Elizabeth Head - Related publications

Sanders Brown Center on Aging University of Kentucky, Lexington, KY 
brain aging and dementia
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Setti SE, Reed MN. Network activity changes in the pathophysiology of Alzheimer's disease: the role of aging and early entorhinal cortex dysfunction. Metabolic Brain Disease. PMID 34591222 DOI: 10.1007/s11011-021-00848-8   
2021 Kotredes KP, Oblak A, Pandey RS, Lin PB, Garceau D, Williams H, Uyar A, O'Rourke R, O'Rourke S, Ingraham C, Bednarycek D, Belanger M, Cope Z, Foley KE, Logsdon BA, et al. Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H. Frontiers in Aging Neuroscience. 13: 735524. PMID 34707490 DOI: 10.3389/fnagi.2021.735524   
2021 Kim JW, Byun MS, Yi D, Lee JH, Kim MJ, Jung G, Lee JY, Kang KM, Sohn CH, Lee YS, Kim YK, Lee DY, . Serum zinc levels and in vivo beta-amyloid deposition in the human brain. Alzheimer's Research & Therapy. 13: 190. PMID 34798903 DOI: 10.1186/s13195-021-00931-3   
2021 Yan XD, Qu XS, Yin J, Qiao J, Zhang J, Qi JS, Wu MN. Adiponectin Ameliorates Cognitive Behaviors and in vivo Synaptic Plasticity Impairments in 3xTg-AD Mice. Journal of Alzheimer's Disease : Jad. PMID 34806605 DOI: 10.3233/JAD-215063   
2021 Wang Q, Dong X, Zhang R, Zhao C. Flavonoids with Potential Anti-Amyloidogenic Effects as Therapeutic Drugs for Treating Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 34569961 DOI: 10.3233/JAD-210735   
2021 Li HJ, Wang TZ, Hou C, Liu HY, Zhang Y, Xue ZZ, Cai QC, Chen DM, Gao CW, Yang JL, Cong L, Chen Y, Yao Q, Zhu QS, Cao C. Artemether Attenuates Aβ25-35-Induced Cognitive Impairments by Downregulating Aβ, BACE1, mTOR and Tau Proteins. Clinical Laboratory. 67. PMID 34655202 DOI: 10.7754/Clin.Lab.2021.201212   
2021 Hu D, Liu C, Xia K, Abramowitz A, Wu G, . Characterizing the Resilience Effect of Neurodegeneration for the Mechanistic Pathway of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 34657890 DOI: 10.3233/JAD-215160   
2021 Buccellato FR, D'Anca M, Fenoglio C, Scarpini E, Galimberti D. Role of Oxidative Damage in Alzheimer's Disease and Neurodegeneration: From Pathogenic Mechanisms to Biomarker Discovery. Antioxidants (Basel, Switzerland). 10. PMID 34572985 DOI: 10.3390/antiox10091353   
2021 Daly T, Houot M, Barberousse A, Petit A, Epelbaum S. A Proposal to Make Biomedical Research into Alzheimer's Disease More Democratic Following an International Survey with Researchers. Journal of Alzheimer's Disease Reports. 5: 637-645. PMID 34632301 DOI: 10.3233/ADR-210030   
2021 D'Andrea L, Stringhi R, Di Luca M, Marcello E. Looking at Alzheimer's Disease Pathogenesis from the Nuclear Side. Biomolecules. 11. PMID 34572474 DOI: 10.3390/biom11091261   
2021 Yoon B, Guo T, Provost K, Korman D, Ward TJ, Landau SM, Jagust WJ, . Abnormal tau in amyloid PET negative individuals. Neurobiology of Aging. 109: 125-134. PMID 34715443 DOI: 10.1016/j.neurobiolaging.2021.09.019   
2021 Katsel P, Fam P, Tan W, Khan S, Gama-Sosa M, De Gasperi R, Roussos P, Robinson A, Cooper I, Schnaider-Beeri M, Haroutunian V. Engagement of vascular early response genes typifies mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34758195 DOI: 10.1002/alz.12481   
2021 Singh B, Singh H, Singh B, Kumar N, Rajput A, Sidhu D, Kaur A, Arora S, Kaur S. A comprehensive review on medicinal herbs and novel formulations for the prevention of Alzheimer's disease. Current Drug Delivery. PMID 34779370 DOI: 10.2174/1567201818666211015152733   
