Aaron M. Kempema, Ph.D. - Publications

Affiliations: 
Chemistry Iowa State University, Ames, IA, United States 
Area:
Organic Chemistry

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Widen JC, Kempema AM, Baur JW, Skopec HM, Edwards JT, Brown TJ, Brown DA, Meece FA, Harki DA. Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles. Chemmedchem. PMID 29349898 DOI: 10.1002/Cmdc.201700752  0.685
2018 Widen JC, Kempema AM, Baur JW, Skopec HM, Edwards JT, Brown TJ, Brown DA, Meece FA, Harki DA. Front Cover: Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles (ChemMedChem 4/2018) Chemmedchem. 13: 288-288. DOI: 10.1002/Cmdc.201800079  0.679
2017 Widen JC, Kempema AM, Villalta PW, Harki DA. Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile. Acs Chemical Biology. 12: 102-113. PMID 28103680 DOI: 10.1021/Acschembio.6B00751  0.773
2016 Sachan A, Ilgu M, Kempema AM, Kraus GA, Nilsen-Hamilton M. Specificity and ligand affinities of the cocaine aptamer; impact of structural features and physiological NaCl. Analytical Chemistry. PMID 27348073 DOI: 10.1021/Acs.Analchem.6B01633  0.435
2015 Kerr JP, Robison P, Shi G, Bogush AI, Kempema AM, Hexum JK, Becerra N, Harki DA, Martin SS, Raiteri R, Prosser BL, Ward CW. Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle. Nature Communications. 6: 8526. PMID 26446751 DOI: 10.1038/Ncomms9526  0.606
2015 Kempema AM, Widen JC, Hexum JK, Andrews TE, Wang D, Rathe SK, Meece FA, Noble KE, Sachs Z, Largaespada DA, Harki DA. Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues. Bioorganic & Medicinal Chemistry. 23: 4737-45. PMID 26088334 DOI: 10.1016/J.Bmc.2015.05.037  0.631
2015 Hexum JK, Becker CM, Kempema AM, Ohlfest JR, Largaespada DA, Harki DA. Parthenolide prodrug LC-1 slows growth of intracranial glioma. Bioorganic & Medicinal Chemistry Letters. 25: 2493-5. PMID 25978958 DOI: 10.1016/J.Bmcl.2015.04.058  0.598
2015 Brand LJ, Olson ME, Ravindranathan P, Guo H, Kempema AM, Andrews TE, Chen X, Raj GV, Harki DA, Dehm SM. EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer. Oncotarget. 6: 3811-24. PMID 25669987 DOI: 10.18632/Oncotarget.2924  0.727
2015 Kerr JP, Prosser BL, Shi G, Robison P, Kempema AM, Hexum JK, Harki DA, Martin SS, Raiteri R, Ward CW. Post-Translational Modification of Tubulin Amplifies X-ROS Signaling in Striated Muscle Biophysical Journal. 108: 592a. DOI: 10.1016/J.Bpj.2014.11.3226  0.632
2014 Kraus GA, Guney T, Kempema A, Hyman JM, Parvin B. Efficient synthesis of fluorescent rosamines: Multifunctional platforms for cellular imaging Tetrahedron Letters. 55: 1549-1551. DOI: 10.1016/J.Tetlet.2014.01.067  0.715
2012 Kraus GA, Gupta V, Kempema A. New approach to flavonols via base-mediated cyclization: Total synthesis of 3,5,6,7-tetramethoxyflavone Synlett. 385-388. DOI: 10.1055/S-0031-1290207  0.586
2012 Kraus GA, Gupta V, Kempema A. ChemInform Abstract: New Approach to Flavonols via Base-Mediated Cyclization: Total Synthesis of 3,5,6,7-Tetramethoxyflavone Cheminform. 43: no-no. DOI: 10.1002/chin.201223196  0.425
2010 Kraus GA, Kempema A. Synthesis of azafluorenone antimicrobial agents. Journal of Natural Products. 73: 1967-8. PMID 20964320 DOI: 10.1021/Np100536A  0.467
2010 Kraus GA, Kempema A. A direct synthesis of racemic 1,3,4,5-tetragalloylapiitol Synthesis. 389-391. DOI: 10.1055/S-0029-1217123  0.463
2009 Kraus GA, Yuan Y, Kempema A. A convenient synthesis of Type A procyanidins. Molecules (Basel, Switzerland). 14: 807-15. PMID 19223829 DOI: 10.3390/Molecules14020807  0.45
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