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Paul J. Lombroso, MD - Publications

Affiliations: 
Child Study Center and Departments of Neurobiology and Psychiatry Yale University, New Haven, CT 
Area:
molecular psychiatry
Website:
http://medicine.yale.edu/labs/lombroso/

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Year Citation  Score
2020 Chatterjee M, Singh P, Xu J, Lombroso PJ, Kurup PK. Inhibition of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Activity Reverses Behavioral Deficits in a Rodent Model of Autism. Behavioural Brain Research. 112713. PMID 32461127 DOI: 10.1016/j.bbr.2020.112713  0.429
2019 Mallozzi C, Pepponi R, Visentin S, Chiodi V, Lombroso PJ, Bader M, Popoli P, Domenici MR. The activity of the STriatal-Enriched protein tyrosine Phosphatase (STEP) in neuronal cells is modulated by adenosine A receptor. Journal of Neurochemistry. PMID 31520531 DOI: 10.1111/jnc.14866  0.394
2019 Dedek A, Xu J, Kandegedara CM, Lorenzo LÉ, Godin AG, De Koninck Y, Lombroso PJ, Tsai EC, Hildebrand ME. Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing. Brain : a Journal of Neurology. 142: 1535-1546. PMID 31135041 DOI: 10.1093/Brain/Awz105  0.328
2018 Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J. The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline. Current Biology : Cb. PMID 29576474 DOI: 10.1016/J.Cub.2018.02.047  0.512
2018 Bosco F, Valente P, Milanese M, Piccini A, Messa M, Bonanno G, Lombroso P, Baldelli P, Benfenati F, Giovedì S. Altered Intracellular Calcium Homeostasis Underlying Enhanced Glutamatergic Transmission in Striatal-Enriched Tyrosine Phosphatase (STEP) Knockout Mice. Molecular Neurobiology. PMID 29508281 DOI: 10.1007/S12035-018-0980-5  0.593
2017 Tjin CC, Otley KD, Baguley TD, Kurup P, Xu J, Nairn AC, Lombroso PJ, Ellman JA. Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases. Acs Central Science. 3: 1322-1328. PMID 29296673 DOI: 10.1021/Acscentsci.7B00486  0.53
2017 Witten MR, Wissler L, Snow M, Geschwindner S, Read JA, Brandon NJ, Nairn AC, Lombroso PJ, Käck H, Ellman JA. X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors. Journal of Medicinal Chemistry. PMID 29116812 DOI: 10.1021/Acs.Jmedchem.7B01292  0.541
2017 Chatterjee M, Kurup PK, Lundbye CJ, Hugger Toft AK, Kwon J, Benedict J, Kamceva M, Banke TG, Lombroso PJ. STEP inhibition reverses behavioral, electrophysiologic, and synaptic abnormalities in Fmr1 KO mice. Neuropharmacology. PMID 28943283 DOI: 10.1016/j.neuropharm.2017.09.026  0.422
2017 Xu J, Kurup P, Nairn AC, Lombroso PJ. Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP61. Molecular Neurobiology. PMID 28466270 DOI: 10.1007/s12035-017-0555-x  0.59
2017 Siemsen BM, Lombroso PJ, McGinty JF. Intra-prelimbic cortical inhibition of striatal-enriched tyrosine phosphatase suppresses cocaine seeking in rats. Addiction Biology. PMID 28349660 DOI: 10.1111/adb.12504  0.737
2016 Lombroso PJ, Ogren M, Kurup P, Nairn AC. Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity. F1000research. 5. PMID 29098072 DOI: 10.12688/f1000research.8571.1  0.601
2016 Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing. Cell Reports. 17: 2753-2765. PMID 27926876 DOI: 10.1016/J.Celrep.2016.11.024  0.355
2016 Tian M, Xu J, Lei G, Lombroso PJ, Jackson MF, MacDonald JF. STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit. Scientific Reports. 6: 36684. PMID 27857196 DOI: 10.1038/srep36684  0.385
2016 Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, ... ... Lombroso PJ, et al. Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models. Molecular Psychiatry. PMID 27752082 DOI: 10.1038/mp.2016.163  0.557
2016 Kamceva M, Benedict J, Nairn AC, Lombroso PJ. Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function. Neural Plasticity. 2016: 8136925. PMID 27190655 DOI: 10.1155/2016/8136925  0.604
2015 Xu J, Kurup P, Baguley TD, Foscue E, Ellman JA, Nairn AC, Lombroso PJ. Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice. Cellular and Molecular Life Sciences : Cmls. PMID 26450419 DOI: 10.1007/S00018-015-2057-1  0.554
2015 Jang SS, Royston SE, Xu J, Cavaretta JP, Vest MO, Lee KY, Lee S, Jeong HG, Lombroso PJ, Chung HJ. Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity. Molecular Brain. 8: 55. PMID 26391783 DOI: 10.1186/S13041-015-0148-4  0.799
2015 Xu J, Kurup P, Azkona G, Baguley TD, Saavedra A, Nairn AC, Ellman JA, Pérez-Navarro E, Lombroso PJ. Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels. Journal of Neurochemistry. PMID 26316048 DOI: 10.1111/Jnc.13295  0.585
2015 Azkona G, Saavedra A, Aira Z, Aluja D, Xifró X, Baguley T, Alberch J, Ellman JA, Lombroso PJ, Azkue JJ, Pérez-Navarro E. STEP modulates nociception: evidences from genetic deletion and pharmacological inhibition. Pain. PMID 26270590 DOI: 10.1097/J.Pain.0000000000000329  0.325
2015 Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Molecular Neurobiology. PMID 26223799 DOI: 10.1007/S12035-015-9335-7  0.43
2015 Legastelois R, Darcq E, Wegner SA, Lombroso PJ, Ron D. Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking. Plos One. 10: e0127408. PMID 25992601 DOI: 10.1371/Journal.Pone.0127408  0.335
2015 Xu J, Kurup P, Foscue E, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway. Journal of Neurochemistry. 134: 629-41. PMID 25951993 DOI: 10.1111/jnc.13160  0.451
2015 Baguley TD, Nairn AC, Lombroso PJ, Ellman JA. Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP. Bioorganic & Medicinal Chemistry Letters. 25: 1044-6. PMID 25666825 DOI: 10.1016/J.Bmcl.2015.01.020  0.529
