| Year |
Citation |
Score |
| 2018 |
Ingram R, Kang H, Lightman S, Jane DE, Bortolotto ZA, Collingridge GL, Lodge D, Volianskis A. Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity. Neuropharmacology. PMID 29885421 DOI: 10.1016/j.neuropharm.2018.06.008 |
0.84 |
|
| 2016 |
Collingridge GL, Lee Y, Bortolotto ZA, Kang H, Lodge D. Antidepressant Actions of Ketamine Versus Hydroxynorketamine. Biological Psychiatry. PMID 27817845 DOI: 10.1016/j.biopsych.2016.06.029 |
0.84 |
|
| 2016 |
Collingridge GL, Lodge D, Mayer M, Turrigiano G, Frenguelli BG. Ionotropic glutamate receptors: still exciting after all these years. Neuropharmacology. PMID 27659748 DOI: 10.1016/j.neuropharm.2016.09.019 |
0.84 |
|
| 2016 |
Kang H, Park P, Bortolotto ZA, Brandt SD, Colestock T, Wallach J, Collingridge GL, Lodge D. Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties. Neuropharmacology. PMID 27520396 DOI: 10.1016/j.neuropharm.2016.08.004 |
0.84 |
|
| 2016 |
Wallach J, Kang H, Colestock T, Morris H, Bortolotto ZA, Collingridge GL, Lodge D, Halberstadt AL, Brandt SD, Adejare A. Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues. Plos One. 11: e0157021. PMID 27314670 DOI: 10.1371/journal.pone.0157021 |
0.84 |
|
| 2016 |
Wood CM, Nicolas CS, Choi SL, Roman E, Nylander I, Fernandez-Teruel A, Kiianmaa K, Bienkowski P, de Jong TR, Colombo G, Chastagnier D, Wafford KA, Collingridge GL, Wildt SJ, Conway-Campbell BL, ... ... Lodge D, et al. Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour. Neuropharmacology. PMID 26987983 DOI: 10.1016/j.neuropharm.2016.03.020 |
0.84 |
|
| 2015 |
Lodge D, Mercier MS. Ketamine and phencyclidine: the good, the bad and the unexpected. British Journal of Pharmacology. 172: 4254-76. PMID 26075331 DOI: 10.1111/bph.13222 |
0.84 |
|
| 2015 |
Wallis JL, Irvine MW, Jane DE, Lodge D, Collingridge GL, Bortolotto ZA. An interchangeable role for kainate and metabotropic glutamate receptors in the induction of rat hippocampal mossy fiber long-term potentiation in vivo. Hippocampus. PMID 25821051 DOI: 10.1002/hipo.22460 |
0.84 |
|
| 2015 |
Wallach J, Kavanagh PV, McLaughlin G, Morris N, Power JD, Elliott SP, Mercier MS, Lodge D, Morris H, Dempster NM, Brandt SD. Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers. Drug Testing and Analysis. 7: 358-67. PMID 25044512 DOI: 10.1002/dta.1689 |
0.84 |
|
| 2014 |
Mercier MS, Lodge D. Group III metabotropic glutamate receptors: pharmacology, physiology and therapeutic potential. Neurochemical Research. 39: 1876-94. PMID 25146900 DOI: 10.1007/s11064-014-1415-y |
0.84 |
|
| 2013 |
Lodge D, Tidball P, Mercier MS, Lucas SJ, Hanna L, Ceolin L, Kritikos M, Fitzjohn SM, Sherwood JL, Bannister N, Volianskis A, Jane DE, Bortolotto ZA, Collingridge GL. Antagonists reversibly reverse chemical LTD induced by group I, group II and group III metabotropic glutamate receptors. Neuropharmacology. 74: 135-46. PMID 23542080 DOI: 10.1016/j.neuropharm.2013.03.011 |
0.84 |
|
| 2013 |
Crabtree JW, Lodge D, Bashir ZI, Isaac JT. GABAA , NMDA and mGlu2 receptors tonically regulate inhibition and excitation in the thalamic reticular nucleus. The European Journal of Neuroscience. 37: 850-9. PMID 23294136 DOI: 10.1111/ejn.12098 |
0.84 |
|
| 2013 |
Mercier MS, Lodge D, Fang G, Nicolas CS, Collett VJ, Jane DE, Collingridge GL, Bortolotto ZA. Characterisation of an mGlu8 receptor-selective agonist and antagonist in the lateral and medial perforant path inputs to the dentate gyrus. Neuropharmacology. 67: 294-303. PMID 23220400 DOI: 10.1016/j.neuropharm.2012.11.020 |
0.84 |
|
| 2013 |
Collingridge GL, Volianskis A, Bannister N, France G, Hanna L, Mercier M, Tidball P, Fang G, Irvine MW, Costa BM, Monaghan DT, Bortolotto ZA, Molnár E, Lodge D, Jane DE. The NMDA receptor as a target for cognitive enhancement. Neuropharmacology. 64: 13-26. PMID 22796429 DOI: 10.1016/j.neuropharm.2012.06.051 |
0.84 |
|
| 2013 |
