| Year |
Citation |
Score |
| 2023 |
Kambali M, Li Y, Unichenko P, Pliego JF, Yadav R, Liu J, McGuinness P, Cobb JG, Wang M, Nagarajan R, Lyu J, Vongsouthi V, Jackson CJ, Engin E, Coyle JT, ... ... Rudolph U, et al. A marker chromosome in psychosis identifies glycine decarboxylase (GLDC) as a novel regulator of neuronal and synaptic function in the hippocampus. Biorxiv : the Preprint Server For Biology. PMID 37398055 DOI: 10.1101/2023.05.29.542745 |
0.522 |
|
| 2023 |
Puig-Bosch X, Ballmann M, Bieletzki S, Antkowiak B, Rudolph U, Zeilhofer HU, Rammes G. Neurosteroids Mediate Neuroprotection in an In Vitro Model of Hypoxic/Hypoglycaemic Excitotoxicity via δ-GABA Receptors without Affecting Synaptic Plasticity. International Journal of Molecular Sciences. 24. PMID 37240402 DOI: 10.3390/ijms24109056 |
0.35 |
|
| 2023 |
Zhu M, Abdulzahir A, Perkins MG, Chu CC, Krause BM, Casey C, Lennertz R, Ruhl D, Hentschke H, Nagarajan R, Chapman ER, Rudolph U, Fanselow MS, Pearce RA. Control of contextual memory through interneuronal α5-GABA receptors. Pnas Nexus. 2: pgad065. PMID 37056471 DOI: 10.1093/pnasnexus/pgad065 |
0.324 |
|
| 2022 |
Puig-Bosch X, Bieletzki S, Zeilhofer HU, Rudolph U, Antkowiak B, Rammes G. Midazolam at low nanomolar concentrations affects long-term potentiation and synaptic transmission predominantly via the α1-GABAA receptor subunit in mice. Anesthesiology. PMID 35285894 DOI: 10.1097/ALN.0000000000004202 |
0.318 |
|
| 2021 |
Troppoli TA, Zanos P, Georgiou P, Gould TD, Rudolph U, Thompson SM. Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. Biological Psychiatry. PMID 35120711 DOI: 10.1016/j.biopsych.2021.11.024 |
0.433 |
|
| 2021 |
Belelli D, Hales TG, Lambert JJ, Luscher B, Olsen R, Peters JA, Rudolph U, Sieghart W. GABA receptors in GtoPdb v.2021.3. Iuphar/Bps Guide to Pharmacology Cite. 2021. PMID 35005623 DOI: 10.2218/gtopdb/F72/2021.3 |
0.417 |
|
| 2021 |
Sinha R, Grimes WN, Wallin J, Ebbinghaus BN, Luu K, Cherry T, Rieke F, Rudolph U, Wong RO, Hoon M. Transient expression of a GABA receptor subunit during early development is critical for inhibitory synapse maturation and function. Current Biology : Cb. PMID 34433078 DOI: 10.1016/j.cub.2021.07.059 |
0.339 |
|
| 2021 |
Benham RS, Choi C, Hodgson NW, Hewage NB, Kastli R, Donahue RJ, Muschamp JW, Engin E, Carlezon WA, Hensch TK, Rudolph U. α2-containing γ-aminobutyric acid type A receptors promote stress resiliency in male mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34408277 DOI: 10.1038/s41386-021-01144-w |
0.671 |
|
| 2021 |
Sawant A, Ebbinghaus BN, Bleckert A, Gamlin C, Yu WQ, Berson D, Rudolph U, Sinha R, Hoon M. Organization and emergence of a mixed GABA-glycine retinal circuit that provides inhibition to mouse ON-sustained alpha retinal ganglion cells. Cell Reports. 34: 108858. PMID 33730586 DOI: 10.1016/j.celrep.2021.108858 |
0.356 |
|
| 2020 |
Engin E, Sigal M, Benke D, Zeller A, Rudolph U. Bidirectional regulation of distinct memory domains by α5-subunit-containing GABA receptors in CA1 pyramidal neurons. Learning & Memory (Cold Spring Harbor, N.Y.). 27: 423-428. PMID 32934095 DOI: 10.1101/Lm.052084.120 |
0.632 |
|
| 2020 |
Kreuzer M, Butovas S, García PS, Schneider G, Schwarz C, Rudolph U, Antkowiak B, Drexler B. Propofol Affects Cortico-Hippocampal Interactions via β3 Subunit-Containing GABA Receptors. International Journal of Molecular Sciences. 21. PMID 32823959 DOI: 10.3390/Ijms21165844 |
0.494 |
|
| 2020 |
Levy D, Morgan C, Bodkin JA, Coleman M, Godfrey L, Carvalho C, Grochowski C, Kaufman M, Jensen JE, TCW J, Brennand K, McCarthy S, Malhotra D, Sebat J, Goff D, ... ... Rudolph U, et al. Partial Pharmacological “Rescue” and MRS spectroscopy in Two Carriers of a Rare Marker Chromosome Containing Extra Copies of the GLDC Gene Encoding a Glycine-Degrading Enzyme Implicate NMDA Receptor Hypofunction in Psychosis Biological Psychiatry. 87: S98-S99. DOI: 10.1016/J.Biopsych.2020.02.272 |
0.306 |
|
| 2019 |
Rudolph U, Moss SJ. Modulating anxiety and activity. Science (New York, N.Y.). 366: 185-186. PMID 31601757 DOI: 10.1126/science.aaz3176 |
0.474 |
|
| 2019 |
Hofmann JI, Schwarz C, Rudolph U, Antkowiak B. Effects of Diazepam on Low-Frequency and High-Frequency Electrocortical γ-Power Mediated by α1- and α2-GABA Receptors. International Journal of Molecular Sciences. 20. PMID 31315211 DOI: 10.3390/Ijms20143486 |
0.494 |
|
| 2019 |
Bodkin JA, Coleman MJ, Godfrey LJ, Carvalho CMB, Morgan CJ, Suckow RF, Anderson T, Ongur D, Kaufman MJ, Lewandowski KE, Siegel AJ, Waldstreicher E, Grochowski CM, Javitt DC, Rujescu D, ... ... Rudolph U, et al. Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene. Biological Psychiatry. PMID 31279534 DOI: 10.1016/J.Biopsych.2019.04.031 |
0.303 |
|
| 2019 |
Belelli D, Hales TG, Lambert JJ, Luscher B, Olsen R, Peters JA, Rudolph U, Sieghart W. GABAA receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f72/2019.4 |
0.377 |
|
| 2018 |
Neumann E, Rudolph U, Knutson DE, Li G, Cook JM, Hentschke H, Antkowiak B, Drexler B. Zolpidem Activation of Alpha 1-Containing GABA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons. Frontiers in Pharmacology. 9: 1523. PMID 30687091 DOI: 10.3389/Fphar.2018.01523 |
0.531 |
|
| 2018 |
Neumann E, Ralvenius WT, Acuña MA, Rudolph U, Zeilhofer HU. TP003 is a non-selective benzodiazepine site agonist that induces anxiolysis via α2GABA receptors. Neuropharmacology. PMID 30240781 DOI: 10.1016/j.neuropharm.2018.09.026 |
0.467 |
|
| 2018 |
Ralvenius WT, Neumann E, Pagani M, Acuña MA, Wildner H, Benke D, Fischer N, Rostaher A, Schwager S, Detmar M, Frauenknecht K, Aguzzi A, Hubbs JL, Rudolph U, Favrot C, et al. Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA receptors. Nature Communications. 9: 3230. PMID 30104684 DOI: 10.1038/S41467-018-05709-0 |
