Year |
Citation |
Score |
2023 |
Zhu S, Xu R, Engel AL, Wang Y, McNeel R, Hurley JB, Chao JR, Du J. Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina. The Journal of Biological Chemistry. 105275. PMID 37741457 DOI: 10.1016/j.jbc.2023.105275 |
0.327 |
|
2023 |
Zhu S, Xu R, Engel A, Wang Y, McNeel R, Hurley JB, Chao JR, Du J. Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina. Biorxiv : the Preprint Server For Biology. PMID 37131780 DOI: 10.1101/2023.04.18.537355 |
0.327 |
|
2021 |
Hurley JB. Retina Metabolism and Metabolism in the Pigmented Epithelium: A Busy Intersection. Annual Review of Vision Science. PMID 34102066 DOI: 10.1146/annurev-vision-100419-115156 |
0.321 |
|
2021 |
Ferrington DA, Kenney MC, Atilano SR, Hurley JB, Brown EE, Ash JD. Mitochondria: The Retina's Achilles' Heel in AMD. Advances in Experimental Medicine and Biology. 1256: 237-264. PMID 33848005 DOI: 10.1007/978-3-030-66014-7_10 |
0.307 |
|
2021 |
Shen W, Lee SR, Mathai AE, Zhang R, Du J, Yam MX, Pye V, Barnett NL, Rayner CL, Zhu L, Hurley JB, Seth P, Hirabayashi Y, Furuya S, Gillies MC. Effect of selectively knocking down key metabolic genes in Müller glia on photoreceptor health. Glia. PMID 33835598 DOI: 10.1002/glia.24005 |
0.308 |
|
2021 |
Sinha T, Du J, Makia MS, Hurley JB, Naash MI, Al-Ubaidi MR. Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526685 DOI: 10.1073/pnas.2018956118 |
0.343 |
|
2020 |
Giarmarco MM, Brock DC, Robbings BM, Cleghorn WM, Tsantilas KA, Kuch KC, Ge W, Rutter KM, Parker ED, Hurley JB, Brockerhoff SE. Daily mitochondrial dynamics in cone photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 33144507 DOI: 10.1073/pnas.2007827117 |
0.666 |
|
2020 |
Bisbach CM, Hutto RA, Poria D, Cleghorn WM, Abbas F, Vinberg F, Kefalov VJ, Hurley JB, Brockerhoff SE. Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca uptake in photoreceptor mitochondria. Scientific Reports. 10: 16041. PMID 32994451 DOI: 10.1038/s41598-020-72708-x |
0.666 |
|
2020 |
Bisbach CM, Hass DT, Robbings BM, Rountree AM, Sadilek M, Sweet IR, Hurley JB. Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O-Rich Pigment Epithelium. Cell Reports. 31: 107606. PMID 32375026 DOI: 10.1016/J.Celrep.2020.107606 |
0.333 |
|
2020 |
Ward R, Kaylor JJ, Cobice DF, Pepe DA, McGarrigle EM, Brockerhoff SE, Hurley JB, Travis GH, Kennedy BN. Non-photopic and photopic visual cycles differentially regulate immediate, early and late-phases of cone photoreceptor-mediated vision. The Journal of Biological Chemistry. PMID 32238432 DOI: 10.1074/jbc.RA119.011374 |
0.724 |
|
2020 |
Hurley JB, Chao JR. Retinal disease: How to use proteomics to speed up diagnosis and metabolomics to slow down degeneration. Ebiomedicine. 53: 102687. PMID 32113163 DOI: 10.1016/j.ebiom.2020.102687 |
0.343 |
|
2019 |
Hutto RA, Bisbach CM, Abbas F, Brock DC, Cleghorn WM, Parker ED, Bauer BH, Ge W, Vinberg F, Hurley JB, Brockerhoff SE. Increasing Ca in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress. Cell Death and Differentiation. PMID 31371786 DOI: 10.1038/S41418-019-0398-2 |
0.68 |
|
2019 |
Grenell A, Wang Y, Yam M, Swarup A, Dilan TL, Hauer A, Linton JD, Philp NJ, Gregor E, Zhu S, Shi Q, Murphy J, Guan T, Lohner D, Kolandaivelu S, ... ... Hurley JB, et al. Loss of MPC1 reprograms retinal metabolism to impair visual function. Proceedings of the National Academy of Sciences of the United States of America. 116: 3530-3535. PMID 30808746 DOI: 10.1073/Pnas.1812941116 |
0.454 |
|
2018 |
Zhu S, Yam M, Wang Y, Linton JD, Grenell A, Hurley JB, Du J. Impact of euthanasia, dissection and postmortem delay on metabolic profile in mouse retina and RPE/choroid. Experimental Eye Research. PMID 29864440 DOI: 10.1016/j.exer.2018.05.032 |
0.414 |
|
2018 |
Giarmarco MM, Cleghorn WM, Hurley JB, Brockerhoff SE. Preparing Fresh Retinal Slices from Adult Zebrafish for Ex Vivo Imaging Experiments. Journal of Visualized Experiments : Jove. PMID 29806828 DOI: 10.3791/56977 |
0.713 |
|
2018 |
Du J, An J, Linton JD, Wang Y, Hurley JB. How Excessive cGMP Impacts Metabolic Proteins in Retinas at the Onset of Degeneration. Advances in Experimental Medicine and Biology. 1074: 289-295. PMID 29721955 DOI: 10.1007/978-3-319-75402-4_35 |
0.455 |
|
