Eugene O. Major - Publications

Affiliations: 
National Institutes of Health, Bethesda, MD 

200 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zerbe CS, Marciano BE, Katial RK, Santos CB, Adamo N, Hsu AP, Hanks ME, Darnell DN, Quesado MM, Frein C, Barnhart LA, Anderson VL, Uzel G, Freeman AF, Lisco A, ... ... Major EO, et al. Progressive Multifocal Leukencephalopathy in Primary Immune Deficiencies: STAT1 Gain of Function and Review of the Literature. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26743090 DOI: 10.1093/cid/civ1220  0.4
2015 Patera AC, Butler SL, Cinque P, Clifford DB, Elston R, Garcea RL, Major EO, Pavlovic D, Peterson IS, Ryan AM, Tyler KL, Weber T. 2nd International Conference on Progressive Multifocal Leukoencephalopathy (PML) 2015: JCV virology, progressive multifocal leukoencephalopathy pathogenesis, diagnosis and risk stratification, and new approaches to prevention and treatment. Journal of Neurovirology. PMID 26501778 DOI: 10.1007/s13365-015-0392-5  0.4
2015 Li GH, Anderson C, Jaeger L, Do T, Major EO, Nath A. Cell-to-cell contact facilitates HIV transmission from lymphocytes to astrocytes via CXCR4. Aids (London, England). 29: 755-66. PMID 25985398 DOI: 10.1097/QAD.0000000000000605  0.4
2015 Monaco MC, Major EO. Immune System Involvement in the Pathogenesis of JC Virus Induced PML: What is Learned from Studies of Patients with Underlying Diseases and Therapies as Risk Factors. Frontiers in Immunology. 6: 159. PMID 25972864 DOI: 10.3389/fimmu.2015.00159  0.4
2015 Wang T, Choi E, Monaco MC, Major EO, Medynets M, Nath A. Direct induction of human neural stem cells from peripheral blood hematopoietic progenitor cells. Journal of Visualized Experiments : Jove. 52298. PMID 25650990 DOI: 10.3791/52298  0.4
2015 Van Loy T, Thys K, Ryschkewitsch C, Lagatie O, Monaco MC, Major EO, Tritsmans L, Stuyver LJ. JC virus quasispecies analysis reveals a complex viral population underlying progressive multifocal leukoencephalopathy and supports viral dissemination via the hematogenous route. Journal of Virology. 89: 1340-7. PMID 25392214 DOI: 10.1128/JVI.02565-14  0.4
2014 Ferenczy MW, Major EO. Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American Type Culture Collection. Journal of Virology. 88: 12928-9. PMID 25288626 DOI: 10.1128/JVI.01600-14  0.4
2014 Frohman EM, Douek D, Major EO. Relevance of CD34+ cells as a reservoir for JC virus in patients with multiple sclerosis--reply. Jama Neurology. 71: 1192-3. PMID 25200546 DOI: 10.1001/jamaneurol.2014.1858  0.4
2014 Warnke C, von Geldern G, Markwerth P, Dehmel T, Hoepner R, Gold R, Pawlita M, Kümpfel T, Mäurer M, Stangel M, Wegner F, Hohlfeld R, Straeten V, Limmroth V, Weber T, ... ... Major E, et al. Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy. Annals of Neurology. 76: 792-801. PMID 24729444 DOI: 10.1002/ana.24153  0.4
2014 Frohman EM, Monaco MC, Remington G, Ryschkewitsch C, Jensen PN, Johnson K, Perkins M, Liebner J, Greenberg B, Monson N, Frohman TC, Douek D, Major EO. JC virus in CD34+ and CD19+ cells in patients with multiple sclerosis treated with natalizumab. Jama Neurology. 71: 596-602. PMID 24664166 DOI: 10.1001/jamaneurol.2014.63  0.4
2014 Stoppe M, Thomä E, Liebert UG, Major EO, Hoffmann KT, Claßen J, Then Bergh F. Cerebellar manifestation of PML under fumarate and after efalizumab treatment of psoriasis. Journal of Neurology. 261: 1021-4. PMID 24638202 DOI: 10.1007/s00415-014-7311-1  0.4
2014 Marshall LJ, Ferenczy MW, Daley EL, Jensen PN, Ryschkewitsch CF, Major EO. Lymphocyte gene expression and JC virus noncoding control region sequences are linked with the risk of progressive multifocal leukoencephalopathy. Journal of Virology. 88: 5177-83. PMID 24554653 DOI: 10.1128/JVI.03221-13  0.4
2014 Von Geldern G, Barhams MJ, Major EO. The biology and clinical consequence of infection with the human polyomavirus JCV Neuroinflammation and Neurodegeneration. 337-354. DOI: 10.1007/978-1-4939-1071-7_16  0.4
2013 Wang T, Choi E, Monaco MC, Campanac E, Medynets M, Do T, Rao P, Johnson KR, Elkahloun AG, Von Geldern G, Johnson T, Subramaniam S, Hoffman D, Major E, Nath A. Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation. Plos One. 8: e81720. PMID 24303066 DOI: 10.1371/journal.pone.0081720  0.4
2013 Major EO, Douek DC, Frohman EM, Walsh DR. Two demyelinating diseases in the brain of a single patient, PML and MS: how to minimize 'one' while treating the 'other'. Expert Review of Clinical Immunology. 9: 887-90. PMID 24128152 DOI: 10.1586/1744666X.2013.841559  0.4
2013 Major EO, Frohman E, Douek D. More on JC viremia in natalizumab-treated patients with multiple sclerosis. The New England Journal of Medicine. 369: 1280. PMID 24066761 DOI: 10.1056/NEJMc1308784  0.4
2013 Ferenczy MW, Johnson KR, Steinberg SM, Marshall LJ, Monaco MC, Beschloss AM, Jensen PN, Major EO. Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1303-19. PMID 24052414 DOI: 10.1007/s11481-013-9499-8  0.4
2013 Major EO, Douek DC. Risk factors for rare diseases can be risky to define: PML and natalizumab. Neurology. 81: 858-9. PMID 23925759 DOI: 10.1212/WNL.0b013e3182a352a6  0.4
2013 Major EO, Frohman E, Douek D. JC viremia in natalizumab-treated patients with multiple sclerosis. The New England Journal of Medicine. 368: 2240-1. PMID 23738566 DOI: 10.1056/NEJMc1214233  0.4
2013 Ryschkewitsch CF, Jensen PN, Major EO. Multiplex qPCR assay for ultra sensitive detection of JCV DNA with simultaneous identification of genotypes that discriminates non-virulent from virulent variants. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 57: 243-8. PMID 23619054 DOI: 10.1016/j.jcv.2013.03.009  0.4
2013 Berger JR, Aksamit AJ, Clifford DB, Davis L, Koralnik IJ, Sejvar JJ, Bartt R, Major EO, Nath A. PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section. Neurology. 80: 1430-8. PMID 23568998 DOI: 10.1212/WNL.0b013e31828c2fa1  0.4