Sanger H, Hanna L, Colvin EM, Grubisha O, Ursu D, Heinz BA, Findlay JD, Vivier RG, Sher E, Lodge D, Monn JA, Broad LM. Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR. Neuropharmacology. 66: 264-73. PMID 22659090 DOI: 10.1016/j.neuropharm.2012.05.023 |
0.84 |
|
| 2013 |
Lucas SJ, Bortolotto ZA, Collingridge GL, Lodge D. Selective activation of either mGlu2 or mGlu3 receptors can induce LTD in the amygdala. Neuropharmacology. 66: 196-201. PMID 22531751 DOI: 10.1016/j.neuropharm.2012.04.006 |
0.84 |
|
| 2013 |
Hanna L, Ceolin L, Lucas S, Monn J, Johnson B, Collingridge G, Bortolotto Z, Lodge D. Differentiating the roles of mGlu2 and mGlu3 receptors using LY541850, an mGlu2 agonist/mGlu3 antagonist. Neuropharmacology. 66: 114-21. PMID 22445601 DOI: 10.1016/j.neuropharm.2012.02.023 |
0.84 |
|
| 2012 |
Sherwood JL, Amici M, Dargan SL, Culley GR, Fitzjohn SM, Jane DE, Collingridge GL, Lodge D, Bortolotto ZA. Differences in kainate receptor involvement in hippocampal mossy fibre long-term potentiation depending on slice orientation. Neurochemistry International. 61: 482-9. PMID 22564530 DOI: 10.1016/j.neuint.2012.04.021 |
0.84 |
|
| 2012 |
Ceolin L, Bortolotto ZA, Bannister N, Collingridge GL, Lodge D, Volianskis A. A novel anti-epileptic agent, perampanel, selectively inhibits AMPA receptor-mediated synaptic transmission in the hippocampus. Neurochemistry International. 61: 517-22. PMID 22433907 DOI: 10.1016/j.neuint.2012.02.035 |
0.84 |
|
| 2012 |
Lodge D. Translational models of schizophrenia. Neuropharmacology. 62: 1163. PMID 21843536 DOI: 10.1016/j.neuropharm.2011.08.001 |
0.84 |
|
| 2012 |
Lodge D, Jones M, Fletcher E. Non-competitive antagonists of N-methyl-D-aspartate The Nmda Receptor. DOI: 10.1093/acprof:oso/9780192625021.003.0003 |
0.84 |
|
| 2011 |
Ceolin L, Kantamneni S, Barker GR, Hanna L, Murray L, Warburton EC, Robinson ES, Monn JA, Fitzjohn SM, Collingridge GL, Bortolotto ZA, Lodge D. Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6721-31. PMID 21543601 DOI: 10.1523/JNEUROSCI.0418-11.2011 |
0.84 |
|
| 2010 |
Huang LT, Sherwood JL, Sun YJ, Lodge D, Wang Y. Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study. British Journal of Pharmacology. 159: 554-65. PMID 20105181 DOI: 10.1111/j.1476-5381.2009.00529.x |
0.84 |
|
| 2009 |
Nisticò R, Dargan S, Fitzjohn SM, Lodge D, Jane DE, Collingridge GL, Bortolotto ZA. GLUK1 receptor antagonists and hippocampal mossy fiber function. International Review of Neurobiology. 85: 13-27. PMID 19607958 DOI: 10.1016/S0074-7742(09)85002-2 |
0.84 |
|
| 2009 |
Jane DE, Lodge D, Collingridge GL. Kainate receptors: pharmacology, function and therapeutic potential. Neuropharmacology. 56: 90-113. PMID 18793656 DOI: 10.1016/j.neuropharm.2008.08.023 |
0.84 |
|
| 2009 |
Dargan SL, Clarke VR, Alushin GM, Sherwood JL, Nisticò R, Bortolotto ZA, Ogden AM, Bleakman D, Doherty AJ, Lodge D, Mayer ML, Fitzjohn SM, Jane DE, Collingridge GL. ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function. Neuropharmacology. 56: 121-30. PMID 18789344 DOI: 10.1016/j.neuropharm.2008.08.016 |
0.84 |
|
| 2009 |
Lodge D. The history of the pharmacology and cloning of ionotropic glutamate receptors and the development of idiosyncratic nomenclature. Neuropharmacology. 56: 6-21. PMID 18765242 DOI: 10.1016/j.neuropharm.2008.08.006 |
0.84 |
|
| 2007 |
Bartlett TE, Bannister NJ, Collett VJ, Dargan SL, Massey PV, Bortolotto ZA, Fitzjohn SM, Bashir ZI, Collingridge GL, Lodge D. Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus. Neuropharmacology. 52: 60-70. PMID 16904707 DOI: 10.1016/j.neuropharm.2006.07.013 |
0.84 |
|
| 2006 |
Wang Y, Sherwood JL, Lodge D. The alpha4beta2 nicotinic acetylcholine receptor agonist TC-2559 impairs long-term potentiation in the dentate gyrus in vivo. Neuroscience Letters. 406: 183-8. PMID 16935422 DOI: 10.1016/j.neulet.2006.06.075 |
0.84 |
|
| 2006 |
