Kenneth P. Mackie - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cannabinoid receptors and signaling

285 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ao Z, Cai H, Wu Z, Song S, Karahan H, Kim B, Lu HC, Kim J, Mackie K, Guo F. Tubular human brain organoids to model microglia-mediated neuroinflammation. Lab On a Chip. PMID 34021557 DOI: 10.1039/d1lc00030f  0.52
2021 Tortoriello G, Beiersdorf J, Romani S, Williams G, Cameron GA, Mackie K, Williams MJ, Di Marzo V, Keimpema E, Doherty P, Harkany T. Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in . Cannabis and Cannabinoid Research. 6: 119-136. PMID 33912677 DOI: 10.1089/can.2020.0010  0.48
2021 Hermes DJ, Yadav-Samudrala BJ, Xu C, Paniccia JE, Meeker RB, Armstrong ML, Reisdorph N, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Lysle DT, Fitting S. GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration. Experimental Neurology. 113699. PMID 33736974 DOI: 10.1016/j.expneurol.2021.113699  0.64
2021 Dvorakova M, Kubik-Zahorodna A, Straiker A, Sedlacek R, Hajkova A, Mackie K, Blahos J. SGIP1 is involved in regulation of emotionality, mood, and nociception and tunes in vivo signaling of Cannabinoid Receptor 1. British Journal of Pharmacology. PMID 33491188 DOI: 10.1111/bph.15383  0.84
2020 Zavala CA, Thomaz AC, Iyer V, Mackie K, Hohmann AG. Cannabinoid CB Receptor Activation Attenuates Fentanyl-Induced Respiratory Depression. Cannabis and Cannabinoid Research. PMID 33998863 DOI: 10.1089/can.2020.0059  0.44
2020 Lu HC, Mackie K. Review of the Endocannabinoid System. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 32980261 DOI: 10.1016/j.bpsc.2020.07.016  0.52
2020 Iyer V, Slivicki RA, Thomaz AC, Crystal JD, Mackie K, Hohmann AG. The cannabinoid CB receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence. European Journal of Pharmacology. 886: 173544. PMID 32896549 DOI: 10.1016/J.Ejphar.2020.173544  0.44
2020 László ZI, Lele Z, Zöldi M, Miczán V, Mógor F, Simon GM, Mackie K, Kacskovics I, Cravatt BF, Katona I. ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nature Communications. 11: 4363. PMID 32868797 DOI: 10.1038/S41467-020-18175-4  0.64
2020 Trimpin S, Marshall DD, Karki S, Madarshahian S, Hoang K, Meher AK, Pophristic M, Richards AL, Lietz CB, Fischer JL, Elia EA, Wang B, Pagnotti VS, Lutomski CA, El-Baba TJ, ... ... Mackie K, et al. An Overview of Biological Applications and Fundamentals of New Inlet and Vacuum Ionization Technologies. Rapid Communications in Mass Spectrometry : Rcm. e8829. PMID 32402102 DOI: 10.1002/Rcm.8829  0.76
2020 Wager-Miller J, Green MM, Shafique H, Mackie K. Collection of Frozen Rodent Brain Regions for Downstream Analyses. Journal of Visualized Experiments. PMID 32391813 DOI: 10.3791/60474  0.76
2020 Moussa-Tooks AB, Larson ER, Gimeno AF, Leishman E, Bartolomeo LA, Bradshaw HB, Green JT, O'Donnell BF, Mackie K, Hetrick WP. Long-Term Aberrations To Cerebellar Endocannabinoids Induced By Early-Life Stress. Scientific Reports. 10: 7236. PMID 32350298 DOI: 10.1038/S41598-020-64075-4  0.52
2020 Farkas E, Varga E, Kovács B, Szilvásy-Szabó A, Cote-Vélez A, Péterfi Z, Matziari M, Tóth M, Zelena D, Mezriczky Z, Kádár A, Kővári D, Watanabe M, Kano M, Mackie K, et al. A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System. Iscience. 23: 100921. PMID 32143135 DOI: 10.1016/J.Isci.2020.100921  0.36
2020 Marcus DJ, Bedse G, Gaulden AD, Ryan JD, Kondev V, Winters ND, Rosas-Vidal LE, Altemus M, Mackie K, Lee FS, Delpire E, Patel S. Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening. Neuron. PMID 31948734 DOI: 10.1016/J.Neuron.2019.12.024  0.8
2019 Henderson-Redmond AN, Nealon CM, Davis BJ, Yuill MB, Sepulveda DE, Blanton H, Piscura MK, Zee ML, Haskins CP, Marcus DJ, Mackie K, Guindon J, Morgan DJ. c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner. Neuropharmacology. 107847. PMID 31758947 DOI: 10.1016/j.neuropharm.2019.107847  0.8
2019 Garai S, Kulkarni PM, Schaffer PC, Leo L, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, ... ... Mackie K, et al. Application of Fluorine- And Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of CB1 Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31756109 DOI: 10.1021/Acs.Jmedchem.9B01142  0.84
2019 Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, ... Mackie K, et al. Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy. Molecular Psychiatry. PMID 31735910 DOI: 10.1038/S41380-019-0580-4  0.48
2019 Scheyer AF, Borsoi M, Wager-Miller J, Pelissier-Alicot AL, Murphy MN, Mackie K, Manzoni OJJ. Cannabinoid Exposure via Lactation in Rats Disrupts Perinatal Programming of the Gamma-Aminobutyric Acid Trajectory and Select Early-Life Behaviors. Biological Psychiatry. PMID 31653479 DOI: 10.1016/j.biopsych.2019.08.023  0.76
2019 Jacobs IR, Xu C, Hermes DJ, League AF, Xu C, Nath B, Jiang W, Niphakis MJ, Cravatt BF, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Inhibitory Control Deficits Associated with Upregulation of CBR in the HIV-1 Tat Transgenic Mouse Model of Hand. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 31372820 DOI: 10.1007/S11481-019-09867-W  0.64
2019 Wang ZJ, Hu SS, Bradshaw HB, Sun L, Mackie K, Straiker A, Heinbockel T. Cannabinoid Receptor-Mediated Modulation of Inhibitory Inputs to Mitral Cells in the Main Olfactory Bulb. Journal of Neurophysiology. PMID 31215302 DOI: 10.1152/Jn.00100.2018  0.84
2019 Leishman E, Mackie K, Bradshaw HB. Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. Frontiers in Molecular Neuroscience. 12: 142. PMID 31213981 DOI: 10.3389/fnmol.2019.00142  0.52
2019 Murataeva N, Daily L, Taylor X, Dhopeshwarkar A, Hu SS, Miller S, McHugh D, Oehler O, Li S, Bonanno JA, Mackie K, Straiker A. Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea. Cornea. PMID 30969262 DOI: 10.1097/Ico.0000000000001934  0.84
2019 Mackie K, Ford C, Stella N. Decision letter: Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion Elife. DOI: 10.7554/Elife.47209.021  0.8
2018 Leishman E, Murphy MN, Murphy MI, Mackie K, Bradshaw HB. Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains. Frontiers in Molecular Neuroscience. 11: 436. PMID 30542263 DOI: 10.3389/fnmol.2018.00436  0.52
2018 Leishman E, Manchanda M, Thelen R, Miller S, Mackie K, Bradshaw HB. Cannabidiol's Upregulation of -acyl Ethanolamines in the Central Nervous System Requires -acyl Phosphatidyl Ethanolamine-Specific Phospholipase D. Cannabis and Cannabinoid Research. 3: 228-241. PMID 30515459 DOI: 10.1089/can.2018.0031  0.52
2018 Li AL, Lin X, Dhopeshwarkar AS, Thomaz AC, Carey LM, Liu Y, Nikas SP, Makriyannis A, Mackie K, Hohmann AG. The cannabinoid CB2 agonist AM1710 differentially suppresses distinct pathological pain states and attenuates morphine tolerance and withdrawal. Molecular Pharmacology. PMID 30504240 DOI: 10.1124/Mol.118.113233  0.76
2018 Bara A, Manduca A, Bernabeu A, Borsoi M, Serviado M, Lassalle O, Murphy MN, Wager-Miller J, Mackie K, Pelissier-Alicot AL, Trezza V, Manzoni OJ. Sex-dependent effects of in utero cannabinoid exposure on cortical function. Elife. 7. PMID 30201092 DOI: 10.7554/Elife.36234  0.76
2018 Liu Y, Ji L, Eno M, Kudalkar S, Li A, Schimpgen M, Benchama O, Morales P, Xu S, Hurst DP, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis D, ... ... Mackie K, et al. (R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. Journal of Medicinal Chemistry. PMID 30196704 DOI: 10.1021/Acs.Jmedchem.8B00611  0.76
2018 Hermes DJ, Xu C, Poklis JL, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology. PMID 30114402 DOI: 10.1016/J.Neuropharm.2018.08.013  0.64
2018 Miller S, Kulkarni S, Ciesielski A, Nikas SP, Mackie K, Makriyannis A, Straiker A. Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure. Pharmaceuticals (Basel, Switzerland). 11. PMID 29786643 DOI: 10.3390/Ph11020050  0.84
2018 Straiker A, Dvorakova M, Zimmowitch A, Mackie KP. Cannabidiol inhibits endocannabinoid signaling in autaptic hippocampal neurons. Molecular Pharmacology. PMID 29669714 DOI: 10.1124/mol.118.111864  0.84