2013 Brew BJ, McLean CA, Major EO. Progressive multifocal leukoencephalopathy caused by BK virus? The Medical Journal of Australia. 198: 179-80. PMID 23451948 DOI: 10.5694/mja12.11798  0.4
2013 Havla J, Berthele A, Kümpfel T, Krumbholz M, Jochim A, Kronsbein H, Ryschkewitsch C, Jensen P, Lippmann K, Hemmer B, Major E, Hohlfeld R. Co-occurrence of two cases of progressive multifocal leukoencephalopathy in a natalizumab "infusion group". Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1213-5. PMID 23124790 DOI: 10.1177/1352458512466165  0.4
2012 Monaco MC, Maric D, Bandeian A, Leibovitch E, Yang W, Major EO. Progenitor-derived oligodendrocyte culture system from human fetal brain. Journal of Visualized Experiments : Jove. PMID 23288248 DOI: 10.3791/4274  0.4
2012 Henderson LJ, Sharma A, Monaco MC, Major EO, Al-Harthi L. Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription through its intact core and cysteine-rich domains inhibits Wnt/β-catenin signaling in astrocytes: relevance to HIV neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16306-13. PMID 23152614 DOI: 10.1523/JNEUROSCI.3145-12.2012  0.4
2012 Perkins MR, Ryschkewitsch C, Liebner JC, Monaco MC, Himelfarb D, Ireland S, Roque A, Edward HL, Jensen PN, Remington G, Abraham T, Abraham J, Greenberg B, Kaufman C, LaGanke C, ... ... Major EO, et al. Changes in JC virus-specific T cell responses during natalizumab treatment and in natalizumab-associated progressive multifocal leukoencephalopathy. Plos Pathogens. 8: e1003014. PMID 23144619 DOI: 10.1371/journal.ppat.1003014  0.4
2012 Hellwig K, Kleiter I, Gold R. Immune reconstitution inflammatory syndrome in natalizumab-associated PML. Neurology. 78: 371; author reply 37. PMID 22291067 DOI: 10.1212/01.wnl.0000411451.56205.c3  0.4
2012 Major EO, Nath A. Neurological infections: risks of globalisation and new drugs. The Lancet. Neurology. 11: 14-5. PMID 22172615 DOI: 10.1016/S1474-4422(11)70279-4  0.4
2012 Matos A, Duque V, Luxo C, Meliço-Silvestre A, Major EO. Individuals infected with JC polyomavirus do not present detectable JC virus DNA in oropharyngeal fluids. The Journal of General Virology. 93: 692-7. PMID 22158878 DOI: 10.1099/vir.0.036798-0  0.4
2012 Monaco MC, Major EO. The link between VLA-4 and JC virus reactivation. Expert Review of Clinical Immunology. 8: 63-72. PMID 22149341 DOI: 10.1586/eci.11.85  0.4
2012 Marshall LJ, Moore LD, Mirsky MM, Major EO. JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes. The Journal of General Virology. 93: 651-61. PMID 22071512 DOI: 10.1099/vir.0.035832-0  0.4
2011 Major EO. History and current concepts in the pathogenesis of PML. Cleveland Clinic Journal of Medicine. 78: S3-7. PMID 22123932 DOI: 10.3949/ccjm.78.s2.02  0.4
2011 Kuhle J, Gosert R, Bühler R, Derfuss T, Sutter R, Yaldizli O, Radue EW, Ryschkewitsch C, Major EO, Kappos L, Frank S, Hirsch HH. Management and outcome of CSF-JC virus PCR-negative PML in a natalizumab-treated patient with MS. Neurology. 77: 2010-6. PMID 22076540 DOI: 10.1212/WNL.0b013e31823b9b27  0.4
2011 Ravichandran V, Major EO, Ibe C, Monaco MC, Girisetty MK, Hewlett IK. Susceptibility of human primary neuronal cells to xenotropic murine leukemia virus-related (XMRV) virus infection. Virology Journal. 8: 443. PMID 21933387 DOI: 10.1186/1743-422X-8-443  0.4
2011 Tan IL, McArthur JC, Clifford DB, Major EO, Nath A. Immune reconstitution inflammatory syndrome in natalizumab-associated PML. Neurology. 77: 1061-7. PMID 21832229 DOI: 10.1212/WNL.0b013e31822e55e7  0.4
2011 Kappos L, Bates D, Edan G, Eraksoy M, Garcia-Merino A, Grigoriadis N, Hartung HP, Havrdová E, Hillert J, Hohlfeld R, Kremenchutzky M, Lyon-Caen O, Miller A, Pozzilli C, Ravnborg M, ... ... Major EO, et al. Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring. The Lancet. Neurology. 10: 745-58. PMID 21777829 DOI: 10.1016/S1474-4422(11)70149-1  0.4
2011 Johne R, Buck CB, Allander T, Atwood WJ, Garcea RL, Imperiale MJ, Major EO, Ramqvist T, Norkin LC. Taxonomical developments in the family Polyomaviridae. Archives of Virology. 156: 1627-34. PMID 21562881 DOI: 10.1007/s00705-011-1008-x  0.4
2011 Li W, Henderson LJ, Major EO, Al-Harthi L. IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 186: 6771-8. PMID 21562161 DOI: 10.4049/jimmunol.1100099  0.4
2011 Cheng XS, Bohl DL, Storch GA, Ryschkewitsch C, Gaudreault-Keener M, Major EO, Randhawa P, Hardinger KL, Brennan DC. Inhibitory interactions between BK and JC virus among kidney transplant recipients. Journal of the American Society of Nephrology : Jasn. 22: 825-31. PMID 21511831 DOI: 10.1681/ASN.2010080877  0.4
2011 Gosert R, Rinaldo CH, Wernli M, Major EO, Hirsch HH. CMX001 (1-O-hexadecyloxypropyl-cidofovir) inhibits polyomavirus JC replication in human brain progenitor-derived astrocytes. Antimicrobial Agents and Chemotherapy. 55: 2129-36. PMID 21402853 DOI: 10.1128/AAC.00046-11  0.4
2011 Major EO, Ryschkewitsch CF, Jensen PN, Monaco MC. Reply: To PMID 21246607. Annals of Neurology. 69: 430-1. PMID 21387394 DOI: 10.1002/ana.22364  0.4
2011 Eugenin EA, King JE, Hazleton JE, Major EO, Bennett MV, Zukin RS, Berman JW. Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity. Neurotoxicity Research. 19: 138-48. PMID 20094923 DOI: 10.1007/s12640-010-9150-x  0.4
2010 Marshall LJ, Dunham L, Major EO. Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity. The Journal of General Virology. 91: 3042-52. PMID 20826618 DOI: 10.1099/vir.0.023184-0  0.4
2010 Jiang ZG, Cohen J, Marshall LJ, Major EO. Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures. Antimicrobial Agents and Chemotherapy. 54: 4723-32. PMID 20823288 DOI: 10.1128/AAC.00837-10  0.4
2010 Ryschkewitsch CF, Jensen PN, Monaco MC, Major EO. JC virus persistence following progressive multifocal leukoencephalopathy in multiple sclerosis patients treated with natalizumab. Annals of Neurology. 68: 384-91. PMID 20818792 DOI: 10.1002/ana.22137  0.4