2015 Kurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ, Nairn AC. STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: 1202-7. PMID 25583483 DOI: 10.1073/pnas.1417423112  0.523
2014 Ng AN, Doherty AJ, Lombroso PJ, Emptage NJ, Collingridge GL. Rapid regulation of endoplasmic reticulum dynamics in dendritic spines by NMDA receptor activation. Molecular Brain. 7: 60. PMID 25242397 DOI: 10.1186/s13041-014-0060-3  0.343
2014 Karasawa T, Lombroso PJ. Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disorders. Neuroscience Research. 89: 1-9. PMID 25218562 DOI: 10.1016/J.Neures.2014.08.018  0.421
2014 Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, ... ... Lombroso PJ, et al. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. Plos Biology. 12: e1001923. PMID 25093460 DOI: 10.1371/Journal.Pbio.1001923  0.654
2014 Gladding CM, Fan J, Zhang LY, Wang L, Xu J, Li EH, Lombroso PJ, Raymond LA. Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model. Journal of Neurochemistry. 130: 145-59. PMID 24588402 DOI: 10.1111/Jnc.12700  0.455
2014 Chiodi V, Mallozzi C, Ferrante A, Chen JF, Lombroso PJ, Di Stasi AM, Popoli P, Domenici MR. Cocaine-induced changes of synaptic transmission in the striatum are modulated by adenosine A2A receptors and involve the tyrosine phosphatase STEP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 569-78. PMID 23989619 DOI: 10.1038/npp.2013.229  0.349
2013 Deb I, Manhas N, Poddar R, Rajagopal S, Allan AM, Lombroso PJ, Rosenberg GA, Candelario-Jalil E, Paul S. Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17814-26. PMID 24198371 DOI: 10.1523/Jneurosci.2346-12.2013  0.348
2013 Baguley TD, Xu HC, Chatterjee M, Nairn AC, Lombroso PJ, Ellman JA. Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase. Journal of Medicinal Chemistry. 56: 7636-50. PMID 24083656 DOI: 10.1021/Jm401037H  0.596
2013 Dabrowska J, Hazra R, Guo JD, Li C, Dewitt S, Xu J, Lombroso PJ, Rainnie DG. Striatal-enriched protein tyrosine phosphatase-STEPs toward understanding chronic stress-induced activation of corticotrophin releasing factor neurons in the rat bed nucleus of the stria terminalis. Biological Psychiatry. 74: 817-26. PMID 24012328 DOI: 10.1016/J.Biopsych.2013.07.032  0.411
2012 Johnson MA, Lombroso PJ. A common STEP in the synaptic pathology of diverse neuropsychiatric disorders. The Yale Journal of Biology and Medicine. 85: 481-90. PMID 23239949  0.362
2012 Olausson P, Venkitaramani DV, Moran TD, Salter MW, Taylor JR, Lombroso PJ. The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity. Neuroscience. 225: 1-8. PMID 22885232 DOI: 10.1016/j.neuroscience.2012.07.069  0.785
2012 Xu J, Kurup P, Nairn AC, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 303-25. PMID 22840751 DOI: 10.1016/B978-0-12-394816-8.00009-X  0.544
2012 Carty NC, Xu J, Kurup P, Brouillette J, Goebel-Goody SM, Austin DR, Yuan P, Chen G, Correa PR, Haroutunian V, Pittenger C, Lombroso PJ. The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications. Translational Psychiatry. 2: e137. PMID 22781170 DOI: 10.1038/Tp.2012.63  0.434
2012 Pelov I, Teltsh O, Greenbaum L, Rigbi A, Kanyas-Sarner K, Lerer B, Lombroso P, Kohn Y. Involvement of PTPN5, the gene encoding the striatal-enriched protein tyrosine phosphatase, in schizophrenia and cognition Psychiatric Genetics. 22: 168-176. PMID 22555153 DOI: 10.1097/YPG.0b013e3283518586  0.351
2012 Xu J, Kurup P, Bartos JA, Patriarchi T, Hell JW, Lombroso PJ. Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity. The Journal of Biological Chemistry. 287: 20942-56. PMID 22544749 DOI: 10.1074/Jbc.M112.368654  0.426
2012 Gladding CM, Sepers MD, Xu J, Zhang LY, Milnerwood AJ, Lombroso PJ, Raymond LA. Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model. Human Molecular Genetics. 21: 3739-52. PMID 22523092 DOI: 10.1093/hmg/dds154  0.467
2012 Goebel-Goody SM, Wilson-Wallis ED, Royston S, Tagliatela SM, Naegele JR, Lombroso PJ. Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model. Genes, Brain, and Behavior. 11: 586-600. PMID 22405502 DOI: 10.1111/J.1601-183X.2012.00781.X  0.786
2012 Braithwaite SP, Stock JB, Lombroso PJ, Nairn AC. Protein phosphatases and Alzheimer's disease. Progress in Molecular Biology and Translational Science. 106: 343-79. PMID 22340724 DOI: 10.1016/B978-0-12-396456-4.00012-2  0.536
2012 Goebel-Goody SM, Baum M, Paspalas CD, Fernandez SM, Carty NC, Kurup P, Lombroso PJ. Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders. Pharmacological Reviews. 64: 65-87. PMID 22090472 DOI: 10.1124/pr.110.003053  0.48
2012 Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, ... ... Lombroso PJ, et al. Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation. Acs Chemical Biology. 7: 367-77. PMID 22070201 DOI: 10.1021/Cb2004274  0.325
2012 Goebel-Goody SM, Lombroso PJ. Taking STEPs forward to understand fragile X syndrome. Results and Problems in Cell Differentiation. 54: 223-41. PMID 22009355 DOI: 10.1007/978-3-642-21649-7_12  0.48
2011 Zhang Y, Kurup P, Xu J, Anderson GM, Greengard P, Nairn AC, Lombroso PJ. Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization. Journal of Neurochemistry. 119: 664-72. PMID 21883219 DOI: 10.1111/j.1471-4159.2011.07450.x  0.64
2011 Moura PJ, Venkitaramani DV, Tashev R, Lombroso PJ, Xavier GF. Transport of animals between rooms: a little-noted aspect of laboratory procedure that may interfere with memory. Behavioural Processes. 88: 12-9. PMID 21729741 DOI: 10.1016/j.beproc.2011.06.008  0.711
2011 Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8150-62. PMID 21632937 DOI: 10.1523/Jneurosci.3446-10.2011  0.439
