Kenneth P. Mackie - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cannabinoid receptors and signaling

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Year Citation  Score
2015 Lu HC, Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry. PMID 26698193 DOI: 10.1016/j.biopsych.2015.07.028  0.84
2015 Hu SS, Mackie K. Distribution of the Endocannabinoid System in the Central Nervous System. Handbook of Experimental Pharmacology. 231: 59-93. PMID 26408158 DOI: 10.1007/978-3-319-20825-1_3  0.84
2015 Ballinger MD, Saito A, Abazyan B, Taniguchi Y, Huang CH, Ito K, Zhu X, Segal H, Jaaro-Peled H, Sawa A, Mackie K, Pletnikov MV, Kamiya A. Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory. Neurobiology of Disease. PMID 26093170 DOI: 10.1016/j.nbd.2015.06.006  0.84
2015 Marcus DJ, Zee M, Hughes A, Yuill MB, Hohmann AG, Mackie K, Guindon J, Morgan DJ. Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase. Molecular Pain. 11: 34. PMID 26065412 DOI: 10.1186/s12990-015-0031-4  0.84
2015 Bashashati M, Nasser Y, Keenan CM, Ho W, Piscitelli F, Nalli M, Mackie K, Storr MA, Di Marzo V, Sharkey KA. Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. British Journal of Pharmacology. 172: 3099-111. PMID 25684407 DOI: 10.1111/bph.13114  0.84
2015 Mukhopadhyay B, Schuebel K, Mukhopadhyay P, Cinar R, Godlewski G, Xiong K, Mackie K, Lizak M, Yuan Q, Goldman D, Kunos G. Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology (Baltimore, Md.). 61: 1615-26. PMID 25580584 DOI: 10.1002/hep.27686  0.84
2015 Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner. British Journal of Pharmacology. 172: 2406-18. PMID 25572435 DOI: 10.1111/bph.13069  0.84
2015 Deng L, Guindon J, Cornett BL, Makriyannis A, Mackie K, Hohmann AG. Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal. Biological Psychiatry. 77: 475-87. PMID 24853387 DOI: 10.1016/j.biopsych.2014.04.009  0.84
2015 Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model Pharmacological Research. 99: 370-376. DOI: 10.1016/j.phrs.2015.07.017  0.84
2015 Reyes BAS, Heldt NA, Mackie K, Van Bockstaele EJ. Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons Neuroscience. 303: 323-337. DOI: 10.1016/j.neuroscience.2015.07.009  0.84
2014 Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T. Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature Reviews. Neuroscience. 15: 786-801. PMID 25409697 DOI: 10.1038/nrn3846  0.84
2014 Melis M, Sagheddu C, De Felice M, Casti A, Madeddu C, Spiga S, Muntoni AL, Mackie K, Marsicano G, Colombo G, Castelli MP, Pistis M. Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12716-24. PMID 25232109 DOI: 10.1523/JNEUROSCI.1844-14.2014  0.84
2014 Cathel AM, Reyes BA, Wang Q, Palma J, Mackie K, Van Bockstaele EJ, Kirby LG. Cannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortex. The European Journal of Neuroscience. 40: 3202-14. PMID 25131562 DOI: 10.1111/ejn.12690  0.84
2014 Dhopeshwarkar A, Mackie K. CB2cannabinoid receptors as a therapeutic target-what does the future hold? Molecular Pharmacology. 86: 430-437. PMID 25106425 DOI: 10.1124/mol.114.094649  0.84
2014 Flores-Otero J, Ahn KH, Delgado-Peraza F, Mackie K, Kendall DA, Yudowski GA. Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature Communications. 5: 4589. PMID 25081814 DOI: 10.1038/ncomms5589  0.84
2014 Wu CS, Morgan D, Jew CP, Haskins C, Andrews MJ, Leishman E, Spencer CM, Czyzyk T, Bradshaw H, Mackie K, Lu HC. Long-term consequences of perinatal fatty acid amino hydrolase inhibition. British Journal of Pharmacology. 171: 1420-34. PMID 24730060 DOI: 10.1111/bph.12500  0.84
2014 Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K. Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5152-63. PMID 24719095 DOI: 10.1523/JNEUROSCI.3445-12.2014  0.84