2018 |
Rajala A, Wang Y, Brush RS, Tsantilas K, Jankowski CSR, Lindsay KJ, Linton JD, Hurley JB, Anderson RE, Rajala RVS. Pyruvate kinase M2 regulates photoreceptor structure, function, and viability. Cell Death & Disease. 9: 240. PMID 29445082 DOI: 10.1038/S41419-018-0296-4 |
0.791 |
|
2017 |
Kanow MA, Giarmarco MM, Jankowski CS, Tsantilas K, Engel AL, Du J, Linton JD, Farnsworth CC, Sloat SR, Rountree A, Sweet IR, Lindsay KJ, Parker ED, Brockerhoff SE, Sadilek M, ... ... Hurley JB, et al. Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye. Elife. 6. PMID 28901286 DOI: 10.7554/Elife.28899 |
0.807 |
|
2017 |
Hurley JB. Warburg's vision. Elife. 6. PMID 28681722 DOI: 10.7554/eLife.29217 |
0.334 |
|
2017 |
Chao JR, Knight K, Engel AL, Jankowski C, Wang Y, Manson MA, Gu H, Djukovic D, Raftery D, Hurley JB, Du J. Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side. The Journal of Biological Chemistry. 292: 12895-12905. PMID 28615447 DOI: 10.1074/Jbc.M117.788422 |
0.415 |
|
2017 |
Giarmarco MM, Cleghorn WM, Sloat SR, Hurley JB, Brockerhoff SE. Mitochondria Maintain Distinct Ca Pools in Cone Photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 2061-2072. PMID 28115482 DOI: 10.1523/Jneurosci.2689-16.2017 |
0.675 |
|
2017 |
Kanow MA, Giarmarco MM, Jankowski CS, Tsantilas K, Engel AL, Du J, Linton JD, Farnsworth CC, Sloat SR, Rountree A, Sweet IR, Lindsay KJ, Parker ED, Brockerhoff SE, Sadilek M, ... ... Hurley JB, et al. Author response: Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye Elife. DOI: 10.7554/Elife.28899.014 |
0.797 |
|
2016 |
Du J, Yanagida A, Knight K, Engel AL, Vo AH, Jankowski C, Sadilek M, Tran VT, Manson MA, Ramakrishnan A, Hurley JB, Chao JR. Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America. 113: 14710-14715. PMID 27911769 DOI: 10.1073/Pnas.1604572113 |
0.405 |
|
2016 |
Zhang L, Du J, Justus S, Hsu CW, Bonet-Ponce L, Wu WH, Tsai YT, Wu WP, Jia Y, Duong JK, Mahajan VB, Lin CS, Wang S, Hurley JB, Tsang SH. Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration. The Journal of Clinical Investigation. 126: 4659-4673. PMID 27841758 DOI: 10.1172/Jci86905 |
0.455 |
|
2016 |
Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrústegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB. Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina. The Journal of Biological Chemistry. 291: 4698-710. PMID 26677218 DOI: 10.1074/Jbc.M115.698985 |
0.782 |
|
2015 |
Du J, Linton JD, Hurley JB. Probing Metabolism in the Intact Retina Using Stable Isotope Tracers. Methods in Enzymology. 561: 149-70. PMID 26358904 DOI: 10.1016/bs.mie.2015.04.002 |
0.453 |
|
2015 |
Hurley JB, Chao JR. It's never too late to save a photoreceptor. The Journal of Clinical Investigation. 125: 3424-6. PMID 26301805 DOI: 10.1172/JCI83194 |
0.323 |
|
2015 |
Hurley JB, Lindsay KJ, Du J. Glucose, lactate, and shuttling of metabolites in vertebrate retinas. Journal of Neuroscience Research. 93: 1079-92. PMID 25801286 DOI: 10.1002/Jnr.23583 |
0.78 |
|
2014 |
Lindsay KJ, Du J, Sloat SR, Contreras L, Linton JD, Turner SJ, Sadilek M, Satrústegui J, Hurley JB. Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina. Proceedings of the National Academy of Sciences of the United States of America. 111: 15579-84. PMID 25313047 DOI: 10.1073/Pnas.1412441111 |
0.76 |
|
2014 |
Adijanto J, Du J, Moffat C, Seifert EL, Hurley JB, Philp NJ. The retinal pigment epithelium utilizes fatty acids for ketogenesis implications for metabolic coupling with the outer retina Journal of Biological Chemistry. 289: 20570-20582. PMID 24898254 DOI: 10.1074/Jbc.M114.565457 |
0.388 |
|
2014 |
Hurley JB, Chertov AO, Lindsay K, Giamarco M, Cleghorn W, Du J, Brockerhoff S. Energy metabolism in the vertebrate retina Vertebrate Photoreceptors: Functional Molecular Bases. 91-137. DOI: 10.1007/978-4-431-54880-5_5 |
0.764 |
|
2013 |
Du J, Cleghorn WM, Contreras L, Lindsay K, Rountree AM, Chertov AO, Turner SJ, Sahaboglu A, Linton J, Sadilek M, Satrústegui J, Sweet IR, Paquet-Durand F, Hurley JB. Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina. The Journal of Biological Chemistry. 288: 36129-40. PMID 24187136 DOI: 10.1074/Jbc.M113.507285 |
0.76 |
|
2013 |