2018 Leishman E, Murphy M, Mackie K, Bradshaw HB. Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult. Biochimica Et Biophysica Acta. 1863: 479-492. PMID 29408467 DOI: 10.1016/j.bbalip.2018.02.001  0.52
2018 Bara A, Manduca A, Bernabeu A, Borsoi M, Serviado M, Lassalle O, Murphy M, Wager-Miller J, Mackie K, Pelissier-Alicot A, Trezza V, Manzoni OJ. Author response: Sex-dependent effects of in utero cannabinoid exposure on cortical function Elife. DOI: 10.7554/Elife.36234.025  0.76
2017 Lin X, Dhopeshwarkar AS, Huibregtse M, Mackie K, Hohmann AG. The slowly signaling G protein-biased CB2 cannabinoid receptor agonist LY2828360 suppresses neuropathic pain with sustained efficacy and attenuates morphine tolerance and dependence. Molecular Pharmacology. PMID 29192123 DOI: 10.1124/Mol.117.109355  0.44
2017 Westphal M, Schafroth MA, Sarott R, Imhof M, Bold C, Leippe P, Dhopeshwarkar A, Grandner J, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA. Synthesis of Photoswitchable Δ(9)-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. Journal of the American Chemical Society. PMID 29161035 DOI: 10.1021/Jacs.7B06456  0.76
2017 Mitjavila J, Yin D, Kulkarni PM, Zanato C, Thakur GA, Ross R, Greig I, Mackie K, Straiker A. Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons. Pharmacological Research. PMID 29158048 DOI: 10.1016/j.phrs.2017.11.019  0.84
2017 Jourdan T, Park JK, Varga ZV, Pálóczi J, Coffey NJ, Rosenberg AZ, Godlewski G, Cinar R, Mackie K, Pacher P, Kunos G. Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy. Diabetes, Obesity & Metabolism. PMID 29106063 DOI: 10.1111/Dom.13150  0.44
2017 Murphy M, Mills S, Winstone J, Leishman E, Wager-Miller J, Bradshaw H, Mackie K. Chronic Adolescent Δ(9)-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment. Cannabis and Cannabinoid Research. 2: 235-246. PMID 29098186 DOI: 10.1089/can.2017.0034  0.76
2017 Slivicki RA, Xu Z, Kulkarni PM, Pertwee RG, Mackie K, Thakur GA, Hohmann AG. Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence. Biological Psychiatry. PMID 28823711 DOI: 10.1016/J.Biopsych.2017.06.032  0.44
2017 Xu C, Hermes DJ, Nwanguma B, Jacobs IR, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska B, Fitting S. Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Molecular and Cellular Neurosciences. PMID 28733129 DOI: 10.1016/J.Mcn.2017.07.003  0.32
2017 Ruehle S, Wager-Miller J, Straiker A, Farnsworth J, Murphy MN, Loch S, Monory K, Mackie K, Lutz B. Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse. Journal of Neurochemistry. PMID 28608535 DOI: 10.1111/jnc.14099  0.84
2017 Miller S, Hu SS, Leishman E, Morgan D, Wager-Miller J, Mackie K, Bradshaw HB, Straiker A. A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner. Investigative Ophthalmology & Visual Science. 58: 2930-2938. PMID 28593245 DOI: 10.1167/iovs.16-21330  0.84
2017 Li AL, Carey LM, Mackie K, Hohmann AG. The cannabinoid CB2 agonist GW405833 suppresses inflammatory and neuropathic pain through a CB1 mechanism that is independent of CB2 receptors in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 28592614 DOI: 10.1124/Jpet.117.241901  0.44
2017 Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. PMID 28527758 DOI: 10.1016/J.Neuropharm.2017.05.018  0.8
2017 Carey LM, Gutierrez T, Deng L, Lee WH, Mackie K, Hohmann AG. Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice. Scientific Reports. 7: 944. PMID 28428628 DOI: 10.1038/s41598-017-01062-2  0.44
2017 Marcus DJ, Henderson-Redmond AN, Gonek M, Zee ML, Farnsworth JC, Amin RA, Andrews MJ, Davis BJ, Mackie K, Morgan DJ. Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. Plos One. 12: e0174826. PMID 28426670 DOI: 10.1371/journal.pone.0174826  0.8
2017 Cinar R, Gochuico BR, Iyer MR, Jourdan T, Yokoyama T, Park JK, Coffey NJ, Pri-Chen H, Szanda G, Liu Z, Mackie K, Gahl WA, Kunos G. Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. Jci Insight. 2. PMID 28422760 DOI: 10.1172/jci.insight.92281  0.32
2017 Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, et al. Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nature Communications. 8: 14782. PMID 28348378 DOI: 10.1038/Ncomms14782  0.8
2016 Dhopeshwarkar A, Murataeva N, Makriyannis A, Straiker A, Mackie KP. Two Janus cannabinoids that are both CB2 agonists and CB1 antagonists. The Journal of Pharmacology and Experimental Therapeutics. PMID 27927913 DOI: 10.1124/Jpet.116.236539  0.84
2016 Fung S, Xu C, Hamel E, Wager-Miller JB, Woodruff G, Miller A, Sanford C, Mackie K, Stella N. Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration. Pharmacological Research. PMID 27832960 DOI: 10.1016/j.phrs.2016.10.025  0.8
2016 Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. Eneuro. 3. PMID 27517090 DOI: 10.1523/ENEURO.0160-16.2016  0.8
2016 Marcus DJ, Zee ML, Davis BJ, Haskins CP, Andrews MJ, Amin R, Henderson-Redmond AN, Mackie K, Czyzyk TA, Morgan DJ. Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic. Plos One. 11: e0160462. PMID 27501235 DOI: 10.1371/Journal.Pone.0160462  0.8
2016 Tung LW, Lu GL, Lee YH, Yu L, Lee HJ, Leishman E, Bradshaw H, Hwang LL, Hung MS, Mackie K, Zimmer A, Chiou LC. Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons. Nature Communications. 7: 12199. PMID 27448020 DOI: 10.1038/ncomms12199  0.8
2016 Wager-Miller J, Mackie K. Quantitation of Plasma Membrane (G Protein-Coupled) Receptor Trafficking in Cultured Cells Methods of Molecular Biology. 1412: 255-266. PMID 27245911 DOI: 10.1007/978-1-4939-3539-0_26  0.76
2016 Wager-Miller J, Mackie K. Western Blotting of the Endocannabinoid System Methods of Molecular Biology. 1412: 247-254. PMID 27245910 DOI: 10.1007/978-1-4939-3539-0_25  0.76
2016 Dhopeshwarkar A, Mackie K. Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway. Journal of Pharmacology and Experimental Therapeutics. 358: 342-351. PMID 27194477 DOI: 10.1124/Jpet.116.232561  0.76
2016 Carey LM, Slivicki RA, Leishman E, Cornett B, Mackie K, Bradshaw H, Hohmann AG. A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular Pain. 12. PMID 27178246 DOI: 10.1177/1744806916649192  0.52
2016 Murataeva N, Dhopeshwarkar A, Yin D, Mitjavila J, Bradshaw H, Straiker A, Mackie K. WHERE's MY ENTOURAGE? THE CURIOUS CASE OF 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. Pharmacological Research. PMID 27117667 DOI: 10.1016/J.Phrs.2016.04.015  0.8
2016 Leishman E, Cornett B, Spork K, Straiker A, Mackie K, Bradshaw HB. Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain. Pharmacological Research. PMID 27109320 DOI: 10.1016/j.phrs.2016.04.020  0.84
2016 Marshall DD, Inutan ED, Wang B, Liu CW, Thawoos S, Wager-Miller J, Mackie K, Trimpin S. A broad-based study on hyphenating new ionization technologies with MS/MS for PTM's and tissue characterization. Proteomics. PMID 27093917 DOI: 10.1002/Pmic.201500530  0.8
2016 Delgado-Peraza F, Ahn K, Nogueras-Ortiz C, Mungrue I, Mackie KP, Kendall DA, Yudowski G. Mechanisms of biased beta-arrestin mediated signaling downstream from the cannabinoid 1 receptor. Molecular Pharmacology. PMID 27009233 DOI: 10.1124/Mol.115.103176  0.8
2016 Wang Y, Gu N, Duan T, Kesner P, Blaskovits F, Liu J, Lu Y, Tong L, Gao F, Harris C, Mackie K, Li J, Tan Q, Hill MN, Yuan Z, et al. Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses. Molecular Psychiatry. PMID 27001616 DOI: 10.1038/Mp.2016.22  0.32
2016 Xu C, Hermes DJ, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 26993829 DOI: 10.1007/S11481-016-9664-Y  0.8
2016 Leishman E, Mackie K, Luquet S, Bradshaw HB. Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. Biochimica Et Biophysica Acta. 1861: 491-500. PMID 26956082 DOI: 10.1016/j.bbalip.2016.03.003  0.52
2016 Devereaux ZJ, Reynolds CA, Foley CD, Fischer JL, DeLeeuw JL, Wager-Miller J, Narayan SB, Mackie K, Trimpin S. Matrix-Assisted Ionization (MAI) on a Portable Mass Spectrometer: Analysis Directly from Biological and Synthetic Materials. Analytical Chemistry. PMID 26938428 DOI: 10.1021/Acs.Analchem.6B00304  0.76