2014 Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S. Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron. 81: 1111-25. PMID 24607231 DOI: 10.1016/j.neuron.2014.01.012  0.84
2014 O'Donnell BF, Mackie K. The mismatch negativity: a translational probe of auditory processing in cannabis users. Biological Psychiatry. 75: 428-9. PMID 24560430 DOI: 10.1016/j.biopsych.2014.01.015  0.84
2014 Hernández-Castellanos JM, Vivas O, Garduño J, De la Cruz L, Arenas I, Elías-Viñas D, Mackie K, García DE. Gβ₂ mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons. Biochemical and Biophysical Research Communications. 445: 250-4. PMID 24513289 DOI: 10.1016/j.bbrc.2014.01.192  0.84
2014 Lovelace JW, Vieira PA, Corches A, Mackie K, Korzus E. Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1685-93. PMID 24457285 DOI: 10.1038/npp.2014.15  0.84
2014 Murataeva N, Straiker A, Mackie K. Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. British Journal of Pharmacology. 171: 1379-91. PMID 24102242 DOI: 10.1111/bph.12411  0.84
2014 Lutomski CA, El-Baba TJ, Inutan ED, Manly CD, Wager-Miller J, Mackie K, Trimpin S. Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet Analytical Chemistry. 86: 6208-6213. DOI: 10.1021/ac501788p  0.84
2013 Cluny NL, Baraboi ED, Mackie K, Burdyga G, Richard D, Dockray GJ, Sharkey KA. High fat diet and body weight have different effects on cannabinoid CB(1) receptor expression in rat nodose ganglia. Autonomic Neuroscience : Basic & Clinical. 179: 122-30. PMID 24145047 DOI: 10.1016/j.autneu.2013.09.015  0.84
2013 Petrov RR, Knight L, Chen SR, Wager-Miller J, McDaniel SW, Diaz F, Barth F, Pan HL, Mackie K, Cavasotto CN, Diaz P. Mastering tricyclic ring systems for desirable functional cannabinoid activity. European Journal of Medicinal Chemistry. 69: 881-907. PMID 24125850 DOI: 10.1016/j.ejmech.2013.09.038  0.84
2013 Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A. CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. The Journal of Biological Chemistry. 288: 32685-99. PMID 24089517 DOI: 10.1074/jbc.M113.478354  0.84
2013 Chen DH, Naydenov A, Blankman JL, Mefford HC, Davis M, Sul Y, Barloon AS, Bonkowski E, Wolff J, Matsushita M, Smith C, Cravatt BF, Mackie K, Raskind WH, Stella N, et al. Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects. Human Mutation. 34: 1672-8. PMID 24027063 DOI: 10.1002/humu.22437  0.84
2013 Garzón M, Duffy AM, Chan J, Lynch MK, Mackie K, Pickel VM. Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area. Neuroscience. 252: 126-43. PMID 23954803 DOI: 10.1016/j.neuroscience.2013.08.008  0.84
2013 Jain T, Wager-Miller J, Mackie K, Straiker A. Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Molecular Pharmacology. 84: 296-302. PMID 23748223 DOI: 10.1124/mol.113.085217  0.84
2013 Cristino L, Busetto G, Imperatore R, Ferrandino I, Palomba L, Silvestri C, Petrosino S, Orlando P, Bentivoglio M, Mackie K, Di Marzo V. Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: E2229-38. PMID 23630288 DOI: 10.1073/pnas.1219485110  0.84
2013 Li K, Fichna J, Schicho R, Saur D, Bashashati M, Mackie K, Li Y, Zimmer A, Göke B, Sharkey KA, Storr M. A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology. 71: 255-63. PMID 23603203 DOI: 10.1016/j.neuropharm.2013.03.029  0.84
2013 Straiker A, Min KT, Mackie K. Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons. Neurobiology of Disease. 56: 1-5. PMID 23578490 DOI: 10.1016/j.nbd.2013.04.002  0.84
2013 Wu CS, Chen H, Sun H, Zhu J, Jew CP, Wager-Miller J, Straiker A, Spencer C, Bradshaw H, Mackie K, Lu HC. GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. Plos One. 8: e60314. PMID 23565223 DOI: 10.1371/journal.pone.0060314  0.84
