Stella E. Tsirka - Publications

Affiliations: 
Pharmacological Sciences Stony Brook University, Stony Brook, NY, United States 

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Li M, Thompson KK, Nissen JC, Hendrix D, Hurowitz JA, Tsirka SE. Lunar soil simulants alter macrophage survival and function. Journal of Applied Toxicology : Jat. PMID 31319435 DOI: 10.1002/jat.3827  0.8
2019 Son J, Mandracchia B, Caponegro MD, Tsirka SE, Jia S. BSSE: An open-source image processing tool for miniaturized microscopy. Optics Express. 27: 17620-17637. PMID 31252719 DOI: 10.1364/OE.27.017620  0.36
2019 Kyle J, Wu M, Gourzi S, Tsirka SE. Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition. Frontiers in Cellular Neuroscience. 13: 97. PMID 31001085 DOI: 10.3389/fncel.2019.00097  1
2018 Thompson KK, Nissen JC, Pretory A, Tsirka SE. Tuftsin Combines With Remyelinating Therapy and Improves Outcomes in Models of CNS Demyelinating Disease. Frontiers in Immunology. 9: 2784. PMID 30555470 DOI: 10.3389/fimmu.2018.02784  0.8
2018 Caponegro MD, Moffitt RA, Tsirka SE. Expression of neuropilin-1 is linked to glioma associated microglia and macrophages and correlates with unfavorable prognosis in high grade gliomas. Oncotarget. 9: 35655-35665. PMID 30479695 DOI: 10.18632/oncotarget.26273  0.36
2018 Caponegro MD, Torres LF, Rastegar C, Rath N, Anderson ME, Robinson JK, Tsirka SE. Pifithrin-μ modulates microglial activation and promotes histological recovery following spinal cord injury. Cns Neuroscience & Therapeutics. PMID 29962076 DOI: 10.1111/cns.13000  0.6
2018 Nissen JC, Thompson KK, West BL, Tsirka SE. Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery. Experimental Neurology. PMID 29803827 DOI: 10.1016/j.expneurol.2018.05.021  0.8
2018 Preston AN, Farr JD, O'Neill BK, Thompson KK, Tsirka SE, Laughlin ST. Visualizing the brain's astrocytes with diverse chemical scaffolds. Acs Chemical Biology. PMID 29733639 DOI: 10.1021/acschembio.8b00391  0.32
2018 Powell J, Mota F, Steadman D, Soudy C, Miyauchi JT, Crosby S, Jarvis A, Reisinge T, Winfield N, Evans G, Finniear A, Yelland T, Chou YT, Chan AWE, O'Leary A, ... ... Tsirka SE, et al. Small molecule neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGFβ) production in regulatory T-cells. Journal of Medicinal Chemistry. PMID 29648813 DOI: 10.1021/acs.jmedchem.8b00210  0.48
2018 Haj-Dahmane S, Shen RY, Elmes MW, Studholme K, Kanjiya MP, Bogdan D, Thanos PK, Miyauchi JT, Tsirka SE, Deutsch DG, Kaczocha M. Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531087 DOI: 10.1073/pnas.1721339115  0.48
2017 Miyauchi JT, Tsirka SE. Advances in immunotherapeutic research for glioma therapy. Journal of Neurology. PMID 29209782 DOI: 10.1007/s00415-017-8695-5  0.48
2017 Miyauchi JT, Caponegro MD, Chen D, Choi MK, Li M, Tsirka SE. Deletion of neuropilin 1 from microglia or bone marrow-derived macrophages slows glioma progression. Cancer Research. PMID 29097606 DOI: 10.1158/0008-5472.CAN-17-1435  0.48
2017 Bronstein R, Kyle J, Abraham AB, Tsirka SE. Neurogenic to Gliogenic Fate Transition Perturbed by Loss of HMGB2. Frontiers in Molecular Neuroscience. 10: 153. PMID 28588451 DOI: 10.3389/fnmol.2017.00153  0.8
2017 Thompson KK, Tsirka SE. The Diverse Roles of Microglia in the Neurodegenerative Aspects of Central Nervous System (CNS) Autoimmunity. International Journal of Molecular Sciences. 18. PMID 28245617 DOI: 10.3390/ijms18030504  0.32
2016 Lewis CS, Torres L, Miyauchi JT, Rastegar C, Patete JM, Smith JM, Wong SS, Tsirka SE. Absence of Cytotoxicity towards Microglia of Iron Oxide (α-Fe2O3) Nanorhombohedra. Toxicology Research. 5: 836-847. PMID 27274811 DOI: 10.1039/C5TX00421G  0.8