2016 Lee HJ, Chang LY, Ho YC, Teng SF, Hwang LL, Mackie K, Chiou LC. Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray. Neuropharmacology. PMID 26907809 DOI: 10.1016/j.neuropharm.2016.02.018  0.8
2015 Lu HC, Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry. PMID 26698193 DOI: 10.1016/j.biopsych.2015.07.028  0.84
2015 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Björklund P, Mackie K, Di Marzo V, Hökfelt TG, Dobrzyn A, Harkany T. Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proceedings of the National Academy of Sciences of the United States of America. PMID 26494286 DOI: 10.1073/Pnas.1519040112  0.48
2015 Hu SS, Mackie K. Distribution of the Endocannabinoid System in the Central Nervous System. Handbook of Experimental Pharmacology. 231: 59-93. PMID 26408158 DOI: 10.1007/978-3-319-20825-1_3  0.84
2015 Wang B, Dearring CL, Wager-Miller J, Mackie K, Trimpin S. Drug detection and quantification directly from tissue using novel ionization methods for mass spectrometry. European Journal of Mass Spectrometry (Chichester, England). 21: 201-10. PMID 26307700 DOI: 10.1255/Ejms.1338  0.8
2015 Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model. Pharmacological Research. 99: 370-6. PMID 26211948 DOI: 10.1016/j.phrs.2015.07.017  0.84
2015 Ballinger MD, Saito A, Abazyan B, Taniguchi Y, Huang CH, Ito K, Zhu X, Segal H, Jaaro-Peled H, Sawa A, Mackie K, Pletnikov MV, Kamiya A. Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory. Neurobiology of Disease. PMID 26093170 DOI: 10.1016/J.Nbd.2015.06.006  0.84
2015 Marcus DJ, Zee M, Hughes A, Yuill MB, Hohmann AG, Mackie K, Guindon J, Morgan DJ. Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase. Molecular Pain. 11: 34. PMID 26065412 DOI: 10.1186/s12990-015-0031-4  0.84
2015 Murataeva N, Li S, Oehler O, Miller S, Dhopeshwarkar A, Hu SS, Bonanno JA, Bradshaw H, Mackie K, McHugh D, Straiker A. Cannabinoid-induced chemotaxis in bovine corneal epithelial cells. Investigative Ophthalmology & Visual Science. 56: 3304-13. PMID 26024113 DOI: 10.1167/Iovs.14-15675  0.8
2015 Lovelace JW, Corches A, Vieira PA, Hiroto AS, Mackie K, Korzus E. An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity. Neuropharmacology. 99: 242-255. PMID 25979486 DOI: 10.1016/J.Neuropharm.2015.04.034  0.8
2015 Janero DR, Yaddanapudi S, Zvonok N, Subramanian KV, Shukla VG, Stahl E, Zhou L, Hurst D, Wager-Miller J, Bohn LM, Reggio PH, Mackie K, Makriyannis A. Molecular-Interaction and Signaling Profiles of AM3677, a Novel Covalent Agonist Selective for the Cannabinoid 1 Receptor. Acs Chemical Neuroscience. PMID 25978068 DOI: 10.1021/Acschemneuro.5B00090  0.8
2015 Deng L, Cornett BL, Mackie K, Hohmann AG. CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain. Molecular Pharmacology. 88: 64-74. PMID 25904556 DOI: 10.1124/mol.115.098483  0.8
2015 Bashashati M, Nasser Y, Keenan CM, Ho W, Piscitelli F, Nalli M, Mackie K, Storr MA, Di Marzo V, Sharkey KA. Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. British Journal of Pharmacology. 172: 3099-111. PMID 25684407 DOI: 10.1111/Bph.13114  0.84
2015 Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE. Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Molecular Pharmacology. 87: 747-65. PMID 25657338 DOI: 10.1124/Mol.114.096495  0.8
2015 Mukhopadhyay B, Schuebel K, Mukhopadhyay P, Cinar R, Godlewski G, Xiong K, Mackie K, Lizak M, Yuan Q, Goldman D, Kunos G. Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology (Baltimore, Md.). 61: 1615-26. PMID 25580584 DOI: 10.1002/Hep.27686  0.84
2015 Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner. British Journal of Pharmacology. 172: 2406-18. PMID 25572435 DOI: 10.1111/Bph.13069  0.84
2015 Deng L, Guindon J, Cornett BL, Makriyannis A, Mackie K, Hohmann AG. Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal. Biological Psychiatry. 77: 475-87. PMID 24853387 DOI: 10.1016/j.biopsych.2014.04.009  0.84
2015 Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model Pharmacological Research. 99: 370-376. DOI: 10.1016/j.phrs.2015.07.017  0.84
2015 Reyes BAS, Heldt NA, Mackie K, Van Bockstaele EJ. Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons Neuroscience. 303: 323-337. DOI: 10.1016/j.neuroscience.2015.07.009  0.84
2014 Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T. Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature Reviews. Neuroscience. 15: 786-801. PMID 25409697 DOI: 10.1038/Nrn3846  0.84
2014 Melis M, Sagheddu C, De Felice M, Casti A, Madeddu C, Spiga S, Muntoni AL, Mackie K, Marsicano G, Colombo G, Castelli MP, Pistis M. Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12716-24. PMID 25232109 DOI: 10.1523/Jneurosci.1844-14.2014  0.84
2014 Cathel AM, Reyes BA, Wang Q, Palma J, Mackie K, Van Bockstaele EJ, Kirby LG. Cannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortex. The European Journal of Neuroscience. 40: 3202-14. PMID 25131562 DOI: 10.1111/ejn.12690  0.84
2014 Dhopeshwarkar A, Mackie K. CB2cannabinoid receptors as a therapeutic target-what does the future hold? Molecular Pharmacology. 86: 430-437. PMID 25106425 DOI: 10.1124/Mol.114.094649  0.84
2014 Flores-Otero J, Ahn KH, Delgado-Peraza F, Mackie K, Kendall DA, Yudowski GA. Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature Communications. 5: 4589. PMID 25081814 DOI: 10.1038/Ncomms5589  0.84
2014 Lutomski CA, El-Baba TJ, Inutan ED, Manly CD, Wager-Miller J, Mackie K, Trimpin S. Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet. Analytical Chemistry. 86: 6208-13. PMID 24896880 DOI: 10.1021/Ac501788P  0.76
2014 Wu CS, Morgan D, Jew CP, Haskins C, Andrews MJ, Leishman E, Spencer CM, Czyzyk T, Bradshaw H, Mackie K, Lu HC. Long-term consequences of perinatal fatty acid amino hydrolase inhibition. British Journal of Pharmacology. 171: 1420-34. PMID 24730060 DOI: 10.1111/Bph.12500  0.84
2014 Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K. Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5152-63. PMID 24719095 DOI: 10.1523/Jneurosci.3445-12.2014  0.84
2014 Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S. Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron. 81: 1111-25. PMID 24607231 DOI: 10.1016/J.Neuron.2014.01.012  0.84
2014 O'Donnell BF, Mackie K. The mismatch negativity: a translational probe of auditory processing in cannabis users. Biological Psychiatry. 75: 428-9. PMID 24560430 DOI: 10.1016/j.biopsych.2014.01.015  0.84
2014 Hernández-Castellanos JM, Vivas O, Garduño J, De la Cruz L, Arenas I, Elías-Viñas D, Mackie K, García DE. Gβ₂ mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons. Biochemical and Biophysical Research Communications. 445: 250-4. PMID 24513289 DOI: 10.1016/j.bbrc.2014.01.192  0.84
2014 Lovelace JW, Vieira PA, Corches A, Mackie K, Korzus E. Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1685-93. PMID 24457285 DOI: 10.1038/Npp.2014.15  0.84
2014 Murataeva N, Straiker A, Mackie K. Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. British Journal of Pharmacology. 171: 1379-91. PMID 24102242 DOI: 10.1111/Bph.12411  0.84
2014 Lutomski CA, El-Baba TJ, Inutan ED, Manly CD, Wager-Miller J, Mackie K, Trimpin S. Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet Analytical Chemistry. 86: 6208-6213. DOI: 10.1021/ac501788p  0.84
2013 Cluny NL, Baraboi ED, Mackie K, Burdyga G, Richard D, Dockray GJ, Sharkey KA. High fat diet and body weight have different effects on cannabinoid CB(1) receptor expression in rat nodose ganglia. Autonomic Neuroscience : Basic & Clinical. 179: 122-30. PMID 24145047 DOI: 10.1016/J.Autneu.2013.09.015  0.84
2013 Petrov RR, Knight L, Chen SR, Wager-Miller J, McDaniel SW, Diaz F, Barth F, Pan HL, Mackie K, Cavasotto CN, Diaz P. Mastering tricyclic ring systems for desirable functional cannabinoid activity. European Journal of Medicinal Chemistry. 69: 881-907. PMID 24125850 DOI: 10.1016/j.ejmech.2013.09.038  0.84