Du J, Cleghorn W, Contreras L, Linton JD, Chan GC, Chertov AO, Saheki T, Govindaraju V, Sadilek M, Satrústegui J, Hurley JB. Cytosolic reducing power preserves glutamate in retina. Proceedings of the National Academy of Sciences of the United States of America. 110: 18501-6. PMID 24127593 DOI: 10.1073/Pnas.1311193110 |
0.769 |
|
2011 |
Chertov AO, Holzhausen L, Kuok IT, Couron D, Parker E, Linton JD, Sadilek M, Sweet IR, Hurley JB. Roles of glucose in photoreceptor survival. The Journal of Biological Chemistry. 286: 34700-11. PMID 21840997 DOI: 10.1074/Jbc.M111.279752 |
0.792 |
|
2011 |
Morrissey ME, Shelton S, Brockerhoff SE, Hurley JB, Kennedy BN. PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors. Bmc Developmental Biology. 11: 3. PMID 21261954 DOI: 10.1186/1471-213X-11-3 |
0.679 |
|
2010 |
Linton JD, Holzhausen LC, Babai N, Song H, Miyagishima KJ, Stearns GW, Lindsay K, Wei J, Chertov AO, Peters TA, Caffe R, Pluk H, Seeliger MW, Tanimoto N, Fong K, ... ... Hurley JB, et al. Flow of energy in the outer retina in darkness and in light. Proceedings of the National Academy of Sciences of the United States of America. 107: 8599-604. PMID 20445106 DOI: 10.1073/Pnas.1002471107 |
0.78 |
|
2010 |
Lee KA, Nawrot M, Garwin GG, Saari JC, Hurley JB. Relationships among visual cycle retinoids, rhodopsin phosphorylation, and phototransduction in mouse eyes during light and dark adaptation. Biochemistry. 49: 2454-63. PMID 20155952 DOI: 10.1021/Bi1001085 |
0.616 |
|
2009 |
Doan T, Azevedo AW, Hurley JB, Rieke F. Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11867-79. PMID 19776273 DOI: 10.1523/Jneurosci.0819-09.2009 |
0.305 |
|
2009 |
Kolandaivelu S, Huang J, Hurley JB, Ramamurthy V. AIPL1, a protein associated with childhood blindness, interacts with alpha-subunit of rod phosphodiesterase (PDE6) and is essential for its proper assembly. The Journal of Biological Chemistry. 284: 30853-61. PMID 19758987 DOI: 10.1074/Jbc.M109.036780 |
0.349 |
|
2009 |
Morgans CW, Kensel-Hammes P, Hurley JB, Burton K, Idzerda R, McKnight GS, Bajjalieh SM. Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina. Plos One. 4: e5230. PMID 19381277 DOI: 10.1371/Journal.Pone.0005230 |
0.311 |
|
2008 |
Slepak VZ, Hurley JB. Mechanism of light-induced translocation of arrestin and transducin in photoreceptors: interaction-restricted diffusion. Iubmb Life. 60: 2-9. PMID 18379987 DOI: 10.1002/Iub.7 |
0.352 |
|
2007 |
Vishnivetskiy SA, Raman D, Wei J, Kennedy MJ, Hurley JB, Gurevich VV. Regulation of arrestin binding by rhodopsin phosphorylation level. The Journal of Biological Chemistry. 282: 32075-83. PMID 17848565 DOI: 10.1074/Jbc.M706057200 |
0.545 |
|
2007 |
Rosenzweig DH, Nair KS, Wei J, Wang Q, Garwin G, Saari JC, Chen CK, Smrcka AV, Swaroop A, Lem J, Hurley JB, Slepak VZ. Subunit dissociation and diffusion determine the subcellular localization of rod and cone transducins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5484-94. PMID 17507570 DOI: 10.1523/Jneurosci.1421-07.2007 |
0.386 |
|
2007 |
Kennedy BN, Alvarez Y, Brockerhoff SE, Stearns GW, Sapetto-Rebow B, Taylor MR, Hurley JB. Identification of a zebrafish cone photoreceptor-specific promoter and genetic rescue of achromatopsia in the nof mutant. Investigative Ophthalmology & Visual Science. 48: 522-9. PMID 17251445 DOI: 10.1167/iovs.06-0975 |
0.722 |
|
2006 |
Schwartz ML, Hurley JB, Ramamurthy V. Biochemical function of the LCA linked protein, aryl hydrocarbon receptor interacting protein like-1 (AIPL1). Role of AIPL1 in retina. Advances in Experimental Medicine and Biology. 572: 89-94. PMID 17249560 DOI: 10.1007/0-387-32442-9_14 |
0.353 |
|
2006 |
Moussaif M, Rubin WW, Kerov V, Reh R, Chen D, Lem J, Chen CK, Hurley JB, Burns ME, Artemyev NO. Phototransduction in a transgenic mouse model of Nougaret night blindness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6863-72. PMID 16793893 DOI: 10.1523/Jneurosci.1322-06.2006 |
0.336 |
|
2006 |
Nathan J, Reh R, Ankoudinova I, Ankoudinova G, Chang B, Heckenlively J, Hurley JB. Scotopic and photopic visual thresholds and spatial and temporal discrimination evaluated by behavior of mice in a water maze. Photochemistry and Photobiology. 82: 1489-94. PMID 16683905 DOI: 10.1562/2006-02-27-RA-818 |
0.316 |
