Year |
Citation |
Score |
2021 |
Tortoriello G, Beiersdorf J, Romani S, Williams G, Cameron GA, Mackie K, Williams MJ, Di Marzo V, Keimpema E, Doherty P, Harkany T. Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in . Cannabis and Cannabinoid Research. 6: 119-136. PMID 33912677 DOI: 10.1089/can.2020.0010 |
0.363 |
|
2021 |
Kolbe MR, Hohmann T, Hohmann U, Ghadban C, Mackie K, Zöller C, Prell J, Illert J, Strauss C, Dehghani F. THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner. Cancers. 13. PMID 33802282 DOI: 10.3390/cancers13051064 |
0.366 |
|
2021 |
Cottone E, Pomatto V, Rapelli S, Scandiffio R, Mackie K, Bovolin P. Cannabinoid Receptor Modulation of Neurogenesis: ST14A Striatal Neural Progenitor Cells as a Simplified In Vitro Model. Molecules (Basel, Switzerland). 26. PMID 33800024 DOI: 10.3390/molecules26051448 |
0.326 |
|
2021 |
Dvorakova M, Kubik-Zahorodna A, Straiker A, Sedlacek R, Hajkova A, Mackie K, Blahos J. SGIP1 is involved in regulation of emotionality, mood, and nociception and tunes in vivo signaling of Cannabinoid Receptor 1. British Journal of Pharmacology. PMID 33491188 DOI: 10.1111/bph.15383 |
0.801 |
|
2020 |
Lu HC, Mackie K. Review of the Endocannabinoid System. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 32980261 DOI: 10.1016/j.bpsc.2020.07.016 |
0.418 |
|
2020 |
Iyer V, Slivicki RA, Thomaz AC, Crystal JD, Mackie K, Hohmann AG. The cannabinoid CB receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence. European Journal of Pharmacology. 886: 173544. PMID 32896549 DOI: 10.1016/J.Ejphar.2020.173544 |
0.314 |
|
2020 |
Martinez LR, Black KC, Webb BT, Bell A, Baygani SK, Mier TJ, Dominguez L, Mackie K, Kalinovsky A. Components of Endocannabinoid Signaling System are Expressed in the Perinatal Mouse Cerebellum and Required for its Normal Development. Eneuro. PMID 32179579 DOI: 10.1523/ENEURO.0471-19.2020 |
0.355 |
|
2020 |
Farkas E, Varga E, Kovács B, Szilvásy-Szabó A, Cote-Vélez A, Péterfi Z, Matziari M, Tóth M, Zelena D, Mezriczky Z, Kádár A, Kővári D, Watanabe M, Kano M, Mackie K, et al. A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System. Iscience. 23: 100921. PMID 32143135 DOI: 10.1016/J.Isci.2020.100921 |
0.344 |
|
2020 |
Marcus DJ, Bedse G, Gaulden AD, Ryan JD, Kondev V, Winters ND, Rosas-Vidal LE, Altemus M, Mackie K, Lee FS, Delpire E, Patel S. Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening. Neuron. PMID 31948734 DOI: 10.1016/J.Neuron.2019.12.024 |
0.317 |
|
2019 |
Zuccarini G, D’Atri I, Cottone E, Mackie K, Shainer I, Gothilf Y, Provero P, Bovolin P, Merlo GR. Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos. International Journal of Molecular Sciences. 21: 168. PMID 31881740 DOI: 10.3390/Ijms21010168 |
0.402 |
|
2019 |
Henderson-Redmond AN, Nealon CM, Davis BJ, Yuill MB, Sepulveda DE, Blanton H, Piscura MK, Zee ML, Haskins CP, Marcus DJ, Mackie K, Guindon J, Morgan DJ. c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner. Neuropharmacology. 107847. PMID 31758947 DOI: 10.1016/j.neuropharm.2019.107847 |
0.51 |
|
2019 |
Garai S, Kulkarni PM, Schaffer PC, Leo L, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, ... ... Mackie K, et al. Application of Fluorine- And Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of CB1 Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31756109 DOI: 10.1021/Acs.Jmedchem.9B01142 |
0.794 |
|
2019 |
Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, ... Mackie K, et al. Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy. Molecular Psychiatry. PMID 31735910 DOI: 10.1038/S41380-019-0580-4 |
0.366 |
|
2019 |
Jacobs IR, Xu C, Hermes DJ, League AF, Xu C, Nath B, Jiang W, Niphakis MJ, Cravatt BF, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Inhibitory Control Deficits Associated with Upregulation of CBR in the HIV-1 Tat Transgenic Mouse Model of Hand. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 31372820 DOI: 10.1007/S11481-019-09867-W |
0.318 |
|
2019 |
Pickel VM, Bourie F, Chan J, Mackie K, Lane D, Wang G. Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31323660 DOI: 10.1038/s41386-019-0466-9 |
0.386 |
|
2019 |
Wang ZJ, Hu SS, Bradshaw HB, Sun L, Mackie K, Straiker A, Heinbockel T. Cannabinoid Receptor-Mediated Modulation of Inhibitory Inputs to Mitral Cells in the Main Olfactory Bulb. Journal of Neurophysiology. PMID 31215302 DOI: 10.1152/Jn.00100.2018 |
0.812 |
|
2019 |
Leishman E, Mackie K, Bradshaw HB. Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. Frontiers in Molecular Neuroscience. 12: 142. PMID 31213981 DOI: 10.3389/fnmol.2019.00142 |
0.304 |
|
2019 |
Urquhart MA, Ross JA, Reyes BAS, Nitikman M, Thomas SA, Mackie K, Van Bockstaele EJ. Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex. Neurobiology of Stress. 10: 100164. PMID 31193575 DOI: 10.1016/j.ynstr.2019.100164 |
0.319 |
|
2019 |
Smoker MP, Mackie K, Lapish CC, Boehm SL. Self-administration of edible Δ-tetrahydrocannabinol and associated behavioral effects in mice. Drug and Alcohol Dependence. 199: 106-115. PMID 31029878 DOI: 10.1016/J.Drugalcdep.2019.02.020 |
0.303 |
|
2019 |
Fitzgerald ML, Mackie K, Pickel VM. Ultrastructural localization of cannabinoid-1 (CB1) and mGluR5 receptors in the prefrontal cortex and amygdala. The Journal of Comparative Neurology. PMID 31008528 DOI: 10.1002/Cne.24704 |
0.4 |
|
2019 |
Murataeva N, Daily L, Taylor X, Dhopeshwarkar A, Hu SS, Miller S, McHugh D, Oehler O, Li S, Bonanno JA, Mackie K, Straiker A. Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea. Cornea. PMID 30969262 DOI: 10.1097/Ico.0000000000001934 |
0.794 |
|
2019 |
Grabiec U, Hohmann T, Ghadban C, Rothgänger C, Wong D, Antonietti A, Groth T, Mackie K, Dehghani F. Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures. International Journal of Molecular Sciences. 20. PMID 30871175 DOI: 10.3390/ijms20061266 |
0.48 |
|
2019 |
Korchynska S, Lutz MI, Borók E, Pammer J, Cinquina V, Fedirko N, Irving AJ, Mackie K, Harkany T, Keimpema E. GPR55 controls functional differentiation of self-renewing epithelial progenitors for salivation. Jci Insight. 4. PMID 30830860 DOI: 10.1172/Jci.Insight.122947 |
0.358 |
|
2019 |
Hawken ER, Normandeau CP, Gardner Gregory J, Cécyre B, Bouchard JF, Mackie K, Dumont ÉC. A novel GPR55-mediated satiety signal in the oval Bed Nucleus of the Stria Terminalis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30647449 DOI: 10.1038/S41386-018-0309-0 |
0.342 |
|
2019 |
Mackie K, Ford C, Stella N. Decision letter: Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion Elife. DOI: 10.7554/Elife.47209.021 |
0.373 |
|
2019 |
Abood M, Alexander SP, Barth F, Bonner TI, Bradshaw H, Cabral G, Casellas P, Cravatt BF, Devane WA, Di Marzo V, Elphick MR, Felder CC, Greasley P, Herkenham M, Howlett AC, ... ... Mackie K, et al. Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f13/2019.4 |
0.379 |
|
2018 |
Leishman E, Murphy MN, Murphy MI, Mackie K, Bradshaw HB. Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains. Frontiers in Molecular Neuroscience. 11: 436. PMID 30542263 DOI: 10.3389/fnmol.2018.00436 |
0.32 |
|
2018 |
Li AL, Lin X, Dhopeshwarkar AS, Thomaz AC, Carey LM, Liu Y, Nikas SP, Makriyannis A, Mackie K, Hohmann AG. The cannabinoid CB2 agonist AM1710 differentially suppresses distinct pathological pain states and attenuates morphine tolerance and withdrawal. Molecular Pharmacology. PMID 30504240 DOI: 10.1124/Mol.118.113233 |
0.395 |
|
2018 |
Chen YH, Lee HJ, Lee MT, Wu YT, Lee YH, Hwang LL, Hung MS, Zimmer A, Mackie K, Chiou LC. Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348772 DOI: 10.1073/pnas.1807991115 |
0.371 |
|
2018 |
Bara A, Manduca A, Bernabeu A, Borsoi M, Serviado M, Lassalle O, Murphy MN, Wager-Miller J, Mackie K, Pelissier-Alicot AL, Trezza V, Manzoni OJ. Sex-dependent effects of in utero cannabinoid exposure on cortical function. Elife. 7. PMID 30201092 DOI: 10.7554/Elife.36234 |
0.335 |
|
2018 |
Liu Y, Ji L, Eno M, Kudalkar S, Li A, Schimpgen M, Benchama O, Morales P, Xu S, Hurst DP, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis D, ... ... Mackie K, et al. (R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. Journal of Medicinal Chemistry. PMID 30196704 DOI: 10.1021/Acs.Jmedchem.8B00611 |
0.313 |
|
2018 |
Hermes DJ, Xu C, Poklis JL, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology. PMID 30114402 DOI: 10.1016/J.Neuropharm.2018.08.013 |
0.443 |
|
2018 |
Mulpuri Y, Marty VN, Munier JJ, Mackie K, Schmidt BL, Seltzman HH, Spigelman I. Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. Neuropharmacology. PMID 29981335 DOI: 10.1016/J.Neuropharm.2018.07.002 |
0.348 |
|
2018 |
Migliaccio M, Ricci G, Suglia A, Manfrevola F, Mackie K, Fasano S, Pierantoni R, Chioccarelli T, Cobellis G. Analysis of Endocannabinoid System in Rat Testis During the First Spermatogenetic Wave. Frontiers in Endocrinology. 9: 269. PMID 29896156 DOI: 10.3389/Fendo.2018.00269 |
0.439 |
|
2018 |
Miller S, Kulkarni S, Ciesielski A, Nikas SP, Mackie K, Makriyannis A, Straiker A. Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure. Pharmaceuticals (Basel, Switzerland). 11. PMID 29786643 DOI: 10.3390/Ph11020050 |