2011 Venkitaramani DV, Moura PJ, Picciotto MR, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory. The European Journal of Neuroscience. 33: 2288-98. PMID 21501258 DOI: 10.1111/j.1460-9568.2011.07687.x  0.808
2011 Hicklin TR, Wu PH, Radcliffe RA, Freund RK, Goebel-Goody SM, Correa PR, Proctor WR, Lombroso PJ, Browning MD. Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 108: 6650-5. PMID 21464302 DOI: 10.1073/Pnas.1017856108  0.526
2011 Briggs SW, Walker J, Asik K, Lombroso P, Naegele J, Aaron G. STEP regulation of seizure thresholds in the hippocampus. Epilepsia. 52: 497-506. PMID 21204826 DOI: 10.1111/J.1528-1167.2010.02912.X  0.608
2010 Baum ML, Kurup P, Xu J, Lombroso PJ. A STEP forward in neural function and degeneration. Communicative & Integrative Biology. 3: 419-22. PMID 21057629 DOI: 10.4161/cib.3.5.12692  0.48
2010 Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC, Lombroso PJ. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 107: 19014-9. PMID 20956308 DOI: 10.1073/pnas.1013543107  0.64
2010 Kurup P, Zhang Y, Venkitaramani DV, Xu J, Lombroso PJ. The role of STEP in Alzheimer's disease. Channels (Austin, Tex.). 4: 347-50. PMID 20699650 DOI: 10.1523/Jneurosci.0157-10.2010  0.779
2010 Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5948-57. PMID 20427654 DOI: 10.1523/JNEUROSCI.0157-10.2010  0.799
2010 Kurup P, Zhang Y, Venkitaramani DV, Xu J, Lombroso PJ. The role of STEP in Alzheimer disease Channels. 4.  0.712
2009 Xu J, Kurup P, Zhang Y, Goebel-Goody SM, Wu PH, Hawasli AH, Baum ML, Bibb JA, Lombroso PJ. Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9330-43. PMID 19625523 DOI: 10.1523/Jneurosci.2212-09.2009  0.676
2009 Chen J, Rusnak M, Lombroso PJ, Sidhu A. Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. The European Journal of Neuroscience. 29: 287-306. PMID 19200235 DOI: 10.1111/J.1460-9568.2008.06590.X  0.38
2009 Paspalas CD, Perley CC, Venkitaramani DV, Goebel-Goody SM, Zhang Y, Kurup P, Mattis JH, Lombroso PJ. Major vault protein is expressed along the nucleus-neurite axis and associates with mRNAs in cortical neurons. Cerebral Cortex (New York, N.Y. : 1991). 19: 1666-77. PMID 19029061 DOI: 10.1093/cercor/bhn203  0.752
2009 Tashev R, Moura PJ, Venkitaramani DV, Prosperetti C, Centonze D, Paul S, Lombroso PJ. A substrate trapping mutant form of striatal-enriched protein tyrosine phosphatase prevents amphetamine-induced stereotypies and long-term potentiation in the striatum. Biological Psychiatry. 65: 637-45. PMID 19026408 DOI: 10.1016/J.Biopsych.2008.10.008  0.758
2009 Venkitaramani DV, Paul S, Zhang Y, Kurup P, Ding L, Tressler L, Allen M, Sacca R, Picciotto MR, Lombroso PJ. Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation. Synapse (New York, N.Y.). 63: 69-81. PMID 18932218 DOI: 10.1002/syn.20608  0.799
2008 Lombroso PJ, Ogren MP. Learning and memory, part I: brain regions involved in two types of learning and memory. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 1228-32. PMID 18931610 DOI: 10.1097/CHI.0b013e318186e638  0.345
2008 Zhang Y, Venkitaramani DV, Gladding CM, Zhang Y, Kurup P, Molnar E, Collingridge GL, Lombroso PJ. The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10561-6. PMID 18923032 DOI: 10.1523/Jneurosci.2666-08.2008  0.79
2008 Ogren MP, Lombroso PJ. Reversing the effects of fragile X syndrome. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 863-7. PMID 18645420 DOI: 10.1097/CHI.0b0 13e318179a057  0.328
2008 Braithwaite SP, Xu J, Leung J, Urfer R, Nikolich K, Oksenberg D, Lombroso PJ, Shamloo M. Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. The European Journal of Neuroscience. 27: 2444-52. PMID 18445231 DOI: 10.1111/J.1460-9568.2008.06209.X  0.39
2008 Wu PH, Freund RK, Procotor WR, Goebel-Goody SM, Browning MD, Lombroso PJ. STriatal Enriched Protein Tyrosine Phosphatase mediates Ethanol inhibition of NMDA Receptor Activity Nature Precedings. DOI: 10.1038/Npre.2008.2473.1  0.375
2007 Venkitaramani DV, Chin J, Netzer WJ, Gouras GK, Lesne S, Malinow R, Lombroso PJ. Beta-amyloid modulation of synaptic transmission and plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11832-7. PMID 17978019 DOI: 10.1523/Jneurosci.3478-07.2007  0.73
2007 Hu Y, Zhang Y, Venkitaramani DV, Lombroso PJ. Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation. Journal of Neurochemistry. 103: 531-41. PMID 17623046 DOI: 10.1111/j.1471-4159.2007.04749.x  0.774
2007 Venkitaramani DV, Lombroso PJ. Molecular basis of genetic neuropsychiatric disorders. Child and Adolescent Psychiatric Clinics of North America. 16: 541-56. PMID 17562578 DOI: 10.1016/j.chc.2007.03.003  0.722
2007 Choi YS, Lin SL, Lee B, Kurup P, Cho HY, Naegele JR, Lombroso PJ, Obrietan K. Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2999-3009. PMID 17360923 DOI: 10.1523/Jneurosci.4913-06.2007  0.656
2007 Paul S, Olausson P, Venkitaramani DV, Ruchkina I, Moran TD, Tronson N, Mills E, Hakim S, Salter MW, Taylor JR, Lombroso PJ. The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala. Biological Psychiatry. 61: 1049-61. PMID 17081505 DOI: 10.1016/j.biopsych.2006.08.005  0.772
2006 Kansy JW, Katsovich L, McIver KS, Pick J, Zabriskie JB, Lombroso PJ, Leckman JF, Bibb JA. Identification of pyruvate kinase as an antigen associated with Tourette syndrome. Journal of Neuroimmunology. 181: 165-76. PMID 17011640 DOI: 10.1016/j.jneuroim.2006.08.007  0.601
2006 Braithwaite SP, Paul S, Nairn AC, Lombroso PJ. Synaptic plasticity: one STEP at a time. Trends in Neurosciences. 29: 452-8. PMID 16806510 DOI: 10.1016/j.tins.2006.06.007  0.594
2005 Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nature Neuroscience. 8: 1051-8. PMID 16025111 DOI: 10.1038/Nn1503  0.704