|
2005 |
Strissel KJ, Lishko PV, Trieu LH, Kennedy MJ, Hurley JB, Arshavsky VY. Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors. The Journal of Biological Chemistry. 280: 29250-5. PMID 15961391 DOI: 10.1074/Jbc.M501789200 |
0.588 |
|
2005 |
Nair KS, Hanson SM, Mendez A, Gurevich EV, Kennedy MJ, Shestopalov VI, Vishnivetskiy SA, Chen J, Hurley JB, Gurevich VV, Slepak VZ. Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions. Neuron. 46: 555-67. PMID 15944125 DOI: 10.1016/J.Neuron.2005.03.023 |
0.556 |
|
2005 |
Sampath AP, Strissel KJ, Elias R, Arshavsky VY, McGinnis JF, Chen J, Kawamura S, Rieke F, Hurley JB. Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. Neuron. 46: 413-20. PMID 15882641 DOI: 10.1016/J.Neuron.2005.04.006 |
0.4 |
|
2005 |
Wu AY, Zhao A, Rieke F, Hurley JB, Beavo JA. 353 CYCLIC AMP HYDROLYZING, CYCLIC-GMP INHIBITED PHOSPHODIESTERASE (PDE3B) IS HIGHLY EXPRESSED IN BOVINE AND GECKO PHOTORECEPTORS Journal of Investigative Medicine. 53: S140.2-S140. DOI: 10.2310/6650.2005.00005.352 |
0.396 |
|
2004 |
Van Epps HA, Hayashi M, Lucast L, Stearns GW, Hurley JB, De Camilli P, Brockerhoff SE. The zebrafish nrc mutant reveals a role for the polyphosphoinositide phosphatase synaptojanin 1 in cone photoreceptor ribbon anchoring. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8641-50. PMID 15470129 DOI: 10.1523/JNEUROSCI.2892-04.2004 |
0.777 |
|
2004 |
Ramamurthy V, Niemi GA, Reh TA, Hurley JB. Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase. Proceedings of the National Academy of Sciences of the United States of America. 101: 13897-902. PMID 15365178 DOI: 10.1073/Pnas.0404197101 |
0.431 |
|
2004 |
Nair KS, Hanson SM, Kennedy MJ, Hurley JB, Gurevich VV, Slepak VZ. Direct binding of visual arrestin to microtubules determines the differential subcellular localization of its splice variants in rod photoreceptors. The Journal of Biological Chemistry. 279: 41240-8. PMID 15272005 DOI: 10.1074/Jbc.M406768200 |
0.543 |
|
2004 |
Kennedy BN, Stearns GW, Smyth VA, Ramamurthy V, van Eeden F, Ankoudinova I, Raible D, Hurley JB, Brockerhoff SE. Zebrafish rx3 and mab21l2 are required during eye morphogenesis. Developmental Biology. 270: 336-49. PMID 15183718 DOI: 10.1016/J.Ydbio.2004.02.026 |
0.664 |
|
2004 |
Taylor MR, Hurley JB, Van Epps HA, Brockerhoff SE. A zebrafish model for pyruvate dehydrogenase deficiency: rescue of neurological dysfunction and embryonic lethality using a ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America. 101: 4584-9. PMID 15070761 DOI: 10.1073/pnas.0307074101 |
0.764 |
|
2004 |
Kennedy MJ, Dunn FA, Hurley JB. Visual pigment phosphorylation but not transducin translocation can contribute to light adaptation in zebrafish cones. Neuron. 41: 915-28. PMID 15046724 DOI: 10.1016/S0896-6273(04)00086-8 |
0.567 |
|
2003 |
Ramamurthy V, Roberts M, van den Akker F, Niemi G, Reh TA, Hurley JB. AIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteins. Proceedings of the National Academy of Sciences of the United States of America. 100: 12630-5. PMID 14555765 DOI: 10.1073/Pnas.2134194100 |
0.325 |
|
2003 |
Kennedy MJ, Sowa ME, Wensel TG, Hurley JB. Acceleration of key reactions as a strategy to elucidate the rate-limiting chemistry underlying phototransduction inactivation. Investigative Ophthalmology & Visual Science. 44: 1016-22. PMID 12601023 DOI: 10.1167/Iovs.02-0692 |
0.629 |
|
2003 |
Brockerhoff SE, Rieke F, Matthews HR, Taylor MR, Kennedy B, Ankoudinova I, Niemi GA, Tucker CL, Xiao M, Cilluffo MC, Fain GL, Hurley JB. Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and suppression of current in cones from the zebrafish mutant nof. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 470-80. PMID 12533607 DOI: 10.1523/Jneurosci.23-02-00470.2003 |
0.757 |
|
2002 |
Saari JC, Nawrot M, Garwin GG, Kennedy MJ, Hurley JB, Ghyselinck NB, Chambon P. Analysis of the visual cycle in cellular retinol-binding protein type I (CRBPI) knockout mice. Investigative Ophthalmology & Visual Science. 43: 1730-5. PMID 12036972 |
0.427 |
|
2002 |
Lee KA, Craven KB, Niemi GA, Hurley JB. Mass spectrometric analysis of the kinetics of in vivo rhodopsin phosphorylation. Protein Science : a Publication of the Protein Society. 11: 862-74. PMID 11910029 DOI: 10.1110/Ps.3870102 |
