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J. M. Younger, Ph.D. - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Protein Folding, Molecular Chaperones, Mitochondria, Intermediate Metabolism
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Younger JM, Chen L, Ren HY, Rosser MF, Turnbull EL, Fan CY, Patterson C, Cyr DM. Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator. Cell. 126: 571-82. PMID 16901789 DOI: 10.1016/J.Cell.2006.06.041  0.572
2005 Dai Q, Qian SB, Li HH, McDonough H, Borchers C, Huang D, Takayama S, Younger JM, Ren HY, Cyr DM, Patterson C. Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. The Journal of Biological Chemistry. 280: 38673-81. PMID 16169850 DOI: 10.1074/Jbc.M507986200  0.543
2005 Younger JM, Fan CY, Chen L, Rosser MF, Patterson C, Cyr DM. Cystic fibrosis transmembrane conductance regulator as a model substrate to study endoplasmic reticulum protein quality control in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 301: 293-303. PMID 15917641 DOI: 10.1385/1-59259-895-1:293  0.585
2004 Younger JM, Ren HY, Chen L, Fan CY, Fields A, Patterson C, Cyr DM. A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase. The Journal of Cell Biology. 167: 1075-85. PMID 15611333 DOI: 10.1083/Jcb.200410065  0.572
2002 Lee S, Fan CY, Younger JM, Ren H, Cyr DM. Identification of essential residues in the type II Hsp40 Sis1 that function in polypeptide binding. The Journal of Biological Chemistry. 277: 21675-82. PMID 11919183 DOI: 10.1074/jbc.M111075200  0.493
2001 Meacham GC, Patterson C, Zhang W, Younger JM, Cyr DM. The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation. Nature Cell Biology. 3: 100-5. PMID 11146634 DOI: 10.1038/35050509  0.589
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