2005 Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P, Hervé D, Girault JA. Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 102: 491-6. PMID 15608059 DOI: 10.1073/Pnas.0408305102  0.736
2004 Lombroso P. Learning and memory | Aprendizado e memória Revista Brasileira De Psiquiatria. 26: 207-210. PMID 15645067 DOI: 10.1590/S1516-44462004000300011  0.322
2004 Nika K, Hyunh H, Williams S, Paul S, Bottini N, Taskén K, Lombroso PJ, Mustelin T. Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location. The Biochemical Journal. 378: 335-42. PMID 14613483 DOI: 10.1042/Bj20031244  0.344
2003 Paul S, Lombroso PJ. Receptor and nonreceptor protein tyrosine phosphatases in the nervous system. Cellular and Molecular Life Sciences : Cmls. 60: 2465-82. PMID 14625689 DOI: 10.1007/s00018-003-3123-7  0.362
2003 Blitzer R, Lombroso PJ. Genetics of childhood disorders: LIII. Learning and memory, part 6: induction of long-term potentiation. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 998-1001. PMID 12874504 DOI: 10.1097/01.CHI.0000046894.27264.9D  0.336
2003 Paul S, Nairn AC, Wang P, Lombroso PJ. NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nature Neuroscience. 6: 34-42. PMID 12483215 DOI: 10.1038/nn989  0.559
2002 Nguyen TH, Liu J, Lombroso PJ. Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420. The Journal of Biological Chemistry. 277: 24274-9. PMID 11983687 DOI: 10.1074/Jbc.M111683200  0.358
2002 Pelkey KA, Askalan R, Paul S, Kalia LV, Nguyen TH, Pitcher GM, Salter MW, Lombroso PJ. Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation. Neuron. 34: 127-38. PMID 11931747 DOI: 10.1016/S0896-6273(02)00633-5  0.399
2001 Lombroso PJ, Mercadante MT. Genetics of childhood disorders: XXX. Autoimmune disorders, part 3: myasthenia gravis and Rasmussen's encephalitis. Journal of the American Academy of Child and Adolescent Psychiatry. 40: 1115-7. PMID 11556637 DOI: 10.1097/00004583-200109000-00022  0.334
2001 Naegele JR, Lombroso PJ. Genetics of central nervous system developmental disorders. Child and Adolescent Psychiatric Clinics of North America. 10: 225-39. PMID 11351796 DOI: 10.1016/S1056-4993(18)30055-5  0.588
2000 Paul S, Snyder GL, Yokakura H, Picciotto MR, Nairn AC, Lombroso PJ. The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5630-8. PMID 10908600 DOI: 10.1523/Jneurosci.20-15-05630.2000  0.678
1998 Hockfield S, Lombroso PJ. Development of the cerebral cortex: IX. Cortical development and experience: I. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 992-3. PMID 9735620 DOI: 10.1097/00004583-199809000-00021  0.336
1998 Naegele J, Lombroso PJ. Development of the cerebral cortex: VIII. Apoptosis: neuronal Hari-Kari. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 890-2. PMID 9695453 DOI: 10.1097/00004583-199808000-00021  0.578
1998 Leckman JF, Lombroso PJ. Development of the cerebral cortex: IV. Transcription factors. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 451-2. PMID 9549968 DOI: 10.1097/00004583-199804000-00025  0.326
1996 Bult A, Zhao F, Dirkx R, Sharma E, Lukacsi E, Solimena M, Naegele JR, Lombroso PJ. STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7821-31. PMID 8987810 DOI: 10.1523/Jneurosci.16-24-07821.1996  0.63
1996 Raghunathan A, Matthews GA, Lombroso PJ, Naegele JR. Transient compartmental expression of a family of protein tyrosine phosphatases in the developing striatum. Brain Research. Developmental Brain Research. 91: 190-9. PMID 8852369 DOI: 10.1016/0165-3806(95)00176-X  0.637
1995 Boulanger LM, Lombroso PJ, Raghunathan A, During MJ, Wahle P, Naegele JR. Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1532-44. PMID 7869116 DOI: 10.1523/Jneurosci.15-02-01532.1995  0.614
1995 Sharma E, Lombroso PJ. A neuronal protein tyrosine phosphatase induced by nerve growth factor. The Journal of Biological Chemistry. 270: 49-53. PMID 7814416 DOI: 10.1074/jbc.270.1.49  0.343
1995 Sharma E, Zhao F, Bult A, Lombroso PJ. Identification of two alternatively spliced transcripts of STEP: a subfamily of brain-enriched protein tyrosine phosphatases. Brain Research. Molecular Brain Research. 32: 87-93. PMID 7494467 DOI: 10.1016/0169-328X(95)00066-2  0.375
1994 Naegele JR, Lombroso PJ. Protein tyrosine phosphatases in the nervous system. Critical Reviews in Neurobiology. 9: 105-14. PMID 8828006  0.617
1993 Lombroso PJ, Naegele JR, Sharma E, Lerner M. A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3064-74. PMID 8331384 DOI: 10.1523/Jneurosci.13-07-03064.1993  0.643
1991 Lombroso PJ, Murdoch G, Lerner M. Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum. Proceedings of the National Academy of Sciences of the United States of America. 88: 7242-6. PMID 1714595 DOI: 10.1073/Pnas.88.16.7242  0.338
Low-probability matches (unlikely to be authored by this person)
1998 Brodsky M, Lombroso PJ. Molecular mechanisms of developmental disorders. Development and Psychopathology. 10: 1-20. PMID 9524805 DOI: 10.1017/S0954579498001503  0.299
2002 Murphy T, Goodman W, Lombroso PJ. Genetics of Childhood Disorders: XXXIV. Autoimmune Disorders, Part 7: D8/ 17 Reactivity as an Immunological Marker of Susceptibility to Neuropsychiatric Disorders Journal of the American Academy of Child and Adolescent Psychiatry. 41: 98-100. PMID 11800215 DOI: 10.1097/00004583-200201000-00018  0.298
1999 Nguyen TH, Paul S, Xu Y, Gurd JW, Lombroso PJ. Calcium-dependent cleavage of striatal enriched tyrosine phosphatase (STEP). Journal of Neurochemistry. 73: 1995-2001. PMID 10537058  0.293