Wang Y, Sherwood JL, Miles CP, Whiffin G, Lodge D. TC-2559 excites dopaminergic neurones in the ventral tegmental area by stimulating alpha4beta2-like nicotinic acetylcholine receptors in anaesthetised rats. British Journal of Pharmacology. 147: 379-90. PMID 16402043 DOI: 10.1038/sj.bjp.0706621 |
0.84 |
|
| 2006 |
Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Hemrick-Luecke SK, Thompson LK, Evans DC, Rasmussen K, Koger D, Lodge D, Martin LJ, Shaw J, Threlkeld PG, Wong DT. Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 5. Bioorganic & Medicinal Chemistry Letters. 16: 2347-51. PMID 16298130 DOI: 10.1016/j.bmcl.2005.11.007 |
0.84 |
|
| 2005 |
Lee DH, Singh JP, Lodge D. Experiments with nitric oxide synthase inhibitors in spinal nerve ligated rats provide no evidence of a role for nitric oxide in neuropathic mechanical allodynia. Neuroscience Letters. 385: 179-83. PMID 15964141 DOI: 10.1016/j.neulet.2005.05.036 |
0.84 |
|
| 2004 |
Smolders I, Lindekens H, Clinckers R, Meurs A, O'Neill MJ, Lodge D, Ebinger G, Michotte Y. In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands. Journal of Neurochemistry. 88: 1068-77. PMID 15009663 DOI: 10.1046/j.1471-4159.2003.02251.x |
0.84 |
|
| 2003 |
Lee DH, Iyengar S, Lodge D. The role of uninjured nerve in spinal nerve ligated rats points to an improved animal model of neuropathic pain. European Journal of Pain (London, England). 7: 473-9. PMID 12935800 DOI: 10.1016/S1090-3801(03)00019-3 |
0.84 |
|
| 2003 |
Lauri SE, Bortolotto ZA, Nistico R, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL. A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus. Neuron. 39: 327-41. PMID 12873388 DOI: 10.1016/S0896-6273(03)00369-6 |
0.84 |
|
| 2003 |
Murray TK, Whalley K, Robinson CS, Ward MA, Hicks CA, Lodge D, Vandergriff JL, Baumbarger P, Siuda E, Gates M, Ogden AM, Skolnick P, Zimmerman DM, Nisenbaum ES, Bleakman D, et al. LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 306: 752-62. PMID 12730350 DOI: 10.1124/jpet.103.049445 |
0.84 |
|
| 2002 |
Smolders I, Bortolotto ZA, Clarke VR, Warre R, Khan GM, O'Neill MJ, Ornstein PL, Bleakman D, Ogden A, Weiss B, Stables JP, Ho KH, Ebinger G, Collingridge GL, Lodge D, et al. Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures. Nature Neuroscience. 5: 796-804. PMID 12080343 DOI: 10.1038/nn880 |
0.84 |
|
| 2002 |
Sharpe EF, Kingston AE, Lodge D, Monn JA, Headley PM. Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo. British Journal of Pharmacology. 135: 1255-62. PMID 11877334 DOI: 10.1038/sj.bjp.0704583 |
0.84 |
|
| 2001 |
Lauri SE, Bortolotto ZA, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL. A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP. Neuron. 32: 697-709. PMID 11719209 DOI: 10.1016/S0896-6273(01)00511-6 |
0.84 |
|
| 2001 |
Vandergriff J, Huff K, Bond A, Lodge D. Potentiation of responses to AMPA on central neurones by LY392098 and LY404187 in vivo. Neuropharmacology. 40: 1003-9. PMID 11406191 DOI: 10.1016/S0028-3908(01)00031-4 |
0.84 |
|
| 2001 |
Lodge D. Neuronal nicotinic receptors: no smoke without fire! Trends in Neurosciences. 24: 132-3. PMID 11294134 DOI: 10.1016/S0166-2236(00)01741-0 |
0.84 |
|
| 2001 |
Lee DH, Katner J, Iyengar S, Lodge D. The effect of lumbar sympathectomy on increased tactile sensitivity in spinal nerve ligated rats. Neuroscience Letters. 298: 99-102. PMID 11163287 DOI: 10.1016/S0304-3940(00)01726-2 |
0.84 |
|
| 2000 |
Doherty AJ, Palmer MJ, Bortolotto ZA, Hargreaves A, Kingston AE, Ornstein PL, Schoepp DD, Lodge D, Collingridge GL. A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices. British Journal of Pharmacology. 131: 239-44. PMID 10991916 DOI: 10.1038/sj.bjp.0703574 |
0.84 |
|
| 2000 |
Bond A, Jones NM, Hicks CA, Whiffin GM, Ward MA, O'Neill MF, Kingston AE, Monn JA, Ornstein PL, Schoepp DD, Lodge D, O'Neill MJ. Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanism of action in vivo. The Journal of Pharmacology and Experimental Therapeutics. 294: 800-9. PMID 10945827 |
