Horst Hubertus Simon - Related publications

Affiliations: 
Uni Heidelberg, Heidelberg, Baden-Württemberg, Germany 
Area:
Parkinson's
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL. Revisiting astrocyte to neuron conversion with lineage tracing in vivo. Cell. PMID 34582787 DOI: 10.1016/j.cell.2021.09.005   
2021 Sarkar D, Shariq M, Dwivedi D, Krishnan N, Naumann R, Bhalla US, Ghosh HS. Adult brain neurons require continual expression of the schizophrenia-risk gene Tcf4 for structural and functional integrity. Translational Psychiatry. 11: 494. PMID 34564703 DOI: 10.1038/s41398-021-01618-x   
2021 Mishra AK, Dixit A. Dopaminergic Axons: Key Recitalists in Parkinson's Disease. Neurochemical Research. PMID 34637100 DOI: 10.1007/s11064-021-03464-1   
2021 Peng H, Xie P, Liu L, Kuang X, Wang Y, Qu L, Gong H, Jiang S, Li A, Ruan Z, Ding L, Yao Z, Chen C, Chen M, Daigle TL, et al. Morphological diversity of single neurons in molecularly defined cell types. Nature. 598: 174-181. PMID 34616072 DOI: 10.1038/s41586-021-03941-1   
2021 Barbuti PA, Ohnmacht J, Santos BFR, Antony PM, Massart F, Cruciani G, Dording CM, Pavelka L, Casadei N, Kwon YJ, Krüger R. Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports. 11: 21946. PMID 34754035 DOI: 10.1038/s41598-021-01505-x   
2021 An J, He Y, Yin J, Ding Z, Han Q, Chen Y, Wang Q, Chai Z, Yu J, Song L, Xiao B, Ma C. Temporal and spatial evolution of various functional neurons during demyelination induced by cuprizone. Journal of Neurophysiology. PMID 34669500 DOI: 10.1152/jn.00224.2021   
2021 Chen C, Mossman E, Malko P, McDonald D, Blain AP, Bone L, Erskine D, Filby A, Vincent AE, Hudson G, Reeve AK. Astrocytic Changes in Mitochondrial Oxidative Phosphorylation Protein Levels in Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 34779538 DOI: 10.1002/mds.28849   
2021 Lange J, Wood-Kaczmar A, Ali A, Farag S, Ghosh R, Parker J, Casey C, Uno Y, Kunugi A, Ferretti P, Andre R, Tabrizi SJ. Mislocalization of Nucleocytoplasmic Transport Proteins in Human Huntington's Disease PSC-Derived Striatal Neurons. Frontiers in Cellular Neuroscience. 15: 742763. PMID 34658796 DOI: 10.3389/fncel.2021.742763   
2021 de Rus Jacquet A, Tancredi JL, Lemire AL, DeSantis MC, Li WP, O'Shea EK. The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease. Elife. 10. PMID 34590578 DOI: 10.7554/eLife.73062   
2021 Sun X, Li W, Gong X, Hu G, Ge J, Wu J, Gao X. Investigating the Regulation of Neural Differentiation and Injury in PC12 Cells Using Microstructure Topographic Cues. Biosensors. 11. PMID 34677355 DOI: 10.3390/bios11100399   
2021 Blank N, Mayer M, Mass E. The development and physiological and pathophysiological functions of resident macrophages and glial cells. Advances in Immunology. 151: 1-47. PMID 34656287 DOI: 10.1016/bs.ai.2021.08.001   
2021 Richard EM, Bakhtiari S, Marsh APL, Kaiyrzhanov R, Wagner M, Shetty S, Pagnozzi A, Nordlie SM, Guida BS, Cornejo P, Magee H, Liu J, Norton BY, Webster RI, Worgan L, et al. Bi-allelic variants in SPATA5L1 lead to intellectual disability, spastic-dystonic cerebral palsy, epilepsy, and hearing loss. American Journal of Human Genetics. 108: 2006-2016. PMID 34626583 DOI: 10.1016/j.ajhg.2021.08.003   
