| Year |
Citation |
Score |
| 2023 |
Kriwacki R, Gibbs E, Miao Q, Ferrolino M, Bajpai R, Hassan A, Phillips A, Pitre A, Kümmerle R, Pruett-Miller S, Heller W, Stanley C, Perrone B. p14ARF forms meso-scale assemblies upon phase separation with NPM1. Research Square. PMID 38106181 DOI: 10.21203/rs.3.rs-3592059/v1 |
0.771 |
|
| 2022 |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y, Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M. Chromatin localization of nucleophosmin organizes ribosome biogenesis. Molecular Cell. PMID 36423630 DOI: 10.1016/j.molcel.2022.10.033 |
0.764 |
|
| 2021 |
Chandra B, Michmerhuizen NL, Shirnekhi HK, Tripathi S, Pioso BJ, Baggett DW, Mitrea DM, Iacobucci I, White MR, Chen J, Park CG, Wu H, Pounds S, Medyukhina A, Khairy K, ... ... Kriwacki RW, et al. Phase Separation mediates NUP98 Fusion Oncoprotein Leukemic Transformation. Cancer Discovery. PMID 34903620 DOI: 10.1158/2159-8290.CD-21-0674 |
0.764 |
|
| 2020 |
Riback JA, Zhu L, Ferrolino MC, Tolbert M, Mitrea DM, Sanders DW, Wei MT, Kriwacki RW, Brangwynne CP. Composition-dependent thermodynamics of intracellular phase separation. Nature. 581: 209-214. PMID 32405004 DOI: 10.1038/S41586-020-2256-2 |
0.768 |
|
| 2020 |
Gibbs EB, Perrone B, Hassan A, Kümmerle R, Kriwacki R. NPM1 Exhibits Structural and Dynamic Heterogeneity Upon Phase Separation with the Tumor Suppressor ARF Biophysical Journal. 118: 539a. DOI: 10.1016/J.Bpj.2019.11.2953 |
0.31 |
|
| 2019 |
Gibbs E, Perrone B, Hassan A, Kümmerle R, Kriwacki R. NPM1 exhibits structural and dynamic heterogeneity upon phase separation with the p14ARF tumor suppressor. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 310: 106646. PMID 31751897 DOI: 10.1016/J.Jmr.2019.106646 |
0.425 |
|
| 2019 |
Phillips AH, Kriwacki RW. Intrinsic protein disorder and protein modifications in the processing of biological signals. Current Opinion in Structural Biology. 60: 1-6. PMID 31629249 DOI: 10.1016/J.Sbi.2019.09.003 |
0.374 |
|
| 2019 |
White MR, Mitrea DM, Zhang P, Stanley CB, Cassidy DE, Nourse A, Phillips AH, Tolbert M, Taylor JP, Kriwacki RW. C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function. Molecular Cell. PMID 30981631 DOI: 10.1016/J.Molcel.2019.03.019 |
0.414 |
|
| 2019 |
Tsytlonok M, Sanabria H, Wang Y, Felekyan S, Hemmen K, Phillips AH, Yun MK, Waddell MB, Park CG, Vaithiyalingam S, Iconaru L, White SW, Tompa P, Seidel CAM, Kriwacki R. Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. Nature Communications. 10: 1676. PMID 30976006 DOI: 10.1038/S41467-019-09446-W |
0.357 |
|
| 2019 |
Beveridge R, Migas LG, Das RK, Pappu RV, Kriwacki RW, Barran PE. Ion mobility mass spectrometry uncovers the impact of the patterning of oppositely charged residues on the conformational distributions of intrinsically disordered proteins. Journal of the American Chemical Society. PMID 30823702 DOI: 10.1021/Jacs.8B13483 |
0.303 |
|
| 2019 |
Kriwacki R, Mitrea D, Ferrolino M, Gibbs E, Phillips AH, Tolbert M, Stanley CB, Nourse A, Onuchic PL, Banerjee PR, Deniz AA. The Ins and Outs of Phase Separation in Nucleolar Biology Biophysical Journal. 116: 454a. DOI: 10.1016/J.Bpj.2018.11.2448 |
0.741 |
|
| 2019 |
Choi J, Mitrea DM, Stanley CB, Ruff KM, Holehouse AS, Kriwacki RW, Pappu RV. Internal Structure of Network Fluid Condensates Formed by Liquid-Liquid Phase Separation of a Multivalent Oligomeric Protein and a Disordered Linear Peptide Biophysical Journal. 116: 349a. DOI: 10.1016/J.Bpj.2018.11.1899 |