0.81 |
|
2018 |
Straiker A, Dvorakova M, Zimmowitch A, Mackie KP. Cannabidiol inhibits endocannabinoid signaling in autaptic hippocampal neurons. Molecular Pharmacology. PMID 29669714 DOI: 10.1124/mol.118.111864 |
0.83 |
|
2018 |
Leishman E, Murphy M, Mackie K, Bradshaw HB. Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult. Biochimica Et Biophysica Acta. 1863: 479-492. PMID 29408467 DOI: 10.1016/j.bbalip.2018.02.001 |
0.302 |
|
2017 |
Shonesy BC, Parrish WP, Haddad HK, Stephenson JR, Báldi R, Bluett RJ, Marks CR, Centanni SW, Folkes OM, Spiess K, Augustin SM, Mackie K, Lovinger DM, Winder DG, Patel S, et al. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biological Psychiatry. PMID 29458998 DOI: 10.1016/J.Biopsych.2017.11.036 |
0.534 |
|
2017 |
Sumida H, Lu E, Chen H, Yang Q, Mackie K, Cyster JG. GPR55 regulates intraepithelial lymphocyte migration dynamics and susceptibility to intestinal damage. Science Immunology. 2. PMID 29222090 DOI: 10.1126/Sciimmunol.Aao1135 |
0.393 |
|
2017 |
Sepers MD, Smith-Dijak A, LeDue J, Kolodziejczyk K, Mackie K, Raymond LA. Endocannabinoid-specific impairment in synaptic plasticity in striatum of Huntington's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29192125 DOI: 10.1523/JNEUROSCI.1739-17.2017 |
0.361 |
|
2017 |
Lin X, Dhopeshwarkar AS, Huibregtse M, Mackie K, Hohmann AG. The slowly signaling G protein-biased CB2 cannabinoid receptor agonist LY2828360 suppresses neuropathic pain with sustained efficacy and attenuates morphine tolerance and dependence. Molecular Pharmacology. PMID 29192123 DOI: 10.1124/Mol.117.109355 |
0.319 |
|
2017 |
Westphal M, Schafroth MA, Sarott R, Imhof M, Bold C, Leippe P, Dhopeshwarkar A, Grandner J, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA. Synthesis of Photoswitchable Δ(9)-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. Journal of the American Chemical Society. PMID 29161035 DOI: 10.1021/Jacs.7B06456 |
0.466 |
|
2017 |
Mitjavila J, Yin D, Kulkarni PM, Zanato C, Thakur GA, Ross R, Greig I, Mackie K, Straiker A. Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons. Pharmacological Research. PMID 29158048 DOI: 10.1016/j.phrs.2017.11.019 |
0.82 |
|
2017 |
Jourdan T, Park JK, Varga ZV, Pálóczi J, Coffey NJ, Rosenberg AZ, Godlewski G, Cinar R, Mackie K, Pacher P, Kunos G. Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy. Diabetes, Obesity & Metabolism. PMID 29106063 DOI: 10.1111/Dom.13150 |
0.344 |
|
2017 |
Slivicki RA, Xu Z, Kulkarni PM, Pertwee RG, Mackie K, Thakur GA, Hohmann AG. Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence. Biological Psychiatry. PMID 28823711 DOI: 10.1016/J.Biopsych.2017.06.032 |
0.401 |
|
2017 |
Xu C, Hermes DJ, Nwanguma B, Jacobs IR, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska B, Fitting S. Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Molecular and Cellular Neurosciences. PMID 28733129 DOI: 10.1016/J.Mcn.2017.07.003 |
0.383 |
|
2017 |
Ruehle S, Wager-Miller J, Straiker A, Farnsworth J, Murphy MN, Loch S, Monory K, Mackie K, Lutz B. Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse. Journal of Neurochemistry. PMID 28608535 DOI: 10.1111/jnc.14099 |
0.822 |
|
2017 |
Miller S, Hu SS, Leishman E, Morgan D, Wager-Miller J, Mackie K, Bradshaw HB, Straiker A. A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner. Investigative Ophthalmology & Visual Science. 58: 2930-2938. PMID 28593245 DOI: 10.1167/iovs.16-21330 |
0.79 |
|
2017 |
Li AL, Carey LM, Mackie K, Hohmann AG. The cannabinoid CB2 agonist GW405833 suppresses inflammatory and neuropathic pain through a CB1 mechanism that is independent of CB2 receptors in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 28592614 DOI: 10.1124/Jpet.117.241901 |
0.381 |
|
2017 |
Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. PMID 28527758 DOI: 10.1016/J.Neuropharm.2017.05.018 |
0.608 |
|
2017 |
Zhong H, Tong L, Gu N, Gao F, Lu Y, Xie RG, Liu J, Li X, Bergeron R, Pomeranz LE, Mackie K, Wang F, Luo CX, Ren Y, Wu SX, et al. Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. The Journal of Clinical Investigation. PMID 28463228 DOI: 10.1172/JCI91038 |
0.377 |
|
2017 |
Carey LM, Gutierrez T, Deng L, Lee WH, Mackie K, Hohmann AG. Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice. Scientific Reports. 7: 944. PMID 28428628 DOI: 10.1038/s41598-017-01062-2 |
0.318 |
|
2017 |
Marcus DJ, Henderson-Redmond AN, Gonek M, Zee ML, Farnsworth JC, Amin RA, Andrews MJ, Davis BJ, Mackie K, Morgan DJ. Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. Plos One. 12: e0174826. PMID 28426670 DOI: 10.1371/journal.pone.0174826 |
0.441 |
|
2017 |
Cinar R, Gochuico BR, Iyer MR, Jourdan T, Yokoyama T, Park JK, Coffey NJ, Pri-Chen H, Szanda G, Liu Z, Mackie K, Gahl WA, Kunos G. Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. Jci Insight. 2. PMID 28422760 DOI: 10.1172/jci.insight.92281 |
0.318 |
|
2016 |
Sousa-Valente J, Varga A, Torres Perez JV, Jenes A, Wahba J, Mackie K, Cravatt B, Ueda N, Tsuboi K, Santha P, Jancso G, Tailor H, Avelino A, Nagy I. Inflammation of peripheral tissues and injury to peripheral nerves induce diferring effects in the expression of the calcium-sensitive anandamide-synthesising enzyme and related molecules in rat primary sensory neurons. The Journal of Comparative Neurology. PMID 27997038 DOI: 10.1002/Cne.24154 |
0.468 |
|
2016 |
Dhopeshwarkar A, Murataeva N, Makriyannis A, Straiker A, Mackie KP. Two Janus cannabinoids that are both CB2 agonists and CB1 antagonists. The Journal of Pharmacology and Experimental Therapeutics. PMID 27927913 DOI: 10.1124/Jpet.116.236539 |
0.833 |
|
2016 |
Fung S, Xu C, Hamel E, Wager-Miller JB, Woodruff G, Miller A, Sanford C, Mackie K, Stella N. Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration. Pharmacological Research. PMID 27832960 DOI: 10.1016/j.phrs.2016.10.025 |
0.481 |
|
2016 |
Chen J, Varga A, Selvarajah S, Jenes A, Dienes B, Sousa-Valente J, Kulik A, Veress G, Brain SD, Baker D, Urban L, Mackie K, Nagy I. Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk. Scientific Reports. 6: 33307. PMID 27653550 DOI: 10.1038/Srep33307 |
0.502 |
|
2016 |
Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. Eneuro. 3. PMID 27517090 DOI: 10.1523/ENEURO.0160-16.2016 |
0.512 |
|
2016 |
Marcus DJ, Zee ML, Davis BJ, Haskins CP, Andrews MJ, Amin R, Henderson-Redmond AN, Mackie K, Czyzyk TA, Morgan DJ. Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic. Plos One. 11: e0160462. PMID 27501235 DOI: 10.1371/Journal.Pone.0160462 |
0.745 |
|
2016 |
Tung LW, Lu GL, Lee YH, Yu L, Lee HJ, Leishman E, Bradshaw H, Hwang LL, Hung MS, Mackie K, Zimmer A, Chiou LC. Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons. Nature Communications. 7: 12199. PMID 27448020 DOI: 10.1038/ncomms12199 |
0.382 |
|
2016 |
Wager-Miller J, Mackie K. Quantitation of Plasma Membrane (G Protein-Coupled) Receptor Trafficking in Cultured Cells Methods of Molecular Biology. 1412: 255-266. PMID 27245911 DOI: 10.1007/978-1-4939-3539-0_26 |
0.441 |
|
2016 |
Wager-Miller J, Mackie K. Western Blotting of the Endocannabinoid System Methods of Molecular Biology. 1412: 247-254. PMID 27245910 DOI: 10.1007/978-1-4939-3539-0_25 |
0.399 |
|
2016 |
Pinheiro BS, Lemos C, Neutzling-Kaufmann F, Marques JM, da Silva-Santos CS, Carvalho E, Mackie K, Rodrigues RJ, Cunha RA, Köfalvi A. Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. Brain Research Bulletin. PMID 27208730 DOI: 10.1016/j.brainresbull.2016.05.009 |
0.311 |
|
2016 |
Dhopeshwarkar A, Mackie K. Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway. Journal of Pharmacology and Experimental Therapeutics. 358: 342-351. PMID 27194477 DOI: 10.1124/Jpet.116.232561 |
0.417 |
|
2016 |
Carey LM, Slivicki RA, Leishman E, Cornett B, Mackie K, Bradshaw H, Hohmann AG. A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular Pain. 12. PMID 27178246 DOI: 10.1177/1744806916649192 |
0.382 |
|
2016 |
Murataeva N, Dhopeshwarkar A, Yin D, Mitjavila J, Bradshaw H, Straiker A, Mackie K. WHERE's MY ENTOURAGE? THE CURIOUS CASE OF 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. Pharmacological Research. PMID 27117667 DOI: 10.1016/J.Phrs.2016.04.015 |
0.817 |
|
2016 |
Leishman E, Cornett B, Spork K, Straiker A, Mackie K, Bradshaw HB. Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain. Pharmacological Research. PMID 27109320 DOI: 10.1016/j.phrs.2016.04.020 |
0.761 |
|
2016 |
Delgado-Peraza F, Ahn K, Nogueras-Ortiz C, Mungrue I, Mackie KP, Kendall DA, Yudowski G. Mechanisms of biased beta-arrestin mediated signaling downstream from the cannabinoid 1 receptor. Molecular Pharmacology. PMID 27009233 DOI: 10.1124/Mol.115.103176 |
0.326 |
|
2016 |
Wang Y, Gu N, Duan T, Kesner P, Blaskovits F, Liu J, Lu Y, Tong L, Gao F, Harris C, Mackie K, Li J, Tan Q, Hill MN, Yuan Z, et al. Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses. Molecular Psychiatry. PMID 27001616 DOI: 10.1038/Mp.2016.22 |
0.348 |
|
2016 |
