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Geeta Mehta, Ph.D. - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Receptor mediated cell behavior
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kapur A, Mehta P, Simmons AD, Ericksen SS, Mehta G, Palecek SP, Felder M, Stenerson Z, Nayak A, Dominguez JMA, Patankar M, Barroilhet LM. Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers. Cancers. 14. PMID 35565426 DOI: 10.3390/cancers14092297  0.358
2022 Horst EN, Novak CM, Burkhard K, Snyder CS, Verma R, Crochran DE, Geza IA, Fermanich W, Mehta P, Schlautman DC, Tran LA, Brezenger ME, Mehta G. Injectable three-dimensional tumor microenvironments to study mechanobiology in ovarian cancer. Acta Biomaterialia. PMID 35487424 DOI: 10.1016/j.actbio.2022.04.039  0.362
2022 Bregenzer M, Horst E, Mehta P, Snyder C, Repetto T, Mehta G. The Role of the Tumor Microenvironment in CSC Enrichment and Chemoresistance: 3D Co-culture Methods. Methods in Molecular Biology (Clifton, N.J.). 2424: 217-245. PMID 34918298 DOI: 10.1007/978-1-0716-1956-8_15  0.38
2021 Horst EN, Bregenzer ME, Mehta P, Snyder CS, Repetto T, Yang-Hartwich Y, Mehta G. Personalized Models of Heterogenous 3D Epithelial Tumor Microenvironments: Ovarian Cancer as a Model. Acta Biomaterialia. PMID 33940195 DOI: 10.1016/j.actbio.2021.04.041  0.308
2021 Chesnokov MS, Khan I, Park Y, Ezell J, Mehta G, Yousif A, Hong LJ, Buckanovich RJ, Takahashi A, Chefetz I. The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma. Cancers. 13. PMID 33803586 DOI: 10.3390/cancers13061369  0.301
2020 Raghavan S, Snyder CS, Wang A, McLean K, Zamarin D, Buckanovich RJ, Mehta G. Carcinoma-Associated Mesenchymal Stem Cells Promote Chemoresistance in Ovarian Cancer Stem Cells via PDGF Signaling. Cancers. 12. PMID 32726910 DOI: 10.3390/Cancers12082063  0.71
2020 Novak CM, Horst EN, Lin E, Mehta G. Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor. Cancers. 12. PMID 32532057 DOI: 10.3390/Cancers12061521  0.423
2020 Brown JR, Chan DK, Shank JJ, Griffith KA, Fan H, Szulawski R, Yang K, Reynolds RK, Johnston C, McLean K, Uppal S, Liu JR, Cabrera L, Taylor SE, Orr BC, ... ... Mehta G, et al. Phase II clinical trial of metformin as a cancer stem cell-targeting agent in ovarian cancer. Jci Insight. PMID 32369446 DOI: 10.1172/Jci.Insight.133247  0.38
2020 Rivera-Báez L, Lohse I, Lin E, Raghavan S, Owen S, Harouaka R, Herman K, Mehta G, Lawrence TS, Morgan MA, Cuneo KC, Nagrath S. Expansion of Circulating Tumor Cells from Patients with Locally Advanced Pancreatic Cancer Enable Patient Derived Xenografts and Functional Studies for Personalized Medicine. Cancers. 12. PMID 32326109 DOI: 10.3390/Cancers12041011  0.715
2020 Raghavan S, Mehta P, Xie Y, Lei YL, Mehta G. Abstract B07: Ovarian cancer stem-like cells and alternately activated macrophages reciprocally interact through the WNT pathway to promote protumoral and malignant phenotypes in 3D engineered microenvironments Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-B07  0.399
2020 Mehta P, Bregenzer M, Rashidi MW, Raghavan S, Fleck E, Horst E, Harissa Z, Ravikumar V, Brady S, Bild A, Rao A, Buckanovich R, Mehta G. Abstract A52: Serially passaging ovarian cancer spheroids as an in situ model for emergence of chemoresistance and enrichment of cancer stem cells Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-A52  0.451
2020 Kapur A, Kajla M, Paskewitz S, Cappuccini A, Mehta P, Mehta G, Patankar M. Abstract A16: A novel death receptor ligand fabclavine inhibits cancer and cancer stem cell proliferation by extrinsic apoptosis Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-A16  0.456
2019 Bregenzer ME, Horst EN, Mehta P, Novak CM, Repetto T, Snyder CS, Mehta G. Tumor modeling maintains diverse pathology . Annals of Translational Medicine. 7: S262. PMID 32015981 DOI: 10.21037/Atm.2019.12.32  0.347
2019 Bregenzer ME, Davis C, Horst EN, Mehta P, Novak CM, Raghavan S, Snyder CS, Mehta G. Physiologic Patient Derived 3D Spheroids for Anti-neoplastic Drug Screening to Target Cancer Stem Cells. Journal of Visualized Experiments : Jove. PMID 31329171 DOI: 10.3791/59696  0.727