2013 Cottone E, Pomatto V, Cerri F, Campantico E, Mackie K, Delpero M, Guastalla A, Dati C, Bovolin P, Franzoni MF. Cannabinoid receptors are widely expressed in goldfish: Molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs Fish Physiology and Biochemistry. 39: 1287-1296. PMID 23504102 DOI: 10.1007/s10695-013-9783-9  0.84
2013 Shonesy BC, Wang X, Rose KL, Ramikie TS, Cavener VS, Rentz T, Baucum AJ, Jalan-Sakrikar N, Mackie K, Winder DG, Patel S, Colbran RJ. CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling. Nature Neuroscience. 16: 456-63. PMID 23502535 DOI: 10.1038/nn.3353  0.84
2013 Fitzgerald ML, Mackie K, Pickel VM. The impact of adolescent social isolation on dopamine D2 and cannabinoid CB1 receptors in the adult rat prefrontal cortex. Neuroscience. 235: 40-50. PMID 23333674 DOI: 10.1016/j.neuroscience.2013.01.021  0.84
2013 Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 1935-40. PMID 23319656 DOI: 10.1073/pnas.1212563110  0.84
2013 Horne EA, Coy J, Swinney K, Fung S, Cherry AE, Marrs WR, Naydenov AV, Lin YH, Sun X, Keene CD, Grouzmann E, Muchowski P, Bates GP, Mackie K, Stella N. Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European Journal of Neuroscience. 37: 429-40. PMID 23167744 DOI: 10.1111/ejn.12045  0.84
2013 Veress G, Meszar Z, Muszil D, Avelino A, Matesz K, Mackie K, Nagy I. Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons. Brain Structure & Function. 218: 733-50. PMID 22618437 DOI: 10.1007/s00429-012-0425-2  0.84
2013 Inutan ED, Wager-Miller J, Narayan SB, Mackie K, Trimpin S. The potential for clinical applications using a new ionization method combined with ion mobility spectrometry-mass spectrometry International Journal For Ion Mobility Spectrometry. 16: 145-159. DOI: 10.1007/s12127-013-0131-7  0.84
2013 Mackie K. Endocannabinoid-mediated synaptic plasticity Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders. 11-24. DOI: 10.1007/978-1-4614-7940-6_2  0.84
2012 Péterfi Z, Urbán GM, Papp OI, Németh B, Monyer H, Szabó G, Erdélyi F, Mackie K, Freund TF, Hájos N, Katona I. Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14448-63. PMID 23055515 DOI: 10.1523/JNEUROSCI.1676-12.2012  0.84
2012 Hu H, Ho W, Mackie K, Pittman QJ, Sharkey KA. Brain CB₁ receptor expression following lipopolysaccharide-induced inflammation. Neuroscience. 227: 211-22. PMID 23041513 DOI: 10.1016/j.neuroscience.2012.09.067  0.84
2012 Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature Communications. 3: 1080. PMID 23011134 DOI: 10.1038/ncomms2045  0.84
2012 Inutan ED, Wager-Miller J, MacKie K, Trimpin S. Laserspray ionization imaging of multiply charged ions using a commercial vacuum MALDI ion source Analytical Chemistry. 84: 9079-9084. PMID 23009673 DOI: 10.1021/ac301665h  0.84
2012 Murataeva N, Mackie K, Straiker A. The CB2-preferring agonist JWH015 also potently and efficaciously activates CB1 in autaptic hippocampal neurons. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 66: 437-42. PMID 22921769 DOI: 10.1016/j.phrs.2012.08.002  0.84
2012 Pickel VM, Shobin ET, Lane DA, Mackie K. Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals. Neuroscience. 227: 10-21. PMID 22863674 DOI: 10.1016/j.neuroscience.2012.07.050  0.84
2012 Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9457-68. PMID 22787031 DOI: 10.1523/JNEUROSCI.0013-12.2012  0.84
2012 Ferreira SG, Teixeira FM, Garção P, Agostinho P, Ledent C, Cortes L, MacKie K, Köfalvi A. Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences Neurochemistry International. 61: 219-226. PMID 22609378 DOI: 10.1016/j.neuint.2012.05.009  0.84