Xu C, Hermes DJ, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 26993829 DOI: 10.1007/S11481-016-9664-Y |
0.34 |
|
2016 |
Lee HJ, Chang LY, Ho YC, Teng SF, Hwang LL, Mackie K, Chiou LC. Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray. Neuropharmacology. PMID 26907809 DOI: 10.1016/j.neuropharm.2016.02.018 |
0.472 |
|
2015 |
Lu HC, Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry. PMID 26698193 DOI: 10.1016/j.biopsych.2015.07.028 |
0.509 |
|
2015 |
Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Björklund P, Mackie K, Di Marzo V, Hökfelt TG, Dobrzyn A, Harkany T. Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proceedings of the National Academy of Sciences of the United States of America. PMID 26494286 DOI: 10.1073/Pnas.1519040112 |
0.347 |
|
2015 |
Hu SS, Mackie K. Distribution of the Endocannabinoid System in the Central Nervous System. Handbook of Experimental Pharmacology. 231: 59-93. PMID 26408158 DOI: 10.1007/978-3-319-20825-1_3 |
0.582 |
|
2015 |
Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model. Pharmacological Research. 99: 370-6. PMID 26211948 DOI: 10.1016/j.phrs.2015.07.017 |
0.812 |
|
2015 |
Reyes BA, Heldt NA, Mackie K, Van Bockstaele EJ. Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons. Neuroscience. 303: 323-37. PMID 26162236 DOI: 10.1016/j.neuroscience.2015.07.009 |
0.394 |
|
2015 |
Marcus DJ, Zee M, Hughes A, Yuill MB, Hohmann AG, Mackie K, Guindon J, Morgan DJ. Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase. Molecular Pain. 11: 34. PMID 26065412 DOI: 10.1186/s12990-015-0031-4 |
0.459 |
|
2015 |
Murataeva N, Li S, Oehler O, Miller S, Dhopeshwarkar A, Hu SS, Bonanno JA, Bradshaw H, Mackie K, McHugh D, Straiker A. Cannabinoid-induced chemotaxis in bovine corneal epithelial cells. Investigative Ophthalmology & Visual Science. 56: 3304-13. PMID 26024113 DOI: 10.1167/Iovs.14-15675 |
0.811 |
|
2015 |
Janero DR, Yaddanapudi S, Zvonok N, Subramanian KV, Shukla VG, Stahl E, Zhou L, Hurst D, Wager-Miller J, Bohn LM, Reggio PH, Mackie K, Makriyannis A. Molecular-Interaction and Signaling Profiles of AM3677, a Novel Covalent Agonist Selective for the Cannabinoid 1 Receptor. Acs Chemical Neuroscience. PMID 25978068 DOI: 10.1021/Acschemneuro.5B00090 |
0.461 |
|
2015 |
Deng L, Cornett BL, Mackie K, Hohmann AG. CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain. Molecular Pharmacology. 88: 64-74. PMID 25904556 DOI: 10.1124/mol.115.098483 |
0.417 |
|
2015 |
Bashashati M, Nasser Y, Keenan CM, Ho W, Piscitelli F, Nalli M, Mackie K, Storr MA, Di Marzo V, Sharkey KA. Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. British Journal of Pharmacology. 172: 3099-111. PMID 25684407 DOI: 10.1111/Bph.13114 |
0.505 |
|
2015 |
Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE. Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Molecular Pharmacology. 87: 747-65. PMID 25657338 DOI: 10.1124/Mol.114.096495 |
0.82 |
|
2015 |
Mukhopadhyay B, Schuebel K, Mukhopadhyay P, Cinar R, Godlewski G, Xiong K, Mackie K, Lizak M, Yuan Q, Goldman D, Kunos G. Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology (Baltimore, Md.). 61: 1615-26. PMID 25580584 DOI: 10.1002/Hep.27686 |
0.317 |
|
2015 |
Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner. British Journal of Pharmacology. 172: 2406-18. PMID 25572435 DOI: 10.1111/Bph.13069 |
0.794 |
|
2015 |
Deng L, Guindon J, Cornett BL, Makriyannis A, Mackie K, Hohmann AG. Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal. Biological Psychiatry. 77: 475-87. PMID 24853387 DOI: 10.1016/j.biopsych.2014.04.009 |
0.501 |
|
2015 |
Straiker A, Mitjavila J, Yin D, Gibson A, Mackie K. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model Pharmacological Research. 99: 370-376. DOI: 10.1016/j.phrs.2015.07.017 |
0.744 |
|
2014 |
Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T. Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature Reviews. Neuroscience. 15: 786-801. PMID 25409697 DOI: 10.1038/Nrn3846 |
0.361 |
|
2014 |
Melis M, Sagheddu C, De Felice M, Casti A, Madeddu C, Spiga S, Muntoni AL, Mackie K, Marsicano G, Colombo G, Castelli MP, Pistis M. Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12716-24. PMID 25232109 DOI: 10.1523/Jneurosci.1844-14.2014 |
0.32 |
|
2014 |
Cathel AM, Reyes BA, Wang Q, Palma J, Mackie K, Van Bockstaele EJ, Kirby LG. Cannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortex. The European Journal of Neuroscience. 40: 3202-14. PMID 25131562 DOI: 10.1111/ejn.12690 |
0.421 |
|
2014 |
Dhopeshwarkar A, Mackie K. CB2cannabinoid receptors as a therapeutic target-what does the future hold? Molecular Pharmacology. 86: 430-437. PMID 25106425 DOI: 10.1124/Mol.114.094649 |
0.48 |
|
2014 |
Flores-Otero J, Ahn KH, Delgado-Peraza F, Mackie K, Kendall DA, Yudowski GA. Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature Communications. 5: 4589. PMID 25081814 DOI: 10.1038/Ncomms5589 |
0.446 |
|
2014 |
Wu CS, Morgan D, Jew CP, Haskins C, Andrews MJ, Leishman E, Spencer CM, Czyzyk T, Bradshaw H, Mackie K, Lu HC. Long-term consequences of perinatal fatty acid amino hydrolase inhibition. British Journal of Pharmacology. 171: 1420-34. PMID 24730060 DOI: 10.1111/Bph.12500 |
0.722 |
|
2014 |
Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K. Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5152-63. PMID 24719095 DOI: 10.1523/Jneurosci.3445-12.2014 |
0.815 |
|
2014 |
Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S. Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron. 81: 1111-25. PMID 24607231 DOI: 10.1016/J.Neuron.2014.01.012 |
0.352 |
|
2014 |
Hernández-Castellanos JM, Vivas O, Garduño J, De la Cruz L, Arenas I, ElÃas-Viñas D, Mackie K, GarcÃa DE. Gβ₂ mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons. Biochemical and Biophysical Research Communications. 445: 250-4. PMID 24513289 DOI: 10.1016/j.bbrc.2014.01.192 |
0.74 |
|
2014 |
Lovelace JW, Vieira PA, Corches A, Mackie K, Korzus E. Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1685-93. PMID 24457285 DOI: 10.1038/Npp.2014.15 |
0.342 |
|
2014 |
Murataeva N, Straiker A, Mackie K. Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. British Journal of Pharmacology. 171: 1379-91. PMID 24102242 DOI: 10.1111/Bph.12411 |
0.78 |
|
2014 |
Bashashati M, Ho W, Mackie K, Hollenberg MD, Sharkey KA. Sa2055 Alpha/Beta Hydrolase Domain 6 (ABHD6), A Novel Endocannabinoid Hydrolytic Enzyme, Regulates Contractility in the Mouse Intestine Gastroenterology. 146: S-365. DOI: 10.1016/S0016-5085(14)61322-6 |
0.459 |
|
2013 |
Cluny NL, Baraboi ED, Mackie K, Burdyga G, Richard D, Dockray GJ, Sharkey KA. High fat diet and body weight have different effects on cannabinoid CB(1) receptor expression in rat nodose ganglia. Autonomic Neuroscience : Basic & Clinical. 179: 122-30. PMID 24145047 DOI: 10.1016/J.Autneu.2013.09.015 |
0.454 |
|
2013 |
Petrov RR, Knight L, Chen SR, Wager-Miller J, McDaniel SW, Diaz F, Barth F, Pan HL, Mackie K, Cavasotto CN, Diaz P. Mastering tricyclic ring systems for desirable functional cannabinoid activity. European Journal of Medicinal Chemistry. 69: 881-907. PMID 24125850 DOI: 10.1016/j.ejmech.2013.09.038 |
0.438 |
|
2013 |
Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A. CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. The Journal of Biological Chemistry. 288: 32685-99. PMID 24089517 DOI: 10.1074/Jbc.M113.478354 |
0.362 |
|
2013 |
Garzón M, Duffy AM, Chan J, Lynch MK, Mackie K, Pickel VM. Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area. Neuroscience. 252: 126-43. PMID 23954803 DOI: 10.1016/J.Neuroscience.2013.08.008 |
0.448 |
|
2013 |
Jain T, Wager-Miller J, Mackie K, Straiker A. Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Molecular Pharmacology. 84: 296-302. PMID 23748223 DOI: 10.1124/mol.113.085217 |
0.809 |
|
2013 |
Cristino L, Busetto G, Imperatore R, Ferrandino I, Palomba L, Silvestri C, Petrosino S, Orlando P, Bentivoglio M, Mackie K, Di Marzo V. Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: E2229-38. PMID 23630288 DOI: 10.1073/Pnas.1219485110 |
0.391 |
|
2013 |
Li K, Fichna J, Schicho R, Saur D, Bashashati M, Mackie K, Li Y, Zimmer A, Göke B, Sharkey KA, Storr M. A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology. 71: 255-63. PMID 23603203 DOI: 10.1016/J.Neuropharm.2013.03.029 |
0.63 |
|
2013 |
Straiker A, Min KT, Mackie K. Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons. Neurobiology of Disease. 56: 1-5. PMID 23578490 DOI: 10.1016/J.Nbd.2013.04.002 |
0.807 |
|
2013 |
Wu CS, Chen H, Sun H, Zhu J, Jew CP, Wager-Miller J, Straiker A, Spencer C, Bradshaw H, Mackie K, Lu HC. GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. Plos One. 8: e60314. PMID 23565223 DOI: 10.1371/journal.pone.0060314 |
0.764 |
|
2013 |
Cottone E, Pomatto V, Cerri F, Campantico E, Mackie K, Delpero M, Guastalla A, Dati C, Bovolin P, Franzoni MF. Cannabinoid receptors are widely expressed in goldfish: Molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs Fish Physiology and Biochemistry. 39: 1287-1296. PMID 23504102 DOI: 10.1007/s10695-013-9783-9 |
0.471 |
|
2013 |
