Jack W. Pike, Ph.D. - Publications

Affiliations: 
Biological Sciences University of Delaware, Newark, DE, United States 
Area:
Behavioral Neuroendocrinology and Field Endocrinology

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 MacLeod RS, Meyer MB, Xiong J, Cawley KM, Liu Y, Onal M, Benkusky NA, Thostenson JD, Pike JW, O'Brien CA. Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo. Plos One. 16: e0250974. PMID 33970941 DOI: 10.1371/journal.pone.0250974  0.306
2021 Pike JW, Lee SM, Benkusky NA, Meyer MB. Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism. Jbmr Plus. 5: e10433. PMID 33553989 DOI: 10.1002/jbm4.10433  0.418
2021 Oda Y, Wong C, Oh D, Meyer M, Pike J, Bikle D. 175 Dynamic transcriptional and epigenetic regulation through vitamin D receptor and p63/p53 signaling in epidermal keratinocytes Journal of Investigative Dermatology. 141: S31. DOI: 10.1016/J.JID.2021.02.195  0.345
2019 Meyer MB, Pike JW. Mechanistic homeostasis of vitamin D metabolism in the kidney through reciprocal modulation of Cyp27b1 and Cyp24a1 expression. The Journal of Steroid Biochemistry and Molecular Biology. 196: 105500. PMID 31629064 DOI: 10.1016/j.jsbmb.2019.105500  0.418
2019 Lee SM, Carlson AH, Onal M, Benkusky NA, Meyer MB, Pike JW. A control region near the fibroblast growth factor 23 gene mediates response to phosphate, 1,25(OH)2D3 and LPS in vivo. Endocrinology. PMID 31599948 DOI: 10.1210/en.2019-00622  0.32
2019 Meyer MB, Lee SM, Carlson AH, Benkusky NA, Kaufmann M, Jones G, Pike JW. A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene in renal and non-renal tissues. The Journal of Biological Chemistry. PMID 31439663 DOI: 10.1074/jbc.RA119.010173  0.352
2019 Meyer MB, Benkusky NA, Kaufmann M, Lee SM, Redfield RR, Jones G, Pike JW. Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient pseudo-null mouse. The Journal of Biological Chemistry. PMID 31053643 DOI: 10.1074/jbc.RA119.008760  0.445
2017 Pike JW, Christakos S. Biology and Mechanisms of Action of the Vitamin D Hormone. Endocrinology and Metabolism Clinics of North America. 46: 815-843. PMID 29080638 DOI: 10.1016/j.ecl.2017.07.001  0.456
2017 Meyer MB, Benkusky NA, Kaufmann M, Lee SM, Onal M, Jones G, Pike JW. A Kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation. The Journal of Biological Chemistry. PMID 28808057 DOI: 10.1074/jbc.M117.806901  0.446
2017 Lee SM, Meyer MB, Benkusky NA, O'Brien CA, Pike JW. The impact of VDR expression and regulation in vivo. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28602960 DOI: 10.1016/j.jsbmb.2017.06.002  0.399
2017 Shamsuzzaman S, Onal M, John HCS, Pike JW. Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice. Journal of Cellular Biochemistry. PMID 28419519 DOI: 10.1002/jcb.26074  0.3
2017 Pike JW, Meyer MB, Lee SM, Onal M, Benkusky NA. The vitamin D receptor: contemporary genomic approaches reveal new basic and translational insights. The Journal of Clinical Investigation. PMID 28240603 DOI: 10.1172/JCI88887  0.496
2017 Ryynänen J, Kriebitzsch C, Meyer MB, Janssens I, Pike JW, Verlinden L, Verstuyf A. Class 3 semaphorins are transcriptionally regulated by 1,25(OH)2D3 in osteoblasts. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28189595 DOI: 10.1016/j.jsbmb.2017.02.005  0.476
2016 Shamsuzzaman S, Onal M, St John HC, Jeffery JJ, Pike JW. Absence of the Vitamin D Receptor Inhibits Atherosclerotic Plaque Calcification in Female Hypercholesterolemic Mice. Journal of Cellular Biochemistry. PMID 27567005 DOI: 10.1002/jcb.25679  0.333
2016 Rodriguez GC, Turbov J, Rosales R, Yoo J, Hunn J, Zappia KJ, Lund K, Barry CP, Rodriguez IV, Pike JW, Conrads TP, Darcy KM, Maxwell GL, Hamilton CA, Syed V, et al. Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention. Gynecologic Oncology. PMID 27106018 DOI: 10.1016/j.ygyno.2016.04.022  0.431
2016 Pike JW, Meyer MB, Benkusky NA, Lee SM, St John H, Carlson A, Onal M, Shamsuzzaman S. Genomic Determinants of Vitamin D-Regulated Gene Expression. Vitamins and Hormones. 100: 21-44. PMID 26827947 DOI: 10.1016/bs.vh.2015.10.011  0.451
2015 Onal M, St John HC, Danielson AL, Markert JW, Riley EM, Pike JW. Unique Distal Enhancers Linked to the Mouse Tnfsf11 Gene Direct Tissue-Specific and Inflammation-induced Expression of RANKL. Endocrinology. en20151788. PMID 26646205 DOI: 10.1210/en.2015-1788  0.413
2015 Lee SM, Meyer MB, Benkusky NA, O'Brien CA, Pike JW. Mechanisms of Enhancer-mediated Hormonal Control of Vitamin D Receptor Gene Expression in Target Cells. The Journal of Biological Chemistry. PMID 26504088 DOI: 10.1074/jbc.M115.693614  0.47
2015 Kaufmann M, Min Lee S, Pike JW, Jones G. A High-calcium and Phosphate Rescue Diet and VDR-expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice. Endocrinology. en20151664. PMID 26441239 DOI: 10.1210/en.2015-1664  0.311
2015 St John HC, Hansen SJ, Pike JW. Analysis of SOST expression using large minigenes reveals the MEF2C binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFβ1 responsiveness. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26361013 DOI: 10.1016/j.jsbmb.2015.09.005  0.353
2015 Onal M, St John HC, Danielson AL, Pike JW. Deletion of the Distal Tnfsf11 RL-D2 Enhancer that Contributes to PTH-Mediated RANKL Expression in Osteoblast Lineage Cells Results in a High Bone Mass Phenotype in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26332516 DOI: 10.1002/jbmr.2698  0.442