2019 Raghavan S, Mehta P, Xie Y, Lei YL, Mehta G. Ovarian cancer stem cells and macrophages reciprocally interact through the WNT pathway to promote pro-tumoral and malignant phenotypes in 3D engineered microenvironments. Journal For Immunotherapy of Cancer. 7: 190. PMID 31324218 DOI: 10.1186/S40425-019-0666-1  0.716
2019 Bregenzer ME, Horst EN, Mehta P, Novak CM, Repetto T, Mehta G. The Role of Cancer Stem Cells and Mechanical Forces in Ovarian Cancer Metastasis. Cancers. 11. PMID 31323899 DOI: 10.3390/Cancers11071008  0.432
2019 Novak C, Horst E, Taylor C, Liu C, Mehta G. Fluid shear stress stimulates breast cancer cells to display invasive and chemoresistant phenotypes while upregulating PLAU in a 3D bioreactor. Biotechnology and Bioengineering. PMID 31317530 DOI: 10.1002/Bit.27119  0.347
2019 Ward Rashidi MR, Mehta P, Bregenzer M, Raghavan S, Fleck EM, Horst EN, Harissa Z, Ravikumar V, Brady S, Bild A, Rao A, Buckanovich RJ, Mehta G. Engineered 3D Model of Cancer Stem Cell Enrichment and Chemoresistance. Neoplasia (New York, N.Y.). 21: 822-836. PMID 31299607 DOI: 10.1016/J.Neo.2019.06.005  0.727
2019 LaLone V, Fawaz MV, Morales-Mercado J, Mourão MA, Snyder CS, Kim SY, Lieberman AP, Tuteja A, Mehta G, Standiford TJ, Raghavendran K, Shedden K, Schwendeman A, Stringer KA, Rosania GR. Inkjet-printed micro-calibration standards for ultraquantitative Raman spectral cytometry. The Analyst. PMID 31116195 DOI: 10.1039/C9An00500E  0.353
2019 Bregenzer ME, Horst EN, Mehta P, Novak CM, Raghavan S, Snyder CS, Mehta G. Integrated cancer tissue engineering models for precision medicine. Plos One. 14: e0216564. PMID 31075118 DOI: 10.1371/Journal.Pone.0216564  0.717
2019 Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, ... ... Mehta G, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Reports. 26: 3061-3075.e6. PMID 30865894 DOI: 10.1016/J.Celrep.2019.02.032  0.368
2019 Novak C, Horst E, Davis C, Mehta G. Abstract TMIM-080: MECHANOTRANSDUCTION IN OVARIAN CANCERS Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Tmim-080  0.432
2018 Mehta P, Novak C, Raghavan S, Ward M, Mehta G. Self-Renewal and CSCs In Vitro Enrichment: Growth as Floating Spheres. Methods in Molecular Biology (Clifton, N.J.). 1692: 61-75. PMID 28986887 DOI: 10.1007/978-1-4939-7401-6_6  0.737
2018 Raghavan S, Mehta P, Bregenzer M, Rashidi MW, Fleck E, Tan L, McLean K, Buckanovich R, Mehta G. Abstract A33: Patient-specific evaluation of chemoresistance and tumor recurrence using ovarian cancer stem cell spheroids Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Ovca17-A33  0.386
2018 Novak C, Horst E, Raghavan S, Mehta G. Abstract 187: Breast cancer cells exhibit enhanced proliferation, invasion, PLAU expression and chemoresistance when exposed to fluid shear stress in an innovative 3D bioreactor Tumor Biology. DOI: 10.1158/1538-7445.Am2018-187  0.328
2018 Raghavan S, Mehta G. Abstract 118: Immuno-modulation of macrophages by ovarian cancer stem cells in an in vitro 3D spheroid platform Cancer Research. 78: 118-118. DOI: 10.1158/1538-7445.Am2018-118  0.359
2017 Chien J, Mehta G. Meeting Report From the 2016 11th Biennial Ovarian Cancer Research Symposium: Mechanisms of Initiation and Progression of Ovarian Cancers. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 27: S10-S13. PMID 29278599 DOI: 10.1097/Igc.0000000000001117  0.354
2017 McLean K, Mehta G. Tumor Microenvironment and Models of Ovarian Cancer: The 11th Biennial Rivkin Center Ovarian Cancer Research Symposium. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. PMID 29049091 DOI: 10.1097/Igc.0000000000001119  0.394
2017 Shalev O, Raghavan S, Mazzara JM, Senabulya N, Sinko PD, Fleck E, Rockwell C, Simopoulos N, Jones CM, Schwendeman A, Mehta G, Clarke R, Amidon GE, Shtein M. Printing of small molecular medicines from the vapor phase. Nature Communications. 8: 711. PMID 28955031 DOI: 10.1038/S41467-017-00763-6  0.671
