Katherine Conant - Publications

Affiliations: 
Georgetown University, Washington, DC 
Area:
Neuroimmunology, MMPs

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Amontree M, Nelson M, Stefansson L, Pak D, Maguire-Zeiss K, Turner RS, Conant K. Resveratrol differentially affects MMP-9 release from neurons and glia; implications for therapeutic efficacy. Journal of Neurochemistry. PMID 38163875 DOI: 10.1111/jnc.16031  0.472
2023 Greco GA, Rock M, Amontree M, Lanfranco MF, Korthas H, Hong SH, Turner RS, Rebeck GW, Conant K. CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice. Neurobiology of Disease. 179: 106057. PMID 36878326 DOI: 10.1016/j.nbd.2023.106057  0.326
2021 Kennedy-Wood K, Ng CAS, Alaiyed S, Foley PL, Conant K. Increased MMP-9 levels with strain-dependent stress resilience and tunnel handling in mice. Behavioural Brain Research. 113288. PMID 33836170 DOI: 10.1016/j.bbr.2021.113288  0.783
2020 Blanco I, Conant K. Extracellular Matrix Remodeling with Stress and Depression: Studies in Human, Rodent, and Zebrafish Models. The European Journal of Neuroscience. PMID 32673433 DOI: 10.1111/ejn.14910  0.441
2020 Caccavano A, Bozzelli PL, Forcelli PA, Pak DTS, Wu JY, Conant K, Vicini S. Inhibitory parvalbumin basket cell activity is selectively reduced during hippocampal sharp wave ripples in a mouse model of familial Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32439703 DOI: 10.1523/Jneurosci.0425-20.2020  0.748
2020 Alaiyed S, McCann M, Mahajan G, Rajkowska G, Stockmeier CA, Kellar KJ, Wu JY, Conant K. Venlafaxine stimulates an MMP-9-dependent increase in excitatory/inhibitory balance in a stress model of depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32269106 DOI: 10.1523/Jneurosci.2387-19.2020  0.805
2019 Bozzelli PL, Caccavano A, Avdoshina V, Mocchetti I, Wu JY, Conant K. Increased matrix metalloproteinase levels and perineuronal net proteolysis in the HIV-infected brain; relevance to altered neuronal population dynamics. Experimental Neurology. 113077. PMID 31678140 DOI: 10.1016/J.Expneurol.2019.113077  0.741
2019 Alaiyed S, Conant K. A Role for Matrix Metalloproteases in Antidepressant Efficacy. Frontiers in Molecular Neuroscience. 12: 117. PMID 31133801 DOI: 10.3389/Fnmol.2019.00117  0.823
2019 Bozzelli PL, Yin T, Avdoshina V, Mocchetti I, Conant KE, Maguire-Zeiss KA. HIV-1 Tat promotes astrocytic release of CCL2 through MMP/PAR-1 signaling. Glia. PMID 31124192 DOI: 10.1002/Glia.23642  0.387
2019 Sepulveda-Rodriguez A, Li P, Khan T, Ma JD, Carlone CA, Bozzelli PL, Conant KE, Forcelli PA, Vicini S. Electroconvulsive Shock Enhances Responsive Motility and Purinergic Currents in Microglia in the Mouse Hippocampus. Eneuro. 6. PMID 31058213 DOI: 10.1523/ENEURO.0056-19.2019  0.541
2019 Alaiyed S, Bozzelli PL, Caccavano A, Wu JY, Conant K. Venlafaxine stimulates PNN proteolysis and MMP-9 dependent enhancement of gamma power; relevance to antidepressant efficacy. Journal of Neurochemistry. PMID 30697747 DOI: 10.1111/Jnc.14671  0.801
2019 Caccavano A, Bozzelli PL, Conant K, Vicini S. 3177 Determining mechanisms underlying hippocampal network disruption in early amyloid pathology Journal of Clinical and Translational Science. 3: 103-104. DOI: 10.1017/cts.2019.236  0.575
2018 Al-Muhtasib N, Forcelli PA, Conant KE, Vicini S. MMP-1 overexpression selectively alters inhibition in D1 spiny projection neurons in the mouse nucleus accumbens core. Scientific Reports. 8: 16230. PMID 30385861 DOI: 10.1038/S41598-018-34551-Z  0.649