0.327 |
|
| 2018 |
Engin E, Benham RS, Rudolph U. An Emerging Circuit Pharmacology of GABA Receptors. Trends in Pharmacological Sciences. PMID 29903580 DOI: 10.1016/J.Tips.2018.04.003 |
0.647 |
|
| 2018 |
Seifi M, Rodaway S, Rudolph U, Swinny JD. GABA Receptor Subtypes Regulate Stress-induced Colon Inflammation in Mice. Gastroenterology. PMID 29802853 DOI: 10.1053/j.gastro.2018.05.033 |
0.366 |
|
| 2018 |
Ralvenius WT, Neumann E, Pagani M, Acuña MA, Wildner H, Benke D, Fischer N, Rostaher A, Schwager S, Detmar M, Frauenknecht K, Aguzzi A, Hubbs JL, Rudolph U, Favrot C, et al. Itch suppression in mice and dogs by modulation of spinal alpha 2 and alpha 3GABA(A) receptors Nature Communications. 9: 3230. DOI: 10.3929/Ethz-B-000283986 |
0.468 |
|
| 2017 |
Benham RS, Hewage NB, Suckow RF, Engin E, Rudolph U. Corrigendum to "Prodepressant- and anxiogenic-like effects of serotonin-selective, but not noradrenaline-selective, antidepressant agents in mice lacking α2-containing GABAA receptors" [Behav. Brain Res. 332 (2017) 172-179]. Behavioural Brain Research. PMID 29070432 DOI: 10.1016/J.Bbr.2017.10.006 |
0.651 |
|
| 2017 |
Balk M, Hentschke H, Rudolph U, Antkowiak B, Drexler B. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Scientific Reports. 7: 3503. PMID 28615640 DOI: 10.1038/S41598-017-03154-5 |
0.386 |
|
| 2017 |
Benham RS, Hewage NB, Suckow RF, Engin E, Rudolph U. Prodepressant- and anxiogenic-like effects of serotonin-selective, but not noradrenaline-selective, antidepressant agents in mice lacking α2-containing GABAA receptors. Behavioural Brain Research. PMID 28587819 DOI: 10.1016/J.Bbr.2017.05.063 |
0.659 |
|
| 2017 |
Möhler H, Rudolph U. Disinhibition, an emerging pharmacology of learning and memory. F1000research. 6. PMID 28232865 DOI: 10.12688/F1000Research.9947.1 |
0.64 |
|
| 2016 |
Newman EL, Gunner G, Huynh P, Gachette D, Moss SJ, Smart TG, Rudolph U, DeBold JF, Miczek KA. Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice. Alcoholism, Clinical and Experimental Research. PMID 27717041 DOI: 10.1111/Acer.13215 |
0.548 |
|
| 2016 |
Ralvenius WT, Acuña MA, Benke D, Matthey A, Daali Y, Rudolph U, Desmeules J, Zeilhofer HU, Besson M. The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia. Neuropharmacology. PMID 27392635 DOI: 10.1016/j.neuropharm.2016.07.004 |
0.42 |
|
| 2016 |
Deprez F, Vogt F, Floriou-Servou A, Lafourcade C, Rudolph U, Tyagarajan SK, Fritschy JM. Partial inactivation of GABAA receptors containing the α5 subunit affects the development of adult-born dentate gyrus granule cells. The European Journal of Neuroscience. PMID 27364953 DOI: 10.1111/Ejn.13329 |
0.437 |
|
| 2016 |
Antkowiak B, Rudolph U. New insights in the systemic and molecular underpinnings of general anesthetic actions mediated by γ-aminobutyric acid A receptors. Current Opinion in Anaesthesiology. PMID 27168087 DOI: 10.1097/Aco.0000000000000358 |
0.43 |
|
| 2016 |
Behlke LM, Foster RA, Liu J, Benke D, Benham RS, Nathanson A, Yee BK, Zeilhofer HU, Engin E, Rudolph U. A Pharmaco-Genetic 'Restriction-of-Function' Approach Reveals Evidence for Anxiolytic-Like Actions Mediated by α5-Containing GABAA Receptors in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27067130 DOI: 10.1038/Npp.2016.49 |
0.635 |
|
| 2016 |
Engin E, Smith KS, Gao Y, Nagy D, Foster RA, Tsvetkov E, Keist R, Crestani F, Fritschy JM, Bolshakov VY, Hajos M, Heldt SA, Rudolph U. Modulation of anxiety and fear via distinct intrahippocampal circuits. Elife. 5. PMID 26971710 DOI: 10.7554/Elife.14120 |
0.641 |
|
| 2016 |
Engin E, Smith KS, Gao Y, Nagy D, Foster RA, Tsvetkov E, Keist R, Crestani F, Fritschy J, Bolshakov VY, Hajos M, Heldt SA, Rudolph U. Author response: Modulation of anxiety and fear via distinct intrahippocampal circuits Elife. DOI: 10.7554/Elife.14120.023 |
0.547 |
|
| 2015 |
Pangratz-Fuehrer S, Sieghart W, Rudolph U, Parada I, Huguenard JR. Early Postnatal Switch in GABAAR α Subunits in the Reticular Thalamic Nucleus. Journal of Neurophysiology. jn.00905.2015. PMID 26631150 DOI: 10.1152/jn.00905.2015 |
0.406 |
|
| 2015 |
Vien TN, Modgil A, Abramian AM, Jurd R, Walker J, Brandon NJ, Terunuma M, Rudolph U, Maguire J, Davies PA, Moss SJ. Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders. Proceedings of the National Academy of Sciences of the United States of America. 112: 14805-10. PMID 26627235 DOI: 10.1073/Pnas.1514657112 |
0.733 |
|
| 2015 |
Engin E, Zarnowska ED, Benke D, Tsvetkov E, Sigal M, Keist R, Bolshakov VY, Pearce RA, Rudolph U. Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13698-712. PMID 26446222 DOI: 10.1523/Jneurosci.1370-15.2015 |
0.632 |
|
| 2015 |
Newman EL, Smith KS, Takahashi A, Chu A, Hwa LS, Chen Y, DeBold JF, Rudolph U, Miczek KA. α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice. Psychopharmacology. PMID 26381154 DOI: 10.1007/S00213-015-4069-9 |
0.494 |
|
| 2015 |
Botta P, Demmou L, Kasugai Y, Markovic M, Xu C, Fadok JP, Lu T, Poe MM, Xu L, Cook JM, Rudolph U, Sah P, Ferraguti F, Lüthi A. Regulating anxiety with extrasynaptic inhibition. Nature Neuroscience. PMID 26322928 DOI: 10.1038/Nn.4102 |
0.348 |
|
| 2015 |
Rodgers FC, Zarnowska ED, Laha KT, Engin E, Zeller A, Keist R, Rudolph U, Pearce RA. Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9707-16. PMID 26134653 DOI: 10.1523/Jneurosci.0315-15.2015 |
0.619 |
|
| 2015 |
Ralvenius WT, Benke D, Acuña MA, Rudolph U, Zeilhofer HU. Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype. Nature Communications. 6: 6803. PMID 25865415 DOI: 10.1038/ncomms7803 |
0.456 |
|
| 2015 |
Zarnowska ED, Rodgers FC, Oh I, Rau V, Lor C, Laha KT, Jurd R, Rudolph U, Eger EI, Pearce RA. Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor. Neuropharmacology. 93: 171-8. PMID 25680234 DOI: 10.1016/J.Neuropharm.2015.01.011 |
0.754 |