2015 Lee SM, Pike JW. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26323657 DOI: 10.1016/j.jsbmb.2015.08.018  0.453
2015 Kaneko I, Sabir MS, Dussik CM, Whitfield GK, Karrys A, Hsieh JC, Haussler MR, Meyer MB, Pike JW, Jurutka PW. 1,25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26071405 DOI: 10.1096/Fj.14-269811  0.486
2015 Lee SM, Riley EM, Meyer MB, Benkusky NA, Plum LA, DeLuca HF, Pike JW. 1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components. The Journal of Biological Chemistry. 290: 18199-215. PMID 26041780 DOI: 10.1074/Jbc.M115.665794  0.454
2015 Pike JW, Meyer MB, St John HC, Benkusky NA. Epigenetic histone modifications and master regulators as determinants of context dependent nuclear receptor activity in bone cells. Bone. PMID 25819039 DOI: 10.1016/j.bone.2015.03.012  0.329
2015 Meyer MB, Benkusky NA, Pike JW. Selective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions. The Journal of Biological Chemistry. 290: 11093-107. PMID 25773540 DOI: 10.1074/jbc.M115.648394  0.342
2015 St John HC, Meyer MB, Benkusky NA, Carlson AH, Prideaux M, Bonewald LF, Pike JW. The parathyroid hormone-regulated transcriptome in osteocytes: parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function. Bone. 72: 81-91. PMID 25460572 DOI: 10.1016/J.Bone.2014.11.010  0.415
2015 Lee SM, Pike JW. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3 Journal of Steroid Biochemistry and Molecular Biology. DOI: 10.1016/j.jsbmb.2015.08.018  0.48
2014 Pike JW. Expression of the vitamin D receptor in skeletal muscle: are we there yet? Endocrinology. 155: 3214-8. PMID 25152176 DOI: 10.1210/en.2014-1624  0.361
2014 Lee SM, Goellner JJ, O'Brien CA, Pike JW. A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia. Endocrinology. 155: 4137-48. PMID 25147982 DOI: 10.1210/en.2014-1417  0.397
2014 Meyer MB, Benkusky NA, Lee CH, Pike JW. Genomic determinants of gene regulation by 1,25-dihydroxyvitamin D3 during osteoblast-lineage cell differentiation. The Journal of Biological Chemistry. 289: 19539-54. PMID 24891508 DOI: 10.1074/jbc.M114.578104  0.46
2014 St John HC, Bishop KA, Meyer MB, Benkusky NA, Leng N, Kendziorski C, Bonewald LF, Pike JW. The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone. Molecular Endocrinology (Baltimore, Md.). 28: 1150-65. PMID 24877565 DOI: 10.1210/Me.2014-1091  0.416
2014 Lee SM, Bishop KA, Goellner JJ, O'Brien CA, Pike JW. Mouse and human BAC transgenes recapitulate tissue-specific expression of the vitamin D receptor in mice and rescue the VDR-null phenotype. Endocrinology. 155: 2064-76. PMID 24693968 DOI: 10.1210/en.2014-1107  0.428
2014 Pike JW, Lee SM, Meyer MB. Regulation of gene expression by 1,25-dihydroxyvitamin D3 in bone cells: exploiting new approaches and defining new mechanisms. Bonekey Reports. 3: 482. PMID 24466413 DOI: 10.1038/bonekey.2013.216  0.438
2014 Pike JW, Meyer MB. Fundamentals of vitamin D hormone-regulated gene expression. The Journal of Steroid Biochemistry and Molecular Biology. 144: 5-11. PMID 24239506 DOI: 10.1016/j.jsbmb.2013.11.004  0.447
2014 Meyer MB, Benkusky NA, Pike JW. 1,25-Dihydroxyvitamin D3 induced histone profiles guide discovery of VDR action sites. The Journal of Steroid Biochemistry and Molecular Biology. 144: 19-21. PMID 24041718 DOI: 10.1016/j.jsbmb.2013.09.005  0.337
2013 Eelen G, Verlinden L, Meyer MB, Gijsbers R, Pike JW, Bouillon R, Verstuyf A. 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts. The Journal of Steroid Biochemistry and Molecular Biology. 136: 112-9. PMID 22989484 DOI: 10.1016/j.jsbmb.2012.09.011  0.444
2013 Meyer MB, Pike JW. Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes. The Journal of Steroid Biochemistry and Molecular Biology. 136: 120-4. PMID 22944139 DOI: 10.1016/j.jsbmb.2012.08.006  0.471
2012 Pike JW, Meyer MB. The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D3. Rheumatic Diseases Clinics of North America. 38: 13-27. PMID 22525840 DOI: 10.1016/j.rdc.2012.03.004  0.392
2012 Pike JW, Meyer MB. Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D(3) action. Archives of Biochemistry and Biophysics. 523: 2-8. PMID 22179019 DOI: 10.1016/j.abb.2011.12.003  0.482
2012 Meyer MB, Goetsch PD, Pike JW. VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression. Molecular Endocrinology (Baltimore, Md.). 26: 37-51. PMID 22108803 DOI: 10.1210/me.2011-1109  0.403
2012 Pike JW, Meyer MB, Bishop KA. Regulation of target gene expression by the vitamin D receptor - an update on mechanisms. Reviews in Endocrine & Metabolic Disorders. 13: 45-55. PMID 21870057 DOI: 10.1007/s11154-011-9198-9  0.499
2011 Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A. 1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2991-3000. PMID 21898591 DOI: 10.1002/Jbmr.493  0.482
2011 Hidalgo AA, Deeb KK, Pike JW, Johnson CS, Trump DL. Dexamethasone enhances 1alpha,25-dihydroxyvitamin D3 effects by increasing vitamin D receptor transcription. The Journal of Biological Chemistry. 286: 36228-37. PMID 21868377 DOI: 10.1074/Jbc.M111.244061  0.451
