Asa Hatami, Ph.D. - Related publications

Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Fertilization, Alzheimer disease
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Pulina MV, Hopkins M, Haroutunian V, Greengard P, Bustos V. C99 selectively accumulates in vulnerable neurons in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31677937 DOI: 10.1016/j.jalz.2019.09.002   
2019 Michelson D, Grundman M, Magnuson K, Fisher R, Levenson JM, Aisen P, Marek K, Gray M, Hefti F. Randomized, Placebo Controlled Trial of NPT088, A Phage-Derived, Amyloid-Targeted Treatment for Alzheimer's Disease. The Journal of Prevention of Alzheimer's Disease. 6: 228-231. PMID 31686093 DOI: 10.14283/jpad.2019.37   
2019 Šimić G, Španić E, Langer Horvat L, Hof PR. Blood-brain barrier and innate immunity in the pathogenesis of Alzheimer's disease. Progress in Molecular Biology and Translational Science. 168: 99-145. PMID 31699331 DOI: 10.1016/bs.pmbts.2019.06.003   
2019 Shin WS, Di J, Cao Q, Li B, Seidler PM, Murray KA, Bitan G, Jiang L. Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimer's Research & Therapy. 11: 86. PMID 31627745 DOI: 10.1186/s13195-019-0541-9   
2019 Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS. Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau. Elife. 8. PMID 31612856 DOI: 10.7554/eLife.46924   
2019 Aliyan A, Cook NP, Martí AA. Interrogating Amyloid Aggregates using Fluorescent Probes. Chemical Reviews. PMID 31675223 DOI: 10.1021/acs.chemrev.9b00404   
2019 Sho M, Ichiyanagi N, Imaizumi K, Ishikawa M, Morimoto S, Watanabe H, Okano H. A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition. Neuroscience Research. PMID 31606373 DOI: 10.1016/j.neures.2019.10.006   
2019 Ahmad SS, Khan S, Kamal MA, Wasi U. The structure and function of α, β and γ-Secretase as therapeutic target enzymes into the development of Alzheimer's disease: A review. Cns & Neurological Disorders Drug Targets. PMID 31608840 DOI: 10.2174/1871527318666191011145941   
2019 Ren B, Zhang Y, Zhang M, Liu Y, Zhang D, Gong X, Feng Z, Tang J, Chang Y, Zheng J. Fundamentals of cross-seeding of amyloid proteins: an introduction. Journal of Materials Chemistry. B. PMID 31647489 DOI: 10.1039/c9tb01871a   
2019 Lu TT, Wan C, Yang W, Cai Z. Role of Cdk5 in Amyloid-beta Pathology of Alzheimer's Disease. Current Alzheimer Research. PMID 31820699 DOI: 10.2174/1567205016666191210094435   
2019 Moon SP, Balana AT, Galesic A, Rakshit A, Pratt MR. Ubiquitination can change the structure of the α-synuclein amyloid fiber in a site selective fashion. The Journal of Organic Chemistry. PMID 31809571 DOI: 10.1021/acs.joc.9b02641   
2019 Singh A, Agarwal S, Singh S. Age related neurodegenerative Alzheimer's disease: Usage of traditional herbs in therapeutics. Neuroscience Letters. 134679. PMID 31816333 DOI: 10.1016/j.neulet.2019.134679   
2019 Vander Zanden CM, Chi EY. Passive immunotherapies targeting amyloid beta and tau oligomers in Alzheimer's disease. Journal of Pharmaceutical Sciences. PMID 31647950 DOI: 10.1016/j.xphs.2019.10.024   
2019 Metaxas A, Thygesen C, Kempf SJ, Anzalone M, Vaitheeswaran R, Petersen S, Landau AM, Audrain H, Teeling JL, Darvesh S, Brooks DJ, Larsen MR, Finsen B. Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease. Scientific Reports. 9: 15758. PMID 31673052 DOI: 10.1038/s41598-019-52357-5   
2019 Shin WS, Di J, Murray KA, Sun C, Li B, Bitan G, Jiang L. Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation. Frontiers in Molecular Neuroscience. 12: 268. PMID 31787880 DOI: 10.3389/fnmol.2019.00268   
2019 Wessels AM, Tariot PN, Zimmer JA, Selzler KJ, Bragg SM, Andersen SW, Landry J, Krull JH, Downing AM, Willis BA, Shcherbinin S, Mullen J, Barker P, Schumi J, Shering C, et al. Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease: The AMARANTH and DAYBREAK-ALZ Randomized Clinical Trials. Jama Neurology. PMID 31764959 DOI: 10.1001/jamaneurol.2019.3988   
2019 Zhang H, Zheng Y. [β Amyloid Hypothesis in Alzheimer's Disease:Pathogenesis,Prevention,and Management]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 41: 702-708. PMID 31699204 DOI: 10.3881/j.issn.1000-503X.10875   