Shonesy BC, Wang X, Rose KL, Ramikie TS, Cavener VS, Rentz T, Baucum AJ, Jalan-Sakrikar N, Mackie K, Winder DG, Patel S, Colbran RJ. CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling. Nature Neuroscience. 16: 456-63. PMID 23502535 DOI: 10.1038/Nn.3353 |
0.385 |
|
2013 |
Fitzgerald ML, Mackie K, Pickel VM. The impact of adolescent social isolation on dopamine D2 and cannabinoid CB1 receptors in the adult rat prefrontal cortex. Neuroscience. 235: 40-50. PMID 23333674 DOI: 10.1016/J.Neuroscience.2013.01.021 |
0.363 |
|
2013 |
Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 1935-40. PMID 23319656 DOI: 10.1073/Pnas.1212563110 |
0.616 |
|
2013 |
Horne EA, Coy J, Swinney K, Fung S, Cherry AE, Marrs WR, Naydenov AV, Lin YH, Sun X, Keene CD, Grouzmann E, Muchowski P, Bates GP, Mackie K, Stella N. Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European Journal of Neuroscience. 37: 429-40. PMID 23167744 DOI: 10.1111/Ejn.12045 |
0.442 |
|
2013 |
Veress G, Meszar Z, Muszil D, Avelino A, Matesz K, Mackie K, Nagy I. Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons. Brain Structure & Function. 218: 733-50. PMID 22618437 DOI: 10.1007/s00429-012-0425-2 |
0.476 |
|
2012 |
Péterfi Z, Urbán GM, Papp OI, Németh B, Monyer H, Szabó G, Erdélyi F, Mackie K, Freund TF, Hájos N, Katona I. Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14448-63. PMID 23055515 DOI: 10.1523/Jneurosci.1676-12.2012 |
0.418 |
|
2012 |
Hu H, Ho W, Mackie K, Pittman QJ, Sharkey KA. Brain CBâ‚ receptor expression following lipopolysaccharide-induced inflammation. Neuroscience. 227: 211-22. PMID 23041513 DOI: 10.1016/J.Neuroscience.2012.09.067 |
0.54 |
|
2012 |
Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature Communications. 3: 1080. PMID 23011134 DOI: 10.1038/Ncomms2045 |
0.547 |
|
2012 |
Murataeva N, Mackie K, Straiker A. The CB2-preferring agonist JWH015 also potently and efficaciously activates CB1 in autaptic hippocampal neurons. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 66: 437-42. PMID 22921769 DOI: 10.1016/J.Phrs.2012.08.002 |
0.839 |
|
2012 |
Pickel VM, Shobin ET, Lane DA, Mackie K. Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals. Neuroscience. 227: 10-21. PMID 22863674 DOI: 10.1016/j.neuroscience.2012.07.050 |
0.326 |
|
2012 |
Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9457-68. PMID 22787031 DOI: 10.1523/Jneurosci.0013-12.2012 |
0.575 |
|
2012 |
Ferreira SG, Teixeira FM, Garção P, Agostinho P, Ledent C, Cortes L, MacKie K, Köfalvi A. Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences Neurochemistry International. 61: 219-226. PMID 22609378 DOI: 10.1016/j.neuint.2012.05.009 |
0.33 |
|
2012 |
Fitzgerald ML, Chan J, Mackie K, Lupica CR, Pickel VM. Altered dendritic distribution of dopamine D2 receptors and reduction in mitochondrial number in parvalbumin-containing interneurons in the medial prefrontal cortex of cannabinoid-1 (CB1) receptor knockout mice. The Journal of Comparative Neurology. 520: 4013-31. PMID 22592925 DOI: 10.1002/Cne.23141 |
0.419 |
|
2012 |
Atwood BK, Straiker A, Mackie K. CBâ‚‚ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons. Neuropharmacology. 63: 514-23. PMID 22579668 DOI: 10.1016/J.Neuropharm.2012.04.024 |
0.818 |
|
2012 |
Hegyi Z, Holló K, Kis G, Mackie K, Antal M. Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. Glia. 60: 1316-29. PMID 22573306 DOI: 10.1002/glia.22351 |
0.335 |
|
2012 |
Pacher P, Mackie K. Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration Journal of Molecular Medicine. 90: 347-351. PMID 22371074 DOI: 10.1007/s00109-012-0884-1 |
0.409 |
|
2012 |
Rajesh M, Bátkai S, Kechrid M, Mukhopadhyay P, Lee WS, Horváth B, Holovac E, Cinar R, Liaudet L, Mackie K, Haskó G, Pacher P. Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. Diabetes. 61: 716-27. PMID 22315315 DOI: 10.2337/db11-0477 |
0.411 |
|
2012 |
Hons IM, Storr MA, Mackie K, Lutz B, Pittman QJ, Mawe GM, Sharkey KA. Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: e113-24. PMID 22235973 DOI: 10.1111/J.1365-2982.2011.01860.X |
0.599 |
|
2012 |
Keimpema E, Straiker A, Mackie K, Harkany T, Hjerling-Leffler J. Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. The Journal of Physiology. 590: 703-14. PMID 22219340 DOI: 10.1113/Jphysiol.2011.224386 |
0.751 |
|
2012 |
Atwood BK, Straiker A, Mackie K. CBâ‚‚: therapeutic target-in-waiting. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 16-20. PMID 22197668 DOI: 10.1016/J.Pnpbp.2011.12.001 |
0.808 |
|
2012 |
Lane DA, Chan J, Fitzgerald ML, Kearn CS, Mackie K, Pickel VM. Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology. 221: 101-13. PMID 22160162 DOI: 10.1007/S00213-011-2553-4 |
0.365 |
|
2012 |
Atwood BK, Wager-Miller J, Haskins C, Straiker A, Mackie K. Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands. Molecular Pharmacology. 81: 250-63. PMID 22064678 DOI: 10.1124/Mol.111.074013 |
0.844 |
|
2012 |
Straiker A, Wager-Miller J, Hutchens J, Mackie K. Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2660-71. PMID 22014238 DOI: 10.1111/j.1476-5381.2011.01744.x |
0.832 |
|
2012 |
Straiker A, Wager-Miller J, Mackie K. The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones. British Journal of Pharmacology. 165: 2652-9. PMID 22014214 DOI: 10.1111/j.1476-5381.2011.01743.x |
0.83 |
|
2012 |
López-Gallardo M, López-Rodríguez AB, Llorente-Berzal Á, Rotllant D, Mackie K, Armario A, Nadal R, Viveros MP. Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion. Neuroscience. 204: 90-103. PMID 22001306 DOI: 10.1016/J.Neuroscience.2011.09.063 |
0.329 |
|
2012 |
Bashashati M, Storr MA, Nikas SP, Wood JT, Godlewski G, Liu J, Ho W, Keenan CM, Zhang H, Alapafuja SO, Cravatt BF, Lutz B, Mackie K, Kunos G, Patel KD, et al. Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. British Journal of Pharmacology. 165: 1556-71. PMID 21883147 DOI: 10.1111/J.1476-5381.2011.01644.X |
0.57 |
|
2012 |
Morgan DJ, Muller CH, Murataeva NA, Davis BJ, Mackie K. Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity. British Journal of Pharmacology. 165: 2575-83. PMID 21615727 DOI: 10.1111/J.1476-5381.2011.01506.X |
0.778 |
|
2011 |
Ho YC, Lee HJ, Tung LW, Liao YY, Fu SY, Teng SF, Liao HT, Mackie K, Chiou LC. Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14600-10. PMID 21994376 DOI: 10.1523/Jneurosci.2671-11.2011 |
0.445 |
|
2011 |
Duffy AM, Fitzgerald ML, Chan J, Robinson DC, Milner TA, Mackie K, Pickel VM. Acetylcholine α7 nicotinic and dopamine D2 receptors are targeted to many of the same postsynaptic dendrites and astrocytes in the rodent prefrontal cortex. Synapse (New York, N.Y.). 65: 1350-67. PMID 21858872 DOI: 10.1002/Syn.20977 |
0.33 |
|
2011 |
Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ. Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10506-15. PMID 21775596 DOI: 10.1523/Jneurosci.0496-11.2011 |
0.461 |
|
2011 |
Keimpema E, Mackie K, Harkany T. Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in Pharmacological Sciences. 32: 551-61. PMID 21757242 DOI: 10.1016/J.Tips.2011.05.004 |
0.475 |
|
2011 |
Schicho R, Bashashati M, Bawa M, McHugh D, Saur D, Hu HM, Zimmer A, Lutz B, Mackie K, Bradshaw HB, McCafferty DM, Sharkey KA, Storr M. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflammatory Bowel Diseases. 17: 1651-64. PMID 21744421 DOI: 10.1002/Ibd.21538 |
0.555 |
|
2011 |
Straiker A, Wager-Miller J, Hu SS, Blankman JL, Cravatt BF, Mackie K. COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation. British Journal of Pharmacology. 164: 1672-83. PMID 21564090 DOI: 10.1111/J.1476-5381.2011.01486.X |
0.79 |
|
2011 |
Hemmings HC, Mackie K. The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation. Anesthesiology. 114: 1277-9. PMID 21532461 DOI: 10.1097/ALN.0b013e31821c647d |
0.467 |
|
2011 |
Mulder J, Zilberter M, Pasquaré SJ, Alpár A, Schulte G, Ferreira SG, Köfalvi A, MartÃn-Moreno AM, Keimpema E, Tanila H, Watanabe M, Mackie K, Hortobágyi T, de Ceballos ML, Harkany T. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a Journal of Neurology. 134: 1041-60. PMID 21459826 DOI: 10.1093/Brain/Awr046 |
0.418 |
|
2011 |
Atwood BK, Lee D, Straiker A, Widlanski TS, Mackie K. CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. European Journal of Pharmacology. 659: 139-45. PMID 21333643 DOI: 10.1016/J.Ejphar.2011.01.066 |
0.837 |
|
2011 |
Atwood BK, Lopez J, Wager-Miller J, Mackie K, Straiker A. Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. Bmc Genomics. 12: 14. PMID 21214938 DOI: 10.1186/1471-2164-12-14 |
0.8 |
|
2011 |
Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG. Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. Journal of Neurophysiology. 105: 958-63. PMID 21084685 DOI: 10.1152/Jn.00980.2010 |
0.332 |
|
2011 |
Ludányi A, Hu SS, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. Neuroscience. 174: 50-63. PMID 21035522 DOI: 10.1016/J.Neuroscience.2010.10.062 |
0.523 |
|
2011 |
Halleskog C, Mulder J, Dahlström J, Mackie K, Hortobágyi T, Tanila H, Kumar Puli L, Färber K, Harkany T, Schulte G. WNT signaling in activated microglia is proinflammatory. Glia. 59: 119-31. PMID 20967887 DOI: 10.1002/Glia.21081 |
