Michael R. Braden, Ph.D. - Related publications

Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
Dopamine and Serotonin Agonists
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Bubak AN, Watt MJ, Yaeger JDW, Renner KJ, Swallow JG. The stalk-eyed fly as a model for aggression - is there a conserved role for 5-HT between vertebrates and invertebrates? The Journal of Experimental Biology. 223. PMID 31896721 DOI: 10.1242/jeb.132159   
2020 Yang J, Huang Q, Liu H, Zhou X, Huang Z, Peng Q, Liu C. 4-Nonylphenol and 4-tert-octylphenol induce anxiety-related behaviors through alternation of 5-HT receptors and transporters in the prefrontal cortex. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 108701. PMID 31911191 DOI: 10.1016/j.cbpc.2020.108701   
2020 Cruz-Corchado J, Ooi FK, Das S, Prahlad V. Global Transcriptome Changes That Accompany Alterations in Serotonin Levels in . G3 (Bethesda, Md.). PMID 31996358 DOI: 10.1534/g3.120.401088   
2020 Wang W, Zheng L, Li W, Zhu C, Peng W, Han B, Fu W. Design, Synthesis and Structure-activity Relationship Studies of Novel Indolyalkylpiperazine Derivatives as Selective 5-HT Receptor Agonists. Journal of Chemical Information and Modeling. PMID 31913624 DOI: 10.1021/acs.jcim.9b00926   
2020 Guros NB, Balijepalli A, Klauda JB. Microsecond-timescale simulations suggest 5-HT-mediated preactivation of the 5-HT serotonin receptor. Proceedings of the National Academy of Sciences of the United States of America. 117: 405-414. PMID 31871207 DOI: 10.1073/pnas.1908848117   
2020 Abela AR, Ji XD, Li Z, Lê AD, Fletcher PJ. Clozapine reliably increases the motivation for food: parsing the role of the 5-HT and H receptors. Psychopharmacology. PMID 31897573 DOI: 10.1007/s00213-019-05425-7   
2020 Annamalai B, Ragu Varman D, Horton RE, Daws LC, Jayanthi LD, Ramamoorthy S. Histamine Receptors Regulate the Activity, Surface Expression and Phosphorylation of Serotonin Transporters. Acs Chemical Neuroscience. PMID 31916747 DOI: 10.1021/acschemneuro.9b00664   
2020 Li C, Meng F, Garza JC, Liu J, Lei Y, Kirov SA, Guo M, Lu XY. Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons. Molecular Psychiatry. PMID 31980728 DOI: 10.1038/s41380-020-0649-0   
2020 Hussein I, Al Halabi M, Kowash M, Salami A, Ouatik N, Yang YM, Duggal M, Chandwani N, Nazzal H, Albadri S, Roberts A, Al-Jundi S, Nzomiwu C, El Shahawy O, Attaie A, et al. Use of the Hall technique by specialist paediatric dentists: a global perspective. British Dental Journal. 228: 33-38. PMID 31925371 DOI: 10.1038/s41415-019-1100-2   
2020 Abela AR, Browne CJ, Sargin D, Prevot TD, Ji XD, Li Z, Lambe EK, Fletcher PJ. Median raphe serotonin neurons promote anxiety-like behavior via inputs to the dorsal hippocampus. Neuropharmacology. 107985. PMID 32035145 DOI: 10.1016/j.neuropharm.2020.107985   
2020 Cong M, Song J, Chen F, Cao C, Wang S. A surrogate analyte-based LC-MS/MS method for the determination of 5-hydroxytryptamine, kynurenine and tryptophan. Bioanalysis. PMID 32026711 DOI: 10.4155/bio-2019-0267   
2020 Ryu Y, Maekawa T, Yoshino D, Sakitani N, Takashima A, Inoue T, Suzurikawa J, Toyohara J, Tago T, Makuuchi M, Fujita N, Sawada K, Murase S, Watanave M, Hirai H, et al. Mechanical Regulation Underlies Effects of Exercise on Serotonin-Induced Signaling in the Prefrontal Cortex Neurons. Iscience. 23: 100874. PMID 32062453 DOI: 10.1016/j.isci.2020.100874   
