Brian G. Ciruna, Ph.D. - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Stem cell research, Molecular genetics, Developmental biology

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ali RQ, Meyer-Miner A, David-Rachel M, Lee FJH, Wilkins BJ, Karpen SJ, Ciruna B, Ghanekar A, Kamath BM. Loss of a cilia-associated gene, pkd1l1, causes biliary defects in zebrafish: Implications for Biliary Atresia Splenic Malformation. Disease Models & Mechanisms. PMID 37675454 DOI: 10.1242/dmm.049326  0.43
2023 Rebello D, Wohler E, Erfani V, Li G, Aguilera AN, Santiago-Cornier A, Zhao S, Hwang SW, Steiner RD, Zhang TJ, Gurnett CA, Raggio C, Wu N, Sobreira N, Giampietro PF, ... Ciruna B, et al. COL11A2 as a candidate gene for vertebral malformations and congenital scoliosis. Human Molecular Genetics. PMID 37462524 DOI: 10.1093/hmg/ddad117  0.338
2022 Jussila M, Boswell CW, Griffiths NW, Pumputis PG, Ciruna B. Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2. Nature Communications. 13: 5598. PMID 36151137 DOI: 10.1038/s41467-022-33322-9  0.416
2022 Meyer-Miner A, Van Gennip JLM, Henke K, Harris MP, Ciruna B. Resolving primary pathomechanisms driving idiopathic-like spinal curvature using a new scoliosis model. Iscience. 25: 105028. PMID 36105588 DOI: 10.1016/j.isci.2022.105028  0.301
2020 Tsatskis Y, Rosenfeld R, Pearson JD, Boswell C, Qu Y, Kim K, Fabian L, Mohammad A, Wang X, Robson MI, Krchma K, Wu J, Gonçalves J, Hodzic D, Wu S, ... ... Ciruna B, et al. The NEMP family supports metazoan fertility and nuclear envelope stiffness. Science Advances. 6: eabb4591. PMID 32923640 DOI: 10.1126/Sciadv.Abb4591  0.399
2020 Rose CD, Pompili D, Henke K, Van Gennip JLM, Meyer-Miner A, Rana R, Gobron S, Harris MP, Nitz M, Ciruna B. SCO-Spondin Defects and Neuroinflammation Are Conserved Mechanisms Driving Spinal Deformity across Genetic Models of Idiopathic Scoliosis. Current Biology : Cb. PMID 32386528 DOI: 10.1016/J.Cub.2020.04.020  0.444
2020 Hengel H, Bosso-Lefèvre C, Grady G, Szenker-Ravi E, Li H, Pierce S, Lebigot É, Tan TT, Eio MY, Narayanan G, Utami KH, Yau M, Handal N, Deigendesch W, Keimer R, ... ... Ciruna B, et al. Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy. Nature Communications. 11: 595. PMID 32001716 DOI: 10.1038/S41467-020-14360-7  0.391
2018 Van Gennip JLM, Boswell CW, Ciruna B. Neuroinflammatory signals drive spinal curve formation in zebrafish models of idiopathic scoliosis. Science Advances. 4: eaav1781. PMID 30547092 DOI: 10.1126/Sciadv.Aav1781  0.358
2018 Konjikusic MJ, Yeetong P, Boswell CW, Lee C, Roberson EC, Ittiwut R, Suphapeetiporn K, Ciruna B, Gurnett CA, Wallingford JB, Shotelersuk V, Gray RS. Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development. Plos Genetics. 14: e1007817. PMID 30475797 DOI: 10.1371/Journal.Pgen.1007817  0.475
2017 Jussila M, Ciruna B. Zebrafish models of non-canonical Wnt/planar cell polarity signalling: fishing for valuable insight into vertebrate polarized cell behavior. Wiley Interdisciplinary Reviews. Developmental Biology. 6. PMID 28304136 DOI: 10.1002/Wdev.267  0.502
2017 Boswell CW, Ciruna B. Understanding Idiopathic Scoliosis: A New Zebrafish School of Thought. Trends in Genetics : Tig. 33: 183-196. PMID 28174019 DOI: 10.1016/J.Tig.2017.01.001  0.382