0.84 |
|
| 2000 |
O'Neill MJ, Murray TK, McCarty DR, Hicks CA, Dell CP, Patrick KE, Ward MA, Osborne DJ, Wiernicki TR, Roman CR, Lodge D, Fleisch JH, Singh J. ARL 17477, a selective nitric oxide synthase inhibitor, with neuroprotective effects in animal models of global and focal cerebral ischaemia. Brain Research. 871: 234-44. PMID 10899290 DOI: 10.1016/S0006-8993(00)02471-9 |
0.84 |
|
| 2000 |
O'Neill MJ, Bogaert L, Hicks CA, Bond A, Ward MA, Ebinger G, Ornstein PL, Michotte Y, Lodge D. LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia. Neuropharmacology. 39: 1575-88. PMID 10854902 DOI: 10.1016/S0028-3908(99)00250-6 |
0.84 |
|
| 1999 |
Kingston AE, O'Neill MJ, Bond A, Bruno V, Battaglia G, Nicoletti F, Harris JR, Clark BP, Monn JA, Lodge D, Schoepp DD. Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors. Annals of the New York Academy of Sciences. 890: 438-49. PMID 10668448 |
0.84 |
|
| 1999 |
Bortolotto ZA, Clarke VR, Delany CM, Parry MC, Smolders I, Vignes M, Ho KH, Miu P, Brinton BT, Fantaske R, Ogden A, Gates M, Ornstein PL, Lodge D, Bleakman D, et al. Kainate receptors are involved in synaptic plasticity. Nature. 402: 297-301. PMID 10580501 DOI: 10.1038/46290 |
0.84 |
|
| 1999 |
Lam AG, Monn JA, Schoepp DD, Lodge D, McCulloch J. Group II selective metabotropic glutamate receptor agonists and local cerebral glucose use in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1083-91. PMID 10532632 DOI: 10.1097/00004647-199910000-00004 |
0.84 |
|
| 1999 |
Fitzjohn SM, Kingston AE, Lodge D, Collingridge GL. DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterisation and sensitivity to novel mGlu receptor antagonists. Neuropharmacology. 38: 1577-83. PMID 10530819 DOI: 10.1016/S0028-3908(99)00123-9 |
0.84 |
|
| 1999 |
Cushing A, Price-Jones MJ, Graves R, Harris AJ, Hughes KT, Bleakman D, Lodge D. Measurement of calcium flux through ionotropic glutamate receptors using Cytostar-T scintillating microplates. Journal of Neuroscience Methods. 90: 33-6. PMID 10517271 DOI: 10.1016/S0165-0270(99)00058-8 |
0.84 |
|
| 1999 |
Bond A, Ragumoorthy N, Monn JA, Hicks CA, Ward MA, Lodge D, O'Neill MJ. LY379268, a potent and selective Group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal, cerebral ischaemia. Neuroscience Letters. 273: 191-4. PMID 10515191 DOI: 10.1016/S0304-3940(99)00663-1 |
0.84 |
|
| 1999 |
Bond A, Lodge D, Hicks CA, Ward MA, O'Neill MJ. NMDA receptor antagonism, but not AMPA receptor antagonism attenuates induced ischaemic tolerance in the gerbil hippocampus. European Journal of Pharmacology. 380: 91-9. PMID 10513567 DOI: 10.1016/S0014-2999(99)00523-3 |
0.84 |
|
| 1999 |
Anderson BA, Harn NK, Hansen MM, Harkness AR, Lodge D, Leander JD. Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazephine AMPA antagonists. Bioorganic & Medicinal Chemistry Letters. 9: 1953-6. PMID 10450961 DOI: 10.1016/S0960-894X(99)00315-7 |
0.84 |
|
| 1998 |
Fitzjohn SM, Bortolotto ZA, Palmer MJ, Doherty AJ, Ornstein PL, Schoepp DD, Kingston AE, Lodge D, Collingridge GL. The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacology. 37: 1445-58. PMID 9886667 DOI: 10.1016/S0028-3908(98)00145-2 |
0.84 |
|
| 1998 |
Ornstein PL, Arnold MB, Lunn WH, Heinz LJ, Leander JD, Lodge D, Schoepp DD. Heteroatom-substitution as a strategy for increasing the potency of competitive NMDA antagonists. Bioorganic & Medicinal Chemistry Letters. 8: 389-94. PMID 9871691 DOI: 10.1016/S0960-894X(98)00038-9 |
0.84 |
|
| 1998 |
Procter MJ, Houghton AK, Faber ES, Chizh BA, Ornstein PL, Lodge D, Headley PM. Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord. Neuropharmacology. 37: 1287-97. PMID 9849666 DOI: 10.1016/S0028-3908(98)00136-1 |
0.84 |
|
| 1998 |
Vignes M, Clarke VR, Parry MJ, Bleakman D, Lodge D, Ornstein PL, Collingridge GL. The GluR5 subtype of kainate receptor regulates excitatory synaptic transmission in areas CA1 and CA3 of the rat hippocampus. Neuropharmacology. 37: 1269-77. PMID 9849664 DOI: 10.1016/S0028-3908(98)00148-8 |
