Juan P. Cueva, Ph.D. - Publications

Affiliations: 
Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
Area:
Dopamine and Serotonin Agonists

7/15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Juncosa JI, Hansen M, Bonner LA, Cueva JP, Maglathlin R, McCorvy JD, Marona-Lewicka D, Lill MA, Nichols DE. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. Acs Chemical Neuroscience. 4: 96-109. PMID 23336049 DOI: 10.1021/cn3000668  1
2012 Cueva JP, Chemel BR, Juncosa JI, Lill MA, Watts VJ, Nichols DE. Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines. European Journal of Medicinal Chemistry. 48: 97-107. PMID 22204903 DOI: 10.1016/j.ejmech.2011.11.039  1
2011 Cueva JP, Gallardo-Godoy A, Juncosa JI, Vidi PA, Lill MA, Watts VJ, Nichols DE. Probing the steric space at the floor of the D1 dopamine receptor orthosteric binding domain: 7α-, 7β-, 8α-, and 8β-methyl substituted dihydrexidine analogues. Journal of Medicinal Chemistry. 54: 5508-21. PMID 21714510 DOI: 10.1021/jm200334c  1
2011 Clark LH, Cueva JP, McCorvy JD, Harland AA, Watts VJ, Nichols DE. C-Ring expanded analogs of doxanthrine: Conformation plays a critical role Arkivoc. 2010: 125-138.  1
2009 Przybyla JA, Cueva JP, Chemel BR, Hsu KJ, Riese DJ, McCorvy JD, Chester JA, Nichols DE, Watts VJ. Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D(1) receptor agonist, and a reversal of enantioselectivity at D(1) versus alpha(2C) adrenergic receptors. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 138-46. PMID 19028082 DOI: 10.1016/j.euroneuro.2008.10.002  1
2009 Cueva JP, Nichols DE. A novel and efficient synthesis of dihydrexidine Synthesis. 715-720. DOI: 10.1055/s-0028-1083359  1
2006 Cueva JP, Giorgioni G, Grubbs RA, Chemel BR, Watts VJ, Nichols DE. trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist. Journal of Medicinal Chemistry. 49: 6848-57. PMID 17154515 DOI: 10.1021/jm0604979  1
Low-probability matches
2015 Cueva JP, Roche C, Ostovar M, Kumar V, Clark MJ, Hillhouse TM, Lewis JW, Traynor JR, Husbands SM. C7β-Methyl Analogues of the Orvinols: The Discovery of Kappa Opioid Antagonists with Nociceptin/Orphanin FQ Peptide (NOP) Receptor Partial Agonism and Low, or Zero, Efficacy at Mu Opioid Receptors. Journal of Medicinal Chemistry. 58: 4242-9. PMID 25898137 DOI: 10.1021/acs.jmedchem.5b00130  0.01
2014 Kormos CM, Cueva JP, Gichinga MG, Runyon SP, Thomas JB, Brieaddy LE, Mascarella SW, Gilmour BP, Navarro HA, Carroll FI. Effect of the 3- and 4-methyl groups on the opioid receptor properties of N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines. Journal of Medicinal Chemistry. 57: 3140-7. PMID 24635568 DOI: 10.1021/jm500184j  0.01
2013 Kormos CM, Jin C, Cueva JP, Runyon SP, Thomas JB, Brieaddy LE, Mascarella SW, Navarro HA, Gilmour BP, Carroll FI. Discovery of N-{4-[(3-hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide analogues as selective kappa opioid receptor antagonists. Journal of Medicinal Chemistry. 56: 4551-67. PMID 23651437 DOI: 10.1021/jm400275h  0.01
2010 Carroll FI, Cueva JP, Thomas JB, Mascarella SW, Runyon SP, Navarro HA. 1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists. Acs Medicinal Chemistry Letters. 1: 365-369. PMID 21116435 DOI: 10.1021/ml100126b  0.01
2009 Cueva JP, Cai TB, Mascarella SW, Thomas JB, Navarro HA, Carroll FI. Synthesis and in vitro opioid receptor functional antagonism of methyl-substituted analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Journal of Medicinal Chemistry. 52: 7463-72. PMID 19954245 DOI: 10.1021/jm900756t  0.01
1995 Egel RT, Cueva JP, Adair RL. Posttraumatic childhood lumbosacral plexus neuropathy. Pediatric Neurology. 12: 62-4. PMID 7748364 DOI: 10.1016/0887-8994(94)00105-B  0.01
1994 Cueva JP, Egel RT. Anterior fontanel herniation in group B streptococcus meningitis in newborns. Pediatric Neurology. 10: 332-4. PMID 8068163 DOI: 10.1016/0887-8994(94)90133-3  0.01
1988 Cueva JP, Hsueh W. Role of oxygen derived free radicals in platelet activating factor induced bowel necrosis. Gut. 29: 1207-12. PMID 3197995 DOI: 10.1136/gut.29.9.1207  0.01
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