Jakob Begun, Ph.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Begun J, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.614
2020 Aysha AA, Rentsch C, Prentice R, Johnson D, Bryant RV, Ward MG, Costello SP, Lewindon P, Ghaly S, Connor SJ, Begun J, Christensen B. Practical management of inflammatory bowel disease patients during the COVID-19 pandemic: expert commentary from the Gastroenterological Society of Australia Inflammatory Bowel Disease faculty. Internal Medicine Journal. 50: 798-804. PMID 32656985 DOI: 10.1111/Imj.14889  0.324
2020 Pulley J, Todd A, Flatley C, Begun J. Malnutrition and quality of life among adult inflammatory bowel disease patients. Jgh Open : An Open Access Journal of Gastroenterology and Hepatology. 4: 454-460. PMID 32514453 DOI: 10.1002/Jgh3.12278  0.306
2020 Rajagopalan A, Sathananthan D, An YK, Van De Ven L, Martin S, Fon J, Costello SP, Begun J, Bryant RV. Gastrointestinal ultrasound in inflammatory bowel disease care: Patient perceptions and impact on disease-related knowledge. Jgh Open : An Open Access Journal of Gastroenterology and Hepatology. 4: 267-272. PMID 32280776 DOI: 10.1002/Jgh3.12268  0.321
2020 Giri R, Shamsunnahar K, Salim A, Capon R, Morrison M, O Cuiv P, Begun J. OP36 Investigating the role of bioactives produced by gut bacteria to modulate immune response in inflammatory bowel disease Journal of Crohn's and Colitis. 14: S037-S038. DOI: 10.1093/Ecco-Jcc/Jjz203.035  0.381
2020 Reed H, Begun J. The future of faecal microbiota transplantation in gastrointestinal illness Microbiology Australia. 41: 70-74. DOI: 10.1071/Ma20027  0.354
2020 Giri R, Hoedt EC, Khushi S, Salim A, Capon R, Morrison M, Cuiv PO, Begun J. Tu1302 INVESTIGATING THE ROLE OF BIOACTIVES PRODUCED BY GUT BACTERIA TO MODULATE IMMUNE RESPONSE IN IBD Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33310-2  0.336
2019 An YK, Prince D, Gardiner F, Neeman T, Linedale EC, Andrews JM, Connor S, Begun J. Faecal calprotectin testing for identifying patients with organic gastrointestinal disease: systematic review and meta-analysis. The Medical Journal of Australia. PMID 31680263 DOI: 10.5694/Mja2.50384  0.316
2019 Khor B, Conway KL, Omar AS, Biton M, Haber AL, Rogel N, Baxt LA, Begun J, Kuballa P, Gagnon JD, Lassen KG, Regev A, Xavier RJ. Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1. Journal of Immunology (Baltimore, Md. : 1950). PMID 31451676 DOI: 10.4049/Jimmunol.1800419  0.345
2019 Giri R, Cuiv PO, Begun J. Mo1930 – Harnessing Anti-Inflammatory Gut Bioactives to Modulate the Immune Response in Ibd Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39197-8  0.311
2018 Begun J. Predictors in inflammatory bowel disease: Looking into the magic ball: Session one summary. Journal of Gastroenterology and Hepatology. 33: 4. PMID 30187557 DOI: 10.1111/Jgh.14415  0.317
2018 Begun J. Selectively targeting the gut in inflammatory bowel disease: Session four summary. Journal of Gastroenterology and Hepatology. 33: 25. PMID 30187550 DOI: 10.1111/Jgh.14430  0.319
2018 Ó Cuív P, Giri R, Hoedt EC, McGuckin MA, Begun J, Morrison M. AHG0090 is a Genetically Tractable Bacterium and Produces a Secreted Peptidic Bioactive that Suppresses Nuclear Factor Kappa B Activation in Human Gut Epithelial Cells. Frontiers in Immunology. 9: 790. PMID 29720977 DOI: 10.3389/Fimmu.2018.00790  0.307
2018 Bryant RV, Friedman A, Wright EK, Taylor K, Begun J, Maconi G, Maaser C, Novak KL, Kucharzik T, Atkinson NSS, Asthana A, Gibson PR. Gastrointestinal ultrasound in inflammatory bowel disease: an underused resource with potential paradigm-changing application. Gut. PMID 29437914 DOI: 10.1136/Gutjnl-2017-315655  0.323
2018 Giri R, Cuiv PO, Begun J. Tu1852 - Role of Anti-Inflammatory Gut Bioactives in the Modulation of Immune Response in Crohn's Disease Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)33478-4  0.348
2018 Krishnaprasad K, Walsh A, Begun J, Bell S, Carter D, Grafton R, Sechi A, Sewell K, McMahon A, Connor SJ, Radford-Smith GL, Andrews JM. Tu1020 - Crohn's Colitis Care (CCcare) - Development and Testing of a Bespoke Cloud-Based Clinical Management System for Inflammatory Bowel Disease (IBD) Gastroenterology. 154: S-892. DOI: 10.1016/S0016-5085(18)33012-9  0.305