0.353 |
|
| 2019 |
Tolbert M, Parish PC, Olson SW, Mitrea DM, Weeks K, Kriwacki RW. Molecular Insights into the Role of RNA Structure in the Phase Separated Nucleolus Biophysical Journal. 116: 348a. DOI: 10.1016/J.Bpj.2018.11.1898 |
0.322 |
|
| 2018 |
Beveridge R, Migas LG, Kriwacki RW, Barran PE. Ion Mobility Mass Spectrometry Measures the Conformational Landscape of p27 and its Domains and how this is Modulated upon Interaction with Cdk2/cyclin A. Angewandte Chemie (International Ed. in English). PMID 30570821 DOI: 10.1002/Anie.201812697 |
0.411 |
|
| 2018 |
Ferrolino MC, Mitrea DM, Michael JR, Kriwacki RW. Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms. Nature Communications. 9: 5064. PMID 30498217 DOI: 10.1038/S41467-018-07530-1 |
0.779 |
|
| 2018 |
Gibbs EB, Kriwacki RW. Linker histones as liquid-like glue for chromatin. Proceedings of the National Academy of Sciences of the United States of America. PMID 30389709 DOI: 10.1073/Pnas.1816936115 |
0.334 |
|
| 2018 |
Mitrea DM, Chandra B, Ferrolino MC, Gibbs EB, Tolbert M, White MR, Kriwacki RW. Methods for Physical Characterization of Phase Separated Bodies and Membrane-Less Organelles. Journal of Molecular Biology. PMID 30017918 DOI: 10.1016/J.Jmb.2018.07.006 |
0.737 |
|
| 2018 |
Chen J, Kriwacki RW. Intrinsically Disordered Proteins: Structure, Function and Therapeutics. Journal of Molecular Biology. PMID 29906412 DOI: 10.1016/J.Jmb.2018.06.012 |
0.337 |
|
| 2018 |
Mitrea DM, Kriwacki RW. On the relationship status for Arf and NPM1 - it's complicated. The Febs Journal. 285: 828-831. PMID 29527821 DOI: 10.1111/Febs.14407 |
0.319 |
|
| 2018 |
Follis AV, Llambi F, Kalkavan H, Yao Y, Phillips AH, Park CG, Marassi FM, Green DR, Kriwacki RW. Regulation of apoptosis by an intrinsically disordered region of Bcl-xL. Nature Chemical Biology. PMID 29507390 DOI: 10.1038/S41589-018-0011-X |
0.406 |
|
| 2018 |
Mitrea DM, Cika JA, Stanley CB, Nourse A, Onuchic PL, Banerjee PR, Phillips AH, Park CG, Deniz AA, Kriwacki RW. Self-interaction of NPM1 modulates multiple mechanisms of liquid-liquid phase separation. Nature Communications. 9: 842. PMID 29483575 DOI: 10.1038/S41467-018-03255-3 |
0.404 |
|
| 2018 |
Phillips AH, Li O, Gay A, Besson A, Kriwacki RW. Mapping interactions between p27 and RhoA that stimulate cell migration. Journal of Molecular Biology. PMID 29410088 DOI: 10.1016/J.Jmb.2018.01.017 |
0.356 |
|
| 2017 |
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, et al. An unexpected protein interaction promotes drug resistance in leukemia. Nature Communications. 8: 1547. PMID 29146910 DOI: 10.1038/S41467-017-01678-Y |
0.349 |
|
| 2017 |
Ragavan M, Iconaru LI, Park CG, Kriwacki RW, Hilty C. Real-Time Analysis of Folding upon Binding of a Disordered Protein by using Dissolution DNP NMR Spectroscopy. Angewandte Chemie (International Ed. in English). PMID 28508552 DOI: 10.1002/Anie.201700464 |
0.376 |
|
| 2017 |
Kriwacki R, Mitrea DM, Follis A, Iconaru L, Cika J, Ban D, Philllips A. Two Decades of IDPs; What have we Learned? Biophysical Journal. 112: 12a-13a. DOI: 10.1016/J.Bpj.2016.11.099 |
0.379 |
|
| 2016 |
Lee KH, Zhang P, Kim HJ, Mitrea DM, Sarkar M, Freibaum BD, Cika J, Coughlin M, Messing J, Molliex A, Maxwell BA, Kim NC, Temirov J, Moore J, Kolaitis RM, ... ... Kriwacki RW, et al. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell. 167: 774-788.e17. PMID 27768896 DOI: 10.1016/J.Cell.2016.10.002 |
0.421 |
|
| 2016 |