2008 Lombroso PJ, Scahill L. Tourette syndrome and obsessive-compulsive disorder. Brain & Development. 30: 231-7. PMID 17937978 DOI: 10.1016/J.Braindev.2007.09.001  0.292
2021 Chatterjee M, Kwon J, Benedict J, Kamceva M, Kurup P, Lombroso PJ. STEP inhibition prevents Aβ-mediated damage in dendritic complexity and spine density in Alzheimer's disease. Experimental Brain Research. PMID 33420799 DOI: 10.1007/s00221-020-06028-x  0.291
2001 Swedo SE, Lombroso PJ. Genetics of childhood disorders: XXXIII. Autoimmunity, part 6: poststreptococcal autoimmunity. Journal of the American Academy of Child and Adolescent Psychiatry. 40: 1479-1482. PMID 11765296 DOI: 10.1097/00004583-200112000-00021  0.29
2003 Sweatt JD, Weeber EJ, Lombroso PJ. Genetics of childhood disorders: LI. Learning and memory, Part 4: Human cognitive disorders and the ras/ERK/CREB pathway. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 741-4. PMID 12921483 DOI: 10.1097/01.CHI.0000046859.56865.A8  0.288
2007 Swain JE, Scahill L, Lombroso PJ, King RA, Leckman JF. Tourette syndrome and tic disorders: a decade of progress. Journal of the American Academy of Child and Adolescent Psychiatry. 46: 947-68. PMID 17667475 DOI: 10.1097/Chi.0B013E318068Fbcc  0.288
2008 Lombroso PJ, Ogren MP. Fragile X syndrome: keys to the molecular genetics of synaptic plasticity. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 736-9. PMID 18574398 DOI: 10.1097/CHI.0b013e3181739619  0.287
2011 Fitzpatrick CJ, Lombroso PJ. The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition. Frontiers in Neuroanatomy. 5: 47. PMID 21863137 DOI: 10.3389/fnana.2011.00047  0.286
2005 Singer HS, Mink JW, Loiselle CR, Burke KA, Ruchkina I, Morshed S, Parveen S, Leckman JF, Hallett JJ, Lombroso PJ. Microinfusion of antineuronal antibodies into rodent striatum: failure to differentiate between elevated and low titers. Journal of Neuroimmunology. 163: 8-14. PMID 15885303 DOI: 10.1016/J.Jneuroim.2005.02.018  0.284
2000 State MW, Lombroso PJ, Pauls DL, Leckman JF. The genetics of childhood psychiatric disorders: a decade of progress. Journal of the American Academy of Child and Adolescent Psychiatry. 39: 946-62. PMID 10939224 DOI: 10.1097/00004583-200008000-00006  0.282
2002 Karasawa T, Yokokura H, Kitajewski J, Lombroso PJ. Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling. The Journal of Biological Chemistry. 277: 37479-86. PMID 12138115 DOI: 10.1074/Jbc.M205658200  0.282
2000 Lombroso PJ. Genetics of childhood disorders: XVI. Angelman syndrome: a failure to process. Journal of the American Academy of Child and Adolescent Psychiatry. 39: 931-3. PMID 10892237 DOI: 10.1097/00004583-200007000-00024  0.281
2002 Lombroso PJ, Mercadante MT. The current "next step" in neuropsychiatric disorders studies Revista Brasileira De Psiquiatria. 24: 111-112. DOI: 10.1590/S1516-44462002000300003  0.28
1998 Marques-Dias MJ, Mercadante MT, Tucker D, Lombroso P. Sydenham's chorea. The Psychiatric Clinics of North America. 20: 809-20. PMID 9443351 DOI: 10.1016/S0193-953X(05)70346-4  0.278
2000 Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, King R, Cohen DJ, Gore JC, Lombroso P. Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention- deficit/hyperactivity disorders Archives of General Psychiatry. 57: 364-372. PMID 10768698 DOI: 10.1001/Archpsyc.57.4.364  0.278
1994 Lombroso PJ, Pauls DL, Leckman JF. Genetic mechanisms in childhood psychiatric disorders. Journal of the American Academy of Child and Adolescent Psychiatry. 33: 921-38. PMID 7525534 DOI: 10.1097/00004583-199409000-00001  0.277
1996 Tucker DM, Leckman JF, Scahill L, Wilf GE, LaCamera R, Cardona L, Cohen P, Heidmann S, Goldstein J, Judge J, Snyder E, Bult A, Peterson BS, King R, Lombroso P. A putative poststreptococcal case of OCD with chronic tic disorder, not otherwise specified. Journal of the American Academy of Child and Adolescent Psychiatry. 35: 1684-91. PMID 8973076 DOI: 10.1097/00004583-199612000-00022  0.273
2002 Lombroso PJ. Genetics of childhood disorders: XXXVII. News flash: a gene for expressive language. Journal of the American Academy of Child and Adolescent Psychiatry. 41: 482-5. PMID 11931607 DOI: 10.1097/00004583-200204000-00023  0.273
2005 Leckman JF, Katsovich L, Kawikova I, Lin H, Zhang H, Krönig H, Morshed S, Parveen S, Grantz H, Lombroso PJ, King RA. Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette's syndrome. Biological Psychiatry. 57: 667-73. PMID 15780855 DOI: 10.1016/J.Biopsych.2004.12.004  0.272
2008 Ogren MP, Lombroso PJ. Epigenetics: behavioral influences on gene function, part I. Maternal behavior permanently affects adult behavior in offspring. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 240-4. PMID 18512291 DOI: 10.1097/CHI.0b013e3181635e13  0.272
2009 Lombroso P, Ogren M. Learning and memory, part II: molecular mechanisms of synaptic plasticity. Journal of the American Academy of Child and Adolescent Psychiatry. 48: 5-9. PMID 19096295 DOI: 10.1097/CHI.0b013e318190c4b3  0.268
1999 Greally JM, Lombroso PJ. Genetics of childhood disorders: VIII. Making sense out of nonsense. Journal of the American Academy of Child and Adolescent Psychiatry. 38: 1458-61. PMID 10560234 DOI: 10.1097/00004583-199911000-00022  0.262
2008 Ogren MP, Lombroso PJ. Epigenetics: behavioral influences on gene function, Part II: Molecular mechanisms. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 374-8. PMID 18356705 DOI: 10.1097/CHI.0b013e318165f163  0.262
2001 Morshed S, Mercadante MT, Lombroso PJ. Genetics of childhood disorders: XXVIII. Autoimmunity, part I. Journal of the American Academy of Child and Adolescent Psychiatry. 40: 855-8. PMID 11437025 DOI: 10.1097/00004583-200107000-00021  0.259
