David W. Machacek, Ph.D. - Related publications

Emory University, Atlanta, GA 
spinal cord physiology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Abela AR, Browne CJ, Sargin D, Prevot TD, Ji XD, Li Z, Lambe EK, Fletcher PJ. Median raphe serotonin neurons promote anxiety-like behavior via inputs to the dorsal hippocampus. Neuropharmacology. 107985. PMID 32035145 DOI: 10.1016/j.neuropharm.2020.107985   
2020 Bubak AN, Watt MJ, Yaeger JDW, Renner KJ, Swallow JG. The stalk-eyed fly as a model for aggression - is there a conserved role for 5-HT between vertebrates and invertebrates? The Journal of Experimental Biology. 223. PMID 31896721 DOI: 10.1242/jeb.132159   
2020 Perim RR, Fields DP, Mitchell GS. Spinal AMP Kinase Activity Differentially Regulates Phrenic Motor Plasticity. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 31971473 DOI: 10.1152/japplphysiol.00546.2019   
2020 Cruz-Corchado J, Ooi FK, Das S, Prahlad V. Global Transcriptome Changes That Accompany Alterations in Serotonin Levels in . G3 (Bethesda, Md.). PMID 31996358 DOI: 10.1534/g3.120.401088   
2020 Annamalai B, Ragu Varman D, Horton RE, Daws LC, Jayanthi LD, Ramamoorthy S. Histamine Receptors Regulate the Activity, Surface Expression and Phosphorylation of Serotonin Transporters. Acs Chemical Neuroscience. PMID 31916747 DOI: 10.1021/acschemneuro.9b00664   
2020 Li C, Meng F, Garza JC, Liu J, Lei Y, Kirov SA, Guo M, Lu XY. Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons. Molecular Psychiatry. PMID 31980728 DOI: 10.1038/s41380-020-0649-0   
2020 Emery S, Fieux S, Vidal B, Courault P, Bouvard S, Tourvieille C, Iecker T, Billard T, Zimmer L, Lancelot S. Preclinical validation of [F]2FNQ1P as a specific PET radiotracer of 5-HT receptors in rat, pig, non-human primate and human brain tissue. Nuclear Medicine and Biology. 82: 57-63. PMID 32006785 DOI: 10.1016/j.nucmedbio.2020.01.006   
2020 Ryu Y, Maekawa T, Yoshino D, Sakitani N, Takashima A, Inoue T, Suzurikawa J, Toyohara J, Tago T, Makuuchi M, Fujita N, Sawada K, Murase S, Watanave M, Hirai H, et al. Mechanical Regulation Underlies Effects of Exercise on Serotonin-Induced Signaling in the Prefrontal Cortex Neurons. Iscience. 23: 100874. PMID 32062453 DOI: 10.1016/j.isci.2020.100874   
2020 Zhang SR, Wu JL, Chen H, Luo R, Chen WJ, Tang LJ, Li XW, Yang JM, Gao TM. ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31905370 DOI: 10.1038/s41386-020-0601-7   
2020 Yang J, Huang Q, Liu H, Zhou X, Huang Z, Peng Q, Liu C. 4-Nonylphenol and 4-tert-octylphenol induce anxiety-related behaviors through alternation of 5-HT receptors and transporters in the prefrontal cortex. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 108701. PMID 31911191 DOI: 10.1016/j.cbpc.2020.108701   
2020 Abela AR, Ji XD, Li Z, Lê AD, Fletcher PJ. Clozapine reliably increases the motivation for food: parsing the role of the 5-HT and H receptors. Psychopharmacology. PMID 31897573 DOI: 10.1007/s00213-019-05425-7   
2020 Wang H, Gao XY, Rao F, Yang H, Wang ZY, Liu L, Kuang SJ, Wu Q, Deng CY, Xu JS. Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 31980857 DOI: 10.1007/s00210-020-01813-5   
2020 Cong M, Song J, Chen F, Cao C, Wang S. A surrogate analyte-based LC-MS/MS method for the determination of 5-hydroxytryptamine, kynurenine and tryptophan. Bioanalysis. PMID 32026711 DOI: 10.4155/bio-2019-0267   
