.697 |
0.338 |
|
| 2011 |
McKinnon NK, Reeves DC, Akabas MH. 5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals. The Journal of General Physiology. 138: 453-66. PMID 21948949 DOI: 10.1085/Jgp.201110686 |
0.789 |
|
| 2011 |
Ekland EH, Akabas MH, Fidock DA. Taking Charge: Feeding Malaria via Anion Channels. Cell. 145: 645-7. PMID 21620131 DOI: 10.1016/J.Cell.2011.05.012 |
0.363 |
|
| 2011 |
Parikh RB, Bali M, Akabas MH. Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility. The Journal of Biological Chemistry. 286: 14098-109. PMID 21362624 DOI: 10.1074/Jbc.M111.221895 |
0.641 |
|
| 2011 |
Bali M, Akabas MH. Rigid Motion Near the GABAA Receptor α1 Subunit First Transmembrane Segment Revealed by pCMBS- Reactivity in Cysteine-Substituted Mutants During Channel Activation Biophysical Journal. 100: 275a. DOI: 10.1016/J.Bpj.2010.12.1712 |
0.629 |
|
| 2010 |
Dahdal D, Reeves DC, Ruben M, Akabas MH, Blau J. Drosophila pacemaker neurons require g protein signaling and GABAergic inputs to generate twenty-four hour behavioral rhythms. Neuron. 68: 964-77. PMID 21145008 DOI: 10.1016/J.Neuron.2010.11.017 |
0.683 |
|
| 2010 |
Riegelhaupt PM, Frame IJ, Akabas MH. Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1). The Journal of Biological Chemistry. 285: 17001-10. PMID 20335165 DOI: 10.1074/Jbc.M110.115758 |
0.777 |
|
| 2010 |
Riegelhaupt PM, Cassera MB, Fröhlich RF, Hazleton KZ, Hefter JJ, Schramm VL, Akabas MH. Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1. Molecular and Biochemical Parasitology. 169: 40-9. PMID 19818813 DOI: 10.1016/J.Molbiopara.2009.10.001 |
0.78 |
|
| 2010 |
Parikh RB, Bali M, Akabas MH. M2 Segment Accessibility in The Prokaryotic Proton-Gated Cys-loop Receptor Channel from Gloeobacter Violaceus in Closed and Open States Biophysical Journal. 98: 130a. DOI: 10.1016/J.Bpj.2009.12.704 |
0.627 |
|
| 2010 |
McKinnon N, Bali M, Akabas MH. Length and Composition of the 5HT3A Receptor M3M4 Loop Effects Channel Expression and Desensitization Biophysical Journal. 98: 129a. DOI: 10.1016/J.Bpj.2009.12.698 |
0.795 |
|
| 2009 |
Nkrumah LJ, Riegelhaupt PM, Moura P, Johnson DJ, Patel J, Hayton K, Ferdig MT, Wellems TE, Akabas MH, Fidock DA. Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE. Molecular and Biochemical Parasitology. 165: 122-31. PMID 19428659 DOI: 10.1016/J.Molbiopara.2009.01.011 |
0.757 |
|
| 2009 |
Bali M, Jansen M, Akabas MH. GABA-induced intersubunit conformational movement in the GABAA receptor alpha 1M1-beta 2M3 transmembrane subunit interface: experimental basis for homology modeling of an intravenous anesthetic binding site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3083-92. PMID 19279245 DOI: 10.1523/Jneurosci.6090-08.2009 |
0.688 |
|
| 2009 |
Parikh R, Bali M, Akabas MH. Identification Of Channel-lining Residues In The Prokaryotic Proton-gated Cys-loop Receptor Ion Channel From Gloeobacter Violaceus Biophysical Journal. 96: 169a. DOI: 10.1016/J.Bpj.2008.12.780 |
0.649 |
|
| 2008 |
Cassera MB, Hazleton KZ, Riegelhaupt PM, Merino EF, Luo M, Akabas MH, Schramm VL. Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum. The Journal of Biological Chemistry. 283: 32889-99. PMID 18799466 DOI: 10.1074/Jbc.M804497200 |
0.769 |
|
| 2008 |
Jansen M, Rabe H, Strehle A, Dieler S, Debus F, Dannhardt G, Akabas MH, Lüddens H. Synthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding site. Journal of Medicinal Chemistry. 51: 4430-48. PMID 18651727 DOI: 10.1021/Jm701562X |