2013 Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A. CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. The Journal of Biological Chemistry. 288: 32685-99. PMID 24089517 DOI: 10.1074/Jbc.M113.478354  0.84
2013 Chen DH, Naydenov A, Blankman JL, Mefford HC, Davis M, Sul Y, Barloon AS, Bonkowski E, Wolff J, Matsushita M, Smith C, Cravatt BF, Mackie K, Raskind WH, Stella N, et al. Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects. Human Mutation. 34: 1672-8. PMID 24027063 DOI: 10.1002/Humu.22437  0.84
2013 Garzón M, Duffy AM, Chan J, Lynch MK, Mackie K, Pickel VM. Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area. Neuroscience. 252: 126-43. PMID 23954803 DOI: 10.1016/J.Neuroscience.2013.08.008  0.84
2013 Jain T, Wager-Miller J, Mackie K, Straiker A. Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Molecular Pharmacology. 84: 296-302. PMID 23748223 DOI: 10.1124/mol.113.085217  0.84
2013 Cristino L, Busetto G, Imperatore R, Ferrandino I, Palomba L, Silvestri C, Petrosino S, Orlando P, Bentivoglio M, Mackie K, Di Marzo V. Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: E2229-38. PMID 23630288 DOI: 10.1073/Pnas.1219485110  0.84
2013 Li K, Fichna J, Schicho R, Saur D, Bashashati M, Mackie K, Li Y, Zimmer A, Göke B, Sharkey KA, Storr M. A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology. 71: 255-63. PMID 23603203 DOI: 10.1016/J.Neuropharm.2013.03.029  0.84
2013 Straiker A, Min KT, Mackie K. Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons. Neurobiology of Disease. 56: 1-5. PMID 23578490 DOI: 10.1016/J.Nbd.2013.04.002  0.84
2013 Wu CS, Chen H, Sun H, Zhu J, Jew CP, Wager-Miller J, Straiker A, Spencer C, Bradshaw H, Mackie K, Lu HC. GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. Plos One. 8: e60314. PMID 23565223 DOI: 10.1371/journal.pone.0060314  0.84
2013 Cottone E, Pomatto V, Cerri F, Campantico E, Mackie K, Delpero M, Guastalla A, Dati C, Bovolin P, Franzoni MF. Cannabinoid receptors are widely expressed in goldfish: Molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs Fish Physiology and Biochemistry. 39: 1287-1296. PMID 23504102 DOI: 10.1007/s10695-013-9783-9  0.84
2013 Shonesy BC, Wang X, Rose KL, Ramikie TS, Cavener VS, Rentz T, Baucum AJ, Jalan-Sakrikar N, Mackie K, Winder DG, Patel S, Colbran RJ. CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling. Nature Neuroscience. 16: 456-63. PMID 23502535 DOI: 10.1038/Nn.3353  0.84
2013 Fitzgerald ML, Mackie K, Pickel VM. The impact of adolescent social isolation on dopamine D2 and cannabinoid CB1 receptors in the adult rat prefrontal cortex. Neuroscience. 235: 40-50. PMID 23333674 DOI: 10.1016/J.Neuroscience.2013.01.021  0.84
2013 Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 1935-40. PMID 23319656 DOI: 10.1073/Pnas.1212563110  0.84
2013 Horne EA, Coy J, Swinney K, Fung S, Cherry AE, Marrs WR, Naydenov AV, Lin YH, Sun X, Keene CD, Grouzmann E, Muchowski P, Bates GP, Mackie K, Stella N. Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European Journal of Neuroscience. 37: 429-40. PMID 23167744 DOI: 10.1111/Ejn.12045  0.84
2013 Veress G, Meszar Z, Muszil D, Avelino A, Matesz K, Mackie K, Nagy I. Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons. Brain Structure & Function. 218: 733-50. PMID 22618437 DOI: 10.1007/s00429-012-0425-2  0.84
2013 Inutan ED, Wager-Miller J, Narayan SB, Mackie K, Trimpin S. The potential for clinical applications using a new ionization method combined with ion mobility spectrometry-mass spectrometry International Journal For Ion Mobility Spectrometry. 16: 145-159. DOI: 10.1007/S12127-013-0131-7  0.84
2013 Mackie K. Endocannabinoid-mediated synaptic plasticity Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders. 11-24. DOI: 10.1007/978-1-4614-7940-6_2  0.84
2012 Péterfi Z, Urbán GM, Papp OI, Németh B, Monyer H, Szabó G, Erdélyi F, Mackie K, Freund TF, Hájos N, Katona I. Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14448-63. PMID 23055515 DOI: 10.1523/Jneurosci.1676-12.2012  0.84
2012 Hu H, Ho W, Mackie K, Pittman QJ, Sharkey KA. Brain CB₁ receptor expression following lipopolysaccharide-induced inflammation. Neuroscience. 227: 211-22. PMID 23041513 DOI: 10.1016/J.Neuroscience.2012.09.067  0.84
2012 Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature Communications. 3: 1080. PMID 23011134 DOI: 10.1038/Ncomms2045  0.84
2012 Inutan ED, Wager-Miller J, MacKie K, Trimpin S. Laserspray ionization imaging of multiply charged ions using a commercial vacuum MALDI ion source Analytical Chemistry. 84: 9079-9084. PMID 23009673 DOI: 10.1021/Ac301665H  0.84
2012 Murataeva N, Mackie K, Straiker A. The CB2-preferring agonist JWH015 also potently and efficaciously activates CB1 in autaptic hippocampal neurons. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 66: 437-42. PMID 22921769 DOI: 10.1016/J.Phrs.2012.08.002  0.84
2012 Pickel VM, Shobin ET, Lane DA, Mackie K. Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals. Neuroscience. 227: 10-21. PMID 22863674 DOI: 10.1016/j.neuroscience.2012.07.050  0.84
2012 Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9457-68. PMID 22787031 DOI: 10.1523/Jneurosci.0013-12.2012  0.84
2012 Ferreira SG, Teixeira FM, Garção P, Agostinho P, Ledent C, Cortes L, MacKie K, Köfalvi A. Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences Neurochemistry International. 61: 219-226. PMID 22609378 DOI: 10.1016/j.neuint.2012.05.009  0.84
2012 Fitzgerald ML, Chan J, Mackie K, Lupica CR, Pickel VM. Altered dendritic distribution of dopamine D2 receptors and reduction in mitochondrial number in parvalbumin-containing interneurons in the medial prefrontal cortex of cannabinoid-1 (CB1) receptor knockout mice. The Journal of Comparative Neurology. 520: 4013-31. PMID 22592925 DOI: 10.1002/Cne.23141  0.84
2012 Atwood BK, Straiker A, Mackie K. CBâ‚‚ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons. Neuropharmacology. 63: 514-23. PMID 22579668 DOI: 10.1016/J.Neuropharm.2012.04.024  0.84
2012 Hegyi Z, Holló K, Kis G, Mackie K, Antal M. Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. Glia. 60: 1316-29. PMID 22573306 DOI: 10.1002/glia.22351  0.84
2012 Pacher P, Mackie K. Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration Journal of Molecular Medicine. 90: 347-351. PMID 22371074 DOI: 10.1007/s00109-012-0884-1  0.84
2012 Rajesh M, Bátkai S, Kechrid M, Mukhopadhyay P, Lee WS, Horváth B, Holovac E, Cinar R, Liaudet L, Mackie K, Haskó G, Pacher P. Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. Diabetes. 61: 716-27. PMID 22315315 DOI: 10.2337/db11-0477  0.84
2012 Richards AL, Lietz CB, Wager-Miller J, Mackie K, Trimpin S. Localization and imaging of gangliosides in mouse brain tissue sections by laserspray ionization inlet Journal of Lipid Research. 53: 1390-1398. PMID 22262808 DOI: 10.1194/Jlr.D019711  0.84
2012 Hons IM, Storr MA, Mackie K, Lutz B, Pittman QJ, Mawe GM, Sharkey KA. Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: e113-24. PMID 22235973 DOI: 10.1111/J.1365-2982.2011.01860.X  0.84
2012 Keimpema E, Straiker A, Mackie K, Harkany T, Hjerling-Leffler J. Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. The Journal of Physiology. 590: 703-14. PMID 22219340 DOI: 10.1113/Jphysiol.2011.224386  0.84
2012 Atwood BK, Straiker A, Mackie K. CBâ‚‚: therapeutic target-in-waiting. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 16-20. PMID 22197668 DOI: 10.1016/J.Pnpbp.2011.12.001  0.84
2012 Lane DA, Chan J, Fitzgerald ML, Kearn CS, Mackie K, Pickel VM. Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology. 221: 101-13. PMID 22160162 DOI: 10.1007/S00213-011-2553-4  0.84
2012 Atwood BK, Wager-Miller J, Haskins C, Straiker A, Mackie K. Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands. Molecular Pharmacology. 81: 250-63. PMID 22064678 DOI: 10.1124/Mol.111.074013  0.84
2012 Straiker A, Wager-Miller J, Hutchens J, Mackie K. Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2660-71. PMID 22014238 DOI: 10.1111/j.1476-5381.2011.01744.x  0.84
