Selwyn S. Jayakar, Ph.D. - Publications

Institution:
The University of Toledo
Area:
nicotinic receptors, neuropeptides

21/38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. PMID 32541553 DOI: 10.1097/Aln.0000000000003403  0.376
2020 Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry. PMID 32540960 DOI: 10.1074/Jbc.Ra120.013452  0.368
2018 Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824. PMID 30544077 DOI: 10.1016/J.Ejmech.2018.11.019  0.391
2018 McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE. Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology. PMID 30052529 DOI: 10.1097/Aln.0000000000002356  0.35
2017 Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE. Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology. PMID 28857763 DOI: 10.1097/Aln.0000000000001840  0.336
2017 Jayakar SS, Ang G, Chiara DC, Hamouda AK. Photoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding Sites. Methods in Molecular Biology (Clifton, N.J.). 1598: 157-197. PMID 28508361 DOI: 10.1007/978-1-4939-6952-4_7  0.307
2016 Jayakar SS, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Identifying GABA-A Receptor Modulators that Bind to Intersubunit Sites in the GABA-A Receptor Transmembrane Domain Biophysical Journal. 110: 454a-455a. DOI: 10.1016/J.Bpj.2015.11.2437  0.366
2015 Mohamed TS, Jayakar SS, Hamouda AK. Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation. Frontiers in Molecular Neuroscience. 8: 71. PMID 26635524 DOI: 10.3389/Fnmol.2015.00071  0.405
2015 Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry. PMID 26229099 DOI: 10.1074/Jbc.M115.672006  0.367
2014 Jayakar SS, Pugh PC, Dale Z, Starr ER, Cole S, Margiotta JF. PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting. Molecular and Cellular Neurosciences. 63: 1-12. PMID 25168001 DOI: 10.1016/J.Mcn.2014.08.007  0.681
2014 Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68. PMID 25086038 DOI: 10.1074/Jbc.M114.581728  0.346
2014 Hamouda AK, Jayakar SS, Chiara DC, Cohen JB. Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites! Journal of Molecular Neuroscience : Mn. 53: 480-6. PMID 24158732 DOI: 10.1007/S12031-013-0150-1  0.372
2013 Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor. The Journal of Biological Chemistry. 288: 19343-57. PMID 23677991 DOI: 10.1074/Jbc.M113.479725  0.384
2013 Jayakar SS, Dailey WP, Eckenhoff RG, Cohen JB. Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog. The Journal of Biological Chemistry. 288: 6178-89. PMID 23300078 DOI: 10.1074/Jbc.M112.435909  0.379
2013 Jayakar SS, Zhou X, Dostalova Z, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Identifying the Propofol Binding Site(S) in Heterologously Expressed Human Alpha1 Beta3 Gaba-A Receptors using a Photoreactive Propofol Analog Biophysical Journal. 104: 637a. DOI: 10.1016/J.Bpj.2012.11.3519  0.336
2012 Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 51: 836-47. PMID 22243422 DOI: 10.1021/Bi201772M  0.324
2011 Jayakar SS, Margiotta JF. Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on autonomic neurons. Molecular Pharmacology. 80: 97-109. PMID 21502378 DOI: 10.1124/Mol.111.071308  0.738
2011 Jayakar∗ SS, Dostalova Z, Chiara DC, Zhou X, Liu A, Miller KW, Cohen JB. Identifying an Etomidate Binding Site in Heterologously Expressed Human Alpha1/Beta3 GABAA Receptors (GABAAR) Using Photoactive Etomidate Analogs Biophysical Journal. 100: 271a. DOI: 10.1016/J.Bpj.2010.12.1689  0.346
2010 Pugh PC, Jayakar SS, Margiotta JF. PACAP/PAC1R signaling modulates acetylcholine release at neuronal nicotinic synapses. Molecular and Cellular Neurosciences. 43: 244-57. PMID 19958833 DOI: 10.1016/J.Mcn.2009.11.007  0.676
2006 Pugh PC, Zhou X, Jayakar SS, Margiotta JF. Depolarization promotes survival of ciliary ganglion neurons by BDNF-dependent and -independent mechanisms. Developmental Biology. 291: 182-91. PMID 16426601 DOI: 10.1016/J.Ydbio.2005.12.008  0.646
2004 Jayakar SS, Dikshit M. AMPA receptor regulation mechanisms: future target for safer neuroprotective drugs. The International Journal of Neuroscience. 114: 695-734. PMID 15204061 DOI: 10.1080/00207450490430453  0.452
Low-probability matches (unlikely to be authored by this person)
2019 Jayakar SS, Zhou X, Wu B, Miller KW, Bruzik KS, Cohen JB. Pharmacological Selectivity of a Steroid Binding Site at the Beta+-Alpha− Interface of Alpha1 Beta3 Gaba-A Receptors Biophysical Journal. 116: 392a. DOI: 10.1016/J.Bpj.2018.11.2122  0.293