|
| 2015 |
Crestani F, Rudolph U. Behavioral functions of GABAA receptor subtypes--the Zurich experience. Advances in Pharmacology (San Diego, Calif.). 72: 37-51. PMID 25600366 DOI: 10.1016/bs.apha.2014.10.001 |
0.48 |
|
| 2015 |
Eckle VS, Rudolph U, Antkowiak B, Grasshoff C. Propofol modulates phasic and tonic GABAergic currents in spinal ventral horn interneurones. British Journal of Anaesthesia. 114: 491-8. PMID 25150989 DOI: 10.1093/Bja/Aeu269 |
0.374 |
|
| 2014 |
Labrakakis C, Rudolph U, De Koninck Y. The heterogeneity in GABAA receptor-mediated IPSC kinetics reflects heterogeneity of subunit composition among inhibitory and excitatory interneurons in spinal lamina II. Frontiers in Cellular Neuroscience. 8: 424. PMID 25565959 DOI: 10.3389/Fncel.2014.00424 |
0.486 |
|
| 2014 |
Martin CB, Gassmann M, Chevarin C, Hamon M, Rudolph U, Bettler B, Lanfumey L, Mongeau R. Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress. Journal of Neurochemistry. 131: 566-72. PMID 25113583 DOI: 10.1111/Jnc.12929 |
0.519 |
|
| 2014 |
Seifi M, Brown JF, Mills J, Bhandari P, Belelli D, Lambert JJ, Rudolph U, Swinny JD. Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10361-78. PMID 25080596 DOI: 10.1523/Jneurosci.0441-14.2014 |
0.428 |
|
| 2014 |
Corteen NL, Carter JA, Rudolph U, Belelli D, Lambert JJ, Swinny JD. Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus. Brain Structure & Function. PMID 24973971 DOI: 10.1007/S00429-014-0824-7 |
0.439 |
|
| 2014 |
Riccio A, Li Y, Tsvetkov E, Gapon S, Yao GL, Smith KS, Engin E, Rudolph U, Bolshakov VY, Clapham DE. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3653-67. PMID 24599464 DOI: 10.1523/Jneurosci.2274-13.2014 |
0.648 |
|
| 2014 |
Engin E, Bakhurin KI, Smith KS, Hines RM, Reynolds LM, Tang W, Sprengel R, Moss SJ, Rudolph U. Neural basis of benzodiazepine reward: requirement for α2 containing GABAA receptors in the nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1805-15. PMID 24553732 DOI: 10.1038/Npp.2014.41 |
0.796 |
|
| 2014 |
Benham RS, Engin E, Rudolph U. Diversity of neuronal inhibition: a path to novel treatments for neuropsychiatric disorders. Jama Psychiatry. 71: 91-3. PMID 24196284 DOI: 10.1001/Jamapsychiatry.2013.3059 |
0.659 |
|
| 2014 |
Rudolph U, Möhler H. GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism. Annual Review of Pharmacology and Toxicology. 54: 483-507. PMID 24160694 DOI: 10.1146/Annurev-Pharmtox-011613-135947 |
0.432 |
|
| 2014 |
Paul J, Yévenes GE, Benke D, Di Lio A, Ralvenius WT, Witschi R, Scheurer L, Cook JM, Rudolph U, Fritschy JM, Zeilhofer HU. Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 477-87. PMID 24045508 DOI: 10.1038/Npp.2013.221 |
0.387 |
|
| 2014 |
Mongeau R, Martin CBP, Chevarin C, Gassman M, Hamon M, Rudolph U, Bettler B, Lanfumey L. P.1.g.054 Effect of genetic and pharmacological blockade of GABA receptors on a serotonergic regulation of stress European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70365-7 |
0.425 |
|
| 2013 |
Christian CA, Herbert AG, Holt RL, Peng K, Sherwood KD, Pangratz-Fuehrer S, Rudolph U, Huguenard JR. Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor. Neuron. 78: 1063-74. PMID 23727119 DOI: 10.1016/J.Neuron.2013.04.026 |
0.505 |
|
| 2013 |
Van't Veer A, Bechtholt AJ, Onvani S, Potter D, Wang Y, Liu-Chen LY, Schütz G, Chartoff EH, Rudolph U, Cohen BM, Carlezon WA. Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1585-97. PMID 23446450 DOI: 10.1038/Npp.2013.58 |
0.379 |
|
| 2013 |
Drexler B, Zinser S, Huang S, Poe MM, Rudolph U, Cook JM, Antkowiak B. Enhancing the function of alpha5-subunit-containing GABAA receptors promotes action potential firing of neocortical neurons during up-states. European Journal of Pharmacology. 703: 18-24. PMID 23380687 DOI: 10.1016/J.Ejphar.2013.01.034 |
0.477 |
|
| 2013 |
Ohtsuka N, Badurek S, Busslinger M, Benes FM, Minichiello L, Rudolph U. GABAergic neurons regulate lateral ventricular development via transcription factor Pax5. Genesis (New York, N.Y. : 2000). 51: 234-45. PMID 23349049 DOI: 10.1002/Dvg.22370 |
0.344 |
|
| 2013 |
Straub CJ, Lau HM, Parlato R, Schuetz G, Fritschy JM, Rudolph U. Bidirectional regulation of intravenous general anesthetic actions by α3-containing γ-aminobutyric acid A receptors. Anesthesiology. 118: 562-76. PMID 23303487 DOI: 10.1097/ALN.0b013e3182800d76 |
0.524 |
|
| 2013 |
Blednov YA, Benavidez JM, Black M, Chandra D, Homanics GE, Rudolph U, Harris RA. Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication. Neuropharmacology. 67: 46-56. PMID 23147414 DOI: 10.1016/J.Neuropharm.2012.10.016 |
0.441 |
|
| 2013 |
Koester C, Rudolph U, Haenggi T, Papilloud A, Fritschy JM, Crestani F. Dissecting the role of diazepam-sensitive γ-aminobutyric acid type A receptors in defensive behavioral reactivity to mild threat. Pharmacology, Biochemistry, and Behavior. 103: 541-9. PMID 23067879 DOI: 10.1016/j.pbb.2012.10.004 |
0.501 |
|
| 2013 |
Engin E, Bakhurin KI, Smith KS, Hines RM, Reynolds LM, Tang W, Sprengel R, Moss SJ, Rudolph U. S.6.1 - NEURAL BASIS OF BENZODIAZEPINE REWARD Behavioural Pharmacology. 24: e6-e7. DOI: 10.1097/01.Fbp.0000434704.76389.C2 |
0.722 |
|
| 2012 |
Engin E, Liu J, Rudolph U. α2-containing GABA(A) receptors: a target for the development of novel treatment strategies for CNS disorders. Pharmacology & Therapeutics. 136: 142-52. PMID 22921455 DOI: 10.1016/J.Pharmthera.2012.08.006 |
0.703 |
|
| 2012 |
Reynolds LM, Engin E, Tantillo G, Lau HM, Muschamp JW, Carlezon WA, Rudolph U. Differential roles of GABA(A) receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2531-40. PMID 22763624 DOI: 10.1038/Npp.2012.115 |
0.795 |
|
| 2012 |
