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Jason L. Stein, Ph.D. - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
 2016- Genetics University of North Carolina at Chapel Hill School of Medicine 
Area:
neuroimaging, genetics, neurodevelopment
Website:
steinlab.org
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Year Citation  Score
2023 McAfee JC, Lee S, Lee J, Bell JL, Krupa O, Davis J, Insigne K, Bond ML, Zhao N, Boyle AP, Phanstiel DH, Love MI, Stein JL, Ruzicka WB, Davila-Velderrain J, et al. Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants. Cell Genomics. 3: 100404. PMID 37868037 DOI: 10.1016/j.xgen.2023.100404  0.313
2023 Aygün N, Krupa O, Mory J, Le B, Valone J, Liang D, Love MI, Stein JL. Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis. Biorxiv : the Preprint Server For Biology. PMID 37693528 DOI: 10.1101/2023.08.30.555019  0.384
2023 Jiang Z, Sullivan PF, Li T, Zhao B, Wang X, Luo T, Huang S, Guan PY, Chen J, Yang Y, Stein JL, Li Y, Liu D, Sun L, Zhu H. The pivotal role of the X-chromosome in the genetic architecture of the human brain. Medrxiv : the Preprint Server For Health Sciences. PMID 37693466 DOI: 10.1101/2023.08.30.23294848  0.353
2023 Zhao B, Li T, Fan Z, Yang Y, Shu J, Yang X, Wang X, Luo T, Tang J, Xiong D, Wu Z, Li B, Chen J, Shan Y, Tomlinson C, ... ... Stein JL, et al. Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images. Science (New York, N.Y.). 380: abn6598. PMID 37262162 DOI: 10.1126/science.abn6598  0.375
2023 Aygün N, Liang D, Crouse WL, Keele GR, Love MI, Stein JL. Inferring cell-type-specific causal gene regulatory networks during human neurogenesis. Genome Biology. 24: 130. PMID 37254169 DOI: 10.1186/s13059-023-02959-0  0.302
2023 Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Kim M, Matoba N, Tsai E, Hoh C, Jiao C, Aygun N, Walker RL, Chatzinakos C, ... ... Stein JL, et al. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. Medrxiv : the Preprint Server For Health Sciences. PMID 36945630 DOI: 10.1101/2023.03.03.23286706  0.76
2023 Zhao B, Li Y, Fan Z, Wu Z, Shu J, Yang X, Yang Y, Wang X, Li B, Wang X, Copana C, Yang Y, Lin J, Li Y, Stein JL, et al. Eye-brain connections revealed by multimodal retinal and brain imaging genetics in the UK Biobank. Medrxiv : the Preprint Server For Health Sciences. PMID 36824893 DOI: 10.1101/2023.02.16.23286035  0.377
2023 Matoba N, Le BD, Valone JM, Wolter JM, Mory J, Liang D, Ayg ºn N, Broadaway KA, Bond ML, Mohlke KL, Zylka MJ, Love MI, Stein JL. WNT activity reveals context-specific genetic effects on gene regulation in neural progenitors. Biorxiv : the Preprint Server For Biology. PMID 36798360 DOI: 10.1101/2023.02.07.527357  0.434
2023 Lafferty MJ, Aygün N, Patel NK, Krupa O, Liang D, Wolter JM, Geschwind DH, de la Torre-Ubieta L, Stein JL. MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size. Elife. 12. PMID 36629315 DOI: 10.7554/eLife.79488  0.742
2022 Lemaitre H, Guen YL, Tilot AK, Stein JL, Philippe C, Mangin JF, Fisher SE, Frouin V. Genetic variations within human gained enhancer elements affect human brain sulcal morphology. Neuroimage. 119773. PMID 36442731 DOI: 10.1016/j.neuroimage.2022.119773  0.344