0.557 |
|
2002 |
Hurley JB. Shedding light on adaptation. The Journal of General Physiology. 119: 125-8. PMID 11815663 DOI: 10.1085/Jgp.119.2.125 |
0.333 |
|
2001 |
Ramulu P, Kennedy M, Xiong WH, Williams J, Cowan M, Blesh D, Yau KW, Hurley JB, Nathans J. Normal light response, photoreceptor integrity, and rhodopsin dephosphorylation in mice lacking both protein phosphatases with EF hands (PPEF-1 and PPEF-2). Molecular and Cellular Biology. 21: 8605-14. PMID 11713293 DOI: 10.1128/Mcb.21.24.8605-8614.2001 |
0.523 |
|
2001 |
La Spada AR, Fu YH, Sopher BL, Libby RT, Wang X, Li LY, Einum DD, Huang J, Possin DE, Smith AC, Martinez RA, Koszdin KL, Treuting PM, Ware CB, Hurley JB, et al. Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7. Neuron. 31: 913-27. PMID 11580893 DOI: 10.1016/S0896-6273(01)00422-6 |
0.362 |
|
2001 |
Goldberg AFX, Fales LM, Hurley JB, Khattree N. Folding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: Implications for heterogeneous molecular pathologies Journal of Biological Chemistry. 276: 42700-42706. PMID 11553636 DOI: 10.1074/jbc.M107511200 |
0.386 |
|
2001 |
Kennedy MJ, Lee KA, Niemi GA, Craven KB, Garwin GG, Saari JC, Hurley JB. Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation. Neuron. 31: 87-101. PMID 11498053 DOI: 10.1016/S0896-6273(01)00340-3 |
0.69 |
|
2001 |
Hurley JB, Chen J. Evaluation of the contributions of recoverin and GCAPs to rod photoreceptor light adaptation and recovery to the dark state Progress in Brain Research. 131: 395-405. PMID 11420958 DOI: 10.1016/S0079-6123(01)31032-4 |
0.337 |
|
2001 |
Krylov DM, Hurley JB. Identification of proximate regions in a complex of retinal guanylyl cyclase 1 and guanylyl cyclase-activating protein-1 by a novel mass spectrometry-based method. The Journal of Biological Chemistry. 276: 30648-54. PMID 11387342 DOI: 10.1074/jbc.M104121200 |
0.739 |
|
2001 |
Ramamurthy V, Tucker C, Wilkie SE, Daggett V, Hunt DM, Hurley JB. Interactions within the coiled-coil domain of RetGC-1 guanylyl cyclase are optimized for regulation rather than for high affinity. The Journal of Biological Chemistry. 276: 26218-29. PMID 11306565 DOI: 10.1074/Jbc.M010495200 |
0.382 |
|
2001 |
Saari JC, Nawrot M, Kennedy BN, Garwin GG, Hurley JB, Huang J, Possin DE, Crabb JW. Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation. Neuron. 29: 739-48. PMID 11301032 DOI: 10.1016/S0896-6273(01)00248-3 |
0.37 |
|
2001 |
Van Epps HA, Yim CM, Hurley JB, Brockerhoff SE. Investigations of photoreceptor synaptic transmission and light adaptation in the zebrafish visual mutant nrc. Investigative Ophthalmology & Visual Science. 42: 868-74. PMID 11222552 |
0.796 |
|
2001 |
Ng L, Hurley JB, Dierks B, Srinivas M, Saltó C, Vennström B, Reh TA, Forrest D. A thyroid hormone receptor that is required for the development of green cone photoreceptors. Nature Genetics. 27: 94-8. PMID 11138006 DOI: 10.1038/83829 |
0.373 |
|
2000 |
Wilkie SE, Newbold RJ, Deery E, Walker CE, Stinton I, Ramamurthy V, Hurley JB, Bhattacharya SS, Warren MJ, Hunt DM. Functional characterization of missense mutations at codon 838 in retinal guanylate cyclase correlates with disease severity in patients with autosomal dominant cone-rod dystrophy. Human Molecular Genetics. 9: 3065-73. PMID 11115851 DOI: 10.1093/Hmg/9.20.3065 |
0.344 |
|
2000 |
Taylor MR, Van Epps HA, Kennedy MJ, Saari JC, Hurley JB, Brockerhoff SE. Biochemical analysis of phototransduction and visual cycle in zebrafish larvae. Methods in Enzymology. 316: 536-57. PMID 10800700 DOI: 10.1016/S0076-6879(00)16748-5 |
0.78 |
|
2000 |
Hurley JB, Dizhoor AM. Heterologous expression and assays for photoreceptor guanylyl cyclases and guanylyl cyclase activating proteins Methods in Enzymology. 315: 708-717. PMID 10736735 DOI: 10.1016/S0076-6879(00)15876-8 |
0.307 |
|
1999 |
Faurobert E, Scotti A, Hurley JB, Chabre M. RET-RGS, a retina-specific regulator of G-protein signaling, is located in synaptic regions of the rat retina Neuroscience Letters. 269: 41-44. PMID 10821640 DOI: 10.1016/S0304-3940(99)00423-1 |
0.396 |
|
1999 |
