Lena G. Gerwick, Ph.D. - Publications

Affiliations: 
Oregon State University, Corvallis, OR 
Area:
Comparative immunology, parasitology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yang JM, Liu YY, Yang WC, Ma XX, Nie YY, Glukhov E, Gerwick L, Gerwick WH, Lei XL, Zhang Y. An anti-inflammatory isoflavone from soybean inoculated with a marine fungus C23-3. Bioscience, Biotechnology, and Biochemistry. 1-8. PMID 32434451 DOI: 10.1080/09168451.2020.1764838  0.303
2019 Cao L, Gurevich A, Alexander KL, Naman CB, Leão T, Glukhov E, Luzzatto-Knaan T, Vargas F, Quinn R, Bouslimani A, Nothias LF, Singh NK, Sanders JG, Benitez RAS, Thompson LR, ... ... Gerwick L, et al. MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. Cell Systems. PMID 31629686 DOI: 10.1016/J.Cels.2019.09.004  0.322
2019 Yu HB, Glukhov E, Li Y, Iwasaki A, Gerwick L, Dorrestein PC, Jiao BH, Gerwick WH. Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium . Journal of Natural Products. PMID 31468974 DOI: 10.1021/Acs.Jnatprod.9B00549  0.321
2019 Moss NA, Seiler G, Leão TF, Castro-Falcón G, Gerwick L, Hughes CC, Gerwick WH. Nature's combinatorial biosynthesis produces vatiamides A-F. Angewandte Chemie (International Ed. in English). PMID 31071229 DOI: 10.1002/Anie.201902571  0.338
2018 Moss NA, Leao T, Rankin M, McCullough TM, Qu P, Korobeynikov A, Smith JL, Gerwick L, Gerwick WH. Ketoreductase domain dysfunction expands chemodiversity: malyngamide biosynthesis in the cyanobacterium Okeania hirsuta. Acs Chemical Biology. PMID 30444349 DOI: 10.1021/Acschembio.8B00910  0.38
2018 Moss NA, Leao T, Glukhov E, Gerwick L, Gerwick WH. Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria. Methods in Enzymology. 604: 3-43. PMID 29779657 DOI: 10.1016/Bs.Mie.2018.02.014  0.313
2018 Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. Acs Chemical Biology. PMID 29701944 DOI: 10.1021/Acschembio.8B00252  0.306
2018 Tao Y, Li P, Zhang D, Glukhov E, Gerwick L, Zhang C, Murray TF, Gerwick WH. The Samholides, Swinholide Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. The Journal of Organic Chemistry. PMID 29457979 DOI: 10.1021/Acs.Joc.8B00028  0.312
2018 Shao CL, Mou XF, Cao F, Spadafora C, Glukhov E, Gerwick L, Wang CY, Gerwick WH. Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group. Journal of Natural Products. PMID 29327931 DOI: 10.1021/Acs.Jnatprod.7B00917  0.318
2017 Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. Journal of Natural Products. PMID 29215273 DOI: 10.1021/Acs.Jnatprod.7B00734  0.36
2017 Luzzatto Knaan T, Garg N, Wang M, Glukhov E, Peng Y, Ackermann G, Amir A, Duggan BM, Ryazanov S, Gerwick L, Knight R, Alexandrov T, Bandeira N, Gerwick WH, Dorrestein PC. Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. Elife. 6. PMID 28492366 DOI: 10.7554/Elife.24214  0.329
2017 Kinnel RB, Esquenazi E, Leao T, Moss N, Mevers E, Pereira AR, Monroe EA, Korobeynikov A, Murray TF, Sherman D, Gerwick L, Dorrestein PC, Gerwick WH. A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens. Journal of Natural Products. PMID 28448144 DOI: 10.1021/Acs.Jnatprod.7B00019  0.382
2017 Leao T, Castelão G, Korobeynikov A, Monroe EA, Podell S, Glukhov E, Allen EE, Gerwick WH, Gerwick L. Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265051 DOI: 10.1073/Pnas.1618556114  0.336