2022 Alagöz G, Molz B, Eising E, Schijven D, Francks C, Stein JL, Fisher SE. Using neuroimaging genomics to investigate the evolution of human brain structure. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200638119. PMID 36161899 DOI: 10.1073/pnas.2200638119  0.418
2022 McAfee JC, Bell JL, Krupa O, Matoba N, Stein JL, Won H. Focus on your locus with a massively parallel reporter assay. Journal of Neurodevelopmental Disorders. 14: 50. PMID 36085003 DOI: 10.1186/s11689-022-09461-x  0.32
2022 Zhao B, Li T, Smith SM, Xiong D, Wang X, Yang Y, Luo T, Zhu Z, Shan Y, Matoba N, Sun Q, Yang Y, Hauberg ME, Bendl J, Fullard JF, ... ... Stein JL, et al. Common variants contribute to intrinsic human brain functional networks. Nature Genetics. 54: 508-517. PMID 35393594 DOI: 10.1038/s41588-022-01039-6  0.418
2022 Brouwer RM, Klein M, Grasby KL, Schnack HG, Jahanshad N, Teeuw J, Thomopoulos SI, Sprooten E, Franz CE, Gogtay N, Kremen WS, Panizzon MS, Olde Loohuis LM, Whelan CD, Aghajani M, ... ... Stein JL, et al. Genetic variants associated with longitudinal changes in brain structure across the lifespan. Nature Neuroscience. PMID 35383335 DOI: 10.1038/s41593-022-01042-4  0.658
2021 Krupa O, Fragola G, Hadden-Ford E, Mory JT, Liu T, Humphrey Z, Rees BW, Krishnamurthy A, Snider WD, Zylka MJ, Wu G, Xing L, Stein JL. NuMorph: Tools for cortical cellular phenotyping in tissue-cleared whole-brain images. Cell Reports. 37: 109802. PMID 34644582 DOI: 10.1016/j.celrep.2021.109802  0.332
2021 Aygün N, Elwell AL, Liang D, Lafferty MJ, Cheek KE, Courtney KP, Mory J, Hadden-Ford E, Krupa O, de la Torre-Ubieta L, Geschwind DH, Love MI, Stein JL. Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis. American Journal of Human Genetics. PMID 34416157 DOI: 10.1016/j.ajhg.2021.07.011  0.803
2021 Zhao B, Li T, Yang Y, Wang X, Luo T, Shan Y, Zhu Z, Xiong D, Hauberg ME, Bendl J, Fullard JF, Roussos P, Li Y, Stein JL, Zhu H. Common genetic variation influencing human white matter microstructure. Science (New York, N.Y.). 372. PMID 34140357 DOI: 10.1126/science.abf3736  0.369
2021 Liang D, Elwell AL, Aygün N, Krupa O, Wolter JM, Kyere FA, Lafferty MJ, Cheek KE, Courtney KP, Yusupova M, Garrett ME, Ashley-Koch A, Crawford GE, Love MI, de la Torre-Ubieta L, ... ... Stein JL, et al. Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. Nature Neuroscience. PMID 34017130 DOI: 10.1038/s41593-021-00858-w  0.791
2020 Medland SE, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Thomopoulos SI, Stein JL, Franke B, Martin NG, Thompson PM. Ten years of enhancing neuro-imaging genetics through meta-analysis: An overview from the ENIGMA Genetics Working Group. Human Brain Mapping. PMID 33300665 DOI: 10.1002/hbm.25311  0.759
2020 Tilot AK, Khramtsova EA, Liang D, Grasby KL, Jahanshad N, Painter J, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Liu S, Brotman SM, Thompson PM, Medland SE, Macciardi F, ... ... Stein JL, et al. The Evolutionary History of Common Genetic Variants Influencing Human Cortical Surface Area. Cerebral Cortex (New York, N.Y. : 1991). PMID 33290510 DOI: 10.1093/cercor/bhaa327  0.752
2020 Matoba N, Love MI, Stein JL. Evaluating brain structure traits as endophenotypes using polygenicity and discoverability. Human Brain Mapping. PMID 33098356 DOI: 10.1002/hbm.25257  0.393