0.503 |
|
| 2008 |
Zhao R, Qiu A, Tsai E, Jansen M, Akabas MH, Goldman ID. The proton-coupled folate transporter: impact on pemetrexed transport and on antifolates activities compared with the reduced folate carrier. Molecular Pharmacology. 74: 854-62. PMID 18524888 DOI: 10.1124/Mol.108.045443 |
0.518 |
|
| 2008 |
Jansen M, Bali M, Akabas MH. Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop. The Journal of General Physiology. 131: 137-46. PMID 18227272 DOI: 10.1085/Jgp.200709896 |
0.686 |
|
| 2007 |
Qiu A, Min SH, Jansen M, Malhotra U, Tsai E, Cabelof DC, Matherly LH, Zhao R, Akabas MH, Goldman ID. Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction. American Journal of Physiology. Cell Physiology. 293: C1669-78. PMID 17898134 DOI: 10.1152/Ajpcell.00202.2007 |
0.528 |
|
| 2007 |
Rosen A, Bali M, Horenstein J, Akabas MH. Channel opening by anesthetics and GABA induces similar changes in the GABAA receptor M2 segment. Biophysical Journal. 92: 3130-9. PMID 17293408 DOI: 10.1529/Biophysj.106.094490 |
0.624 |
|
| 2007 |
Bali M, Akabas MH. The location of a closed channel gate in the GABAA receptor channel. The Journal of General Physiology. 129: 145-59. PMID 17227918 DOI: 10.1085/Jgp.200609639 |
0.629 |
|
| 2006 |
Qiu A, Jansen M, Sakaris A, Min SH, Chattopadhyay S, Tsai E, Sandoval C, Zhao R, Akabas MH, Goldman ID. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell. 127: 917-28. PMID 17129779 DOI: 10.1016/J.Cell.2006.09.041 |
0.511 |
|
| 2006 |
Reeves DC, Liebelt DA, Lakshmanan V, Roepe PD, Fidock DA, Akabas MH. Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms. Molecular and Biochemical Parasitology. 150: 288-99. PMID 17014918 DOI: 10.1016/J.Molbiopara.2006.09.001 |
0.753 |
|
| 2006 |
Jansen M, Akabas MH. State-dependent cross-linking of the M2 and M3 segments: functional basis for the alignment of GABAA and acetylcholine receptor M3 segments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4492-9. PMID 16641228 DOI: 10.1523/Jneurosci.0224-06.2006 |
0.567 |
|
| 2006 |
Akabas MH. Watching single protons bind. Nature Chemical Biology. 2: 128-30. PMID 16485003 DOI: 10.1038/nchembio0306-128 |
0.352 |
|
| 2005 |
Reeves DC, Jansen M, Bali M, Lemster T, Akabas MH. A role for the beta 1-beta 2 loop in the gating of 5-HT3 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9358-66. PMID 16221844 DOI: 10.1523/Jneurosci.1045-05.2005 |
0.792 |
|
| 2005 |
Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL. Emerging molecular mechanisms of general anesthetic action. Trends in Pharmacological Sciences. 26: 503-10. PMID 16126282 DOI: 10.1016/J.Tips.2005.08.006 |
0.36 |
|
| 2005 |
Bera AK, Akabas MH. Spontaneous thermal motion of the GABA(A) receptor M2 channel-lining segments. The Journal of Biological Chemistry. 280: 35506-12. PMID 16091360 DOI: 10.1074/Jbc.M504645200 |
0.581 |
|
| 2005 |
Jung S, Akabas MH, Harris RA. Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation. The Journal of Biological Chemistry. 280: 308-16. PMID 15522868 DOI: 10.1074/Jbc.M409871200 |
0.368 |
|
| 2005 |
Horenstein J, Riegelhaupt P, Akabas MH. Differential protein mobility of the gamma-aminobutyric acid, type A, receptor alpha and beta subunit channel-lining segments. The Journal of Biological Chemistry. 280: 1573-81. PMID 15522864 DOI: 10.1074/Jbc.M410881200 |