0.84 |
|
| 1998 |
O'Neill MJ, Bond A, Ornstein PL, Ward MA, Hicks CA, Hoo K, Bleakman D, Lodge D. Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia. Neuropharmacology. 37: 1211-22. PMID 9849659 DOI: 10.1016/S0028-3908(98)00134-8 |
0.84 |
|
| 1998 |
Bleakman D, Lodge D. Neuropharmacology of AMPA and kainate receptors. Neuropharmacology. 37: 1187-204. PMID 9849657 DOI: 10.1016/S0028-3908(98)00139-7 |
0.84 |
|
| 1998 |
Lam AG, Soriano MA, Monn JA, Schoepp DD, Lodge D, McCulloch J. Effects of the selective metabotropic glutamate agonist LY354740 in a rat model of permanent ischaemia. Neuroscience Letters. 254: 121-3. PMID 9779935 DOI: 10.1016/S0304-3940(98)00651-X |
0.84 |
|
| 1998 |
Kingston AE, Lowndes J, Evans N, Clark B, Tomlinson R, Burnett JP, Mayne NG, Cockerham SL, Lodge D. Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines. Neuropharmacology. 37: 277-87. PMID 9681926 DOI: 10.1016/S0028-3908(98)00018-5 |
0.84 |
|
| 1998 |
Pinto A, Gillard S, Moss F, Whyte K, Brust P, Williams M, Stauderman K, Harpold M, Lang B, Newsom-Davis J, Bleakman D, Lodge D, Boot J. Human autoantibodies specific for the alpha1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons. Proceedings of the National Academy of Sciences of the United States of America. 95: 8328-33. PMID 9653186 DOI: 10.1073/pnas.95.14.8328 |
0.84 |
|
| 1998 |
Bond A, O'Neill MJ, Hicks CA, Monn JA, Lodge D. Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia. Neuroreport. 9: 1191-3. PMID 9601692 |
0.84 |
|
| 1998 |
Collingridge GL, Lodge D. 7th Neuropharmacology Conference: Editorial Neuropharmacology. 37: 1185. DOI: 10.1016/S0028-3908(98)00169-5 |
0.84 |
|
| 1997 |
Vignes M, Bleakman D, Lodge D, Collingridge GL. The synaptic activation of the GluR5 subtype of kainate receptor in area CA3 of the rat hippocampus. Neuropharmacology. 36: 1477-81. PMID 9517417 DOI: 10.1016/S0028-3908(97)00158-5 |
0.84 |
|
| 1997 |
Clarke VR, Ballyk BA, Hoo KH, Mandelzys A, Pellizzari A, Bath CP, Thomas J, Sharpe EF, Davies CH, Ornstein PL, Schoepp DD, Kamboj RK, Collingridge GL, Lodge D, Bleakman D. A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission. Nature. 389: 599-603. PMID 9335499 DOI: 10.1038/39315 |
0.84 |
|
| 1997 |
Gillard SE, Volsen SG, Smith W, Beattie RE, Bleakman D, Lodge D. Identification of pore-forming subunit of P-type calcium channels: an antisense study on rat cerebellar Purkinje cells in culture. Neuropharmacology. 36: 405-9. PMID 9175621 DOI: 10.1016/S0028-3908(97)00046-4 |
0.84 |
|
| 1997 |
Bond A, Monn JA, Lodge D. A novel orally active group 2 metabotropic glutamate receptor agonist: LY354740. Neuroreport. 8: 1463-6. PMID 9172154 |
0.84 |
|
| 1997 |
Willis CL, Wacker DA, Bartlett RD, Bleakman D, Lodge D, Chamberlin AR, Bridges RJ. Irreversible inhibition of high-affinity [3H]kainate binding by a novel photoactivatable analogue: (2'S,3'S,4'R)-2'-carboxy-4'-(2-diazo-1-oxo-3, 3,3-trifluoropropyl)-3'-pyrrolidinyl acetate. Journal of Neurochemistry. 68: 1503-10. PMID 9084420 |
0.84 |
|
| 1997 |
Gill R, Lodge D. Pharmacology of AMPA antagonists and their role in neuroprotection. International Review of Neurobiology. 40: 197-232. PMID 8989622 |
0.84 |
|
| 1997 |
Bleisch TJ, Ornstein PL, Allen NK, Wright RA, Lodge D, Schoepp DD. Structure-activity studies of aryl-spaced decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists Bioorganic and Medicinal Chemistry Letters. 7: 1161-1166. DOI: 10.1016/S0960-894X(97)00185-6 |
0.84 |
|
| 1996 |
Bleakman D, Ballyk BA, Schoepp DD, Palmer AJ, Bath CP, Sharpe EF, Woolley ML, Bufton HR, Kamboj RK, Tarnawa I, Lodge D. Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles. Neuropharmacology. 35: 1689-702. PMID 9076748 DOI: 10.1016/S0028-3908(96)00156-6 |
0.84 |
|
| 1996 |