Feric M, Vaidya N, Harmon TS, Mitrea DM, Zhu L, Richardson TM, Kriwacki RW, Pappu RV, Brangwynne CP. Coexisting Liquid Phases Underlie Nucleolar Subcompartments. Cell. PMID 27212236 DOI: 10.1016/J.Cell.2016.04.047 |
0.379 |
|
| 2016 |
Das RK, Huang Y, Phillips AH, Kriwacki RW, Pappu RV. Cryptic sequence features within the disordered protein p27Kip1 regulate cell cycle signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27140628 DOI: 10.1073/Pnas.1516277113 |
0.355 |
|
| 2016 |
Csizmok V, Follis AV, Kriwacki RW, Forman-Kay JD. Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling. Chemical Reviews. PMID 26922996 DOI: 10.1021/Acs.Chemrev.5B00548 |
0.41 |
|
| 2016 |
Mitrea DM, Cika JA, Guy CS, Ban D, Banerjee PR, Stanley CB, Nourse A, Deniz AA, Kriwacki RW. Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA. Elife. 5. PMID 26836305 DOI: 10.7554/Elife.13571 |
0.416 |
|
| 2016 |
Grace CR, Ban D, Min J, Mayasundari A, Min L, Finch KE, Griffiths L, Bharatham N, Bashford D, Kiplin Guy R, Dyer MA, Kriwacki RW. Monitoring ligand-induced protein ordering in drug discovery. Journal of Molecular Biology. PMID 26812210 DOI: 10.1016/J.Jmb.2016.01.016 |
0.366 |
|
| 2016 |
Mitrea DM, Kriwacki RW. Phase separation in biology; functional organization of a higher order. Cell Communication and Signaling : Ccs. 14: 1. PMID 26727894 DOI: 10.1186/S12964-015-0125-7 |
0.357 |
|
| 2016 |
Banerjee PR, Mitrea DM, Kriwacki RW, Deniz A. Conformational Polymorphism in Conditionally Disordered Nucleophosmin: From Single-Molecules to Liquid Droplets Biophysical Journal. 110: 402a. DOI: 10.1016/J.Bpj.2015.11.2171 |
0.389 |
|
| 2015 |
Banerjee PR, Mitrea DM, Kriwacki RW, Deniz AA. Asymmetric Modulation of Protein Order-Disorder Transitions by Phosphorylation and Partner Binding. Angewandte Chemie (International Ed. in English). PMID 26679013 DOI: 10.1002/Anie.201507728 |
0.361 |
|
| 2015 |
Iconaru LI, Ban D, Bharatham K, Ramanathan A, Zhang W, Shelat AA, Zuo J, Kriwacki RW. Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1). Scientific Reports. 5: 15686. PMID 26507530 DOI: 10.1038/Srep15686 |
0.409 |
|
| 2015 |
Pettersson M, Quant M, Min J, Iconaru L, Kriwacki RW, Waddell MB, Guy RK, Luthman K, Grøtli M. Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction. Plos One. 10: e0137867. PMID 26427060 DOI: 10.1371/Journal.Pone.0137867 |
0.364 |
|
| 2015 |
Zheng J, Viacava Follis A, Kriwacki RW, Moldoveanu T. Discoveries and Controversies in BCL-2 Proteins-Mediated Apoptosis. The Febs Journal. PMID 26411300 DOI: 10.1111/Febs.13527 |
0.753 |
|
| 2015 |
Follis AV, Llambi F, Merritt P, Chipuk JE, Green DR, Kriwacki RW. Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis. Molecular Cell. 59: 677-84. PMID 26236013 DOI: 10.1016/J.Molcel.2015.06.029 |
0.351 |
|
| 2015 |
Joshi A, Iyengar R, Joo JH, Li-Harms XJ, Wright C, Marino R, Winborn BJ, Phillips A, Temirov J, Sciarretta S, Kriwacki R, Peng J, Shelat A, Kundu M. Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1. Cell Death and Differentiation. PMID 26138443 DOI: 10.1038/Cdd.2015.88 |
0.316 |
|
| 2015 |
Pettersson M, Bliman D, Jacobsson J, Nilsson JR, Min J, Iconaru L, Guy RK, Kriwacki RW, Andréasson J, Grøtli M. 8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction. Plos One. 10: e0124423. PMID 25942498 DOI: 10.1371/Journal.Pone.0124423 |
0.345 |
|
| 2015 |
Huang Y, Yoon MK, Otieno S, Lelli M, Kriwacki RW. The activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases. Journal of Molecular Biology. 427: 371-86. PMID 25463440 DOI: 10.1016/J.Jmb.2014.11.011 |
