Gary Lynch - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
learning and memory
Website:
https://www.faculty.uci.edu/profile.cfm?faculty_id=2658

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lopez AJ, Hemstedt TJ, Jia Y, Hwang PH, Campbell RR, Kwapis JL, White AO, Chitnis O, Scarfone VM, Matheos DP, Lynch G, Wood MA. Epigenetic regulation of immediate-early gene Nr4a2/Nurr1 in the medial habenula during reinstatement of cocaine-associated behavior. Neuropharmacology. PMID 30998946 DOI: 10.1016/j.neuropharm.2019.04.016  0.76
2018 Gunn BG, Sanchez GA, Lynch G, Baram TZ, Chen Y. Hyper-diversity of CRH interneurons in mouse hippocampus. Brain Structure & Function. PMID 30456559 DOI: 10.1007/s00429-018-1793-z  0.4
2018 Wang W, Le AA, Hou B, Lauterborn JC, Cox CD, Levin ER, Lynch G, Gall CM. Memory-Related Synaptic Plasticity Is Sexually Dimorphic in Rodent Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 7935-7951. PMID 30209204 DOI: 10.1523/JNEUROSCI.0801-18.2018  1
2018 Sun J, Liu Y, Jia Y, Hao X, Lin WJ, Tran J, Lynch G, Baudry M, Bi X. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. Elife. 7. PMID 30020076 DOI: 10.7554/eLife.37993  1
2018 Merrill CB, Basit A, Armirotti A, Jia Y, Gall CM, Lynch G, Piomelli D. Author Correction: Patch clamp-assisted single neuron lipidomics. Scientific Reports. 8: 6772. PMID 29691427 DOI: 10.1038/s41598-018-24605-7  1
2018 López AJ, Jia Y, White AO, Kwapis JL, Espinoza M, Hwang P, Campbell R, Alaghband Y, Chitnis O, Matheos DP, Lynch G, Wood MA. Medial habenula cholinergic signaling regulates cocaine-associated relapse-like behavior. Addiction Biology. PMID 29430793 DOI: 10.1111/adb.12605  0.76
2017 Purcell R, Lynch G, Gall C, Johnson S, Zhong S, Stephen MR, Cook J, Garman RH, Jortner B, Bolon B, Radin D, Lippa A. Brain Vacuolation Resulting from Administration of the Type II Ampakine CX717 is an Artifact Related to Molecular Structure and Chemical Reaction with Tissue Fixative Agents. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29253237 DOI: 10.1093/toxsci/kfx277  0.44
2017 Wang W, Cox BM, Jia Y, Le AA, Cox CD, Jung KM, Hou B, Piomelli D, Gall CM, Lynch G. Treating a novel plasticity defect rescues episodic memory in Fragile X model mice. Molecular Psychiatry. PMID 29133950 DOI: 10.1038/mp.2017.221  1
2017 Cox CD, Palmer LC, Pham DT, Trieu BH, Gall CM, Lynch G. Experiential learning in rodents: past experience enables rapid learning and localized encoding in hippocampus. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 569-579. PMID 29038218 DOI: 10.1101/lm.045559.117  1
2017 Merrill CB, Basit A, Armirotti A, Jia Y, Gall CM, Lynch G, Piomelli D. Patch clamp-assisted single neuron lipidomics. Scientific Reports. 7: 5318. PMID 28706218 DOI: 10.1038/s41598-017-05607-3  1
2017 Wang W, Jia Y, Pham DT, Palmer LC, Jung KM, Cox CD, Rumbaugh G, Piomelli D, Gall CM, Lynch G. Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus. Cerebral Cortex (New York, N.Y. : 1991). 1-14. PMID 28520937 DOI: 10.1093/cercor/bhx126  1
2017 Vogel Ciernia A, Kramár EA, Matheos DP, Havekes R, Hemstedt TJ, Magnan CN, Sakata K, Tran A, Azzawi S, Lopez A, Dang R, Wang W, Trieu B, Tong J, Barrett RM, ... ... Lynch G, et al. Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 199-209. PMID 28416631 DOI: 10.1101/lm.044602.116  0.92
2016 Prieto GA, Trieu BH, Dang CT, Bilousova T, Gylys KH, Berchtold NC, Lynch G, Cotman CW. Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986924 DOI: 10.1523/JNEUROSCI.2774-16.2016  0.68
2016 Chen Y, Molet J, Lauterborn JC, Trieu BH, Bolton JL, Patterson KP, Gall CM, Lynch G, Baram TZ. Converging, Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11295-11307. PMID 27807170 DOI: 10.1523/JNEUROSCI.2542-16.2016  1
2016 Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. Eneuro. 3. PMID 27517090 DOI: 10.1523/ENEURO.0160-16.2016  1