2016 Nissen JC, Tsirka SE. Tuftsin-driven experimental autoimmune encephalomyelitis recovery requires neuropilin-1. Glia. PMID 26880314 DOI: 10.1002/glia.22972  1
2016 Miyauchi JT, Chen D, Choi M, Nissen JC, Shroyer KR, Djordevic S, Zachary IC, Selwood D, Tsirka SE. Ablation of neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression. Oncotarget. PMID 26755653 DOI: 10.18632/oncotarget.6877  1
2015 Bukhari N, Burman PN, Hussein A, Demars MP, Sadahiro M, Brady DM, Tsirka SE, Russo SJ, Morishita H. Unmasking Proteolytic Activity for Adult Visual Cortex Plasticity by the Removal of Lynx1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12693-702. PMID 26377459 DOI: 10.1523/JNEUROSCI.4315-14.2015  1
2015 Torres L, Danver J, Ji K, Miyauchi JT, Chen D, Anderson ME, L West B, Robinson JK, Tsirka SE. Dynamic microglial modulation of spatial learning and social behavior. Brain, Behavior, and Immunity. PMID 26348580 DOI: 10.1016/j.bbi.2015.09.001  1
2015 Gao Z, Nissen JC, Legakis L, Tsirka SE. Nicotine modulates neurogenesis in the central canal during experimental autoimmune encephalomyelitis. Neuroscience. 297: 11-21. PMID 25813705 DOI: 10.1016/j.neuroscience.2015.03.031  1
2015 Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG. Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The Journal of Biological Chemistry. 290: 8711-21. PMID 25666611 DOI: 10.1074/jbc.M114.618447  1
2015 Harrington AD, Smirnov A, Tsirka SE, Schoonen MA. Metal-sulfide mineral ores, Fenton chemistry and disease--particle induced inflammatory stress response in lung cells. International Journal of Hygiene and Environmental Health. 218: 19-27. PMID 25107347 DOI: 10.1016/j.ijheh.2014.07.002  1
2014 Gao Z, Nissen JC, Ji K, Tsirka SE. The experimental autoimmune encephalomyelitis disease course is modulated by nicotine and other cigarette smoke components Plos One. 9. PMID 25250777 DOI: 10.1371/journal.pone.0107979  1
2014 Yao Y, Tsirka SE. Mouse monocyte chemoattractant protein 1 (MCP1) functions as a monomer. The International Journal of Biochemistry & Cell Biology. 55: 51-9. PMID 25130440 DOI: 10.1016/j.biocel.2014.08.002  0.32
2014 He Y, Yao Y, Tsirka SE, Cao Y. Cell-culture models of the blood-brain barrier Stroke. 45: 2514-2526. PMID 24938839 DOI: 10.1161/STROKEAHA.114.005427  1
2014 Yao Y, Tsirka SE. Monocyte chemoattractant protein-1 and the blood-brain barrier Cellular and Molecular Life Sciences. 71: 683-697. PMID 24051980 DOI: 10.1007/s00018-013-1459-1  1
2014 Yao Y, Tsirka SE. Mouse monocyte chemoattractant protein 1 (MCP1) functions as a monomer International Journal of Biochemistry and Cell Biology. 55: 51-59. DOI: 10.1016/j.biocel.2014.08.002  1
2013 Abraham AB, Bronstein R, Reddy AS, Maletic-Savatic M, Aguirre A, Tsirka SE. Aberrant neural stem cell proliferation and increased adult neurogenesis in mice lacking chromatin protein HMGB2. Plos One. 8: e84838. PMID 24391977 DOI: 10.1371/journal.pone.0084838  1
2013 Ji K, Miyauchi J, Tsirka SE. Microglia: An active player in the regulation of synaptic activity Neural Plasticity. 2013. PMID 24303218 DOI: 10.1155/2013/627325  1
2013 Nissen JC, Selwood DL, Tsirka SE. Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway Journal of Neurochemistry. 127: 394-402. PMID 24033337 DOI: 10.1111/jnc.12404  1
2013 Bronstein R, Torres L, Nissen JC, Tsirka SE. Culturing microglia from the neonatal and adult central nervous system. Journal of Visualized Experiments : Jove. PMID 23962915 DOI: 10.3791/50647  1
2013 Harrington AD, Tsirka SE, Schoonen MAA. Inflammatory stress response in A549 cells as a result of exposure to coal: Evidence for the role of pyrite in coal workers' pneumoconiosis pathogenesis Chemosphere. 93: 1216-1221. PMID 23895739 DOI: 10.1016/j.chemosphere.2013.06.082  1