2020 Wang W, Zheng L, Li W, Zhu C, Peng W, Han B, Fu W. Design, Synthesis and Structure-activity Relationship Studies of Novel Indolyalkylpiperazine Derivatives as Selective 5-HT Receptor Agonists. Journal of Chemical Information and Modeling. PMID 31913624 DOI: 10.1021/acs.jcim.9b00926   
2020 Olajide TM, Liu T, Liu H, Weng X. Antioxidant properties of two novel lipophilic derivatives of hydroxytyrosol. Food Chemistry. 315: 126197. PMID 32018079 DOI: 10.1016/j.foodchem.2020.126197   
2020 Xia J, Zhang Q, Wang Y, Luan J, Yang J, Cong R, Wang Z, Song N. Association of NE, leptin and 5-HT with electrophysiological parameters in patients with primary premature ejaculation. Andrology. PMID 32068350 DOI: 10.1111/andr.12773   
2020 Pujol CN, Dupuy V, Séveno M, Runtz L, Bockaert J, Marin P, Chaumont-Dubel S. Dynamic interactions of the 5-HT receptor with protein partners control dendritic tree morphogenesis. Science Signaling. 13. PMID 32047117 DOI: 10.1126/scisignal.aax9520   
2020 Mao Q, Zhang B, Li W, Tian S, Shui W, Ye N. Identification of Novel 1-O-substituted Aporphine Analogues as Potent 5-HT2C Receptor Agonists. Acs Chemical Neuroscience. PMID 31968160 DOI: 10.1021/acschemneuro.9b00563   
2020 Guros NB, Balijepalli A, Klauda JB. Microsecond-timescale simulations suggest 5-HT-mediated preactivation of the 5-HT serotonin receptor. Proceedings of the National Academy of Sciences of the United States of America. 117: 405-414. PMID 31871207 DOI: 10.1073/pnas.1908848117   
2020 Arashi H, Sato T, Kobashigawa J, Luikart H, Kobayashi Y, Okada K, Sinha S, Honda Y, Yeung AC, Khush K, Fearon WF. Long-term clinical outcomes with use of an angiotensin-converting enzyme inhibitor early after heart transplantation. American Heart Journal. 222: 30-37. PMID 32007823 DOI: 10.1016/j.ahj.2020.01.003   
2020 Chen J, Xu Y, Fei K, Wang R, He J, Fu L, Shao S, Li K, Zhu K, Zhang W, Wang Z, Yang J. Physiological mechanism underlying the effect of high temperature during anthesis on spikelet-opening of photo-thermo-sensitive genic male sterile rice lines. Scientific Reports. 10: 2210. PMID 32042005 DOI: 10.1038/s41598-020-59183-0   
2020 Ananth M, Bartlett EA, DeLorenzo C, Lin X, Kunkel L, Vadhan NP, Perlman G, Godstrey M, Holzmacher D, Ogden RT, Parsey RV, Huang C. Prediction of lithium treatment response in bipolar depression using 5-HTT and 5-HT PET. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32055965 DOI: 10.1007/s00259-020-04681-6   
2020 Lee JA, Levy DA, Patel KG, Brennan E, Oyer SL. Hair transplantation in frontal fibrosing alopecia and lichen planopilaris: A systematic review. The Laryngoscope. PMID 32045028 DOI: 10.1002/lary.28551   
2020 De Deurwaerdère P, Bharatiya R, Chagraoui A, Di Giovanni G. Constitutive activity of 5-HT receptors: Factual analysis. Neuropharmacology. 107967. PMID 31958408 DOI: 10.1016/j.neuropharm.2020.107967   
2020 Hussein I, Al Halabi M, Kowash M, Salami A, Ouatik N, Yang YM, Duggal M, Chandwani N, Nazzal H, Albadri S, Roberts A, Al-Jundi S, Nzomiwu C, El Shahawy O, Attaie A, et al. Use of the Hall technique by specialist paediatric dentists: a global perspective. British Dental Journal. 228: 33-38. PMID 31925371 DOI: 10.1038/s41415-019-1100-2   
2020 Zhang JG, Huang XY, Ma YB, Chen JJ, Geng CA. UFLC-PDA-MS/MS Profiling of Seven Uncaria Species Integrated with Melatonin/5-Hydroxytryptamine Receptors Agonistic Assay. Natural Products and Bioprospecting. PMID 31933166 DOI: 10.1007/s13659-020-00230-8   
2020 Halberstadt AL, Chatha M, Klein AK, Wallach J, Brandt SD. Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species. Neuropharmacology. 107933. PMID 31917152 DOI: 10.1016/j.neuropharm.2019.107933   