Pallotto M, Nissant A, Fritschy JM, Rudolph U, Sassoè-Pognetto M, Panzanelli P, Lledo PM. Early formation of GABAergic synapses governs the development of adult-born neurons in the olfactory bulb. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9103-15. PMID 22745509 DOI: 10.1523/Jneurosci.0214-12.2012 |
0.388 |
|
| 2012 |
Marowsky A, Rudolph U, Fritschy JM, Arand M. Tonic inhibition in principal cells of the amygdala: a central role for α3 subunit-containing GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8611-9. PMID 22723702 DOI: 10.1523/JNEUROSCI.4404-11.2012 |
0.463 |
|
| 2012 |
Auferkorte ON, Baden T, Kaushalya SK, Zabouri N, Rudolph U, Haverkamp S, Euler T. GABA(A) receptors containing the α2 subunit are critical for direction-selective inhibition in the retina. Plos One. 7: e35109. PMID 22506070 DOI: 10.1371/Journal.Pone.0035109 |
0.466 |
|
| 2012 |
Smith KS, Engin E, Meloni EG, Rudolph U. Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice. Neuropharmacology. 63: 250-8. PMID 22465203 DOI: 10.1016/J.Neuropharm.2012.03.001 |
0.716 |
|
| 2012 |
Smith KS, Rudolph U. Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABA(A) receptor subtypes. Neuropharmacology. 62: 54-62. PMID 21810433 DOI: 10.1016/j.neuropharm.2011.07.026 |
0.472 |
|
| 2012 |
Yanovsky Y, Schubring S, Fleischer W, Gisselmann G, Zhu XR, Lübbert H, Hatt H, Rudolph U, Haas HL, Sergeeva OA. GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies. Pflã¼Gers Archiv : European Journal of Physiology. 463: 187-99. PMID 21735059 DOI: 10.1007/S00424-011-0988-4 |
0.483 |
|
| 2011 |
Lalive AL, Rudolph U, Lüscher C, Tan KR. Is there a way to curb benzodiazepine addiction? Swiss Medical Weekly. 141: w13277. PMID 22012428 DOI: 10.4414/smw.2011.13277 |
0.355 |
|
| 2011 |
Panzanelli P, Gunn BG, Schlatter MC, Benke D, Tyagarajan SK, Scheiffele P, Belelli D, Lambert JJ, Rudolph U, Fritschy JM. Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells. The Journal of Physiology. 589: 4959-80. PMID 21825022 DOI: 10.1113/Jphysiol.2011.216028 |
0.447 |
|
| 2011 |
Rudolph U, Knoflach F. Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes. Nature Reviews. Drug Discovery. 10: 685-97. PMID 21799515 DOI: 10.1038/nrd3502 |
0.502 |
|
| 2011 |
Bähner F, Weiss EK, Birke G, Maier N, Schmitz D, Rudolph U, Frotscher M, Traub RD, Both M, Draguhn A. Cellular correlate of assembly formation in oscillating hippocampal networks in vitro. Proceedings of the National Academy of Sciences of the United States of America. 108: E607-16. PMID 21768381 DOI: 10.1073/Pnas.1103546108 |
0.364 |
|
| 2011 |
Duveau V, Laustela S, Barth L, Gianolini F, Vogt KE, Keist R, Chandra D, Homanics GE, Rudolph U, Fritschy JM. Spatiotemporal specificity of GABAA receptor-mediated regulation of adult hippocampal neurogenesis. The European Journal of Neuroscience. 34: 362-73. PMID 21722213 DOI: 10.1111/J.1460-9568.2011.07782.X |
0.453 |
|
| 2011 |
Witschi R, Punnakkal P, Paul J, Walczak JS, Cervero F, Fritschy JM, Kuner R, Keist R, Rudolph U, Zeilhofer HU. Presynaptic alpha2-GABAA receptors in primary afferent depolarization and spinal pain control. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8134-42. PMID 21632935 DOI: 10.1523/Jneurosci.6328-10.2011 |
0.517 |
|
| 2011 |
Tan KR, Rudolph U, Lüscher C. Hooked on benzodiazepines: GABAA receptor subtypes and addiction. Trends in Neurosciences. 34: 188-97. PMID 21353710 DOI: 10.1016/j.tins.2011.01.004 |
0.446 |
|
| 2011 |
Drexler B, Antkowiak B, Engin E, Rudolph U. Identification and characterization of anesthetic targets by mouse molecular genetics approaches. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthã©Sie. 58: 178-90. PMID 21174184 DOI: 10.1007/S12630-010-9414-1 |
0.664 |
|
| 2011 |
Vollenweider I, Smith KS, Keist R, Rudolph U. Antidepressant-like properties of α2-containing GABA(A) receptors. Behavioural Brain Research. 217: 77-80. PMID 20965216 DOI: 10.1016/j.bbr.2010.10.009 |
0.532 |
|
| 2011 |
Smith KS, Meloni EG, Myers KM, Van't Veer A, Carlezon WA, Rudolph U. Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice. Psychopharmacology. 213: 697-706. PMID 20922362 DOI: 10.1007/s00213-010-2026-1 |
0.388 |
|
| 2010 |
Butovas S, Rudolph U, Jurd R, Schwarz C, Antkowiak B. Activity patterns in the prefrontal cortex and hippocampus during and after awakening from etomidate anesthesia. Anesthesiology. 113: 48-57. PMID 20508498 DOI: 10.1097/Aln.0B013E3181Dc1Db7 |
0.731 |
|
| 2010 |
Tan KR, Brown M, Labouèbe G, Yvon C, Creton C, Fritschy JM, Rudolph U, Lüscher C. Neural bases for addictive properties of benzodiazepines. Nature. 463: 769-74. PMID 20148031 DOI: 10.1038/Nature08758 |
0.487 |
|
| 2009 |
Li P, Rudolph U, Huntsman MM. Long-term sensory deprivation selectively rearranges functional inhibitory circuits in mouse barrel cortex. Proceedings of the National Academy of Sciences of the United States of America. 106: 12156-61. PMID 19584253 DOI: 10.1073/pnas.0900922106 |
0.472 |
|
| 2009 |
Drexler B, Jurd R, Rudolph U, Antkowiak B. Distinct actions of etomidate and propofol at beta3-containing gamma-aminobutyric acid type A receptors. Neuropharmacology. 57: 446-55. PMID 19555700 DOI: 10.1016/J.Neuropharm.2009.06.014 |
0.769 |
|
| 2009 |
Balic E, Rudolph U, Fritschy JM, Mohler H, Benke D. The alpha5(H105R) mutation impairs alpha5 selective binding properties by altered positioning of the alpha5 subunit in GABAA receptors containing two distinct types of alpha subunits. Journal of Neurochemistry. 110: 244-54. PMID 19457072 DOI: 10.1111/J.1471-4159.2009.06119.X |
0.688 |
|
| 2009 |
Riccio A, Li Y, Moon J, Kim KS, Smith KS, Rudolph U, Gapon S, Yao GL, Tsvetkov E, Rodig SJ, Van't Veer A, Meloni EG, Carlezon WA, Bolshakov VY, Clapham DE. Essential role for TRPC5 in amygdala function and fear-related behavior. Cell. 137: 761-72. PMID 19450521 DOI: 10.1016/J.Cell.2009.03.039 |
0.441 |
|
| 2009 |