2013 Abraham AB, Bronstein R, Chen EI, Koller A, Ronfani L, Maletic-Savatic M, Tsirka SE. Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells. Proteome Science. 11: 18. PMID 23621913 DOI: 10.1186/1477-5956-11-18  1
2013 Ji K, Akgul G, Wollmuth LP, Tsirka SE. Microglia actively regulate the number of functional synapses. Plos One. 8: e56293. PMID 23393609 DOI: 10.1371/journal.pone.0056293  1
2013 Louie E, Chen XF, Coomes A, Ji K, Tsirka S, Chen EI. Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis Oncogene. 32: 4064-4077. PMID 23001042 DOI: 10.1038/onc.2012.417  1
2012 Yao Y, Tsirka SE. Chemokines and their receptors in intracerebral hemorrhage. Translational Stroke Research. 3: 70-9. PMID 24323863 DOI: 10.1007/s12975-012-0155-z  0.32
2012 Hedhli N, Falcone DJ, Huang B, Cesarman-Maus G, Kraemer R, Zhai H, Tsirka SE, Santambrogio L, Hajjar KA. The annexin A2/S100A10 system in health and disease: Emerging paradigms Journal of Biomedicine and Biotechnology. 2012. PMID 23193360 DOI: 10.1155/2012/406273  1
2012 Ji K, Tsirka SE. Inflammation modulates expression of laminin in the central nervous system following ischemic injury Journal of Neuroinflammation. 9. PMID 22759265 DOI: 10.1186/1742-2094-9-159  1
2012 Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM. P53 opens the mitochondrial permeability transition pore to trigger necrosis Cell. 149: 1536-1548. PMID 22726440 DOI: 10.1016/j.cell.2012.05.014  1
2012 Emmetsberger J, Tsirka SE. Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury Neurobiology of Disease. 47: 295-309. PMID 22613732 DOI: 10.1016/j.nbd.2012.05.001  1
2012 Wu M, Nissen JC, Chen EI, Tsirka SE. Tuftsin promotes an anti-inflammatory switch and attenuates symptoms in experimental autoimmune encephalomyelitis Plos One. 7. PMID 22529957 DOI: 10.1371/journal.pone.0034933  1
2012 Yao Y, Tsirka SE. The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage Glia. 60: 908-918. PMID 22419223 DOI: 10.1002/glia.22323  1
2012 Harrington AD, Tsirka SE, Schoonen MAA. Quantification of particle-induced inflammatory stress response: A novel approach for toxicity testing of earth materials Geochemical Transactions. 13. DOI: 10.1186/1467-4866-13-4  1
2012 Yao Y, Tsirka SE. Chemokines and Their Receptors in Intracerebral Hemorrhage Translational Stroke Research. 3: 70-79. DOI: 10.1007/s12975-012-0155-z  1
2011 Mirrione MM, Tsirka SE. Neuroimaging in Animal Seizure Models with (18)FDG-PET. Epilepsy Research and Treatment. 2011: 369295. PMID 22937232 DOI: 10.1155/2011/369295  0.36
2011 Gao Z, Tsirka SE. Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis. Neurology Research International. 2011: 383087. PMID 22203900 DOI: 10.1155/2011/383087  1
2011 Bukhari N, Torres L, Robinson JK, Tsirka SE. Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system Journal of Neuroscience. 31: 14931-14943. PMID 22016526 DOI: 10.1523/JNEUROSCI.3339-11.2011  1
2011 Zhai H, Acharya S, Gravanis I, Mehmood S, Seidman RJ, Shroyer KR, Hajjar KA, Tsirka SE. Annexin A2 promotes glioma cell invasion and tumor progression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14346-60. PMID 21976520 DOI: 10.1523/JNEUROSCI.3299-11.2011  1
2011 Yao Y, Tsirka SE. Mouse MCP1 C-terminus inhibits human MCP1-induced chemotaxis and BBB compromise Journal of Neurochemistry. 118: 215-223. PMID 21615737 DOI: 10.1111/j.1471-4159.2011.07319.x  1
2011 Yao Y, Tsirka SE. Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption Journal of Cell Science. 124: 1486-1495. PMID 21486949 DOI: 10.1242/jcs.082834  1
2011 Zhai H, Heppner FL, Tsirka SE. Microglia/macrophages promote glioma progression Glia. 59: 472-485. PMID 21264953 DOI: 10.1002/glia.21117  1
2011 Gao Z, Tsirka SE. Animal models of MS reveal multiple roles of microglia in disease pathogenesis Neurology Research International. 2011. DOI: 10.1155/2011/383087  1