0.347 |
|
| 2014 |
Kriwacki RW. Protein dynamics: tuning disorder propensity in p53. Nature Chemical Biology. 10: 987-8. PMID 25393491 DOI: 10.1038/Nchembio.1692 |
0.366 |
|
| 2014 |
Follis AV, Llambi F, Ou L, Baran K, Green DR, Kriwacki RW. The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nature Structural & Molecular Biology. 21: 535-43. PMID 24814347 DOI: 10.1038/Nsmb.2829 |
0.369 |
|
| 2014 |
van der Lee R, Buljan M, Lang B, Weatheritt RJ, Daughdrill GW, Dunker AK, Fuxreiter M, Gough J, Gsponer J, Jones DT, Kim PM, Kriwacki RW, Oldfield CJ, Pappu RV, Tompa P, et al. Classification of intrinsically disordered regions and proteins. Chemical Reviews. 114: 6589-631. PMID 24773235 DOI: 10.1021/Cr400525M |
0.505 |
|
| 2014 |
Mitrea DM, Grace CR, Buljan M, Yun MK, Pytel NJ, Satumba J, Nourse A, Park CG, Madan Babu M, White SW, Kriwacki RW. Structural polymorphism in the N-terminal oligomerization domain of NPM1. Proceedings of the National Academy of Sciences of the United States of America. 111: 4466-71. PMID 24616519 DOI: 10.1073/Pnas.1321007111 |
0.381 |
|
| 2014 |
Moldoveanu T, Follis AV, Kriwacki RW, Green DR. Many players in BCL-2 family affairs. Trends in Biochemical Sciences. 39: 101-11. PMID 24503222 DOI: 10.1016/J.Tibs.2013.12.006 |
0.396 |
|
| 2014 |
Jakob U, Kriwacki R, Uversky VN. Conditionally and transiently disordered proteins: Awakening cryptic disorder to regulate protein function Chemical Reviews. 114: 6779-6805. PMID 24502763 DOI: 10.1021/Cr400459C |
0.333 |
|
| 2014 |
Varadi M, Kosol S, Lebrun P, Valentini E, Blackledge M, Dunker AK, Felli IC, Forman-Kay JD, Kriwacki RW, Pierattelli R, Sussman J, Svergun DI, Uversky VN, Vendruscolo M, Wishart D, et al. pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Research. 42: D326-35. PMID 24174539 DOI: 10.1093/Nar/Gkt960 |
0.497 |
|
| 2014 |
Follis AV, Grace C, Kriwacki R. Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Mej/Pdb |
0.324 |
|
| 2014 |
Kriwacki R. Control of Disorder and order in Signaling by Proteins Biophysical Journal. 106: 5a. DOI: 10.1016/J.Bpj.2013.11.060 |
0.376 |
|
| 2013 |
Frye JJ, Brown NG, Petzold G, Watson ER, Grace CR, Nourse A, Jarvis MA, Kriwacki RW, Peters JM, Stark H, Schulman BA. Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown. Nature Structural & Molecular Biology. 20: 827-35. PMID 23708605 DOI: 10.1038/Nsmb.2593 |
0.362 |
|
| 2013 |
Moldoveanu T, Grace CR, Llambi F, Nourse A, Fitzgerald P, Gehring K, Kriwacki RW, Green DR. BID-induced structural changes in BAK promote apoptosis. Nature Structural & Molecular Biology. 20: 589-97. PMID 23604079 DOI: 10.1038/Nsmb.2563 |
0.353 |
|
| 2013 |
Mitrea DM, Kriwacki RW. Regulated unfolding of proteins in signaling. Febs Letters. 587: 1081-8. PMID 23454209 DOI: 10.1016/J.Febslet.2013.02.024 |
0.329 |
|
| 2013 |
Follis AV, Chipuk JE, Fisher JC, Yun MK, Grace CR, Nourse A, Baran K, Ou L, Min L, White SW, Green DR, Kriwacki RW. PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nature Chemical Biology. 9: 163-8. PMID 23340338 DOI: 10.1038/Nchembio.1166 |
0.36 |
|
| 2013 |
Viacava Follis A, Kriwacki RW. Structural Studies of Cytoplasmic P53 Interactions Biophysical Journal. 104: 235a. DOI: 10.1016/J.Bpj.2012.11.1326 |
0.411 |
|
| 2013 |
Banerjee PR, Mitrea DM, Kriwacki RW, Deniz AA. Single-Molecule and Ensemble Fluorescence Study of Cryptic Disorder and Oligomerization in Nucleophosmin Biophysical Journal. 104: 190a. DOI: 10.1016/J.Bpj.2012.11.1071 |
