| Year |
Citation |
Score |
| 2018 |
Koo Y, Hawkins BT, Yun Y. Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening. Scientific Reports. 8: 2841. PMID 29434277 DOI: 10.1038/s41598-018-20876-2 |
0.508 |
|
| 2017 |
Izawa Y, Gu YH, Osada T, Kanazawa M, Hawkins BT, Koziol JA, Papayannopoulou T, Spatz M, Del Zoppo GJ. β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17722108. PMID 28787238 DOI: 10.1177/0271678X17722108 |
0.38 |
|
| 2015 |
Sellgren KL, Hawkins BT, Grego S. An optically transparent membrane supports shear stress studies in a three-dimensional microfluidic neurovascular unit model. Biomicrofluidics. 9: 061102. PMID 26594261 DOI: 10.1063/1.4935594 |
0.318 |
|
| 2015 |
Hawkins BT, Grego S, Sellgren KL. Three-dimensional culture conditions differentially affect astrocyte modulation of brain endothelial barrier function in response to transforming growth factor β1. Brain Research. 1608: 167-76. PMID 25721792 DOI: 10.1016/j.brainres.2015.02.025 |
0.41 |
|
| 2015 |
Hawkins BT, Gu YH, Izawa Y, Del Zoppo GJ. Dabigatran abrogates brain endothelial cell permeability in response to thrombin. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 985-92. PMID 25669912 DOI: 10.1038/jcbfm.2015.9 |
0.443 |
|
| 2015 |
Hawkins BT. Hitting a moving target: Therapeutic delivery in the injured brain Advances in Non-Invasive Drug Delivery to the Brain. 22-31. DOI: 10.4155/9781909453937.FSEB2013.13.47 |
0.336 |
|
| 2013 |
del Zoppo GJ, Izawa Y, Hawkins BT. Hemostasis and alterations of the central nervous system. Seminars in Thrombosis and Hemostasis. 39: 856-75. PMID 24166247 DOI: 10.1055/s-0033-1357490 |
0.409 |
|
| 2013 |
Hawkins BT, Gu YH, Izawa Y, Del Zoppo GJ. Disruption of dystroglycan-laminin interactions modulates water uptake by astrocytes. Brain Research. 1503: 89-96. PMID 23395731 DOI: 10.1016/j.brainres.2013.01.049 |
0.411 |
|
| 2012 |
Cannon RE, Peart JC, Hawkins BT, Campos CR, Miller DS. Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain. Proceedings of the National Academy of Sciences of the United States of America. 109: 15930-5. PMID 22949658 DOI: 10.1073/Pnas.1203534109 |
0.774 |
|
| 2012 |
Miller DS, Hawkins BT. Blood-Brain Barrier: Considerations in Drug Development and Delivery Chemical Biology: Approaches to Drug Discovery and Development to Targeting Disease. 133-146. DOI: 10.1002/9781118435762.ch8 |
0.54 |
|
| 2011 |
Osada T, Gu YH, Kanazawa M, Tsubota Y, Hawkins BT, Spatz M, Milner R, del Zoppo GJ. Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1972-85. PMID 21772312 DOI: 10.1038/jcbfm.2011.99 |
0.444 |
|
| 2011 |
Wang X, Hawkins BT, Miller DS. Activating PKC-β1 at the blood-brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1371-5. PMID 21487415 DOI: 10.1038/jcbfm.2011.44 |
0.63 |
|
| 2011 |
Wang X, Hawkins BT, Miller DS. Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 644-52. PMID 21048045 DOI: 10.1096/fj.10-169227 |
0.651 |
|
| 2010 |
Hawkins BT, Rigor RR, Miller DS. Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1593-7. PMID 20628400 DOI: 10.1038/jcbfm.2010.117 |
0.588 |
|
| 2010 |
Rigor RR, Hawkins BT, Miller DS. Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1373-83. PMID 20197783 DOI: 10.1038/jcbfm.2010.21 |
0.645 |
|
| 2010 |
Hawkins BT, Sykes DB, Miller DS. Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1417-25. PMID 20107068 DOI: 10.1523/JNEUROSCI.5103-09.2010 |
0.609 |
|
| 2008 |
Hawkins BT, Egleton RD. Pathophysiology of the blood-brain barrier: animal models and methods. Current Topics in Developmental Biology. 80: 277-309. PMID 17950377 DOI: 10.1016/S0070-2153(07)80007-X |
0.8 |
|
| 2007 |
Hom S, Fleegal MA, Egleton RD, Campos CR, Hawkins BT, Davis TP. Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R1881-92. PMID 17234953 DOI: 10.1152/Ajpregu.00761.2005 |
0.733 |
|
| 2007 |
Hawkins BT, Lundeen TF, Norwood KM, Brooks HL, Egleton RD. Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases. Diabetologia. 50: 202-11. PMID 17143608 DOI: 10.1007/s00125-006-0485-z |
0.77 |
|
| 2007 |
Hawkins BT, Ocheltree SM, Norwood KM, Egleton RD. Decreased blood-brain barrier permeability to fluorescein in streptozotocin-treated rats. Neuroscience Letters. 411: 1-5. PMID 17110033 DOI: 10.1016/j.neulet.2006.09.010 |
0.802 |
|
| 2006 |
Hawkins BT, Egleton RD. Fluorescence imaging of blood-brain barrier disruption. Journal of Neuroscience Methods. 151: 262-7. PMID 16181683 DOI: 10.1016/j.jneumeth.2005.08.006 |
0.785 |
|
| 2005 |
Hawkins BT, Davis TP. The blood-brain barrier/neurovascular unit in health and disease. Pharmacological Reviews. 57: 173-85. PMID 15914466 DOI: 10.1124/pr.57.2.4 |
0.705 |
|
| 2005 |
Brooks TA, Hawkins BT, Huber JD, Egleton RD, Davis TP. Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations. American Journal of Physiology. Heart and Circulatory Physiology. 289: H738-43. PMID 15792985 DOI: 10.1152/Ajpheart.01288.2004 |
0.784 |
|
| 2005 |
Hawkins BT, Egleton RD, Davis TP. Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors. American Journal of Physiology. Heart and Circulatory Physiology. 289: H212-9. PMID 15708958 DOI: 10.1152/ajpheart.01210.2004 |
0.788 |
|
| 2004 |
Hawkins BT, Abbruscato TJ, Egleton RD, Brown RC, Huber JD, Campos CR, Davis TP. Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution. Brain Research. 1027: 48-58. PMID 15494156 DOI: 10.1016/J.Brainres.2004.08.043 |
0.769 |
|
| 2002 |
Abbruscato TJ, Lopez SP, Mark KS, Hawkins BT, Davis TP. Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. Journal of Pharmaceutical Sciences. 91: 2525-38. PMID 12434396 DOI: 10.1002/Jps.10256 |
0.794 |
|
| 2002 |
Hawkins BT, Brown RC, Davis TP. Smoking and ischemic stroke: a role for nicotine? Trends in Pharmacological Sciences. 23: 78-82. PMID 11830264 DOI: 10.1016/S0165-6147(02)01893-X |
0.581 |
|
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