2021 Mandal PK, Samkaria A, Maroon JC. AD Hypotheses and Suggested Clinical Trials. Acs Chemical Neuroscience. PMID 34662512 DOI: 10.1021/acschemneuro.1c00627   
2021 Pang K, Jiang R, Zhang W, Yang Z, Li LL, Shimozawa M, Tambaro S, Mayer J, Zhang B, Li M, Wang J, Liu H, Yang A, Chen X, Liu J, et al. An App knock-in rat model for Alzheimer's disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments. Cell Research. PMID 34789895 DOI: 10.1038/s41422-021-00582-x   
2021 Cohen AD, Bruña R, Chang YF, Cheng Y, Doman J, Huppert T, Kim T, Maestu F, Roush RE, Snitz BE, Becker JT. Connectomics in Brain Aging and Dementia - The Background and Design of a Study of a Connectome Related to Human Disease. Frontiers in Aging Neuroscience. 13: 669490. PMID 34690734 DOI: 10.3389/fnagi.2021.669490   
2021 Yao L, Xu X, Xu Y, Li C, Xie F, Guo M, Liu C, Liu X. OGDHL Ameliorates Cognitive Impairment and Alzheimer's Disease-Like Pathology via Activating Wnt/β-catenin signaling in Alzheimer's Disease Mice. Behavioural Brain Research. 113673. PMID 34798170 DOI: 10.1016/j.bbr.2021.113673   
2021 Sanchez-Varo R, Sanchez-Mejias E, Fernandez-Valenzuela JJ, De Castro V, Mejias-Ortega M, Gomez-Arboledas A, Jimenez S, Sanchez-Mico MV, Trujillo-Estrada L, Moreno-Gonzalez I, Baglietto-Vargas D, Vizuete M, Davila JC, Vitorica J, Gutierrez A. Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis. Frontiers in Neuroscience. 15: 752594. PMID 34803589 DOI: 10.3389/fnins.2021.752594   
2021 Sawa M, Overk C, Becker A, Derse D, Albay R, Weldy K, Salehi A, Beach TG, Doran E, Head E, Yu YE, Mobley WC. Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34757693 DOI: 10.1002/alz.12463   
2021 Yin X, Zhou Z, Qiu Y, Fan X, Zhao C, Bao J, Liu C, Liu F, Qian W. SIRT1 Regulates Tau Expression and Tau Synaptic Pathology. Journal of Alzheimer's Disease : Jad. PMID 34602486 DOI: 10.3233/JAD-215118   
2021 Koenig LN, LaMontagne P, Glasser MF, Bateman R, Holtzman D, Yakushev I, Chhatwal J, Day GS, Jack C, Mummery C, Perrin RJ, Gordon BA, Morris JC, Shimony JS, Benzinger TLS, , et al. Regional age-related atrophy after screening for preclinical alzheimer disease. Neurobiology of Aging. 109: 43-51. PMID 34655980 DOI: 10.1016/j.neurobiolaging.2021.09.010   
2021 Stepanchuk AA, Barber PA, Lashley T, Joseph JT, Stys PK. Quantitative detection of grey and white matter amyloid pathology using a combination of K114 and CRANAD-3 fluorescence. Neurobiology of Disease. 161: 105540. PMID 34751140 DOI: 10.1016/j.nbd.2021.105540   
2021 Kumar M, Bansal N. A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer's Disease. Current Drug Targets. PMID 34792002 DOI: 10.2174/1389450122666211118125233   
2021 Lau WL, Fisher M, Fletcher E, DeCarli C, Troutt H, Corrada MM, Kawas C, Paganini-Hill A. Kidney Function Is Not Related to Brain Amyloid Burden on PET Imaging in The 90+ Study Cohort. Frontiers in Medicine. 8: 671945. PMID 34616751 DOI: 10.3389/fmed.2021.671945   
2021 Rodriguez-Vieitez E, Montal V, Sepulcre J, Lois C, Hanseeuw B, Vilaplana E, Schultz AP, Properzi MJ, Scott MR, Amariglio R, Papp KV, Marshall GA, Fortea J, Johnson KA, Sperling RA, et al. Association of cortical microstructure with amyloid-β and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults. Molecular Psychiatry. PMID 34588623 DOI: 10.1038/s41380-021-01290-z   