2010 Gosert R, Kardas P, Major EO, Hirsch HH. Rearranged JC virus noncoding control regions found in progressive multifocal leukoencephalopathy patient samples increase virus early gene expression and replication rate. Journal of Virology. 84: 10448-56. PMID 20686041 DOI: 10.1128/JVI.00614-10  0.4
2010 Marshall LJ, Major EO. Molecular regulation of JC virus tropism: insights into potential therapeutic targets for progressive multifocal leukoencephalopathy. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 404-17. PMID 20401541 DOI: 10.1007/s11481-010-9203-1  0.4
2010 Matos A, Duque V, Beato S, da Silva JP, Major E, Meliço-Silvestre A. Characterization of JC human polyomavirus infection in a Portuguese population. Journal of Medical Virology. 82: 494-504. PMID 20087944 DOI: 10.1002/jmv.21710  0.4
2010 Major EO. Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapies. Annual Review of Medicine. 61: 35-47. PMID 19719397 DOI: 10.1146/annurev.med.080708.082655  0.4
2009 Berger JR, Houff SA, Major EO. Monoclonal antibodies and progressive multifocal leukoencephalopathy. Mabs. 1: 583-9. PMID 20073129 DOI: 10.4161/mabs.1.6.9884  0.4
2009 LindÃ¥ H, von Heijne A, Major EO, Ryschkewitsch C, Berg J, Olsson T, Martin C. Progressive multifocal leukoencephalopathy after natalizumab monotherapy. The New England Journal of Medicine. 361: 1081-7. PMID 19741229 DOI: 10.1056/NEJMoa0810316  0.4
2009 Major EO. Reemergence of PML in natalizumab-treated patients--new cases, same concerns. The New England Journal of Medicine. 361: 1041-3. PMID 19741226 DOI: 10.1056/NEJMp0906248  0.4
2009 Carson KR, Focosi D, Major EO, Petrini M, Richey EA, West DP, Bennett CL. Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project. The Lancet. Oncology. 10: 816-24. PMID 19647202 DOI: 10.1016/S1470-2045(09)70161-5  0.4
2009 Joseph J, Clifford D, Douglas SD, Fox H, Gendelman HE, Gonzalez-Scarano F, Grant I, Major E, McArthur J. Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 283-97. PMID 19455426 DOI: 10.1007/s11481-009-9159-1  0.4
2009 Carson KR, Evens AM, Richey EA, Habermann TM, Focosi D, Seymour JF, Laubach J, Bawn SD, Gordon LI, Winter JN, Furman RR, Vose JM, Zelenetz AD, Mamtani R, Raisch DW, ... ... Major EO, et al. Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project. Blood. 113: 4834-40. PMID 19264918 DOI: 10.1182/blood-2008-10-186999  0.4
2009 Lamba S, Ravichandran V, Major EO. Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism. Glia. 57: 971-7. PMID 19062179 DOI: 10.1002/glia.20821  0.4
2009 Bachis A, Biggio F, Major EO, Mocchetti I. M- and T-tropic HIVs promote apoptosis in rat neurons. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 150-60. PMID 19034668 DOI: 10.1007/s11481-008-9141-3  0.4
2009 Iacobaeus E, Ryschkewitsch C, Gravell M, Khademi M, Wallstrom E, Olsson T, Brundin L, Major EO. Analysis of cerebrospinal fluid and cerebrospinal fluid cells from patients with multiple sclerosis for detection of JC virus DNA Multiple Sclerosis. 15: 28-35. PMID 18805840 DOI: 10.1177/1352458508096870  0.4
2008 Houff SA, Berger J, Major EO. Response to Linberg et al. Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients. Journal of Neuroimmunology. 204: 155-6; author reply . PMID 19117088 DOI: 10.1016/j.jneuroim.2008.05.007  0.4
2008 Landry ML, Eid T, Bannykh S, Major E. False negative PCR despite high levels of JC virus DNA in spinal fluid: Implications for diagnostic testing. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 43: 247-9. PMID 18701345 DOI: 10.1016/j.jcv.2008.07.003  0.4
2008 Bohl DL, Brennan DC, Ryschkewitsch C, Gaudreault-Keener M, Major EO, Storch GA. BK virus antibody titers and intensity of infections after renal transplantation. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 43: 184-9. PMID 18676176 DOI: 10.1016/j.jcv.2008.06.009  0.4
2008 Ravichandran V, Major EO. DNA-binding transcription factor NF-1A negatively regulates JC virus multiplication. The Journal of General Virology. 89: 1396-401. PMID 18474555 DOI: 10.1099/vir.0.2008/000059-0  0.4
2007 Houff SA, Major EO. Neuropharmacology of HIV/AIDS. Handbook of Clinical Neurology. 85: 319-64. PMID 18808990 DOI: 10.1016/S0072-9752(07)85019-6  0.4
2007 Schwartz L, Civitello L, Dunn-Pirio A, Ryschkewitsch S, Berry E, Cavert W, Kinzel N, Lawrence DM, Hazra R, Major EO. Evidence of human immunodeficiency virus type 1 infection of nestin-positive neural progenitors in archival pediatric brain tissue. Journal of Neurovirology. 13: 274-83. PMID 17613718 DOI: 10.1080/13550280701344975  0.4
2007 Kappos L, Bates D, Hartung HP, Havrdova E, Miller D, Polman CH, Ravnborg M, Hauser SL, Rudick RA, Weiner HL, O'Connor PW, King J, Radue EW, Yousry T, Major EO, et al. Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring. The Lancet. Neurology. 6: 431-41. PMID 17434098 DOI: 10.1016/S1474-4422(07)70078-9  0.4
2007 Ravichandran V, Jensen PN, Major EO. MEK1/2 inhibitors block basal and transforming growth factor 1beta1-stimulated JC virus multiplication. Journal of Virology. 81: 6412-8. PMID 17409139 DOI: 10.1128/JVI.02658-06  0.4
2007 Roseti L, Facchini A, De Franceschi L, Marconi E, Major EO, Grigolo B. Induction of original phenotype of human immortalized chondrocytes: a quantitative gene expression analysis. International Journal of Molecular Medicine. 19: 89-96. PMID 17143552  0.4
2006 Berman JW, Carson MJ, Chang L, Cox BM, Fox HS, Gonzalez RG, Hanson GR, Hauser KF, Ho WZ, Hong JS, Major EO, Maragos WF, Masliah E, McArthur JC, Miller DB, et al. NeuroAIDS, drug abuse, and inflammation: building collaborative research activities. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 351-99. PMID 18040811 DOI: 10.1007/s11481-006-9048-9  0.4
2006 Ahlqvist J, Donati D, Martinelli E, Akhyani N, Hou J, Major EO, Jacobson S, Fogdell-Hahn A. Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A in astrocytes and in T-cells. Journal of Medical Virology. 78: 1542-53. PMID 17063514 DOI: 10.1002/jmv.20737  0.4