0.8 |
|
| 2005 |
Akabas MH, Bali M. GABAA receptor interactions with propofol: Binding site location and conformational changes International Congress Series. 1283: 3-8. DOI: 10.1016/j.ics.2005.07.014 |
0.497 |
|
| 2004 |
Akabas MH. GABAA receptor structure-function studies: a reexamination in light of new acetylcholine receptor structures. International Review of Neurobiology. 62: 1-43. PMID 15530567 DOI: 10.1016/S0074-7742(04)62001-0 |
0.406 |
|
| 2004 |
Bali M, Akabas MH. Defining the propofol binding site location on the GABAA receptor. Molecular Pharmacology. 65: 68-76. PMID 14722238 DOI: 10.1124/Mol.65.1.68 |
0.615 |
|
| 2004 |
Goren EN, Reeves DC, Akabas MH. Loose protein packing around the extracellular half of the GABA(A) receptor beta1 subunit M2 channel-lining segment. The Journal of Biological Chemistry. 279: 11198-205. PMID 14715650 DOI: 10.1074/jbc.M314050200 |
0.75 |
|
| 2002 |
Bera AK, Chatav M, Akabas MH. GABA(A) receptor M2-M3 loop secondary structure and changes in accessibility during channel gating. The Journal of Biological Chemistry. 277: 43002-10. PMID 12226083 DOI: 10.1074/Jbc.M206321200 |
0.56 |
|
| 2002 |
Williams DB, Akabas MH. Structural evidence that propofol stabilizes different GABA(A) receptor states at potentiating and activating concentrations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7417-24. PMID 12196563 DOI: 10.1523/Jneurosci.22-17-07417.2002 |
0.393 |
|
| 2002 |
Akabas MH. Probing CFTR channel structure and function using the substituted-cysteine-accessibility method. Methods in Molecular Medicine. 70: 159-74. PMID 11917520 DOI: 10.1385/1-59259-187-6:159 |
0.344 |
|
| 2001 |
Williams DB, Akabas MH. Evidence for distinct conformations of the two alpha 1 subunits in diazepam-bound GABA(A) receptors. Neuropharmacology. 41: 539-45. PMID 11587708 DOI: 10.1016/S0028-3908(01)00099-5 |
0.356 |
|
| 2001 |
Reeves DC, Goren EN, Akabas MH, Lummis SC. Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis. The Journal of Biological Chemistry. 276: 42035-42. PMID 11557761 DOI: 10.1074/Jbc.M106066200 |
0.754 |
|
| 2001 |
Horenstein J, Wagner DA, Czajkowski C, Akabas MH. Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment. Nature Neuroscience. 4: 477-85. PMID 11319555 DOI: 10.1038/87425 |
0.677 |
|
| 2000 |
Williams DB, Akabas MH. Benzodiazepines induce a conformational change in the region of the gamma-aminobutyric acid type A receptor alpha(1)-subunit M3 membrane-spanning segment. Molecular Pharmacology. 58: 1129-36. PMID 11040062 DOI: 10.1124/Mol.58.5.1129 |
0.396 |
|
| 2000 |
Akabas MH. Cystic fibrosis transmembrane conductance regulator. Structure and function of an epithelial chloride channel. The Journal of Biological Chemistry. 275: 3729-32. PMID 10660517 DOI: 10.1074/jbc.275.6.3729 |
0.346 |
|
| 1999 |
Williams DB, Akabas MH. Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors. Biophysical Journal. 77: 2563-74. PMID 10545357 DOI: 10.1016/S0006-3495(99)77091-8 |
0.365 |
|
| 1999 |
Guinamard R, Akabas MH. Arg352 is a major determinant of charge selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel. Biochemistry. 38: 5528-37. PMID 10220340 DOI: 10.1021/bi990155n |
0.365 |
|
| 1998 |
Akabas MH. Channel-lining residues in the M3 membrane-spanning segment of the cystic fibrosis transmembrane conductance regulator. Biochemistry. 37: 12233-40. PMID 9724537 DOI: 10.1021/bi980969o |