2017 Bosso-Lefèvre C, Yu E, Grady G, Szenker E, Jamuar SS, Muriello M, Gunay-Aygun M, Koolen D, Lefeber D, Hengel H, Schoels L, Simpson M, Ciruna B, Reversade B. UGDH germline loss-of-function mutations cause epilepsy and global developmental delay Mechanisms of Development. 145: S26-S27. DOI: 10.1016/J.Mod.2017.04.016  0.325
2016 Grimes DT, Boswell CW, Morante NF, Henkelman RM, Burdine RD, Ciruna B. Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature. Science (New York, N.Y.). 352: 1341-4. PMID 27284198 DOI: 10.1126/Science.Aaf6419  0.434
2015 Lau K, Tao H, Liu H, Wen J, Sturgeon K, Sorfazlian N, Lazic S, Burrows JT, Wong MD, Li D, Deimling S, Ciruna B, Scott I, Simmons C, Henkelman RM, et al. Anisotropic stress orients remodelling of mammalian limb bud ectoderm. Nature Cell Biology. 17: 569-79. PMID 25893915 DOI: 10.1038/Ncb3156  0.367
2015 Carvajal-Gonzalez JM, Balmer S, Mendoza M, Dussert A, Collu G, Roman AC, Weber U, Ciruna B, Mlodzik M. The clathrin adaptor AP-1 complex and Arf1 regulate planar cell polarity in vivo. Nature Communications. 6: 6751. PMID 25849195 DOI: 10.1038/Ncomms7751  0.469
2014 Hayes M, Gao X, Yu LX, Paria N, Henkelman RM, Wise CA, Ciruna B. ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease. Nature Communications. 5: 4777. PMID 25182715 DOI: 10.1038/Ncomms5777  0.496
2014 Superina S, Borovina A, Ciruna B. Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry. Developmental Biology. 387: 154-66. PMID 24462977 DOI: 10.1016/J.Ydbio.2014.01.013  0.714
2013 Borovina A, Ciruna B. IFT88 plays a cilia- and PCP-independent role in controlling oriented cell divisions during vertebrate embryonic development. Cell Reports. 5: 37-43. PMID 24095732 DOI: 10.1016/J.Celrep.2013.08.043  0.724
2013 Pan YA, Freundlich T, Weissman TA, Schoppik D, Wang XC, Zimmerman S, Ciruna B, Sanes JR, Lichtman JW, Schier AF. Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (Cambridge, England). 140: 2835-46. PMID 23757414 DOI: 10.1242/Dev.094631  0.401
2013 Hayes M, Naito M, Daulat A, Angers S, Ciruna B. Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development. Development (Cambridge, England). 140: 1807-18. PMID 23533179 DOI: 10.1242/Dev.090183  0.587
2012 Schoenebeck JJ, Hutchinson SA, Byers A, Beale HC, Carrington B, Faden DL, Rimbault M, Decker B, Kidd JM, Sood R, Boyko AR, Fondon JW, Wayne RK, Bustamante CD, Ciruna B, et al. Variation of BMP3 contributes to dog breed skull diversity. Plos Genetics. 8: e1002849. PMID 22876193 DOI: 10.1371/Journal.Pgen.1002849  0.345
2012 Borovina A, Ciruna B. Investigating the link between PCP signalling and ciliogenesis during zebrafish development Cilia. 1. DOI: 10.1186/2046-2530-1-S1-O22  0.313
2011 Persaud A, Alberts P, Hayes M, Guettler S, Clarke I, Sicheri F, Dirks P, Ciruna B, Rotin D. Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function. The Embo Journal. 30: 3259-73. PMID 21765395 DOI: 10.1038/Emboj.2011.234  0.425
2011 Miyamoto T, Porazinski S, Wang H, Borovina A, Ciruna B, Shimizu A, Kajii T, Kikuchi A, Furutani-Seiki M, Matsuura S. Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates. Human Molecular Genetics. 20: 2058-70. PMID 21389084 DOI: 10.1093/Hmg/Ddr090  0.704
