Cherry C. Ho, Ph.D. - Related publications

Columbia University, New York, NY 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Leemans M, Galicia C, Deyaert E, Daems E, Krause L, Paesmans J, Pardon E, Steyaert J, Kortholt A, Sobott F, Klostermeier D, Versées W. Allosteric modulation of the GTPase activity of a bacterial LRRK2 homologue by conformation-specific Nanobodies. The Biochemical Journal. PMID 32167135 DOI: 10.1042/BCJ20190843   
2020 Yang H, Wang L, Zang C, Wang Y, Shang J, Zhang Z, Liu H, Bao X, Wang X, Zhang D. Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson's Disease Models. Frontiers in Neuroscience. 14: 45. PMID 32132891 DOI: 10.3389/fnins.2020.00045   
2020 Levy DR, Udgata A, Tourlomousis P, Symmons MF, Hopkins LJ, Bryant CE, Gay NJ. Parkinson's disease-associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages. The Journal of Biological Chemistry. PMID 32111741 DOI: 10.1074/jbc.RA119.011842   
2020 Vermilyea SC, Babinski A, Tran N, To S, Guthrie S, Kluss JH, Schmidt JK, Wiepz GJ, Meyer MG, Murphy ME, Cookson MR, Emborg ME, Golos TG. In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets. Scientific Reports. 10: 3447. PMID 32103062 DOI: 10.1038/s41598-020-60273-2   
2020 Marasco M, Berteotti A, Weyershaeuser J, Thorausch N, Sikorska J, Krausze J, Brandt HJ, Kirkpatrick J, Rios P, Schamel WW, Köhn M, Carlomagno T. Molecular mechanism of SHP2 activation by PD-1 stimulation. Science Advances. 6: eaay4458. PMID 32064351 DOI: 10.1126/sciadv.aay4458   
2020 Ding X, Ren F. Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-present). Expert Opinion On Therapeutic Patents. PMID 32049564 DOI: 10.1080/13543776.2020.1729354   
2020 Taylor M, Alessi DR. Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease. Current Opinion in Cell Biology. 63: 102-113. PMID 32036294 DOI: 10.1016/   
2020 Vieweg S, Mulholland K, Brauning B, Kacharia N, Lai YC, Toth R, Singh PK, Volpi I, Sattler M, Groll M, Itzen A, Muqit MMK. PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2 mediated phosphorylation at Threonine72. The Biochemical Journal. PMID 32227113 DOI: 10.1042/BCJ20190664   
2020 Wang Y, Wang P, Xu J. Phosphorylation: A Fast Switch For Checkpoint Signaling. Advances in Experimental Medicine and Biology. 1248: 347-398. PMID 32185718 DOI: 10.1007/978-981-15-3266-5_15   
2020 Kaleli HN, Ozer E, Kaya VO, Kutlu O. Protein Kinase C Isozymes and Autophagy during Neurodegenerative Disease Progression. Cells. 9. PMID 32120776 DOI: 10.3390/cells9030553   
2020 Franco-Iborra S, Plaza-Zabala A, Montpeyo M, Sebastian D, Vila M, Martinez-Vicente M. Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease. Autophagy. 1-18. PMID 32093570 DOI: 10.1080/15548627.2020.1728096   
2020 Lee KF, Tung SY, Teng CC, Shen CH, Hsieh MC, Huang CY, Lee KC, Lee LY, Chen WP, Chen CC, Huang WS, Kuo HC. Post-Treatment with Erinacine A, a Derived Diterpenoid of , Attenuates Neurotoxicity in MPTP Model of Parkinson's Disease. Antioxidants (Basel, Switzerland). 9. PMID 32033220 DOI: 10.3390/antiox9020137   
2020 Wang EJ, Gailey CD, Brautigan DL, Fu Z. Functional Alterations in Ciliogenesis-Associated Kinase 1 (CILK1) that Result from Mutations Linked to Juvenile Myoclonic Epilepsy. Cells. 9. PMID 32178256 DOI: 10.3390/cells9030694   