2010 Talos F, Abraham A, Vaseva AV, Holembowski L, Tsirka SE, Scheel A, Bode D, Dobbelstein M, Brück W, Moll UM. P73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis Cell Death and Differentiation. 17: 1816-1829. PMID 21076477 DOI: 10.1038/cdd.2010.131  1
2010 Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, Tsirka SE, Maletic-Savatic M. Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell. 7: 483-95. PMID 20887954 DOI: 10.1016/j.stem.2010.08.014  1
2010 Yao Y, Tsirka SE. The C terminus of Mouse Monocyte Chemoattractant Protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency Journal of Biological Chemistry. 285: 31509-31516. PMID 20682771 DOI: 10.1074/jbc.M110.124891  1
2010 Emmetsberger J, Mirrione MM, Zhou C, Fernandez-Monreal M, Siddiq MM, Ji K, Tsirka SE. Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4 Journal of Neuroscience. 30: 6538-6547. PMID 20463217 DOI: 10.1523/JNEUROSCI.6250-09.2010  1
2010 Mirrione MM, Konomos DK, Gravanis I, Dewey SL, Aguzzi A, Heppner FL, Tsirka SE. Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice Neurobiology of Disease. 39: 85-97. PMID 20382223 DOI: 10.1016/j.nbd.2010.04.001  1
2010 Pothakos K, Robinson JK, Gravanis I, Marsteller DA, Dewey SL, Tsirka SE. Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice Brain Research. 1326: 135-142. PMID 20156421 DOI: 10.1016/j.brainres.2009.12.095  1
2009 Wu M, Tsirka SE. Endothelial NOS-deficient mice reveal dual roles for nitric oxide during experimental autoimmune encephalomyelitis Glia. 57: 1204-1215. PMID 19170181 DOI: 10.1002/glia.20842  1
2008 Gao Z, Wang J, Thiex R, Rogove AD, Heppner FL, Tsirka SE. Microglial activation and intracerebral hemorrhage Acta Neurochirurgica, Supplementum. 51-53. PMID 19066082 DOI: 10.1007/978-3-211-09469-3-11  1
2008 Gravanis I, Tsirka SE. Tissue-type plasminogen activator as a therapeutic target in stroke Expert Opinion On Therapeutic Targets. 12: 159-170. PMID 18208365 DOI: 10.1517/14728222.12.2.159  1
2008 Nolin WB, Emmetsberger J, Bukhari N, Zhang Y, Levine JM, Tsirka SE. tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2 Glia. 56: 177-189. PMID 18000864 DOI: 10.1002/glia.20603  1
2007 Mirrione MM, Schiffer WK, Fowler JS, Alexoff DL, Dewey SL, Tsirka SE. A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. Neuroimage. 38: 34-42. PMID 17707126 DOI: 10.1016/j.neuroimage.2007.06.032  1
2007 Bhasin M, Wu M, Tsirka SE. Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis Bmc Immunology. 8. PMID 17634104 DOI: 10.1186/1471-2172-8-10  1
2007 Thiex R, Tsirka SE. Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications. Neurosurgical Focus. 22: E6. PMID 17613237  1
2007 Parathath SR, Gravanis I, Tsirka SE. Nitric oxide synthase isoforms undertake unique roles during excitotoxicity Stroke. 38: 1938-1945. PMID 17446423 DOI: 10.1161/STROKEAHA.106.478826  1
2007 Sheehan JJ, Zhou C, Gravanis I, Rogove AD, Wu YP, Bogenhagen DF, Tsirka SE. Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1738-45. PMID 17301181 DOI: 10.1523/JNEUROSCI.4987-06.2007  1
2006 Parathath SR, Parathath S, Tsirka SE. Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice Journal of Cell Science. 119: 339-349. PMID 16410551 DOI: 10.1242/jcs.02734  1
2006 Mirrione MM, Schiffer WK, Siddiq M, Dewey SL, Tsirka SE. PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy Synapse. 59: 119-121. PMID 16320304 DOI: 10.1002/syn.20216  1
2005 Wang J, Tsirka SE. Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage Neurocritical Care. 3: 77-85. PMID 16159103 DOI: 10.1385/Neurocrit.Care2005;3:77-85  1