0.338 |
|
| 2012 |
Otieno S, Kriwacki R. Probing the role of nascent helicity in p27 function as a cell cycle regulator. Plos One. 7: e47177. PMID 23071750 DOI: 10.1371/Journal.Pone.0047177 |
0.405 |
|
| 2012 |
Mitrea DM, Yoon MK, Ou L, Kriwacki RW. Disorder-function relationships for the cell cycle regulatory proteins p21 and p27. Biological Chemistry. 393: 259-74. PMID 23029651 DOI: 10.1515/Hsz-2011-0254 |
0.41 |
|
| 2012 |
Theillet FX, Smet-Nocca C, Liokatis S, Thongwichian R, Kosten J, Yoon MK, Kriwacki RW, Landrieu I, Lippens G, Selenko P. Cell signaling, post-translational protein modifications and NMR spectroscopy. Journal of Biomolecular Nmr. 54: 217-36. PMID 23011410 DOI: 10.1007/S10858-012-9674-X |
0.356 |
|
| 2012 |
Babu MM, Kriwacki RW, Pappu RV. Structural biology. Versatility from protein disorder. Science (New York, N.Y.). 337: 1460-1. PMID 22997313 DOI: 10.1126/Science.1228775 |
0.353 |
|
| 2012 |
Yoon MK, Mitrea DM, Ou L, Kriwacki RW. Cell cycle regulation by the intrinsically disordered proteins p21 and p27. Biochemical Society Transactions. 40: 981-8. PMID 22988851 DOI: 10.1042/Bst20120092 |
0.407 |
|
| 2012 |
Zhang J, Loyd MR, Randall MS, Waddell MB, Kriwacki RW, Ney PA. A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes. Autophagy. 8: 1325-32. PMID 22906961 DOI: 10.4161/Auto.20764 |
0.335 |
|
| 2012 |
Ganguly D, Otieno S, Waddell B, Iconaru L, Kriwacki RW, Chen J. Electrostatically accelerated coupled binding and folding of intrinsically disordered proteins. Journal of Molecular Biology. 422: 674-84. PMID 22721951 DOI: 10.1016/J.Jmb.2012.06.019 |
0.394 |
|
| 2012 |
Follis AV, Galea CA, Kriwacki RW. Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics. Advances in Experimental Medicine and Biology. 725: 27-49. PMID 22399317 DOI: 10.1007/978-1-4614-0659-4_3 |
0.411 |
|
| 2012 |
Ou L, Waddell MB, Kriwacki RW. Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1). Acs Chemical Biology. 7: 678-82. PMID 22276948 DOI: 10.1021/Cb200487H |
0.371 |
|
| 2012 |
Iconaru LI, Shelat A, Zuo J, Kriwacki RW. A Quest for Small Molecule Inhibitors of the Cell Cycle Regulator, P27 Biophysical Journal. 102: 635a. DOI: 10.1016/J.Bpj.2011.11.3455 |
0.369 |
|
| 2012 |
Ou L, Kriwacki R. Sequential Tyrosine Phosphorylation of P27Kip1 When Bound to the Cdk4/Cyclin D1 Complex Promotes Kinase Activity Biophysical Journal. 102: 634a. DOI: 10.1016/J.Bpj.2011.11.3453 |
0.33 |
|
| 2012 |
Viacava Follis A, Kriwacki RW. Functional Regulation of the Anti-Apoptotic Protein BCL-xL through Post-Translational Modification of its Intrinsically Disordered Loop Biophysical Journal. 102: 633a. DOI: 10.1016/J.Bpj.2011.11.3446 |
0.379 |
|
| 2011 |
Kriwacki RW, Yoon MK. Cell biology. Fishing in the nuclear pore. Science (New York, N.Y.). 333: 44-5. PMID 21719663 DOI: 10.1126/Science.1208568 |
0.363 |
|
| 2011 |
Ou L, Ferreira AM, Otieno S, Xiao L, Bashford D, Kriwacki RW. Incomplete folding upon binding mediates Cdk4/cyclin D complex activation by tyrosine phosphorylation of inhibitor p27 protein. The Journal of Biological Chemistry. 286: 30142-51. PMID 21715330 DOI: 10.1074/Jbc.M111.244095 |
0.345 |
|
| 2011 |
Otieno S, Grace CR, Kriwacki RW. The role of the LH subdomain in the function of the Cip/Kip cyclin-dependent kinase regulators. Biophysical Journal. 100: 2486-94. PMID 21575583 DOI: 10.1016/J.Bpj.2011.04.014 |
0.385 |