Schofield CM, Kleiman-Weiner M, Rudolph U, Huguenard JR. A gain in GABAA receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures. Proceedings of the National Academy of Sciences of the United States of America. 106: 7630-5. PMID 19380748 DOI: 10.1073/pnas.0811326106 |
0.486 |
|
| 2009 |
Zecharia AY, Nelson LE, Gent TC, Schumacher M, Jurd R, Rudolph U, Brickley SG, Maze M, Franks NP. The involvement of hypothalamic sleep pathways in general anesthesia: testing the hypothesis using the GABAA receptor beta3N265M knock-in mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2177-87. PMID 19228970 DOI: 10.1523/JNEUROSCI.4997-08.2009 |
0.739 |
|
| 2009 |
Knabl J, Zeilhofer UB, Crestani F, Rudolph U, Zeilhofer HU. Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice. Pain. 141: 233-8. PMID 19091469 DOI: 10.1016/j.pain.2008.10.015 |
0.47 |
|
| 2009 |
Zarnowska ED, Keist R, Rudolph U, Pearce RA. GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus. Journal of Neurophysiology. 101: 1179-91. PMID 19073796 DOI: 10.1152/Jn.91203.2008 |
0.52 |
|
| 2009 |
Benke D, Barberis A, Kopp S, Altmann KH, Schubiger M, Vogt KE, Rudolph U, Möhler H. GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts. Neuropharmacology. 56: 174-81. PMID 18602406 DOI: 10.1016/J.Neuropharm.2008.06.013 |
0.738 |
|
| 2008 |
Fiorelli R, Rudolph U, Straub CJ, Feldon J, Yee BK. Affective and cognitive effects of global deletion of alpha3-containing gamma-aminobutyric acid-A receptors. Behavioural Pharmacology. 19: 582-96. PMID 18690113 DOI: 10.1097/Fbp.0B013E32830Dc0C7 |
0.488 |
|
| 2008 |
Winsky-Sommerer R, Knapman A, Fedele DE, Schofield CM, Vyazovskiy VV, Rudolph U, Huguenard JR, Fritschy JM, Tobler I. Normal sleep homeostasis and lack of epilepsy phenotype in GABA A receptor alpha3 subunit-knockout mice. Neuroscience. 154: 595-605. PMID 18485607 DOI: 10.1016/J.Neuroscience.2008.03.081 |
0.465 |
|
| 2008 |
Möhler H, Rudolph U, Boison D, Singer P, Feldon J, Yee BK. Regulation of cognition and symptoms of psychosis: focus on GABA(A) receptors and glycine transporter 1. Pharmacology, Biochemistry, and Behavior. 90: 58-64. PMID 18455219 DOI: 10.1016/J.Pbb.2008.03.003 |
0.521 |
|
| 2008 |
Knabl J, Witschi R, Hösl K, Reinold H, Zeilhofer UB, Ahmadi S, Brockhaus J, Sergejeva M, Hess A, Brune K, Fritschy JM, Rudolph U, Möhler H, Zeilhofer HU. Reversal of pathological pain through specific spinal GABAA receptor subtypes. Nature. 451: 330-4. PMID 18202657 DOI: 10.1038/Nature06493 |
0.462 |
|
| 2008 |
Zeller A, Jurd R, Lambert S, Arras M, Drexler B, Grashoff C, Antkowiak B, Rudolph U. Inhibitory ligand-gated ion channels as substrates for general anesthetic actions. Handbook of Experimental Pharmacology. 31-51. PMID 18175085 DOI: 10.1007/978-3-540-74806-9_2 |
0.692 |
|
| 2008 |
Zeller A, Crestani F, Camenisch I, Iwasato T, Itohara S, Fritschy JM, Rudolph U. Cortical glutamatergic neurons mediate the motor sedative action of diazepam. Molecular Pharmacology. 73: 282-91. PMID 17965197 DOI: 10.1124/Mol.107.038828 |
0.43 |
|
| 2008 |
Gerdjikov TV, Rudolph U, Keist R, Möhler H, Feldon J, Yee BK. Hippocampal alpha 5 subunit-containing GABA A receptors are involved in the development of the latent inhibition effect. Neurobiology of Learning and Memory. 89: 87-94. PMID 17638582 DOI: 10.1016/J.Nlm.2007.06.003 |
0.529 |
|
| 2007 |
Grasshoff C, Jurd R, Rudolph U, Antkowiak B. Modulation of presynaptic beta3-containing GABAA receptors limits the immobilizing actions of GABAergic anesthetics. Molecular Pharmacology. 72: 780-7. PMID 17584992 DOI: 10.1124/Mol.107.037648 |
0.752 |
|
| 2007 |
Sanchis-Segura C, Cline B, Jurd R, Rudolph U, Spanagel R. Etomidate and propofol-hyposensitive GABAA receptor beta3(N265M) mice show little changes in acute alcohol sensitivity but enhanced tolerance and withdrawal. Neuroscience Letters. 416: 275-8. PMID 17350761 DOI: 10.1016/J.Neulet.2007.02.024 |
0.698 |
|
| 2007 |
Zeller A, Arras M, Jurd R, Rudolph U. Mapping the contribution of beta3-containing GABAA receptors to volatile and intravenous general anesthetic actions. Bmc Pharmacology. 7: 2. PMID 17319964 DOI: 10.1186/1471-2210-7-2 |
0.725 |
|
| 2007 |
Pangratz-Fuehrer S, Rudolph U, Huguenard JR. Giant spontaneous depolarizing potentials in the developing thalamic reticular nucleus. Journal of Neurophysiology. 97: 2364-72. PMID 17251370 DOI: 10.1152/jn.00646.2006 |
0.505 |
|
| 2007 |
Zeller A, Arras M, Jurd R, Rudolph U. Identification of a molecular target mediating the general anesthetic actions of pentobarbital. Molecular Pharmacology. 71: 852-9. PMID 17164405 DOI: 10.1124/mol.106.030049 |
0.723 |
|
| 2006 |
Grasshoff C, Drexler B, Rudolph U, Antkowiak B. Anaesthetic drugs: linking molecular actions to clinical effects. Current Pharmaceutical Design. 12: 3665-79. PMID 17073666 DOI: 10.2174/138161206778522038 |
0.539 |
|
| 2006 |
Studer R, von Boehmer L, Haenggi T, Schweizer C, Benke D, Rudolph U, Fritschy JM. Alteration of GABAergic synapses and gephyrin clusters in the thalamic reticular nucleus of GABAA receptor alpha3 subunit-null mice. The European Journal of Neuroscience. 24: 1307-15. PMID 16987218 DOI: 10.1111/J.1460-9568.2006.05006.X |
0.466 |
|
| 2006 |
Drexler B, Jurd R, Rudolph U, Antkowiak B. Dual actions of enflurane on postsynaptic currents abolished by the gamma-aminobutyric acid type A receptor beta3(N265M) point mutation. Anesthesiology. 105: 297-304. PMID 16871063 DOI: 10.1097/00000542-200608000-00012 |
0.741 |
|
| 2006 |
Merrill AW, Barter LS, Rudolph U, Eger EI, Antognini JF, Carstens MI, Carstens E. Propofol's effects on nociceptive behavior and spinal c-fos expression after intraplantar formalin injection in mice with a mutation in the gamma-aminobutyric acid-type(A) receptor beta3 subunit. Anesthesia and Analgesia. 103: 478-83, table of con. PMID 16861438 DOI: 10.1213/01.ane.0000223847.50233.1b |