2018 Luong D, Begun J. Sa1828 - Enteropathogens Detected on Stool Culture and Multiplex PCR are a Common Finding in Inflammatory Bowel Disease Patients Gastroenterology. 154: S-410-S-411. DOI: 10.1016/S0016-5085(18)31651-2  0.301
2017 Mitrev N, Vande Casteele N, Seow CH, Andrews JM, Connor SJ, Moore GT, Barclay M, Begun J, Bryant R, Chan W, Corte C, Ghaly S, Lemberg DA, Kariyawasam V, Lewindon P, et al. Review article: consensus statements on therapeutic drug monitoring of anti-tumour necrosis factor therapy in inflammatory bowel diseases. Alimentary Pharmacology & Therapeutics. PMID 29027257 DOI: 10.1111/Apt.14368  0.308
2017 Florin T, Movva R, Begun J, Duley J, Oancea I, O Cuiv P. Colonic thioguanine pro-drug: investigation of microbiome and novel host metabolism. Gut Microbes. 0. PMID 28976243 DOI: 10.1080/19490976.2017.1387343  0.322
2017 Ó Cuív P, de Wouters T, Giri R, Mondot S, Smith WJ, Blottière HM, Begun J, Morrison M. The gut bacterium and pathobiont Bacteroides vulgatus activates NF-κB in a human gut epithelial cell line in a strain and growth phase dependent manner. Anaerobe. PMID 28583864 DOI: 10.1016/J.Anaerobe.2017.06.002  0.301
2016 Elshaer D, Begun J. The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis. Seminars in Cell & Developmental Biology. PMID 27565684 DOI: 10.1016/J.Semcdb.2016.08.018  0.393
2016 Oancea I, Movva R, Das I, Aguirre de Cárcer D, Schreiber V, Yang Y, Purdon A, Harrington B, Proctor M, Wang R, Sheng Y, Lobb M, Lourie R, Ó Cuív P, Duley JA, ... Begun J, et al. Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism. Gut. PMID 27411368 DOI: 10.1136/Gutjnl-2015-310874  0.317
2016 Lassen KG, McKenzie CI, Mari M, Murano T, Begun J, Baxt LA, Goel G, Villablanca EJ, Kuo SY, Huang H, Macia L, Bhan AK, Batten M, Daly MJ, Reggiori F, et al. Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk. Immunity. PMID 27287411 DOI: 10.1016/J.Immuni.2016.05.007  0.358
2016 Ó Cuív P, Begun J, Keely S, Lewindon PJ, Morrison M. Towards an integrated understanding of the therapeutic utility of exclusive enteral nutrition in the treatment of Crohn's disease. Food & Function. PMID 26948398 DOI: 10.1039/C5Fo01196E  0.314
2015 Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, et al. Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy. Cell Reports. 11: 1905-18. PMID 26095365 DOI: 10.1016/J.Celrep.2015.05.045  0.351
2012 Huett A, Heath RJ, Begun J, Sassi SO, Baxt LA, Vyas JM, Goldberg MB, Xavier RJ. The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium. Cell Host & Microbe. 12: 778-90. PMID 23245322 DOI: 10.1016/J.Chom.2012.10.019  0.357
2008 Miyata S, Begun J, Troemel ER, Ausubel FM. DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans. Genetics. 178: 903-18. PMID 18245330 DOI: 10.1534/Genetics.107.083923  0.555
2007 Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM, Sifri CD. Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. Plos Pathogens. 3: e57. PMID 17447841 DOI: 10.1371/Journal.Ppat.0030057  0.575
2005 Sifri CD, Begun J, Ausubel FM. The worm has turned--microbial virulence modeled in Caenorhabditis elegans. Trends in Microbiology. 13: 119-27. PMID 15737730 DOI: 10.1016/J.Tim.2005.01.003  0.556
2005 Begun J, Sifri CD, Goldman S, Calderwood SB, Ausubel FM. Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model. Infection and Immunity. 73: 872-7. PMID 15664928 DOI: 10.1128/Iai.73.2.872-877.2005  0.517
2004 Bolm M, Chhatwal GS, Jansen WTM, Ausubel FM, Begun J, Kim DH, Moy T, Ruvkun G, Calderwood SB, Sifri CD, Garsin DA. Bacterial Resistance of daf-2 Mutants [2] (multiple letters) Science. 303: 1976. PMID 15044786  0.6
2003 Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science (New York, N.Y.). 300: 1921. PMID 12817143 DOI: 10.1126/Science.1080147  0.691
2003 Sifri CD, Begun J, Ausubel FM, Calderwood SB. Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infection and Immunity. 71: 2208-17. PMID 12654843 DOI: 10.1128/Iai.71.4.2208-2217.2003  0.564
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