2011 Pike JW. Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand. Molecular and Cellular Endocrinology. 347: 3-10. PMID 21664239 DOI: 10.1016/j.mce.2011.05.012  0.496
2011 Bishop KA, Coy HM, Nerenz RD, Meyer MB, Pike JW. Mouse Rankl expression is regulated in T cells by c-Fos through a cluster of distal regulatory enhancers designated the T cell control region. The Journal of Biological Chemistry. 286: 20880-91. PMID 21487009 DOI: 10.1074/jbc.M111.231548  0.338
2011 Martowicz ML, Meyer MB, Pike JW. The mouse RANKL gene locus is defined by a broad pattern of histone H4 acetylation and regulated through distinct distal enhancers. Journal of Cellular Biochemistry. 112: 2030-45. PMID 21465526 DOI: 10.1002/Jcb.23123  0.408
2011 Pike JW, Meyer MB, Lee SM. The vitamin D receptor: Biochemical, molecular, biological, and genomic era investigations Vitamin D. 97-135. DOI: 10.1016/B978-0-12-381978-9.10007-1  0.385
2011 Feldman JD, Pike JW, Adams JS. Vitamin D Vitamin D 0.397
2010 Pike JW, Meyer MB. The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D(3). Endocrinology and Metabolism Clinics of North America. 39: 255-69, table of con. PMID 20511050 DOI: 10.1016/j.ecl.2010.02.007  0.484
2010 Ajibade DV, Dhawan P, Fechner AJ, Meyer MB, Pike JW, Christakos S. Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactin. Endocrinology. 151: 2974-84. PMID 20463051 DOI: 10.1210/en.2010-0033  0.443
2010 Chun RF, Lauridsen AL, Suon L, Zella LA, Pike JW, Modlin RL, Martineau AR, Wilkinson RJ, Adams J, Hewison M. Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. The Journal of Clinical Endocrinology and Metabolism. 95: 3368-76. PMID 20427486 DOI: 10.1210/Jc.2010-0195  0.429
2010 Meyer MB, Goetsch PD, Pike JW. A downstream intergenic cluster of regulatory enhancers contributes to the induction of CYP24A1 expression by 1alpha,25-dihydroxyvitamin D3. The Journal of Biological Chemistry. 285: 15599-610. PMID 20236932 DOI: 10.1074/jbc.M110.119958  0.478
2010 Pike JW, Meyer MB, Martowicz ML, Bishop KA, Lee SM, Nerenz RD, Goetsch PD. Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3. The Journal of Steroid Biochemistry and Molecular Biology. 121: 130-5. PMID 20214983 DOI: 10.1016/J.Jsbmb.2010.02.036  0.419
2010 Meyer MB, Goetsch PD, Pike JW. Genome-wide analysis of the VDR/RXR cistrome in osteoblast cells provides new mechanistic insight into the actions of the vitamin D hormone. The Journal of Steroid Biochemistry and Molecular Biology. 121: 136-41. PMID 20171278 DOI: 10.1016/j.jsbmb.2010.02.011  0.488
2010 Zella LA, Meyer MB, Nerenz RD, Lee SM, Martowicz ML, Pike JW. Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription. Molecular Endocrinology (Baltimore, Md.). 24: 128-47. PMID 19897601 DOI: 10.1210/Me.2009-0140  0.508
2009 Zella LA, Meyer MB, Nerenz RD, Pike JW. The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes. Endocrinology. 150: 3448-56. PMID 19423758 DOI: 10.1210/en.2009-0113  0.489
2009 Pike JW, Meyer MB, Martowicz ML. New techniques in transcription research extend our understanding of the molecular actions of the vitamin D hormone Ibms Bonekey. 6: 169-180. DOI: 10.1138/20090376  0.348
2008 Zella LA, Shevde NK, Hollis BW, Cooke NE, Pike JW. Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo. Endocrinology. 149: 3656-67. PMID 18372326 DOI: 10.1210/en.2008-0042  0.451
2008 Nerenz RD, Martowicz ML, Pike JW. An enhancer 20 kilobases upstream of the human receptor activator of nuclear factor-kappaB ligand gene mediates dominant activation by 1,25-dihydroxyvitamin D3. Molecular Endocrinology (Baltimore, Md.). 22: 1044-56. PMID 18202151 DOI: 10.1210/Me.2007-0380  0.476
2007 Pike JW, Zella LA, Meyer MB, Fretz JA, Kim S. Molecular actions of 1,25-dihydroxyvitamin D3 on genes involved in calcium homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: V16-9. PMID 18290714 DOI: 10.1359/jbmr.07s207  0.405
2007 Meyer MB, Zella LA, Nerenz RD, Pike JW. Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo. The Journal of Biological Chemistry. 282: 22344-52. PMID 17556365 DOI: 10.1074/jbc.M703475200  0.415
2007 Zella LA, Chang CY, McDonnell DP, Pike JW. The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs. Archives of Biochemistry and Biophysics. 460: 206-12. PMID 17254542 DOI: 10.1016/J.Abb.2006.12.016  0.362
2007 Fretz JA, Zella LA, Kim S, Shevde NK, Pike JW. 1,25-Dihydroxyvitamin D3 induces expression of the Wnt signaling co-regulator LRP5 via regulatory elements located significantly downstream of the gene's transcriptional start site. The Journal of Steroid Biochemistry and Molecular Biology. 103: 440-5. PMID 17229572 DOI: 10.1016/j.jsbmb.2006.11.018  0.32
2007 Pike JW, Meyer MB, Watanuki M, Kim S, Zella LA, Fretz JA, Yamazaki M, Shevde NK. Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor. The Journal of Steroid Biochemistry and Molecular Biology. 103: 389-95. PMID 17223545 DOI: 10.1016/j.jsbmb.2006.12.050  0.475
2007 Zella LA, Kim S, Shevde NK, Pike JW. Enhancers located in the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3. The Journal of Steroid Biochemistry and Molecular Biology. 103: 435-9. PMID 17218097 DOI: 10.1016/j.jsbmb.2006.12.019  0.496
2007 Kim S, Yamazaki M, Zella LA, Meyer MB, Fretz JA, Shevde NK, Pike JW. Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D3. The Journal of Steroid Biochemistry and Molecular Biology. 103: 430-4. PMID 17197168 DOI: 10.1016/j.jsbmb.2006.12.020  0.447