2020 Mao Q, Zhang B, Li W, Tian S, Shui W, Ye N. Identification of Novel 1-O-substituted Aporphine Analogues as Potent 5-HT2C Receptor Agonists. Acs Chemical Neuroscience. PMID 31968160 DOI: 10.1021/acschemneuro.9b00563   
2020 Olajide TM, Liu T, Liu H, Weng X. Antioxidant properties of two novel lipophilic derivatives of hydroxytyrosol. Food Chemistry. 315: 126197. PMID 32018079 DOI: 10.1016/j.foodchem.2020.126197   
2020 Zhang SR, Wu JL, Chen H, Luo R, Chen WJ, Tang LJ, Li XW, Yang JM, Gao TM. ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31905370 DOI: 10.1038/s41386-020-0601-7   
2020 Wang H, Gao XY, Rao F, Yang H, Wang ZY, Liu L, Kuang SJ, Wu Q, Deng CY, Xu JS. Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 31980857 DOI: 10.1007/s00210-020-01813-5   
2020 Ananth M, Bartlett EA, DeLorenzo C, Lin X, Kunkel L, Vadhan NP, Perlman G, Godstrey M, Holzmacher D, Ogden RT, Parsey RV, Huang C. Prediction of lithium treatment response in bipolar depression using 5-HTT and 5-HT PET. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32055965 DOI: 10.1007/s00259-020-04681-6   
2020 Lee JA, Levy DA, Patel KG, Brennan E, Oyer SL. Hair transplantation in frontal fibrosing alopecia and lichen planopilaris: A systematic review. The Laryngoscope. PMID 32045028 DOI: 10.1002/lary.28551   
2020 Babin V, Tournier BB, Davis A, Dubost E, Pigrée G, Lohier JF, Reboul V, Cailly T, Bouillon JP, Millet P, Fabis F. Design of iodinated radioligands for SPECT imaging of central human 5-HTR using a ligand lipophilicity efficiency approach. Bioorganic Chemistry. 96: 103582. PMID 31978687 DOI: 10.1016/j.bioorg.2020.103582   
2020 Xia J, Zhang Q, Wang Y, Luan J, Yang J, Cong R, Wang Z, Song N. Association of NE, leptin and 5-HT with electrophysiological parameters in patients with primary premature ejaculation. Andrology. PMID 32068350 DOI: 10.1111/andr.12773   
2020 Pujol CN, Dupuy V, Séveno M, Runtz L, Bockaert J, Marin P, Chaumont-Dubel S. Dynamic interactions of the 5-HT receptor with protein partners control dendritic tree morphogenesis. Science Signaling. 13. PMID 32047117 DOI: 10.1126/scisignal.aax9520   
2020 Arashi H, Sato T, Kobashigawa J, Luikart H, Kobayashi Y, Okada K, Sinha S, Honda Y, Yeung AC, Khush K, Fearon WF. Long-term clinical outcomes with use of an angiotensin-converting enzyme inhibitor early after heart transplantation. American Heart Journal. 222: 30-37. PMID 32007823 DOI: 10.1016/j.ahj.2020.01.003   
2020 Chen J, Xu Y, Fei K, Wang R, He J, Fu L, Shao S, Li K, Zhu K, Zhang W, Wang Z, Yang J. Physiological mechanism underlying the effect of high temperature during anthesis on spikelet-opening of photo-thermo-sensitive genic male sterile rice lines. Scientific Reports. 10: 2210. PMID 32042005 DOI: 10.1038/s41598-020-59183-0   
2020 Pinheiro Sartori D, de Oliveira NF, Valentim JT, da Silva DMA, Serra Vasconcelos A, Maia Oliveira IC, de Castro Chaves R, Cavalcanti Capibaribe VC, de Carvalho AMR, de Oliveira Rebouças M, Macêdo D, Maia Chaves Filho AJ, de França Fonteles MM, Chavez Gutierrez SJ, Barbosa-Filho JM, et al. Involvement of monoaminergic targets in the antidepressant- and anxiolytic-like effects of the synthetic alkamide Riparin IV: elucidation of further mechanisms through pharmacological, neurochemistry and computational approaches. Behavioural Brain Research. 112487. PMID 31987932 DOI: 10.1016/j.bbr.2020.112487   