2021 Salazar K, Espinoza F, Cerda-Gallardo G, Ferrada L, Magdalena R, Ramírez E, Ulloa V, Saldivia N, Troncoso N, Oviedo MJ, Barahona MJ, Martínez F, Nualart F. SVCT2 Overexpression and Ascorbic Acid Uptake Increase Cortical Neuron Differentiation, Which Is Dependent on Vitamin C Recycling between Neurons and Astrocytes. Antioxidants (Basel, Switzerland). 10. PMID 34573045 DOI: 10.3390/antiox10091413   
2021 Meltzer S, Santiago C, Sharma N, Ginty DD. The cellular and molecular basis of somatosensory neuron development. Neuron. PMID 34592169 DOI: 10.1016/j.neuron.2021.09.004   
2021 Palmer A, Epton S, Crawley E, Straface M, Gammon L, Edgar MM, Xu Y, Elahi S, Chin-Aleong J, Martin JE, Bishop CL, Knowles CH, Sanger GJ. Expression of p16 Within Myenteric Neurons of the Aged Colon: A Potential Marker of Declining Function. Frontiers in Neuroscience. 15: 747067. PMID 34690683 DOI: 10.3389/fnins.2021.747067   
2021 Whittaker DE, Oleari R, Gregory LC, Le Quesne Stabej P, Williams HJ, Torpiano JG, Formosa N, Cachia MJ, Field D, Lettieri A, Ocaka LA, Paganoni AJ, Rajabali SH, Riegman KL, De Martini LB, et al. A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. The Journal of Clinical Investigation. PMID 34730112 DOI: 10.1172/JCI141587   
2021 Yang H, Andersson U, Brines M. Neurons Are a Primary Driver of Inflammation via Release of HMGB1. Cells. 10. PMID 34685772 DOI: 10.3390/cells10102791   
2021 Van C, Condro MC, Ko HH, Hoang AQ, Zhu R, Lov K, Ricaflanca PT, Diep AL, Nguyen NNM, Lipshutz GS, MacKenzie-Graham A, Waschek JA. Targeted deletion of PAC1 receptors in retinal neurons enhances neuron loss and axonopathy in a model of multiple sclerosis and optic neuritis. Neurobiology of Disease. 105524. PMID 34610465 DOI: 10.1016/j.nbd.2021.105524   
2021 Anantha J, Goulding SR, Tuboly E, O'Mahony AG, Moloney GM, Lomansey G, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease. Molecular Neurobiology. PMID 34623600 DOI: 10.1007/s12035-021-02569-6   
2021 Michurina A, Sakib MS, Kerimoglu C, Krüger DM, Kaurani L, Islam MR, Joshi PD, Schröder S, Centeno TP, Zhou J, Pradhan R, Cha J, Xu X, Eichele G, Zeisberg EM, et al. Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes. The Embo Journal. e106459. PMID 34806773 DOI: 10.15252/embj.2020106459   
2021 Lee GS, Kwak G, Bae JH, Han JP, Nam SH, Lee JH, Song S, Kim GD, Park TS, Choi YK, Choi BO, Yeom SC. Morc2a p.S87L mutant mice develop peripheral and central neuropathies associated with neuronal DNA damage and apoptosis. Disease Models & Mechanisms. 14. PMID 34695197 DOI: 10.1242/dmm.049123   
2021 Hatayama K, Kim B, Chen X, Lim YP, Davidson JO, Bennet L, Gunn AJ, Stonestreet BS. Changes in Cellular Localization of Inter-Alpha Inhibitor Proteins after Cerebral Ischemia in the Near-Term Ovine Fetus. International Journal of Molecular Sciences. 22. PMID 34639091 DOI: 10.3390/ijms221910751   
2021 Kao TJ, Wang CY, Hsu TI, Wu YH, Chuang JY, Huang CC, Hsieh CT. TDP-43 is Essential for Eph Receptor-Class-Specific Spinal Motor Axon Trajectory into the Limb. Neuroscience Research. PMID 34687812 DOI: 10.1016/j.neures.2021.10.006   
2021 Dou YN, Wu X, Fei X, Fei Z. The neuroprotective effect of increased PINK1 expression following glutamate excitotoxicity in neuronal cells. Neuroscience. PMID 34798181 DOI: 10.1016/j.neuroscience.2021.11.020   