2002 Lord C, Volkmar F, Lombroso P. Genetics of Childhood Disorders: XLII. Autism, Part 1: Diagnosis and Assessment in Autistic Spectrum Disorders Journal of the American Academy of Child and Adolescent Psychiatry. 41: 1134-1136. PMID 12218436 DOI: 10.1097/00004583-200209000-00015  0.258
1995 Lombroso PJ, Scahill L, King RA, Lynch KA, Chappell PB, Peterson BS, McDougle CJ, Leckman JF. Risperidone treatment of children and adolescents with chronic tic disorders: a preliminary report. Journal of the American Academy of Child and Adolescent Psychiatry. 34: 1147-52. PMID 7559308 DOI: 10.1097/00004583-199509000-00011  0.257
2001 Gothelf D, Lombroso PJ. Genetics of childhood disorders: XXV. Velocardiofacial syndrome. Journal of the American Academy of Child and Adolescent Psychiatry. 40: 489-91. PMID 11314577 DOI: 10.1097/00004583-200104000-00021  0.256
2003 Lombroso PJ. Genetics of childhood disorders: XLVIII. Learning and memory, Part 1: Fragile X syndrome update. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 372-5. PMID 12595792 DOI: 10.1097/00004583-200303000-00019  0.256
2000 Mercadante MT, Busatto GF, Lombroso PJ, Prado L, Rosário-Campos MC, do Valle R, Marques-Dias MJ, Kiss MH, Leckman JF, Miguel EC. The psychiatric symptoms of rheumatic fever. The American Journal of Psychiatry. 157: 2036-8. PMID 11097972 DOI: 10.1176/Appi.Ajp.157.12.2036  0.256
2012 Lebowitz ER, Motlagh MG, Katsovich L, King RA, Lombroso PJ, Grantz H, Lin H, Bentley MJ, Gilbert DL, Singer HS, Coffey BJ, Kurlan RM, Leckman JF. Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder. European Child & Adolescent Psychiatry. 21: 451-7. PMID 22543961 DOI: 10.1007/S00787-012-0278-5  0.255
1999 Sparks R, Lombroso PJ, Gruen JR. Genetics of childhood disorders: VII. Cloning genes of interest. Journal of the American Academy of Child and Adolescent Psychiatry. 38: 1316-9. PMID 10517067 DOI: 10.1097/00004583-199910000-00023  0.255
2016 Hsieh LS, Wen JH, Miyares L, Lombroso PJ, Bordey A. Outbred CD1 mice are as suitable as inbred C57BL/6J mice in performing social tasks. Neuroscience Letters. PMID 27871995 DOI: 10.1016/J.Neulet.2016.11.035  0.255
2003 Veenstra-Vanderweele J, Cook E, Lombroso PJ. Genetics of childhood disorders: XLVI. Autism, part 5: genetics of autism. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 116-8. PMID 12500084 DOI: 10.1097/00004583-200301000-00018  0.252
2000 Todd RD, Lombroso PJ. Genetics of childhood disorders: XXI. ADHD, part 5: A behavioral genetic perspective Journal of the American Academy of Child and Adolescent Psychiatry. 39: 1571-1573. PMID 11128337 DOI: 10.1097/00004583-200012000-00023  0.252
2000 Lombroso PJ. Genetics of childhood disorders: XIV. A gene for Rett syndrome: news flash. Journal of the American Academy of Child and Adolescent Psychiatry. 39: 671-4. PMID 10802987 DOI: 10.1097/00004583-200005000-00023  0.252
2001 Osborne L, Pober B, Lombroso PJ. Genetics of childhood disorders: XXVII. Genes and cognition in Williams syndrome Journal of the American Academy of Child and Adolescent Psychiatry. 40: 732-735. PMID 11392353 DOI: 10.1097/00004583-200106000-00021  0.25
2005 Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder. The American Journal of Psychiatry. 162: 1125-32. PMID 15930061 DOI: 10.1176/Appi.Ajp.162.6.1125  0.246
1999 Kohn Y, Lombroso PJ. Genetics of childhood disorders: V. Nonparametric methods of genetic analysis. Journal of the American Academy of Child and Adolescent Psychiatry. 38: 1054-6. PMID 10434500 DOI: 10.1097/00004583-199908000-00024  0.246
2002 Taylor JR, Morshed SA, Parveen S, Mercadante MT, Scahill L, Peterson BS, King RA, Leckman JF, Lombroso PJ. An animal model of Tourette's syndrome. The American Journal of Psychiatry. 159: 657-60. PMID 11925307 DOI: 10.1176/Appi.Ajp.159.4.657  0.245
2001 Mercadante MT, Hounie AG, Diniz JB, Miguel EC, Lombroso PJ. The Basal Ganglia and Immune-Based Neuropsychiatric Disorders Psychiatric Annals. 31: 534-540. DOI: 10.3928/0048-5713-20010901-05  0.244
2003 Sukhodolsky DG, Scahill L, Zhang H, Peterson BS, King RA, Lombroso PJ, Katsovich L, Findley D, Leckman JF. Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 98-105. PMID 12500082 DOI: 10.1097/00004583-200301000-00016  0.243
1998 Lombroso PJ, Sapolsky R. Development of the cerebral cortex: XII. Stress and brain development: I. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 1337-9. PMID 9847508 DOI: 10.1097/00004583-199812000-00019  0.24
1991 King RA, Riddle MA, Chappell PB, Hardin MT, Anderson GM, Lombroso P, Scahill L. Emergence of self-destructive phenomena in children and adolescents during fluoxetine treatment Journal of the American Academy of Child and Adolescent Psychiatry. 30: 179-186. PMID 2016219 DOI: 10.1097/00004583-199103000-00003  0.24
1998 Hockfield S, Lombroso PJ. Development of the cerebral cortex: X. Cortical development and experience: II. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 1103-5. PMID 9785723 DOI: 10.1097/00004583-199810000-00022  0.24
1991 Lombroso PJ, Mack G, Scahill L, King RA, Leckman JF. Exacerbation of Gilles de la Tourette's syndrome associated with thermal stress: a family study. Neurology. 41: 1984-7. PMID 1745360 DOI: 10.1212/Wnl.41.12.1984  0.239
2003 Findley DB, Leckman JF, Katsovich L, Lin H, Zhang H, Grantz H, Otka J, Lombroso PJ, King RA. Development of the Yale Children's Global Stress Index (YCGSI) and its application in children and adolescents ith Tourette's syndrome and obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 450-7. PMID 12649632 DOI: 10.1097/01.Chi.0000046816.95464.Ef  0.238