|
| 2011 |
Dunker AK, Kriwacki RW. The orderly chaos of proteins. Scientific American. 304: 68-73. PMID 21495485 DOI: 10.1038/Scientificamerican0411-68 |
0.367 |
|
| 2011 |
Wang Y, Fisher JC, Mathew R, Ou L, Otieno S, Sublet J, Xiao L, Chen J, Roussel MF, Kriwacki RW. Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21. Nature Chemical Biology. 7: 214-21. PMID 21358637 DOI: 10.1038/Nchembio.536 |
0.405 |
|
| 2010 |
Scott DC, Monda JK, Grace CR, Duda DM, Kriwacki RW, Kurz T, Schulman BA. A dual E3 mechanism for Rub1 ligation to Cdc53. Molecular Cell. 39: 784-96. PMID 20832729 DOI: 10.1016/J.Molcel.2010.08.030 |
0.303 |
|
| 2009 |
Galea CA, High AA, Obenauer JC, Mishra A, Park CG, Punta M, Schlessinger A, Ma J, Rost B, Slaughter CA, Kriwacki RW. Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome. Journal of Proteome Research. 8: 211-26. PMID 19067583 DOI: 10.1021/Pr800308V |
0.396 |
|
| 2008 |
Chipuk JE, Fisher JC, Dillon CP, Kriwacki RW, Kuwana T, Green DR. Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 20327-32. PMID 19074266 DOI: 10.1073/Pnas.0808036105 |
0.347 |
|
| 2008 |
Sivakolundu SG, Nourse A, Moshiach S, Bothner B, Ashley C, Satumba J, Lahti J, Kriwacki RW. Intrinsically unstructured domains of Arf and Hdm2 form bimolecular oligomeric structures in vitro and in vivo. Journal of Molecular Biology. 384: 240-54. PMID 18809412 DOI: 10.1016/J.Jmb.2008.09.019 |
0.395 |
|
| 2008 |
Galea CA, Wang Y, Sivakolundu SG, Kriwacki RW. Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits. Biochemistry. 47: 7598-609. PMID 18627125 DOI: 10.1021/Bi8006803 |
0.407 |
|
| 2008 |
Galea CA, Nourse A, Wang Y, Sivakolundu SG, Heller WT, Kriwacki RW. Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27 Kip1. Journal of Molecular Biology. 376: 827-38. PMID 18177895 DOI: 10.1016/J.Jmb.2007.12.016 |
0.368 |
|
| 2007 |
Kerr ID, Sivakolundu S, Li Z, Buchsbaum JC, Knox LA, Kriwacki R, White SW. Crystallographic and NMR analyses of UvsW and UvsW.1 from bacteriophage T4 Journal of Biological Chemistry. 282: 34392-34400. PMID 17878153 DOI: 10.1074/Jbc.M705900200 |
0.354 |
|
| 2007 |
Pham TC, Kriwacki RW, Parrill AL. Peptide design and structural characterization of a GPCR loop mimetic. Biopolymers. 86: 298-310. PMID 17443712 DOI: 10.1002/Bip.20745 |
0.301 |
|
| 2007 |
Zhan J, Easton JB, Huang S, Mishra A, Xiao L, Lacy ER, Kriwacki RW, Houghton PJ. Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo. Molecular and Cellular Biology. 27: 3530-41. PMID 17325029 DOI: 10.1128/Mcb.00086-06 |
0.352 |
|
| 2007 |
Grimmler M, Wang Y, Mund T, Cilensek Z, Keidel EM, Waddell MB, Jäkel H, Kullmann M, Kriwacki RW, Hengst L. Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell. 128: 269-80. PMID 17254966 DOI: 10.1016/J.Cell.2006.11.047 |
0.305 |
|
| 2006 |
Galea CA, Pagala VR, Obenauer JC, Park CG, Slaughter CA, Kriwacki RW. Proteomic studies of the intrinsically unstructured mammalian proteome. Journal of Proteome Research. 5: 2839-48. PMID 17022655 DOI: 10.1021/Pr060328C |
0.349 |
|
| 2006 |
Jordan JB, Kovacs H, Wang Y, Mobli M, Luo R, Anklin C, Hoch JC, Kriwacki RW. Three-dimensional 13C-detected CH3-TOCSY using selectively protonated proteins: facile methyl resonance assignment and protein structure determination. Journal of the American Chemical Society. 128: 9119-28. PMID 16834385 DOI: 10.1021/Ja058587A |
0.302 |
|
| 2006 |