2005 Xanthopoulos K, Paspaltsis I, Apostolidou V, Petrakis S, Siao CJ, Kalpatsanidis A, Grigoriadis N, Tsaftaris A, Tsirka SE, Sklaviadis T. Tissue plasminogen activator in brain tissues infected with transmissible spongiform encephalopathies Neurobiology of Disease. 20: 519-527. PMID 15922607 DOI: 10.1016/j.nbd.2005.04.008  1
2005 Sheehan JJ, Tsirka SE. Fibrin-modifying serine proteases thrombin, tPA, and plasmin in ischemic stroke: A review Glia. 50: 340-350. PMID 15846799 DOI: 10.1002/glia.20150  1
2005 Zhang Y, Pothakos K, Tsirka SA. Extracellular proteases: biological and behavioral roles in the mammalian central nervous system. Current Topics in Developmental Biology. 66: 161-88. PMID 15825268  0.8
2005 Wang J, Tsirka SE. Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage Brain. 128: 1622-1633. PMID 15800021 DOI: 10.1093/brain/awh489  1
2005 Zhang Y, Kanaho Y, Frohman MA, Tsirka SE. Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1797-805. PMID 15716416 DOI: 10.1523/JNEUROSCI.4850-04.2005  1
2005 Wang J, Tsirka SE. Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage Stroke. 36: 613-618. PMID 15692122 DOI: 10.1161/01.STR.0000155729.12931.8f  1
2005 Gravanis I, Tsirka SE. Tissue plasminogen activator and glial function Glia. 49: 177-183. PMID 15494978 DOI: 10.1002/glia.20115  1
2005 Zhang Y, Pothakos K, Tsirka SA(. Extracellular Proteases: Biological and Behavioral Roles in the Mammalian Central Nervous System Current Topics in Developmental Biology. 66: 161-188. DOI: 10.1016/S0070-2153(05)66005-X  0.72
2004 Thiex R, Mayfrank L, Rohde V, Gilsbach JM, Tsirka SAE. The role of endogenous versus exogenous tPA on edema formation in murine ICH Experimental Neurology. 189: 25-32. PMID 15296833 DOI: 10.1016/j.expneurol.2004.05.021  0.44
2004 Zhang Y, Huang P, Du G, Kanaho Y, Frohman MA, Tsirka SE. Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth. Glia. 46: 74-83. PMID 14999815 DOI: 10.1002/glia.10322  1
2004 Siddiq MM, Tsirka SE. Modulation of zinc toxicity by tissue plasminogen activator Molecular and Cellular Neuroscience. 25: 162-171. PMID 14962749 DOI: 10.1016/j.mcn.2003.10.007  1
2003 Wang J, Rogove AD, Tsirka AE, Tsirka SE. Protective Role of Tuftsin Fragment 1-3 in an Animal Model of Intracerebral Hemorrhage Annals of Neurology. 54: 655-664. PMID 14595655 DOI: 10.1002/ana.10750  1
2003 Siao CJ, Fernandez SR, Tsirka SE. Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury Journal of Neuroscience. 23: 3234-3242. PMID 12716930  1
2003 Indyk JA, Chen ZL, Tsirka SE, Strickland S. Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury Neuroscience. 116: 359-371. PMID 12559092 DOI: 10.1016/S0306-4522(02)00704-2  1
2002 Lu W, Bhasin M, Tsirka SE. Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis Journal of Neuroscience. 22: 10781-10789. PMID 12486171  1
2002 Rogove AD, Lu W, Tsirka SE. Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration Cell Death and Differentiation. 9: 801-806. PMID 12107823 DOI: 10.1038/sj.cdd.4401041  1
2002 Tsirka SE. Tissue plasminogen activator as a modulator of neuronal survival and function. Biochemical Society Transactions. 30: 222-225. PMID 12023855  1
2002 Siao CJ, Tsirka SE. Extracellular proteases and neuronal cell death. Cellular and Molecular Biology. 48: 151-161. PMID 11990450  1
2002 Siao CJ, Tsirka SE. Tissue Plasminogen Activator Mediates Microglial Activation via Its Finger Domain through Annexin II Journal of Neuroscience. 22: 3352-3358. PMID 11978811  1
2002 Lu W, Tsirka SE. Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator Development. 129: 2043-2050. PMID 11934869  1
2001 Mori T, Wang X, Kline AE, Siao CJ, Dixon CE, Tsirka SE, Lo EH. Reduced cortical injury and edema in tissue plasminogen activator knockout mice after brain trauma. Neuroreport. 12: 4117-20. PMID 11742249  1