2020 Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, ... ... Stein JL, et al. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications. 11: 4796. PMID 32963231 DOI: 10.1038/s41467-020-18367-y  0.743
2020 Matoba N, Liang D, Sun H, Aygün N, McAfee JC, Davis JE, Raffield LM, Qian H, Piven J, Li Y, Kosuri S, Won H, Stein JL. Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. Translational Psychiatry. 10: 265. PMID 32747698 DOI: 10.1038/S41398-020-00953-9  0.475
2020 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 181: 745. PMID 32359439 DOI: 10.1016/j.cell.2020.04.016  0.817
2020 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 181: 484. PMID 32302575 DOI: 10.1016/j.cell.2020.04.003  0.72
2020 Thompson PM, Jahanshad N, Ching CRK, Salminen LE, Thomopoulos SI, Bright J, Baune BT, Bertolín S, Bralten J, Bruin WB, Bülow R, Chen J, Chye Y, Dannlowski U, de Kovel CGF, ... ... Stein JL, et al. ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries. Translational Psychiatry. 10: 100. PMID 32198361 DOI: 10.1038/S41398-020-0705-1  0.807
2020 Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, ... ... Stein JL, et al. The genetic architecture of the human cerebral cortex. Science (New York, N.Y.). 367. PMID 32193296 DOI: 10.1126/Science.Aay6690  0.806
2019 Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. PMID 31636452 DOI: 10.1038/S41588-019-0511-Y  0.805
2019 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 179: 750-771.e22. PMID 31626773 DOI: 10.1016/J.Cell.2019.09.021  0.847
2019 Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, et al. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. PMID 31303374 DOI: 10.1016/J.Neuron.2019.06.011  0.752
2019 Le BD, Stein JL. Mapping causal pathways from genetics to neuropsychiatric disorders using genome-wide imaging genetics: current status and future directions. Psychiatry and Clinical Neurosciences. PMID 30864184 DOI: 10.1111/Pcn.12839  0.522
2019 Klein M, Walters RK, Demontis D, Stein JL, Hibar DP, Adams HH, Bralten J, Roth Mota N, Schachar R, Sonuga-Barke E, Mattheisen M, Neale BM, Thompson PM, Medland SE, Børglum AD, et al. Genetic Markers of ADHD-Related Variations in Intracranial Volume. The American Journal of Psychiatry. 176: 228-238. PMID 30818988 DOI: 10.1176/Appi.Ajp.2018.18020149  0.663
2019 Liang D, Elwell AL, Krupa O, Cheek KE, Courtney KP, Love MI, de la Torre-Ubieta L, Geschwind DH, Stein JL. 28 GENETIC VARIANTS AFFECTING CHROMATIN ACCESSIBILITY DURING HUMAN NEURONAL DIFFERENTIATION European Neuropsychopharmacology. 29: S74-S75. DOI: 10.1016/J.Euroneuro.2019.07.169  0.346
2019 Krupa O, Liang D, Won H, Love M, Stein J. 27 GENETIC REGULATION OF FOXO3 EXPRESSION INFLUENCES HUMAN NEUROGENESIS AND IS ASSOCIATED WITH CORTICAL SURFACE AREA AND INTELLIGENCE European Neuropsychopharmacology. 29: S74. DOI: 10.1016/J.Euroneuro.2019.07.168  0.37
2019 Klein M, Walters R, Stein J, Adams H, Børglum A, Faraone S, Thompson P, Medland S, Arias-Vásquez A, Franke B. Genetic Factors For Adhd Risk Overlap With Those Influencing Intracranial Volume European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.06.133  0.458
2018 de la Torre-Ubieta L, Stein JL, Won H, Opland CK, Liang D, Lu D, Geschwind DH. The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. Cell. PMID 29307494 DOI: 10.1016/J.Cell.2017.12.014  0.785