2016 Wang W, Kantorovich S, Babayan AH, Hou B, Gall CM, Lynch G. Estrogen's Effects on Excitatory Synaptic Transmission Entail Integrin and TrkB Transactivation and Depend upon ß1 Integrin Function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27272766 DOI: 10.1038/npp.2016.83  1
2016 Lauterborn JC, Kramár EA, Rice JD, Babayan AH, Cox CD, Karsten CA, Gall CM, Lynch G. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cerebral Cortex (New York, N.Y. : 1991). PMID 27073215 DOI: 10.1093/cercor/bhw088  1
2016 Lauterborn JC, Palmer LC, Jia Y, Pham DT, Hou B, Wang W, Trieu BH, Cox CD, Kantorovich S, Gall CM, Lynch G. Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged Rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1636-46. PMID 26843645 DOI: 10.1523/JNEUROSCI.3157-15.2016  1
2015 Hjelm BE, Rollins B, Mamdani F, Lauterborn JC, Kirov G, Lynch G, Gall CM, Sequeira A, Vawter MP. Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia. Molecular Neuropsychiatry. 1: 201-219. PMID 26550561 DOI: 10.1159/000441252  1
2015 Trieu BH, Kramár EA, Cox CD, Jia Y, Wang W, Gall CM, Lynch G. Pronounced differences in signal processing and synaptic plasticity between piriform-hippocampal network stages: a prominent role for adenosine. The Journal of Physiology. 593: 2889-907. PMID 25902928 DOI: 10.1113/JP270398  1
2014 Lynch G, Baudry M. Brain and memory: Old arguments and new perspectives. Brain Research. PMID 25557403 DOI: 10.1016/j.brainres.2014.12.052  1
2014 Lynch G, Kramár EA, Gall CM. Protein synthesis and consolidation of memory-related synaptic changes. Brain Research. PMID 25485773 DOI: 10.1016/j.brainres.2014.11.060  1
2014 Posner MI, Tang YY, Lynch G. Mechanisms of white matter change induced by meditation training. Frontiers in Psychology. 5: 1220. PMID 25386155 DOI: 10.3389/fpsyg.2014.01220  1
2014 Seese RR, Wang K, Yao YQ, Lynch G, Gall CM. Spaced training rescues memory and ERK1/2 signaling in fragile X syndrome model mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 16907-12. PMID 25385607 DOI: 10.1073/pnas.1413335111  1
2014 Sejnowski TJ, Poizner H, Lynch G, Gepshtein S, Greenspan RJ. Prospective Optimization. Proceedings of the Ieee. Institute of Electrical and Electronics Engineers. 102. PMID 25328167 DOI: 10.1109/JPROC.2014.2314297  1
2014 Ozkan ED, Creson TK, Kramár EA, Rojas C, Seese RR, Babyan AH, Shi Y, Lucero R, Xu X, Noebels JL, Miller CA, Lynch G, Rumbaugh G. Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons. Neuron. 82: 1317-33. PMID 24945774 DOI: 10.1016/j.neuron.2014.05.015  1
2014 Lynch G, Cox CD, Gall CM. Pharmacological enhancement of memory or cognition in normal subjects. Frontiers in Systems Neuroscience. 8: 90. PMID 24904313 DOI: 10.3389/fnsys.2014.00090  1
2014 Cox CD, Rex CS, Palmer LC, Babayan AH, Pham DT, Corwin SD, Trieu BH, Gall CM, Lynch G. A map of LTP-related synaptic changes in dorsal hippocampus following unsupervised learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3033-41. PMID 24553943 DOI: 10.1523/JNEUROSCI.4159-13.2014  1
2014 Riazifar H, Jia Y, Chen J, Lynch G, Huang T. Chemically induced specification of retinal ganglion cells from human embryonic and induced pluripotent stem cells. Stem Cells Translational Medicine. 3: 424-32. PMID 24493857 DOI: 10.5966/sctm.2013-0147  1
2014 Seese RR, Maske AR, Lynch G, Gall CM. Long-term memory deficits are associated with elevated synaptic ERK1/2 activation and reversed by mGluR5 antagonism in an animal model of autism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1664-73. PMID 24448645 DOI: 10.1038/npp.2014.13  1
2014 Fields RD, Araque A, Johansen-Berg H, Lim SS, Lynch G, Nave KA, Nedergaard M, Perez R, Sejnowski T, Wake H. Glial biology in learning and cognition. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 20: 426-31. PMID 24122821 DOI: 10.1177/1073858413504465  1