0.384 |
|
| 2006 |
Prenosil GA, Schneider Gasser EM, Rudolph U, Keist R, Fritschy JM, Vogt KE. Specific subtypes of GABAA receptors mediate phasic and tonic forms of inhibition in hippocampal pyramidal neurons. Journal of Neurophysiology. 96: 846-57. PMID 16835366 DOI: 10.1152/JN.01199.2005 |
0.498 |
|
| 2006 |
Sohal VS, Pangratz-Fuehrer S, Rudolph U, Huguenard JR. Intrinsic and synaptic dynamics interact to generate emergent patterns of rhythmic bursting in thalamocortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4247-55. PMID 16624945 DOI: 10.1523/Jneurosci.3812-05.2006 |
0.309 |
|
| 2006 |
Rudolph U, Möhler H. GABA-based therapeutic approaches: GABAA receptor subtype functions. Current Opinion in Pharmacology. 6: 18-23. PMID 16376150 DOI: 10.1016/J.Coph.2005.10.003 |
0.505 |
|
| 2006 |
Drexler B, Grasshoff C, Rudolph U, Unertl K, Antkowiak B. [The GABA(A) receptor family: possibilities for the development of better anesthetics]. Der Anaesthesist. 55: 287-95. PMID 16315024 DOI: 10.1007/S00101-005-0950-Y |
0.512 |
|
| 2005 |
Möhler H, Fritschy JM, Vogt K, Crestani F, Rudolph U. Pathophysiology and pharmacology of GABA(A) receptors. Handbook of Experimental Pharmacology. 225-47. PMID 16594261 DOI: 10.1007/3-540-28082-0-9 |
0.505 |
|
| 2005 |
Grasshoff C, Rudolph U, Antkowiak B. Molecular and systemic mechanisms of general anaesthesia: the 'multi-site and multiple mechanisms' concept. Current Opinion in Anaesthesiology. 18: 386-91. PMID 16534263 DOI: 10.1097/01.Aco.0000174961.90135.Dc |
0.522 |
|
| 2005 |
Yee BK, Keist R, von Boehmer L, Studer R, Benke D, Hagenbuch N, Dong Y, Malenka RC, Fritschy JM, Bluethmann H, Feldon J, Möhler H, Rudolph U. A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction. Proceedings of the National Academy of Sciences of the United States of America. 102: 17154-9. PMID 16284244 DOI: 10.1073/Pnas.0508752102 |
0.734 |
|
| 2005 |
Zeller A, Arras M, Lazaris A, Jurd R, Rudolph U. Distinct molecular targets for the central respiratory and cardiac actions of the general anesthetics etomidate and propofol. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1677-9. PMID 16046472 DOI: 10.1096/fj.04-3443fje |
0.75 |
|
| 2005 |
Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI. Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesthesia and Analgesia. 101: 412-8, table of cont. PMID 16037154 DOI: 10.1213/01.Ane.0000154196.86587.35 |
0.772 |
|
| 2005 |
Liao M, Sonner JM, Husain SS, Miller KW, Jurd R, Rudolph U, Eger EI. R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit. Anesthesia and Analgesia. 101: 131-5, table of cont. PMID 15976219 DOI: 10.1213/01.Ane.0000153011.64764.6F |
0.737 |
|
| 2005 |
Lambert S, Arras M, Vogt KE, Rudolph U. Isoflurane-induced surgical tolerance mediated only in part by beta3-containing GABA(A) receptors. European Journal of Pharmacology. 516: 23-7. PMID 15913600 DOI: 10.1016/j.ejphar.2005.04.030 |
0.543 |
|
| 2005 |
Drexler B, Roether CL, Jurd R, Rudolph U, Antkowiak B. Opposing actions of etomidate on cortical theta oscillations are mediated by different gamma-aminobutyric acid type A receptor subtypes. Anesthesiology. 102: 346-52. PMID 15681950 DOI: 10.1097/00000542-200502000-00017 |
0.73 |
|
| 2005 |
Hauser J, Rudolph U, Keist R, Möhler H, Feldon J, Yee BK. Hippocampal alpha5 subunit-containing GABAA receptors modulate the expression of prepulse inhibition. Molecular Psychiatry. 10: 201-7. PMID 15263904 DOI: 10.1038/Sj.Mp.4001554 |
0.496 |
|
| 2005 |
Zeller A, Arras M, Jurd R, Rudolph U. Distinct molecular targets for the central respiratory and cardiac actions of etomidate and propofol International Congress Series. 1283: 253-255. DOI: 10.1016/j.ics.2005.07.100 |
0.596 |
|
| 2005 |
Jurd R, Arras M, Zeller A, Lambert S, Lazaris A, Crestani F, Drexler B, Siegwart R, Vogt KE, Antkowiak B, Rudolph U. β3-containing GABAA receptors mediate the immobilizing and, in part, the hypnotic actions of etomidate and propofol International Congress Series. 1283: 143-148. DOI: 10.1016/j.ics.2005.07.076 |
0.673 |
|
| 2004 |
Möhler H, Fritschy JM, Crestani F, Hensch T, Rudolph U. Specific GABA(A) circuits in brain development and therapy. Biochemical Pharmacology. 68: 1685-90. PMID 15451412 DOI: 10.1016/j.bcp.2004.07.025 |
0.516 |
|
| 2004 |
Yee BK, Hauser J, Dolgov VV, Keist R, Möhler H, Rudolph U, Feldon J. GABA receptors containing the alpha5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear. The European Journal of Neuroscience. 20: 1928-36. PMID 15380015 DOI: 10.1111/J.1460-9568.2004.03642.X |
0.504 |
|
| 2004 |
Kopp C, Rudolph U, Tobler I. Sleep EEG changes after zolpidem in mice. Neuroreport. 15: 2299-302. PMID 15371753 DOI: 10.1097/00001756-200410050-00031 |
0.355 |
|
| 2004 |
Rudolph U, Antkowiak B. Molecular and neuronal substrates for general anaesthetics. Nature Reviews. Neuroscience. 5: 709-20. PMID 15322529 DOI: 10.1038/Nrn1496 |
0.405 |
|
| 2004 |
Benke D, Fakitsas P, Roggenmoser C, Michel C, Rudolph U, Mohler H. Analysis of the presence and abundance of GABAA receptors containing two different types of alpha subunits in murine brain using point-mutated alpha subunits. The Journal of Biological Chemistry. 279: 43654-60. PMID 15304513 DOI: 10.1074/Jbc.M407154200 |
0.685 |
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| 2004 |
van Rijnsoever C, Täuber M, Choulli MK, Keist R, Rudolph U, Mohler H, Fritschy JM, Crestani F. Requirement of alpha5-GABAA receptors for the development of tolerance to the sedative action of diazepam in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6785-90. PMID 15282283 DOI: 10.1523/Jneurosci.1067-04.2004 |
0.712 |
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| 2004 |