2018 Skinner K, Ferris M, Bash R, Shelton A, Smithberger E, Angus S, Golitz B, Sciacky N, Simon J, Stein J, Matsushima G, Ostrom Q, Stetson L, Barnholtz-Sloan J, Dhruv H, et al. TMIC-25. DISSECTING THE ROLE OF HOST GENETICS IN GLIOMA EVOLUTION USING GENETICALLY-ENGINEERED MOUSE MODELS AND THE COLLABORATIVE CROSS Neuro-Oncology. 20: vi261-vi261. DOI: 10.1093/Neuonc/Noy148.1084  0.338
2017 Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624  0.836
2017 Klein M, Stein JL, Børglum A, Faraone SV, Thompson PM, Medland SE, Arias-Vasquez A, Franke B. 100. Investigating the Overlap between Common Genetic Factors for ADHD Risk and Brain Volume Measures Biological Psychiatry. 81: S42. DOI: 10.1016/J.Biopsych.2017.02.112  0.514
2016 Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. PMID 27760116 DOI: 10.1038/Nature19847  0.812
2016 Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/Nn.4398  0.8
2016 Chiocchetti AG, Haslinger D, Stein JL, de la Torre-Ubieta L, Cocchi E, Rothämel T, Lindlar S, Waltes R, Fulda S, Geschwind DH, Freitag CM. Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. Translational Psychiatry. 6: e864. PMID 27483382 DOI: 10.1038/Tp.2016.119  0.41
2016 Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, et al. Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility. Neuron. PMID 27181059 DOI: 10.1016/J.Neuron.2016.04.015  0.535
2016 de la Torre-Ubieta L, Won H, Stein JL, Geschwind DH. Advancing the understanding of autism disease mechanisms through genetics. Nature Medicine. 22: 345-361. PMID 27050589 DOI: 10.1038/Nm.4071  0.769
2016 Becker M, Guadalupe T, Franke B, Hibar DP, Renteria ME, Stein JL, Thompson PM, Francks C, Vernes SC, Fisher SE. Early developmental gene enhancers affect subcortical volumes in the adult human brain. Human Brain Mapping. PMID 26890892 DOI: 10.1002/Hbm.23136  0.765
2016 Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, et al. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nature Neuroscience. PMID 26854805 DOI: 10.1038/Nn.4228  0.722
2016 Thompson PM, Hibar DP, Stein JL, Jahanshad N. Imaging Genomics and ENIGMA Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. 101-115. DOI: 10.1016/B978-0-12-800105-9.00007-X  0.749
2015 Thompson PM, Andreassen OA, Arias-Vasquez A, Bearden CE, Boedhoe PS, Brouwer RM, Buckner RL, Buitelaar JK, Bulaeva KB, Cannon DM, Cohen RA, Conrod PJ, Dale AM, Deary IJ, Dennis EL, ... ... Stein JL, et al. ENIGMA and the Individual: Predicting Factors that Affect the Brain in 35 Countries Worldwide. Neuroimage. PMID 26658930 DOI: 10.1016/J.Neuroimage.2015.11.057  0.84
2015 Berg JM, Lee C, Chen L, Galvan L, Cepeda C, Chen JY, Peñagarikano O, Stein JL, Li A, Oguro-Ando A, Miller JA, Vashisht AA, Starks ME, Kite EP, Tam E, et al. JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron. PMID 26627310 DOI: 10.1016/J.Neuron.2015.10.031  0.61
2015 Martinez RA, Stein JL, Krostag AR, Nelson AM, Marken JS, Menon V, May RC, Yao Z, Kaykas A, Geschwind DH, Grimley JS. Genome engineering of isogenic human ES cells to model autism disorders. Nucleic Acids Research. 43: e65. PMID 25765640 DOI: 10.1093/Nar/Gkv164  0.525
2015 Smith I, Silveirinha V, Stein JL, de la Torre-Ubieta L, Farrimond JA, Williamson EM, Whalley BJ. Human neural stem cell-derived cultures in three-dimensional substrates form spontaneously functional neuronal networks. Journal of Tissue Engineering and Regenerative Medicine. PMID 25712225 DOI: 10.1002/Term.2001  0.703