2016 Bertin MJ, Vulpanovici A, Monroe EA, Korobeynikov A, Sherman DH, Gerwick L, Gerwick WH. The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide. Chembiochem : a European Journal of Chemical Biology. 17: 164-73. PMID 26769357 DOI: 10.1002/Cbic.201500467  0.353
2016 Kleigrewe K, Gerwick L, Sherman DH, Gerwick WH. Unique marine derived cyanobacterial biosynthetic genes for chemical diversity. Natural Product Reports. PMID 26758451 DOI: 10.1039/C5Np00097A  0.377
2015 Moss NA, Bertin MJ, Kleigrewe K, Leão TF, Gerwick L, Gerwick WH. Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery. Journal of Industrial Microbiology & Biotechnology. PMID 26578313 DOI: 10.1007/S10295-015-1705-7  0.344
2015 Boudreau PD, Monroe EA, Mehrotra S, Desfor S, Korobeynikov A, Sherman DH, Murray TF, Gerwick L, Dorrestein PC, Gerwick WH. Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows. Plos One. 10: e0133297. PMID 26222584 DOI: 10.1371/Journal.Pone.0133297  0.355
2015 Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH. Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. Journal of Natural Products. PMID 26149623 DOI: 10.1021/Acs.Jnatprod.5B00301  0.353
2015 Navarro G, Cummings S, Lee J, Moss N, Glukhov E, Valeriote FA, Gerwick L, Gerwick WH. Isolation of Polycavernoside D from a Marine Cyanobacterium Environmental Science & Technology Letters. 2: 166-170. DOI: 10.1021/Acs.Estlett.5B00116  0.341
2014 Micallef ML, Sharma D, Bunn BM, Gerwick L, Viswanathan R, Moffitt MC. Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria. Bmc Microbiology. 14: 213. PMID 25198896 DOI: 10.1186/S12866-014-0213-7  0.332
2014 Coates RC, Podell S, Korobeynikov A, Lapidus A, Pevzner P, Sherman DH, Allen EE, Gerwick L, Gerwick WH. Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways. Plos One. 9: e85140. PMID 24475038 DOI: 10.1371/Journal.Pone.0085140  0.302
2013 Della Sala G, Hochmuth T, Costantino V, Teta R, Gerwick W, Gerwick L, Piel J, Mangoni A. Polyketide genes in the marine sponge Plakortis simplex: A new group of mono-modular type I polyketide synthases from sponge symbionts Environmental Microbiology Reports. 5: 809-818. PMID 24249289 DOI: 10.1111/1758-2229.12081  0.337
2013 Sanchez LM, Knudsen GM, Helbig C, De Muylder G, Mascuch SM, Mackey ZB, Gerwick L, Clayton C, McKerrow JH, Linington RG. Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of Natural Products. 76: 630-41. PMID 23445522 DOI: 10.1021/Np300834Q  0.306
2013 Gerwick L, Boudreau P, Choi H, Mascuch S, Villa FA, Balunas MJ, Malloy KL, Teasdale ME, Rowley DC, Gerwick WH. Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites Phytochemistry Reviews. 12: 459-465. DOI: 10.1007/S11101-012-9237-5  0.599
2012 McCarthy JG, Eisman EB, Kulkarni S, Gerwick L, Gerwick WH, Wipf P, Sherman DH, Smith JL. Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. Acs Chemical Biology. 7: 1994-2003. PMID 22991895 DOI: 10.1021/Cb300385M  0.326
2012 Choi H, Mascuch SJ, Villa FA, Byrum T, Teasdale ME, Smith JE, Preskitt LB, Rowley DC, Gerwick L, Gerwick WH. Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships. Chemistry & Biology. 19: 589-98. PMID 22633410 DOI: 10.1016/J.Chembiol.2012.03.014  0.597
2012 Kim JW, Gerwick L, Park CI. Molecular identification and expression analysis of two distinct BPI/LBPs (bactericidal permeability-increasing protein/LPS-binding protein) from rock bream, Oplegnathus fasciatus Fish and Shellfish Immunology. 33: 75-84. PMID 22521422 DOI: 10.1016/J.Fsi.2012.04.003  0.332