Dizhoor AM, Hurley JB. Regulation of photoreceptor membrane guanylyl cyclases by guanylyl cyclase activator proteins Methods: a Companion to Methods in Enzymology. 19: 521-531. PMID 10581151 DOI: 10.1006/meth.1999.0894 |
0.379 |
|
1999 |
Tucker CL, Woodcock SC, Kelsell RE, Ramamurthy V, Hunt PM, Hurley JB. Biochemical analysis of a dimerization domain mutation in RetGC-1 associated with dominant cone-rod dystrophy Proceedings of the National Academy of Sciences of the United States of America. 96: 9039-9044. PMID 10430891 DOI: 10.1073/Pnas.96.16.9039 |
0.376 |
|
1999 |
Krylov DM, Niemi GA, Dizhoor AM, Hurley JB. Mapping sites in guanylyl cyclase activating protein-1 required for regulation of photoreceptor membrane guanylyl cyclases. The Journal of Biological Chemistry. 274: 10833-9. PMID 10196159 DOI: 10.1074/Jbc.274.16.10833 |
0.749 |
|
1999 |
Olshevskaya EV, Boikov S, Ermilov A, Krylov D, Hurley JB, Dizhoor AM. Mapping functional domains of the guanylate cyclase regulator protein, GCAP-2 Journal of Biological Chemistry. 274: 10823-10832. PMID 10196158 DOI: 10.1074/Jbc.274.16.10823 |
0.748 |
|
1999 |
Chen CK, Burns ME, Spencer M, Niemi GA, Chen J, Hurley JB, Baylor DA, Simon MI. Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 3718-22. PMID 10097103 DOI: 10.1073/Pnas.96.7.3718 |
0.559 |
|
1998 |
Hughes RE, Brzovic PS, Dizhoor AM, Klevit RE, Hurley JB. Ca2+-dependent conformational changes in bovine GCAP-2 Protein Science. 7: 2675-2680. PMID 9865963 DOI: 10.1002/Pro.5560071222 |
0.3 |
|
1998 |
Laura RP, Hurley JB. The kinase homology domain of retinal guanylyl cyclases 1 and 2 specifies the affinity and cooperativity of interaction with guanylyl cyclase activating protein-2 Biochemistry. 37: 11264-11271. PMID 9698373 DOI: 10.1021/bi9809674 |
0.321 |
|
1998 |
Hurley JB, Spencer M, Niemi GA. Rhodopsin phosphorylation and its role in photoreceptor function Vision Research. 38: 1341-1352. PMID 9667002 DOI: 10.1016/S0042-6989(97)00459-8 |
0.323 |
|
1998 |
Brockerhoff SE, Dowling JE, Hurley JB. Zebrafish retinal mutants. Vision Research. 38: 1335-9. PMID 9667001 DOI: 10.1016/S0042-6989(97)00227-7 |
0.712 |
|
1998 |
Satpaev DK, Chen CK, Scotti A, Simon MI, Hurley JB, Slepak VZ. Autophosphorylation and ADP regulate the Ca2+-dependent interaction of recoverin with rhodopsin kinase. Biochemistry. 37: 10256-62. PMID 9665733 DOI: 10.1021/Bi9804986 |
0.506 |
|
1997 |
Tucker CL, Laura RP, Hurley JB. Domain-specific stabilization of photoreceptor membrane guanylyl cyclase by adenine nucleotides and guanylyl cyclase activating proteins (GCAPS) Biochemistry. 36: 11995-12000. PMID 9305994 DOI: 10.1021/bi971212k |
0.349 |
|
1997 |
Rim J, Faurobert E, Hurley JB, Oprian DD. In vitro assay for trans-phosphorylation of rhodopsin by rhodopsin kinase. Biochemistry. 36: 7064-70. PMID 9188705 DOI: 10.1021/Bi970470E |
0.324 |
|
1997 |
Olshevskaya EV, Hughes RE, Hurley JB, Dizhoor AM. Calcium binding, but not a calcium-myristoyl switch, controls the ability of guanylyl cyclase-activating protein GCAP-2 to regulate photoreceptor guanylyl cyclase Journal of Biological Chemistry. 272: 14327-14333. PMID 9162068 DOI: 10.1074/Jbc.272.22.14327 |
0.339 |
|
1997 |
Brockerhoff SE, Hurley JB, Niemi GA, Dowling JE. A new form of inherited red-blindness identified in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4236-42. PMID 9151740 DOI: 10.1523/Jneurosci.17-11-04236.1997 |
0.707 |
|
1997 |
Faurobert E, Hurley JB. The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro Proceedings of the National Academy of Sciences of the United States of America. 94: 2945-2950. PMID 9096326 DOI: 10.1073/pnas.94.7.2945 |
0.316 |
|
1996 |
Laura RP, Dizhoor AM, Hurley JB. The membrane guanylyl cyclase, retinal guanylyl cyclase-1, is activated through its intracellular domain Journal of Biological Chemistry. 271: 11646-11651. PMID 8662612 DOI: 10.1074/jbc.271.20.11646 |
0.379 |
|
1996 |
Faurobert E, Chen CK, Hurley JB, Teng DHF. Drosophila neurocalcin, a fatty acylated, Ca2+-binding protein that associates with membranes and inhibits in Vitro phosphorylation of bovine rhodopsin Journal of Biological Chemistry. 271: 10256-10262. PMID 8626592 DOI: 10.1074/Jbc.271.17.10256 |
0.313 |
|
1996 |
Brockerhoff SE, Hurley JB, Dowling JE. Retinal mutants in zebrafish identified by behavioral screening Investigative Ophthalmology and Visual Science. 37: S677. |