2015 Stein JL. Copy number variation and brain structure: lessons learned from chromosome 16p11.2. Genome Medicine. 7: 13. PMID 25688292 DOI: 10.1186/S13073-015-0140-8  0.444
2015 Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, et al. Common genetic variants influence human subcortical brain structures. Nature. 520: 224-9. PMID 25607358 DOI: 10.1038/Nature14101  0.817
2015 Hibar DP, Stein JL, Jahanshad N, Kohannim O, Hua X, Toga AW, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Weiner MW, Thompson PM. Genome-wide interaction analysis reveals replicated epistatic effects on brain structure. Neurobiology of Aging. 36: S151-8. PMID 25264344 DOI: 10.1016/J.Neurobiolaging.2014.02.033  0.831
2014 Ashbrook DG, Williams RW, Lu L, Stein JL, Hibar DP, Nichols TE, Medland SE, Thompson PM, Hager R. Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. Bmc Genomics. 15: 850. PMID 25280473 DOI: 10.1186/1471-2164-15-850  0.76
2014 Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 83: 69-86. PMID 24991955 DOI: 10.1016/J.Neuron.2014.05.035  0.79
2014 Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 8: 153-82. PMID 24399358 DOI: 10.1007/S11682-013-9269-5  0.788
2014 Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, ... ... Stein JL, et al. Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Molecular Psychiatry. 19: 452-61. PMID 23568192 DOI: 10.1038/Mp.2013.37  0.744
2013 Colom R, Stein JL, Rajagopalan P, Martínez K, Hermel D, Wang Y, Álvarez-Linera J, Burgaleta M, Quiroga MÁ, Shih PC, Thompson PM. Hippocampal structure and human cognition: key role of spatial processing and evidence supporting the efficiency hypothesis in females. Intelligence. 41: 129-140. PMID 25632167 DOI: 10.1016/J.Intell.2013.01.002  0.384
2013 Hibar DP, Medland SE, Stein JL, Kim S, Shen L, Saykin AJ, de Zubicaray GI, McMahon KL, Montgomery GW, Martin NG, Wright MJ, Djurovic S, Agartz IA, Andreassen OA, Thompson PM. Genetic clustering on the hippocampal surface for genome-wide association studies. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 16: 690-7. PMID 24579201 DOI: 10.1007/978-3-642-40763-5_85  0.685
2013 Hibar DP, Stein JL, Jahanshad N, Kohannim O, Toga AW, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Weiner MW, Thompson PM. Exhaustive search of the SNP-sNP interactome identifies epistatic effects on brain volume in two cohorts. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 16: 600-7. PMID 24505811 DOI: 10.1007/978-3-642-40760-4_75  0.815
2013 Stein JL, Parikshak NN, Geschwind DH. Rare inherited variation in autism: beginning to see the forest and a few trees. Neuron. 77: 209-11. PMID 23352155 DOI: 10.1016/J.Neuron.2013.01.010  0.716
2013 Hibar DP, Stein JL, Ryles AB, Kohannim O, Jahanshad N, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Saykin AJ, Jack CR, Weiner MW, et al. Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects. Brain Imaging and Behavior. 7: 102-15. PMID 22903471 DOI: 10.1007/S11682-012-9199-7  0.839
2013 Rosenblatt JD, Stein JL, Bogomolov M, Thompson P, Benjamini Y. vGWAS revisited: a novel and powerful approach to voxelwise genome-wide association studies F1000research. 4. DOI: 10.7490/F1000Research.1093627.1  0.429