2019 Thal DR, Ronisz A, Tousseyn T, Rijal Upadhaya A, Balakrishnan K, Vandenberghe R, Vandenbulcke M, von Arnim CAF, Otto M, Beach TG, Lilja J, Heurling K, Chakrabarty A, Ismail A, Buckley C, et al. Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia. Acta Neuropathologica Communications. 7: 178. PMID 31727169 DOI: 10.1186/s40478-019-0837-9   
2019 Iqbal K, Liu F, Gong C, Dai C, Hu W. Why delay in effective treatment for Alzheimer's disease and related conditions. Progress in Molecular Biology and Translational Science. 168: 243-256. PMID 31699318 DOI: 10.1016/bs.pmbts.2019.08.002   
2019 Zhou R, Yang G, Shi Y. Macromolecular complex in recognition and proteolysis of amyloid precursor protein in Alzheimer's disease. Current Opinion in Structural Biology. 61: 1-8. PMID 31629221 DOI: 10.1016/   
2019 Paasila PJ, Davies DS, Kril JJ, Goldsbury C, Sutherland GT. The relationship between the morphological subtypes of microglia and Alzheimer's disease neuropathology. Brain Pathology (Zurich, Switzerland). 29: 726-740. PMID 30803086 DOI: 10.1111/bpa.12717   
2019 Jokar S, Khazaei S, Behnammanesh H, Shamloo A, Erfani M, Beiki D, Bavi O. Recent advances in the design and applications of amyloid-β peptide aggregation inhibitors for Alzheimer's disease therapy. Biophysical Reviews. PMID 31713720 DOI: 10.1007/s12551-019-00606-2   
2019 Kuhn AJ, Raskatov JA. Using mirror-image peptides to enhance robustness and reproducibility in studying the amyloid β-protein. Progress in Molecular Biology and Translational Science. 168: 57-67. PMID 31699327 DOI: 10.1016/bs.pmbts.2019.05.010   
2019 Levin J. Parkinsonism in genetic and sporadic Alzheimer's disease. International Review of Neurobiology. 149: 237-247. PMID 31779814 DOI: 10.1016/bs.irn.2019.10.005   
2019 Jacob RS, Anoop A, Maji SK. Protein Nanofibrils as Storage Forms of Peptide Drugs and Hormones. Advances in Experimental Medicine and Biology. 1174: 265-290. PMID 31713202 DOI: 10.1007/978-981-13-9791-2_8   
2019 Bailey DK, Kosman DJ. Is brain iron trafficking part of the physiology of the amyloid precursor protein? Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 31578640 DOI: 10.1007/s00775-019-01684-z   
2019 Choi H, Kim HJ, Yang J, Chae S, Lee W, Chung S, Kim J, Choi H, Song H, Lee CK, Jun JH, Lee YJ, Lee K, Kim S, Sim HR, et al. Acetylation changes tau interactome to degrade tau in Alzheimer's disease animal and organoid models. Aging Cell. e13081. PMID 31763743 DOI: 10.1111/acel.13081   
2019 García-González L, Pilat D, Baranger K, Rivera S. Emerging Alternative Proteinases in APP Metabolism and Alzheimer's Disease Pathogenesis: A Focus on MT1-MMP and MT5-MMP. Frontiers in Aging Neuroscience. 11: 244. PMID 31607898 DOI: 10.3389/fnagi.2019.00244   
2019 Howard R, Zubko O, Bradley R, Harper E, Pank L, O'Brien J, Fox C, Tabet N, Livingston G, Bentham P, McShane R, Burns A, Ritchie C, Reeves S, Lovestone S, ... , et al. Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial. Jama Neurology. PMID 31738372 DOI: 10.1001/jamaneurol.2019.3762   
2019 Kollmer M, Close W, Funk L, Rasmussen J, Bsoul A, Schierhorn A, Schmidt M, Sigurdson CJ, Jucker M, Fändrich M. Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue. Nature Communications. 10: 4760. PMID 31664019 DOI: 10.1038/s41467-019-12683-8   
2019 Li TR, Wang XN, Sheng C, Li YX, Li FZ, Sun Y, Han Y. Extracellular vesicles as an emerging tool for the early detection of Alzheimer's disease. Mechanisms of Ageing and Development. 111175. PMID 31678325 DOI: 10.1016/j.mad.2019.111175   
2019 Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, et al. NLRP3 inflammasome activation drives tau pathology. Nature. PMID 31748742 DOI: 10.1038/s41586-019-1769-z   
2019 Liu PP, Xie Y, Meng XY, Kang JS. History and progress of hypotheses and clinical trials for Alzheimer's disease. Signal Transduction and Targeted Therapy. 4: 29. PMID 31637009 DOI: 10.1038/s41392-019-0063-8   
2019 Stephen TL, Tamagnini F, Piegsa J, Sung K, Harvey J, Oliver-Evans A, Murray TK, Ahmed Z, Hutton ML, Randall A, O'Neill MJ, Jackson JS. Imbalance in the response of pre- and post-synaptic components to amyloidopathy. Scientific Reports. 9: 14837. PMID 31619689 DOI: 10.1038/s41598-019-50781-1   