2020 Perim RR, Fields DP, Mitchell GS. Spinal AMP Kinase Activity Differentially Regulates Phrenic Motor Plasticity. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 31971473 DOI: 10.1152/japplphysiol.00546.2019   
2020 Halberstadt AL, Chatha M, Klein AK, Wallach J, Brandt SD. Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species. Neuropharmacology. 107933. PMID 31917152 DOI: 10.1016/j.neuropharm.2019.107933   
2020 Zhang JG, Huang XY, Ma YB, Chen JJ, Geng CA. UFLC-PDA-MS/MS Profiling of Seven Uncaria Species Integrated with Melatonin/5-Hydroxytryptamine Receptors Agonistic Assay. Natural Products and Bioprospecting. PMID 31933166 DOI: 10.1007/s13659-020-00230-8   
2020 Silva ON, Franco OL, Neves BJ, Morais ÁCB, De Oliveira Neto JR, da Cunha LC, Naves LM, Pedrino GR, Costa EA, Fajemiroye JO. Involvement of the gabaergic, serotonergic and glucocorticoid mechanism in the anxiolytic-like effect of mastoparan-L. Neuropeptides. 102027. PMID 32059939 DOI: 10.1016/j.npep.2020.102027   
2020 Frei JN, Broadhurst RW, Bostock MJ, Solt A, Jones AJY, Gabriel F, Tandale A, Shrestha B, Nietlispach D. Conformational plasticity of ligand-bound and ternary GPCR complexes studied by F NMR of the β-adrenergic receptor. Nature Communications. 11: 669. PMID 32015348 DOI: 10.1038/s41467-020-14526-3   
2020 Iihara H, Shimokawa M, Hayasaki Y, Fujita Y, Abe M, Takenaka M, Yamamoto S, Arai T, Sakurai M, Mori M, Nakamura K, Kado N, Murase S, Shimaoka R, Suzuki A, et al. Efficacy and safety of 5 mg olanzapine combined with aprepitant, granisetron and dexamethasone to prevent carboplatin-induced nausea and vomiting in patients with gynecologic cancer: A multi-institution phase II study. Gynecologic Oncology. PMID 31926638 DOI: 10.1016/j.ygyno.2020.01.004   
2020 Zachmann J, Kritsi E, Tapeinou A, Zoumpoulakis P, Tselios T, Matsoukas MT. A Combined Computational and Structural Approach into Understanding the Role of Peptide Binding and Activation of the Melanocortin Receptor 4. Journal of Chemical Information and Modeling. PMID 31944109 DOI: 10.1021/acs.jcim.9b01196   
2020 Kurz M, Krett AL, Bunemann M. Voltage dependence of prostanoid receptors. Molecular Pharmacology. PMID 32005759 DOI: 10.1124/mol.119.118372   
2020 Brandt L, Jones JD, Martinez S, Manubay JM, Mogali S, Ramey T, Levin FR, Comer SD. Effects of lorcaserin on oxycodone self-administration and subjective responses in participants with opioid use disorder. Drug and Alcohol Dependence. 107859. PMID 31980285 DOI: 10.1016/j.drugalcdep.2020.107859   
2020 Lo CH, Huber EC, Sachs JN. Conformational states of TNFR1 as a molecular switch for receptor function. Protein Science : a Publication of the Protein Society. PMID 31960514 DOI: 10.1002/pro.3829   
2020 Nirogi R, Mohammed AR, Shinde AK, Ravella SR, Bogaraju N, Subramanian R, Mekala VR, Palacharla RC, Muddana N, Thentu JB, Bhyrapuneni G, Abraham R, Jasti V. Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane hydrochloride (SUVN-911): A Novel, Potent, Selective and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression. Journal of Medicinal Chemistry. PMID 32026697 DOI: 10.1021/acs.jmedchem.9b00790   
2020 De Deurwaerdère P, Bharatiya R, Chagraoui A, Di Giovanni G. Constitutive activity of 5-HT receptors: Factual analysis. Neuropharmacology. 107967. PMID 31958408 DOI: 10.1016/j.neuropharm.2020.107967   
2020 Su Z, Wu Y. A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily. Computational and Structural Biotechnology Journal. 18: 258-270. PMID 32021664 DOI: 10.1016/j.csbj.2019.12.016   