2006 Ravichandran V, Major EO. Viral proteomics: a promising approach for understanding JC virus tropism. Proteomics. 6: 5628-36. PMID 16991198 DOI: 10.1002/pmic.200600261  0.4
2006 Li J, Melenhorst J, Hensel N, Rezvani K, Sconocchia G, Kilical Y, Hou J, Curfman B, Major E, Barrett AJ. T-cell responses to peptide fragments of the BK virus T antigen: implications for cross-reactivity of immune response to JC virus. The Journal of General Virology. 87: 2951-60. PMID 16963754 DOI: 10.1099/vir.0.82094-0  0.4
2006 Ravichandran V, Sabath BF, Jensen PN, Houff SA, Major EO. Interactions between c-Jun, nuclear factor 1, and JC virus promoter sequences: implications for viral tropism. Journal of Virology. 80: 10506-13. PMID 16928756 DOI: 10.1128/JVI.01355-06  0.4
2006 Schwartz L, Major EO. Neural progenitors and HIV-1-associated central nervous system disease in adults and children. Current Hiv Research. 4: 319-27. PMID 16842084 DOI: 10.2174/157016206777709438  0.4
2006 Hou J, Seth P, Major EO. JC virus can infect human immune and nervous system progenitor cells: implications for pathogenesis. Advances in Experimental Medicine and Biology. 577: 266-73. PMID 16626042 DOI: 10.1007/0-387-32957-9_19  0.4
2006 Yousry TA, Major EO, Ryschkewitsch C, Fahle G, Fischer S, Hou J, Curfman B, Miszkiel K, Mueller-Lenke N, Sanchez E, Barkhof F, Radue EW, Jäger HR, Clifford DB. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. The New England Journal of Medicine. 354: 924-33. PMID 16510746 DOI: 10.1056/NEJMoa054693  0.4
2006 Lubensky IA, Vortmeyer AO, Kim S, Lonser RR, Park DM, Ikejiri B, Li J, Okamoto H, Walbridge S, Ryschkewitsch C, Major E, Oldfield EH, Zhuang Z. Identification of tumor precursor cells in the brains of primates with radiation-induced de novo glioblastoma multiforme. Cell Cycle (Georgetown, Tex.). 5: 452-6. PMID 16479164  0.4
2006 Nath A, Venkataramana A, Reich DS, Cortese I, Major EO. Progression of progressive multifocal leukoencephalopathy despite treatment with beta-interferon. Neurology. 66: 149-50. PMID 16401874 DOI: 10.1212/01.wnl.0000191322.93310.a1  0.4
2006 Lawrence DM, Seth P, Durham L, Diaz F, Boursiquot R, Ransohoff RM, Major EO. Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells. Glia. 53: 81-91. PMID 16206198 DOI: 10.1002/glia.20261  0.4
2006 Frank SA, Kieburtz K, Holloway R, Kim SYH. Reply from the authors [12] Neurology. 66: 1788-1789. DOI: 10.1212/01.wnl.0000230564.67320.b1  0.4
2006 Major EO, Yousry TA, Clifford DB. Dr. Yousry and colleagues reply [5] New England Journal of Medicine. 354: 2388-2389.  0.4
2005 Mannon RB, Hoffmann SC, Kampen RL, Cheng OC, Kleiner DE, Ryschkewitsch C, Curfman B, Major E, Hale DA, Kirk AD. Molecular evaluation of BK polyomavirus nephropathy American Journal of Transplantation. 5: 2883-2893. PMID 16303001 DOI: 10.1111/j.1600-6143.2005.01096.x  0.4
2005 Seth P, Major EO. Human brain derived cell culture models of HIV-1 infection. Neurotoxicity Research. 8: 83-9. PMID 16260387 DOI: 10.1007/BF03033821  0.4
2005 Hou J, Major E. Management of infections by the human polyomavirus JC: Past, present and future Expert Review of Anti-Infective Therapy. 3: 629-640. PMID 16107201 DOI: 10.1586/14787210.3.4.629  0.4
2005 Bohl DL, Storch GA, Ryschkewitsch C, Gaudreault-Keener M, Schnitzler MA, Major EO, Brennan DC. Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 2213-21. PMID 16095500 DOI: 10.1111/j.1600-6143.2005.01000.x  0.4
2005 Donati D, Martinelli E, Cassiani-Ingoni R, Ahlqvist J, Hou J, Major EO, Jacobson S. Variant-specific tropism of human herpesvirus 6 in human astrocytes. Journal of Virology. 79: 9439-48. PMID 16014907 DOI: 10.1128/JVI.79.15.9439-9448.2005  0.4
2005 Nicola AV, Hou J, Major EO, Straus SE. Herpes simplex virus type 1 enters human epidermal keratinocytes, but not neurons, via a pH-dependent endocytic pathway. Journal of Virology. 79: 7609-16. PMID 15919913 DOI: 10.1128/JVI.79.12.7609-7616.2005  0.4
2005 Gordon J, Del Valle L, Croul S, Reiss K, White M, Khalili K. Re: Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories by Rollison et al. (published online 21 October 2004). International Journal of Cancer. Journal International Du Cancer. 117: 693-4; author reply . PMID 15912533 DOI: 10.1002/ijc.21161  0.4
2005 Rollison DE, Utaipat U, Ryschkewitsch C, Hou J, Goldthwaite P, Daniel R, Helzlsouer KJ, Burger PC, Shah KV, Major EO. Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories. International Journal of Cancer. Journal International Du Cancer. 113: 769-74. PMID 15499616 DOI: 10.1002/ijc.20641  0.4
2004 Royal W, Leander M, Chen YE, Major EO, Bissonnette RP. Nuclear receptor activation and interaction with morphine. Journal of Neuroimmunology. 157: 61-5. PMID 15579281 DOI: 10.1016/j.jneuroim.2004.08.023  0.4
2004 Janabi N, Jensen PN, Major EO. Differential effects of interferon-gamma on the expression of cyclooxygenase-2 in high-grade human gliomas versus primary astrocytes. Journal of Neuroimmunology. 156: 113-22. PMID 15465602 DOI: 10.1016/j.jneuroim.2004.07.012  0.4
2004 Ryschkewitsch C, Jensen P, Hou J, Fahle G, Fischer S, Major EO. Comparison of PCR-southern hybridization and quantitative real-time PCR for the detection of JC and BK viral nucleotide sequences in urine and cerebrospinal fluid. Journal of Virological Methods. 121: 217-21. PMID 15381359 DOI: 10.1016/j.jviromet.2004.06.021  0.4
2004 Lawrence DM, Durham LC, Schwartz L, Seth P, Maric D, Major EO. Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells. Journal of Virology. 78: 7319-28. PMID 15220405 DOI: 10.1128/JVI.78.14.7319-7328.2004  0.4
2004 Seth P, Diaz F, Tao-Cheng JH, Major EO. JC virus induces nonapoptotic cell death of human central nervous system progenitor cell-derived astrocytes. Journal of Virology. 78: 4884-91. PMID 15078969 DOI: 10.1128/JVI.78.9.4884-4891.2004  0.4
