Lauren C. Purington, Ph.D. - Publications

University of Michigan, Ann Arbor, Ann Arbor, MI 
Opiod signal transductions, addiction

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Moynihan HA, Derrick I, Broadbear JH, Greedy BM, Aceto MD, Harris LS, Purington LC, Thomas MP, Woods JH, Traynor JR, Husbands SM, Lewis JW. Fumaroylamino-4,5-epoxymorphinans and related opioids with irreversible μ opioid receptor antagonist effects. Journal of Medicinal Chemistry. 55: 9868-74. PMID 23043264 DOI: 10.1021/jm301096s  0.84
2012 Anand JP, Purington LC, Pogozheva ID, Traynor JR, Mosberg HI. Modulation of opioid receptor ligand affinity and efficacy using active and inactive state receptor models. Chemical Biology & Drug Design. 80: 763-70. PMID 22882801 DOI: 10.1111/cbdd.12014  0.84
2011 Purington LC, Sobczyk-Kojiro K, Pogozheva ID, Traynor JR, Mosberg HI. Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide. Acs Chemical Biology. 6: 1375-81. PMID 21958158 DOI: 10.1021/cb200263q  0.84
2011 Levitt ES, Purington LC, Traynor JR. Gi/o-coupled receptors compete for signaling to adenylyl cyclase in SH-SY5Y cells and reduce opioid-mediated cAMP overshoot. Molecular Pharmacology. 79: 461-71. PMID 21098043 DOI: 10.1124/mol.110.064816  0.84
2009 Nieland NP, Rennison D, Broadbear JH, Purington L, Woods JH, Traynor JR, Lewis JW, Husbands SM. 14beta-Arylpropiolylamino-17-cyclopropylmethyl-7,8-dihydronormorphinones and related opioids. Further examples of pseudoirreversible mu opioid receptor antagonists. Journal of Medicinal Chemistry. 52: 6926-30. PMID 19842669 DOI: 10.1021/jm901074a  0.84
2009 Purington LC, Pogozheva ID, Traynor JR, Mosberg HI. Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist properties. Journal of Medicinal Chemistry. 52: 7724-31. PMID 19788201 DOI: 10.1021/jm9007483  0.84
2009 Moynihan H, Jales AR, Greedy BM, Rennison D, Broadbear JH, Purington L, Traynor JR, Woods JH, Lewis JW, Husbands SM. 14 beta-O-cinnamoylnaltrexone and related dihydrocodeinones are mu opioid receptor partial agonists with predominant antagonist activity. Journal of Medicinal Chemistry. 52: 1553-7. PMID 19253983 DOI: 10.1021/jm8012272  0.84
2009 Cami-Kobeci G, Neal AP, Bradbury FA, Purington LC, Aceto MD, Harris LS, Lewis JW, Traynor JR, Husbands SM. Mixed kappa/mu opioid receptor agonists: the 6 beta-naltrexamines. Journal of Medicinal Chemistry. 52: 1546-52. PMID 19253970 DOI: 10.1021/jm8015552  0.84
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