2012 Jones AC, Ottilie S, Eustáquio AS, Edwards DJ, Gerwick L, Moore BS, Gerwick WH. Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A. The Febs Journal. 279: 1243-51. PMID 22314229 DOI: 10.1111/J.1742-4658.2012.08517.X  0.37
2012 Carland TM, Locke JB, Nizet V, Gerwick L. Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Developmental and Comparative Immunology. 36: 31-8. PMID 21683091 DOI: 10.1016/J.Dci.2011.05.013  0.331
2012 Monroe E, Choi H, Lesin V, Sirotkin A, Dvorkin M, Pevzner P, Gerwick W, Gerwick L. Genomic insights into secondary metabolism of the natural product-rich cyanobacterium Moorea bouillonii Planta Medica. 78. DOI: 10.1055/S-0032-1320287  0.302
2011 Engene N, Choi H, Esquenazi E, Byrum T, Villa FA, Cao Z, Murray TF, Dorrestein PC, Gerwick L, Gerwick WH. Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera. Journal of Natural Products. 74: 1737-43. PMID 21751786 DOI: 10.1021/Np200236C  0.335
2011 Jones AC, Monroe EA, Podell S, Hess WR, Klages S, Esquenazi E, Niessen S, Hoover H, Rothmann M, Lasken RS, Yates JR, Reinhardt R, Kube M, Burkart MD, Allen EE, ... ... Gerwick L, et al. Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proceedings of the National Academy of Sciences of the United States of America. 108: 8815-20. PMID 21555588 DOI: 10.1073/Pnas.1101137108  0.35
2011 Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH. Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage. Plos One. 6: e18565. PMID 21533272 DOI: 10.1371/Journal.Pone.0018565  0.36
2011 Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, et al. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Applied and Environmental Microbiology. 77: 3617-25. PMID 21498757 DOI: 10.1128/Aem.00038-11  0.382
2010 Jones AC, Monroe EA, Eisman EB, Gerwick L, Sherman DH, Gerwick WH. The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria. Natural Product Reports. 27: 1048-65. PMID 20442916 DOI: 10.1039/C000535E  0.359
2010 Villa FA, Gerwick L. Marine natural product drug discovery: Leads for treatment of inflammation, cancer, infections, and neurological disorders. Immunopharmacology and Immunotoxicology. 32: 228-37. PMID 20441539 DOI: 10.3109/08923970903296136  0.305
2010 Carland TM, Gerwick L. The C1q domain containing proteins: Where do they come from and what do they do? Developmental and Comparative Immunology. 34: 785-790. PMID 20214925 DOI: 10.1016/J.Dci.2010.02.014  0.342
2010 Villa FA, Lieske K, Gerwick L. Selective MyD88-dependent pathway inhibition by the cyanobacterial natural product malyngamide F acetate. European Journal of Pharmacology. 629: 140-6. PMID 20006962 DOI: 10.1016/J.Ejphar.2009.12.002  0.32
2009 Jones AC, Gerwick L, Gonzalez D, Dorrestein PC, Gerwick WH. Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins. Bmc Microbiology. 9: 247. PMID 19951434 DOI: 10.1186/1471-2180-9-247  0.385
2009 Gu L, Wang B, Kulkarni A, Gehret JJ, Lloyd KR, Gerwick L, Gerwick WH, Wipf P, HÃ¥kansson K, Smith JL, Sherman DH. Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. Journal of the American Chemical Society. 131: 16033-5. PMID 19835378 DOI: 10.1021/Ja9071578  0.311
2008 Simmons TL, Engene N, Ureña LD, Romero LI, Ortega-Barría E, Gerwick L, Gerwick WH. Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis. Journal of Natural Products. 71: 1544-50. PMID 18715036 DOI: 10.1021/Np800110E  0.326