2012 Straiker A, Wager-Miller J, Mackie K. The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2652-9. PMID 22014214 DOI: 10.1111/j.1476-5381.2011.01743.x  0.84
2012 López-Gallardo M, López-Rodríguez AB, Llorente-Berzal Á, Rotllant D, Mackie K, Armario A, Nadal R, Viveros MP. Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion. Neuroscience. 204: 90-103. PMID 22001306 DOI: 10.1016/J.Neuroscience.2011.09.063  0.84
2012 Bashashati M, Storr MA, Nikas SP, Wood JT, Godlewski G, Liu J, Ho W, Keenan CM, Zhang H, Alapafuja SO, Cravatt BF, Lutz B, Mackie K, Kunos G, Patel KD, et al. Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. British Journal of Pharmacology. 165: 1556-71. PMID 21883147 DOI: 10.1111/J.1476-5381.2011.01644.X  0.84
2012 Morgan DJ, Muller CH, Murataeva NA, Davis BJ, Mackie K. Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity. British Journal of Pharmacology. 165: 2575-83. PMID 21615727 DOI: 10.1111/J.1476-5381.2011.01506.X  0.84
2011 Ho YC, Lee HJ, Tung LW, Liao YY, Fu SY, Teng SF, Liao HT, Mackie K, Chiou LC. Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14600-10. PMID 21994376 DOI: 10.1523/Jneurosci.2671-11.2011  0.84
2011 Duffy AM, Fitzgerald ML, Chan J, Robinson DC, Milner TA, Mackie K, Pickel VM. Acetylcholine α7 nicotinic and dopamine D2 receptors are targeted to many of the same postsynaptic dendrites and astrocytes in the rodent prefrontal cortex. Synapse (New York, N.Y.). 65: 1350-67. PMID 21858872 DOI: 10.1002/Syn.20977  0.84
2011 Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ. Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10506-15. PMID 21775596 DOI: 10.1523/Jneurosci.0496-11.2011  0.84
2011 Keimpema E, Mackie K, Harkany T. Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in Pharmacological Sciences. 32: 551-61. PMID 21757242 DOI: 10.1016/J.Tips.2011.05.004  0.84
2011 Schicho R, Bashashati M, Bawa M, McHugh D, Saur D, Hu HM, Zimmer A, Lutz B, Mackie K, Bradshaw HB, McCafferty DM, Sharkey KA, Storr M. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflammatory Bowel Diseases. 17: 1651-64. PMID 21744421 DOI: 10.1002/Ibd.21538  0.84
2011 Straiker A, Wager-Miller J, Hu SS, Blankman JL, Cravatt BF, Mackie K. COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation. British Journal of Pharmacology. 164: 1672-83. PMID 21564090 DOI: 10.1111/J.1476-5381.2011.01486.X  0.84
2011 Hemmings HC, Mackie K. The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation. Anesthesiology. 114: 1277-9. PMID 21532461 DOI: 10.1097/ALN.0b013e31821c647d  0.84
2011 Mulder J, Zilberter M, Pasquaré SJ, Alpár A, Schulte G, Ferreira SG, Köfalvi A, Martín-Moreno AM, Keimpema E, Tanila H, Watanabe M, Mackie K, Hortobágyi T, de Ceballos ML, Harkany T. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a Journal of Neurology. 134: 1041-60. PMID 21459826 DOI: 10.1093/Brain/Awr046  0.84
2011 Richards AL, Lietz CB, Wager-Miller JB, Mackie K, Trimpin S. Imaging mass spectrometry in transmission geometry Rapid Communications in Mass Spectrometry. 25: 815-820. PMID 21337644 DOI: 10.1002/Rcm.4927  0.84
2011 Atwood BK, Lee D, Straiker A, Widlanski TS, Mackie K. CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. European Journal of Pharmacology. 659: 139-45. PMID 21333643 DOI: 10.1016/J.Ejphar.2011.01.066  0.84
2011 Atwood BK, Lopez J, Wager-Miller J, Mackie K, Straiker A. Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. Bmc Genomics. 12: 14. PMID 21214938 DOI: 10.1186/1471-2164-12-14  0.84
2011 Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG. Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. Journal of Neurophysiology. 105: 958-63. PMID 21084685 DOI: 10.1152/Jn.00980.2010  0.84
2011 Ludányi A, Hu SS, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. Neuroscience. 174: 50-63. PMID 21035522 DOI: 10.1016/J.Neuroscience.2010.10.062  0.84
2011 Halleskog C, Mulder J, Dahlström J, Mackie K, Hortobágyi T, Tanila H, Kumar Puli L, Färber K, Harkany T, Schulte G. WNT signaling in activated microglia is proinflammatory. Glia. 59: 119-31. PMID 20967887 DOI: 10.1002/Glia.21081  0.84
2011 Inutan ED, Richards AL, Wager-Miller J, Mackie K, McEwen CN, Trimpin S. Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation Molecular and Cellular Proteomics. 10. PMID 20855542 DOI: 10.1074/Mcp.M110.000760  0.84
2011 Atwood B, MacKie K. Reply by authors to letter from Ashton British Journal of Pharmacology. 163: 1114. DOI: 10.1111/J.1476-5381.2010.01140.X  0.84
2011 Ludányi A, Hu SSJ, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Corrigendum to "Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus". [Neuroscience 174 (2011) 50-63]. Neuroscience. 186: 220. DOI: 10.1016/J.Neuroscience.2011.04.072  0.84
2010 Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CBâ‚‚. Pharmacological Reviews. 62: 588-631. PMID 21079038 DOI: 10.1124/Pr.110.003004  0.84
2010 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC. Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. The European Journal of Neuroscience. 32: 693-706. PMID 21050275 DOI: 10.1111/j.1460-9568.2010.07337.x  0.84
2010 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T. Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13992-4007. PMID 20962221 DOI: 10.1523/Jneurosci.2126-10.2010  0.84
2010 Dmitrieva N, Nagabukuro H, Resuehr D, Zhang G, McAllister SL, McGinty KA, Mackie K, Berkley KJ. Endocannabinoid involvement in endometriosis. Pain. 151: 703-10. PMID 20833475 DOI: 10.1016/J.Pain.2010.08.037  0.84
2010 Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, ... ... Mackie K, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature Neuroscience. 13: 951-7. PMID 20657592 DOI: 10.1038/Nn.2601  0.84
2010 Hu SS, Arnold A, Hutchens JM, Radicke J, Cravatt BF, Wager-Miller J, Mackie K, Straiker A. Architecture of cannabinoid signaling in mouse retina. The Journal of Comparative Neurology. 518: 3848-66. PMID 20653038 DOI: 10.1002/Cne.22429  0.84
2010 Maglóczky Z, Tóth K, Karlócai R, Nagy S, Eross L, Czirják S, Vajda J, Rásonyi G, Kelemen A, Juhos V, Halász P, Mackie K, Freund TF. Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. Epilepsia. 51: 115-20. PMID 20618415 DOI: 10.1111/J.1528-1167.2010.02624.X  0.84
2010 Mukhopadhyay P, Pan H, Rajesh M, Bátkai S, Patel V, Harvey-White J, Mukhopadhyay B, Haskó G, Gao B, Mackie K, Pacher P. CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. British Journal of Pharmacology. 160: 657-68. PMID 20590569 DOI: 10.1111/j.1476-5381.2010.00769.x  0.84
2010 Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. British Journal of Pharmacology. 160: 467-79. PMID 20590558 DOI: 10.1111/J.1476-5381.2010.00729.X  0.84
2010 Alexander SP, Mackie K, Ross RA. Themed issue: cannabinoids. British Journal of Pharmacology. 160: 421-2. PMID 20590554 DOI: 10.1111/j.1476-5381.2010.00831.x  0.84
2010 Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SH, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6273-81. PMID 20445053 DOI: 10.1523/JNEUROSCI.2648-09.2010  0.84
2010 Mukhopadhyay B, Liu J, Osei-Hyiaman D, Godlewski G, Mukhopadhyay P, Wang L, Jeong WI, Gao B, Duester G, Mackie K, Kojima S, Kunos G. Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-γ Journal of Biological Chemistry. 285: 19002-19011. PMID 20410309 DOI: 10.1074/jbc.M109.068460  0.84
2010 Storr MA, Bashashati M, Hirota C, Vemuri VK, Keenan CM, Duncan M, Lutz B, Mackie K, Makriyannis A, Macnaughton WK, Sharkey KA. Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 787-96, e223. PMID 20180825 DOI: 10.1111/J.1365-2982.2010.01478.X  0.84
2010 Atwood BK, Huffman J, Straiker A, Mackie K. JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. British Journal of Pharmacology. 160: 585-93. PMID 20100276 DOI: 10.1111/J.1476-5381.2009.00582.X  0.84
2010 Carvalho AF, Mackie K, Van Bockstaele EJ. Cannabinoid modulation of limbic forebrain noradrenergic circuitry. The European Journal of Neuroscience. 31: 286-301. PMID 20074224 DOI: 10.1111/j.1460-9568.2009.07054.x  0.84
