Adam G. Walker, Ph.D. - Publications

Drug Discovery Vanderbilt University, Nashville, TN 

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Senter RK, Ghoshal A, Walker AG, Xiang Z, Niswender CM, Conn PJ. The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies. Current Neuropharmacology. 14: 455-73. PMID 27296640  1
2015 Klar R, Walker AG, Ghose D, Grueter BA, Engers DW, Hopkins CR, Lindsley CW, Xiang Z, Conn PJ, Niswender CM. Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7600-15. PMID 25972184 DOI: 10.1523/JNEUROSCI.4543-14.2015  1
2015 Walker AG, Wenthur CJ, Xiang Z, Rook JM, Emmitte KA, Niswender CM, Lindsley CW, Conn PJ. Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction. Proceedings of the National Academy of Sciences of the United States of America. 112: 1196-201. PMID 25583490 DOI: 10.1073/pnas.1416196112  1
2015 Walker AG, Conn PJ. Group I and group II metabotropic glutamate receptor allosteric modulators as novel potential antipsychotics. Current Opinion in Pharmacology. 20: 40-5. PMID 25462291 DOI: 10.1016/j.coph.2014.11.003  1
2014 Jalan-Sakrikar N, Field JR, Klar R, Mattmann ME, Gregory KJ, Zamorano R, Engers DW, Bollinger SR, Weaver CD, Days EL, Lewis LM, Utley TJ, Hurtado M, Rigault D, Acher F, ... Walker AG, et al. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. Acs Chemical Neuroscience. 5: 1221-37. PMID 25225882 DOI: 10.1021/cn500153z  1
2012 Digby GJ, Noetzel MJ, Bubser M, Utley TJ, Walker AG, Byun NE, Lebois EP, Xiang Z, Sheffler DJ, Cho HP, Davis AA, Nemirovsky NE, Mennenga SE, Camp BW, Bimonte-Nelson HA, et al. Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8532-44. PMID 22723693 DOI: 10.1523/JNEUROSCI.0337-12.2012  1
2011 Field JR, Walker AG, Conn PJ. Targeting glutamate synapses in schizophrenia. Trends in Molecular Medicine. 17: 689-98. PMID 21955406 DOI: 10.1016/j.molmed.2011.08.004  1
2011 Miller BR, Walker AG, Barton SJ, Rebec GV. Dysregulated Neuronal Activity Patterns Implicate Corticostriatal Circuit Dysfunction in Multiple Rodent Models of Huntington's Disease. Frontiers in Systems Neuroscience. 5: 26. PMID 21629717 DOI: 10.3389/fnsys.2011.00026  1
2011 Walker AG, Ummel JR, Rebec GV. Reduced expression of conditioned fear in the R6/2 mouse model of Huntington's disease is related to abnormal activity in prelimbic cortex. Neurobiology of Disease. 43: 379-87. PMID 21515374 DOI: 10.1016/j.nbd.2011.04.009  1
2011 Wilber AA, Walker AG, Southwood CJ, Farrell MR, Lin GL, Rebec GV, Wellman CL. Chronic stress alters neural activity in medial prefrontal cortex during retrieval of extinction. Neuroscience. 174: 115-31. PMID 21044660 DOI: 10.1016/j.neuroscience.2010.10.070  1
2010 Miller BR, Walker AG, Fowler SC, von Hörsten S, Riess O, Johnson MA, Rebec GV. Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington's disease. Neurobiology of Disease. 37: 106-13. PMID 19818852 DOI: 10.1016/j.nbd.2009.09.013  1
2008 Walker AG, Miller BR, Fritsch JN, Barton SJ, Rebec GV. Altered information processing in the prefrontal cortex of Huntington's disease mouse models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8973-82. PMID 18768691 DOI: 10.1523/JNEUROSCI.2804-08.2008  1
2008 Miller BR, Walker AG, Shah AS, Barton SJ, Rebec GV. Dysregulated information processing by medium spiny neurons in striatum of freely behaving mouse models of Huntington's disease. Journal of Neurophysiology. 100: 2205-16. PMID 18667541 DOI: 10.1152/jn.90606.2008  1
2008 Walker AG, Steinmetz JE. Hippocampal lesions in rats differentially affect long- and short-trace eyeblink conditioning. Physiology & Behavior. 93: 570-8. PMID 18061635 DOI: 10.1016/j.physbeh.2007.10.018  1
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