Lodge D, Bond A, O'Neill MJ, Hicks CA, Jones MG. Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies. Neuropharmacology. 35: 1681-8. PMID 9076747 DOI: 10.1016/S0028-3908(96)00155-4 |
0.84 |
|
| 1996 |
Nooney JM, Lodge D. The use of invertebrate peptide toxins to establish Ca2+ channel identity of CA3-CA1 neurotransmission in rat hippocampal slices. European Journal of Pharmacology. 306: 41-50. PMID 8813613 DOI: 10.1016/0014-2999(96)00195-1 |
0.84 |
|
| 1996 |
Fletcher EJ, Lodge D. New developments in the molecular pharmacology of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and kainate receptors. Pharmacology & Therapeutics. 70: 65-89. PMID 8804111 DOI: 10.1016/0163-7258(96)00014-9 |
0.84 |
|
| 1996 |
Fitzjohn SM, Irving AJ, Palmer MJ, Harvey J, Lodge D, Collingridge GL. Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices. Neuroscience Letters. 203: 211-3. PMID 8742030 DOI: 10.1016/0304-3940(96)12301-6 |
0.84 |
|
| 1996 |
Monn JA, Valli MJ, Johnson BG, Salhoff CR, Wright RA, Howe T, Bond A, Lodge D, Spangle LA, Paschal JW, Campbell JB, Griffey K, Tizzano JP, Schoepp DD. Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase. Journal of Medicinal Chemistry. 39: 2990-3000. PMID 8709133 DOI: 10.1021/jm9601765 |
0.84 |
|
| 1996 |
Day NC, Shaw PJ, McCormack AL, Craig PJ, Smith W, Beattie R, Williams TL, Ellis SB, Ince PG, Harpold MM, Lodge D, Volsen SG. Distribution of alpha 1A, alpha 1B and alpha 1E voltage-dependent calcium channel subunits in the human hippocampus and parahippocampal gyrus. Neuroscience. 71: 1013-24. PMID 8684604 DOI: 10.1016/0306-4522(95)00514-5 |
0.84 |
|
| 1996 |
Ornstein PL, Arnold MB, Allen NK, Bleisch T, Borromeo PS, Lugar CW, Leander JD, Lodge D, Schoepp DD. Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, absolute stereochemical preferences, and in vivo activity. Journal of Medicinal Chemistry. 39: 2232-44. PMID 8667366 DOI: 10.1021/jm950913h |
0.84 |
|
| 1996 |
Ornstein PL, Arnold MB, Allen NK, Bleisch T, Borromeo PS, Lugar CW, Leander JD, Lodge D, Schoepp DD. Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution. Journal of Medicinal Chemistry. 39: 2219-31. PMID 8667365 DOI: 10.1021/jm950912p |
0.84 |
|
| 1996 |
Lodge D, Bond A. Spinal glutamate receptors Pharmacochemistry Library. 24: 241-252. DOI: 10.1016/S0165-7208(96)80020-1 |
0.84 |
|
| 1996 |
Fitzjohn SM, Lodge D, Collingridge GL. Long-term depression of synaptic transmission induced by group in metabotropic glutamate receptor activation in the CA1 of young rat hippocampus Journal of Physiology Paris. 90: 410-4111. |
0.84 |
|
| 1996 |
Gill R, Lodge D. Pharmacology of AMPA antagonists and their role in neurophotection International Review of Neurobiology. 197-232. |
0.84 |
|
| 1995 |
Volsen SG, Day NC, McCormack AL, Smith W, Craig PJ, Beattie R, Ince PG, Shaw PJ, Ellis SB, Gillespie A. The expression of neuronal voltage-dependent calcium channels in human cerebellum. Brain Research. Molecular Brain Research. 34: 271-82. PMID 8750830 DOI: 10.1016/0169-328X(95)00234-J |
0.84 |
|
| 1995 |
Schoepp DD, Lodge D, Bleakman D, Leander JD, Tizzano JP, Wright RA, Palmer AJ, Salhoff CR, Ornstein PL. In vitro and in vivo antagonism of AMPA receptor activation by (3S, 4aR, 6R, 8aR)-6-[2-(1(2)H-tetrazole-5-yl) ethyl] decahydroisoquinoline-3-carboxylic acid. Neuropharmacology. 34: 1159-68. PMID 8532186 DOI: 10.1016/0028-3908(95)00099-R |
0.84 |
|
| 1995 |
Kingston AE, Burnett JP, Mayne NG, Lodge D. Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes. Neuropharmacology. 34: 887-94. PMID 8532170 DOI: 10.1016/0028-3908(95)00069-I |
0.84 |
|
| 1995 |
Bond A, Lodge D. Pharmacology of metabotropic glutamate receptor-mediated enhancement of responses to excitatory and inhibitory amino acids on rat spinal neurones in vivo. Neuropharmacology. 34: 1015-23. PMID 8532150 DOI: 10.1016/0028-3908(95)00046-9 |
0.84 |
|
| 1995 |