2021 Subramanian S, Krishna G, Sivakumar PT, Dahale AB, Kumar J S, Sinha P, Varghese M. Plasma neurofilament L to amyloid β42 ratio in differentiating Alzheimer's type from non-Alzheimer's dementia: A cross-sectional pilot study from India. Asian Journal of Psychiatry. 66: 102914. PMID 34741884 DOI: 10.1016/j.ajp.2021.102914   
2021 Song T, Song X, Zhu C, Patrick R, Skurla M, Santangelo I, Green M, Harper D, Ren B, Forester BP, Öngür D, Du F. Mitochondrial dysfunction, oxidative stress, neuroinflammation, and metabolic alterations in the progression of Alzheimer's disease: A meta-analysis of in vivo magnetic resonance spectroscopy studies. Ageing Research Reviews. 72: 101503. PMID 34751136 DOI: 10.1016/j.arr.2021.101503   
2021 Park YH, Pyun JM, Hodges A, Jang JW, Bice PJ, Kim S, Saykin AJ, Nho K, . Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease. Alzheimer's Research & Therapy. 13: 183. PMID 34732252 DOI: 10.1186/s13195-021-00919-z   
2021 Blanchard JW, Victor MB, Tsai LH. Dissecting the complexities of Alzheimer disease with in vitro models of the human brain. Nature Reviews. Neurology. PMID 34750588 DOI: 10.1038/s41582-021-00578-6   
2021 Minhas S, Khanum A, Alvi A, Riaz F, Khan SA, Alsolami F, A Khan M. Early MCI-to-AD Conversion Prediction Using Future Value Forecasting of Multimodal Features. Computational Intelligence and Neuroscience. 2021: 6628036. PMID 34608385 DOI: 10.1155/2021/6628036   
2021 Fernando KKM, Wijayasinghe YS. Sirtuins as Potential Therapeutic Targets for Mitigating Neuroinflammation Associated With Alzheimer's Disease. Frontiers in Cellular Neuroscience. 15: 746631. PMID 34630044 DOI: 10.3389/fncel.2021.746631   
2021 Li Y, Laws SM, Miles LA, Wiley JS, Huang X, Masters CL, Gu BJ. Genomics of Alzheimer's disease implicates the innate and adaptive immune systems. Cellular and Molecular Life Sciences : Cmls. PMID 34708251 DOI: 10.1007/s00018-021-03986-5   
2021 Nowak A, Kojder K, Zielonka-Brzezicka J, Wróbel J, Bosiacki M, Fabiańska M, Wróbel M, Sołek-Pastuszka J, Klimowicz A. The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer's Disease. Frontiers in Pharmacology. 12: 775034. PMID 34803717 DOI: 10.3389/fphar.2021.775034   
2021 Rezaee N, Fernando WMADB, Hone E, Sohrabi HR, Johnson SK, Gunzburg S, Martins RN. Potential of Sorghum Polyphenols to Prevent and Treat Alzheimer's Disease: A Review Article. Frontiers in Aging Neuroscience. 13: 729949. PMID 34690742 DOI: 10.3389/fnagi.2021.729949   
2021 Jia L, Yang J, Zhu M, Pang Y, Wang Q, Wei Q, Li Y, Li T, Li F, Wang Q, Li Y, Wei Y. A metabolite panel that differentiates Alzheimer's disease from other dementia types. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34786838 DOI: 10.1002/alz.12484   
2021 Ghosh P, Singh R, Ganeshpurkar A, Pokle AV, Singh RB, Singh SK, Kumar A. Cellular and molecular influencers of neuroinflammation in Alzheimer's disease: Recent concepts & roles. Neurochemistry International. 151: 105212. PMID 34656693 DOI: 10.1016/j.neuint.2021.105212   
2021 Pan JX, Sun D, Lee D, Xiong L, Ren X, Guo HH, Yao LL, Lu Y, Jung C, Xiong WC. Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence. Communications Biology. 4: 1326. PMID 34824365 DOI: 10.1038/s42003-021-02843-2   