2017 Raghavan S, Mehta P, Ward MW, Bregenzer ME, Fleck EMA, Tan L, McLean K, Buckanovich R, Mehta G. Personalized Medicine Based Approach to Model Patterns of Chemoresistance and Tumor Recurrence Using Ovarian Cancer Stem Cell Spheroids. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28814433 DOI: 10.1158/1078-0432.Ccr-17-0133  0.721
2017 Buckanovich RJ, Brown J, Shank J, Griffith KA, Reynolds RK, Johnston C, McLean K, Uppal S, Liu JR, Cabrera L, Mehta G. A phase II clinical trial of metformin as a cancer stem cell targeting agent in stage IIc/III/IV ovarian, fallopian tube, and primary peritoneal cancer. Journal of Clinical Oncology. 35: 5556-5556. DOI: 10.1200/Jco.2017.35.15_Suppl.5556  0.361
2017 Raghavan S, Ward M, Mehta P, Buckanovich RJ, Mehta G. Abstract AP22: CHEMORESISTANCE, TUMOR INITIATION AND TUMOR RE–EMERGENCE TRENDS IN MALIGNANT ASCITES–DERIVED OVARIAN CANCER STEM CELL SPHEROIDS Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap22  0.473
2016 Raghavan S, Mehta P, Horst EN, Ward MR, Rowley KR, Mehta G. Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity. Oncotarget. PMID 26918944 DOI: 10.18632/Oncotarget.7659  0.716
2015 Raghavan S, Ward MR, Rowley KR, Wold RM, Takayama S, Buckanovich RJ, Mehta G. Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays. Gynecologic Oncology. 138: 181-9. PMID 25913133 DOI: 10.1016/J.Ygyno.2015.04.014  0.757
2015 Raghavan S, Ward MR, Rowley KR, Wold RM, Takayama S, Buckanovich RJ, Mehta G. Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays Gynecologic Oncology. 138: 181-189. DOI: 10.1016/j.ygyno.2015.04.014  0.509
2014 Dixon AR, Rajan S, Kuo CH, Bersano T, Wold R, Futai N, Takayama S, Mehta G. Microfluidic device capable of medium recirculation for non-adherent cell culture. Biomicrofluidics. 8: 016503. PMID 24753733 DOI: 10.1063/1.4865855  0.536
2012 Mehta G, Hsiao AY, Ingram M, Luker GD, Takayama S. Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 192-204. PMID 22613880 DOI: 10.1016/J.Jconrel.2012.04.045  0.525
2012 Moraes C, Mehta G, Lesher-Perez SC, Takayama S. Organs-on-a-chip: a focus on compartmentalized microdevices. Annals of Biomedical Engineering. 40: 1211-27. PMID 22065201 DOI: 10.1007/S10439-011-0455-6  0.482
2011 Didwania M, Didwania A, Mehta G, Basak GW, Yasukawa S, Takayama S, de Necochea-Campion R, Srivastava A, Carrier E. Artificial hematopoietic stem cell niche: bioscaffolds to microfluidics to mathematical simulations. Current Topics in Medicinal Chemistry. 11: 1599-605. PMID 21446910 DOI: 10.2174/156802611796117568  0.531
2011 Williams CM, Mehta G, Peyton SR, Zeiger AS, Van Vliet KJ, Griffith LG. Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays. Tissue Engineering. Part A. 17: 1055-68. PMID 21121876 DOI: 10.1089/Ten.Tea.2010.0398  0.305
2009 Mehta K, Mehta G, Takayama S, Linderman J. Quantitative inference of cellular parameters from microfluidic cell culture systems Biotechnology and Bioengineering. 103: 966-974. PMID 19388086 DOI: 10.1002/Bit.22334  0.765
2009 Mehta G, Lee J, Cha W, Tung YC, Linderman JJ, Takayama S. Hard top soft bottom microfluidic devices for cell culture and chemical analysis. Analytical Chemistry. 81: 3714-22. PMID 19382754 DOI: 10.1021/Ac802178U  0.633
2007 Mehta G, Mehta K, Sud D, Song JW, Bersano-Begey T, Futai N, Heo YS, Mycek MA, Linderman JJ, Takayama S. Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture. Biomedical Microdevices. 9: 123-34. PMID 17160707 DOI: 10.1007/S10544-006-9005-7  0.76
2007 Mehta G, Kiel MJ, Lee JW, Kotov N, Linderman JJ, Takayama S. Polyelectrolyte-clay-protein layer films on microfluidic PDMS bioreactor surfaces for primary murine bone marrow culture** Advanced Functional Materials. 17: 2701-2709. DOI: 10.1002/Adfm.200700016  0.628
2006 Sud D, Mehta G, Mehta K, Linderman J, Takayama S, Mycek MA. Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture Journal of Biomedical Optics. 11. PMID 17092147 DOI: 10.1117/1.2355665  0.755
2006 Sud D, Mehta G, Mehta K, Linderman J, Takayama S, Mycek MA. Fluorescence lifetime imaging microscopy (FLIM) measures oxygen gradients in microfluidic bioreactors Optics Infobase Conference Papers. DOI: 10.1364/Bio.2006.Tui52  0.745
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