0.655 |
|
1995 |
Lowe DG, Dizhoor AM, Liu K, Gu Q, Spencer M, Laura R, Lu L, Hurley JB. Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2 Proceedings of the National Academy of Sciences of the United States of America. 92: 5535-5539. PMID 7777544 DOI: 10.1073/pnas.92.12.5535 |
0.38 |
|
1995 |
Deer JLR, Hurley JB, Yarfitz SL. G protein control of Drosophila photoreceptor phospholipase C Journal of Biological Chemistry. 270: 12623-12628. PMID 7759511 DOI: 10.1074/jbc.270.21.12623 |
0.349 |
|
1995 |
Chen CK, Inglese J, Lefkowitz RJ, Hurley JB. Ca(2+)-dependent interaction of recoverin with rhodopsin kinase. The Journal of Biological Chemistry. 270: 18060-6. PMID 7629115 DOI: 10.1074/JBC.270.30.18060 |
0.336 |
|
1995 |
Dizhoor AM, Olshevskaya EV, Henzel WJ, Wong SC, Stults JT, Ankoudinova I, Hurley JB. Cloning, sequencing, and expression of a 24-kDa Ca2+-binding protein activating photoreceptor guanylyl cyclase Journal of Biological Chemistry. 270: 25200-25206. PMID 7559656 DOI: 10.1074/Jbc.270.42.25200 |
0.337 |
|
1995 |
Brockerhoff SE, Hurley JB, Janssen-Bienhold U, Neuhauss SC, Driever W, Dowling JE. A behavioral screen for isolating zebrafish mutants with visual system defects. Proceedings of the National Academy of Sciences of the United States of America. 92: 10545-9. PMID 7479837 DOI: 10.1073/Pnas.92.23.10545 |
0.69 |
|
1995 |
Hurley JB. Recoverin and Ca2+ in vertebrate phototransduction Behavioral and Brain Sciences. 18: 425-428. DOI: 10.1017/S0140525X00039182 |
0.41 |
|
1994 |
Dizhoor AM, Lowe DG, Olshevskaya EV, Laura RP, Hurley JB. The human photoreceptor membrane guanylyl cyclase, RetGC, is present in outer segments and is regulated by calcium and a soluble activator. Neuron. 12: 1345-52. PMID 7912093 DOI: 10.1016/0896-6273(94)90449-9 |
0.382 |
|
1994 |
Hurley JB. Termination of photoreceptor responses Current Opinion in Neurobiology. 4: 481-487. PMID 7812135 DOI: 10.1016/0959-4388(94)90047-7 |
0.392 |
|
1993 |
Fitch CL, de Sousa SM, O'Day PM, Neubert TA, Plantilla CM, Spencer M, Yarfitz S, Apte D, Hurley JB. Pertussis toxin expression in Drosophila alters the visual response and blocks eating behaviour. Cellular Signalling. 5: 187-207. PMID 8499226 DOI: 10.1016/0898-6568(93)90070-3 |
0.3 |
|
1993 |
Hamilton SE, Prusti RK, Bentley JK, Beavo JA, Hurley JB. Affinities of bovine photoreceptor cGMP phosphodiesterases for rod and cone inhibitory subunits. Febs Letters. 318: 157-61. PMID 8382627 DOI: 10.1016/0014-5793(93)80012-J |
0.386 |
|
1993 |
Hurley JB, Dizhoor AM, Ray S, Stryer L. Recoverin's role: conclusion withdrawn. Science (New York, N.Y.). 260: 740. PMID 8097896 DOI: 10.1126/Science.8097896 |
0.53 |
|
1992 |
Dizhoor AM, Ericsson LH, Johnson RS, Kumar S, Olshevskaya E, Zozulya S, Neubert TA, Stryer L, Hurley JB, Walsh KA. The NH2 terminus of retinal recoverin is acylated by a small family of fatty acids. The Journal of Biological Chemistry. 267: 16033-6. PMID 1386601 |
0.602 |
|
1992 |
Ray S, Zozulya S, Niemi GA, Flaherty KM, Brolley D, Dizhoor AM, McKay DB, Hurley J, Stryer L. Cloning, expression, and crystallization of recoverin, a calcium sensor in vision. Proceedings of the National Academy of Sciences of the United States of America. 89: 5705-9. PMID 1385864 DOI: 10.1073/Pnas.89.13.5705 |
0.582 |
|
1991 |
Curcio CA, Allen KA, Sloan KR, Lerea CL, Hurley JB, Klock IB, Milam AH. Distribution and morphology of human cone photoreceptors stained with anti-blue opsin. The Journal of Comparative Neurology. 312: 610-24. PMID 1722224 DOI: 10.1002/cne.903120411 |
0.38 |
|
1991 |
Dizhoor AM, Ray S, Kumar S, Niemi G, Spencer M, Brolley D, Walsh KA, Philipov PP, Hurley JB, Stryer L. Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase. Science (New York, N.Y.). 251: 915-8. PMID 1672047 DOI: 10.1126/Science.1672047 |
0.583 |
|
1989 |
Lerea CL, Bunt-Milam AH, Hurley JB. α transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina Neuron. 3: 367-376. PMID 2534964 DOI: 10.1016/0896-6273(89)90261-4 |
0.33 |
|
1988 |
Hopkins RS, Stamnes MA, Simon MI, Hurley JB. Cholera toxin and pertussis toxin substrates and endogenous ADP-ribosyltransferase activity in Drosophila melanogaster. Biochimica Et Biophysica Acta. 970: 355-62. PMID 3135838 DOI: 10.1016/0167-4889(88)90135-8 |