2020 Iihara H, Shimokawa M, Hayasaki Y, Fujita Y, Abe M, Takenaka M, Yamamoto S, Arai T, Sakurai M, Mori M, Nakamura K, Kado N, Murase S, Shimaoka R, Suzuki A, et al. Efficacy and safety of 5 mg olanzapine combined with aprepitant, granisetron and dexamethasone to prevent carboplatin-induced nausea and vomiting in patients with gynecologic cancer: A multi-institution phase II study. Gynecologic Oncology. PMID 31926638 DOI: 10.1016/j.ygyno.2020.01.004   
2020 Pinheiro Sartori D, de Oliveira NF, Valentim JT, da Silva DMA, Serra Vasconcelos A, Maia Oliveira IC, de Castro Chaves R, Cavalcanti Capibaribe VC, de Carvalho AMR, de Oliveira Rebouças M, Macêdo D, Maia Chaves Filho AJ, de França Fonteles MM, Chavez Gutierrez SJ, Barbosa-Filho JM, et al. Involvement of monoaminergic targets in the antidepressant- and anxiolytic-like effects of the synthetic alkamide Riparin IV: elucidation of further mechanisms through pharmacological, neurochemistry and computational approaches. Behavioural Brain Research. 112487. PMID 31987932 DOI: 10.1016/j.bbr.2020.112487   
2020 Fisher R, Hikima A, Morris R, Jackson MJ, Rose S, Varney MA, Depoortere R, Newman-Tancredi A. The selective 5-HT receptor agonist, NLX-112, exerts anti-dyskinetic and anti-parkinsonian-like effects in MPTP-treated marmosets. Neuropharmacology. 107997. PMID 32057799 DOI: 10.1016/j.neuropharm.2020.107997   
2020 Sullivan HJ, Tursi A, Moore K, Campbell A, Floyd C, Wu C. Binding interactions of ergotamine and dihydroergotamine to 5-hydroxytryptamine receptor 1B (5-HT1b) using Molecular Dynamics Simulations and Dynamic Network Analysis. Journal of Chemical Information and Modeling. PMID 32078320 DOI: 10.1021/acs.jcim.9b01082   
2020 Wang H, Lane K, Lou Z, Parker S, Placke M. Genotoxicity and carcinogenicity risk assessment of prucalopride, a selective 5-hydroxytryptamine 4 receptor agonist. Regulatory Toxicology and Pharmacology : Rtp. 104586. PMID 31972188 DOI: 10.1016/j.yrtph.2020.104586   
2020 Brandt L, Jones JD, Martinez S, Manubay JM, Mogali S, Ramey T, Levin FR, Comer SD. Effects of lorcaserin on oxycodone self-administration and subjective responses in participants with opioid use disorder. Drug and Alcohol Dependence. 107859. PMID 31980285 DOI: 10.1016/j.drugalcdep.2020.107859   
2020 Silva ON, Franco OL, Neves BJ, Morais ÁCB, De Oliveira Neto JR, da Cunha LC, Naves LM, Pedrino GR, Costa EA, Fajemiroye JO. Involvement of the gabaergic, serotonergic and glucocorticoid mechanism in the anxiolytic-like effect of mastoparan-L. Neuropeptides. 102027. PMID 32059939 DOI: 10.1016/j.npep.2020.102027   
2020 Kaya MS, Kınay Taran P, Bakkal M. Temporomandibular dysfunction assessment in children treated with the Hall Technique: A pilot study. International Journal of Paediatric Dentistry. PMID 31991506 DOI: 10.1111/ipd.12620   
2020 Yi F, Rouzbeh N, Hansen KB, Xu Y, Fanger CM, Gordon E, Paschetto K, Menniti FS, Volkmann RA. PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits. Neuropharmacology. 107971. PMID 31987864 DOI: 10.1016/j.neuropharm.2020.107971   
2020 Zhou X, He D, Yan X, Chen X, Li R, Zhang G, Wang J. Moxonidine inhibits excitatory inputs to airway vagal preganglionic neurons via activation of both α-adrenoceptors and imidazoline I1 receptors. Brain Research. 146695. PMID 32007398 DOI: 10.1016/j.brainres.2020.146695   