2006 Kim S, Yamazaki M, Zella LA, Shevde NK, Pike JW. Activation of receptor activator of NF-kappaB ligand gene expression by 1,25-dihydroxyvitamin D3 is mediated through multiple long-range enhancers. Molecular and Cellular Biology. 26: 6469-86. PMID 16914732 DOI: 10.1128/MCB.00353-06  0.349
2006 Fretz JA, Zella LA, Kim S, Shevde NK, Pike JW. 1,25-Dihydroxyvitamin D3 regulates the expression of low-density lipoprotein receptor-related protein 5 via deoxyribonucleic acid sequence elements located downstream of the start site of transcription. Molecular Endocrinology (Baltimore, Md.). 20: 2215-30. PMID 16613987 DOI: 10.1210/me.2006-0102  0.317
2006 Meyer MB, Watanuki M, Kim S, Shevde NK, Pike JW. The human transient receptor potential vanilloid type 6 distal promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,25-dihydroxyvitamin D3 in intestinal cells. Molecular Endocrinology (Baltimore, Md.). 20: 1447-61. PMID 16574738 DOI: 10.1210/me.2006-0031  0.493
2006 Zella LA, Kim S, Shevde NK, Pike JW. Enhancers located within two introns of the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3. Molecular Endocrinology (Baltimore, Md.). 20: 1231-47. PMID 16497728 DOI: 10.1210/me.2006-0015  0.495
2006 Pike JW. New nonsteroidal vitamin D receptor modulators: Are these ligands the real deal? Bonekey-Osteovision. 3: 14-18. DOI: 10.1138/20060217  0.384
2006 Pike JW, Watanuki M, Shevde NK. Vitamin D3: Synthesis, Actions, and Mechanisms in the Intestine and Colon Physiology of the Gastrointestinal Tract. 2: 1753-1771. DOI: 10.1016/B978-012088394-3/50072-6  0.348
2005 Liu Y, Shen Q, Malloy PJ, Soliman E, Peng X, Kim S, Pike JW, Feldman D, Christakos S. Enhanced coactivator binding and transcriptional activation of mutant vitamin D receptors from patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets by phosphorylation and vitamin D analogs. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1680-91. PMID 16059639 DOI: 10.1359/JBMR.050410  0.458
2005 Kim S, Shevde NK, Pike JW. 1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 305-17. PMID 15647825 DOI: 10.1359/JBMR.041112  0.425
2005 Pike JW. Vitamin D Analogs: An Overview Vitamin D. 2: 1403-1404. DOI: 10.1016/B978-012252687-9/50083-8  0.398
2004 Fan X, Roy EM, Murphy TC, Nanes MS, Kim S, Pike JW, Rubin J. Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells. Journal of Cellular Biochemistry. 93: 807-18. PMID 15389882 DOI: 10.1002/jcb.20217  0.399
2003 Yamamoto H, Shevde NK, Warrier A, Plum LA, DeLuca HF, Pike JW. 2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts. The Journal of Biological Chemistry. 278: 31756-65. PMID 12796488 DOI: 10.1074/Jbc.M304737200  0.506
2003 Pike JW, Pathrose P, Barmina O, Chang CY, McDonnell DP, Yamamoto H, Shevde NK. Synthetic LXXLL peptide antagonize 1,25-dihydroxyvitamin D3-dependent transcription. Journal of Cellular Biochemistry. 88: 252-8. PMID 12520523 DOI: 10.1002/Jcb.10336  0.399
2002 Pathrose P, Barmina O, Chang CY, McDonnell DP, Shevde NK, Pike JW. Inhibition of 1,25-dihydroxyvitamin D3-dependent transcription by synthetic LXXLL peptide antagonists that target the activation domains of the vitamin D and retinoid X receptors. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 2196-205. PMID 12469913 DOI: 10.1359/Jbmr.2002.17.12.2196  0.428
2002 Pike JW, Yamamoto H, Shevde NK. Vitamin D receptor-mediated gene regulation mechanisms and current concepts of vitamin D analog selectivity. Advances in Renal Replacement Therapy. 9: 168-74. PMID 12203198  0.46
2000 Brown SB, Brierley TT, Palanisamy N, Salusky IB, Goodman W, Brandi ML, Drüeke TB, Sarfati E, Ureña P, Chaganti RS, Pike JW, Arnold A. Vitamin D receptor as a candidate tumor-suppressor gene in severe hyperparathyroidism of uremia. The Journal of Clinical Endocrinology and Metabolism. 85: 868-72. PMID 10690903 DOI: 10.1210/Jcem.85.2.6426  0.334
1999 Malloy PJ, Pike JW, Feldman D. The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets. Endocrine Reviews. 20: 156-88. PMID 10204116 DOI: 10.1210/edrv.20.2.0359  0.414
1999 Yamamoto H, Miyamoto K, Li B, Taketani Y, Kitano M, Inoue Y, Morita K, Pike JW, Takeda E. The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 14: 240-7. PMID 9933478 DOI: 10.1359/jbmr.1999.14.2.240  0.456
1998 Pike JW. The Vitamin D Receptor: Discovery, Structure, and Function Advances in Organ Biology. 5: 213-241. DOI: 10.1016/S1569-2590(08)60114-7  0.4
1997 Clemens TL, Tang H, Maeda S, Kesterson RA, Demayo F, Pike JW, Gundberg CM. Analysis of osteocalcin expression in transgenic mice reveals a species difference in vitamin D regulation of mouse and human osteocalcin genes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 12: 1570-6. PMID 9333117 DOI: 10.1359/jbmr.1997.12.10.1570  0.446
1997 Miyamoto K, Kesterson RA, Yamamoto H, Taketani Y, Nishiwaki E, Tatsumi S, Inoue Y, Morita K, Takeda E, Pike JW. Structural organization of the human vitamin D receptor chromosomal gene and its promoter. Molecular Endocrinology (Baltimore, Md.). 11: 1165-79. PMID 9212063 DOI: 10.1210/mend.11.8.9951  0.344