2018 Coate TM, Conant K. Brevican "nets" voltage-gated calcium channels at the hair cell ribbon synapse. Bmc Biology. 16: 105. PMID 30253757 DOI: 10.1186/s12915-018-0575-7  0.358
2018 Jiang H, Liu S, Geng X, Caccavano A, Conant K, Vicini S, Wu J. Pacing Hippocampal Sharp-Wave Ripples With Weak Electric Stimulation. Frontiers in Neuroscience. 12: 164. PMID 29599704 DOI: 10.3389/Fnins.2018.00164  0.713
2018 Lorenzo Bozzelli P, Alaiyed S, Kim E, Villapol S, Conant K. Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics. Neural Plasticity. 2018: 5735789. PMID 29531525 DOI: 10.1155/2018/5735789  0.789
2017 Sun Z, Bozzelli PL, Caccavano A, Allen M, Balmuth J, Vicini S, Wu JY, Conant K. Disruption of perineuronal nets increases the frequency of sharp wave ripple events. Hippocampus. PMID 28921856 DOI: 10.1002/Hipo.22804  0.798
2017 Conant K, Daniele S, Bozzelli PL, Abdi T, Edwards A, Szklarczyk A, Olchefske I, Ottenheimer D, Maguire-Zeiss K. Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation. Journal of Neuroinflammation. 14: 56. PMID 28302163 DOI: 10.1186/S12974-017-0827-4  0.521
2016 Li Y, Chen X, Dzakpasu R, Conant K. Dopamine dependent effects on basal and glutamate stimulated network dynamics in cultured hippocampal neurons. Journal of Neurochemistry. PMID 27925199 DOI: 10.1111/jnc.13915  0.736
2016 Allen M, Ghosh S, Ahern GP, Villapol S, Maguire-Zeiss KA, Conant K. Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1. Scientific Reports. 6: 35497. PMID 27762280 DOI: 10.1038/Srep35497  0.797
2016 Li Y, Partridge J, Berger C, Sepulveda-Rodriguez A, Vicini S, Conant K. Dopamine increases NMDA-stimulated calcium flux in striatopallidal neurons through a matrix metalloproteinase-dependent mechanism. The European Journal of Neuroscience. 43: 194-203. PMID 26660285 DOI: 10.1111/Ejn.13146  0.666
2015 Valente MM, Allen M, Bortolotto V, Lim ST, Conant K, Grilli M. The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells. Neural Plasticity. 2015: 646595. PMID 26783471 DOI: 10.1155/2015/646595  0.819
2015 Conant K, Allen M, Lim ST. Activity dependent CAM cleavage and neurotransmission. Frontiers in Cellular Neuroscience. 9: 305. PMID 26321910 DOI: 10.3389/Fncel.2015.00305  0.753
2013 Lonskaya I, Partridge J, Lalchandani RR, Chung A, Lee T, Vicini S, Hoe HS, Lim ST, Conant K. Soluble ICAM-5, a product of activity dependent proteolysis, increases mEPSC frequency and dendritic expression of GluA1. Plos One. 8: e69136. PMID 23844251 DOI: 10.1371/Journal.Pone.0069136  0.689
2013 Niedringhaus M, Chen X, Conant K, Dzakpasu R. Synaptic potentiation facilitates memory-like attractor dynamics in cultured in vitro hippocampal networks. Plos One. 8: e57144. PMID 23526935 DOI: 10.1371/journal.pone.0057144  0.755
2012 Niedringhaus M, Chen X, Dzakpasu R, Conant K. MMPs and soluble ICAM-5 increase neuronal excitability within in vitro networks of hippocampal neurons. Plos One. 7: e42631. PMID 22912716 DOI: 10.1371/journal.pone.0042631  0.821
2012 Conant K, Lim ST, Randall B, Maguire-Zeiss KA. Matrix metalloproteinase dependent cleavage of cell adhesion molecules in the pathogenesis of CNS dysfunction with HIV and methamphetamine. Current Hiv Research. 10: 384-91. PMID 22591362 DOI: 10.2174/157016212802138733  0.572
