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Ke Ruan, Ph.D. - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
macromolecular structure and dynamics in solution
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lv M, Gao J, Li M, Ma R, Li F, Liu Y, Liu M, Zhang J, Yao X, Wu J, Shi Y, Tang Y, Pan Y, Zhang ZY, Ruan K. Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1. The Journal of Physical Chemistry Letters. PMID 32885980 DOI: 10.1021/Acs.Jpclett.0C02039  0.391
2019 Nshogoza G, Liu Y, Gao J, Liu M, Moududee SA, Ma R, Li F, Zhang J, Wu J, Shi Y, Ruan K. NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43. International Journal of Molecular Sciences. 20. PMID 31262091 DOI: 10.3390/Ijms20133230  0.356
2019 Zhang J, Guo Q, Gao J, Xu C, Zhang B, Li M, She J, Shi Y, Zhang Z, Ruan K, Wu J. Structural insight into the unique dsDNA binding topology of the human ORC2 wing helix domain. The Febs Journal. PMID 30963726 DOI: 10.1111/Febs.14844  0.361
2018 Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, ... ... Ruan K, et al. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin. Nature Chemical Biology. PMID 30120361 DOI: 10.1038/S41589-018-0115-3  0.321
2018 Xu D, Ma R, Zhang J, Liu Z, Wu B, Peng J, Zhai Y, Gong Q, Shi Y, Wu J, Wu Q, Zhang Z, Ruan K. Dynamic Nature of CTCF Tandem 11 Zinc Fingers in Multivalent Recognition of DNA as Revealed by NMR Spectroscopy. The Journal of Physical Chemistry Letters. PMID 29965776 DOI: 10.1021/Acs.Jpclett.8B01440  0.343
2018 Xu D, Li B, Gao J, Liu Z, Niu X, Nshogoza G, Zhang J, Wu J, Su XC, He W, Ma R, Yang D, Ruan K. Ligand Proton Pseudocontact Shifts Determined from Paramagnetic Relaxation Dispersion in the Limit of NMR Intermediate Exchange. The Journal of Physical Chemistry Letters. PMID 29864276 DOI: 10.1021/Acs.Jpclett.8B01443  0.394
2018 Zhong X, Xiang H, Wang T, Zhong L, Ming D, Nie L, Cao F, Li B, Cao J, Mu D, Ruan K, Wang L, Wang D. A Novel Inhibitor of the New Antibiotic Resistance (ARE) Protein OptrA. Chemical Biology & Drug Design. PMID 29671947 DOI: 10.1111/Cbdd.13311  0.323
2018 Liu J, Zhang S, Liu M, Liu Y, Nshogoza G, Gao J, Ma R, Yang Y, Wu J, Zhang J, Li F, Ruan K. Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit. The Febs Journal. PMID 29645362 DOI: 10.1111/Febs.14469  0.342
2017 Gao J, Liang E, Ma R, Li F, Liu Y, Liu J, Jiang L, Li C, Dai H, Wu J, Su X, He W, Ruan K. Use of Fluorine Pseudocontact Shifts to Characterize the Protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange. Angewandte Chemie (International Ed. in English). PMID 28846825 DOI: 10.1002/Anie.201707114  0.381
2017 Xu L, Cheng A, Huang M, Zhang J, Jiang Y, Wang C, Li F, Bao H, Gao J, Wang N, Liu J, Wu J, Wong CCL, Ruan K. Structural insight into CBP bromodomain-mediated recognition of acetylated histone H3K56ac. The Febs Journal. PMID 28815970 DOI: 10.1111/Febs.14198  0.305
2017 Liu J, Li F, Bao H, Jiang Y, Zhang S, Ma R, Gao J, Wu J, Ruan K. The Polar Warhead of a TRIM24 Bromodomain Inhibitor Rearranges a Water-Mediated Interaction Network. The Febs Journal. PMID 28207202 DOI: 10.1111/Febs.14041  0.306
2016 Ma R, Wang P, Wu J, Ruan K. Process of Fragment-Based Lead Discovery-A Perspective from NMR. Molecules (Basel, Switzerland). 21. PMID 27438813 DOI: 10.3390/Molecules21070854  0.402