0.456 |
|
| 1998 |
Karlin A, Akabas MH. Substituted-cysteine accessibility method. Methods in Enzymology. 293: 123-45. PMID 9711606 DOI: 10.1016/S0076-6879(98)93011-7 |
0.608 |
|
| 1998 |
Horenstein J, Akabas MH. Location of a high affinity Zn2+ binding site in the channel of alpha1beta1 gamma-aminobutyric acidA receptors. Molecular Pharmacology. 53: 870-7. PMID 9584213 |
0.346 |
|
| 1997 |
Akabas MH, Cheung M, Guinamard R. Probing the structural and functional domains of the CFTR chloride channel. Journal of Bioenergetics and Biomembranes. 29: 453-63. PMID 9511930 DOI: 10.1023/A:1022482923122 |
0.457 |
|
| 1997 |
Cheung M, Akabas MH. Locating the anion-selectivity filter of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. The Journal of General Physiology. 109: 289-99. PMID 9089437 DOI: 10.1085/jgp.109.3.289 |
0.421 |
|
| 1996 |
Xu M, Akabas MH. Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit. The Journal of General Physiology. 107: 195-205. PMID 8833341 DOI: 10.1085/Jgp.107.2.195 |
0.397 |
|
| 1996 |
Cheung M, Akabas MH. Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment. Biophysical Journal. 70: 2688-95. PMID 8744306 DOI: 10.1016/S0006-3495(96)79838-7 |
0.452 |
|
| 1996 |
Sun ZP, Akabas MH, Goulding EH, Karlin A, Siegelbaum SA. Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating. Neuron. 16: 141-9. PMID 8562078 DOI: 10.1016/S0896-6273(00)80031-8 |
0.605 |
|
| 1995 |
Karlin A, Akabas MH. Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron. 15: 1231-44. PMID 8845149 DOI: 10.1016/0896-6273(95)90004-7 |
0.535 |
|
| 1995 |
Xu M, Covey DF, Akabas MH. Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants. Biophysical Journal. 69: 1858-67. PMID 8580329 DOI: 10.1016/S0006-3495(95)80056-1 |
0.371 |
|
| 1995 |
Akabas MH, Karlin A. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit. Biochemistry. 34: 12496-500. PMID 7547996 DOI: 10.1021/Bi00039A002 |
0.605 |
|
| 1994 |
Akabas MH, Kaufmann C, Archdeacon P, Karlin A. Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit. Neuron. 13: 919-27. PMID 7524560 DOI: 10.1016/0896-6273(94)90257-7 |
0.639 |
|
| 1994 |
Karlin A, Akabas MH, Czajkowski C, Kaufmann C, Stauffer D, Xu M. Structures involved in binding, gating, and conduction in nicotinic acetylcholine receptors. Renal Physiology and Biochemistry. 17: 184-6. PMID 7518954 DOI: 10.1159/000173814 |
0.691 |
|
| 1994 |
Akabas MH, Kaufmann C, Cook TA, Archdeacon P. Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 269: 14865-8. PMID 7515047 |
0.316 |
|
| 1993 |
Xu M, Akabas MH. Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution. The Journal of Biological Chemistry. 268: 21505-8. PMID 7691812 |
0.327 |
|
| 1992 |
Akabas MH, Stauffer DA, Xu M, Karlin A. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science (New York, N.Y.). 258: 307-10. PMID 1384130 DOI: 10.1126/Science.1384130 |
0.638 |
|
| 1991 |
Al-Awqati Q, Landry D, Akabas M, Redhead C, Edelman A, Edwards J. Purification of the epithelial C1 channel Advances in Experimental Medicine and Biology. 290: 235-240. PMID 1719761 DOI: 10.1007/978-1-4684-5934-0_23 |
0.363 |
|
| 1989 |
Cohen FS, Niles WD, Akabas MH. Fusion of phospholipid vesicles with a planar membrane depends on the membrane permeability of the solute used to create the osmotic pressure. The Journal of General Physiology. 93: 201-10. PMID 2539429 DOI: 10.1085/Jgp.93.2.201 |