2012 Rajagopalan P, Jahanshad N, Stein JL, Hua X, Madsen SK, Kohannim O, Hibar DP, Toga AW, Jack CR, Saykin AJ, Green RC, Weiner MW, Bis JC, Kuller LH, Riverol M, et al. Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment. Neuroimage. Clinical. 1: 179-87. PMID 24179750 DOI: 10.1016/J.Nicl.2012.09.012  0.831
2012 Kohannim O, Hibar DP, Jahanshad N, Stein JL, Hua X, Toga AW, Jack CR, Weiner MW, Thompson PM. PREDICTING TEMPORAL LOBE VOLUME ON MRI FROM GENOTYPES USING L(1)-L(2) REGULARIZED REGRESSION. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 1160-1163. PMID 22903144 DOI: 10.1109/ISBI.2012.6235766  0.798
2012 Kohannim O, Hibar DP, Stein JL, Jahanshad N, Hua X, Rajagopalan P, Toga AW, Jack CR, Weiner MW, de Zubicaray GI, McMahon KL, Hansell NK, Martin NG, Wright MJ, Thompson PM, et al. Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression. Frontiers in Neuroscience. 6: 115. PMID 22888310 DOI: 10.3389/Fnins.2012.00115  0.835
2012 Novak NM, Stein JL, Medland SE, Hibar DP, Thompson PM, Toga AW. EnigmaVis: online interactive visualization of genome-wide association studies of the Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 15: 414-8. PMID 22856375 DOI: 10.1017/Thg.2012.17  0.765
2012 Hibar DP, Jahanshad N, Stein JL, Kohannim O, Toga AW, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Thompson PM. Alzheimer's disease risk gene, GAB2, is associated with regional brain volume differences in 755 young healthy twins. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 15: 286-95. PMID 22856364 DOI: 10.1017/Thg.2012.15  0.838
2012 Smit DJ, van 't Ent D, de Zubicaray G, Stein JL. Neuroimaging and genetics: exploring, searching, and finding. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 15: 267-72. PMID 22856362 DOI: 10.1017/Thg.2012.20  0.524
2012 Lutkenhoff E, Karlsgodt KH, Gutman B, Stein JL, Thompson PM, Cannon TD, Jentsch JD. Structural and functional neuroimaging phenotypes in dysbindin mutant mice. Neuroimage. 62: 120-9. PMID 22584233 DOI: 10.1016/J.Neuroimage.2012.05.008  0.708
2012 Braskie MN, Jahanshad N, Stein JL, Barysheva M, Johnson K, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Ringman JM, Toga AW, Thompson PM. Relationship of a variant in the NTRK1 gene to white matter microstructure in young adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5964-72. PMID 22539856 DOI: 10.1523/Jneurosci.5561-11.2012  0.761
2012 Kohannim O, Jahanshad N, Braskie MN, Stein JL, Chiang MC, Reese AH, Hibar DP, Toga AW, McMahon KL, de Zubicaray GI, Medland SE, Montgomery GW, Martin NG, Wright MJ, Thompson PM. Predicting white matter integrity from multiple common genetic variants. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2012-9. PMID 22510721 DOI: 10.1038/Npp.2012.49  0.821
2012 Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, ... ... Stein JL, et al. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nature Genetics. 44: 545-51. PMID 22504421 DOI: 10.1038/Ng.2237  0.666
2012 Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics. 44: 552-61. PMID 22504417 DOI: 10.1038/Ng.2250  0.808
2012 Sanders SJ, Murtha MT, Gupta AR, Murdoch JD, Raubeson MJ, Willsey AJ, Ercan-Sencicek AG, DiLullo NM, Parikshak NN, Stein JL, Walker MF, Ober GT, Teran NA, Song Y, El-Fishawy P, et al. De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature. 485: 237-41. PMID 22495306 DOI: 10.1038/Nature10945  0.734