2012 Fitzgerald ML, Chan J, Mackie K, Lupica CR, Pickel VM. Altered dendritic distribution of dopamine D2 receptors and reduction in mitochondrial number in parvalbumin-containing interneurons in the medial prefrontal cortex of cannabinoid-1 (CB1) receptor knockout mice. The Journal of Comparative Neurology. 520: 4013-31. PMID 22592925 DOI: 10.1002/cne.23141  0.84
2012 Atwood BK, Straiker A, Mackie K. CBâ‚‚ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons. Neuropharmacology. 63: 514-23. PMID 22579668 DOI: 10.1016/j.neuropharm.2012.04.024  0.84
2012 Hegyi Z, Holló K, Kis G, Mackie K, Antal M. Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. Glia. 60: 1316-29. PMID 22573306 DOI: 10.1002/glia.22351  0.84
2012 Pacher P, Mackie K. Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration Journal of Molecular Medicine. 90: 347-351. PMID 22371074 DOI: 10.1007/s00109-012-0884-1  0.84
2012 Rajesh M, Bátkai S, Kechrid M, Mukhopadhyay P, Lee WS, Horváth B, Holovac E, Cinar R, Liaudet L, Mackie K, Haskó G, Pacher P. Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. Diabetes. 61: 716-27. PMID 22315315 DOI: 10.2337/db11-0477  0.84
2012 Richards AL, Lietz CB, Wager-Miller J, Mackie K, Trimpin S. Localization and imaging of gangliosides in mouse brain tissue sections by laserspray ionization inlet Journal of Lipid Research. 53: 1390-1398. PMID 22262808 DOI: 10.1194/jlr.D019711  0.84
2012 Hons IM, Storr MA, Mackie K, Lutz B, Pittman QJ, Mawe GM, Sharkey KA. Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: e113-24. PMID 22235973 DOI: 10.1111/j.1365-2982.2011.01860.x  0.84
2012 Keimpema E, Straiker A, Mackie K, Harkany T, Hjerling-Leffler J. Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. The Journal of Physiology. 590: 703-14. PMID 22219340 DOI: 10.1113/jphysiol.2011.224386  0.84
2012 Atwood BK, Straiker A, Mackie K. CBâ‚‚: therapeutic target-in-waiting. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 16-20. PMID 22197668 DOI: 10.1016/j.pnpbp.2011.12.001  0.84
2012 Lane DA, Chan J, Fitzgerald ML, Kearn CS, Mackie K, Pickel VM. Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology. 221: 101-13. PMID 22160162 DOI: 10.1007/s00213-011-2553-4  0.84
2012 Atwood BK, Wager-Miller J, Haskins C, Straiker A, Mackie K. Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands. Molecular Pharmacology. 81: 250-63. PMID 22064678 DOI: 10.1124/mol.111.074013  0.84
2012 Straiker A, Wager-Miller J, Hutchens J, Mackie K. Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2660-71. PMID 22014238 DOI: 10.1111/j.1476-5381.2011.01744.x  0.84
2012 Straiker A, Wager-Miller J, Mackie K. The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2652-9. PMID 22014214 DOI: 10.1111/j.1476-5381.2011.01743.x  0.84
2012 López-Gallardo M, López-Rodríguez AB, Llorente-Berzal Á, Rotllant D, Mackie K, Armario A, Nadal R, Viveros MP. Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion. Neuroscience. 204: 90-103. PMID 22001306 DOI: 10.1016/j.neuroscience.2011.09.063  0.84
2012 Bashashati M, Storr MA, Nikas SP, Wood JT, Godlewski G, Liu J, Ho W, Keenan CM, Zhang H, Alapafuja SO, Cravatt BF, Lutz B, Mackie K, Kunos G, Patel KD, et al. Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. British Journal of Pharmacology. 165: 1556-71. PMID 21883147 DOI: 10.1111/j.1476-5381.2011.01644.x  0.84
2012 Morgan DJ, Muller CH, Murataeva NA, Davis BJ, Mackie K. Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity. British Journal of Pharmacology. 165: 2575-83. PMID 21615727 DOI: 10.1111/j.1476-5381.2011.01506.x  0.84
2011 Ho YC, Lee HJ, Tung LW, Liao YY, Fu SY, Teng SF, Liao HT, Mackie K, Chiou LC. Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14600-10. PMID 21994376 DOI: 10.1523/JNEUROSCI.2671-11.2011  0.84