2011 Ragin AB, Wu Y, Ochs R, Du H, Epstein LG, Conant K, McArthur JC. Marked relationship between matrix metalloproteinase 7 and brain atrophy in HIV infection. Journal of Neurovirology. 17: 153-8. PMID 21302026 DOI: 10.1007/S13365-011-0018-5  0.411
2011 Conant K, Lonskaya I, Szklarczyk A, Krall C, Steiner J, Maguire-Zeiss K, Lim ST. Methamphetamine-associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule-5. Journal of Neurochemistry. 118: 521-32. PMID 21166806 DOI: 10.1111/J.1471-4159.2010.07153.X  0.815
2010 Szklarczyk A, Conant K. Matrix metalloproteinases, synaptic injury, and multiple sclerosis. Frontiers in Psychiatry. 1: 130. PMID 21423441 DOI: 10.3389/fpsyt.2010.00130  0.417
2010 Conant K, Wang Y, Szklarczyk A, Dudak A, Mattson MP, Lim ST. Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation. Neuroscience. 166: 508-21. PMID 20045450 DOI: 10.1016/J.Neuroscience.2009.12.061  0.582
2009 Ragin AB, Wu Y, Ochs R, Scheidegger R, Cohen BA, McArthur JC, Epstein LG, Conant K. Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection. Journal of Neurovirology. 15: 275-81. PMID 19444696 DOI: 10.1080/13550280902913271  0.417
2009 Conant K, Venkatesan A, Nath A. Methamphetamine and HIV infection, role in neurocognitive dysfunction Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. 8: 184-191. DOI: 10.2174/187152309789152084  0.325
2008 Szklarczyk A, Ewaleifoh O, Beique JC, Wang Y, Knorr D, Haughey N, Malpica T, Mattson MP, Huganir R, Conant K. MMP-7 cleaves the NR1 NMDA receptor subunit and modifies NMDA receptor function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3757-67. PMID 18644839 DOI: 10.1096/Fj.07-101402  0.51
2008 Milward E, Kim KJ, Szklarczyk A, Nguyen T, Melli G, Nayak M, Deshpande D, Fitzsimmons C, Hoke A, Kerr D, Griffin JW, Calabresi PA, Conant K. Cleavage of myelin associated glycoprotein by matrix metalloproteinases. Journal of Neuroimmunology. 193: 140-8. PMID 18063113 DOI: 10.1016/J.Jneuroim.2007.11.001  0.483
2007 Szklarczyk A, Conant K, Owens DF, Ravin R, McKay RD, Gerfen C. Matrix metalloproteinase-7 modulates synaptic vesicle recycling and induces atrophy of neuronal synapses. Neuroscience. 149: 87-98. PMID 17826919 DOI: 10.1016/j.neuroscience.2007.07.032  0.579
2007 Milward EA, Fitzsimmons C, Szklarczyk A, Conant K. The matrix metalloproteinases and CNS plasticity: an overview. Journal of Neuroimmunology. 187: 9-19. PMID 17555826 DOI: 10.1016/j.jneuroim.2007.04.010  0.488
2007 Szklarczyk A, Oyler G, McKay R, Gerfen C, Conant K. Cleavage of neuronal synaptosomal-associated protein of 25 kDa by exogenous matrix metalloproteinase-7. Journal of Neurochemistry. 102: 1256-63. PMID 17472697 DOI: 10.1111/j.1471-4159.2007.04625.x  0.517
2007 Szklarczyk A, Stins M, Milward EA, Ryu H, Fitzsimmons C, Sullivan D, Conant K. Glial activation and matrix metalloproteinase release in cerebral malaria. Journal of Neurovirology. 13: 2-10. PMID 17454443 DOI: 10.1080/13550280701258084  0.338
2007 Sevigny JJ, Albert SM, McDermott MP, Schifitto G, McArthur JC, Sacktor N, Conant K, Selnes OA, Stern Y, McClernon DR, Palumbo D, Kieburtz K, Riggs G, Cohen B, Marder K, et al. An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection. Archives of Neurology. 64: 97-102. PMID 17210815 DOI: 10.1001/Archneur.64.1.97  0.316
2007 Gottschall PE, Conant K. MMPs and other matrix-degrading metalloproteinases in neurological disease Handbook of Neurochemistry and Molecular Neurobiology: Neural Protein Metabolism and Function. 565-590. DOI: 10.1007/978-0-387-30379-6_19  0.341