2013 Snider J, Plank M, Lynch G, Halgren E, Poizner H. Human cortical θ during free exploration encodes space and predicts subsequent memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15056-68. PMID 24048836 DOI: 10.1523/JNEUROSCI.0268-13.2013  1
2013 Lynch G, Gall CM. Mechanism based approaches for rescuing and enhancing cognition. Frontiers in Neuroscience. 7: 143. PMID 23966908 DOI: 10.3389/fnins.2013.00143  1
2013 Seese RR, Chen LY, Cox CD, Schulz D, Babayan AH, Bunney WE, Henn FA, Gall CM, Lynch G. Synaptic abnormalities in the infralimbic cortex of a model of congenital depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13441-8. PMID 23946402 DOI: 10.1523/JNEUROSCI.2434-13.2013  1
2013 Vogel-Ciernia A, Matheos DP, Barrett RM, Kramár EA, Azzawi S, Chen Y, Magnan CN, Zeller M, Sylvain A, Haettig J, Jia Y, Tran A, Dang R, Post RJ, Chabrier M, ... ... Lynch G, et al. The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nature Neuroscience. 16: 552-61. PMID 23525042 DOI: 10.1038/nn.3359  1
2013 Lynch G, Kramár EA, Babayan AH, Rumbaugh G, Gall CM. Differences between synaptic plasticity thresholds result in new timing rules for maximizing long-term potentiation. Neuropharmacology. 64: 27-36. PMID 22820276 DOI: 10.1016/j.neuropharm.2012.07.006  1
2012 Tong L, Prieto GA, Kramár EA, Smith ED, Cribbs DH, Lynch G, Cotman CW. Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17714-24. PMID 23223292 DOI: 10.1523/JNEUROSCI.1253-12.2012  1
2012 Babayan AH, Kramár EA, Barrett RM, Jafari M, Häettig J, Chen LY, Rex CS, Lauterborn JC, Wood MA, Gall CM, Lynch G. Integrin dynamics produce a delayed stage of long-term potentiation and memory consolidation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12854-61. PMID 22973009 DOI: 10.1523/JNEUROSCI.2024-12.2012  1
2012 Seese RR, Babayan AH, Katz AM, Cox CD, Lauterborn JC, Lynch G, Gall CM. LTP induction translocates cortactin at distant synapses in wild-type but not Fmr1 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7403-13. PMID 22623686 DOI: 10.1523/JNEUROSCI.0968-12.2012  1
2012 Baudry M, Kramar E, Xu X, Zadran H, Moreno S, Lynch G, Gall C, Bi X. Ampakines promote spine actin polymerization, long-term potentiation, and learning in a mouse model of Angelman syndrome. Neurobiology of Disease. 47: 210-5. PMID 22525571 DOI: 10.1016/j.nbd.2012.04.002  1
2012 Kramár EA, Babayan AH, Gavin CF, Cox CD, Jafari M, Gall CM, Rumbaugh G, Lynch G. Synaptic evidence for the efficacy of spaced learning. Proceedings of the National Academy of Sciences of the United States of America. 109: 5121-6. PMID 22411798 DOI: 10.1073/pnas.1120700109  1
2012 Kramár EA, Chen LY, Lauterborn JC, Simmons DA, Gall CM, Lynch G. BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats. Neurobiology of Aging. 33: 708-19. PMID 20674095 DOI: 10.1016/j.neurobiolaging.2010.06.008  1
2011 Barrett RM, Malvaez M, Kramar E, Matheos DP, Arrizon A, Cabrera SM, Lynch G, Greene RW, Wood MA. Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1545-56. PMID 21508930 DOI: 10.1038/npp.2011.61  1
2011 Clarkson AN, Overman JJ, Zhong S, Mueller R, Lynch G, Carmichael ST. AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3766-75. PMID 21389231 DOI: 10.1523/JNEUROSCI.5780-10.2011  1
2011 Lynch G, Palmer LC, Gall CM. The likelihood of cognitive enhancement. Pharmacology, Biochemistry, and Behavior. 99: 116-29. PMID 21215768 DOI: 10.1016/j.pbb.2010.12.024  1
2011 Baudry M, Bi X, Gall C, Lynch G. The biochemistry of memory: The 26year journey of a 'new and specific hypothesis'. Neurobiology of Learning and Memory. 95: 125-33. PMID 21134478 DOI: 10.1016/j.nlm.2010.11.015  1
2011 Simmons DA, Mehta RA, Lauterborn JC, Gall CM, Lynch G. Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice. Neurobiology of Disease. 41: 436-44. PMID 20977939 DOI: 10.1016/j.nbd.2010.10.015  1