0.363 |
|
2011 |
Atwood B, MacKie K. Reply by authors to letter from Ashton British Journal of Pharmacology. 163: 1114. DOI: 10.1111/J.1476-5381.2010.01140.X |
0.712 |
|
2011 |
Ludányi A, Hu SSJ, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Corrigendum to "Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus". [Neuroscience 174 (2011) 50-63]. Neuroscience. 186: 220. DOI: 10.1016/J.Neuroscience.2011.04.072 |
0.432 |
|
2010 |
Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CBâ‚ and CBâ‚‚. Pharmacological Reviews. 62: 588-631. PMID 21079038 DOI: 10.1124/Pr.110.003004 |
0.495 |
|
2010 |
Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC. Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. The European Journal of Neuroscience. 32: 693-706. PMID 21050275 DOI: 10.1111/j.1460-9568.2010.07337.x |
0.347 |
|
2010 |
Dmitrieva N, Nagabukuro H, Resuehr D, Zhang G, McAllister SL, McGinty KA, Mackie K, Berkley KJ. Endocannabinoid involvement in endometriosis. Pain. 151: 703-10. PMID 20833475 DOI: 10.1016/J.Pain.2010.08.037 |
0.331 |
|
2010 |
Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, ... ... Mackie K, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature Neuroscience. 13: 951-7. PMID 20657592 DOI: 10.1038/Nn.2601 |
0.645 |
|
2010 |
Hu SS, Arnold A, Hutchens JM, Radicke J, Cravatt BF, Wager-Miller J, Mackie K, Straiker A. Architecture of cannabinoid signaling in mouse retina. The Journal of Comparative Neurology. 518: 3848-66. PMID 20653038 DOI: 10.1002/Cne.22429 |
0.819 |
|
2010 |
Maglóczky Z, Tóth K, Karlócai R, Nagy S, Eross L, Czirják S, Vajda J, Rásonyi G, Kelemen A, Juhos V, Halász P, Mackie K, Freund TF. Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. Epilepsia. 51: 115-20. PMID 20618415 DOI: 10.1111/J.1528-1167.2010.02624.X |
0.459 |
|
2010 |
Rajesh M, Mukhopadhyay P, Haskó G, Liaudet L, Mackie K, Pacher P. Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells British Journal of Pharmacology. 160: 688-700. PMID 20590572 DOI: 10.1111/J.1476-5381.2010.00712.X |
0.413 |
|
2010 |
Mukhopadhyay P, Pan H, Rajesh M, Bátkai S, Patel V, Harvey-White J, Mukhopadhyay B, Haskó G, Gao B, Mackie K, Pacher P. CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. British Journal of Pharmacology. 160: 657-68. PMID 20590569 DOI: 10.1111/j.1476-5381.2010.00769.x |
0.4 |
|
2010 |
Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. British Journal of Pharmacology. 160: 467-79. PMID 20590558 DOI: 10.1111/J.1476-5381.2010.00729.X |
0.724 |
|
2010 |
Massa F, Mancini G, Schmidt H, Steindel F, Mackie K, Angioni C, Oliet SH, Geisslinger G, Lutz B. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6273-81. PMID 20445053 DOI: 10.1523/JNEUROSCI.2648-09.2010 |
0.457 |
|
2010 |
Mukhopadhyay B, Liu J, Osei-Hyiaman D, Godlewski G, Mukhopadhyay P, Wang L, Jeong WI, Gao B, Duester G, Mackie K, Kojima S, Kunos G. Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-γ Journal of Biological Chemistry. 285: 19002-19011. PMID 20410309 DOI: 10.1074/jbc.M109.068460 |
0.363 |
|
2010 |
Storr MA, Bashashati M, Hirota C, Vemuri VK, Keenan CM, Duncan M, Lutz B, Mackie K, Makriyannis A, Macnaughton WK, Sharkey KA. Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 787-96, e223. PMID 20180825 DOI: 10.1111/J.1365-2982.2010.01478.X |
0.608 |
|
2010 |
Atwood BK, Huffman J, Straiker A, Mackie K. JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. British Journal of Pharmacology. 160: 585-93. PMID 20100276 DOI: 10.1111/J.1476-5381.2009.00582.X |
0.854 |
|
2010 |
Walsh S, Mnich K, Mackie K, Gorman AM, Finn DP, Dowd E. Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. Brain Research Bulletin. 81: 543-8. PMID 20097273 DOI: 10.1016/j.brainresbull.2010.01.009 |
0.411 |
|
2010 |
Carvalho AF, Mackie K, Van Bockstaele EJ. Cannabinoid modulation of limbic forebrain noradrenergic circuitry. The European Journal of Neuroscience. 31: 286-301. PMID 20074224 DOI: 10.1111/j.1460-9568.2009.07054.x |
0.405 |
|
2010 |
Trimpin S, Herath TN, Inutan ED, Wager-Miller J, Kowalski P, Claude E, Walker JM, Mackie K. Automated solvent-free matrix deposition for tissue imaging by mass spectrometry. Analytical Chemistry. 82: 359-67. PMID 19968249 DOI: 10.1021/Ac902065U |
0.311 |
|
2010 |
Mukhopadhyay P, Rajesh M, Bátkai S, Patel V, Kashiwaya Y, Liaudet L, Evgenov OV, Mackie K, Haskó G, Pacher P. CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. Cardiovascular Research. 85: 773-84. PMID 19942623 DOI: 10.1093/cvr/cvp369 |
0.367 |
|
2010 |
Lipina C, Stretton C, Hastings S, Hundal JS, Mackie K, Irving AJ, Hundal HS. Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells. Diabetes. 59: 375-85. PMID 19933999 DOI: 10.2337/db09-0979 |
0.385 |
|
2010 |
Scavone JL, Mackie K, Van Bockstaele EJ. Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors. Brain Research. 1312: 18-31. PMID 19931229 DOI: 10.1016/j.brainres.2009.11.023 |
0.373 |
|
2010 |
Roche M, Johnston P, Mhuircheartaigh ON, Olango WM, Mackie K, Finn DP. Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear. European Journal of Pain (London, England). 14: 487-95. PMID 19786358 DOI: 10.1016/j.ejpain.2009.08.009 |
0.368 |
|
2009 |
Yao B, Mackie K. Endocannabinoid receptor pharmacology. Current Topics in Behavioral Neurosciences. 1: 37-63. PMID 21104379 DOI: 10.1007/978-3-540-88955-7_2 |
0.508 |
|
2009 |
Whyte LS, Ryberg E, Sims NA, Ridge SA, Mackie K, Greasley PJ, Ross RA, Rogers MJ. The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 16511-6. PMID 19805329 DOI: 10.1073/pnas.0902743106 |
0.339 |
|
2009 |
Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, Mackie K. Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Molecular Pharmacology. 76: 1220-7. PMID 19767452 DOI: 10.1124/Mol.109.059030 |
0.819 |
|
2009 |
Mackie K, Katona I. Get stoned in GABAergic synapses. Nature Neuroscience. 12: 1081-3. PMID 19710646 DOI: 10.1038/Nn0909-1081 |
0.324 |
|
2009 |
Straiker A, Mackie K. Cannabinoid signaling in inhibitory autaptic hippocampal neurons. Neuroscience. 163: 190-201. PMID 19501632 DOI: 10.1016/j.neuroscience.2009.06.004 |
0.797 |
|
2009 |
Kellogg R, Mackie K, Straiker A. Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons. Journal of Neurophysiology. 102: 1160-71. PMID 19494194 DOI: 10.1152/jn.00266.2009 |
0.818 |
|
2009 |
Cottone E, Guastalla A, Pomatto V, Campantico E, Palermo F, Magni AMP, Mackie K, Franzoni MF. Interplay of the Endocannabinoid System with Neuropeptide Y and Corticotropin-releasing Factor in the Goldfish Forebrain Annals of the New York Academy of Sciences. 1163: 372-375. PMID 19456363 DOI: 10.1111/J.1749-6632.2009.04432.X |
0.324 |
|
2009 |
Nyilas R, Gregg LC, Mackie K, Watanabe M, Zimmer A, Hohmann AG, Katona I. Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. The European Journal of Neuroscience. 29: 1964-78. PMID 19453631 DOI: 10.1111/J.1460-9568.2009.06751.X |
0.384 |
|
2009 |
Trabucco E, Acone G, Marenna A, Pierantoni R, Cacciola G, Chioccarelli T, Mackie K, Fasano S, Colacurci N, Meccariello R, Cobellis G, Cobellis L. Endocannabinoid system in first trimester placenta: low FAAH and high CB1 expression characterize spontaneous miscarriage. Placenta. 30: 516-522. PMID 19419760 DOI: 10.1016/J.Placenta.2009.03.015 |
0.341 |
|
2009 |
Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131 |
0.548 |
|
2009 |
Acone G, Trabucco E, Colacurci N, Cobellis L, Mackie K, Meccariello R, Cacciola G, Chioccarelli T, Fasano S, Pierantoni R, Cobellis G. Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. Placenta. 30: 203-205. PMID 19097644 DOI: 10.1016/J.Placenta.2008.11.018 |
0.396 |
|
2009 |
Whyte L, Ryberg E, Sims NA, Ridge S, Mackie K, Greasley P, Ross RA, Rogers MJ. GPR55: A novel cannabinoid receptor involved in the regulation of osteoclast function and bone mass Bone. 44. DOI: 10.1016/J.Bone.2009.01.305 |
0.366 |
|
2008 |
Harkany T, Mackie K, Doherty P. Wiring and firing neuronal networks: endocannabinoids take center stage. Current Opinion in Neurobiology. 18: 338-45. PMID 18801434 DOI: 10.1016/J.Conb.2008.08.007 |
0.406 |
|
2008 |
Cacciola G, Chioccarelli T, Mackie K, Meccariello R, Ledent C, Fasano S, Pierantoni R, Cobellis G. Expression of Type-1 Cannabinoid Receptor During Rat Postnatal Testicular Development: Possible Involvement in Adult Leydig Cell Differentiation Biology of Reproduction. 79: 758-765. PMID 18614700 DOI: 10.1095/Biolreprod.108.070128 |
0.409 |
|
2008 |
Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu HC, et al. Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proceedings of the National Academy of Sciences of the United States of America. 105: 8760-5. PMID 18562289 DOI: 10.1073/Pnas.0803545105 |
0.316 |
|
2008 |
Suárez J, Bermúdez-Silva FJ, Mackie K, Ledent C, Zimmer A, Cravatt BF, de Fonseca FR. Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei. The Journal of Comparative Neurology. 509: 400-21. PMID 18521853 DOI: 10.1002/Cne.21774 |
0.396 |
|
2008 |
Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3024-34. PMID 18492727 DOI: 10.1096/Fj.07-101865 |
0.782 |
|
2008 |
Duncan M, Mouihate A, Mackie K, Keenan CM, Buckley NE, Davison JS, Patel KD, Pittman QJ, Sharkey KA. Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G78-G87. PMID 18483180 DOI: 10.1152/Ajpgi.90285.2008 |
0.628 |
|
2008 |
Mackie K. Cannabinoid Receptors: Where They are and What They do Journal of Neuroendocrinology. 20: 10-14. PMID 18426493 DOI: 10.1111/J.1365-2826.2008.01671.X |
0.458 |
|
2008 |
Cinar R, Freund TF, Katona I, Mackie K, Szucs M. Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes. Neurochemistry International. 52: 1402-9. PMID 18407377 DOI: 10.1016/J.Neuint.2008.02.005 |
0.453 |
|
2008 |
Cottone E, Guastalla A, Mackie K, Franzoni MF. Endocannabinoids affect the reproductive functions in teleosts and amphibians. Molecular and Cellular Endocrinology. 286. PMID 18343023 DOI: 10.1016/J.Mce.2008.01.025 |
0.501 |
|
2008 |
Mackie K. Signaling via CNS cannabinoid receptors. Molecular and Cellular Endocrinology. 286. PMID 18336996 DOI: 10.1016/J.Mce.2008.01.022 |
0.528 |
|
2008 |
Daigle TL, Kwok ML, Mackie K. Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism. Journal of Neurochemistry. 106: 70-82. PMID 18331587 DOI: 10.1111/j.1471-4159.2008.05336.x |
0.726 |
|
2008 |
Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K. GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proceedings of the National Academy of Sciences of the United States of America. 105: 2699-704. PMID 18263732 DOI: 10.1073/Pnas.0711278105 |
0.836 |
|
2008 |
Nyilas R, Dudok B, Urbán GM, Mackie K, Watanabe M, Cravatt BF, Freund TF, Katona I. Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1058-63. PMID 18234884 DOI: 10.1523/Jneurosci.5102-07.2008 |
0.399 |
|
2008 |
Malone DT, Kearn CS, Chongue L, Mackie K, Taylor DA. Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience. 152: 265-72. PMID 18082330 DOI: 10.1016/j.neuroscience.2007.10.043 |
0.375 |
|
2008 |
Rajesh M, Mukhopadhyay P, Haskó G, Huffman JW, Mackie K, Pacher P. CB2 cannabinoid receptor agonists attenuate TNF-α-induced human vascular smooth muscle cell proliferation and migration British Journal of Pharmacology. 153: 347-357. PMID 17994109 DOI: 10.1038/Sj.Bjp.0707569 |
0.414 |
|
2008 |
Rimmerman N, Hughes HV, Bradshaw HB, Pazos MX, Mackie K, Prieto AL, Walker JM. Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. British Journal of Pharmacology. 153: 380-9. PMID 17965731 DOI: 10.1038/Sj.Bjp.0707561 |
0.445 |
|
2008 |
Daigle TL, Kearn CS, Mackie K. Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling. Neuropharmacology. 54: 36-44. PMID 17681354 DOI: 10.1016/j.neuropharm.2007.06.005 |
0.776 |
|
2008 |
Mátyás F, Urbán GM, Watanabe M, Mackie K, Zimmer A, Freund TF, Katona I. Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area. Neuropharmacology. 54: 95-107. PMID 17655884 DOI: 10.1016/J.Neuropharm.2007.05.028 |
0.372 |
|
2008 |
Nesto RW, Mackie K. Endocannabinoid system and its implications for obesity and cardiometabolic risk European Heart Journal. 10. DOI: 10.1093/Eurheartj/Sum052 |
0.303 |
|
2008 |
Mackie K, Ross RA. CB 2 cannabinoid receptors: New vistas British Journal of Pharmacology. 153: 177-178. DOI: 10.1038/sj.bjp.0707617 |
0.475 |
|
2007 |
Cachope R, Mackie K, Triller A, O'Brien J, Pereda AE. Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron. 56: 1034-47. PMID 18093525 DOI: 10.1016/J.Neuron.2007.11.014 |
0.358 |
|
2007 |
Mackie K. From active ingredients to the discovery of the targets: the cannabinoid receptors. Chemistry & Biodiversity. 4: 1693-1706. PMID 17712815 DOI: 10.1002/Cbdv.200790148 |
0.432 |
|
2007 |
Rajesh M, Mukhopadhyay P, Batkai S, Hasko G, Liaudet L, Huffman JW, Csiszar A, Ungvari ZI, Mackie K, Chatterjee S, Pacher P. CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion American Journal of Physiology-Heart and Circulatory Physiology. 293. PMID 17660390 DOI: 10.1152/Ajpheart.00688.2007 |
0.408 |
|
2007 |
Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Molecular Pharmacology. 72: 612-21. PMID 17584991 DOI: 10.1124/Mol.107.037796 |
0.531 |
|
2007 |
Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, et al. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nature Neuroscience. 10: 870-9. PMID 17558404 DOI: 10.1038/Nn1916 |
0.446 |
|
2007 |
Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, ... Mackie K, et al. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (New York, N.Y.). 316: 1212-6. PMID 17525344 DOI: 10.1126/Science.1137406 |
0.381 |
|
2007 |
Castelli MP, Piras AP, Melis T, Succu S, Sanna F, Melis MR, Collu S, Ennas MG, Diaz G, Mackie K, Argiolas A. Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies. Neuroscience. 147: 197-206. PMID 17507169 DOI: 10.1016/j.neuroscience.2007.02.062 |
0.475 |
|
2007 |
Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. A molecular basis of analgesic tolerance to cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4165-77. PMID 17428994 DOI: 10.1523/Jneurosci.5648-06.2007 |
0.477 |
|
2007 |
Mitrirattanakul S, López-Valdés HE, Liang J, Matsuka Y, Mackie K, Faull KF, Spigelman I. Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence. Alcoholism, Clinical and Experimental Research. 31: 855-67. PMID 17386072 DOI: 10.1111/J.1530-0277.2007.00366.X |
0.342 |
|
2007 |
Harkany T, Guzmán M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K. The emerging functions of endocannabinoid signaling during CNS development. Trends in Pharmacological Sciences. 28: 83-92. PMID 17222464 DOI: 10.1016/J.Tips.2006.12.004 |
0.347 |
|
2007 |
Duarte JM, Nogueira C, Mackie K, Oliveira CR, Cunha RA, Köfalvi A. Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats. Experimental Neurology. 204: 479-84. PMID 17222407 DOI: 10.1016/j.expneurol.2006.11.013 |
0.349 |
|
2007 |
Deshmukh S, Onozuka K, Bender KJ, Bender VA, Lutz B, Mackie K, Feldman DE. Postnatal development of cannabinoid receptor type 1 expression in rodent somatosensory cortex. Neuroscience. 145: 279-87. PMID 17210229 DOI: 10.1016/J.Neuroscience.2006.11.033 |
0.44 |
|
2007 |
Chen K, Neu A, Howard AL, Földy C, Echegoyen J, Hilgenberg L, Smith M, Mackie K, Soltesz I. Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 46-58. PMID 17202471 DOI: 10.1523/Jneurosci.3966-06.2007 |
0.366 |
|
2007 |
Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K, Piomelli D. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. The Journal of Biological Chemistry. 282: 1518-28. PMID 17121838 DOI: 10.1074/Jbc.M607809200 |
0.51 |
|
2007 |
Oropeza VC, Mackie K, Van Bockstaele EJ. Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex. Brain Research. 1127: 36-44. PMID 17113043 DOI: 10.1016/j.brainres.2006.09.110 |
0.384 |
|
2007 |
Straiker A, Mackie K. Metabotropic suppression of excitation in murine autaptic hippocampal neurons. The Journal of Physiology. 578: 773-85. PMID 17110416 DOI: 10.1113/jphysiol.2006.117499 |
0.834 |
|
2006 |
Cenni G, Blandina P, Mackie K, Nosi D, Formigli L, Giannoni P, Ballini C, Corte LD, Mannaioni PF, Passani MB. Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain. European Journal of Neuroscience. 24: 1633-1644. PMID 17004927 DOI: 10.1111/J.1460-9568.2006.05046.X |
0.352 |
|
2006 |
Monory K, Massa F, Egertová M, Eder M, Blaudzun H, Westenbroek R, Kelsch W, Jacob W, Marsch R, Ekker M, Long J, Rubenstein JL, Goebbels S, Nave KA, During M, ... ... Mackie K, et al. The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron. 51: 455-66. PMID 16908411 DOI: 10.1016/J.Neuron.2006.07.006 |
0.398 |
|
2006 |
Mitrirattanakul S, Ramakul N, Guerrero AV, Matsuka Y, Ono T, Iwase H, Mackie K, Faull KF, Spigelman I. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain. 126: 102-14. PMID 16844297 DOI: 10.1016/J.Pain.2006.06.016 |
0.357 |
|
2006 |
Mackie K, Stella N. Cannabinoid receptors and endocannabinoids: evidence for new players. The Aaps Journal. 8: E298-306. PMID 16796380 DOI: 10.1208/aapsj080234 |
0.528 |
|
2006 |
Straiker A, Mackie K. Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 years. The Aaps Journal. 8: E272-6. PMID 16796377 DOI: 10.1208/aapsj080231 |
0.815 |
|
2006 |
Katona I, Urbán GM, Wallace M, Ledent C, Jung KM, Piomelli D, Mackie K, Freund TF. Molecular composition of the endocannabinoid system at glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5628-37. PMID 16723519 DOI: 10.1523/Jneurosci.0309-06.2006 |
0.532 |
|
2006 |
Cobellis G, Cacciola G, Scarpa D, Meccariello R, Chianese R, Franzoni MF, Mackie K, Pierantoni R, Fasano S. Endocannabinoid System in Frog and Rodent Testis: Type-1 Cannabinoid Receptor and Fatty Acid Amide Hydrolase Activity in Male Germ Cells Biology of Reproduction. 75: 82-89. PMID 16611862 DOI: 10.1095/Biolreprod.106.051730 |
0.413 |
|
2006 |
Mackie K. Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength. International Journal of Obesity. 30. PMID 16570100 DOI: 10.1038/Sj.Ijo.0803273 |
0.52 |
|
2006 |
Pickel VM, Chan J, Kearn CS, Mackie K. Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens. The Journal of Comparative Neurology. 495: 299-313. PMID 16440297 DOI: 10.1002/cne.20881 |