Fagiolini M, Fritschy JM, Löw K, Möhler H, Rudolph U, Hensch TK. Specific GABAA circuits for visual cortical plasticity. Science (New York, N.Y.). 303: 1681-3. PMID 15017002 DOI: 10.1126/Science.1091032 |
0.692 |
|
| 2004 |
Huopaniemi L, Keist R, Randolph A, Certa U, Rudolph U. Diazepam-induced adaptive plasticity revealed by alpha1 GABAA receptor-specific expression profiling. Journal of Neurochemistry. 88: 1059-67. PMID 15009662 DOI: 10.1046/j.1471-4159.2003.02216.x |
0.432 |
|
| 2004 |
Kopp C, Rudolph U, Löw K, Tobler I. Modulation of rhythmic brain activity by diazepam: GABA(A) receptor subtype and state specificity. Proceedings of the National Academy of Sciences of the United States of America. 101: 3674-9. PMID 14990800 DOI: 10.1073/Pnas.0306975101 |
0.49 |
|
| 2004 |
Rudolph U, Möhler H. Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics. Annual Review of Pharmacology and Toxicology. 44: 475-98. PMID 14744255 DOI: 10.1146/Annurev.Pharmtox.44.101802.121429 |
0.529 |
|
| 2004 |
Kosel M, Rudolph U, Wielepp P, Luginbühl M, Schmitt W, Fisch HU, Schlaepfer TE. Diminished GABA(A) receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 347-50. PMID 14628001 DOI: 10.1038/Sj.Npp.1300353 |
0.477 |
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| 2004 |
Kosel M, Rudolph U, Wielepp P, Luginbuhl M, Schmitt W, Fisch HU, Schlaepfer TE. Erratum: Diminished GABAA receptor binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety (Neuropsychopharmacology (2004) 29 (347-350) DOI: 10.1038/sj.npp.1300353) Neuropsychopharmacology. 29. DOI: 10.1038/Sj.Npp.1300447 |
0.303 |
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| 2004 |
van Rijnsoever C, Täuber M, Rudolph U, Fritschy J, Crestani F. P.2.11 Identification of GABAA receptor subtypes involved in tolerance against the sedative action of diazepam European Neuropsychopharmacology. 14: S29. DOI: 10.1016/S0924-977X(04)90034-X |
0.412 |
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| 2004 |
van Rijnsoever C, T↑ber M, Rudolph U, Fritschy J, Crestani F. S.07.02 Identification of GABAA receptor subtypesinvolved in tolerance against the sedative action of diazepam European Neuropsychopharmacology. 14: S124-S125. DOI: 10.1016/S0924-977X(04)80023-3 |
0.311 |
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| 2003 |
Täuber M, Calame-Droz E, Prut L, Rudolph U, Crestani F. alpha2-gamma-Aminobutyric acid (GABA)A receptors are the molecular substrates mediating precipitation of narcosis but not of sedation by the combined use of diazepam and alcohol in vivo. The European Journal of Neuroscience. 18: 2599-604. PMID 14622161 DOI: 10.1046/J.1460-9568.2003.02988.X |
0.463 |
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| 2003 |
Siegwart R, Krähenbühl K, Lambert S, Rudolph U. Mutational analysis of molecular requirements for the actions of general anaesthetics at the gamma-aminobutyric acidA receptor subtype, alpha1beta2gamma2. Bmc Pharmacology. 3: 13. PMID 14613517 DOI: 10.1186/1471-2210-3-13 |
0.541 |
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| 2003 |
Bacci A, Rudolph U, Huguenard JR, Prince DA. Major differences in inhibitory synaptic transmission onto two neocortical interneuron subclasses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9664-74. PMID 14573546 DOI: 10.1523/Jneurosci.23-29-09664.2003 |
0.529 |
|
| 2003 |
Kopp C, Rudolph U, Keist R, Tobler I. Diazepam-induced changes on sleep and the EEG spectrum in mice: role of the alpha3-GABA(A) receptor subtype. The European Journal of Neuroscience. 17: 2226-30. PMID 12786990 DOI: 10.1046/J.1460-9568.2003.02651.X |
0.373 |
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| 2003 |
Sohal VS, Keist R, Rudolph U, Huguenard JR. Dynamic GABA(A) receptor subtype-specific modulation of the synchrony and duration of thalamic oscillations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3649-57. PMID 12736336 DOI: 10.1523/Jneurosci.23-09-03649.2003 |
0.389 |
|
| 2003 |
Jurd R, Arras M, Lambert S, Drexler B, Siegwart R, Crestani F, Zaugg M, Vogt KE, Ledermann B, Antkowiak B, Rudolph U. General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 250-2. PMID 12475885 DOI: 10.1096/Fj.02-0611Fje |
0.769 |
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| 2003 |
Täuber M, Calame-Droz E, Prut L, Rudolph U, Crestani F. α2-γ-Aminobutyric acid (GABA)A receptors are the molecular substrates mediating precipitation of narcosis but not of sedation by the combined use of diazepam and alcohol in vivo European Journal of Neuroscience. 18: 2599-2604. DOI: 10.1046/j.1460-9568.2003.02988.x |
0.333 |
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| 2002 |
Crestani F, Assandri R, Täuber M, Martin JR, Rudolph U. Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists. Neuropharmacology. 43: 679-84. PMID 12367613 DOI: 10.1016/S0028-3908(02)00159-4 |
0.553 |
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| 2002 |
Ohman L, Franzén L, Rudolph U, Birnbaumer L, Hörnquist EH. Regression of Peyer's patches in G alpha i2 deficient mice prior to colitis is associated with reduced expression of Bcl-2 and increased apoptosis. Gut. 51: 392-7. PMID 12171962 DOI: 10.1136/gut.51.3.392 |
0.343 |
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| 2002 |
Crestani F, Keist R, Fritschy JM, Benke D, Vogt K, Prut L, Blüthmann H, Möhler H, Rudolph U. Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 8980-5. PMID 12084936 DOI: 10.1073/Pnas.142288699 |
0.531 |
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| 2002 |
Siegwart R, Jurd R, Rudolph U. Molecular determinants for the action of general anesthetics at recombinant alpha(2)beta(3)gamma(2)gamma-aminobutyric acid(A) receptors. Journal of Neurochemistry. 80: 140-8. PMID 11796752 DOI: 10.1046/j.0022-3042.2001.00682.x |
0.754 |
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| 2002 |