2012 Jahanshad N, Kohannim O, Hibar DP, Stein JL, McMahon KL, de Zubicaray GI, Medland SE, Montgomery GW, Whitfield JB, Martin NG, Wright MJ, Toga AW, Thompson PM. Brain structure in healthy adults is related to serum transferrin and the H63D polymorphism in the HFE gene. Proceedings of the National Academy of Sciences of the United States of America. 109: E851-9. PMID 22232660 DOI: 10.1073/Pnas.1105543109  0.824
2012 Vounou M, Janousova E, Wolz R, Stein JL, Thompson PM, Rueckert D, Montana G. Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease. Neuroimage. 60: 700-16. PMID 22209813 DOI: 10.1016/J.Neuroimage.2011.12.029  0.577
2011 Hibar DP, Kohannim O, Stein JL, Chiang MC, Thompson PM. Multilocus genetic analysis of brain images. Frontiers in Genetics. 2: 73. PMID 22303368 DOI: 10.3389/Fgene.2011.00073  0.841
2011 Kochunov P, Glahn DC, Nichols TE, Winkler AM, Hong EL, Holcomb HH, Stein JL, Thompson PM, Curran JE, Carless MA, Olvera RL, Johnson MP, Cole SA, Kochunov V, Kent J, et al. Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain. Frontiers in Neuroscience. 5: 120. PMID 22028680 DOI: 10.3389/Fnins.2011.00120  0.559
2011 Braskie MN, Jahanshad N, Stein JL, Barysheva M, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Ringman JM, Toga AW, Thompson PM. Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6764-70. PMID 21543606 DOI: 10.1523/Jneurosci.5794-10.2011  0.809
2011 Ho AJ, Raji CA, Saharan P, DeGiorgio A, Madsen SK, Hibar DP, Stein JL, Becker JT, Lopez OL, Toga AW, Thompson PM. Hippocampal volume is related to body mass index in Alzheimer's disease. Neuroreport. 22: 10-4. PMID 21539003 DOI: 10.1097/Wnr.0B013E3283412868  0.795
2011 Stein JL, Hibar DP, Madsen SK, Khamis M, McMahon KL, de Zubicaray GI, Hansell NK, Montgomery GW, Martin NG, Wright MJ, Saykin AJ, Jack CR, Weiner MW, Toga AW, Thompson PM, et al. Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. Molecular Psychiatry. 16: 927-37, 881. PMID 21502949 DOI: 10.1038/Mp.2011.32  0.776
2011 Hibar DP, Stein JL, Kohannim O, Jahanshad N, Saykin AJ, Shen L, Kim S, Pankratz N, Foroud T, Huentelman MJ, Potkin SG, Jack CR, Weiner MW, Toga AW, Thompson PM, et al. Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects. Neuroimage. 56: 1875-91. PMID 21497199 DOI: 10.1016/J.Neuroimage.2011.03.077  0.847
2011 Joshi AA, Leporé N, Joshi SH, Lee AD, Barysheva M, Stein JL, McMahon KL, Johnson K, de Zubicaray GI, Martin NG, Wright MJ, Toga AW, Thompson PM. The contribution of genes to cortical thickness and volume. Neuroreport. 22: 101-5. PMID 21233781 DOI: 10.1097/Wnr.0B013E3283424C84  0.608
2011 Ho AJ, Raji CA, Becker JT, Lopez OL, Kuller LH, Hua X, Dinov ID, Stein JL, Rosano C, Toga AW, Thompson PM. The effects of physical activity, education, and body mass index on the aging brain. Human Brain Mapping. 32: 1371-82. PMID 20715081 DOI: 10.1002/Hbm.21113  0.792
2011 Kohannim O, Hibar DP, Stein JL, Jahanshad N, Jack CR, Weiner MW, Toga AW, Thompson PM. Boosting power to detect genetic associations in imaging using multi-locus, genome-wide scans and ridge regression Proceedings - International Symposium On Biomedical Imaging. 1855-1859. DOI: 10.1109/ISBI.2011.5872769  0.801