1997 Uchida M, Ozonco K, Pike JW. In vitro binding of vitamin D receptor occupied by 24R,25-dihydroxyvitamin D3 to vitamin D responsive element of human osteocalcin gene. The Journal of Steroid Biochemistry and Molecular Biology. 60: 181-7. PMID 9191975  0.461
1996 Jin CH, Kerner SA, Hong MH, Pike JW. Transcriptional activation and dimerization functions in the human vitamin D receptor. Molecular Endocrinology (Baltimore, Md.). 10: 945-57. PMID 8843411 DOI: 10.1210/mend.10.8.8843411  0.431
1996 Jin CH, Pike JW. Human vitamin D receptor-dependent transactivation in Saccharomyces cerevisiae requires retinoid X receptor. Molecular Endocrinology (Baltimore, Md.). 10: 196-205. PMID 8825559 DOI: 10.1210/MEND.10.2.8825559  0.381
1996 Arbelle JE, Chen H, Gaead MA, Allegretto EA, Pike JW, Adams JS. Inhibition of vitamin D receptor-retinoid X receptor-vitamin D response element complex formation by nuclear extracts of vitamin D-resistant New World primate cells. Endocrinology. 137: 786-9. PMID 8593831 DOI: 10.1210/ENDO.137.2.8593831  0.429
1995 Imai Y, Pike JW, Koeffler HP. Potent vitamin D3 analogs: their abilities to enhance transactivation and to bind to the vitamin D3 response element. Leukemia Research. 19: 147-58. PMID 7700077 DOI: 10.1016/0145-2126(94)00127-V  0.481
1995 Allegretto EA, Shevde N, Zou A, Howell SR, Boehm MF, Hollis BW, Pike JW. Retinoid X receptor acts as a hormone receptor in vivo to induce a key metabolic enzyme for 1,25-dihydroxyvitamin D3. The Journal of Biological Chemistry. 270: 23906-9. PMID 7592579 DOI: 10.1074/jbc.270.41.23906  0.47
1994 Pavlin D, Bedalov A, Kronenberg MS, Kream BE, Rowe DW, Smith CL, Pike JW, Lichtler AC. Analysis of regulatory regions in the COL1A1 gene responsible for 1,25-dihydroxyvitamin D3-mediated transcriptional repression in osteoblastic cells. Journal of Cellular Biochemistry. 56: 490-501. PMID 7890807 DOI: 10.1002/Jcb.240560409  0.5
1993 Kesterson RA, Stanley L, DeMayo F, Finegold M, Pike JW. The human osteocalcin promoter directs bone-specific vitamin D-regulatable gene expression in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 7: 462-7. PMID 8483481 DOI: 10.1210/MEND.7.3.8483481  0.43
1993 Santiso-Mere D, Sone T, Hilliard GM, Pike JW, McDonnell DP. Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems. Molecular Endocrinology (Baltimore, Md.). 7: 833-9. PMID 8413308 DOI: 10.1210/Mend.7.7.8413308  0.507
1993 Yagi H, Ozono K, Miyake H, Nagashima K, Kuroume T, Pike JW. A new point mutation in the deoxyribonucleic acid-binding domain of the vitamin D receptor in a kindred with hereditary 1,25-dihydroxyvitamin D-resistant rickets. The Journal of Clinical Endocrinology and Metabolism. 76: 509-12. PMID 8381803 DOI: 10.1210/JCEM.76.2.8381803  0.444
1993 Berdal A, Hotton D, Pike JW, Mathieu H, Dupret J. Cell- and Stage-Specific Expression of Vitamin D Receptor and Calbindin Genes in Rat Incisor: Regulation by 1,25-Dihydroxyvitamin D3 Developmental Biology. 155: 172-179. PMID 8380146 DOI: 10.1006/Dbio.1993.1016  0.456
1992 Ozono K, Sone T, Pike JW. The genomic mechanism of action of 1,25-dihydroxyvitamin D3. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 6: 1021-7. PMID 1665675 DOI: 10.1002/JBMR.5650061002  0.465
1992 Sone T, Ozono K, Pike JW. A 55-kilodalton accessory factor facilitates vitamin D receptor DNA binding. Molecular Endocrinology (Baltimore, Md.). 5: 1578-86. PMID 1664043 DOI: 10.1210/MEND-5-11-1578  0.441
1992 Nakajima S, Yamaoka K, Okada S, Pike JW, Seino Y, Haussler MR. 1,25-Dihydroxyvitamin D3 does not up-regulate vitamin D receptor messenger ribonucleic acid levels in hypophosphatemic mice. Bone and Mineral. 19: 201-213. PMID 1335319 DOI: 10.1016/0169-6009(92)90870-J  0.404
1992 Balmain N, Hauchecorne M, Motron P, Pike J, Cuisinier-Gleizes P, Mathieu H. 1.25(OH)2D3 receptors and calbindins-D in the chondrocytes of rat growth cartilage Bone and Mineral. 17: 136. DOI: 10.1016/0169-6009(92)91885-M  0.397
1992 Balmain N, Hauchecorne M, Motron P, Pike J, Moscofian A, Cuisinier-Gleizes P, Mathieu H. Effects of vitamin D on the lung Bone and Mineral. 17: 114. DOI: 10.1016/0169-6009(92)91797-M  0.309
1991 Liao J, Ozono K, Sone T, McDonnell DP, Pike JW. Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. Proceedings of the National Academy of Sciences of the United States of America. 87: 9751-5. PMID 2175914 DOI: 10.1073/Pnas.87.24.9751  0.485
1991 Malloy PJ, Hochberg Z, Tiosano D, Pike JW, Hughes MR, Feldman D. The molecular basis of hereditary 1,25-dihydroxyvitamin D3 resistant rickets in seven related families. The Journal of Clinical Investigation. 86: 2071-9. PMID 2174914 DOI: 10.1172/JCI114944  0.313
1991 Naveh-Many T, Marx R, Keshet E, Pike JW, Silver J. Regulation of 1,25-dihydroxyvitamin D3 receptor gene expression by 1,25-dihydroxyvitamin D3 in the parathyroid in vivo. The Journal of Clinical Investigation. 86: 1968-75. PMID 2174913 DOI: 10.1172/JCI114931  0.467
1991 Smith CL, Hager GL, Pike JW, Marx SJ. Overexpression of the human vitamin D3 receptor in mammalian cells using recombinant adenovirus vectors. Molecular Endocrinology (Baltimore, Md.). 5: 867-78. PMID 1656244 DOI: 10.1210/Mend-5-6-867  0.36
1991 Pike JW. Vitamin D3 receptors: Structure and function in transcription Annual Review of Nutrition. 11: 189-216. PMID 1654066 DOI: 10.1146/ANNUREV.NU.11.070191.001201  0.508