2010 Trimpin S, Herath TN, Inutan ED, Wager-Miller J, Kowalski P, Claude E, Walker JM, Mackie K. Automated solvent-free matrix deposition for tissue imaging by mass spectrometry. Analytical Chemistry. 82: 359-67. PMID 19968249 DOI: 10.1021/Ac902065U  0.84
2010 Mukhopadhyay P, Rajesh M, Bátkai S, Patel V, Kashiwaya Y, Liaudet L, Evgenov OV, Mackie K, Haskó G, Pacher P. CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. Cardiovascular Research. 85: 773-84. PMID 19942623 DOI: 10.1093/cvr/cvp369  0.84
2010 Lipina C, Stretton C, Hastings S, Hundal JS, Mackie K, Irving AJ, Hundal HS. Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells. Diabetes. 59: 375-85. PMID 19933999 DOI: 10.2337/db09-0979  0.84
2010 Scavone JL, Mackie K, Van Bockstaele EJ. Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors. Brain Research. 1312: 18-31. PMID 19931229 DOI: 10.1016/j.brainres.2009.11.023  0.84
2010 Roche M, Johnston P, Mhuircheartaigh ON, Olango WM, Mackie K, Finn DP. Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear. European Journal of Pain (London, England). 14: 487-95. PMID 19786358 DOI: 10.1016/j.ejpain.2009.08.009  0.84
2010 Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SHR, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice (Journal of Neuroscience (2010) (6273-6281)) Journal of Neuroscience. 30.  0.84
2009 Whyte LS, Ryberg E, Sims NA, Ridge SA, Mackie K, Greasley PJ, Ross RA, Rogers MJ. The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 16511-6. PMID 19805329 DOI: 10.1073/pnas.0902743106  0.84
2009 Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, Mackie K. Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Molecular Pharmacology. 76: 1220-7. PMID 19767452 DOI: 10.1124/Mol.109.059030  0.84
2009 Mackie K, Katona I. Get stoned in GABAergic synapses. Nature Neuroscience. 12: 1081-3. PMID 19710646 DOI: 10.1038/Nn0909-1081  0.84
2009 Trimpin S, Herath TN, Inutan ED, Cernat SA, Miller JB, Mackie K, Walker JM. Field-free transmission geometry atmospheric pressure matrix-assisted laser desorption/ionization for rapid analysis of unadulterated tissue samples. Rapid Communications in Mass Spectrometry : Rcm. 23: 3023-7. PMID 19685478 DOI: 10.1002/Rcm.4213  0.84
2009 Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG. Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2699-709. PMID 19675536 DOI: 10.1038/Npp.2009.101  0.84
2009 Straiker A, Mackie K. Cannabinoid signaling in inhibitory autaptic hippocampal neurons. Neuroscience. 163: 190-201. PMID 19501632 DOI: 10.1016/j.neuroscience.2009.06.004  0.84
2009 Kellogg R, Mackie K, Straiker A. Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons. Journal of Neurophysiology. 102: 1160-71. PMID 19494194 DOI: 10.1152/jn.00266.2009  0.84
2009 Nyilas R, Gregg LC, Mackie K, Watanabe M, Zimmer A, Hohmann AG, Katona I. Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. The European Journal of Neuroscience. 29: 1964-78. PMID 19453631 DOI: 10.1111/J.1460-9568.2009.06751.X  0.84
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131  0.84
2009 Sun X, Wang H, Okabe M, Mackie K, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK. Genetic loss of Faah compromises male fertility in mice. Biology of Reproduction. 80: 235-42. PMID 18987328 DOI: 10.1095/Biolreprod.108.072736  0.84
2008 Harkany T, Mackie K, Doherty P. Wiring and firing neuronal networks: endocannabinoids take center stage. Current Opinion in Neurobiology. 18: 338-45. PMID 18801434 DOI: 10.1016/J.Conb.2008.08.007  0.84
2008 Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu HC, et al. Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proceedings of the National Academy of Sciences of the United States of America. 105: 8760-5. PMID 18562289 DOI: 10.1073/Pnas.0803545105  0.84
2008 Suárez J, Bermúdez-Silva FJ, Mackie K, Ledent C, Zimmer A, Cravatt BF, de Fonseca FR. Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei. The Journal of Comparative Neurology. 509: 400-21. PMID 18521853 DOI: 10.1002/Cne.21774  0.84
2008 Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3024-34. PMID 18492727 DOI: 10.1096/Fj.07-101865  0.84
2008 Duncan M, Mouihate A, Mackie K, Keenan CM, Buckley NE, Davison JS, Patel KD, Pittman QJ, Sharkey KA. Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G78-G87. PMID 18483180 DOI: 10.1152/Ajpgi.90285.2008  0.84
2008 Mackie K. Cannabinoid Receptors: Where They are and What They do Journal of Neuroendocrinology. 20: 10-14. PMID 18426493 DOI: 10.1111/J.1365-2826.2008.01671.X  0.48
2008 Cinar R, Freund TF, Katona I, Mackie K, Szucs M. Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes. Neurochemistry International. 52: 1402-9. PMID 18407377 DOI: 10.1016/J.Neuint.2008.02.005  0.84
2008 Daigle TL, Kwok ML, Mackie K. Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism. Journal of Neurochemistry. 106: 70-82. PMID 18331587 DOI: 10.1111/j.1471-4159.2008.05336.x  0.84
2008 Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K. GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proceedings of the National Academy of Sciences of the United States of America. 105: 2699-704. PMID 18263732 DOI: 10.1073/Pnas.0711278105  0.84
2008 Nyilas R, Dudok B, Urbán GM, Mackie K, Watanabe M, Cravatt BF, Freund TF, Katona I. Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1058-63. PMID 18234884 DOI: 10.1523/Jneurosci.5102-07.2008  0.84
2008 Malone DT, Kearn CS, Chongue L, Mackie K, Taylor DA. Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience. 152: 265-72. PMID 18082330 DOI: 10.1016/j.neuroscience.2007.10.043  0.84
2008 Rimmerman N, Hughes HV, Bradshaw HB, Pazos MX, Mackie K, Prieto AL, Walker JM. Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. British Journal of Pharmacology. 153: 380-9. PMID 17965731 DOI: 10.1038/Sj.Bjp.0707561  0.84
2008 Daigle TL, Kearn CS, Mackie K. Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling. Neuropharmacology. 54: 36-44. PMID 17681354 DOI: 10.1016/j.neuropharm.2007.06.005  0.84
2008 Mátyás F, Urbán GM, Watanabe M, Mackie K, Zimmer A, Freund TF, Katona I. Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area. Neuropharmacology. 54: 95-107. PMID 17655884 DOI: 10.1016/J.Neuropharm.2007.05.028  0.84
2008 Mackie K, Ross RA. CB 2 cannabinoid receptors: New vistas British Journal of Pharmacology. 153: 177-178. DOI: 10.1038/sj.bjp.0707617  0.84
2007 Cachope R, Mackie K, Triller A, O'Brien J, Pereda AE. Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron. 56: 1034-47. PMID 18093525 DOI: 10.1016/J.Neuron.2007.11.014  0.84
2007 Mackie K. From active ingredients to the discovery of the targets: the cannabinoid receptors. Chemistry & Biodiversity. 4: 1693-1706. PMID 17712815 DOI: 10.1002/Cbdv.200790148  0.44
2007 Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Molecular Pharmacology. 72: 612-21. PMID 17584991 DOI: 10.1124/Mol.107.037796  0.84
2007 Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, et al. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nature Neuroscience. 10: 870-9. PMID 17558404 DOI: 10.1038/Nn1916  0.84
2007 Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, ... Mackie K, et al. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (New York, N.Y.). 316: 1212-6. PMID 17525344 DOI: 10.1126/Science.1137406  0.84
2007 Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. A molecular basis of analgesic tolerance to cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4165-77. PMID 17428994 DOI: 10.1523/Jneurosci.5648-06.2007  0.84
2007 Mitrirattanakul S, López-Valdés HE, Liang J, Matsuka Y, Mackie K, Faull KF, Spigelman I. Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence. Alcoholism, Clinical and Experimental Research. 31: 855-67. PMID 17386072 DOI: 10.1111/J.1530-0277.2007.00366.X  0.84
2007 Harkany T, Guzmán M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K. The emerging functions of endocannabinoid signaling during CNS development. Trends in Pharmacological Sciences. 28: 83-92. PMID 17222464 DOI: 10.1016/J.Tips.2006.12.004  0.84