2020 Ogier JM, Nayagam BA, Lockhart PJ. ASK1 inhibition: a therapeutic strategy with multi-system benefits. Journal of Molecular Medicine (Berlin, Germany). PMID 32060587 DOI: 10.1007/s00109-020-01878-y   
2020 Fan X, Zhao Z, Wang D, Xiao J. Glycogen synthase kinase-3 as a key regulator of cognitive function. Acta Biochimica Et Biophysica Sinica. PMID 32147679 DOI: 10.1093/abbs/gmz156   
2020 Oxnard GR, Yang JC, Yu H, Kim SW, Saka H, Horn L, Goto K, Ohe Y, Mann H, Thress KS, Frigault MM, Vishwanathan K, Ghiorghiu D, Ramalingam SS, Ahn MJ. TATTON: a multi-arm, phase Ib trial of osimertinib combined with selumetinib, savolitinib, or durvalumab in EGFR-mutant lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 32139298 DOI: 10.1016/j.annonc.2020.01.013   
2020 Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V. Ataxia telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Haematologica. PMID 32029507 DOI: 10.3324/haematol.2019.234385   
2020 Yeung E, McFann S, Marsh L, Dufresne E, Filippi S, Harrington HA, Shvartsman SY, Wühr M. Inference of Multisite Phosphorylation Rate Constants and Their Modulation by Pathogenic Mutations. Current Biology : Cb. PMID 32059766 DOI: 10.1016/j.cub.2019.12.052   
2020 Waschbüsch D, Purlyte E, Pal P, McGrath E, Alessi DR, Khan AR. Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2. Structure (London, England : 1993). PMID 32017888 DOI: 10.1016/j.str.2020.01.005   
2020 Yang Y, Liu J, Yin C, Vespoli LS, Ge D, Huang Y, Feng B, Xu G, Manhães AMEA, Dou S, Criswell C, Shan L, Wang X, He P. RNAi-based screen reveals concerted functions of MEKK2 and CRCK3 in plant cell death regulation. Plant Physiology. PMID 32165446 DOI: 10.1104/pp.19.01555   
2020 Duan Q, Ye J, Shi M, Chen W, Zhu F. Research advances in the molecular functions and relevant diseases of TAOKs, novel STE20 kinase family members. Current Pharmaceutical Design. PMID 32013821 DOI: 10.2174/1381612826666200203115458   
2020 Li G, Qi W, Li X, Zhao J, Luo M, Chen J. Recent Advances in c-Jun N-terminal Kinase (JNK) Inhibitors. Current Medicinal Chemistry. PMID 32039671 DOI: 10.2174/0929867327666200210144114   
2020 Wu H, Wei S, Huang Y, Chen L, Wang Y, Wu X, Zhang Z, Pei Y, Wang D. Aβ monomer induces phosphorylation of Tau at Ser-214 through β2AR-PKA-JNK signaling pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32067279 DOI: 10.1096/fj.201902230RR   
2020 Pennuto M, Pandey UB, Polanco MJ. Insulin-like growth factor 1 signaling in motor neuron and polyglutamine diseases: From molecular pathogenesis to therapeutic perspectives. Frontiers in Neuroendocrinology. 100821. PMID 32006533 DOI: 10.1016/j.yfrne.2020.100821   
2020 Seabright AP, Fine NHF, Barlow JP, Lord SO, Musa I, Gray A, Bryant JA, Banzhaf M, Lavery GG, Hardie DG, Hodson DJ, Philp A, Lai YC. AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32201986 DOI: 10.1096/fj.201903051R   
2020 Yang DM, Huang CC, Chang YF. Combinatorial Roles of Mitochondria and cGMP/PKG Pathway in the Generation of Neuronal Free Zn2+ under the Presence of Nitric Oxide. Journal of the Chinese Medical Association : Jcma. PMID 32101891 DOI: 10.1097/JCMA.0000000000000280   