2019 Leong YQ, Ng KY, Chye SM, Ling APK, Koh RY. Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death. Metabolic Brain Disease. PMID 31811496 DOI: 10.1007/s11011-019-00516-y   
2019 Wang X, Wang Y, Zhu Y, Yan L, Zhao L. Neuroprotective Effect of S-trans, Trans-farnesylthiosalicylic Acid via Inhibition of RAS/ERK Pathway for the Treatment of Alzheimer's Disease. Drug Design, Development and Therapy. 13: 4053-4063. PMID 31819374 DOI: 10.2147/DDDT.S233283   
2019 Wang X, Wang Y, Zhu Y, Yan L, Zhao L. Neuroprotective Effect of S-trans, Trans-farnesylthiosalicylic Acid via Inhibition of RAS/ERK Pathway for the Treatment of Alzheimer's Disease. Drug Design, Development and Therapy. 13: 4053-4063. PMID 31819374 DOI: 10.2147/DDDT.S233283   
2019 Huynh TV, Wang C, Tran AC, Tabor GT, Mahan TE, Francis CM, Finn MB, Spellman R, Manis M, Tanzi RE, Ulrich JD, Holtzman DM. Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model. Molecular Neurodegeneration. 14: 37. PMID 31623648 DOI: 10.1186/s13024-019-0337-1   
2019 van der Kant R, Goldstein LSB, Ossenkoppele R. Amyloid-β-independent regulators of tau pathology in Alzheimer disease. Nature Reviews. Neuroscience. PMID 31780819 DOI: 10.1038/s41583-019-0240-3   
2019 Meinen BA, Gadkari VV, Stull F, Ruotolo BT, Bardwell JCA. SERF engages in a fuzzy complex that accelerates primary nucleation of amyloid proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 31659041 DOI: 10.1073/pnas.1913316116   
2019 Wu H, Wu ZG, Shi WJ, Gao H, Wu HH, Bian F, Jia PP, Hou YN. Effects of progesterone on glucose uptake in neurons of Alzheimer's disease animals and cell models. Life Sciences. 116979. PMID 31647947 DOI: 10.1016/j.lfs.2019.116979   
2019 Pande M, Srivastava R. Molecular and clinical insights into protein misfolding and associated amyloidosis. European Journal of Medicinal Chemistry. 184: 111753. PMID 31622853 DOI: 10.1016/j.ejmech.2019.111753   
2019 Hong G, Zeng P, Li N, Cai H, Guo Y, Li X, Li K, Li H. A Qualitative Analysis Based on Relative Expression Orderings Identifies Transcriptional Subgroups for Alzheimer's Disease. Current Alzheimer Research. PMID 31763973 DOI: 10.2174/1567205016666191122125035   
2019 Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunology and Cell Biology. PMID 31654430 DOI: 10.1111/imcb.12301   
2019 Fuchsberger T, Yuste R, Martinez-Bellver S, Blanco-Gandia MC, Torres-Cuevas I, Blasco-Serra A, Arango R, Miñarro J, Rodríguez-Arias M, Teruel-Marti V, Lloret A, Viña J. Oral Monosodium Glutamate Administration Causes Early Onset of Alzheimer's Disease-Like Pathophysiology in APP/PS1 Mice. Journal of Alzheimer's Disease : Jad. PMID 31658055 DOI: 10.3233/JAD-190274   
2019 Arboleda-Velasquez JF, Lopera F, O'Hare M, Delgado-Tirado S, Marino C, Chmielewska N, Saez-Torres KL, Amarnani D, Schultz AP, Sperling RA, Leyton-Cifuentes D, Chen K, Baena A, Aguillon D, Rios-Romenets S, et al. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nature Medicine. PMID 31686034 DOI: 10.1038/s41591-019-0611-3   
2019 Burnham SC, Coloma PM, Li QX, Collins S, Savage G, Laws S, Doecke J, Maruff P, Martins RN, Ames D, Rowe CC, Masters CL, Villemagne VL. Application of the NIA-AA Research Framework: Towards a Biological Definition of Alzheimer's Disease Using Cerebrospinal Fluid Biomarkers in the AIBL Study. The Journal of Prevention of Alzheimer's Disease. 6: 248-255. PMID 31686097 DOI: 10.14283/jpad.2019.25   
2019 Wood A, Chau E, Yang Y, Kim JR. A KLVFFAE-Derived Peptide Probe for Detection of Alpha-Synuclein Fibrils. Applied Biochemistry and Biotechnology. PMID 31776941 DOI: 10.1007/s12010-019-03197-6   
2019 Španić E, Langer Horvat L, Hof PR, Šimić G. Role of Microglial Cells in Alzheimer's Disease Tau Propagation. Frontiers in Aging Neuroscience. 11: 271. PMID 31636558 DOI: 10.3389/fnagi.2019.00271   
2019 Sheu JJ, Yang LY, Renuka Sanotra M, Wang ST, Lu HT, Sook Yee Kam R, Hsu IU, Kao SH, Lee CK, Chang-Cheng Shieh J, Lin YF. Reduction of AHI1 in the serum of Taiwanese with probable Alzheimer's disease. Clinical Biochemistry. PMID 31786207 DOI: 10.1016/j.clinbiochem.2019.11.011