2000 Wu YP, Siao CJ, Lu W, Sung TC, Frohman MA, Milev P, Bugge TH, Degen JL, Levine JM, Margolis RU, Tsirka SE. The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. The Journal of Cell Biology. 148: 1295-304. PMID 10725341 DOI: 10.1083/jcb.148.6.1295  1
1999 Rogove AD, Siao CJ, Keyt B, Strickland S, Tsirka SE. Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system Journal of Cell Science. 112: 4007-4016. PMID 10547361  1
1998 Wang YF, Tsirka SE, Strickland S, Stieg PE, Soriano SG, Lipton SA. Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nature Medicine. 4: 228-31. PMID 9461198 DOI: 10.1038/nm0298-228  1
1998 Rogove AD, Tsirka SE. Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus Current Biology. 8: 19-25. PMID 9427623  1
1997 Mecenas PE, Tsirka SE, Sallés F, Strickland S. Removal of tissue plasminogen activator does not protect against neuronal degeneration in the cerebellum of the weaver mouse Brain Research. 772: 233-238. PMID 9406977 DOI: 10.1016/S0006-8993(97)00864-0  1
1997 Colley WC, Altshuller YM, Sue-Ling CK, Copeland NG, Gilbert DJ, Jenkins NA, Branch KD, Tsirka SE, Bollag RJ, Bollag WB, Frohman MA. Cloning and expression analysis of murine phospholipase D1 Biochemical Journal. 326: 745-753. PMID 9307024  0.44
1997 Tsirka SE, Bugge TH, Degen JL, Strickland S. Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin Proceedings of the National Academy of Sciences of the United States of America. 94: 9779-9781. PMID 9275201 DOI: 10.1073/pnas.94.18.9779  1
1997 Tsirka SE. Clinical implications of the involvement of tPA in neuronal cell death Journal of Molecular Medicine. 75: 341-347. PMID 9181475 DOI: 10.1007/s001090050119  1
1997 Tsirka SE, Rogove AD, Bugge TH, Degen JL, Strickland S. An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus Journal of Neuroscience. 17: 543-552. PMID 8987777  1
1997 Tsirka SE, Chen ZI, Strickland S. A tpatplasmin proteolytic cascade promotes neuronal degeneration in the mammalian hippocampus Fibrinolysis and Proteolysis. 11: 15.  1
1997 Bugge TH, Danton MJS, Dang K, Daugherty CC, Drew A, Flick MJ, Holmbäck K, Kaol W, Kombrinck KW, Lund LR, Pyke C, Romcr J, Strickland S, Tsirka SE, Xiaoli Q, et al. Biological roles and substrates of plasmin in the mouse Faseb Journal. 11: A1444.  1
1996 Strickland S, Gualandris A, Rogove AD, Tsirka SE. Extracellular proteases in neuronal function and degeneration Cold Spring Harbor Symposia On Quantitative Biology. 61: 739-745. PMID 9246499  1
1996 Tsirka SE, Rogove AD, Strickland S. Neuronal cell death and tPA [4] Nature. 384: 123-124. PMID 8906786  1
1996 West MF, Verrotti AC, Sallés FJ, Tsirka SE, Strickland S. Isolation and characterization of two novel, cytoplasmically polyadenylated, oocyte-specific, mouse maternal RNAs Developmental Biology. 175: 132-141. PMID 8608859 DOI: 10.1006/dbio.1996.0101  1
1996 Gualandris A, Jones TE, Strickland S, Tsirka SE. Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator Journal of Neuroscience. 16: 2220-2225. PMID 8601802  1
1995 Tsirka SE, Gualandris A, Amaral DG, Strickland S. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature. 377: 340-4. PMID 7566088 DOI: 10.1038/377340a0  1
1994 Carroll PM, Tsirka SE, Richards WG, Frohman MA, Strickland S. The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in development and a seizure-enhanced response in the CNS Development. 120: 3173-3183. PMID 7720560  1
1993 Tsirka SE, Turck CW, Coffino P. Multiple active conformers of mouse ornithine decarboxylase Biochemical Journal. 293: 289-295. PMID 8328969  1
1992 Tsirka S, Coffino P. Dominant negative mutants of ornithine decarboxylase Journal of Biological Chemistry. 267: 23057-23062. PMID 1429654  1
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