2021 Pourtoy-Brasselet S, Sciauvaud A, Boza-Moran MG, Cailleret M, Jarrige M, Polvèche H, Polentes J, Chevet E, Martinat C, Peschanski M, Aubry L. Human iPSC-derived neurons reveal early developmental alteration of neurite outgrowth in the late-occurring neurodegenerative Wolfram syndrome. American Journal of Human Genetics. 108: 2171-2185. PMID 34699745 DOI: 10.1016/j.ajhg.2021.10.001   
2021 Lee H, Lee JJ, Park NY, Dubey SK, Kim T, Ruan K, Lim SB, Park SH, Ha S, Kovlyagina I, Kim KT, Kim S, Oh Y, Kim H, Kang SU, et al. Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nature Neuroscience. PMID 34782793 DOI: 10.1038/s41593-021-00944-z   
2021 Mou Y, Dein J, Chen Z, Jagdale M, Li XJ. MFN2 Deficiency Impairs Mitochondrial Transport and Downregulates Motor Protein Expression in Human Spinal Motor Neurons. Frontiers in Molecular Neuroscience. 14: 727552. PMID 34602978 DOI: 10.3389/fnmol.2021.727552   
2021 Liu Y, Li H, Hu J, Wu Z, Meng J, Hayashi Y, Nakanishi H, Qing H, Ni J. Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury. Molecular Neurobiology. PMID 34762231 DOI: 10.1007/s12035-021-02594-5   
2021 Yeo M, Chen Y, Jiang C, Chen G, Wang K, Chandra S, Bortsov A, Lioudyno M, Zeng Q, Wang P, Wang Z, Busciglio J, Ji RR, Liedtke W. Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission. Nature Communications. 12: 6208. PMID 34707084 DOI: 10.1038/s41467-021-26270-3   
2021 Tamáš M, Pankratova S, Schjerling P, Soendenbroe C, Yeung CC, Pennisi CP, Jakobsen JR, Krogsgaard MR, Kjaer M, Mackey AL. Mutual stimulatory signaling between human myogenic cells and rat cerebellar neurons. Physiological Reports. 9: e15077. PMID 34713978 DOI: 10.14814/phy2.15077   
2021 Morrow JS, Stankewich MC. The Spread of Spectrin in Ataxia and Neurodegenerative Disease. Journal of Experimental Neurology. 2: 131-139. PMID 34528024   
2021 Peck LJ, Patel R, Diaz P, Wintle YM, Dickenson AH, Todd AJ, Calvo M, Bennett D. Studying independent knock-out mice reveals toxicity of exogenous LacZ to central nociceptor terminals and differential effects of Kv1.6 on acute and neuropathic pain sensation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34544832 DOI: 10.1523/JNEUROSCI.0187-21.2021   
2021 Zhu S, Stanslowsky N, Fernández-Trillo J, Mamo TM, Yu P, Kalmbach N, Ritter B, Eggenschwiler R, Ouwendijk WJD, Mzinza D, Tan L, Leffler A, Spohn M, Brown RJP, Kropp KA, et al. Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2. Stem Cell Research. 56: 102535. PMID 34607262 DOI: 10.1016/j.scr.2021.102535   
2021 Ma W, Yang JW, Wang XB, Luo T, Zhou L, Lagares A, Li H, Liang Z, Liu KP, Zang CH, Li CY, Wu Z, Guo JH, Zhou XF, Li LY. Negative regulation by proBDNF signaling of peripheral neurogenesis in the sensory ganglia of adult rats. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 144: 112273. PMID 34700232 DOI: 10.1016/j.biopha.2021.112273   
2021 Berghoff SA, Spieth L, Sun T, Hosang L, Depp C, Sasmita AO, Vasileva MH, Scholz P, Zhao Y, Krueger-Burg D, Wichert S, Brown ER, Michail K, Nave KA, Bonn S, et al. Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice. Cell Reports. 37: 109889. PMID 34706227 DOI: 10.1016/j.celrep.2021.109889   
2021 Company V, Moreno-Cerdá A, Andreu-Cervera A, Murcia-Ramón R, Almagro-García F, Echevarría D, Martínez S, Puelles E. Role in the Development of the Habenula and the Fasciculus Retroflexus. Frontiers in Cell and Developmental Biology. 9: 755729. PMID 34722541 DOI: 10.3389/fcell.2021.755729   