1991 Hughes MR, Malloy PJ, O'Malley BW, Pike JW, Feldman D. Genetic defects of the 1,25-dihydroxyvitamin D3 receptor. Journal of Receptor Research. 11: 699-716. PMID 1653354 DOI: 10.3109/10799899109066437  0.383
1991 Sone T, Kerner S, Pike J. Vitamin D receptor interaction with specific DNA. Association as a 1,25-dihydroxyvitamin D3-modulated heterodimer. Journal of Biological Chemistry. 266: 23296-23305. DOI: 10.1016/s0021-9258(18)54496-3  0.426
1990 Hughes M, Malloy P, Kieback D, McDonnell D, Feldman D, Pike JW, O'Malley B. Human vitamin D receptor mutations: identification of molecular defects in hypocalcemic vitamin D resistant rickets. Advances in Experimental Medicine and Biology. 255: 491-503. PMID 2618873 DOI: 10.1007/978-1-4684-5679-0_52  0.434
1990 Sone T, Marx SJ, Liberman UA, Pike JW. A unique point mutation in the human vitamin D receptor chromosomal gene confers hereditary resistance to 1,25-dihydroxyvitamin D3 Molecular Endocrinology. 4: 623-631. PMID 2177843 DOI: 10.1210/MEND-4-4-623  0.44
1990 Barsony J, Pike JW, DeLuca HF, Marx SJ. Immunocytology with microwave-fixed fibroblasts shows 1α,25-dihydroxyvitamin d3-dependent rapid and estrogen-dependent slow reorganization of vitamin D receptors Journal of Cell Biology. 111: 2385-2395. PMID 2177476 DOI: 10.1083/jcb.111.6.2385  0.398
1990 Schüle R, Umesono K, Mangelsdorf DJ, Bolado J, Pike JW, Evans RM. Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell. 61: 497-504. PMID 2159384 DOI: 10.1016/0092-8674(90)90531-I  0.41
1990 Sone T, McDonnell DP, O'Malley BW, Pike JW. Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies. Journal of Biological Chemistry. 265: 21997-22003. DOI: 10.1016/s0021-9258(18)45838-3  0.391
1990 Ozono K, Liao J, Kerner SA, Scott RA, Pike JW. The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer. Journal of Biological Chemistry. 265: 21881-21888. DOI: 10.1016/s0021-9258(18)45821-8  0.381
1989 Hughes MR, Malloy PJ, Kieback DG, Kesterson RA, Pike JW, Feldman D, O'Malley BW. Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets. Science (New York, N.Y.). 242: 1702-5. PMID 2849209 DOI: 10.1126/SCIENCE.2849209  0.37
1989 Kerner SA, Scott RA, Pike JW. Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3. Proceedings of the National Academy of Sciences of the United States of America. 86: 4455-9. PMID 2786632 DOI: 10.1073/PNAS.86.12.4455  0.391
1989 Ritchie HH, Hughes MR, Thompson ET, Malloy PJ, Hochberg Z, Feldman D, Pike JW, O'Malley BW. An ochre mutation in the vitamin D receptor gene causes hereditary 1,25-dihydroxyvitamin D3-resistant rickets in three families Proceedings of the National Academy of Sciences of the United States of America. 86: 9783-9787. PMID 2557627 DOI: 10.1073/Pnas.86.24.9783  0.396
1989 McDonnell DP, Pike JW, Drutz DJ, Butt TR, O'Malley BW. Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. Molecular and Cellular Biology. 9: 3517-23. PMID 2552296 DOI: 10.1128/mcb.9.8.3517-3523.1989  0.475
1989 McDonnell DP, Scott RA, Kerner SA, O'Malley BW, Pike JW. Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. Molecular Endocrinology (Baltimore, Md.). 3: 635-44. PMID 2542779 DOI: 10.1210/Mend-3-4-635  0.342
1989 Sone T, Scott R, Hughes M, Malloy P, Feldman D, O'Malley B, Pike J. Mutant vitamin D receptors which confer hereditary resistance to 1,25-dihydroxyvitamin D3 in humans are transcriptionally inactive in vitro Journal of Biological Chemistry. 264: 20230-20234. DOI: 10.1016/s0021-9258(19)47051-8  0.432
1989 Huang YC, Lee S, Stolz R, Gabrielides C, Pansini-Porta A, Bruns ME, Bruns DE, Miffin TE, Pike JW, Christakos S. Effect of Hormones and Development on the Expression of the Rat 1,25-Dihydroxyvitamin D3 Receptor Gene Journal of Biological Chemistry. 264: 17454-17461. DOI: 10.1016/s0021-9258(18)71516-0  0.396
1988 Mangelsdorf DJ, Komm BS, McDonnell DP, Pike JW, Haussler MR. Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone. Biochemistry. 26: 8332-8. PMID 3442659 DOI: 10.1021/Bi00399A046  0.385
1988 Berger U, Wilson P, McClelland RA, Colston K, Haussler MR, Pike JW, Coombes RC. Immunocytochemical detection of 1,25-dihydroxyvitamin D receptors in normal human tissues The Journal of Clinical Endocrinology and Metabolism. 67: 607-613. PMID 2842365 DOI: 10.1210/Jcem-67-3-607  0.339
1988 Abdel-Malek ZA, Ross R, Trinkle L, Swope V, Pike JW, Nordlund JJ. Hormonal effects of vitamin D3 on epidermal melanocytes. Journal of Cellular Physiology. 136: 273-80. PMID 2842346 DOI: 10.1002/JCP.1041360209  0.44
1988 McDonnell DP, Pike JW, O'Malley BW. The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor. Journal of Steroid Biochemistry. 30: 41-6. PMID 2838696 DOI: 10.1016/0022-4731(88)90074-X  0.377
1988 Baker AR, McDonnell DP, Hughes M, Crisp TM, Mangelsdorf DJ, Haussler MR, Pike JW, Shine J, O'Malley BW. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 3294-8. PMID 2835767 DOI: 10.1073/Pnas.85.10.3294  0.326
1988 Clemens TL, Garrett KP, Zhou XY, Pike JW, Haussler MR, Dempster DW. Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells Endocrinology. 122: 1224-1230. PMID 2831024 DOI: 10.1210/Endo-122-4-1224  0.436
1987 McDonnell DP, Mangelsdorf DJ, Pike JW, Haussler MR, O'Malley BW. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science (New York, N.Y.). 235: 1214-7. PMID 3029866 DOI: 10.1126/Science.3029866  0.424