2004 Buch S, Sui Y, Potula R, Pinson D, Adany I, Li Z, Huang M, Li S, Dhillon N, Major E, Narayan O. Role of interleukin-4 and monocyte chemoattractant protein-1 in the neuropathogenesis of X4 simian human immunodeficiency virus infection in macaques. Journal of Neurovirology. 10: 118-24. PMID 14982750 DOI: 10.1080/13550280490270798  0.4
2003 Roseti L, Grigolo B, Neri S, De Franceschi L, Jensen P, Major EO, Facchini A. Establishment of a new human immortalized chondrocyte cell line. La Chirurgia Degli Organi Di Movimento. 88: 357-62. PMID 15259551  0.4
2003 D'Costa J, Harvey-White J, Qasba P, Limaye A, Kaneski CR, Davis-Warren A, Brady RO, Bankiewicz KS, Major EO, Arya SK. HIV-2 derived lentiviral vectors: gene transfer in Parkinson's and Fabry disease models in vitro. Journal of Medical Virology. 71: 173-82. PMID 12938190 DOI: 10.1002/jmv.10467  0.4
2003 Bofill-Mas S, Clemente-Casares P, Major EO, Curfman B, Girones R. Analysis of the excreted JC virus strains and their potential oral transmission. Journal of Neurovirology. 9: 498-507. PMID 12907394 DOI: 10.1080/13550280390218887  0.4
2003 Bachis A, Major EO, Mocchetti I. Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5715-22. PMID 12843275  0.4
2003 Rollison DE, Helzlsouer KJ, Alberg AJ, Hoffman S, Hou J, Daniel R, Shah KV, Major EO. Serum antibodies to JC virus, BK virus, simian virus 40, and the risk of incident adult astrocytic brain tumors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 12: 460-3. PMID 12750243  0.4
2003 Messam CA, Hou J, Gronostajski RM, Major EO. Lineage pathway of human brain progenitor cells identified by JC virus susceptibility. Annals of Neurology. 53: 636-46. PMID 12730998 DOI: 10.1002/ana.10523  0.4
2003 Joseph J, Major EO. Basic, clinical, and epidemiological studies of progressive multifocal leukoencephalopathy: implications for therapy. Journal of Neurovirology. 9: 1-2. PMID 12709863 DOI: 10.1080/13550280390195414  0.4
2003 Seth P, Diaz F, Major EO. Advances in the biology of JC virus and induction of progressive multifocal leukoencephalopathy. Journal of Neurovirology. 9: 236-46. PMID 12707854 DOI: 10.1080/13550280390194019  0.4
2003 Viscidi RP, Rollison DE, Viscidi E, Clayman B, Rubalcaba E, Daniel R, Major EO, Shah KV. Serological cross-reactivities between antibodies to simian virus 40, BK virus, and JC virus assessed by virus-like-particle-based enzyme immunoassays. Clinical and Diagnostic Laboratory Immunology. 10: 278-85. PMID 12626455 DOI: 10.1128/CDLI.10.2.278-285.2003  0.4
2003 Chauhan A, Turchan J, Pocernich C, Bruce-Keller A, Roth S, Butterfield DA, Major EO, Nath A. Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport. The Journal of Biological Chemistry. 278: 13512-9. PMID 12551932 DOI: 10.1074/jbc.M209381200  0.4
2003 Johnson RT, Major EO. Infectious Demyelinating Diseases Myelin Biology and Disorders. 2: 953-983. DOI: 10.1016/B978-012439510-7/50093-0  0.4
2002 Grigolo B, Roseti L, Neri S, Gobbi P, Jensen P, Major EO, Facchini A. Human articular chondrocytes immortalized by HPV-16 E6 and E7 genes: Maintenance of differentiated phenotype under defined culture conditions. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 10: 879-89. PMID 12435333 DOI: 10.1053/joca.2002.0836  0.4
2002 Sabath BF, Major EO. Traffic of JC virus from sites of initial infection to the brain: the path to progressive multifocal leukoencephalopathy. The Journal of Infectious Diseases. 186: S180-6. PMID 12424695 DOI: 10.1086/344280  0.4
2002 Messam CA, Hou J, Berman JW, Major EO. Analysis of the temporal expression of nestin in human fetal brain derived neuronal and glial progenitor cells. Brain Research. Developmental Brain Research. 134: 87-92. PMID 11947939 DOI: 10.1016/S0165-3806(01)00325-X  0.4
2002 Lawrence DM, Major EO. HIV-1 and the brain: connections between HIV-1-associated dementia, neuropathology and neuroimmunology. Microbes and Infection / Institut Pasteur. 4: 301-8. PMID 11909740 DOI: 10.1016/S1286-4579(02)01542-3  0.4
2001 Messam CA, Major EO. Utility of human neural cells and cell lines for anti-viral vaccine research and development. Developments in Biologicals. 106: 299-306; discussion . PMID 11761243  0.4
2001 Hou J, Major EO. Direct and indirect mechanisms of HIV-1 neuropathogenesis in the human central nervous system. Advances in Experimental Medicine and Biology. 493: 29-34. PMID 11727777 DOI: 10.1007/0-306-47611-8_3  0.4
2001 Petrogiannis-Haliotis T, Sakoulas G, Kirby J, Koralnik IJ, Dvorak AM, Monahan-Earley R, DE Girolami PC, DE Girolami U, Upton M, Major EO, Pfister LA, Joseph JT. BK-related polyomavirus vasculopathy in a renal-transplant recipient. The New England Journal of Medicine. 345: 1250-5. PMID 11680445 DOI: 10.1056/NEJMoa010319  0.4
2001 Monaco MC, Sabath BF, Durham LC, Major EO. JC virus multiplication in human hematopoietic progenitor cells requires the NF-1 class D transcription factor. Journal of Virology. 75: 9687-95. PMID 11559801 DOI: 10.1128/JVI.75.20.9687-9695.2001  0.4
2001 Jensen PN, Major EO. A classification scheme for human polyomavirus JCV variants based on the nucleotide sequence of the noncoding regulatory region. Journal of Neurovirology. 7: 280-7. PMID 11517403 DOI: 10.1080/13550280152537102  0.4
2001 Clifford DB, Major EO. The biology of JC virus and progressive multifocal leukoencephalopathy Journal of Neurovirology. 7: 279. PMID 11517402 DOI: 10.1080/13550280152537094  0.4
2001 Sánchez-Pernaute R, Studer L, Bankiewicz KS, Major EO, McKay RD. In vitro generation and transplantation of precursor-derived human dopamine neurons. Journal of Neuroscience Research. 65: 284-8. PMID 11494363 DOI: 10.1002/jnr.1152  0.4
2000 Major EO. From telomeres to T-antigens: many roads...multiple pathways...novel associations in the search for the origins of human gliomas. Annals of Neurology. 48: 823-5. PMID 11117537 DOI: 10.1002/1531-8249(200012)48:6<823::AID-ANA1>3.0.CO;2-0  0.4