0.445 |
|
2006 |
Mackie K. Cannabinoid receptors as therapeutic targets. Annual Review of Pharmacology and Toxicology. 46: 101-122. PMID 16402900 DOI: 10.1146/Annurev.Pharmtox.46.120604.141254 |
0.465 |
|
2006 |
Mátyás F, Yanovsky Y, Mackie K, Kelsch W, Misgeld U, Freund TF. Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia. Neuroscience. 137: 337-61. PMID 16289348 DOI: 10.1016/J.Neuroscience.2005.09.005 |
0.467 |
|
2005 |
Mackie K. Distribution of cannabinoid receptors in the central and peripheral nervous system. Handbook of Experimental Pharmacology. 168: 299-325. PMID 16596779 DOI: 10.1007/3-540-26573-2_10 |
0.504 |
|
2005 |
Lauckner JE, Hille B, Mackie K. The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 19144-9. PMID 16365309 DOI: 10.1073/pnas.0509588102 |
0.806 |
|
2005 |
Berghuis P, Dobszay MB, Wang X, Spano S, Ledda F, Sousa KM, Schulte G, Ernfors P, Mackie K, Paratcha G, Hurd YL, Harkany T. Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 19115-20. PMID 16357196 DOI: 10.1073/Pnas.0509494102 |
0.478 |
|
2005 |
NyÃri G, Cserép C, Szabadits E, Mackie K, Freund TF. CB1 cannabinoid receptors are enriched in the perisynaptic annulus and on preterminal segments of hippocampal GABAergic axons. Neuroscience. 136: 811-22. PMID 16344153 DOI: 10.1016/j.neuroscience.2005.01.026 |
0.474 |
|
2005 |
Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (New York, N.Y.). 310: 329-32. PMID 16224028 DOI: 10.1126/Science.1115740 |
0.729 |
|
2005 |
Straiker A, Mackie K. Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. The Journal of Physiology. 569: 501-17. PMID 16179366 DOI: 10.1113/jphysiol.2005.091918 |
0.81 |
|
2005 |
Osei-Hyiaman D, Depetrillo M, Harvey-White J, Bannon AW, Cravatt BF, Kuhar MJ, Mackie K, Palkovits M, Kunos G. Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology. 81: 273-82. PMID 16131814 DOI: 10.1159/000087925 |
0.34 |
|
2005 |
Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K, Hille B. Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. The Journal of General Physiology. 126: 243-62. PMID 16129772 DOI: 10.1085/Jgp.200509309 |
0.723 |
|
2005 |
Harkany T, Dobszay MB, Cayetanot F, Härtig W, Siegemund T, Aujard F, Mackie K. Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat. Neuroscience. 135: 595-609. PMID 16129564 DOI: 10.1016/J.Neuroscience.2005.06.043 |
0.478 |
|
2005 |
Jung KM, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, Mackie K, Piomelli D. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Molecular Pharmacology. 68: 1196-202. PMID 16051747 DOI: 10.1124/Mol.105.013961 |
0.628 |
|
2005 |
Bodor AL, Katona I, NyÃri G, Mackie K, Ledent C, Hájos N, Freund TF. Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6845-56. PMID 16033894 DOI: 10.1523/Jneurosci.0442-05.2005 |
0.334 |
|
2005 |
Mackie K. Cannabinoid receptor homo- and heterodimerization. Life Sciences. 77: 1667-1673. PMID 15978631 DOI: 10.1016/J.Lfs.2005.05.011 |
0.461 |
|
2005 |
NyÃri G, Szabadits E, Cserép C, Mackie K, Shigemoto R, Freund TF. GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons. The European Journal of Neuroscience. 21: 3034-42. PMID 15978014 DOI: 10.1111/j.1460-9568.2005.04146.x |
0.323 |
|
2005 |
Osei-Hyiaman D, DePetrillo M, Pacher P, Liu J, Radaeva S, Bátkai S, Harvey-White J, Mackie K, Offertáler L, Wang L, Kunos G. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. The Journal of Clinical Investigation. 115: 1298-305. PMID 15864349 DOI: 10.1172/JCI23057 |
0.347 |
|
2005 |
Cottone E, Forno S, Campantico E, Guastalla A, Viltono L, Mackie K, Franzoni MF. Expression and distribution of CB1 cannabinoid receptors in the central nervous system of the African cichlid fish Pelvicachromis pulcher. The Journal of Comparative Neurology. 485: 293-303. PMID 15803507 DOI: 10.1002/Cne.20502 |
0.426 |
|
2005 |
Köfalvi A, Rodrigues RJ, Ledent C, Mackie K, Vizi ES, Cunha RA, Sperlágh B. Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2874-84. PMID 15772347 DOI: 10.1523/Jneurosci.4232-04.2005 |
0.415 |
|
2005 |
Benito C, Kim WK, Kim WK, ChavarrÃa I, Hillard CJ, Mackie K, Tolón RM, Williams K, Williams K, Romero J. A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2530-6. PMID 15758162 DOI: 10.1523/JNEUROSCI.3923-04.2005 |
0.367 |
|
2005 |
Kearn CS, Blake-Palmer K, Daniel E, Mackie K, Glass M. Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Molecular Pharmacology. 67: 1697-704. PMID 15710746 DOI: 10.1124/mol.104.006882 |
0.491 |
|
2004 |
Bátkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J, Offertáler L, Mackie K, Rudd MA, Bukoski RD, Kunos G. Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation. 110: 1996-2002. PMID 15451779 DOI: 10.1161/01.Cir.0000143230.23252.D2 |
0.332 |
|
2004 |
Hirasawa M, Schwab Y, Natah S, Hillard CJ, Mackie K, Sharkey KA, Pittman QJ. Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain. The Journal of Physiology. 559: 611-24. PMID 15254151 DOI: 10.1113/Jphysiol.2004.066159 |
0.63 |
|
2004 |
Pickel VM, Chan J, Kash TL, Rodríguez JJ, MacKie K. Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens. Neuroscience. 127: 101-12. PMID 15219673 DOI: 10.1016/j.neuroscience.2004.05.015 |
0.449 |
|
2004 |
Suh BC, Horowitz LF, Hirdes W, Mackie K, Hille B. Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq. The Journal of General Physiology. 123: 663-83. PMID 15173220 DOI: 10.1085/jgp.200409029 |
0.726 |
|
2004 |
Harkany T, Holmgren C, Härtig W, Qureshi T, Chaudhry FA, Storm-Mathisen J, Dobszay MB, Berghuis P, Schulte G, Sousa KM, Fremeau RT, Edwards RH, Mackie K, Ernfors P, Zilberter Y. Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4978-88. PMID 15163690 DOI: 10.1523/Jneurosci.4884-03.2004 |
0.361 |
|
2004 |
Luk T, Jin W, Zvonok A, Lu D, Lin XZ, Chavkin C, Makriyannis A, Mackie K. Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist. British Journal of Pharmacology. 142: 495-500. PMID 15148260 DOI: 10.1038/Sj.Bjp.0705792 |
0.463 |
|
2004 |
MacNaughton WK, Van Sickle MD, Keenan CM, Cushing K, Mackie K, Sharkey KA. Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G863-71. PMID 14701723 DOI: 10.1152/Ajpgi.00482.2003 |
0.641 |
|
2003 |
Harkany T, Härtig W, Berghuis P, Dobszay MB, Zilberter Y, Edwards RH, Mackie K, Ernfors P. Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons. The European Journal of Neuroscience. 18: 1979-92. PMID 14622230 DOI: 10.1046/J.1460-9568.2003.02898.X |
0.47 |
|
2003 |
Chen K, Ratzliff A, Hilgenberg L, Gulyás A, Freund TF, Smith M, Dinh TP, Piomelli D, Mackie K, Soltesz I. Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron. 39: 599-611. PMID 12925275 DOI: 10.1016/S0896-6273(03)00499-9 |
0.512 |
|
2003 |
McLaughlin JP, Xu M, Mackie K, Chavkin C. Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization. The Journal of Biological Chemistry. 278: 34631-40. PMID 12815037 DOI: 10.1074/Jbc.M304022200 |
0.473 |
|
2003 |
Van Sickle MD, Oland LD, Mackie K, Davison JS, Sharkey KA. Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G566-76. PMID 12791597 DOI: 10.1152/Ajpgi.00113.2003 |
0.606 |
|
2003 |
Walter L, Franklin A, Witting A, Wade C, Xie Y, Kunos G, Mackie K, Stella N. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1398-405. PMID 12598628 |
0.35 |
|
2003 |
Walter L, Franklin A, Witting A, Wade C, Xie Y, Kunos G, Mackie K, Stella N. Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration The Journal of Neuroscience. 23: 1398-1405. DOI: 10.1523/Jneurosci.23-04-01398.2003 |
0.458 |
|
2003 |
Macnaughton WK, Cushing K, Van Sickle MD, Keenan CM, Mackie K, Sharkey KA. Cannabinoid CB1 receptor distribution and function in neurally mediated chloride secretion in the guinea pig ileum Gastroenterology. 124: A342. DOI: 10.1016/S0016-5085(03)81726-2 |
0.592 |
|
2002 |
Wager-Miller J, Westenbroek R, Mackie K. Dimerization of G protein-coupled receptors: CB1 cannabinoid receptors as an example. Chemistry and Physics of Lipids. 121: 83-89. PMID 12505693 DOI: 10.1016/S0009-3084(02)00151-2 |
0.403 |
|
2002 |
Roche JP, Westenbroek R, Sorom AJ, Hille B, Mackie K, Shapiro MS. Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels. British Journal of Pharmacology. 137: 1173-86. PMID 12466226 DOI: 10.1038/sj.bjp.0704989 |
0.664 |
|
2002 |
Coutts AA, Irving AJ, Mackie K, Pertwee RG, Anavi-Goffer S. Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus. The Journal of Comparative Neurology. 448: 410-22. PMID 12115703 DOI: 10.1002/Cne.10270 |
0.529 |
|
2002 |
Brown SM, Wager-Miller J, Mackie K. Cloning and molecular characterization of the rat CB2 cannabinoid receptor. Biochimica Et Biophysica Acta. 1576: 255-264. PMID 12084572 DOI: 10.1016/S0167-4781(02)00341-X |
0.433 |
|
2002 |
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/Pr.54.2.161 |
0.535 |
|
2002 |
Cesa R, Guastalla A, Cottone E, Mackie K, Beltramo M, Franzoni MF. Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study. General and Comparative Endocrinology. 125: 17-24. PMID 11825030 DOI: 10.1006/Gcen.2001.7720 |
0.427 |
|
2002 |