2006 Rumbaugh J, Turchan-Cholewo J, Galey D, St Hillaire C, Anderson C, Conant K, Nath A. Interaction of HIV Tat and matrix metalloproteinase in HIV neuropathogenesis: a new host defense mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1736-8. PMID 16807369 DOI: 10.1096/fj.05-5619fje  0.504
2006 Turchan-Cholewo J, Liu Y, Gartner S, Reid R, Jie C, Peng X, Chen KC, Chauhan A, Haughey N, Cutler R, Mattson MP, Pardo C, Conant K, Sacktor N, McArthur JC, et al. Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl. Neurobiology of Disease. 23: 109-19. PMID 16697650 DOI: 10.1016/J.Nbd.2006.02.005  0.34
2006 Wang T, Allie R, Conant K, Haughey N, Turchan-Chelowo J, Hahn K, Rosen A, Steiner J, Keswani S, Jones M, Calabresi PA, Nath A. Granzyme B mediates neurotoxicity through a G-protein-coupled receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1209-11. PMID 16636104 DOI: 10.1096/Fj.05-5022Fje  0.348
2006 Larsen PH, DaSilva AG, Conant K, Yong VW. Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2207-14. PMID 16495447 DOI: 10.1523/Jneurosci.1880-05.2006  0.464
2005 St Hillaire C, Vargas D, Pardo CA, Gincel D, Mann J, Rothstein JD, McArthur JC, Conant K. Aquaporin 4 is increased in association with human immunodeficiency virus dementia: implications for disease pathogenesis. Journal of Neurovirology. 11: 535-43. PMID 16338747 DOI: 10.1080/13550280500385203  0.347
2004 Heine W, Conant K, Griffin JW, Höke A. Transplanted neural stem cells promote axonal regeneration through chronically denervated peripheral nerves. Experimental Neurology. 189: 231-40. PMID 15380475 DOI: 10.1016/J.Expneurol.2004.06.014  0.323
2004 Bilak M, Wu L, Wang Q, Haughey N, Conant K, St Hillaire C, Andreasson K. PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis. Annals of Neurology. 56: 240-8. PMID 15293276 DOI: 10.1002/Ana.20179  0.352
2004 Conant K, St Hillaire C, Anderson C, Galey D, Wang J, Nath A. Human immunodeficiency virus type 1 Tat and methamphetamine affect the release and activation of matrix-degrading proteinases. Journal of Neurovirology. 10: 21-8. PMID 14982725 DOI: 10.1080/13550280490261699  0.506
2004 Conant K, St Hillaire C, Nagase H, Visse R, Gary D, Haughey N, Anderson C, Turchan J, Nath A. Matrix metalloproteinase 1 interacts with neuronal integrins and stimulates dephosphorylation of Akt. The Journal of Biological Chemistry. 279: 8056-62. PMID 14679206 DOI: 10.1074/Jbc.M307051200  0.534
2002 Volpert OV, Pili R, Sikder HA, Nelius T, Zaichuk T, Morris C, Shiflett CB, Devlin MK, Conant K, Alani RM. Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell. 2: 473-83. PMID 12498716 DOI: 10.1016/S1535-6108(02)00209-X  0.302
2002 Conant K, Haughey N, Nath A, St Hillaire C, Gary DS, Pardo CA, Wahl LM, Bilak M, Milward E, Mattson MP. Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9. Journal of Neurochemistry. 82: 885-93. PMID 12358794 DOI: 10.1046/J.1471-4159.2002.01038.X  0.485
2001 Vawter MP, Usen N, Thatcher L, Ladenheim B, Zhang P, VanderPutten DM, Conant K, Herman MM, van Kammen DP, Sedvall G, Garver DL, Freed WJ. Characterization of human cleaved N-CAM and association with schizophrenia. Experimental Neurology. 172: 29-46. PMID 11681838 DOI: 10.1006/exnr.2001.7790  0.315