1987 Pike JW. Emerging concepts on the biologic role and mechanism of action of 1,25-dihydroxyvitamin D3 Steroids. 49: 3-27. PMID 2842897 DOI: 10.1016/0039-128X(87)90077-8  0.322
1987 Allegretto EA, Pike JW, Haussler MR. C-terminal proteolysis of the avian 1,25-dihydroxyvitamin D3 receptor. Biochemical and Biophysical Research Communications. 147: 479-485. PMID 2820401 DOI: 10.1016/S0006-291X(87)80146-8  0.411
1987 Mangelsdorf DJ, Pike JW, Haussler MR. Avian and mammalian receptors for 1,25-dihydroxyvitamin D3: in vitro translation to characterize size and hormone-dependent regulation Proceedings of the National Academy of Sciences of the United States of America. 84: 354-358. PMID 2432610 DOI: 10.1073/Pnas.84.2.354  0.391
1987 Allegretto EA, Pike JW, Haussler MR. Immunochemical detection of unique proteolytic fragments of the chick 1,25-dihydroxyvitamin D3 receptor. Distinct 20-kDa DNA-binding and 45-kDa hormone-binding species. Journal of Biological Chemistry. 262: 1312-1319. DOI: 10.1016/s0021-9258(19)75788-3  0.301
1987 Pike JW, Sleator NM, Haussler MR. Chicken intestinal receptor for 1,25-dihydroxyvitamin D3. Immunologic characterization and homogeneous isolation of a 60,000-dalton protein. Journal of Biological Chemistry. 262: 1305-1311. DOI: 10.1016/s0021-9258(19)75787-1  0.341
1987 Berger U, Wilson P, Colston K, Coombes RC, Pike JW, Haussler MR. Immunocytochemical detection of 1,25-dihydroxyvitamin D3 receptor in normal human tissues Bone. 8: 264. DOI: 10.1016/8756-3282(87)90180-3  0.324
1986 Haussler CA, Marion SL, Pike JW, Haussler MR. 1,25-dihydroxyvitamin D3 inhibits the clonogenic growth of transformed cells via its receptor Biochemical and Biophysical Research Communications. 139: 136-143. PMID 3021122 DOI: 10.1016/S0006-291X(86)80090-0  0.424
1986 Pike JW, Allegretto EA, Kelly MA, Donaldson CA, Marion SL, Mangelsdorf DJ, Haussler MR. 1,25-Dihydroxyvitamin D3 receptors: altered functional domains are associated with cellular resistance to vitamin D3. Advances in Experimental Medicine and Biology. 196: 377-390. PMID 3012980 DOI: 10.1007/978-1-4684-5101-6_25  0.451
1986 Pike JW, Haussler MR. Monoclonal antibodies as probes in the characterization of 1,25-dihydroxyvitamin D3 receptors. Methods in Enzymology. 123: 199-211. PMID 3010041 DOI: 10.1016/S0076-6879(86)23024-4  0.395
1985 Pike JW, Sleator NM. Hormone-dependent phosphorylation of the 1,25-dihydroxyvitamin D3 receptor in mouse fibroblasts. Biochemical and Biophysical Research Communications. 131: 378-85. PMID 2994658 DOI: 10.1016/0006-291X(85)91813-3  0.422
1985 Pike JW. Intracellular receptors mediate the biologic action of 1,25-dihydroxyvitamin D3 Nutrition Reviews. 43: 161-168. PMID 2991827 DOI: 10.1111/J.1753-4887.1985.TB02406.X  0.404
1985 Kelly MA, Marion SL, Donaldson CA, Pike JW, Haussler MR. A variant form of the 1,25-dihydroxyvitamin D3 receptor with low apparent hormone affinity in cultured monkey kidney cells (LLC-MK2). A model for tissue resistance to vitamin D. Journal of Biological Chemistry. 260: 1545-1549. DOI: 10.1016/S0021-9258(18)89627-2  0.407
1985 Allegretto EA, Pike JW. Trypsin cleavage of chick 1,25-dihydroxyvitamin D3 receptors. Generation of discrete polypeptides which retain hormone but are unreactive to DNA and monoclonal antibody. Journal of Biological Chemistry. 260: 10139-10145. DOI: 10.1016/s0021-9258(17)39224-4  0.303
1984 Pike JW, Dokoh S, Haussler MR, Liberman UA, Marx SJ, Charles EIL. Vitamin D3-resistant fibroblasts have immunoassayable 1,25-dihydroxyvitamin D3 receptors Science. 224: 879-881. PMID 6326262 DOI: 10.1126/SCIENCE.6326262  0.402
1984 Mangelsdorf DJ, Koeffler HP, Donaldson CA, Pike JW, Haussler MR. 1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells. The Journal of Cell Biology. 98: 391-8. PMID 6319426 DOI: 10.1083/JCB.98.2.391  0.418
1984 Dokoh S, Haussler MR, Pike JW. Development of a radioligand immunoassay for 1,25-dihydroxycholecalciferol receptors utilizing monoclonal antibody. The Biochemical Journal. 221: 129-36. PMID 6087801 DOI: 10.1042/BJ2210129  0.36
1984 Pike JW. Monoclonal antibodies to chick intestinal receptors for 1,25-dihydroxyvitamin D3. Interaction and effects of binding on receptor function. Journal of Biological Chemistry. 259: 1167-1173. DOI: 10.1016/s0021-9258(17)43583-6  0.318
1984 Chandler JS, Chandler SK, Pike JW, Haussler MR. 1,25-Dihydroxyvitamin D3 induces 25-hydroxyvitamin D3-24-hydroxylase in a cultured monkey kidney cell line (LLC-MK2) apparently deficient in the high affinity receptor for the hormone. Journal of Biological Chemistry. 259: 2214-2222. DOI: 10.1016/s0021-9258(17)43340-0  0.398
1983 Toverud SU, Boass A, Haussler MR, Pike JW. Circulating levels and function of 1,25-(OH)2D3 in lactation Journal of Steroid Biochemistry. 19: 505-510. PMID 6688449 DOI: 10.1016/0022-4731(83)90210-8  0.37
1983 Dokoh S, Donaldson CA, Marion SL, Pike JW, Haussler MR. The ovary: a target organ for 1,25-dihydroxyvitamin D3. Endocrinology. 112: 200-206. PMID 6291916 DOI: 10.1210/Endo-112-1-200  0.407
1983 Pike JW, Marion SL, Donaldson CA, Haussler MR. Serum and monoclonal antibodies against the chick intestinal receptor for 1,25-dihydroxyvitamin D3. Generation by a preparation enriched in a 64,000-dalton protein. Journal of Biological Chemistry. 258: 1289-1296. DOI: 10.1016/s0021-9258(18)33191-0  0.303