2019 Chiara DC, Wu B, Zhou X, Jayakar SS, Titterton K, Forman SA, Miller KW, Bruzik KS, Cohen JB. Identification of a High-Affinity Neurosteroid Binding Site in Human Alpha1Beta3 GabaAR using a Photoreactive Thdoc Analog Biophysical Journal. 116: 392a. DOI: 10.1016/J.Bpj.2018.11.2123  0.278
2020 McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam. Anesthesiology. 133: 583-594. PMID 33370831 DOI: 10.1097/ALN.0000000000003403  0.248
2023 Deng T, Jovanovic VM, Tristan CA, Weber C, Chu PH, Inman J, Ryu S, Jethmalani Y, Ferreira de Sousa J, Ormanoglu P, Twumasi P, Sen C, Shim J, Jayakar S, Bear Zhang HX, et al. Scalable generation of sensory neurons from human pluripotent stem cells. Stem Cell Reports. 18: 1030-1047. PMID 37044067 DOI: 10.1016/j.stemcr.2023.03.006  0.24
2022 Zhang HB, Heckman L, Niday Z, Jo S, Fujita A, Shim J, Pandey R, Al Jandal H, Jayakar S, Barrett LB, Smith J, Woolf CJ, Bean BP. Cannabidiol activates neuronal Kv7 channels. Elife. 11. PMID 35179483 DOI: 10.7554/eLife.73246  0.205
2019 Jayakar SS, Zhou X, Chiara DC, Jarava-Barrera C, Savechenkov PY, Bruzik KS, Tortosa M, Miller KW, Cohen JB. Identifying drugs that bind selectively to intersubunit general anesthetic sites in the α1β3γ2 GABAR transmembrane domain. Molecular Pharmacology. PMID 30952799 DOI: 10.1124/Mol.118.114975  0.18
2023 Xie L, Yin Y, Jayakar S, Kawaguchi R, Wang Q, Peterson S, Shi C, Turnes BL, Zhang Z, Oses-Prieto J, Li J, Burlingame A, Woolf CJ, Geschwind D, Rasband M, et al. The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC-derived sensory neurons. Science Translational Medicine. 15: eadg6241. PMID 37556559 DOI: 10.1126/scitranslmed.adg6241  0.142
2023 Salimando GJ, Tremblay S, Kimmey BA, Li J, Rogers SA, Wojick JA, McCall NM, Wooldridge LM, Rodrigues A, Borner T, Gardiner KL, Jayakar SS, Singeç I, Woolf CJ, Hayes MR, et al. Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types. Nature Communications. 14: 5632. PMID 37704594 DOI: 10.1038/s41467-023-41407-2  0.13
2022 Kotoda M, Matsuoka T, Wada K, Jayakar S, Ino H, Kawago K, Kumakura Y. Amiodarone Provides Long-Lasting Local Anesthesia and Analgesia in Open-State Mouse Nociceptors. Frontiers in Pharmacology. 13: 872477. PMID 35370742 DOI: 10.3389/fphar.2022.872477  0.104
2023 Hwang CD, Hoftiezer YAJ, Raasveld FV, Gomez-Eslava B, van der Heijden EPA, Jayakar S, Black BJ, Johnston BR, Wainger BJ, Renthal W, Woolf CJ, Eberlin KR. Biology and pathophysiology of symptomatic neuromas. Pain. PMID 37851396 DOI: 10.1097/j.pain.0000000000003055  0.084
2013 Hinkle L, Brouillette A, Jayakar S, Gathings L, Lezcano M, Kalita J. Design and evaluation of soft keyboards for brahmic scripts Acm Transactions On Asian Language Information Processing. 12. DOI: 10.1145/2461316.2461318  0.063
2013 Jayakar SS, Singhal RS. Kinetic modeling and scale up of lipoic acid (LA) production from Saccharomyces cerevisiae in a stirred tank bioreactor. Bioprocess and Biosystems Engineering. 36: 1063-70. PMID 23178984 DOI: 10.1007/s00449-012-0859-1  0.04
2016 Jayakar S, Strichartz RS. Average number of lattice points in a disk Communications On Pure and Applied Analysis. 15: 1-8. DOI: 10.3934/Cpaa.2016.15.1  0.037
1978 Ugazio AG, Lanzavecchia A, Jayakar S, Plebani A, Duse M, Burgio GR. Immunodeficiency in Down's syndrome. Titres of 'natural' antibodies to E. coli and rabbit erythrocytes at different ages Acta Paediatrica Scandinavica. 67: 705-708. PMID 152559  0.033
2021 Jayakar S, Shim J, Jo S, Bean BP, Singeç I, Woolf CJ. Developing nociceptor-selective treatments for acute and chronic pain. Science Translational Medicine. 13: eabj9837. PMID 34757806 DOI: 10.1126/scitranslmed.abj9837  0.031
1980 Burgio GR, Lanzavecchia A, Plebani A, Jayakar S, Ugazio AG. Ontogeny of secretory immunity: Levels of secretory IgA and natural antibodies in saliva Pediatric Research. 14: 1111-1114. PMID 7008011  0.016
1982 Piazza A, Olivetti E, Carbonara AO, Bargagna M, Pecori F, Benciolini P, Cortivo P, Breda F, Domenici R, Jayakar S. The distribution of some genetic polymorphisms in Italy | La distribuzione di alcuni polimorfismi genetici in Italia. Ricerca in Clinica E in Laboratorio. 1-108. PMID 6818669  0.01
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