Ornstein PL, Arnold MB, Allen NK, Leander JD, Tizzano JP, Lodge D, Schoepp DD. (3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist. Journal of Medicinal Chemistry. 38: 4885-90. PMID 8523401 |
0.84 |
|
| 1995 |
Collingridge G, Lodge D. Editorial Neuropharmacology. 34: v. |
0.84 |
|
| 1994 |
Gill R, Lodge D. The neuroprotective effects of the decahydroisoquinoline, LY 215490; a novel AMPA antagonist in focal ischaemia. Neuropharmacology. 33: 1529-36. PMID 7760975 DOI: 10.1016/0028-3908(94)90126-0 |
0.84 |
|
| 1993 |
Ornstein PL, Arnold MB, Augenstein NK, Lodge D, Leander JD, Schoepp DD. (3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist. Journal of Medicinal Chemistry. 36: 2046-8. PMID 8393116 |
0.84 |
|
| 1993 |
Parsons CG, Gruner R, Rozental J, Millar J, Lodge D. Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan). Neuropharmacology. 32: 1337-50. PMID 8152525 DOI: 10.1016/0028-3908(93)90029-3 |
0.84 |
|
| 1993 |
Bowman D, Alexander S, Lodge D. Pharmacological characterisation of the calcium channels coupled to the plateau phase of KCl-induced intracellular free Ca2+ elevation in chicken and rat synaptosomes. Neuropharmacology. 32: 1195-202. PMID 8107973 DOI: 10.1016/0028-3908(93)90013-S |
0.84 |
|
| 1993 |
Palmer AJ, Lodge D. Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655. European Journal of Pharmacology. 244: 193-4. PMID 7679352 DOI: 10.1016/0922-4106(93)90027-7 |
0.84 |
|
| 1993 |
Ornstein PL, Arnold MB, Augenstein NK, Deeter JB, Leander JD, Lodge D, Calligaro DO, Schoepp DD. Unusual stereochemical preferences of decahydroisoquinoline-3-cargoxylic acid competitive NMDA antagonists Bioorganic and Medicinal Chemistry Letters. 3: 2067-2072. DOI: 10.1016/S0960-894X(01)81017-9 |
0.84 |
|
| 1993 |
Monn JA, Valli MJ, 1 RA, Schoepp DD, Leander JD, Lodge D. Synthesis and pharmacological characterization of l-trans-4-tetrazolylproline (ly300020): A novel systemically-active ampa receptor agonist Bioorganic and Medicinal Chemistry Letters. 3: 95-98. DOI: 10.1016/S0960-894X(00)80099-2 |
0.84 |
|
| 1993 |
Ornstein PL, Arnold MB, Evrard D, Leander JD, Lodge D, Schoepp DD. Tetrazole amino acids as competitive NMDA antagonists Bioorganic and Medicinal Chemistry Letters. 3: 43-48. DOI: 10.1016/S0960-894X(00)80089-X |
0.84 |
|
| 1993 |
Lodge D, Bond A. Pharmacology of ionotropic and metabotropic glutamate receptors European Neuropsychopharmacology. 3: 181-182. DOI: 10.1016/0924-977X(93)90013-C |
0.84 |
|
| 1992 |
Leander JD, Parli CJ, Potts B, Lodge D. Relation of plasma and brain concentrations of the anticonvulsant ameltolide to its pharmacologic effects. Epilepsia. 33: 696-704. PMID 1628587 DOI: 10.1111/j.1528-1157.1992.tb02350.x |
0.84 |
|
| 1992 |
Ornstein PL, Schoepp DD, Arnold MB, Augenstein NK, Lodge D, Millar JD, Chambers J, Campbell J, Paschal JW, Zimmerman DM. 6-substituted decahydroisoquinoline-3-carboxylic acids as potent and selective conformationally constrained NMDA receptor antagonists. Journal of Medicinal Chemistry. 35: 3547-60. PMID 1404235 |
0.84 |
|
| 1992 |
Ornstein PL, Schoepp DD, Arnold MB, Jones ND, Deeter JB, Lodge D, Leander JD. NMDA antagonist activity of (+/-)-(2SR,4RS)-4-(1H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer. Journal of Medicinal Chemistry. 35: 3111-5. PMID 1387167 |
0.84 |
|
| 1992 |
Zeman S, Lodge D. Pharmacological characterization of non-NMDA subtypes of glutamate receptor in the neonatal rat hemisected spinal cord in vitro. British Journal of Pharmacology. 106: 367-72. PMID 1382781 |
0.84 |
|
| 1992 |
McQuaid LA, Smith EC, South KK, Mitch CH, Schoepp DD, True RA, Calligaro DO, O'Malley PJ, Lodge D, Ornstein PL. Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones. Journal of Medicinal Chemistry. 35: 3319-24. PMID 1382133 |
0.84 |
|
| 1992 |
Palmer AJ, Zeman S, Lodge D. Methohexitone antagonises kainate and epileptiform activity in rat neocortical slices. European Journal of Pharmacology. 221: 205-9. PMID 1330621 DOI: 10.1016/0014-2999(92)90702-6 |