2007 Duarte JM, Nogueira C, Mackie K, Oliveira CR, Cunha RA, Köfalvi A. Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats. Experimental Neurology. 204: 479-84. PMID 17222407 DOI: 10.1016/j.expneurol.2006.11.013  0.84
2007 Deshmukh S, Onozuka K, Bender KJ, Bender VA, Lutz B, Mackie K, Feldman DE. Postnatal development of cannabinoid receptor type 1 expression in rodent somatosensory cortex. Neuroscience. 145: 279-87. PMID 17210229 DOI: 10.1016/J.Neuroscience.2006.11.033  0.84
2007 Chen K, Neu A, Howard AL, Földy C, Echegoyen J, Hilgenberg L, Smith M, Mackie K, Soltesz I. Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 46-58. PMID 17202471 DOI: 10.1523/Jneurosci.3966-06.2007  0.84
2007 Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K, Piomelli D. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. The Journal of Biological Chemistry. 282: 1518-28. PMID 17121838 DOI: 10.1074/Jbc.M607809200  0.84
2007 Oropeza VC, Mackie K, Van Bockstaele EJ. Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex. Brain Research. 1127: 36-44. PMID 17113043 DOI: 10.1016/j.brainres.2006.09.110  0.84
2007 Straiker A, Mackie K. Metabotropic suppression of excitation in murine autaptic hippocampal neurons. The Journal of Physiology. 578: 773-85. PMID 17110416 DOI: 10.1113/jphysiol.2006.117499  0.84
2006 Monory K, Massa F, Egertová M, Eder M, Blaudzun H, Westenbroek R, Kelsch W, Jacob W, Marsch R, Ekker M, Long J, Rubenstein JL, Goebbels S, Nave KA, During M, ... ... Mackie K, et al. The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron. 51: 455-66. PMID 16908411 DOI: 10.1016/J.Neuron.2006.07.006  0.84
2006 Mitrirattanakul S, Ramakul N, Guerrero AV, Matsuka Y, Ono T, Iwase H, Mackie K, Faull KF, Spigelman I. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain. 126: 102-14. PMID 16844297 DOI: 10.1016/J.Pain.2006.06.016  0.84
2006 Schuchmann S, Schmitz D, Rivera C, Vanhatalo S, Salmen B, Mackie K, Sipilä ST, Voipio J, Kaila K. Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nature Medicine. 12: 817-23. PMID 16819552 DOI: 10.1038/Nm1422  0.84
2006 Mackie K, Stella N. Cannabinoid receptors and endocannabinoids: evidence for new players. The Aaps Journal. 8: E298-306. PMID 16796380 DOI: 10.1208/aapsj080234  0.84
2006 Straiker A, Mackie K. Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 years. The Aaps Journal. 8: E272-6. PMID 16796377 DOI: 10.1208/aapsj080231  0.84
2006 Tam J, Ofek O, Fride E, Ledent C, Gabet Y, M̈uller R, Zimmer A, Mackie K, Mechoulam R, Shohami E, Bab I. Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling Molecular Pharmacology. 70: 786-792. PMID 16772520 DOI: 10.1124/Mol.106.026435  0.84
2006 Katona I, Urbán GM, Wallace M, Ledent C, Jung KM, Piomelli D, Mackie K, Freund TF. Molecular composition of the endocannabinoid system at glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5628-37. PMID 16723519 DOI: 10.1523/Jneurosci.0309-06.2006  0.84
2006 Pickel VM, Chan J, Kearn CS, Mackie K. Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens. The Journal of Comparative Neurology. 495: 299-313. PMID 16440297 DOI: 10.1002/cne.20881  0.84
2006 Mackie K. Cannabinoid receptors as therapeutic targets. Annual Review of Pharmacology and Toxicology. 46: 101-122. PMID 16402900 DOI: 10.1146/Annurev.Pharmtox.46.120604.141254  0.32
2006 Mátyás F, Yanovsky Y, Mackie K, Kelsch W, Misgeld U, Freund TF. Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia. Neuroscience. 137: 337-61. PMID 16289348 DOI: 10.1016/J.Neuroscience.2005.09.005  0.84
2005 Lauckner JE, Hille B, Mackie K. The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 19144-9. PMID 16365309 DOI: 10.1073/pnas.0509588102  0.84
2005 Berghuis P, Dobszay MB, Wang X, Spano S, Ledda F, Sousa KM, Schulte G, Ernfors P, Mackie K, Paratcha G, Hurd YL, Harkany T. Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 19115-20. PMID 16357196 DOI: 10.1073/Pnas.0509494102  0.84
2005 Nyíri G, Cserép C, Szabadits E, Mackie K, Freund TF. CB1 cannabinoid receptors are enriched in the perisynaptic annulus and on preterminal segments of hippocampal GABAergic axons. Neuroscience. 136: 811-22. PMID 16344153 DOI: 10.1016/j.neuroscience.2005.01.026  0.84
2005 Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (New York, N.Y.). 310: 329-32. PMID 16224028 DOI: 10.1126/Science.1115740  0.84
2005 Straiker A, Mackie K. Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. The Journal of Physiology. 569: 501-17. PMID 16179366 DOI: 10.1113/jphysiol.2005.091918  0.84
2005 Osei-Hyiaman D, Depetrillo M, Harvey-White J, Bannon AW, Cravatt BF, Kuhar MJ, Mackie K, Palkovits M, Kunos G. Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology. 81: 273-82. PMID 16131814 DOI: 10.1159/000087925  0.84
2005 Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K, Hille B. Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. The Journal of General Physiology. 126: 243-62. PMID 16129772 DOI: 10.1085/Jgp.200509309  0.84
2005 Jung KM, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, Mackie K, Piomelli D. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Molecular Pharmacology. 68: 1196-202. PMID 16051747 DOI: 10.1124/Mol.105.013961  0.84
2005 Bodor AL, Katona I, Nyíri G, Mackie K, Ledent C, Hájos N, Freund TF. Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6845-56. PMID 16033894 DOI: 10.1523/Jneurosci.0442-05.2005  0.84
2005 Mackie K. Cannabinoid receptor homo- and heterodimerization. Life Sciences. 77: 1667-1673. PMID 15978631 DOI: 10.1016/J.Lfs.2005.05.011  0.36
2005 Nyíri G, Szabadits E, Cserép C, Mackie K, Shigemoto R, Freund TF. GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons. The European Journal of Neuroscience. 21: 3034-42. PMID 15978014 DOI: 10.1111/j.1460-9568.2005.04146.x  0.84
2005 Benito C, Kim WK, Kim WK, Chavarría I, Hillard CJ, Mackie K, Tolón RM, Williams K, Williams K, Romero J. A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2530-6. PMID 15758162 DOI: 10.1523/JNEUROSCI.3923-04.2005  0.84
2005 Kearn CS, Blake-Palmer K, Daniel E, Mackie K, Glass M. Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Molecular Pharmacology. 67: 1697-704. PMID 15710746 DOI: 10.1124/mol.104.006882  0.84
2004 Bátkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J, Offertáler L, Mackie K, Rudd MA, Bukoski RD, Kunos G. Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation. 110: 1996-2002. PMID 15451779 DOI: 10.1161/01.Cir.0000143230.23252.D2  0.44
2004 Hirasawa M, Schwab Y, Natah S, Hillard CJ, Mackie K, Sharkey KA, Pittman QJ. Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain. The Journal of Physiology. 559: 611-24. PMID 15254151 DOI: 10.1113/Jphysiol.2004.066159  0.84
2004 Pickel VM, Chan J, Kash TL, Rodríguez JJ, MacKie K. Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens. Neuroscience. 127: 101-12. PMID 15219673 DOI: 10.1016/j.neuroscience.2004.05.015  0.84
2004 Suh BC, Horowitz LF, Hirdes W, Mackie K, Hille B. Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq. The Journal of General Physiology. 123: 663-83. PMID 15173220 DOI: 10.1085/jgp.200409029  0.84
2004 Harkany T, Holmgren C, Härtig W, Qureshi T, Chaudhry FA, Storm-Mathisen J, Dobszay MB, Berghuis P, Schulte G, Sousa KM, Fremeau RT, Edwards RH, Mackie K, Ernfors P, Zilberter Y. Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4978-88. PMID 15163690 DOI: 10.1523/Jneurosci.4884-03.2004  0.84
2004 Luk T, Jin W, Zvonok A, Lu D, Lin XZ, Chavkin C, Makriyannis A, Mackie K. Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist. British Journal of Pharmacology. 142: 495-500. PMID 15148260 DOI: 10.1038/Sj.Bjp.0705792  0.84
2004 MacNaughton WK, Van Sickle MD, Keenan CM, Cushing K, Mackie K, Sharkey KA. Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G863-71. PMID 14701723 DOI: 10.1152/Ajpgi.00482.2003  0.84