0.753 |
|
| 1989 |
Landry DW, Akabas MH, Redhead C, Edelman A, Cragoe EJ, Al-Awqati Q. Purification and reconstitution of chloride channels from kidney and trachea. Science (New York, N.Y.). 244: 1469-72. PMID 2472007 DOI: 10.1126/Science.2472007 |
0.389 |
|
| 1984 |
Akabas MH, Cohen FS, Finkelstein A. Separation of the osmotically driven fusion event from vesicle-planar membrane attachment in a model system for exocytosis. The Journal of Cell Biology. 98: 1063-71. PMID 6699082 DOI: 10.1083/Jcb.98.3.1063 |
0.619 |
|
| 1984 |
Cohen FS, Akabas MH, Zimmerberg J, Finkelstein A. Parameters affecting the fusion of unilamellar phospholipid vesicles with planar bilayer membranes. The Journal of Cell Biology. 98: 1054-62. PMID 6699081 DOI: 10.1083/Jcb.98.3.1054 |
0.688 |
|
| 1982 |
Cohen FS, Akabas MH, Finkelstein A. Osmotic swelling of phospholipid vesicles causes them to fuse with a planar phospholipid bilayer membrane. Science (New York, N.Y.). 217: 458-60. PMID 6283637 DOI: 10.1126/Science.6283637 |
0.614 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2019 |
Sosa Y, Egbo D, Akabas MH. Impact of field isolate identified non-synonymous single nucleotide polymorphisms on Equilibrative Nucleoside Transporter 1 (PfENT1) inhibitor efficacy. Acs Infectious Diseases. PMID 31876139 DOI: 10.1021/acsinfecdis.9b00203 |
0.297 |
|
| 1990 |
Akabas M, Dodd J, Al-Awqati Q. Identification of electrophysiologically distinct subpopulations of rat taste cells The Journal of Membrane Biology. 114: 71-78. PMID 2157018 DOI: 10.1007/BF01869386 |
0.294 |
|
| 1990 |
Akabas MH. Mechanisms of chemosensory transduction in taste cells. International Review of Neurobiology. 32: 241-79. PMID 1706688 DOI: 10.1016/S0074-7742(08)60585-1 |
0.288 |
|
| 2016 |
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, et al. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. Plos Pathogens. 12: e1005763. PMID 27467575 DOI: 10.1371/Journal.Ppat.1005763 |
0.286 |
|
| 2023 |
Dillague C, Akabas MH. Putative purine nucleoside interacting residues in the malaria parasite purine uptake transporter PfENT1 are critical for transporter function. Plos One. 18: e0293923. PMID 38113238 DOI: 10.1371/journal.pone.0293923 |
0.25 |
|
| 1988 |
Akabas MH, Dodd J, Al-Awqati Q. A bitter substance induces a rise in intracellular calcium in a subpopulation of rat taste cells. Science (New York, N.Y.). 242: 1047-50. PMID 3194756 DOI: 10.1126/Science.3194756 |
0.225 |
|
| 2004 |
Akabas MH. Na+/Ca2+ exchange inhibitors: potential drugs to mitigate the severity of ischemic injury. Molecular Pharmacology. 66: 8-10. PMID 15213290 DOI: 10.1124/mol.104.000232. |
0.202 |
|
| 2010 |
Brass LF, Akabas MH, Burnley LD, Engman DM, Wiley CA, Andersen OS. Are MD-PhD programs meeting their goals? An analysis of career choices made by graduates of 24 MD-PhD programs. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 692-701. PMID 20186033 DOI: 10.1097/Acm.0B013E3181D3Ca17 |
0.202 |
|
| 2019 |
Brass LF, Akabas MH. The national MD-PhD program outcomes study: Relationships between medical specialty, training duration, research effort, and career paths. Jci Insight. 4. PMID 31578310 DOI: 10.1172/Jci.Insight.133009 |
0.198 |
|
| 2020 |
von Kaeppler EP, Akabas MH, Brass LF, Amanatullah DF. MD-PhD Graduates Remain Underrepresented in Orthopaedic Surgery: National MD-PhD Program Outcome Survey Update. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 32198793 DOI: 10.1002/Jor.24669 |