2021 Hong JY, Lee J, Kim H, Jeon WJ, Yeo C, Choi BR, Yoon JE, Shin JY, Kim JY, Ha IH. Neurotherapeutic Potential of Sibericus on Axon Regeneration and Growth Cone Reformation after HO-Induced Injury in Rat Primary Cortical Neurons. Biology. 10. PMID 34571710 DOI: 10.3390/biology10090833   
2021 Luo K, Wang L, Shen Y, She S, Cui Y, Liu K. TET3-mediated accumulation of DNA hydroxymethylation contributes to the activity-dependent gene expression of Rab3a in post-mitotic neurons. Journal of Integrative Neuroscience. 20: 529-539. PMID 34645086 DOI: 10.31083/j.jin2003057   
2021 Fearnley S, Raja R, Cloutier JF. Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Scientific Reports. 11: 19536. PMID 34599206 DOI: 10.1038/s41598-021-97768-5   
2021 Donohue JD, Amidon RF, Murphy TR, Wong AJ, Liu ED, Saab L, King AJ, Pae H, Ajayi MT, Anderson GR. Parahippocampal latrophilin-2 (ADGRL2) expression controls topographical presubiculum to entorhinal cortex circuit connectivity. Cell Reports. 37: 110031. PMID 34818557 DOI: 10.1016/j.celrep.2021.110031   
2021 Augusto-Oliveira M, Arrifano GP, Delage CI, Tremblay MÈ, Crespo-Lopez ME, Verkhratsky A. Plasticity of microglia. Biological Reviews of the Cambridge Philosophical Society. PMID 34549510 DOI: 10.1111/brv.12797   
2021 Xiang-Xin C, Tao T, Sen G, Han W, Xiao-Ming Z, Yong-Yue G, Chun-Hua H, Wei L. Knock-Down of CD24 in Astrocytes Aggravates Oxyhemoglobin-Induced Hippocampal Neuron Impairment. Neurochemical Research. PMID 34665391 DOI: 10.1007/s11064-021-03468-x   
2021 Trimmer JS. Genetically encoded intrabodies as high-precision tools to visualize and manipulate neuronal function. Seminars in Cell & Developmental Biology. PMID 34782184 DOI: 10.1016/j.semcdb.2021.11.004   
2021 Cho YH, Kim GH, Park JJ. Mitochondrial aconitase 1 regulates age-related memory impairment via autophagy/mitophagy-mediated neural plasticity in middle-aged flies. Aging Cell. e13520. PMID 34799973 DOI: 10.1111/acel.13520   
2021 Godin SK, Wagner J, Huang P, Bree D. The role of peripheral nerve signaling in endometriosis. Faseb Bioadvances. 3: 802-813. PMID 34632315 DOI: 10.1096/fba.2021-00063   
2021 Diaz-Garcia S, Ko VI, Vazquez-Sanchez S, Chia R, Arogundade OA, Rodriguez MJ, Traynor BJ, Cleveland D, Ravits J. Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 34618203 DOI: 10.1007/s00401-021-02374-4   
2021 Tremblay MÈ. Microglial functional alteration and increased diversity in the challenged brain: Insights into novel targets for intervention. Brain, Behavior, & Immunity - Health. 16: 100301. PMID 34589793 DOI: 10.1016/j.bbih.2021.100301   
2021 Fuchs J, Eickholt BJ. Precursor types predict the stability of neuronal branches. Journal of Cell Science. PMID 34766183 DOI: 10.1242/jcs.258983   
2021 Franjic D, Skarica M, Ma S, Arellano JI, Tebbenkamp ATN, Choi J, Xu C, Li Q, Morozov YM, Andrijevic D, Vrselja Z, Spajic A, Santpere G, Li M, Zhang S, et al. Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells. Neuron. PMID 34798047 DOI: 10.1016/j.neuron.2021.10.036   
2021 Haidar M, Viden A, Turner BJ. Advances in Gene Delivery Methods to Label and Modulate Activity of Upper Motor Neurons: Implications for Amyotrophic Lateral Sclerosis. Brain Sciences. 11. PMID 34573134 DOI: 10.3390/brainsci11091112