2011 Hibar DP, Stein JL, Kohannim O, Jahanshad N, Jack CR, Weiner MW, Toga AW, Thompson PM. Principal components regression: Multivariate, gene-based tests in imaging genomics Proceedings - International Symposium On Biomedical Imaging. 289-293. DOI: 10.1109/ISBI.2011.5872408  0.785
2011 Stein JL, Hibar DP, Madsen SK, Khamis M, McMahon KL, Zubicaray GID, Hansell NK, Montgomery GW, Martin NG, Wright MJ, Saykin AJ, Jack CRJ, Weiner MW, Toga AW, Thompson PM. Genome-wide association reveals dopamine-related genetic effects on caudate volume Molecular Psychiatry. 16: 881-881. DOI: 10.1038/Mp.2011.98  0.527
2010 Ho AJ, Raji CA, Becker JT, Lopez OL, Kuller LH, Hua X, Lee S, Hibar D, Dinov ID, Stein JL, Jack CR, Weiner MW, Toga AW, Thompson PM, et al. Obesity is linked with lower brain volume in 700 AD and MCI patients. Neurobiology of Aging. 31: 1326-39. PMID 20570405 DOI: 10.1016/J.Neurobiolaging.2010.04.006  0.799
2010 Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, et al. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 265-73. PMID 20451875 DOI: 10.1016/J.Jalz.2010.03.013  0.534
2010 Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, et al. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proceedings of the National Academy of Sciences of the United States of America. 107: 8404-9. PMID 20404173 DOI: 10.1073/Pnas.0910878107  0.822
2010 Stein JL, Hua X, Morra JH, Lee S, Hibar DP, Ho AJ, Leow AD, Toga AW, Sul JH, Kang HM, Eskin E, Saykin AJ, Shen L, Foroud T, Pankratz N, et al. Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage. 51: 542-54. PMID 20197096 DOI: 10.1016/J.Neuroimage.2010.02.068  0.823
2010 Stein JL, Hua X, Lee S, Ho AJ, Leow AD, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, et al. Voxelwise genome-wide association study (vGWAS). Neuroimage. 53: 1160-74. PMID 20171287 DOI: 10.1016/J.Neuroimage.2010.02.032  0.847
2010 Ho AJ, Hua X, Lee S, Leow AD, Yanovsky I, Gutman B, Dinov ID, Leporé N, Stein JL, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, et al. Comparing 3 T and 1.5 T MRI for tracking Alzheimer's disease progression with tensor-based morphometry. Human Brain Mapping. 31: 499-514. PMID 19780044 DOI: 10.1002/Hbm.20882  0.782
2009 Eckstein I, Shattuck DW, Stein JL, McMahon KL, de Zubicaray G, Wright MJ, Thompson PM, Toga AW. Active fibers: matching deformable tract templates to diffusion tensor images. Neuroimage. 47: T82-9. PMID 19457360 DOI: 10.1016/J.Neuroimage.2009.01.065  0.491
2009 Stein J, DeGiorgio A, Madsen S, Avedissian C, Chou Y, Morra J, Toga A, McMahon K, de Zubicaray G, Wright M, Thompson P. Genetic Influences on Hippocampal Structure Mapped in 288 Twins Neuroimage. 47: S140. DOI: 10.1016/S1053-8119(09)71388-6  0.723
2009 Braber Ad, Ent Dv', Cath D, Boomsma D, Barysheva M, Lee A, Foland-Ross L, Stein J, Thompson P, Geus Ed. A DTI Study of Monozygotic Twins Discordant for Obsessive-Compulsive Symptoms Neuroimage. 47. DOI: 10.1016/S1053-8119(09)71227-3  0.642
2007 Stein JL, Wiedholz LM, Bassett DS, Weinberger DR, Zink CF, Mattay VS, Meyer-Lindenberg A. A validated network of effective amygdala connectivity. Neuroimage. 36: 736-45. PMID 17475514 DOI: 10.1016/J.Neuroimage.2007.03.022  0.331
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