Möhler H, Fritschy JM, Rudolph U. A new benzodiazepine pharmacology. The Journal of Pharmacology and Experimental Therapeutics. 300: 2-8. PMID 11752090 DOI: 10.1124/Jpet.300.1.2 |
0.534 |
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| 2001 |
Rudolph U. Identification of molecular substrate for the attenuation of anxiety: a step toward the development of better anti-anxiety drugs. Thescientificworldjournal. 1: 192-3. PMID 12805666 DOI: 10.1100/tsw.2001.33 |
0.492 |
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| 2001 |
Uhlig HH, Hultgren Hörnquist E, Ohman Bache L, Rudolph U, Birnbaumer L, Mothes T. Antibody response to dietary and autoantigens in G alpha i2-deficient mice. European Journal of Gastroenterology & Hepatology. 13: 1421-9. PMID 11742190 DOI: 10.1097/00042737-200112000-00005 |
0.321 |
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| 2001 |
Möhler H, Crestani F, Rudolph U. GABA(A)-receptor subtypes: a new pharmacology. Current Opinion in Pharmacology. 1: 22-5. PMID 11712530 DOI: 10.1016/S1471-4892(01)00008-X |
0.473 |
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| 2001 |
Crestani F, Möhler H, Rudolph U. Anxiolytic-like action of diazepam: Which GABAA receptor subtype is involved? [1] Trends in Pharmacological Sciences. 22: 402-403. PMID 11515499 DOI: 10.1016/S0165-6147(00)01773-9 |
0.351 |
|
| 2001 |
Tobler I, Kopp C, Deboer T, Rudolph U. Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype. Proceedings of the National Academy of Sciences of the United States of America. 98: 6464-9. PMID 11353839 DOI: 10.1073/Pnas.111055398 |
0.441 |
|
| 2001 |
Rudolph U, Crestani F, Möhler H. GABA(A) receptor subtypes: dissecting their pharmacological functions. Trends in Pharmacological Sciences. 22: 188-94. PMID 11282419 DOI: 10.1016/S0165-6147(00)01646-1 |
0.542 |
|
| 2001 |
Crestani F, Löw K, Keist R, Mandelli M, Möhler H, Rudolph U. Molecular targets for the myorelaxant action of diazepam. Molecular Pharmacology. 59: 442-5. PMID 11179437 DOI: 10.1124/Mol.59.3.442 |
0.504 |
|
| 2001 |
Crestani F, Möhler H, Rudolph U. Anxiolytic-like action of diazepam: mediated by GABAA receptors containing the α2-subunit Trends in Pharmacological Sciences. 22: 403. DOI: 10.1016/S0165-6147(00)01772-7 |
0.667 |
|
| 2000 |
Crestani F, Martin JR, Möhler H, Rudolph U. Mechanism of action of the hypnotic zolpidem in vivo. British Journal of Pharmacology. 131: 1251-4. PMID 11090095 DOI: 10.1038/Sj.Bjp.0703717 |
0.519 |
|
| 2000 |
Crestani F, Martin JR, Möhler H, Rudolph U. Resolving differences in GABAA receptor mutant mouse studies. Nature Neuroscience. 3: 1059. PMID 11036253 DOI: 10.1038/80553 |
0.454 |
|
| 2000 |
Löw K, Crestani F, Keist R, Benke D, Brünig I, Benson JA, Fritschy JM, Rülicke T, Bluethmann H, Möhler H, Rudolph U. Molecular and neuronal substrate for the selective attenuation of anxiety. Science (New York, N.Y.). 290: 131-4. PMID 11021797 DOI: 10.1126/Science.290.5489.131 |
0.47 |
|
| 2000 |
Rudolph U, Crestani F, Benke D, Brünig I, Benson JA, Fritschy J, Martin JR, Bluethmann H, Möhler H. erratum: Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes Nature. 404: 629-629. DOI: 10.1038/35007116 |
0.705 |
|
| 1999 |
Rudolph U, Crestani F, Benke D, Brünig I, Benson JA, Fritschy JM, Martin JR, Bluethmann H, Möhler H. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature. 401: 796-800. PMID 10548105 DOI: 10.1038/44579 |
0.526 |
|
| 1998 |
Benson JA, Löw K, Keist R, Mohler H, Rudolph U. Pharmacology of recombinant gamma-aminobutyric acidA receptors rendered diazepam-insensitive by point-mutated alpha-subunits. Febs Letters. 431: 400-4. PMID 9714551 DOI: 10.1016/S0014-5793(98)00803-5 |
0.737 |
|
| 1998 |
Fritschy JM, Johnson DK, Mohler H, Rudolph U. Independent assembly and subcellular targeting of GABA(A)-receptor subtypes demonstrated in mouse hippocampal and olfactory neurons in vivo. Neuroscience Letters. 249: 99-102. PMID 9682826 DOI: 10.1016/S0304-3940(98)00397-8 |
0.712 |
|
| 1998 |
Mohler H, Luscher B, Fritschy JM, Benke D, Benson J, Rudolph U. GABA(A)-receptor assembly in vivo: lessons from subunit mutant mice. Life Sciences. 62: 1611-5. PMID 9585145 DOI: 10.1016/S0024-3205(98)00116-7 |
0.546 |
|
| 1998 |
Jiang M, Gold MS, Boulay G, Spicher K, Peyton M, Brabet P, Srinivasan Y, Rudolph U, Ellison G, Birnbaumer L. Multiple neurological abnormalities in mice deficient in the G protein Go. Proceedings of the National Academy of Sciences of the United States of America. 95: 3269-74. PMID 9501252 DOI: 10.1073/pnas.95.6.3269 |
0.42 |
|
| 1997 |
Fritschy JM, Benke D, Johnson DK, Mohler H, Rudolph U. GABAA-receptor alpha-subunit is an essential prerequisite for receptor formation in vivo. Neuroscience. 81: 1043-53. PMID 9330366 DOI: 10.1016/S0306-4522(97)00244-3 |
0.486 |
|
| 1996 |
Mohler H, Fritschy JM, Lüscher B, Rudolph U, Benson J, Benke D. The GABAA receptors. From subunits to diverse functions. Ion Channels. 4: 89-113. PMID 8744207 |
0.33 |
|
| 1996 |
Rudolph U, Spicher K, Birnbaumer L. Adenylyl cyclase inhibition and altered G protein subunit expression and ADP-ribosylation patterns in tissues and cells from Gi2 alpha-/-mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 3209-14. PMID 8622915 DOI: 10.1073/Pnas.93.8.3209 |
0.361 |
|
| 1995 |
Rudolph U, Finegold MJ, Rich SS, Harriman GR, Srinivasan Y, Brabet P, Bradley A, Birnbaumer L. Gi2 alpha protein deficiency: a model of inflammatory bowel disease. Journal of Clinical Immunology. 15: 101S-105S. PMID 8613481 DOI: 10.1007/BF01540899 |
0.357 |
|
| 1995 |
Rudolph U, Finegold MJ, Rich SS, Harriman GR, Srinivasan Y, Brabet P, Boulay G, Bradley A, Birnbaumer L. Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice. Nature Genetics. 10: 143-50. PMID 7663509 DOI: 10.1038/ng0695-143 |
0.345 |
|
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