2003 Harkany T, Härtig W, Berghuis P, Dobszay MB, Zilberter Y, Edwards RH, Mackie K, Ernfors P. Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons. The European Journal of Neuroscience. 18: 1979-92. PMID 14622230 DOI: 10.1046/J.1460-9568.2003.02898.X  0.84
2003 Chen K, Ratzliff A, Hilgenberg L, Gulyás A, Freund TF, Smith M, Dinh TP, Piomelli D, Mackie K, Soltesz I. Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron. 39: 599-611. PMID 12925275 DOI: 10.1016/S0896-6273(03)00499-9  0.84
2003 McLaughlin JP, Xu M, Mackie K, Chavkin C. Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization. The Journal of Biological Chemistry. 278: 34631-40. PMID 12815037 DOI: 10.1074/Jbc.M304022200  0.84
2003 Van Sickle MD, Oland LD, Mackie K, Davison JS, Sharkey KA. Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G566-76. PMID 12791597 DOI: 10.1152/Ajpgi.00113.2003  0.84
2003 Walter L, Franklin A, Witting A, Wade C, Xie Y, Kunos G, Mackie K, Stella N. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1398-405. PMID 12598628  0.84
2003 Walter L, Franklin A, Witting A, Wade C, Xie Y, Kunos G, Mackie K, Stella N. Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration The Journal of Neuroscience. 23: 1398-1405. DOI: 10.1523/Jneurosci.23-04-01398.2003  0.8
2002 Wager-Miller J, Westenbroek R, Mackie K. Dimerization of G protein-coupled receptors: CB1 cannabinoid receptors as an example. Chemistry and Physics of Lipids. 121: 83-89. PMID 12505693 DOI: 10.1016/S0009-3084(02)00151-2  0.76
2002 Roche JP, Westenbroek R, Sorom AJ, Hille B, Mackie K, Shapiro MS. Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels. British Journal of Pharmacology. 137: 1173-86. PMID 12466226 DOI: 10.1038/sj.bjp.0704989  0.84
2002 Brown SM, Wager-Miller J, Mackie K. Cloning and molecular characterization of the rat CB2 cannabinoid receptor. Biochimica Et Biophysica Acta. 1576: 255-264. PMID 12084572 DOI: 10.1016/S0167-4781(02)00341-X  0.76
2002 Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/Pr.54.2.161  0.84
2002 Diana MA, Levenes C, Mackie K, Marty A. Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 200-8. PMID 11756503  0.84
2002 Hsieh C, Brown S, Derleth C, Mackie K. Internalization and Recycling of the CB1 Cannabinoid Receptor Journal of Neurochemistry. 73: 493-501. PMID 10428044 DOI: 10.1046/J.1471-4159.1999.0730493.X  0.64
2001 Katona I, Rancz EA, Acsady L, Ledent C, Mackie K, Hajos N, Freund TF. Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9506-18. PMID 11717385 DOI: 10.1523/Jneurosci.21-23-09506.2001  0.84
2001 Van Sickle MD, Oland LD, Ho W, Hillard CJ, Mackie K, Davison JS, Sharkey KA. Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. Gastroenterology. 121: 767-74. PMID 11606489 DOI: 10.1053/Gast.2001.28466  0.84
2001 Rodriguez JJ, Mackie K, Pickel VM. Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 823-33. PMID 11157068 DOI: 10.1523/Jneurosci.21-03-00823.2001  0.84
2000 Calignano A, Kátona I, Désarnaud F, Giuffrida A, La Rana G, Mackie K, Freund TF, Piomelli D. Bidirectional control of airway responsiveness by endogenous cannabinoids. Nature. 408: 96-101. PMID 11081515 DOI: 10.1038/35040576  0.84
2000 Katona I, Sperlágh B, Maglóczky Z, Sántha E, Köfalvi A, Czirják S, Mackie K, Vizi ES, Freund TF. GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus. Neuroscience. 100: 797-804. PMID 11036213 DOI: 10.1016/S0306-4522(00)00286-4  0.84
2000 Hájos N, Katona I, Naiem SS, MacKie K, Ledent C, Mody I, Freund TF. Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. The European Journal of Neuroscience. 12: 3239-49. PMID 10998107 DOI: 10.1046/J.1460-9568.2000.00217.X  0.84
2000 Irving AJ, Coutts AA, Harvey J, Rae MG, Mackie K, Bewick GS, Pertwee RG. Functional expression of cell surface cannabinoid CB(1) receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons. Neuroscience. 98: 253-62. PMID 10854756 DOI: 10.1016/S0306-4522(00)00120-2  0.84
2000 Shapiro MS, Roche JP, Kaftan EJ, Cruzblanca H, Mackie K, Hille B. Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1710-21. PMID 10684873 DOI: 10.1523/Jneurosci.20-05-01710.2000  0.84
2000 Sañudo-Peña MC, Tsou K, Romero J, Mackie K, Walker JM. Role of the superior colliculus in the motor effects of cannabinoids and dopamine. Brain Research. 853: 207-14. PMID 10640618 DOI: 10.1016/S0006-8993(99)02291-X  0.84
1999 Straiker A, Stella N, Piomelli D, Mackie K, Karten HJ, Maguire G. Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proceedings of the National Academy of Sciences of the United States of America. 96: 14565-70. PMID 10588745 DOI: 10.1073/Pnas.96.25.14565  0.84
1999 Tsou K, Mackie K, Sañudo-Peña MC, Walker JM. Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation. Neuroscience. 93: 969-75. PMID 10473261 DOI: 10.1016/S0306-4522(99)00086-X  0.84
1999 Roche JP, Bounds S, Brown S, Mackie K. A mutation in the second transmembrane region of the CB1 receptor selectively disrupts G protein signaling and prevents receptor internalization Molecular Pharmacology. 56: 611-618. PMID 10462549 DOI: 10.1124/Mol.56.3.611  0.84
1999 Mackie K, Walker JM. Kang tsou (1932-1999) Trends in Neurosciences. 22: 331. PMID 10407414 DOI: 10.1016/S0166-2236(99)01450-2  0.64
1999 Katona I, Sperlágh B, Sík A, Käfalvi A, Vizi ES, Mackie K, Freund TF. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4544-58. PMID 10341254 DOI: 10.1523/Jneurosci.19-11-04544.1999  0.84
1999 Jin W, Brown S, Roche JP, Hsieh C, Celver JP, Kovoor A, Chavkin C, Mackie K. Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3773-80. PMID 10234009 DOI: 10.1523/Jneurosci.19-10-03773.1999  0.84
1998 García DE, Li B, García-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca2+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9163-70. PMID 9801356  0.84
1998 Garcia DE, Brown S, Hille B, Mackie K. Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2834-41. PMID 9526000 DOI: 10.1523/Jneurosci.18-08-02834.1998  0.84
1998 Tsou K, Brown S, Sañudo-Peña MC, Mackie K, Walker JM. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience. 83: 393-411. PMID 9460749 DOI: 10.1016/S0306-4522(97)00436-3  0.84
1998 Felder CC, Joyce KE, Briley EM, Glass M, Mackie KP, Fahey KJ, Cullinan GJ, Hunden DC, Johnson DW, Chaney MO, Koppel GA, Brownstein M. LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation. The Journal of Pharmacology and Experimental Therapeutics. 284: 291-7. PMID 9435190  0.84
1998 Garcı́a DE, Li B, Garcı́a-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-Protein β-Subunit Specificity in the Fast Membrane-Delimited Inhibition of Ca2+ Channels The Journal of Neuroscience. 18: 9163-9170. DOI: 10.1523/Jneurosci.18-22-09163.1998  0.72
1997 Twitchell W, Brown S, Mackie K. Cannabinoids Inhibit N- and P/Q-Type Calcium Channels in Cultured Rat Hippocampal Neurons Journal of Neurophysiology. 78: 43-50. PMID 9242259 DOI: 10.1152/Jn.1997.78.1.43  0.64
1997 Baguley WA, Hay WT, Mackie KP, Cheney FW, Cullen BF. Cardiac dysrhythmias associated with the intravenous administration of ondansetron and metoclopramide. Anesthesia and Analgesia. 84: 1380-1. PMID 9174325 DOI: 10.1097/00000539-199706000-00038  0.84
1996 Herlitze S, Garcia DE, Mackie K, Hille B, Scheuer T, Catterall WA. Modulation of Ca2+ channels by G-protein beta gamma subunits. Nature. 380: 258-62. PMID 8637576 DOI: 10.1038/380258a0  0.36
1993 Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60. PMID 8395053 DOI: 10.1073/Pnas.90.16.7656  0.84
1992 Mackie K, Hille B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 3825-9. PMID 1315042 DOI: 10.1073/Pnas.89.9.3825  0.76
1989 Mackie KP, Nairn AC, Hampel G, Lam G, Jaffe EA. Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells. The Journal of Biological Chemistry. 264: 1748-53. PMID 2536373  0.84
1983 Cserr HF, Bradbury MW, Mackie K, Moody EJ. Control of extracellular ions in skate brain during osmotic disturbances. The American Journal of Physiology. 245: R853-9. PMID 6660332 DOI: 10.1152/Ajpregu.1983.245.6.R853  0.84
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