2001 Morshed SA, Parveen S, Leckman JF, Mercadante MT, Bittencourt Kiss MH, Miguel EC, Arman A, Yazgan Y, Fujii T, Paul S, Peterson BS, Zhang H, King RA, Scahill L, Lombroso PJ. Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette's syndrome, Sydenham's chorea, and autoimmune disorders. Biological Psychiatry. 50: 566-77. PMID 11690591 DOI: 10.1016/S0006-3223(01)01096-4  0.235
1999 Lombroso PJ, Plomin R. Genetics of childhood disorders: III. Genetics and intelligence. Journal of the American Academy of Child and Adolescent Psychiatry. 38: 786-788. DOI: 10.1097/00004583-199906000-00030  0.235
2004 Luo F, Leckman JF, Katsovich L, Findley D, Grantz H, Tucker DM, Lombroso PJ, King RA, Bessen DE. Prospective longitudinal study of children with tic disorders and/or obsessive-compulsive disorder: relationship of symptom exacerbations to newly acquired streptococcal infections. Pediatrics. 113: e578-85. PMID 15173540 DOI: 10.1542/peds.113.6.e578  0.235
2011 Leckman JF, King RA, Gilbert DL, Coffey BJ, Singer HS, Dure LS, Grantz H, Katsovich L, Lin H, Lombroso PJ, Kawikova I, Johnson DR, Kurlan RM, Kaplan EL. Streptococcal upper respiratory tract infections and exacerbations of tic and obsessive-compulsive symptoms: a prospective longitudinal study. Journal of the American Academy of Child and Adolescent Psychiatry. 50: 108-118.e3. PMID 21241948 DOI: 10.1016/J.Jaac.2010.10.011  0.234
2002 Lin H, Yeh CB, Peterson BS, Scahill L, Grantz H, Findley DB, Katsovich L, Otka J, Lombroso PJ, King RA, Leckman JF. Assessment of symptom exacerbations in a longitudinal study of children with Tourette's syndrome or obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 41: 1070-7. PMID 12218428 DOI: 10.1097/00004583-200209000-00007  0.233
2001 Scahill L, Lombroso PJ, Mack G, Van Wattum PJ, Zhang H, Vitale A, Leckman JF. Thermal sensitivity in Tourette syndrome: preliminary report. Perceptual and Motor Skills. 92: 419-32. PMID 11361302 DOI: 10.2466/Pms.2001.92.2.419  0.228
1998 Lombroso PJ, Goldowitz D. Drain development, VIII: the reeler mouse. The American Journal of Psychiatry. 155: 1660. PMID 9842772 DOI: 10.1176/Ajp.155.12.1660  0.228
1999 Gurd JW, Bissoon N, Nguyen TH, Lombroso PJ, Rider CC, Beesley PW, Vannucci SJ. Hypoxia-ischemia in perinatal rat brain induces the formation of a low molecular weight isoform of striatal enriched tyrosine phosphatase (STEP). Journal of Neurochemistry. 73: 1990-4. PMID 10537057  0.227
1996 Scahill L, Lombroso PJ, King RA, Peterson BS, Lynch KA, Leckman JF. TICS AND RISPERIDONE Journal of the American Academy of Child & Adolescent Psychiatry. 35: 840. DOI: 10.1097/00004583-199607000-00005  0.227
2010 Lin H, Williams KA, Katsovich L, Findley DB, Grantz H, Lombroso PJ, King RA, Bessen DE, Johnson D, Kaplan EL, Landeros-Weisenberger A, Zhang H, Leckman JF. Streptococcal upper respiratory tract infections and psychosocial stress predict future tic and obsessive-compulsive symptom severity in children and adolescents with Tourette syndrome and obsessive-compulsive disorder. Biological Psychiatry. 67: 684-91. PMID 19833320 DOI: 10.1016/J.Biopsych.2009.08.020  0.227
1999 Ward D, Bray-Ward P, Lombroso PJ. Genetics of childhood disorders: VI. FISH, FISH, and more FISH. Journal of the American Academy of Child and Adolescent Psychiatry. 38: 1200-2. PMID 10504822 DOI: 10.1097/00004583-199909000-00028  0.226
2010 Motlagh MG, Katsovich L, Thompson N, Lin H, Kim YS, Scahill L, Lombroso PJ, King RA, Peterson BS, Leckman JF. Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndrome. European Child & Adolescent Psychiatry. 19: 755-64. PMID 20532931 DOI: 10.1007/S00787-010-0115-7  0.224
1998 Rakic P, Lombroso PJ. Development of the cerebral cortex: I. Forming the cortical structure. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 116-7. PMID 9444908 DOI: 10.1097/00004583-199801000-00026  0.223
2007 Lin H, Katsovich L, Ghebremichael M, Findley DB, Grantz H, Lombroso PJ, King RA, Zhang H, Leckman JF. Psychosocial stress predicts future symptom severities in children and adolescents with Tourette syndrome and/or obsessive-compulsive disorder. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 48: 157-66. PMID 17300554 DOI: 10.1111/J.1469-7610.2006.01687.X  0.222
1998 Lombroso PJ. Development of the cerebral cortex: VI. growth factors: I. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 674-5. PMID 9628090 DOI: 10.1097/00004583-199806000-00020  0.219
2014 McGuire JF, Sukhodolsky DG, Bearss K, Grantz H, Pachler M, Lombroso PJ, Scahill L. Individualized assessments in treatment research: an examination of parent-nominated target problems in the treatment of disruptive behaviors in youth with Tourette syndrome. Child Psychiatry and Human Development. 45: 686-94. PMID 24477478 DOI: 10.1007/S10578-014-0437-7  0.218
1998 Vaccarino F, Lombroso PJ. Development of the cerebral cortex: VII. Growth factors: II. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 789-90. PMID 9666636 DOI: 10.1097/00004583-199807000-00020  0.217
1998 Reiner O, Lombroso PJ. Development of the cerebral cortex: II. Lissencephaly. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 231-2. PMID 9473922 DOI: 10.1097/00004583-199802000-00018  0.216
1998 Lombroso PJ. Development of the cerebral cortex: III. The reeler mutation. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 333-4. PMID 9519640 DOI: 10.1097/00004583-199803000-00020  0.214
1997 Bult A, Zhao F, Dirkx R, Raghunathan A, Solimena M, Lombroso PJ. STEP: a family of brain-enriched PTPs. Alternative splicing produces transmembrane, cytosolic and truncated isoforms. European Journal of Cell Biology. 72: 337-44. PMID 9127733  0.203