2001 Johnston JB, Zhang K, Silva C, Shalinsky DR, Conant K, Ni W, Corbett D, Yong VW, Power C. HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors. Annals of Neurology. 49: 230-41. PMID 11220743 DOI: 10.1002/1531-8249(20010201)49:2<230::Aid-Ana43>3.0.Co;2-O  0.529
2000 Vos CM, Gartner S, Ransohoff RM, McArthur JC, Wahl L, Sjulson L, Hunter E, Conant K. Matrix metalloprotease-9 release from monocytes increases as a function of differentiation: implications for neuroinflammation and neurodegeneration. Journal of Neuroimmunology. 109: 221-7. PMID 10996224 DOI: 10.1016/S0165-5728(00)00308-8  0.784
2000 Vos CM, Sjulson L, Nath A, McArthur JC, Pardo CA, Rothstein J, Conant K. Cytotoxicity by matrix metalloprotease-1 in organotypic spinal cord and dissociated neuronal cultures. Experimental Neurology. 163: 324-30. PMID 10833306 DOI: 10.1006/Exnr.2000.7388  0.797
1999 Conant K, McArthur JC, Griffin DE, Sjulson L, Wahl LM, Irani DN. Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia. Annals of Neurology. 46: 391-8. PMID 10482270 DOI: 10.1002/1531-8249(199909)46:3<391::Aid-Ana15>3.0.Co;2-0  0.798
1999 Nath A, Conant K, Chen P, Scott C, Major EO. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon. The Journal of Biological Chemistry. 274: 17098-102. PMID 10358063 DOI: 10.1074/Jbc.274.24.17098  0.472
1998 Conant K, Ahmed U, Schwartz JP, Major EO. IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism. Journal of Neuroimmunology. 88: 39-44. PMID 9688322 DOI: 10.1016/S0165-5728(98)00069-1  0.47
1998 Conant K, Garzino-Demo A, Nath A, McArthur JC, Halliday W, Power C, Gallo RC, Major EO. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 3117-21. PMID 9501225 DOI: 10.1073/Pnas.95.6.3117  0.491
1996 Conant K, Ma M, Nath A, Major EO. Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes. Journal of Virology. 70: 1384-9. PMID 8627654 DOI: 10.1128/Jvi.70.3.1384-1389.1996  0.537
1995 Tomatore C, Conant K, Atwood W, Major E. Characterization of the natural history of HIV-1 infection of astrocytes in the developing pediatric nervous system Journal of Neuroimmunology. 63: 99. DOI: 10.1016/0165-5728(96)80982-9  0.452
1994 Tornatore C, Meyers K, Atwood W, Conant K, Major E. Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. Journal of Virology. 68: 93-102. PMID 8254781 DOI: 10.1128/Jvi.68.1.93-102.1994  0.479
1994 Conant K, Atwood WJ, Traub R, Tornatore C, Major EO. An increase in p50/p65 NF-kB binding to the HIV-1 LTR is not sufficient to increase viral expression in the primary human astrocyte. Virology. 205: 586-90. PMID 7975262 DOI: 10.1006/Viro.1994.1685  0.487
1994 Conant K, Tornatore C, Atwood W, Meyers K, Traub R, Major EO. In vivo and in vitro infection of the astrocyte by HIV-1. Advances in Neuroimmunology. 4: 287-9. PMID 7874397 DOI: 10.1016/S0960-5428(06)80269-X  0.454
1994 Atwood WJ, Tornatore CS, Traub R, Conant K, Drew PD, Major EO. Stimulation of HIV type 1 gene expression and induction of NF-kappa B (p50/p65)-binding activity in tumor necrosis factor alpha-treated human fetal glial cells. Aids Research and Human Retroviruses. 10: 1207-11. PMID 7848678 DOI: 10.1089/Aid.1994.10.1207  0.474
1994 Tornatore C, Amemiya K, Atwood W, Conant K, Major EO, Berger J. JC virus: Current concepts and controversies in the molecular virology and pathogenesis of progressive multifocal leucoencephalopathy Reviews in Medical Virology. 4: 197-219. DOI: 10.1002/rmv.1980040306  0.411
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