0.84 |
|
| 1992 |
McQuaid LA, Smith EC, Lodge D, Pralong E, Wikel JH, Calligaro DO, O'Malley PJ. 3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex. Journal of Medicinal Chemistry. 35: 3423-5. PMID 1326635 |
0.84 |
|
| 1991 |
Ornstein PL, Schoepp DD, Arnold MB, Leander JD, Lodge D, Paschal JW, Elzey T. 4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action. Journal of Medicinal Chemistry. 34: 90-7. PMID 1825117 |
0.84 |
|
| 1991 |
Schoepp DD, Smith CL, Lodge D, Millar JD, Leander JD, Sacaan AI, Lunn WH. D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist. European Journal of Pharmacology. 203: 237-43. PMID 1686860 DOI: 10.1016/0014-2999(91)90719-7 |
0.84 |
|
| 1990 |
Lodge D, Johnson KM. Noncompetitive excitatory amino acid receptor antagonists. Trends in Pharmacological Sciences. 11: 81-6. PMID 2156365 DOI: 10.1016/0165-6147(90)90323-Z |
0.84 |
|
| 1990 |
Ornstein PL, Schoepp DD, Leander JD, Wong T, Zimmerman DM, Lodge D. LY233053: a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist. Progress in Clinical and Biological Research. 361: 429-33. PMID 2149764 |
0.84 |
|
| 1990 |
Schoepp DD, Ornstein PL, Leander JD, Lodge D, Salhoff CR, Zeman S, Zimmerman DM. Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action. The Journal of Pharmacology and Experimental Therapeutics. 255: 1301-8. PMID 2148188 |
0.84 |
|
| 1990 |
Beart PM, Lodge D. Chronic administration of MK-801 and the NMDA receptor: further evidence for reduced sensitivity of the primary acceptor site from studies with the cortical wedge preparation. The Journal of Pharmacy and Pharmacology. 42: 354-5. PMID 1976785 |
0.84 |
|
| 1989 |
Fletcher EJ, Drew C, Lodge D, O'Shaughnessy CT. Efflux of rubidium in rat cortical synaptosomes is blocked by sigma and dextromethorphan binding site ligands. Neuropharmacology. 28: 661-6. PMID 2548109 DOI: 10.1016/0028-3908(89)90148-2 |
0.84 |
|
| 1988 |
Lodge D, Davies SN, Jones MG, Millar J, Manallack DT, Ornstein PL, Verberne AJ, Young N, Beart PM. A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists. British Journal of Pharmacology. 95: 957-65. PMID 2905186 |
0.84 |
|
| 1988 |
Church J, Zeman S, Lodge D. The neuroprotective action of ketamine and MK-801 after transient cerebral ischemia in rats. Anesthesiology. 69: 702-9. PMID 2847595 |
0.84 |
|
| 1985 |
Spence I, Drew C, Johnston GA, Lodge D. Acute effects of lead at central synapses in vitro. Brain Research. 333: 103-9. PMID 2986766 DOI: 10.1016/0006-8993(85)90129-5 |
0.84 |
|
| 1979 |
Curtis DR, Lodge D, McLennan H. The excitation and depression of spinal neurones by ibotenic acid. The Journal of Physiology. 291: 19-28. PMID 480204 |
0.84 |
|
| 1979 |
McLennan H, Lodge D. The antagonism of amino acid-induced excitation of spinal neurones in the cat. Brain Research. 169: 83-90. PMID 222399 DOI: 10.1016/0006-8993(79)90375-5 |
0.84 |
|
| 1977 |
Martin MR, Lodge D, Headley PM, Biscoe TJ. Pharmacological studies of facial motoneurones in the rat. European Journal of Pharmacology. 42: 291-8. PMID 856610 |
0.84 |
|
| 1977 |
Martin MR, Lodge D. Morphology of the facial nucleus of the rat. Brain Research. 123: 1-12. PMID 843907 DOI: 10.1016/0006-8993(77)90639-4 |
0.84 |
|
| 1977 |
Craig CR, Curtis DR, Lodge D. Dual effects of hemicholinium-3 at central cholinergic synapses. The Journal of Physiology. 264: 367-77. PMID 190385 |
0.84 |
|
| 1976 |
Biscoe TJ, Headley PM, Lodge D, Martin MR, Watkins JC. The sensitivity of rat spinal interneurones and renshaw cells to L-glutamate and L-aspartate. Experimental Brain Research. 26: 547-51. PMID 1010006 DOI: 10.1007/BF00238827 |
0.84 |
|
| 1976 |
Lodge D, Johnston GA, Stephenson AL. The uptake of GABA and beta-alanine in slices of cat and rat CNS tissue: regional differences in susceptibility to inhibitors. Journal of Neurochemistry. 27: 1569-70. PMID 1003233 |
0.84 |
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