2016 Wei Q, Chen J, Mi J, Zhang J, Ruan K, Wu J. NMR Backbone Assignment of Large Proteins by Using (13) Cα -Only Triple-Resonance Experiments. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27276173 DOI: 10.1002/Chem.201601871  0.417
2016 Wang N, Li F, Bao H, Li J, Wu J, Ruan K. NMR fragment screening hit induces plasticity of BRD7/9 bromodomains. Chembiochem : a European Journal of Chemical Biology. PMID 27194508 DOI: 10.1002/Cbic.201600184  0.337
2016 Ma RS, Li QF, Wang AD, Zhang JH, Liu ZJ, Wu JH, Su XC, Ruan K. Determination of pseudocontact shifts of low-populated excited states by NMR chemical exchange saturation transfer. Physical Chemistry Chemical Physics : Pccp. PMID 27001533 DOI: 10.1039/C6Cp01127F  0.332
2016 Wei Q, Chen J, Mi J, Zhang J, Ruan K, Wu J. Frontispiece: NMR Backbone Assignment of Large Proteins by Using 13Cα-Only Triple-Resonance Experiments Chemistry - a European Journal. 22. DOI: 10.1002/Chem.201682862  0.348
2014 Liu Z, Li F, Ruan K, Zhang J, Mei Y, Wu J, Shi Y. Structural and functional insights into the human Börjeson-Forssman-Lehmann syndrome-associated protein PHF6. The Journal of Biological Chemistry. 289: 10069-83. PMID 24554700 DOI: 10.1074/Jbc.M113.535351  0.301
2014 Gao J, Ma R, Wang W, Wang N, Sasaki R, Snyderman D, Wu J, Ruan K. Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complex. Plos One. 9: e88098. PMID 24505392 DOI: 10.1371/Journal.Pone.0088098  0.304
2013 Dai YN, Chi CB, Zhou K, Cheng W, Jiang YL, Ren YM, Ruan K, Chen Y, Zhou CZ. Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase. The Journal of Biological Chemistry. 288: 22985-92. PMID 23818518 DOI: 10.1074/Jbc.M113.480335  0.36
2013 He C, Pillai SS, Taglini F, Li F, Ruan K, Zhang J, Wu J, Shi Y, Bayne EH. Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification. Proceedings of the National Academy of Sciences of the United States of America. 110: E1879-88. PMID 23613586 DOI: 10.1073/Pnas.1212155110  0.346
2009 Ruan K, Yang S, Van Sant KA, Likos JJ. Application of Hadamard spectroscopy to automated structure verification in high-throughput NMR. Magnetic Resonance in Chemistry : Mrc. 47: 693-700. PMID 19496061 DOI: 10.1002/Mrc.2459  0.325
2008 Ruan K, Briggman KB, Tolman JR. De novo determination of internuclear vector orientations from residual dipolar couplings measured in three independent alignment media. Journal of Biomolecular Nmr. 41: 61-76. PMID 18478335 DOI: 10.1007/S10858-008-9240-8  0.542
2008 Wu J, Feng M, Ruan KH. Assembling NMR structures for the intracellular loops of the human thromboxane A2 receptor: implication of the G protein-coupling pocket. Archives of Biochemistry and Biophysics. 470: 73-82. PMID 18073117 DOI: 10.1016/J.Abb.2007.11.016  0.308
2006 Gebel EB, Ruan K, Tolman JR, Shortle D. Multiple alignment tensors from a denatured protein. Journal of the American Chemical Society. 128: 9310-1. PMID 16848448 DOI: 10.1021/Ja0627693  0.709
2006 Tolman JR, Ruan K. NMR residual dipolar couplings as probes of biomolecular dynamics. Chemical Reviews. 106: 1720-36. PMID 16683751 DOI: 10.1021/Cr040429Z  0.678
2005 Ruan K, Tolman JR. Composite alignment media for the measurement of independent sets of NMR residual dipolar couplings. Journal of the American Chemical Society. 127: 15032-3. PMID 16248635 DOI: 10.1021/Ja055520E  0.692
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