2010 Chen LY, Rex CS, Pham DT, Lynch G, Gall CM. BDNF signaling during learning is regionally differentiated within hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15097-101. PMID 21068315 DOI: 10.1523/JNEUROSCI.3549-10.2010  1
2010 Jia Y, Gall CM, Lynch G. Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14440-5. PMID 20980601 DOI: 10.1523/JNEUROSCI.3310-10.2010  1
2010 Ivy AS, Rex CS, Chen Y, Dubé C, Maras PM, Grigoriadis DE, Gall CM, Lynch G, Baram TZ. Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13005-15. PMID 20881118 DOI: 10.1523/JNEUROSCI.1784-10.2010  1
2010 Rex CS, Gavin CF, Rubio MD, Kramar EA, Chen LY, Jia Y, Huganir RL, Muzyczka N, Gall CM, Miller CA, Lynch G, Rumbaugh G. Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation. Neuron. 67: 603-17. PMID 20797537 DOI: 10.1016/j.neuron.2010.07.016  1
2010 Chen LY, Rex CS, Babayan AH, Kramár EA, Lynch G, Gall CM, Lauterborn JC. Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10977-84. PMID 20720104 DOI: 10.1523/JNEUROSCI.1077-10.2010  1
2010 Chen Y, Rex CS, Rice CJ, Dubé CM, Gall CM, Lynch G, Baram TZ. Correlated memory defects and hippocampal dendritic spine loss after acute stress involve corticotropin-releasing hormone signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 13123-8. PMID 20615973 DOI: 10.1073/pnas.1003825107  1
2010 Palmer L, Lynch G. Neuroscience. A Kantian view of space. Science (New York, N.Y.). 328: 1487-8. PMID 20558692 DOI: 10.1126/science.1191527  1
2010 Chen LY, Rex CS, Sanaiha Y, Lynch G, Gall CM. Learning induces neurotrophin signaling at hippocampal synapses. Proceedings of the National Academy of Sciences of the United States of America. 107: 7030-5. PMID 20356829 DOI: 10.1073/pnas.0912973107  1
2009 Kramár EA, Chen LY, Rex CS, Gall CM, Lynch G. Estrogen's Place in the Family of Synaptic Modulators. Molecular and Cellular Pharmacology. 1: 258-262. PMID 20419049 DOI: 10.4255/mcpharmacol.09.31  1
2009 Rex CS, Colgin LL, Jia Y, Casale M, Yanagihara TK, Debenedetti M, Gall CM, Kramar EA, Lynch G. Origins of an intrinsic hippocampal EEG pattern. Plos One. 4: e7761. PMID 19907647 DOI: 10.1371/journal.pone.0007761  1
2009 Kramár EA, Chen LY, Brandon NJ, Rex CS, Liu F, Gall CM, Lynch G. Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12982-93. PMID 19828812 DOI: 10.1523/JNEUROSCI.3059-09.2009  1
2009 Rex CS, Chen LY, Sharma A, Liu J, Babayan AH, Gall CM, Lynch G. Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation. The Journal of Cell Biology. 186: 85-97. PMID 19596849 DOI: 10.1083/jcb.200901084  1
2009 Simmons DA, Rex CS, Palmer L, Pandyarajan V, Fedulov V, Gall CM, Lynch G. Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 4906-11. PMID 19264961 DOI: 10.1073/pnas.0811228106  1
2008 Casale MS, Baratto M, Cervera C, Gallamini M, Lynch G, Gjini K, Boutros NN. Auditory evoked potential abnormalities in cluster headache. Neuroreport. 19: 1633-6. PMID 18845943 DOI: 10.1097/WNR.0b013e328314e0dd  1
2008 Lynch G, Rex CS, Chen LY, Gall CM. The substrates of memory: defects, treatments, and enhancement. European Journal of Pharmacology. 585: 2-13. PMID 18374328 DOI: 10.1016/j.ejphar.2007.11.082  1
2007 Lauterborn JC, Rex CS, Kramár E, Chen LY, Pandyarajan V, Lynch G, Gall CM. Brain-derived neurotrophic factor rescues synaptic plasticity in a mouse model of fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10685-94. PMID 17913902 DOI: 10.1523/JNEUROSCI.2624-07.2007  1
2007 Fedulov V, Rex CS, Simmons DA, Palmer L, Gall CM, Lynch G. Evidence that long-term potentiation occurs within individual hippocampal synapses during learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8031-9. PMID 17652593 DOI: 10.1523/JNEUROSCI.2003-07.2007  1