2020 Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, et al. Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science (New York, N.Y.). 367: 643-652. PMID 32029621 DOI: 10.1126/science.aaw3242   
2020 Lamichhane R, Liu JJ, White KL, Katritch V, Stevens RC, Wüthrich K, Millar DP. Biased Signaling of the G-Protein-Coupled Receptor βAR Is Governed by Conformational Exchange Kinetics. Structure (London, England : 1993). PMID 31978323 DOI: 10.1016/j.str.2020.01.001   
2020 Zhao S, Guo S, Yang C, Gong Z, Wang Y, Jia Y, Jiang X, Xu L, Shi L, Yu X, Sun J, Zhang Y, Chen X. Cell active and functionally-relevant small-molecule agonists of calcitonin receptor. Bioorganic Chemistry. 96: 103596. PMID 32004895 DOI: 10.1016/j.bioorg.2020.103596   
2020 Fráguas RM, Costa VA, Terra WC, Aguiar AP, Martins SJ, Campos VP, Oliveira DF. Toxicities of 4,5-Dihydroisoxazoles Against Root-Knot Nematodes and in Silico Studies of Their Modes of Action. Journal of Agricultural and Food Chemistry. 68: 523-529. PMID 31908169 DOI: 10.1021/acs.jafc.9b07839   
2020 Fisher R, Hikima A, Morris R, Jackson MJ, Rose S, Varney MA, Depoortere R, Newman-Tancredi A. The selective 5-HT receptor agonist, NLX-112, exerts anti-dyskinetic and anti-parkinsonian-like effects in MPTP-treated marmosets. Neuropharmacology. 107997. PMID 32057799 DOI: 10.1016/j.neuropharm.2020.107997   
2020 Landau AM, Noer O, Alstrup AKO, Audrain H, Wegener G, Gjedde A, Doudet DJ, Winterdahl M. Type of Anaesthetic Influences [C]MDL100,907 Binding to 5HT Receptors in Porcine Brain. Molecular Imaging and Biology. PMID 31993926 DOI: 10.1007/s11307-020-01476-x   
2020 Ma Y, Ding Y, Song X, Ma X, Li X, Zhang N, Song Y, Sun Y, Shen Y, Zhong W, Hu LA, Ma Y, Zhang MY. Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Science Advances. 6: eaax7379. PMID 31998837 DOI: 10.1126/sciadv.aax7379   
2020 Sanchez-Soto M, Verma RK, Willette BKA, Gonye EC, Moore AM, Moritz AE, Boateng CA, Yano H, Free RB, Shi L, Sibley DR. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science Signaling. 13. PMID 32019899 DOI: 10.1126/scisignal.aaw5885   
2020 Nesbit MO, Phillips AG. Tetrahydroprotoberberines: A Novel Source of Pharmacotherapies for Substance Use Disorders? Trends in Pharmacological Sciences. PMID 31987662 DOI: 10.1016/j.tips.2019.12.007   
2020 Shabaan MA, Kamal AM, Faggal SI, Elsahar AE, Mohamed KO. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase. Archiv Der Pharmazie. e1900308. PMID 32031284 DOI: 10.1002/ardp.201900308   
2020 Wang H, Lane K, Lou Z, Parker S, Placke M. Genotoxicity and carcinogenicity risk assessment of prucalopride, a selective 5-hydroxytryptamine 4 receptor agonist. Regulatory Toxicology and Pharmacology : Rtp. 104586. PMID 31972188 DOI: 10.1016/j.yrtph.2020.104586   
2020 Tsai M, Case M, Ardayfio P, Hochstetler H, Wilbraham D. Effects of Lasmiditan on Cardiovascular Parameters and Pharmacokinetics in Healthy Subjects Receiving Oral Doses of Propranolol. Clinical Pharmacology in Drug Development. PMID 31950732 DOI: 10.1002/cpdd.768   
2020 Liang YL, Belousoff MJ, Zhao P, Koole C, Fletcher MM, Truong TT, Julita V, Christopoulos G, Xu HE, Zhang Y, Khoshouei M, Christopoulos A, Danev R, Sexton PM, Wootten D. Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Molecular Cell. PMID 32004469 DOI: 10.1016/j.molcel.2020.01.012