2000 Hou J, Major EO. Progressive multifocal leukoencephalopathy: JC virus induced demyelination in the immune compromised host. Journal of Neurovirology. 6: S98-S100. PMID 10871795  0.4
2000 Messam CA, Major EO. Stages of restricted HIV-1 infection in astrocyte cultures derived from human fetal brain tissue. Journal of Neurovirology. 6: S90-4. PMID 10871771  0.4
2000 Wu DT, Woodman SE, Weiss JM, McManus CM, D'Aversa TG, Hesselgesser J, Major EO, Nath A, Berman JW. Mechanisms of leukocyte trafficking into the CNS. Journal of Neurovirology. 6: S82-5. PMID 10871769  0.4
2000 Major EO, Rausch D, Marra C, Clifford D. HIV-associated dementia. Science (New York, N.Y.). 288: 440-2. PMID 10798979  0.4
2000 Messam CA, Hou J, Major EO. Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody. Experimental Neurology. 161: 585-96. PMID 10686078 DOI: 10.1006/exnr.1999.7319  0.4
2000 Power C, Gladden JG, Halliday W, Del Bigio MR, Nath A, Ni W, Major EO, Blanchard J, Mowat M. AIDS- and non-AIDS-related PML association with distinct p53 polymorphism. Neurology. 54: 743-6. PMID 10680816  0.4
2000 Hamilton RS, Gravell M, Major EO. Comparison of antibody titers determined by hemagglutination inhibition and enzyme immunoassay for JC virus and BK virus. Journal of Clinical Microbiology. 38: 105-9. PMID 10618072  0.4
1999 Berger JR, Major EO. Progressive multifocal leukoencephalopathy. Seminars in Neurology. 19: 193-200. PMID 10718540 DOI: 10.1055/s-2008-1040837  0.4
1999 Weiss JM, Nath A, Major EO, Berman JW. HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes. Journal of Immunology (Baltimore, Md. : 1950). 163: 2953-9. PMID 10453044  0.4
1999 Laghi L, Randolph AE, Chauhan DP, Marra G, Major EO, Neel JV, Boland CR. JC virus DNA is present in the mucosa of the human colon and in colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 96: 7484-9. PMID 10377441 DOI: 10.1073/pnas.96.13.7484  0.4
1999 Yiannoutsos CT, Major EO, Curfman B, Jensen PN, Gravell M, Hou J, Clifford DB, Hall CD. Relation of JC virus DNA in the cerebrospinal fluid to survival in acquired immunodeficiency syndrome patients with biopsy-proven progressive multifocal leukoencephalopathy. Annals of Neurology. 45: 816-21. PMID 10360779 DOI: 10.1002/1531-8249(199906)45:6<816::AID-ANA21>3.0.CO;2-W  0.4
1999 Nath A, Conant K, Chen P, Scott C, Major EO. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon. The Journal of Biological Chemistry. 274: 17098-102. PMID 10358063 DOI: 10.1074/jbc.274.24.17098  0.4
1999 Jensen PN, Major EO. Viral variant nucleotide sequences help expose leukocytic positioning in the JC virus pathway to the CNS. Journal of Leukocyte Biology. 65: 428-38. PMID 10204570  0.4
1998 Major EO, Neel JV. The JC and BK human polyoma viruses appear to be recent introductions to some South American Indian tribes: there is no serological evidence of cross-reactivity with the simian polyoma virus SV40. Proceedings of the National Academy of Sciences of the United States of America. 95: 15525-30. PMID 9861002  0.4
1998 Monaco MC, Jensen PN, Hou J, Durham LC, Major EO. Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. Journal of Virology. 72: 9918-23. PMID 9811728  0.4
1998 Monaco MC, Shin J, Major EO. JC virus infection in cells from lymphoid tissue. Developments in Biological Standardization. 94: 115-22. PMID 9776232  0.4
1998 Hou J, Major EO. The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line. Journal of Neurovirology. 4: 451-6. PMID 9718138 DOI: 10.3109/13550289809114545  0.4
1998 Conant K, Ahmed U, Schwartz JP, Major EO. IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism. Journal of Neuroimmunology. 88: 39-44. PMID 9688322 DOI: 10.1016/S0165-5728(98)00069-1  0.4
1998 Conant K, Garzino-Demo A, Nath A, McArthur JC, Halliday W, Power C, Gallo RC, Major EO. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 3117-21. PMID 9501225 DOI: 10.1073/pnas.95.6.3117  0.4
1997 Weber T, Major EO. Progressive multifocal leukoencephalopathy: molecular biology, pathogenesis and clinical impact. Intervirology. 40: 98-111. PMID 9450227  0.4
1997 Gallia GL, Houff SA, Major EO, Khalili K. Review: JC virus infection of lymphocytes--revisited. The Journal of Infectious Diseases. 176: 1603-9. PMID 9395374  0.4
1997 Heyes MP, Chen CY, Major EO, Saito K. Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types. The Biochemical Journal. 326: 351-6. PMID 9291104  0.4
1997 Shinohara T, Nagashima K, Major EO. Propagation of the human polyomavirus, JCV, in human neuroblastoma cell lines. Virology. 228: 269-77. PMID 9123834 DOI: 10.1006/viro.1996.8409  0.4
1997 Major EO, Monaco MC, Shinohara T, Curfman BL, Jensen P. The pathogenesis of JC virus induced progressive multifocal leukoencephalopathy involves infection of the immune system Journal of Neurovirology. 3: S16.  0.4
1996 Lazutka JR, Neel JV, Major EO, Dedonyte V, Mierauskine J, Slapsyte G, Kesminiene A. High titers of antibodies to two human polyomaviruses, JCV and BKV, correlate with increased frequency of chromosomal damage in human lymphocytes. Cancer Letters. 109: 177-83. PMID 9020918 DOI: 10.1016/S0304-3835(96)04448-5  0.4
1996 Dayton ET, Major EO. Recombinant human interleukin 1 beta induces production of prostaglandins in primary human fetal astrocytes and immortalized human fetal astrocyte cultures. Journal of Neuroimmunology. 71: 11-8. PMID 8982097 DOI: 10.1016/S0165-5728(96)00111-7  0.4
1996 Heyes MP, Achim CL, Wiley CA, Major EO, Saito K, Markey SP. Human microglia convert l-tryptophan into the neurotoxin quinolinic acid. The Biochemical Journal. 320: 595-7. PMID 8973572  0.4
1996 Sumner C, Shinohara T, Durham L, Traub R, Major EO, Amemiya K. Expression of multiple classes of the nuclear factor-1 family in the developing human brain: differential expression of two classes of NF-1 genes. Journal of Neurovirology. 2: 87-100. PMID 8799200  0.4
1996 Monaco MC, Atwood WJ, Gravell M, Tornatore CS, Major EO. JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency. Journal of Virology. 70: 7004-12. PMID 8794345  0.4