2007 Simmons DA, Casale M, Alcon B, Pham N, Narayan N, Lynch G. Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease. Glia. 55: 1074-84. PMID 17551926 DOI: 10.1002/glia.20526  1
2007 Chen LY, Rex CS, Casale MS, Gall CM, Lynch G. Changes in synaptic morphology accompany actin signaling during LTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5363-72. PMID 17507558 DOI: 10.1523/JNEUROSCI.0164-07.2007  1
2007 Lynch G, Kramar EA, Rex CS, Jia Y, Chappas D, Gall CM, Simmons DA. Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4424-34. PMID 17442827 DOI: 10.1523/JNEUROSCI.5113-06.2007  1
2007 Rex CS, Lin CY, Kramár EA, Chen LY, Gall CM, Lynch G. Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3017-29. PMID 17360925 DOI: 10.1523/JNEUROSCI.4037-06.2007  1
2007 Lynch G, Rex CS, Gall CM. LTP consolidation: substrates, explanatory power, and functional significance. Neuropharmacology. 52: 12-23. PMID 16949110 DOI: 10.1016/j.neuropharm.2006.07.027  1
2006 Lynch G, Rex CS, Gall CM. Synaptic plasticity in early aging. Ageing Research Reviews. 5: 255-80. PMID 16935034 DOI: 10.1016/j.arr.2006.03.008  1
2006 Lynch G, Gall CM. Ampakines and the threefold path to cognitive enhancement. Trends in Neurosciences. 29: 554-62. PMID 16890999 DOI: 10.1016/j.tins.2006.07.007  1
2006 Rex CS, Lauterborn JC, Lin CY, Kramár EA, Rogers GA, Gall CM, Lynch G. Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor. Journal of Neurophysiology. 96: 677-85. PMID 16707719 DOI: 10.1152/jn.00336.2006  1
2006 Kramár EA, Lin B, Rex CS, Gall CM, Lynch G. Integrin-driven actin polymerization consolidates long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 103: 5579-84. PMID 16567651 DOI: 10.1073/pnas.0601354103  1
2006 Lynch G. Glutamate-based therapeutic approaches: ampakines. Current Opinion in Pharmacology. 6: 82-8. PMID 16361116 DOI: 10.1016/j.coph.2005.09.005  1
2005 Brunson KL, Kramár E, Lin B, Chen Y, Colgin LL, Yanagihara TK, Lynch G, Baram TZ. Mechanisms of late-onset cognitive decline after early-life stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9328-38. PMID 16221841 DOI: 10.1523/JNEUROSCI.2281-05.2005  1
2005 Bi X, Liu J, Yao Y, Baudry M, Lynch G. Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain. The American Journal of Pathology. 167: 1081-92. PMID 16192643 DOI: 10.1016/S0002-9440(10)61197-2  1
2005 Lin CY, Lynch G, Gall CM. AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling. Journal of Neurochemistry. 94: 531-46. PMID 16000124 DOI: 10.1111/j.1471-4159.2005.03203.x  1
2005 Rex CS, Kramár EA, Colgin LL, Lin B, Gall CM, Lynch G. Long-term potentiation is impaired in middle-aged rats: regional specificity and reversal by adenosine receptor antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5956-66. PMID 15976084 DOI: 10.1523/JNEUROSCI.0880-05.2005  1
2005 Colgin LL, Jia Y, Sabatier JM, Lynch G. Blockade of NMDA receptors enhances spontaneous sharp waves in rat hippocampal slices. Neuroscience Letters. 385: 46-51. PMID 15927372 DOI: 10.1016/j.neulet.2005.05.005  1
2005 Bernard-Trifilo JA, Kramár EA, Torp R, Lin CY, Pineda EA, Lynch G, Gall CM. Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology. Journal of Neurochemistry. 93: 834-49. PMID 15857387 DOI: 10.1111/j.1471-4159.2005.03062.x  1
2005 Lin B, Kramár EA, Bi X, Brucher FA, Gall CM, Lynch G. Theta stimulation polymerizes actin in dendritic spines of hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2062-9. PMID 15728846 DOI: 10.1523/JNEUROSCI.4283-04.2005  1
2005 Jourdi H, Yanagihara T, Martinez U, Bi X, Lynch G, Baudry M. Effects of positive AMPA receptor modulators on calpain-mediated spectrin degradation in cultured hippocampal slices. Neurochemistry International. 46: 31-40. PMID 15567513 DOI: 10.1016/j.neuint.2004.07.002  1