2020 Tsai M, Case M, Ardayfio P, Hochstetler H, Wilbraham D. Effects of Lasmiditan on Cardiovascular Parameters and Pharmacokinetics in Healthy Subjects Receiving Oral Doses of Propranolol. Clinical Pharmacology in Drug Development. PMID 31950732 DOI: 10.1002/cpdd.768   
2020 Yamamoto Y, Taniguchi T, Inazumi T, Iwamura R, Yoneda K, Odani-Kawabata N, Matsugi T, Sugimoto Y, Shams NK. Effects of the Selective EP2 Receptor Agonist Omidenepag on Adipocyte Differentiation in 3T3-L1 Cells. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 31934812 DOI: 10.1089/jop.2019.0079   
2020 Ju C, Song Y, Kong D. GLR3.5-modulated seed germination involves GA and ROS signaling. Plant Signaling & Behavior. 1729537. PMID 32063094 DOI: 10.1080/15592324.2020.1729537   
2020 Milior G, Morin-Brureau M, Chali F, Le Duigou C, Savary E, Huberfeld G, Rouach N, Pallud J, Capelle L, Navarro V, Mathon B, Clemenceau S, Miles R. Distinct P2Y receptors mediate extension and retraction of microglial processes in epileptic and peri-tumoral human tissue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31896671 DOI: 10.1523/JNEUROSCI.0218-19.2019   
2020 Iriyama T, Wang W, Parchim NF, Sayama S, Kumasawa K, Nagamatsu T, Song A, Xia Y, Kellems RE. Reciprocal upregulation of hypoxia-inducible factor-1α and persistently enhanced placental adenosine signaling contribute to the pathogenesis of preeclampsia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31930569 DOI: 10.1096/fj.201902583R   
2020 Bui AD, Grob SR, Tao JP. 5-Fluorouracil Management of Oculofacial Scars: A Systematic Literature Review. Ophthalmic Plastic and Reconstructive Surgery. PMID 31923097 DOI: 10.1097/IOP.0000000000001532   
2020 Chen S, Liao B, Jin X, Wei T, He Q, Lin Y, Ai J, Gong L, Li H, Wang K. M receptor modulates extracellular matrix synthesis via ERK1/2 signaling pathway in human bladder smooth muscle cells. Journal of Cellular Biochemistry. PMID 32065420 DOI: 10.1002/jcb.29688   
2020 Zhao Y, van Woudenbergh E, Zhu J, Heck AJR, van Kessel KPM, de Haas CJC, Aerts PC, van Strijp JAG, McCarthy AJ. The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils. Journal of Immunology (Baltimore, Md. : 1950). PMID 31915259 DOI: 10.4049/jimmunol.1900852   
2020 Li N, Liu Q, Li RT, Sun Q, Jiang YM, Ye J. Anti-arthritic Effect of the Spirocyclopiperazinium Salt Compound LXM-15 in Rats and Its Underlying Mechanism. Inflammation. PMID 31950322 DOI: 10.1007/s10753-020-01177-1   
2020 Elmadany N, de Almeida Sassi F, Wendt S, Logiacco F, Visser J, Haage V, Hambardzumyan D, Wolf S, Kettenmann H, Semtner M. The VGF-derived peptide TLQP21 impairs purinergic control of chemotaxis and phagocytosis in mouse microglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32060170 DOI: 10.1523/JNEUROSCI.1458-19.2020   
2020 Li T, Hu SM, Pang XY, Wang JF, Yin JY, Li FH, Wang J, Yang XQ, Xia B, Liu YH, Song WG, Guo SD. The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα. Journal of Cellular and Molecular Medicine. PMID 31981312 DOI: 10.1111/jcmm.15012   
2020 Lv C, Huang L. Xenobiotic receptors in mediating the effect of sepsis on drug metabolism. Acta Pharmaceutica Sinica. B. 10: 33-41. PMID 31993305 DOI: 10.1016/j.apsb.2019.12.003   
2020 Davidsson Ö, Nilsson K, Brånalt J, Andersson T, Berggren K, Chen Y, Fjellström O, Gradén H, Gustafsson L, Hermansson NO, Jansen F, Johannesson P, Ohlsson B, Tyrchan C, Wellner A, et al. Identification of novel GPR81 agonist lead series for target biology evaluation. Bioorganic & Medicinal Chemistry Letters. 126953. PMID 31932225 DOI: 10.1016/j.bmcl.2020.126953