2020 Angira D, Shaik A, Thiruvenkatam V. Structural and strategic landscape of PIKK protein family and their inhibitors: an overview. Frontiers in Bioscience (Landmark Edition). 25: 1538-1567. PMID 32114444   
2020 Zhang X, Matsuda M, Yaegashi N, Nabe T, Kitatani K. Regulation of Necroptosis by Phospholipids and Sphingolipids. Cells. 9. PMID 32151027 DOI: 10.3390/cells9030627   
2020 Jeong S, Sohn YK, Choi Y, Park J, Kim HS. A regulatory SH2 domain-targeting protein binder effectively inhibits the activity of Bruton's tyrosine kinase and its drug-resistant variants. Biochemical and Biophysical Research Communications. PMID 32192770 DOI: 10.1016/j.bbrc.2020.03.006   
2020 Yi SA, Lee J, Park SK, Kim JY, Park JW, Lee MG, Nam KH, Park JH, Oh H, Kim S, Han J, Kim BK, Jo DG, Han JW. Fermented ginseng extract, BST204, disturbs adipogenesis of mesenchymal stem cells through inhibition of S6 kinase 1 signaling. Journal of Ginseng Research. 44: 58-66. PMID 32148390 DOI: 10.1016/j.jgr.2018.08.002   
2020 Spengler K, Kryeziu N, Große S, Mosig AS, Heller R. VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1. Cells. 9. PMID 32168879 DOI: 10.3390/cells9030687   
2020 Han XR, Chen L, Wei Y, Yu W, Chen Y, Zhang C, Jiao B, Shi T, Sun L, Zhang C, Xu Y, Lee MR, Luo Y, Plewe MB, Wang J. Discovery of Selective Small Molecule Degraders of BRAF-V600E. Journal of Medicinal Chemistry. PMID 32223235 DOI: 10.1021/acs.jmedchem.9b02083   
2020 Saleh A, Sabbir MG, Aghanoori MR, Smith DR, Roy Chowdhury SK, Tessler L, Brown J, Gedarevich E, Kassahun MZ, Frizzi K, Calcutt NA, Fernyhough P. Muscarinic Toxin 7 Signals Via Ca/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration. Molecular Neurobiology. PMID 32198698 DOI: 10.1007/s12035-020-01900-x   
2020 Zhang F, Geng L, Deng J, Huang L, Zhong H, Xin S, Fasoyin OE, Wang S. The MAP kinase AflSlt2 modulates aflatoxin biosynthesis and peanut infection in the fungus Aspergillus flavus. International Journal of Food Microbiology. 322: 108576. PMID 32240921 DOI: 10.1016/j.ijfoodmicro.2020.108576   
2020 Wu PK, Hong SK, Chen W, Becker AE, Gundry RL, Lin CW, Shao H, Gestwicki JE, Park JI. Mortalin (HSPA9) facilitates -mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. Science Signaling. 13. PMID 32156782 DOI: 10.1126/scisignal.aay1478   
2020 Ovchinnikov DA, Withey SL, Leeson HC, Lei UW, Sundarrajan A, Junday K, Pewarchuk M, Yeo AJ, Kijas AW, Lavin MF, Wolvetang EJ. Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses. Human Molecular Genetics. PMID 32037450 DOI: 10.1093/hmg/ddaa023   
2020 Fan S, Price T, Huang W, Plue M, Warren J, Sundaramoorthy P, Paul B, Feinberg D, MacIver N, Chao N, Sipkins D, Kang Y. PINK1-Dependent Mitophagy Regulates the Migration and Homing of Multiple Myeloma Cells via the MOB1B-Mediated Hippo-YAP/TAZ Pathway. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1900860. PMID 32154065 DOI: 10.1002/advs.201900860   
2020 De S, Campbell C, Venkitaraman AR, Esposito A. Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage. Cell Reports. PMID 32075732 DOI: 10.1016/j.celrep.2020.01.074   