2011 Zhang X, Lu Z, Gelinas D, Ciruna B, Sun Y. Batch transfer of zebrafish embryos into multiwell plates Ieee Transactions On Automation Science and Engineering. 8: 625-632. DOI: 10.1109/Tase.2011.2121903  0.401
2010 Wyngaarden LA, Vogeli KM, Ciruna BG, Wells M, Hadjantonakis AK, Hopyan S. Oriented cell motility and division underlie early limb bud morphogenesis. Development (Cambridge, England). 137: 2551-8. PMID 20554720 DOI: 10.1242/Dev.046987  0.438
2010 Borovina A, Superina S, Voskas D, Ciruna B. Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. Nature Cell Biology. 12: 407-12. PMID 20305649 DOI: 10.1038/Ncb2042  0.717
2009 Yin C, Ciruna B, Solnica-Krezel L. Convergence and extension movements during vertebrate gastrulation. Current Topics in Developmental Biology. 89: 163-92. PMID 19737646 DOI: 10.1016/S0070-2153(09)89007-8  0.356
2009 Calarco JA, Superina S, O'Hanlon D, Gabut M, Raj B, Pan Q, Skalska U, Clarke L, Gelinas D, van der Kooy D, Zhen M, Ciruna B, Blencowe BJ. Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein. Cell. 138: 898-910. PMID 19737518 DOI: 10.1016/J.Cell.2009.06.012  0.421
2007 Bennett JT, Stickney HL, Choi WY, Ciruna B, Talbot WS, Schier AF. Maternal nodal and zebrafish embryogenesis. Nature. 450: E1-2; discussion E2-. PMID 17994032 DOI: 10.1038/Nature06314  0.425
2007 Wang W, Liu X, Gelinas D, Ciruna B, Sun Y. A fully automated robotic system for microinjection of zebrafish embryos. Plos One. 2: e862. PMID 17848993 DOI: 10.1371/Journal.Pone.0000862  0.373
2006 Zhao H, Yang Y, Partanen J, Ciruna BG, Rossant J, Robinson ML. Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice. Molecular Vision. 12: 15-25. PMID 16446698  0.535
2006 Ciruna B, Jenny A, Lee D, Mlodzik M, Schier AF. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature. 439: 220-4. PMID 16407953 DOI: 10.1038/Nature04375  0.515
2002 Ciruna B, Weidinger G, Knaut H, Thisse B, Thisse C, Raz E, Schier AF. Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America. 99: 14919-24. PMID 12397179 DOI: 10.1073/Pnas.222459999  0.432
2001 Ciruna B, Rossant J. FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Developmental Cell. 1: 37-49. PMID 11703922 DOI: 10.1016/S1534-5807(01)00017-X  0.602
2000 Saxton TM, Ciruna BG, Holmyard D, Kulkarni S, Harpal K, Rossant J, Pawson T. The SH2 tyrosine phosphatase shp2 is required for mammalian limb development. Nature Genetics. 24: 420-3. PMID 10742110 DOI: 10.1038/74279  0.673
1999 Ciruna BG, Rossant J. Expression of the T-box gene Eomesodermin during early mouse development. Mechanisms of Development. 81: 199-203. PMID 10330500 DOI: 10.1016/S0925-4773(98)00243-3  0.513
1999 Tropepe V, Sibilia M, Ciruna BG, Rossant J, Wagner EF, van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Developmental Biology. 208: 166-88. PMID 10075850 DOI: 10.1006/Dbio.1998.9192  0.51
1997 Ciruna BG, Schwartz L, Harpal K, Yamaguchi TP, Rossant J. Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. Development (Cambridge, England). 124: 2829-41. PMID 9226454  0.6
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