2004 Bi X, Baudry M, Liu J, Yao Y, Fu L, Brucher F, Lynch G. Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia. The Journal of Biological Chemistry. 279: 48238-45. PMID 15364922 DOI: 10.1074/jbc.M405442200  1
2004 Colgin LL, Kubota D, Brucher FA, Jia Y, Branyan E, Gall CM, Lynch G. Spontaneous waves in the dentate gyrus of slices from the ventral hippocampus. Journal of Neurophysiology. 92: 3385-98. PMID 15282260 DOI: 10.1152/jn.00478.2004  1
2004 Gall CM, Lynch G. Integrins, synaptic plasticity and epileptogenesis. Advances in Experimental Medicine and Biology. 548: 12-33. PMID 15250583  1
2004 Colgin LL, Kubota D, Jia Y, Rex CS, Lynch G. Long-term potentiation is impaired in rat hippocampal slices that produce spontaneous sharp waves. The Journal of Physiology. 558: 953-61. PMID 15194734 DOI: 10.1113/jphysiol.2004.068080  1
2004 Kramár EA, Lin B, Lin CY, Arai AC, Gall CM, Lynch G. A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5151-61. PMID 15175384 DOI: 10.1523/JNEUROSCI.0800-04.2004  1
2004 Díaz-Cintra S, Yong A, Aguilar A, Bi X, Lynch G, Ribak CE. Ultrastructural analysis of hippocampal pyramidal neurons from apolipoprotein E-deficient mice treated with a cathepsin inhibitor. Journal of Neurocytology. 33: 37-48. PMID 15173631 DOI: 10.1023/B:NEUR.0000029647.41374.98  1
2004 Lynch G. AMPA receptor modulators as cognitive enhancers. Current Opinion in Pharmacology. 4: 4-11. PMID 15018832 DOI: 10.1016/j.coph.2003.09.009  1
2003 Lynch G, Bi X. Lysosomes and brain aging in mammals. Neurochemical Research. 28: 1725-34. PMID 14584826 DOI: 10.1023/A:1026069223763  1
2003 Bi X, Head E, Cotman CW, Lynch G. Spatial patterns of mammalian brain aging: distribution of cathepsin D-immunoreactive cell bodies and dystrophic dendrites in aging dogs resembles that in Alzheimer's disease. The Journal of Comparative Neurology. 464: 371-81. PMID 12900930 DOI: 10.1002/cne.10795  1
2003 Lauterborn JC, Truong GS, Baudry M, Bi X, Lynch G, Gall CM. Chronic elevation of brain-derived neurotrophic factor by ampakines. The Journal of Pharmacology and Experimental Therapeutics. 307: 297-305. PMID 12893840 DOI: 10.1124/jpet.103.053694  1
2003 Colgin LL, Kramár EA, Gall CM, Lynch G. Septal modulation of excitatory transmission in hippocampus. Journal of Neurophysiology. 90: 2358-66. PMID 12840078 DOI: 10.1152/jn.00262.2003  1
2003 Lin B, Arai AC, Lynch G, Gall CM. Integrins regulate NMDA receptor-mediated synaptic currents. Journal of Neurophysiology. 89: 2874-8. PMID 12740418 DOI: 10.1152/jn.00783.2002  1
2003 Colgin LL, Kubota D, Lynch G. Cholinergic plasticity in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 100: 2872-7. PMID 12591947 DOI: 10.1073/pnas.0530289100  1
2003 Kramár EA, Bernard JA, Gall CM, Lynch G. Integrins modulate fast excitatory transmission at hippocampal synapses. The Journal of Biological Chemistry. 278: 10722-30. PMID 12524441 DOI: 10.1074/jbc.M210225200  1
2003 Kubota D, Colgin LL, Casale M, Brucher FA, Lynch G. Endogenous waves in hippocampal slices. Journal of Neurophysiology. 89: 81-9. PMID 12522161 DOI: 10.1152/jn.00542.2002  1
2002 Shimono K, Baudry M, Ho L, Taketani M, Lynch G. Long-term recording of LTP in cultured hippocampal slices. Neural Plasticity. 9: 249-54. PMID 12959154 DOI: 10.1155/NP.2002.249  1
2002 Arai AC, Xia YF, Rogers G, Lynch G, Kessler M. Benzamide-type AMPA receptor modulators form two subfamilies with distinct modes of action. The Journal of Pharmacology and Experimental Therapeutics. 303: 1075-85. PMID 12438530 DOI: 10.1124/jpet.102.040360  1
2002 Lin B, Colgin LL, Brücher FA, Arai AC, Lynch G. Interactions between recording technique and AMPA receptor modulators. Brain Research. 955: 164-73. PMID 12419533 DOI: 10.1016/S0006-8993(02)03429-7  1
2002 Lynch G. Memory enhancement: the search for mechanism-based drugs. Nature Neuroscience. 5: 1035-8. PMID 12403980 DOI: 10.1038/nn935  1