2020 Bradley JR, Wang J, Pacey S, Warren AY, Pober JS, Al-Lamki RS. Tumor necrosis factor receptor-2 signaling pathways promote survival of cancer stem-like CD133 cells in clear cell renal carcinoma. Faseb Bioadvances. 2: 126-144. PMID 32123862 DOI: 10.1096/fba.2019-00071   
2020 Shen D, Chen W, Zhu J, Wu G, Shen R, Xi M, Sun H. Therapeutic potential of targeting SHP2 in human developmental disorders and cancers. European Journal of Medicinal Chemistry. 190: 112117. PMID 32061959 DOI: 10.1016/j.ejmech.2020.112117   
2020 Tanaka K, Ito Y, Kajiwara K, Nada S, Okada M. Ubiquitination of Src promotes its secretion via small extracellular vesicles. Biochemical and Biophysical Research Communications. PMID 32085898 DOI: 10.1016/j.bbrc.2020.02.057   
2020 Held MA, Greenfest-Allen E, Su S, Stoeckert CJ, Stokes MP, Wojchowski DM. Phospho-PTM proteomic discovery of novel EPO- modulated kinases and phosphatases, including PTPN18 as a positive regulator of EPOR/JAK2 Signaling. Cellular Signalling. 109554. PMID 32027948 DOI: 10.1016/j.cellsig.2020.109554   
2020 Huo J, Xu S, Lam KP. ASK1 Mediates Nur77 Expression in T-Cell Receptor Mediated Thymocyte Apoptosis. Cells. 9. PMID 32121597 DOI: 10.3390/cells9030585   
2020 Xu P, Shen P, Yu B, Xu X, Ge R, Cheng X, Chen Q, Bian J, Li Z, Wang J. Janus kinases (JAKs): The efficient therapeutic targets for autoimmune diseases and myeloproliferative disorders. European Journal of Medicinal Chemistry. 192: 112155. PMID 32120325 DOI: 10.1016/j.ejmech.2020.112155   
2020 Dohmen M, Krieg S, Agalaridis G, Zhu X, Shehata SN, Pfeiffenberger E, Amelang J, Bütepage M, Buerova E, Pfaff CM, Chanda D, Geley S, Preisinger C, Sakamoto K, Lüscher B, et al. AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy. Nature Communications. 11: 1032. PMID 32098961 DOI: 10.1038/s41467-020-14812-0   
2020 Mattos EC, Silva LP, Valero C, de Castro PA, Dos Reis TF, Ribeiro LFC, Marten MR, Silva-Rocha R, Westmann C, da Silva CHTP, Taft CA, Al-Furaiji N, Bromley M, Mortensen UH, Benz JP, et al. The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance. Mbio. 11. PMID 32019798 DOI: 10.1128/mBio.02962-19   
2020 Jones LM, Melgar K, Bolanos L, Hueneman K, Walker MM, Jiang JK, Wilson KM, Zhang X, Shen J, Jiang F, Sutter P, Wang A, Xu X, Tawa GJ, Hoyt SB, et al. Targeting AML-associated FLT3 mutations with a type I kinase inhibitor. The Journal of Clinical Investigation. PMID 32149729 DOI: 10.1172/JCI127907   
2020 Yang C, Mai H, Peng J, Zhou B, Hou J, Jiang D. STAT4: an immunoregulator contributing to diverse human diseases. International Journal of Biological Sciences. 16: 1575-1585. PMID 32226303 DOI: 10.7150/ijbs.41852   
2020 van Alphen C, Cloos J, Beekhof R, Cucchi DGJ, Piersma SR, Knol JC, Henneman AA, Pham TV, van Meerloo J, Ossenkoppele GJ, Verheul HM, Janssen JJ, Jimenez CR. Phosphotyrosine-based phosphoproteomics for target identification and drug response prediction in AML cell lines. Molecular & Cellular Proteomics : McP. PMID 32102969 DOI: 10.1074/mcp.RA119.001504   
2020 Horn M, Denzel SI, Srinivasan B, Allmeroth K, Schiffer I, Karthikaisamy V, Miethe S, Breuer P, Antebi A, Denzel MS. Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response. Iscience. 23: 100887. PMID 32086012 DOI: 10.1016/j.isci.2020.100887