2011 Duffy AM, Fitzgerald ML, Chan J, Robinson DC, Milner TA, Mackie K, Pickel VM. Acetylcholine α7 nicotinic and dopamine D2 receptors are targeted to many of the same postsynaptic dendrites and astrocytes in the rodent prefrontal cortex. Synapse (New York, N.Y.). 65: 1350-67. PMID 21858872 DOI: 10.1002/syn.20977  0.84
2011 Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ. Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10506-15. PMID 21775596 DOI: 10.1523/JNEUROSCI.0496-11.2011  0.84
2011 Keimpema E, Mackie K, Harkany T. Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in Pharmacological Sciences. 32: 551-61. PMID 21757242 DOI: 10.1016/j.tips.2011.05.004  0.84
2011 Schicho R, Bashashati M, Bawa M, McHugh D, Saur D, Hu HM, Zimmer A, Lutz B, Mackie K, Bradshaw HB, McCafferty DM, Sharkey KA, Storr M. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflammatory Bowel Diseases. 17: 1651-64. PMID 21744421 DOI: 10.1002/ibd.21538  0.84
2011 Straiker A, Wager-Miller J, Hu SS, Blankman JL, Cravatt BF, Mackie K. COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation. British Journal of Pharmacology. 164: 1672-83. PMID 21564090 DOI: 10.1111/j.1476-5381.2011.01486.x  0.84
2011 Hemmings HC, Mackie K. The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation. Anesthesiology. 114: 1277-9. PMID 21532461 DOI: 10.1097/ALN.0b013e31821c647d  0.84
2011 Mulder J, Zilberter M, Pasquaré SJ, Alpár A, Schulte G, Ferreira SG, Köfalvi A, Martín-Moreno AM, Keimpema E, Tanila H, Watanabe M, Mackie K, Hortobágyi T, de Ceballos ML, Harkany T. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a Journal of Neurology. 134: 1041-60. PMID 21459826 DOI: 10.1093/brain/awr046  0.84
2011 Richards AL, Lietz CB, Wager-Miller JB, Mackie K, Trimpin S. Imaging mass spectrometry in transmission geometry Rapid Communications in Mass Spectrometry. 25: 815-820. PMID 21337644 DOI: 10.1002/rcm.4927  0.84
2011 Atwood BK, Lee D, Straiker A, Widlanski TS, Mackie K. CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. European Journal of Pharmacology. 659: 139-45. PMID 21333643 DOI: 10.1016/j.ejphar.2011.01.066  0.84
2011 Atwood BK, Lopez J, Wager-Miller J, Mackie K, Straiker A. Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. Bmc Genomics. 12: 14. PMID 21214938 DOI: 10.1186/1471-2164-12-14  0.84
2011 Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG. Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. Journal of Neurophysiology. 105: 958-63. PMID 21084685 DOI: 10.1152/jn.00980.2010  0.84
2011 Ludányi A, Hu SS, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. Neuroscience. 174: 50-63. PMID 21035522 DOI: 10.1016/j.neuroscience.2010.10.062  0.84
2011 Halleskog C, Mulder J, Dahlström J, Mackie K, Hortobágyi T, Tanila H, Kumar Puli L, Färber K, Harkany T, Schulte G. WNT signaling in activated microglia is proinflammatory. Glia. 59: 119-31. PMID 20967887 DOI: 10.1002/glia.21081  0.84
2011 Inutan ED, Richards AL, Wager-Miller J, Mackie K, McEwen CN, Trimpin S. Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation Molecular and Cellular Proteomics. 10. PMID 20855542 DOI: 10.1074/mcp.M110.000760  0.84
2011 Atwood B, MacKie K. Reply by authors to letter from Ashton British Journal of Pharmacology. 163: 1114. DOI: 10.1111/j.1476-5381.2010.01140.x  0.84
2011 Ludányi A, Hu SSJ, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Corrigendum to "Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus". [Neuroscience 174 (2011) 50-63]. Neuroscience. 186: 220. DOI: 10.1016/j.neuroscience.2011.04.072  0.84
2010 Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CBâ‚‚. Pharmacological Reviews. 62: 588-631. PMID 21079038 DOI: 10.1124/pr.110.003004  0.84
2010 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC. Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. The European Journal of Neuroscience. 32: 693-706. PMID 21050275 DOI: 10.1111/j.1460-9568.2010.07337.x  0.84