2002 Benvenuto J, Jin Y, Casale M, Lynch G, Granger R. Identification of diagnostic evoked response potential segments in Alzheimer's disease. Experimental Neurology. 176: 269-76. PMID 12359169 DOI: 10.1006/exnr.2002.7930  1
2002 Shimono K, Kubota D, Brucher F, Taketani M, Lynch G. Asymmetrical distribution of the Schaffer projections within the apical dendrites of hippocampal field CA1. Brain Research. 950: 279-87. PMID 12231254 DOI: 10.1016/S0006-8993(02)03052-4  1
2002 Arai AC, Xia YF, Kessler M, Phillips D, Chamberlin R, Granger R, Lynch G. Effects of 5'-alkyl-benzothiadiazides on (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor biophysics and synaptic responses. Molecular Pharmacology. 62: 566-77. PMID 12181433 DOI: 10.1124/mol.62.3.566  1
2002 Lin B, Brücher FA, Colgin LL, Lynch G. Long-term potentiation alters the modulator pharmacology of AMPA-type glutamate receptors. Journal of Neurophysiology. 87: 2790-800. PMID 12037181  1
2002 Phillips D, Sonnenberg J, Arai AC, Vaswani R, Krutzik PO, Kleisli T, Kessler M, Granger R, Lynch G, Richard Chamberlin A. 5'-alkyl-benzothiadiazides: a new subgroup of AMPA receptor modulators with improved affinity. Bioorganic & Medicinal Chemistry. 10: 1229-48. PMID 11886787 DOI: 10.1016/S0968-0896(01)00405-9  1
2000 Arai AC, Kessler M, Rogers G, Lynch G. Effects of the potent ampakine CX614 on hippocampal and recombinant AMPA receptors: Interactions with cyclothiazide and GYKI 52466 Molecular Pharmacology. 58: 802-813. PMID 10999951  1
2000 Lauterborn JC, Lynch G, Vanderklish P, Arai A, Gall CM. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8-21. PMID 10627576  1
1999 Johnson SA, Luu NT, Herbst TA, Knapp R, Lutz D, Arai A, Rogers GA, Lynch G. Synergistic interactions between ampakines and antipsychotic drugs. The Journal of Pharmacology and Experimental Therapeutics. 289: 392-7. PMID 10087029  0.8
1998 Arai A, Lynch G. AMPA receptor desensitization modulates synaptic responses induced by repetitive afferent stimulation in hippocampal slices. Brain Research. 799: 235-42. PMID 9675296  0.52
1998 Arai A, Lynch G. The waveform of synaptic transmission at hippocampal synapses is not determined by AMPA receptor desensitization. Brain Research. 799: 230-4. PMID 9675293  0.52
1997 Davis CM, Moskovitz B, Nguyen MA, Tran BB, Arai A, Lynch G, Granger R. A profile of the behavioral changes produced by facilitation of AMPA-type glutamate receptors. Psychopharmacology. 133: 161-7. PMID 9342782  0.52
1997 Hennegriff M, Arai A, Kessler M, Vanderklish P, Mutneja MS, Rogers G, Neve RL, Lynch G. Stable expression of recombinant AMPA receptor subunits: binding affinities and effects of allosteric modulators. Journal of Neurochemistry. 68: 2424-34. PMID 9166736  1
1996 Arai A, Kessler M, Ambros-Ingerson J, Quan A, Yigiter E, Rogers G, Lynch G. Effects of a centrally active benzoylpyrrolidine drug on AMPA receptor kinetics Neuroscience. 75: 573-585. PMID 8931020 DOI: 10.1016/0306-4522(96)00263-1  1
1996 Arai A, Guidotti A, Costa E, Lynch G. Effect of the AMPA receptor modulator IDRA 21 on LTP in hippocampal slices. Neuroreport. 7: 2211-5. PMID 8930991  0.52
1996 Arai A, Kessler M, Rogers G, Lynch G. Effects of a memory-enhancing drug on DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor currents and synaptic transmission in hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 278: 627-38. PMID 8768713  0.52
1996 Arai A, Lynch G. Response to repetitive stimulation of AMPA receptors in patches excised from fields CA1 and CA3 of the hippocampus. Brain Research. 716: 202-6. PMID 8738240 DOI: 10.1016/0006-8993(96)00030-3  0.52
1996 Kessler M, Arai A, Quan A, Lynch G. Effect of cyclothiazide on binding properties of AMPA-type glutamate receptors: Lack of competition between cyclothiazide and GYKI 52466 Molecular Pharmacology. 49: 123-131. PMID 8569697  1