West AN, Ribeiro RC, Jenkins J, Rodriguez-Galindo C, Figueiredo BC, Kriwacki R, Zambetti GP. Identification of a novel germ line variant hotspot mutant p53-R175L in pediatric adrenal cortical carcinoma. Cancer Research. 66: 5056-62. PMID 16707427 DOI: 10.1158/0008-5472.Can-05-4580 |
0.309 |
|
| 2006 |
Bowman P, Galea CA, Lacy E, Kriwacki RW. Thermodynamic characterization of interactions between p27(Kip1) and activated and non-activated Cdk2: intrinsically unstructured proteins as thermodynamic tethers. Biochimica Et Biophysica Acta. 1764: 182-9. PMID 16458085 DOI: 10.1016/J.Bbapap.2005.12.016 |
0.369 |
|
| 2005 |
Wang Y, Filippov I, Richter C, Luo R, Kriwacki RW. Solution NMR studies of an intrinsically unstructured protein within a dilute, 75 kDa eukaryotic protein assembly; probing the practical limits for efficiently assigning polypeptide backbone resonances. Chembiochem : a European Journal of Chemical Biology. 6: 2242-6. PMID 16270364 DOI: 10.1002/Cbic.200500260 |
0.368 |
|
| 2005 |
Galea C, Bowman P, Kriwacki RW. Disruption of an intermonomer salt bridge in the p53 tetramerization domain results in an increased propensity to form amyloid fibrils. Protein Science : a Publication of the Protein Society. 14: 2993-3003. PMID 16260757 DOI: 10.1110/Ps.051622005 |
0.347 |
|
| 2005 |
Sivakolundu SG, Bashford D, Kriwacki RW. Disordered p27Kip1 exhibits intrinsic structure resembling the Cdk2/cyclin A-bound conformation. Journal of Molecular Biology. 353: 1118-28. PMID 16214166 DOI: 10.1016/J.Jmb.2005.08.074 |
0.402 |
|
| 2005 |
Luo R, Mann B, Tuomanen E, Kriwacki RW. NMR assignment of the R2 domain of pneumococcal choline binding protein A (CbpA). Journal of Biomolecular Nmr. 32: 93. PMID 16041490 DOI: 10.1007/S10858-005-3657-0 |
0.32 |
|
| 2005 |
Lacy ER, Wang Y, Post J, Nourse A, Webb W, Mapelli M, Musacchio A, Siuzdak G, Kriwacki RW. Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division. Journal of Molecular Biology. 349: 764-73. PMID 15890360 DOI: 10.1016/J.Jmb.2005.04.019 |
0.381 |
|
| 2005 |
Luo R, Mann B, Lewis WS, Rowe A, Heath R, Stewart ML, Hamburger AE, Sivakolundu S, Lacy ER, Bjorkman PJ, Tuomanen E, Kriwacki RW. Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae. The Embo Journal. 24: 34-43. PMID 15616594 DOI: 10.1038/Sj.Emboj.7600490 |
0.347 |
|
| 2004 |
Lacy ER, Filippov I, Lewis WS, Otieno S, Xiao L, Weiss S, Hengst L, Kriwacki RW. p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding. Nature Structural & Molecular Biology. 11: 358-64. PMID 15024385 DOI: 10.1038/Nsmb746 |
0.404 |
|
| 2004 |
Kriwacki R, Reisdorph N, Siuzdak G. Protein structure characterization with mass spectrometry Spectroscopy. 18: 37-47. DOI: 10.1155/2004/407960 |
0.365 |
|
| 2003 |
Bothner B, Aubin Y, Kriwacki RW. Peptides derived from two dynamically disordered proteins self-assemble into amyloid-like fibrils. Journal of the American Chemical Society. 125: 3200-1. PMID 12630860 DOI: 10.1021/Ja028265W |
0.321 |
|
| 2002 |
DiGiammarino EL, Lee AS, Cadwell C, Zhang W, Bothner B, Ribeiro RC, Zambetti G, Kriwacki RW. A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer. Nature Structural Biology. 9: 12-6. PMID 11753428 DOI: 10.1038/Nsb730 |
0.315 |
|
| 2001 |
Bothner B, Lewis WS, DiGiammarino EL, Weber JD, Bothner SJ, Kriwacki RW. Defining the molecular basis of Arf and Hdm2 interactions. Journal of Molecular Biology. 314: 263-77. PMID 11718560 DOI: 10.1006/Jmbi.2001.5110 |
0.425 |
|
| 2001 |