0.498 |
|
1986 |
Lerea CL, Somers DE, Hurley JB, Klock IB, Bunt-Milam AH. Identification of specific transducin alpha subunits in retinal rod and cone photoreceptors. Science (New York, N.Y.). 234: 77-80. PMID 3529395 DOI: 10.1126/science.3529395 |
0.372 |
|
1986 |
Fong HKW, Hurley JB, Hopkins RS, Miake-Lye R, Johnson MS, Doolittle RF, Simon MI. Repetitive segmental structure of the transducin β subunit: Homology with the CDC4 gene and identification of related mRNAs Proceedings of the National Academy of Sciences of the United States of America. 83: 2162-2166. PMID 3083416 DOI: 10.1073/Pnas.83.7.2162 |
0.438 |
|
1985 |
Lochrie MA, Hurley JB, Simon MI. Sequence of the alpha subunit of photoreceptor G protein: homologies between transducin, ras, and elongation factors. Science (New York, N.Y.). 228: 96-9. PMID 3856323 DOI: 10.1126/Science.3856323 |
0.43 |
|
1984 |
Hurley JB, Fong HK, Teplow DB, Dreyer WJ, Simon MI. Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin. Proceedings of the National Academy of Sciences of the United States of America. 81: 6948-52. PMID 6438626 DOI: 10.1073/Pnas.81.22.6948 |
0.435 |
|
1984 |
Hurley JB, Simon MI, Teplow DB, Robishaw JD, Gilman AG. Homologies between signal transducing G proteins and ras gene products. Science (New York, N.Y.). 226: 860-2. PMID 6436980 DOI: 10.1126/Science.6436980 |
0.439 |
|
1983 |
Stryer L, Hurley JB, Fung BK. Transducin and the cyclic GMP phosphodiesterase of retinal rod outer segments. Methods in Enzymology. 96: 617-27. PMID 6318024 DOI: 10.1016/S0076-6879(83)96054-8 |
0.616 |
|
1982 |
Hurley JB, Stryer L. Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments. The Journal of Biological Chemistry. 257: 11094-9. PMID 6286681 |
0.542 |
|
1982 |
Hurley JB. [73] Isolation and assay of a phosphodiesterase inhibitor from retinal rod outer segments Methods in Enzymology. 81: 542-547. PMID 6285128 DOI: 10.1016/S0076-6879(82)81075-6 |
0.325 |
|
1982 |
Abood ME, Hurley JB, Pappone MC, Bourne HR, Stryer L. Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin. The Journal of Biological Chemistry. 257: 10540-3. PMID 6125514 |
0.554 |
|
1981 |
Fung BK, Hurley JB, Stryer L. Flow of information in the light-triggered cyclic nucleotide cascade of vision. Proceedings of the National Academy of Sciences of the United States of America. 78: 152-6. PMID 6264430 DOI: 10.1073/Pnas.78.1.152 |
0.581 |
|
1981 |
Hurley JB, Barry B, Ebrey TG. Isolation of an inhibitory protein for the cyclic guanosine 3′,5′-monophosphate phosphodiesterase of bovine rod outer segments Bba - General Subjects. 675: 359-365. PMID 6115678 DOI: 10.1016/0304-4165(81)90026-X |
0.505 |
|
1981 |
Ebrey TG, Kilbride P, Hurley JB, Calhoon R, Tsuda M. Chapter 7 Light Control of Cyclic-Nucleotide Concentration in the Retina Current Topics in Membranes and Transport. 15: 121-132. DOI: 10.1016/S0070-2161(08)60498-0 |
0.603 |
|
1981 |
Stryer L, Hurley JB, Fung BKK. Chapter 5 First Stage of Amplification in the Cyclic-Nucleotide Cascade of Vision Current Topics in Membranes and Transport. 15: 93-108. DOI: 10.1016/S0070-2161(08)60496-7 |
0.608 |
|
1981 |
Stryer L, Hurley JB, Fung BKK. Transducin: an amplifier protein in vision Trends in Biochemical Sciences. 6: 245-247. DOI: 10.1016/0968-0004(81)90089-X |
0.611 |
|
1978 |
Hurley JB, Ebrey TG. Energy transfer in the purple membrane of Halobacterium halobium Biophysical Journal. 22: 49-66. PMID 638226 DOI: 10.1016/S0006-3495(78)85470-8 |
0.444 |
|
1978 |
Hurley JB, Becher B, Ebrey TG. More evidence that light isomerises the chromophore of purple membrane protein Nature. 272: 87-88. PMID 628440 DOI: 10.1038/272087A0 |
0.526 |
|
1977 |
Hurley JB, Ebrey TG, Honig B, Ottolenghi M. Temperature and wavelength effects on the photochemistry of rhodopsin, isorhodopsin, bacteriorhodopsin and their photoproducts Nature. 270: 540-542. PMID 593379 DOI: 10.1038/270540A0 |
0.512 |
|
1977 |
Rosenfeld T, Honig B, Ottolenghi M, Hurley J, Ebrey TG. Cis-Trans Isomerization in the Photochemistry of Vision Pure and Applied Chemistry. 49: 341-351. DOI: 10.1351/Pac197749030341 |
0.493 |
|
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