Salio C, Fischer J, Franzoni MF, Mackie K, Kaneko T, Conrath M. CB1-cannabinoid and mu-opioid receptor co-localization on postsynaptic target in the rat dorsal horn. Neuroreport. 12: 3689-92. PMID 11726775 DOI: 10.1097/00001756-200112040-00017 |
0.384 |
|
2002 |
Hsieh C, Brown S, Derleth C, Mackie K. Internalization and Recycling of the CB1 Cannabinoid Receptor Journal of Neurochemistry. 73: 493-501. PMID 10428044 DOI: 10.1046/J.1471-4159.1999.0730493.X |
0.489 |
|
2002 |
Diana MA, Levenes C, Mackie K, Marty A. Short-Term Retrograde Inhibition of GABAergic Synaptic Currents in Rat Purkinje Cells Is Mediated by Endogenous Cannabinoids The Journal of Neuroscience. 22: 200-208. DOI: 10.1523/Jneurosci.22-01-00200.2002 |
0.39 |
|
2001 |
Cesa R, Mackie K, Beltramo M, Franzoni MF. Cannabinoid receptor CB1-like and glutamic acid decarboxylase-like immunoreactivities in the brain of Xenopus laevis Cell and Tissue Research. 306: 391-398. PMID 11735039 DOI: 10.1007/S004410100461 |
0.38 |
|
2001 |
Katona I, Rancz EA, Acsady L, Ledent C, Mackie K, Hajos N, Freund TF. Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9506-18. PMID 11717385 DOI: 10.1523/Jneurosci.21-23-09506.2001 |
0.51 |
|
2001 |
Van Sickle MD, Oland LD, Ho W, Hillard CJ, Mackie K, Davison JS, Sharkey KA. Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. Gastroenterology. 121: 767-74. PMID 11606489 DOI: 10.1053/Gast.2001.28466 |
0.605 |
|
2001 |
Rodriguez JJ, Mackie K, Pickel VM. Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 823-33. PMID 11157068 DOI: 10.1523/Jneurosci.21-03-00823.2001 |
0.392 |
|
2001 |
Coutts AA, Anavi-Goffer S, Ross RA, MacEwan DJ, Mackie K, Pertwee RG, Irving AJ. Agonist-induced internalization and trafficking of cannabinoid CB1 receptors in hippocampal neurons. The Journal of Neuroscience. 21: 2425-2433. DOI: 10.1523/Jneurosci.21-07-02425.2001 |
0.521 |
|
2001 |
Rodrı́guez JJ, Mackie K, Pickel VM. Ultrastructural Localization of the CB1 Cannabinoid Receptor in μ-Opioid Receptor Patches of the Rat Caudate Putamen Nucleus The Journal of Neuroscience. 21: 823-833. DOI: 10.1523/JNEUROSCI.21-03-00823.2001 |
0.31 |
|
2001 |
Van Sickle MD, Oland LD, Mackie K, Davison JS, Sharkey KA. Distribution of the cannabinoid 1 receptor in the brainstem and gut: A novel neuroregulatory system in emesis Gastroenterology. 120: A197. DOI: 10.1016/S0016-5085(08)80976-6 |
0.313 |
|
2000 |
Calignano A, Kátona I, Désarnaud F, Giuffrida A, La Rana G, Mackie K, Freund TF, Piomelli D. Bidirectional control of airway responsiveness by endogenous cannabinoids. Nature. 408: 96-101. PMID 11081515 DOI: 10.1038/35040576 |
0.525 |
|
2000 |
Katona I, Sperlágh B, Maglóczky Z, Sántha E, Köfalvi A, Czirják S, Mackie K, Vizi ES, Freund TF. GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus. Neuroscience. 100: 797-804. PMID 11036213 DOI: 10.1016/S0306-4522(00)00286-4 |
0.474 |
|
2000 |
Hájos N, Katona I, Naiem SS, MacKie K, Ledent C, Mody I, Freund TF. Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. The European Journal of Neuroscience. 12: 3239-49. PMID 10998107 DOI: 10.1046/J.1460-9568.2000.00217.X |
0.487 |
|
2000 |
Irving AJ, Coutts AA, Harvey J, Rae MG, Mackie K, Bewick GS, Pertwee RG. Functional expression of cell surface cannabinoid CB(1) receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons. Neuroscience. 98: 253-62. PMID 10854756 DOI: 10.1016/S0306-4522(00)00120-2 |
0.5 |
|
2000 |
Hernández M, Berrendero F, Suárez I, García-Gil L, Cebeira M, Mackie K, Ramos JA, Fernández-Ruiz J. Cannabinoid CB(1) receptors colocalize with tyrosine hydroxylase in cultured fetal mesencephalic neurons and their activation increases the levels of this enzyme. Brain Research. 857: 56-65. PMID 10700552 DOI: 10.1016/S0006-8993(99)02322-7 |
0.493 |
|
2000 |
Shapiro MS, Roche JP, Kaftan EJ, Cruzblanca H, Mackie K, Hille B. Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1710-21. PMID 10684873 DOI: 10.1523/Jneurosci.20-05-01710.2000 |
0.687 |
|
2000 |
Sañudo-Peña MC, Tsou K, Romero J, Mackie K, Walker JM. Role of the superior colliculus in the motor effects of cannabinoids and dopamine. Brain Research. 853: 207-14. PMID 10640618 DOI: 10.1016/S0006-8993(99)02291-X |
0.463 |
|
1999 |
Lu XR, Ong WY, Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in monkey basal forebrain Journal of Neurocytology. 28: 1045-1051. PMID 11054904 DOI: 10.1023/A:1007052507911 |
0.422 |
|
1999 |
Straiker A, Stella N, Piomelli D, Mackie K, Karten HJ, Maguire G. Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proceedings of the National Academy of Sciences of the United States of America. 96: 14565-70. PMID 10588745 DOI: 10.1073/Pnas.96.25.14565 |
0.813 |
|
1999 |
Ong WY, Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in the primate spinal cord. Journal of Neurocytology. 28: 39-45. PMID 10573606 DOI: 10.1023/A:1007011700677 |
0.42 |
|
1999 |
Tsou K, Mackie K, Sañudo-Peña MC, Walker JM. Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation. Neuroscience. 93: 969-75. PMID 10473261 DOI: 10.1016/S0306-4522(99)00086-X |
0.53 |
|
1999 |
Roche JP, Bounds S, Brown S, Mackie K. A mutation in the second transmembrane region of the CB1 receptor selectively disrupts G protein signaling and prevents receptor internalization Molecular Pharmacology. 56: 611-618. PMID 10462549 DOI: 10.1124/Mol.56.3.611 |
0.478 |
|
1999 |
Ong WY, Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in primate brain. Neuroscience. 92: 1177-1191. PMID 10426477 DOI: 10.1016/S0306-4522(99)00025-1 |
0.486 |
|
1999 |
Mackie K, Walker JM. Kang tsou (1932-1999) Trends in Neurosciences. 22: 331. PMID 10407414 DOI: 10.1016/S0166-2236(99)01450-2 |
0.434 |
|
1999 |
Katona I, Sperlágh B, SÃk A, Käfalvi A, Vizi ES, Mackie K, Freund TF. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4544-58. PMID 10341254 DOI: 10.1523/Jneurosci.19-11-04544.1999 |
0.427 |
|
1999 |
Jin W, Brown S, Roche JP, Hsieh C, Celver JP, Kovoor A, Chavkin C, Mackie K. Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3773-80. PMID 10234009 DOI: 10.1523/Jneurosci.19-10-03773.1999 |
0.471 |
|
1998 |
García DE, Li B, García-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca2+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9163-70. PMID 9801356 |
0.713 |
|
1998 |
Garcia DE, Brown S, Hille B, Mackie K. Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2834-41. PMID 9526000 DOI: 10.1523/Jneurosci.18-08-02834.1998 |
0.765 |
|
1998 |
Tsou K, Brown S, Sañudo-Peña MC, Mackie K, Walker JM. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience. 83: 393-411. PMID 9460749 DOI: 10.1016/S0306-4522(97)00436-3 |
0.491 |
|
1998 |
Felder CC, Joyce KE, Briley EM, Glass M, Mackie KP, Fahey KJ, Cullinan GJ, Hunden DC, Johnson DW, Chaney MO, Koppel GA, Brownstein M. LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation. The Journal of Pharmacology and Experimental Therapeutics. 284: 291-7. PMID 9435190 |
0.42 |
|
1998 |
Garcı́a DE, Li B, Garcı́a-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-Protein β-Subunit Specificity in the Fast Membrane-Delimited Inhibition of Ca2+ Channels The Journal of Neuroscience. 18: 9163-9170. DOI: 10.1523/Jneurosci.18-22-09163.1998 |
0.673 |
|
1997 |
Twitchell W, Brown S, Mackie K. Cannabinoids Inhibit N- and P/Q-Type Calcium Channels in Cultured Rat Hippocampal Neurons Journal of Neurophysiology. 78: 43-50. PMID 9242259 DOI: 10.1152/Jn.1997.78.1.43 |
0.308 |
|
1996 |
Herlitze S, Garcia DE, Mackie K, Hille B, Scheuer T, Catterall WA. Modulation of Ca2+ channels by G-protein beta gamma subunits. Nature. 380: 258-62. PMID 8637576 DOI: 10.1038/380258a0 |
0.727 |
|
1996 |
Herlitze S, Garcia DE, Mackie K, Hille B, Scheuer T, Catterall WA. Erratum: Modulation of Ca2+ channels by G-protein βγ subunits Nature. 381: 172-172. DOI: 10.1038/381172D0 |
0.677 |
|
1995 |
Mackie K, Lai Y, Westenbroek R, Mitchell R. Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor The Journal of Neuroscience. 15: 6552-6561. DOI: 10.1523/Jneurosci.15-10-06552.1995 |
0.414 |
|
1993 |
Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60. PMID 8395053 DOI: 10.1073/Pnas.90.16.7656 |
0.486 |
|
1992 |
Mackie K, Hille B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 3825-9. PMID 1315042 DOI: 10.1073/Pnas.89.9.3825 |
0.713 |
|
1991 |
Mackie K, Hille B. CANNABINOIDS INHIBIT A HIGH-THRESHHOLD CALCIUM CURRENT Anesthesiology. 75: A585-A585. DOI: 10.1097/00000542-199109001-00584 |
0.605 |
|
1989 |
Mackie KP, Nairn AC, Hampel G, Lam G, Jaffe EA. Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells. The Journal of Biological Chemistry. 264: 1748-53. PMID 2536373 |
0.419 |
|
1989 |
Mackie K, Sorkin B, Nairn A, Greengard P, Edelman G, Cunningham B. Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM The Journal of Neuroscience. 9: 1883-1896. DOI: 10.1523/Jneurosci.09-06-01883.1989 |
0.537 |
|
1986 |
Mackie K, Lai Y, Nairn AC, Greengard P, Pitt BR, Lazo JS. Protein phosphorylation in cultured endothelial cells. Journal of Cellular Physiology. 128: 367-74. PMID 3745280 DOI: 10.1002/jcp.1041280304 |
0.551 |
|
Show low-probability matches. |