2010 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T. Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13992-4007. PMID 20962221 DOI: 10.1523/JNEUROSCI.2126-10.2010  0.84
2010 Dmitrieva N, Nagabukuro H, Resuehr D, Zhang G, McAllister SL, McGinty KA, Mackie K, Berkley KJ. Endocannabinoid involvement in endometriosis. Pain. 151: 703-10. PMID 20833475 DOI: 10.1016/j.pain.2010.08.037  0.84
2010 Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, ... ... Mackie K, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature Neuroscience. 13: 951-7. PMID 20657592 DOI: 10.1038/nn.2601  0.84
2010 Hu SS, Arnold A, Hutchens JM, Radicke J, Cravatt BF, Wager-Miller J, Mackie K, Straiker A. Architecture of cannabinoid signaling in mouse retina. The Journal of Comparative Neurology. 518: 3848-66. PMID 20653038 DOI: 10.1002/cne.22429  0.84
2010 Maglóczky Z, Tóth K, Karlócai R, Nagy S, Eross L, Czirják S, Vajda J, Rásonyi G, Kelemen A, Juhos V, Halász P, Mackie K, Freund TF. Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. Epilepsia. 51: 115-20. PMID 20618415 DOI: 10.1111/j.1528-1167.2010.02624.x  0.84
2010 Mukhopadhyay P, Pan H, Rajesh M, Bátkai S, Patel V, Harvey-White J, Mukhopadhyay B, Haskó G, Gao B, Mackie K, Pacher P. CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. British Journal of Pharmacology. 160: 657-68. PMID 20590569 DOI: 10.1111/j.1476-5381.2010.00769.x  0.84
2010 Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. British Journal of Pharmacology. 160: 467-79. PMID 20590558 DOI: 10.1111/j.1476-5381.2010.00729.x  0.84
2010 Alexander SP, Mackie K, Ross RA. Themed issue: cannabinoids. British Journal of Pharmacology. 160: 421-2. PMID 20590554 DOI: 10.1111/j.1476-5381.2010.00831.x  0.84
2010 Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SH, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6273-81. PMID 20445053 DOI: 10.1523/JNEUROSCI.2648-09.2010  0.84
2010 Mukhopadhyay B, Liu J, Osei-Hyiaman D, Godlewski G, Mukhopadhyay P, Wang L, Jeong WI, Gao B, Duester G, Mackie K, Kojima S, Kunos G. Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-γ Journal of Biological Chemistry. 285: 19002-19011. PMID 20410309 DOI: 10.1074/jbc.M109.068460  0.84
2010 Storr MA, Bashashati M, Hirota C, Vemuri VK, Keenan CM, Duncan M, Lutz B, Mackie K, Makriyannis A, Macnaughton WK, Sharkey KA. Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 787-96, e223. PMID 20180825 DOI: 10.1111/j.1365-2982.2010.01478.x  0.84
2010 Roche M, Johnston P, Mhuircheartaigh ON, Olango WM, Mackie K, Finn DP. Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear. European Journal of Pain (London, England). 14: 487-95. PMID 19786358 DOI: 10.1016/j.ejpain.2009.08.009  0.84
2010 Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SHR, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice (Journal of Neuroscience (2010) (6273-6281)) Journal of Neuroscience. 30.  0.84
1998 Felder CC, Joyce KE, Briley EM, Glass M, Mackie KP, Fahey KJ, Cullinan GJ, Hunden DC, Johnson DW, Chaney MO, Koppel GA, Brownstein M. LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation. The Journal of Pharmacology and Experimental Therapeutics. 284: 291-7. PMID 9435190  0.84
1997 Baguley WA, Hay WT, Mackie KP, Cheney FW, Cullen BF. Cardiac dysrhythmias associated with the intravenous administration of ondansetron and metoclopramide. Anesthesia and Analgesia. 84: 1380-1. PMID 9174325 DOI: 10.1097/00000539-199706000-00038  0.84
1989 Mackie KP, Nairn AC, Hampel G, Lam G, Jaffe EA. Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells. The Journal of Biological Chemistry. 264: 1748-53. PMID 2536373  0.84
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