1995 Arai A, Silberg J, Lynch G. Differences in the refractory properties of two distinct inhibitory circuitries in field CA1 of the hippocampus. Brain Research. 704: 298-306. PMID 8788926  0.52
1995 Arai A, Silberg J, Kessler M, Lynch G. Effect of thiocyanate on AMPA receptor mediated responses in excised patches and hippocampal slices. Neuroscience. 66: 815-27. PMID 7544449  0.52
1995 Vanderklish P, Saido TC, Gall C, Arai A, Lynch G. Proteolysis of spectrin by calpain accompanies theta-burst stimulation in cultured hippocampal slices. Brain Research. Molecular Brain Research. 32: 25-35. PMID 7494460  0.52
1994 del Cerro S, Arai A, Kessler M, Bahr BA, Vanderklish P, Rivera S, Lynch G. Stimulation of NMDA receptors activates calpain in cultured hippocampal slices. Neuroscience Letters. 167: 149-52. PMID 8177514 DOI: 10.1016/0304-3940(94)91049-9  1
1994 Arai A, Black J, Lynch G. Origins of the variations in long-term potentiation between synapses in the basal versus apical dendrites of hippocampal neurons. Hippocampus. 4: 1-9. PMID 8061748 DOI: 10.1002/hipo.450040103  0.52
1994 Arai A, Kessler M, Xiao P, Ambros-Ingerson J, Rogers G, Lynch G. A centrally active drug that modulates AMPA receptor gated currents. Brain Research. 638: 343-6. PMID 7911064  0.52
1992 Arai A, Lynch G. Antagonists of the Platelet-activating Factor Receptor Block Long-term Potentiation in Hippocampal Slices. The European Journal of Neuroscience. 4: 411-419. PMID 12106349  0.52
1992 Arai A, Lynch G. Factors regulating the magnitude of long-term potentiation induced by theta pattern stimulation. Brain Research. 598: 173-84. PMID 1486479  0.52
1992 Vanderklish P, Neve R, Bahr BA, Arai A, Hennegriff M, Larson J, Lynch G. Translational suppression of a glutamate receptor subunit impairs long-term potentiation. Synapse (New York, N.Y.). 12: 333-7. PMID 1465743 DOI: 10.1002/syn.890120410  1
1992 Muller D, Arai A, Lynch G. Factors governing the potentiation of NMDA receptor-mediated responses in hippocampus. Hippocampus. 2: 29-38. PMID 1364046 DOI: 10.1002/hipo.450020105  0.52
1991 Arai A, Vanderklish P, Kessler M, Lee K, Lynch G. A brief period of hypoxia causes proteolysis of cytoskeletal proteins in hippocampal slices. Brain Research. 555: 276-80. PMID 1933340  0.52
1991 Lee KS, Frank S, Vanderklish P, Arai A, Lynch G. Inhibition of proteolysis protects hippocampal neurons from ischemia. Proceedings of the National Academy of Sciences of the United States of America. 88: 7233-7. PMID 1871130  0.52
1991 Kessler M, Arai A, Vanderklish P, Lynch G. Failure to detect changes in AMPA receptor binding after long-term potentiation. Brain Research. 560: 337-41. PMID 1684732  0.52
1990 Arai A, Larson J, Lynch G. Anoxia reveals a vulnerable period in the development of long-term potentiation. Brain Research. 511: 353-7. PMID 2334854  0.52
1990 Arai A, Kessler M, Lee K, Lynch G. Calpain inhibitors improve the recovery of synaptic transmission from hypoxia in hippocampal slices. Brain Research. 532: 63-8. PMID 2178038  0.52
1990 Lynch G, Kessler M, Arai A, Larson J. The nature and causes of hippocampal long-term potentiation. Progress in Brain Research. 83: 233-50. PMID 2168058  0.52
1990 Arai A, Baudry M, Staubli U, Lynch G, Gall C. Induction of ornithine decarboxylase by subseizure stimulation in the hippocampus in vivo. Brain Research. Molecular Brain Research. 7: 167-9. PMID 2160044  1
1990 Arai A, Kessler M, Lynch G. The effects of adenosine on the development of long-term potentiation. Neuroscience Letters. 119: 41-4. PMID 2097583  0.52
1990 del Cerro S, Arai A, Lynch G. Inhibition of long-term potentiation by an antagonist of platelet-activating factor receptors. Behavioral and Neural Biology. 54: 213-7. PMID 1964041  0.52
Show low-probability matches.