2007 Momoda TS, Schwindt AR, Feist GW, Gerwick L, Bayne CJ, Schreck CB. Gene expression in the liver of rainbow trout, Oncorhynchus mykiss, during the stress response. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 2: 303-15. PMID 20483302 DOI: 10.1016/J.Cbd.2007.06.002  0.552
2007 Gerwick L, Corley-Smith G, Bayne CJ. Gene transcript changes in individual rainbow trout livers following an inflammatory stimulus. Fish & Shellfish Immunology. 22: 157-71. PMID 16762566 DOI: 10.1016/J.Fsi.2006.04.003  0.613
2006 Bayne CJ, Gerwick L, Wheeler PA, Thorgaard GH. Transcriptome profiles of livers and kidneys from three rainbow trout (Oncorhynchus mykiss) clonal lines distinguish stocks from three allopatric populations. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 1: 396-403. PMID 20483271 DOI: 10.1016/J.Cbd.2006.10.001  0.56
2005 Tilton SC, Gerwick LG, Hendricks JD, Rosato CS, Corley-Smith G, Givan SA, Bailey GS, Bayne CJ, Williams DE. Use of a rainbow trout oligonucleotide microarray to determine transcriptional patterns in aflatoxin B1-induced hepatocellular carcinoma compared to adjacent liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 319-30. PMID 16141433 DOI: 10.1093/Toxsci/Kfi309  0.56
2005 Gerwick L, Corley-Smith GE, Nakao M, Watson J, Bayne CJ. Intracranial injections induce local transcription of a gene encoding precerebellin-like protein Fish Physiology and Biochemistry. 31: 363-372. DOI: 10.1007/S10695-005-4588-0  0.593
2003 Fujiki K, Gerwick L, Bayne CJ, Mitchell L, Gauley J, Bols N, Dixon B. Molecular cloning and characterization of rainbow trout (Oncorhynchus mykiss) CCAAT/enhancer binding protein beta. Immunogenetics. 55: 253-61. PMID 12774179 DOI: 10.1007/S00251-003-0576-7  0.57
2002 Gerwick L, Steinhauer R, Lapatra S, Sandell T, Ortuno J, Hajiseyedjavadi N, Bayne CJ. The acute phase response of rainbow trout (Oncorhynchus mykiss) plasma proteins to viral, bacterial and fungal inflammatory agents. Fish & Shellfish Immunology. 12: 229-42. PMID 11931018 DOI: 10.1006/Fsim.2001.0367  0.581
2001 Bayne CJ, Gerwick L. The acute phase response and innate immunity of fish. Developmental and Comparative Immunology. 25: 725-43. PMID 11602193 DOI: 10.1016/S0145-305X(01)00033-7  0.616
2001 Bayne CJ, Gerwick L, Fujiki K, Nakao M, Yano T. Immune-relevant (including acute phase) genes identified in the livers of rainbow trout, Oncorhynchus mykiss, by means of suppression subtractive hybridization. Developmental and Comparative Immunology. 25: 205-17. PMID 11164886 DOI: 10.1016/S0145-305X(00)00057-4  0.606
2000 Gerwick L, Reynolds WS, Bayne CJ. A precerebellin-like protein is part of the acute phase response in rainbow trout, Oncorhynchus mykiss. Developmental and Comparative Immunology. 24: 597-607. PMID 10831794 DOI: 10.1016/S0145-305X(00)00016-1  0.598
1999 Gerwick L, Demers NE, Bayne CJ. Modulation of stress hormones in rainbow trout by means of anesthesia, sensory deprivation and receptor blockade. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 124: 329-34. PMID 10665382 DOI: 10.1016/S1095-6433(99)00126-9  0.535
1997 Gerwick L, Bayne CJ. KP2 Acute phase proteins in trout Developmental & Comparative Immunology. 21: 173. DOI: 10.1016/S0145-305X(97)88663-6  0.548
1997 Demers NE, Gerwick L, Bayne CJ. K5 2:45 Acute plasma hormonal changes within minutes of acute stress in rainbow trout Developmental & Comparative Immunology. 21: 169. DOI: 10.1016/S0145-305X(97)88656-9  0.526
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