1996 Conant K, Ma M, Nath A, Major EO. Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes. Journal of Virology. 70: 1384-9. PMID 8627654  0.4
1996 Kennedy PGE, Major EO. Oligodendroglial development in fetal cerebrum [4] Annals of Neurology. 39: 684-685. PMID 8619560  0.4
1996 Neel JV, Major EO, Awa AA, Glover T, Burgess A, Traub R, Curfman B, Satoh C. Hypothesis: "Rogue cell"-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 2690-5. PMID 8610102  0.4
1995 Atwood WJ, Wang L, Durham LC, Amemiya K, Traub RG, Major EO. Evaluation of the role of cytokine activation in the multiplication of JC virus (JCV) in human fetal glial cells. Journal of Neurovirology. 1: 40-9. PMID 9222341  0.4
1995 Major EO, Ault GS. Progressive multifocal leukoencephalopathy: clinical and laboratory observations on a viral induced demyelinating disease in the immunodeficient patient. Current Opinion in Neurology. 8: 184-90. PMID 7551117  0.4
1994 Amemiya K, Durham L, Major EO. Overexpression and reactivation of binding activity of the recombinant CTF/NF-1 transcription factor. Protein Expression and Purification. 5: 57-64. PMID 8167474 DOI: 10.1006/prep.1994.1008  0.4
1994 Katz DA, Berger JR, Hamilton B, Major EO, Post MJ. Progressive multifocal leukoencephalopathy complicating Wiskott-Aldrich syndrome. Report of a case and review of the literature of progressive multifocal leukoencephalopathy with other inherited immunodeficiency states. Archives of Neurology. 51: 422-6. PMID 8155020  0.4
1994 Tornatore C, Chandra R, Berger JR, Major EO. HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology. 44: 481-7. PMID 8145919  0.4
1994 Conant K, Atwood WJ, Traub R, Tornatore C, Major EO. An increase in p50/p65 NF-kB binding to the HIV-1 LTR is not sufficient to increase viral expression in the primary human astrocyte. Virology. 205: 586-90. PMID 7975262 DOI: 10.1006/viro.1994.1685  0.4
1994 Kennedy PG, Major EO, Williams RK, Straus SE. Down-regulation of glial fibrillary acidic protein expression during acute lytic varicella-zoster virus infection of cultured human astrocytes. Virology. 205: 558-62. PMID 7975257 DOI: 10.1006/viro.1994.1679  0.4
1994 Conant K, Tornatore C, Atwood W, Meyers K, Traub R, Major EO. In vivo and in vitro infection of the astrocyte by HIV-1. Advances in Neuroimmunology. 4: 287-9. PMID 7874397 DOI: 10.1016/S0960-5428(06)80269-X  0.4
1994 Atwood WJ, Tornatore CS, Traub R, Conant K, Drew PD, Major EO. Stimulation of HIV type 1 gene expression and induction of NF-kappa B (p50/p65)-binding activity in tumor necrosis factor alpha-treated human fetal glial cells. Aids Research and Human Retroviruses. 10: 1207-11. PMID 7848678  0.4
1994 Tornatore C, Amemiya K, Atwood W, Conant K, Major EO, Berger J. JC virus: Current concepts and controversies in the molecular virology and pathogenesis of progressive multifocal leucoencephalopathy Reviews in Medical Virology. 4: 197-219. DOI: 10.1002/rmv.1980040306  0.4
1993 Heyes MP, Saito K, Major EO, Milstien S, Markey SP, Vickers JH. A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate. Brain : a Journal of Neurology. 116: 1425-50. PMID 8293279  0.4
1993 Atwood WJ, Berger JR, Kaderman R, Tornatore CS, Major EO. Human immunodeficiency virus type 1 infection of the brain. Clinical Microbiology Reviews. 6: 339-66. PMID 8269391  0.4
1993 Atwood WJ, Tornatore CS, Meyers K, Major EO. HIV-1 mRNA transcripts from persistently infected human fetal astrocytes. Annals of the New York Academy of Sciences. 693: 324-5. PMID 8267293 DOI: 10.1111/j.1749-6632.1993.tb26298.x  0.4
1992 Kenten JH, Gudibande S, Link J, Willey JJ, Curfman B, Major EO, Massey RJ. Improved electrochemiluminescent label for DNA probe assays: rapid quantitative assays of HIV-1 polymerase chain reaction products. Clinical Chemistry. 38: 873-9. PMID 1597013  0.4
1992 Berger JR, Scott G, Albrecht J, Belman AL, Tornatore C, Major EO. Progressive multifocal leukoencephalopathy in HIV-1-infected children. Aids (London, England). 6: 837-41. PMID 1418781  0.4
1992 Buckle GJ, Godec MS, Rubi JU, Tornatore C, Major EO, Gibbs CJ, Gajdusek DC, Asher DM. Lack of JC viral genomic sequences in multiple sclerosis brain tissue by polymerase chain reaction. Annals of Neurology. 32: 829-31. PMID 1335225 DOI: 10.1002/ana.410320622  0.4
1992 Atwood WJ, Amemiya K, Traub R, Harms J, Major EO. Interaction of the human polyomavirus, JCV, with human B-lymphocytes. Virology. 190: 716-23. PMID 1325703 DOI: 10.1016/0042-6822(92)90909-9  0.4
1992 Amemiya K, Traub R, Durham L, Major EO. Adjacent nuclear factor-1 and activator protein binding sites in the enhancer of the neurotropic JC virus. A common characteristic of many brain-specific genes. The Journal of Biological Chemistry. 267: 14204-11. PMID 1321139  0.4
1992 Tornatore C, Berger JR, Houff SA, Curfman B, Meyers K, Winfield D, Major EO. Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Annals of Neurology. 31: 454-62. PMID 1316734 DOI: 10.1002/ana.410310426  0.4
1992 Berger JR, Tornatore C, Major EO, Bruce J, Shapshak P, Yoshioka M, Houff S, Sheremata W, Horton GF, Landy H. Relapsing and remitting human immunodeficiency virus-associated leukoencephalomyelopathy. Annals of Neurology. 31: 34-8. PMID 1311910 DOI: 10.1002/ana.410310107  0.4
1992 Major EO, Amemiya K, Tornatore CS, Houff SA, Berger JR. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clinical Microbiology Reviews. 5: 49-73. PMID 1310438  0.4
1991 Tornatore C, Nath A, Amemiya K, Major EO. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. Journal of Virology. 65: 6094-100. PMID 1920627  0.4
1991 Assouline JG, Major EO. Human fetal Schwann cells support JC virus multiplication. Journal of Virology. 65: 1002-6. PMID 1846179  0.4
1991 Vitković L, Wood GP, Major EO, Fauci AS. Human astrocytes stimulate HIV-1 expression in a chronically infected promonocyte clone via interleukin-6. Aids Research and Human Retroviruses. 7: 723-7. PMID 1742078  0.4