DiGiammarino EL, Filippov I, Weber JD, Bothner B, Kriwacki RW. Solution structure of the p53 regulatory domain of the p19Arf tumor suppressor protein. Biochemistry. 40: 2379-86. PMID 11327858 DOI: 10.1021/Bi0024005 |
0.401 |
|
| 2001 |
Li N, Zhang W, White SW, Kriwacki RW. Solution structure of the transcriptional activation domain of the bacteriophage T4 protein, MotA. Biochemistry. 40: 4293-302. PMID 11284685 DOI: 10.1021/Bi0028284 |
0.351 |
|
| 2000 |
Kriwacki RW, Siuzdak G. Probing protein-protein interactions with mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 146: 223-38. PMID 10948505 DOI: 10.1385/1-59259-045-4:223 |
0.34 |
|
| 2000 |
Kriwacki RW, Legge GB, Hommel U, Ramage P, Chung J, Tennant LL, Wright PE, Dyson HJ. Assignment of 1H, 13C and 15N resonances of the I-domain of human leukocyte function associated antigen-1. Journal of Biomolecular Nmr. 16: 271-2. PMID 10805135 DOI: 10.1023/A:1008358912334 |
0.357 |
|
| 2000 |
Weber JD, Kuo ML, Bothner B, DiGiammarino EL, Kriwacki RW, Roussel MF, Sherr CJ. Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex. Molecular and Cellular Biology. 20: 2517-28. PMID 10713175 DOI: 10.1128/Mcb.20.7.2517-2528.2000 |
0.41 |
|
| 2000 |
Legge GB, Kriwacki RW, Chung J, Hommel U, Ramage P, Case DA, Dyson HJ, Wright PE. NMR solution structure of the inserted domain of human leukocyte function associated antigen-1. Journal of Molecular Biology. 295: 1251-64. PMID 10653701 DOI: 10.1006/Jmbi.1999.3409 |
0.501 |
|
| 1999 |
Kallen J, Welzenbach K, Ramage P, Geyl D, Kriwacki R, Legge G, Cottens S, Weitz-Schmidt G, Hommel U. Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain Journal of Molecular Biology. 292: 1-9. PMID 10493852 DOI: 10.1006/Jmbi.1999.3047 |
0.314 |
|
| 1998 |
Long JJ, Leresche A, Kriwacki RW, Gottesfeld JM. Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis. Molecular and Cellular Biology. 18: 1467-76. PMID 9488463 DOI: 10.1128/Mcb.18.3.1467 |
0.33 |
|
| 1997 |
Kriwacki RW, Wu J, Tennant L, Wright PE, Siuzdak G. Probing protein structure using biochemical and biophysical methods. Proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21Waf1/Cip1/Sdi1. Journal of Chromatography. A. 777: 23-30. PMID 9297835 DOI: 10.1016/S0021-9673(97)00527-X |
0.521 |
|
| 1997 |
Narayan VA, Kriwacki RW, Caradonna JP. Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein-DNA recognition. The Journal of Biological Chemistry. 272: 7801-9. PMID 9065444 DOI: 10.1074/Jbc.272.12.7801 |
0.638 |
|
| 1996 |
Kriwacki RW, Hengst L, Tennant L, Reed SI, Wright PE. Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity. Proceedings of the National Academy of Sciences of the United States of America. 93: 11504-9. PMID 8876165 DOI: 10.1073/Pnas.93.21.11504 |
0.552 |
|
| 1996 |
Kriwacki RW, Wu J, Siuzdak G, Wright PE. Probing protein/protein interactions with mass spectrometry and isotopic labeling: Analysis of the p21/Cdk2 complex Journal of the American Chemical Society. 118: 5320-5321. DOI: 10.1021/Ja960752M |
0.535 |
|
| 1993 |
Kriwacki RW, Hill RB, Flanagan JM, Caradonna JP, Prestegard JH. New NMR methods for the characterization of bound waters in macromolecules Journal of the American Chemical Society. 115: 8907-8911. DOI: 10.1021/Ja00073A003 |
0.635 |
|
| 1992 |
Kriwacki RW, Schultz SC, Steitz TA, Caradonna JP. Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp1. Proceedings of the National Academy of Sciences of the United States of America. 89: 9759-63. PMID 1329106 DOI: 10.1073/Pnas.89.20.9759 |
0.624 |
|
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