1998 Leckman JF, Lombroso PJ. Introduction: Why Should a Child and Adolescent Psychiatrist Care About Genetics and Neuroscience? Journal of the American Academy of Child & Adolescent Psychiatry. 37: 115. DOI: 10.1097/00004583-199801000-00025  0.202
2000 Lombroso PJ. FRAGILE X SYNDROME Journal of the American Academy of Child & Adolescent Psychiatry. 39: 398-399. DOI: 10.1097/00004583-200004000-00003  0.199
2004 Lee TS, Lee TD, Lombroso PJ, King RA. Atomoxetine and tics in ADHD. Journal of the American Academy of Child and Adolescent Psychiatry. 43: 1068-9. PMID 15322408 DOI: 10.1097/01.chi.0000132833.12842.4e  0.192
2014 Darcq E, Hamida SB, Wu S, Phamluong K, Kharazia V, Xu J, Lombroso P, Ron D. Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption. Journal of Neurochemistry. 129: 1024-34. PMID 24588427 DOI: 10.1111/Jnc.12701  0.191
2008 Ogren MP, Lombroso PJ. Back to basics Journal of the American Academy of Child and Adolescent Psychiatry. 47: 238. DOI: 10.1097/CHI.0b013e318161987c  0.187
1994 Fricker RA, Torres EM, Lombroso PJ, Dunnett SB. The localization of an antibody to STEP in embryonic striatal tissue grafts. Neuroreport. 5: 2638-40. PMID 7696621  0.14
1995 Li X, Luna J, Lombroso PJ, Francke U. Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci. Genomics. 28: 442-9. PMID 7490079 DOI: 10.1006/Geno.1995.1173  0.137
2021 Lambert LJ, Grotegut S, Celeridad M, Gosalia P, Backer LJ, Bobkov AA, Salaniwal S, Chung TD, Zeng FY, Pass I, Lombroso PJ, Cosford ND, Tautz L. Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP). International Journal of Molecular Sciences. 22. PMID 33922601 DOI: 10.3390/ijms22094417  0.135
2022 Dedek A, Xu J, Lorenzo LÉ, Godin AG, Kandegedara CM, Glavina G, Landrigan JA, Lombroso PJ, De Koninck Y, Tsai EC, Hildebrand ME. Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain. Brain : a Journal of Neurology. PMID 35323848 DOI: 10.1093/brain/awab408  0.129
2001 Stocks M, Lombroso PJ. Genetics of childhood disorders: XXIX. Autoimmune disorders, part 2: Molecular mimicry Journal of the American Academy of Child and Adolescent Psychiatry. 40: 977-980. PMID 11501699  0.117
2001 Gainetdinov RR, Caron MG, Lombroso PJ. Genetics of childhood disorders: XXIV. ADHD, part 8: Hyperdopaminergic mice as an animal model of ADHD Journal of the American Academy of Child and Adolescent Psychiatry. 40: 380-382. PMID 11288782  0.113
2001 Bessen DE, Lombroso PJ. Genetics of childhood disorders: XXXII. Autoimmune disorders, part 5: Streptococcal infection and autoimmunity, an epidemiological perspective Journal of the American Academy of Child and Adolescent Psychiatry. 40: 1346-1348. PMID 11699810  0.111
1995 Lombroso PJ, Scahill LD, Chappell PB, Pauls DL, Cohen DJ, Leckman JF. Tourette's syndrome: a multigenerational, neuropsychiatric disorder. Advances in Neurology. 65: 305-18. PMID 7872149  0.111
2003 Sutcliffe JS, Nurmi EL, Lombroso PJ. Genetics of childhood disorders: XLVII. Autism, part 6: duplication and inherited susceptibility of chromosome 15q11-q13 genes in autism. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 253-6. PMID 12544187 DOI: 10.1097/00004583-200302000-00021  0.109
2014 Bloch MH, Lennington JB, Szuhay G, Lombroso PJ. Obsessive-Compulsive Disorder Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 1301-1310. DOI: 10.1016/B978-0-12-410529-4.00106-6  0.103
2000 Eliez S, Reiss AL, Lombroso PJ. Genetics of childhood disorders: XI. Fragile X syndrome Journal of the American Academy of Child and Adolescent Psychiatry. 39: 264. PMID 10673840 DOI: 10.1097/00004583-200002000-00029  0.103
2001 Lombroso PJ, Quist JF, Kennedy JL. Genetics of childhood disorders: XXIII. ADHD, Part 7: The serotonin system Journal of the American Academy of Child and Adolescent Psychiatry. 40: 253-256. PMID 11211376 DOI: 10.1097/00004583-200102000-00022  0.099
2000 Everman DB, Cassidy SB, Lombroso PJ. Genetics of childhood disorders: XII. Genomic imprinting: Breaking the rules Journal of the American Academy of Child and Adolescent Psychiatry. 39: 386-389. PMID 10714060  0.097
2000 Biederman J, Spencer TJ, Lombroso PJ. Genetics of childhood disorders: XIX. ADHD, Part 3: Is ADHD a noradrenergic disorder? Journal of the American Academy of Child and Adolescent Psychiatry. 39: 1330-1333. PMID 11026191  0.093
2008 Moura PJ, Lombroso PJ, Mercadante MT. Autism Advances in Biological Psychiatry. 24: 21-38. DOI: 10.1159/000118514  0.076
2004 Gothelf D, Brand-Gothelf A, Apter A, Sever Y, Bodinger L, Lombroso PJ, Tyano S, Cohen DJ. Schizophrenia in adolescent twins: a case study. The Israel Journal of Psychiatry and Related Sciences. 41: 54-60. PMID 15160656  0.076
1998 Kirn J, Lombroso PJ. Development of the cerebral cortex: XI. Sexual dimorphism in the brain. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 1228-30. PMID 9808936  0.075
2001 Bessen DE, Lombroso PJ. Group A streptococcal infections and their potential role in neuropsychiatric disease. Advances in Neurology. 85: 295-305. PMID 11530436  0.067
2005 Burke K, Lombroso PJ. Animal models of tourette syndrome Movement Disorders. 441-448. DOI: 10.1016/B978-012088382-0/50040-2  0.054
1998 Sabry MA, Farah SA, Farag TI, Lombroso PJ. Lissencephaly revisited [1] (multiple letters) Journal of the American Academy of Child and Adolescent Psychiatry. 37: 899.  0.028
1987 Lombroso P, Eng L. Computerizing a department of psychiatry Administration in Mental Health. 15: 102-109. DOI: 10.1007/BF00819350  0.01
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