1990 Dyson N, Bernards R, Friend SH, Gooding LR, Hassell JA, Major EO, Pipas JM, Vandyke T, Harlow E. Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. Journal of Virology. 64: 1353-6. PMID 2154613  0.4
1990 Major EO, Amemiya K, Elder G, Houff SA. Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV. Journal of Neuroscience Research. 27: 461-71. PMID 1964178 DOI: 10.1002/jnr.490270405  0.4
1989 Houff SA, Katz D, Kufta CV, Major EO. A rapid method for in situ hybridization for viral DNA in brain biopsies from patients with AIDS. Aids (London, England). 3: 843-5. PMID 2561055  0.4
1989 Major EO, Vacante DA. Human fetal astrocytes in culture support the growth of the neurotropic human polyomavirus, JCV. Journal of Neuropathology and Experimental Neurology. 48: 425-36. PMID 2543798  0.4
1989 Vacante DA, Traub R, Major EO. Extension of JC virus host range to monkey cells by insertion of a simian virus 40 enhancer into the JC virus regulatory region. Virology. 170: 353-61. PMID 2543122  0.4
1989 Amemiya K, Traub R, Durham L, Major EO. Interaction of a nuclear factor-1-like protein with the regulatory region of the human polyomavirus JC virus. The Journal of Biological Chemistry. 264: 7025-32. PMID 2540170  0.4
1988 Elder GA, Major EO. Early appearance of type II astrocytes in developing human fetal brain. Brain Research. 470: 146-50. PMID 3409045 DOI: 10.1016/0165-3806(88)90211-8  0.4
1988 Amirhaeri S, Wohlrab F, Major EO, Wells RD. Unusual DNA structure in the regulatory region of the human papovavirus JC virus. Journal of Virology. 62: 922-31. PMID 2828687  0.4
1988 Houff SA, Major EO, Katz DA, Kufta CV, Sever JL, Pittaluga S, Roberts JR, Gitt J, Saini N, Lux W. Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. The New England Journal of Medicine. 318: 301-5. PMID 2827029 DOI: 10.1056/NEJM198802043180507  0.4
1987 Aksamit AJ, Major EO, Ghatak NR, Sidhu GS, Parisi JE, Guccion JG. Diagnosis of progressive multifocal leukoencephalopathy by brain biopsy with biotin labeled DNA:DNA in situ hybridization. Journal of Neuropathology and Experimental Neurology. 46: 556-66. PMID 3040916  0.4
1987 Major EO, Vacante DA, Traub RG, London WT, Sever JL. Owl monkey astrocytoma cells in culture spontaneously produce infectious JC virus which demonstrates altered biological properties. Journal of Virology. 61: 1435-41. PMID 3033272  0.4
1986 Aksamit AJ, Sever JL, Major EO. Progressive multifocal leukoencephalopathy: JC virus detection by in situ hybridization compared with immunohistochemistry. Neurology. 36: 499-504. PMID 3008027  0.4
1986 Major EO, Traub RG. JC virus T protein during productive infection in human fetal brain and kidney cells. Virology. 148: 221-5. PMID 3002030 DOI: 10.1016/0042-6822(86)90418-6  0.4
1985 Aksamit AJ, Mourrain P, Sever JL, Major EO. Progressive multifocal leukoencephalopathy: investigation of three cases using in situ hybridization with JC virus biotinylated DNA probe. Annals of Neurology. 18: 490-6. PMID 3000279 DOI: 10.1002/ana.410180412  0.4
1985 Major EO, Miller AE, Mourrain P, Traub RG, de Widt E, Sever J. Establishment of a line of human fetal glial cells that supports JC virus multiplication. Proceedings of the National Academy of Sciences of the United States of America. 82: 1257-61. PMID 2983332 DOI: 10.1073/pnas.82.4.1257  0.4
1984 Major EO, Matsumura P. Human embryonic kidney cells: stable transformation with an origin-defective simian virus 40 DNA and use as hosts for human papovavirus replication. Molecular and Cellular Biology. 4: 379-82. PMID 6321962  0.4
1984 Major EO, Mourrain P, Cummins C. JC virus-induced owl monkey glioblastoma cells in culture: biological properties associated with the viral early gene product. Virology. 136: 359-67. PMID 6087549 DOI: 10.1016/0042-6822(84)90172-7  0.4
1983 Miller NR, Major EO, Wallen WC. Transfection of human fetal glial cells with molecularly cloned JCV DNA. Progress in Clinical and Biological Research. 105: 29-40. PMID 6304766  0.4
1983 Major EO. JC virus T protein expression in owl monkey tumor cell lines. Progress in Clinical and Biological Research. 105: 289-98. PMID 6304765  0.4
1983 Major EO. Human papovavirus infection of an SV40-transformed human embryonic kidney cell line. Progress in Clinical and Biological Research. 105: 15-27. PMID 6304752  0.4
1981 Rundell K, Major EO, Lampert M. Association of cellular 56,000- and 32,000-molecular-weight protein with BK virus and polyoma virus t-antigens. Journal of Virology. 37: 1090-3. PMID 6262529  0.4
1980 Major EO, Ehlke S, Lampert M. Selection of somatic cell hybrids between BK virus transformed BHK-21 and human embryonic kidney cells to study viral gene expression. Journal of Virological Methods. 1: 139-47. PMID 6268646 DOI: 10.1016/0166-0934(80)90010-5  0.4
1979 Bourne KA, Major EO, Khoobyarian N. Inhibition of murine sarcoma virus induced transformation in an adenovirus -- NRK system. In Vitro. 15: 664-8. PMID 231569 DOI: 10.1007/BF02618244  0.4
1978 Bourne KA, Major EO, Khoobyarian N. A variant of adenovirus 12 producing cytoplasmic accumulation of capsid proteins. The Journal of General Virology. 40: 685-9. PMID 690616  0.4
1977 Molinaro GA, Major EO, Bernhardt G, Dray S, di Mayorca G. Similar cell surface antigens on hamster cells transformed by different papovaviruses. Journal of Immunology (Baltimore, Md. : 1950). 118: 2295-8. PMID 68085  0.4
1976 Wright PJ, Bernhardt G, Major EO, di Mayorca G. Comparison of the serology, transforming ability, and polypeptide composition of human papovaviruses isolated from urine. Journal of Virology. 17: 762-75. PMID 56460  0.4
1973 Major EO, Di Mayorca G. Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus. Proceedings of the National Academy of Sciences of the United States of America. 70: 3210-2. PMID 4361683  0.4
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