1983 Pike JW, Haussler MR. Association of 1,25-dihydroxyvitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor-mediated migration to the nucleus. Journal of Biological Chemistry. 258: 8554-8560. DOI: 10.1016/s0021-9258(18)32092-1  0.307
1982 Pike JW, Kelly MA, Haussler MR. High performance liquid chromatography of the 1,25-dihydroxyvitamin D3 receptor: its application toward resolution of receptor-monoclonal antibody complexes. Biochemical and Biophysical Research Communications. 109: 902-907. PMID 6297493 DOI: 10.1016/0006-291X(82)92025-3  0.338
1982 Pike JW, Donaldson CA, Marion SL, Haussler MR. Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1α,25-dihydroxyvitamin D3 receptor Proceedings of the National Academy of Sciences of the United States of America. 79: 7719-7723. PMID 6296847 DOI: 10.1073/Pnas.79.24.7719  0.381
1982 Pike JW. Receptors for 1,25-dihydroxyvitamin D3 in chick pancreas: A partial physical and functional characterization Journal of Steroid Biochemistry. 16: 385-395. PMID 6283269 DOI: 10.1016/0022-4731(82)90050-4  0.445
1982 Pike JW. Interaction between 1,25-dihydroxyvitamin D3 receptors and intestinal nuclei. Binding to nuclear constituents in vitro. Journal of Biological Chemistry. 257: 6766-6775. DOI: 10.1016/s0021-9258(18)34496-x  0.361
1981 Boass A, Toverud SU, Pike JW, Haussler MR. Calcium Metabolism during Lactation: Enhanced Intestinal Calcium Absorption in Vitamin D-Deprived, Hypocalcemic Rats Endocrinology. 109: 900-907. PMID 6894899 DOI: 10.1210/Endo-109-3-900  0.368
1981 Dokoh S, Pike JW, Chandler JS, Mancini JM, Haussler MR. An improved radioreceptor assay for 1,25-dihydroxyvitamin D in human plasma. Analytical Biochemistry. 116: 211-222. PMID 6272612 DOI: 10.1016/0003-2697(81)90346-8  0.317
1981 Pike JW. Evidence for a reactive sulfhydryl in the DNA binding domain of the 1,25-dihydroxyvitamin D3 receptor Biochemical and Biophysical Research Communications. 100: 1713-1719. PMID 6271130 DOI: 10.1016/0006-291X(81)90716-6  0.303
1981 Pike JW. Intestinal 1,25-dihydroxyvitamin D3 receptors: hormone-dependent uptake and saturability of nuclear components in vitro. Life Sciences. 28: 957-63. PMID 6261069 DOI: 10.1016/0024-3205(81)90060-6  0.375
1980 Pike JW, Goozé LL, Haussler MR. Biochemical evidence for 1,25-dihydroxyvitamin D receptor macromolecules in parathyroid, pancreatic, pituitary, and placental tissues. Life Sciences. 26: 407-414. PMID 7366331 DOI: 10.1016/0024-3205(80)90158-7  0.383
1980 Haussler MR, Chandler JS, Hagan LA, Pike JW. [64] Use of chick kidney to enzymatically generate radiolabeled 1,25-dihydroxyvitamin D and other vitamin D metabolites Methods in Enzymology. 67: 529-542. PMID 6966030 DOI: 10.1016/S0076-6879(80)67066-9  0.407
1980 Chandler JS, Pike JW, Hagan LA, Haussler MR. [63] A sensitive radioreceptor assay for 1α,25-dihydroxyvitamin D in biological fluid Methods in Enzymology. 67: 522-528. PMID 6892721 DOI: 10.1016/S0076-6879(80)67065-7  0.438
1980 Pike JW, Haussler MR. [62] Characteristics and purification of the intestinal receptor for 1,25-dihydroxyvitamin D Methods in Enzymology. 67: 508-522. PMID 6245335 DOI: 10.1016/S0076-6879(80)67064-5  0.457
1980 Pike JW, Haussler MR. Purification of chicken intestinal receptor for 1,25-dihydroxyvitamin D. Proceedings of the National Academy of Sciences of the United States of America. 76: 5485-9. PMID 230478 DOI: 10.1073/PNAS.76.11.5485  0.401
1979 Chandler JS, Pike JW, Haussler MR. 1,25-Dihydroxyvitamin D3 receptors in rat kidney cytosol. Biochemical and Biophysical Research Communications. 90: 1057-1063. PMID 508334 DOI: 10.1016/0006-291X(79)91933-8  0.387
1979 Pike JW, Parker JB, Haussler MR, Boass A, Toverud SV. Dynamic changes in circulating 1,25-dihydroxyvitamin D during reproduction in rats. Science (New York, N.Y.). 204: 1427-9. PMID 451573 DOI: 10.1126/SCIENCE.451573  0.359
1979 Haussler M, Drezner M, Pike J, Hagan L. 1,25-DIHYDROXYVITAMIN D (1,25-(OH)2D) AND PARATHYROID HORMONE (PTH) IN CALCIUM AND PHOSPHATE HOMEOSTASIS: BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL ASPECTS. Acta Endocrinologica. 92: S481-S487. DOI: 10.1530/ACTA.0.091S481  0.365
1978 Spanos E, Barrett D, Macintyre I, Pike JW, Safilian EF, Haussler MR. Effect of growth hormone on vitamin D metabolism. Nature. 273: 246-247. PMID 643088 DOI: 10.1038/273246A0  0.373
1978 Pike JW, Spanos E, Colston KW, MacIntyre I, Haussler MR. Influence of estrogen on renal vitamin D hydroxylases and serum 1alpha,25-(OH)2D3 in chicks. The American Journal of Physiology. 235: E338-43. PMID 211856 DOI: 10.1152/AJPENDO.1978.235.3.E338  0.381
1977 Boass A, Toverud SU, Mccain TA, Pike JW, Haussler MR. Elevated serum levels of 1α, 25-dihydroxycholecalciferol in lactating rats Nature. 267: 630-632. PMID 876385 DOI: 10.1038/267630A0  0.311
1976 Spanos E, Pike JW, Haussler MR, Colston KW, Evans IM, Goldner AM, McCain TA, MacIntyre I. Circulating 1alpha,25-dihydroxyvitamin D in the chicken: enhancement by injection of prolactin and during egg laying. Life Sciences. 19: 1751-6. PMID 1004133 DOI: 10.1016/0024-3205(76)90083-7  0.369
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