0.196 |
|
| 2019 |
Akabas MH, Brass LF. The national MD-PhD program outcomes study: Outcomes variation by sex, race, and ethnicity. Jci Insight. 4. PMID 31578303 DOI: 10.1172/Jci.Insight.133010 |
0.195 |
|
| 2017 |
Harding CV, Akabas MH, Andersen OS. History and Outcomes of 50 Years of Physician-Scientist Training in Medical Scientist Training Programs. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 28658019 DOI: 10.1097/Acm.0000000000001779 |
0.193 |
|
| 2011 |
Brass LF, Andersen OS, Akabas MH. In reply Academic Medicine. 86: 277-278. DOI: 10.1097/Acm.0B013E3182092701 |
0.188 |
|
| 2016 |
Kerrigan N, Akabas MH, Betzler TF, Castaldi M, Kelly MS, Levy AS, Reichgott MJ, Ruberman L, Dolan SM. Implementing competency based admissions at the Albert Einstein College of Medicine. Medical Education Online. 21: 30000. PMID 26847852 DOI: 10.3402/Meo.V21.30000 |
0.187 |
|
| 2014 |
Akabas MH, Brass LF. A closer look at attrition in MD-PhD programs. Academic Medicine : Journal of the Association of American Medical Colleges. 89: 958. PMID 24979155 DOI: 10.1097/Acm.0000000000000299 |
0.177 |
|
| 2018 |
Harding CV, Akabas MH, Andersen OS. In Reply to Sun et al. Academic Medicine : Journal of the Association of American Medical Colleges. 93: 150-151. PMID 29377855 DOI: 10.1097/Acm.0000000000002036 |
0.171 |
|
| 2016 |
Deniskin R, Frame IJ, Sosa Y, Akabas MH. Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development International Journal For Parasitology: Drugs and Drug Resistance. 6: 1-11. DOI: 10.1016/j.ijpddr.2015.11.003 |
0.158 |
|
| 2022 |
Brass LF, Fitzsimonds RM, Akabas MH. Gaps between college and starting an MD-PhD program are adding years to physician-scientist training time. Jci Insight. 7. PMID 35315357 DOI: 10.1172/jci.insight.156168 |
0.038 |
|
| 2022 |
Gallagher EJ, Rockey DC, Kontos CD, Vyas JM, Brass LF, Hu PJ, Isales CM, Ajijola OA, Rathmell WK, Conlin PR, Baiocchi RA, Kazmierczak BI, Akabas MH, Williams CS. Pearls of wisdom for aspiring physician-scientist residency applicants and program directors. Jci Insight. 7. PMID 35315364 DOI: 10.1172/jci.insight.158467 |
0.038 |
|
| 2024 |
Williams DKA, Christophers B, Keyes T, Kumar R, Granovetter MC, Adigun A, Olivera J, Pura-Bryant J, Smith C, Okafor C, Shibre M, Daye D, Akabas MH. Sociodemographic factors and research experience impact MD-PhD program acceptance. Jci Insight. 9. PMID 38329127 DOI: 10.1172/jci.insight.176146 |
0.033 |
|
| 2021 |
Campbell ST, Orner EP, Reyes Gil M, Fox AS, Goldstein DY, Wolgast LR, Cadoff EM, Freedman VH, Akabas MH, Prystowsky MB, Szymczak WA. Mater Artium Necessitas: The Birth of a COVID-19 Command Center. Academic Pathology. 8: 23742895211015347. PMID 34046523 DOI: 10.1177/23742895211015347 |
0.032 |
|
| 2016 |
Kerrigan N, Akabas MH, Betzler TF, Castaldi M, Kelly MS, Levy AS, Reichgott MJ, Ruberman L, Dolan SM. Implementing competency based admissions at the Albert Einstein College of Medicine. Medical Education Online. 21: 30000. PMID 28165985 DOI: 10.3402/meo.v21.30000 |
0.03 |
|
| 2023 |
Brass LF, Thalji N, Hodge DQ, Akabas MH. Physician-Scientists in Anesthesiology: The All Too Empty Pipeline. Anesthesia and Analgesia. 137: 725-727. PMID 37712461 DOI: 10.1213/ANE.0000000000006648 |
0.015 |
|
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