Tija Jacob - Publications

Neurobiology University of Pennsylvania, Philadelphia, PA, United States 
 Neuroscience Tufts University Sackler School of Biomedical Research 
 Pharmacology University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 
GABA A receptor trafficking, circuit development

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lorenz-Guertin JM, Povysheva N, Chapman CA, MacDonald ML, Fazzari M, Nigam A, Nuwer JL, Das S, Brady ML, Vajn K, Bambino MJ, Weintraub ST, Johnson JW, Jacob TC. Inhibitory and excitatory synaptic neuroadaptations in the diazepam tolerant brain. Neurobiology of Disease. 106248. PMID 37536384 DOI: 10.1016/j.nbd.2023.106248  0.45
2023 Nuwer JL, Povysheva N, Jacob TC. Long-term α5 GABA A receptor negative allosteric modulator treatment reduces NMDAR-mediated neuronal excitation and maintains basal neuronal inhibition. Neuropharmacology. 237: 109587. PMID 37270156 DOI: 10.1016/j.neuropharm.2023.109587  0.377
2022 Chapman CA, Nuwer JL, Jacob TC. The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms. Frontiers in Synaptic Neuroscience. 14: 911020. PMID 35663370 DOI: 10.3389/fnsyn.2022.911020  0.415
2021 Nuwer JL, Brady ML, Povysheva NV, Coyne A, Jacob TC. Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission. Neuropharmacology. 108724. PMID 34284042 DOI: 10.1016/j.neuropharm.2021.108724  0.392
2020 Lombardi JP, Kinzlmaier DA, Jacob TC. Visualizing GABA A Receptor Trafficking Dynamics with Fluorogenic Protein Labeling. Current Protocols in Neuroscience. 92: e97. PMID 32364672 DOI: 10.1002/cpns.97  0.425
2019 Jacob TC. Neurobiology and Therapeutic Potential of α5-GABA Type A Receptors. Frontiers in Molecular Neuroscience. 12: 179. PMID 31396049 DOI: 10.3389/fnmol.2019.00179  0.412
2019 Lorenz-Guertin JM, Bambino MJ, Das S, Weintraub ST, Jacob TC. Diazepam Accelerates GABAR Synaptic Exchange and Alters Intracellular Trafficking. Frontiers in Cellular Neuroscience. 13: 163. PMID 31080408 DOI: 10.3389/fncel.2019.00163  0.485
2017 Brady ML, Pilli J, Lorenz-Guertin JM, Das S, Moon CE, Graff N, Jacob TC. Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. PMID 29074304 DOI: 10.1016/j.neuropharm.2017.10.022  0.516
2017 Lorenz-Guertin JM, Wilcox MR, Zhang M, Larsen MB, Pilli J, Schmidt BF, Bruchez MP, Johnson JW, Waggoner AS, Watkins SC, Jacob TC. A versatile optical tool for studying synaptic GABAA receptor trafficking. Journal of Cell Science. PMID 29025969 DOI: 10.1242/Jcs.205286  0.39
2017 Lorenz-Guertin JM, Jacob TC. GABA type A receptor trafficking and the architecture of synaptic inhibition. Developmental Neurobiology. PMID 28901728 DOI: 10.1002/dneu.22536  0.506
2015 Brady ML, Jacob TC. Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation. Developmental Neurobiology. PMID 25663431 DOI: 10.1002/dneu.22280  0.425
2014 Petrini EM, Ravasenga T, Hausrat TJ, Iurilli G, Olcese U, Racine V, Sibarita JB, Jacob TC, Moss SJ, Benfenati F, Medini P, Kneussel M, Barberis A. Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP. Nature Communications. 5: 3921. PMID 24894704 DOI: 10.1038/Ncomms4921  0.68
2014 Brady ML, Moon CE, Jacob TC. Using an α-bungarotoxin binding site tag to study GABA A receptor membrane localization and trafficking. Journal of Visualized Experiments : Jove. PMID 24747556 DOI: 10.3791/51365  0.374
2012 Jacob TC, Michels G, Silayeva L, Haydon J, Succol F, Moss SJ. Benzodiazepine treatment induces subtype-specific changes in GABA(A) receptor trafficking and decreases synaptic inhibition. Proceedings of the National Academy of Sciences of the United States of America. 109: 18595-600. PMID 23091016 DOI: 10.1073/pnas.1204994109  0.712
2009 Jacob TC, Wan Q, Vithlani M, Saliba RS, Succol F, Pangalos MN, Moss SJ. GABA(A) receptor membrane trafficking regulates spine maturity. Proceedings of the National Academy of Sciences of the United States of America. 106: 12500-5. PMID 19617557 DOI: 10.1073/pnas.0903943106  0.688
2008 Jacob TC, Moss SJ, Jurd R. GABA(A) receptor trafficking and its role in the dynamic modulation of neuronal inhibition. Nature Reviews. Neuroscience. 9: 331-43. PMID 18382465 DOI: 10.1038/nrn2370  0.751
2008 Tretter V, Jacob TC, Mukherjee J, Fritschy JM, Pangalos MN, Moss SJ. The clustering of GABA(A) receptor subtypes at inhibitory synapses is facilitated via the direct binding of receptor alpha 2 subunits to gephyrin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1356-65. PMID 18256255 DOI: 10.1523/Jneurosci.5050-07.2008  0.737
2007 Saliba RS, Michels G, Jacob TC, Pangalos MN, Moss SJ. Activity-dependent ubiquitination of GABA(A) receptors regulates their accumulation at synaptic sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13341-51. PMID 18045928 DOI: 10.1523/JNEUROSCI.3277-07.2007  0.76
2005 Jacob TC, Bogdanov YD, Magnus C, Saliba RS, Kittler JT, Haydon PG, Moss SJ. Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10469-78. PMID 16280585 DOI: 10.1523/JNEUROSCI.2267-05.2005  0.725
2003 Jacob TC, Kaplan JM. The EGL-21 carboxypeptidase E facilitates acetylcholine release at Caenorhabditis elegans neuromuscular junctions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2122-30. PMID 12657671 DOI: 10.1523/Jneurosci.23-06-02122.2003  0.429
2001 Kass J, Jacob TC, Kim P, Kaplan JM. The EGL-3 proprotein convertase regulates mechanosensory responses of Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9265-72. PMID 11717360 DOI: 10.1523/Jneurosci.21-23-09265.2001  0.619
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