2021 Cisternas P, Gherardelli C, Salazar P, Inestrosa NC. Disruption of Glucose Metabolism in Aged : A Sporadic Model of Alzheimer's Disease. Frontiers in Integrative Neuroscience. 15: 733007. PMID 34707484 DOI: 10.3389/fnint.2021.733007   
2021 Inkster AM, Duarte-Guterman P, Albert AY, Barha CK, Galea LAM, Robinson WP, . Are sex differences in cognitive impairment reflected in epigenetic age acceleration metrics? Neurobiology of Aging. 109: 192-194. PMID 34775209 DOI: 10.1016/j.neurobiolaging.2021.09.022   
2021 Zhang P, Lin S, Qiao J, Tu Y. Diagnosis of Alzheimer's Disease with Ensemble Learning Classifier and 3D Convolutional Neural Network. Sensors (Basel, Switzerland). 21. PMID 34833710 DOI: 10.3390/s21227634   
2021 Confer MP, Holcombe BM, Foes AG, Holmquist JM, Walker SC, Deb S, Ghosh A. Label-Free Infrared Spectroscopic Imaging Reveals Heterogeneity of β-Sheet Aggregates in Alzheimer's Disease. The Journal of Physical Chemistry Letters. 9662-9671. PMID 34590866 DOI: 10.1021/acs.jpclett.1c02306   
2021 Dansson HV, Stempfle L, Egilsdóttir H, Schliep A, Portelius E, Blennow K, Zetterberg H, Johansson FD, . Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer's disease. Alzheimer's Research & Therapy. 13: 151. PMID 34488882 DOI: 10.1186/s13195-021-00886-5   
2021 Tosun D, Demir Z, Veitch DP, Weintraub D, Aisen P, Jack CR, Jagust WJ, Petersen RC, Saykin AJ, Shaw LM, Trojanowski JQ, Weiner MW, . Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34647694 DOI: 10.1002/alz.12480   
2021 Chen L, Zhou YP, Liu HY, Gu JH, Zhou XF, Yue-Qin Z. Long-term oral administration of hyperoside ameliorates AD-related neuropathology and improves cognitive impairment in APP/PS1 transgenic mice. Neurochemistry International. 151: 105196. PMID 34601013 DOI: 10.1016/j.neuint.2021.105196   
2021 Lam S, Petit F, Hérard AS, Boluda S, Eddarkaoui S, Guillermier M, , Buée L, Duyckaerts C, Haïk S, Picq JL, Dhenain M. Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate. Acta Neuropathologica Communications. 9: 165. PMID 34641980 DOI: 10.1186/s40478-021-01266-8   
2021 Fu WY, Hung KW, Lau SF, Butt B, Yuen VW, Fu G, Chan IC, Ip FCF, Fu AKY, Ip NY. Rhynchophylline Administration Ameliorates Amyloid-β Pathology and Inflammation in an Alzheimer's Disease Transgenic Mouse Model. Acs Chemical Neuroscience. PMID 34738783 DOI: 10.1021/acschemneuro.1c00600   
2021 Hambali A, Kumar J, Hashim NFM, Maniam S, Mehat MZ, Cheema MS, Mustapha M, Adenan MI, Stanslas J, Hamid HA. Hypoxia-Induced Neuroinflammation in Alzheimer's Disease: Potential Neuroprotective Effects of . Frontiers in Physiology. 12: 712317. PMID 34721056 DOI: 10.3389/fphys.2021.712317   
2021 Lyu D, Li T, Lyu X. Resting-state functional reorganisation in Alzheimer's disease and amnestic mild cognitive impairment: protocol for a systematic review and meta-analysis. Bmj Open. 11: e049798. PMID 34642194 DOI: 10.1136/bmjopen-2021-049798   
2021 Liang X, Wu H, Colt M, Guo X, Pluimer B, Zeng J, Dong S, Zhao Z. Microglia and its genetics in Alzheimer's Disease. Current Alzheimer Research. PMID 34749609 DOI: 10.2174/1567205018666211105140732   
2021 Tan MS, Cheah PL, Chin AV, Looi LM, Chang SW. A review on omics-based biomarkers discovery for Alzheimer's disease from the bioinformatics perspectives: Statistical approach vs machine learning approach. Computers in Biology and Medicine. 139: 104947. PMID 34678481 DOI: 10.1016/j.compbiomed.2021.104947