Carl Ernst - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Neurogenesis

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, ... ... Ernst C, et al. Correction: A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30643220 DOI: 10.1038/s41436-018-0413-x  0.64
2018 Wardeh A, Jackson T, Nelson B, Ernst C, Théroux JF, Al-Hertani W, Sobering AK, Maj MC. Identification of a de novo case of -related Ehlers-Danlos syndrome in an infant in the West Indies leading to improved targeted clinical care. Clinical Case Reports. 6: 2256-2261. PMID 30455932 DOI: 10.1002/ccr3.1873  0.56
2018 Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, Megat S, Ceredig RA, Ernst C, Turecki G, Chavant V, Theroux JF, Lacaud A, Joganah LE, Lelievre V, et al. A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30249798 DOI: 10.1523/JNEUROSCI.1004-18.2018  1
2018 Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, ... ... Ernst C, et al. A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30245510 DOI: 10.1038/s41436-018-0290-3  0.64
2018 Bell S, Maussion G, Jefri M, Peng H, Theroux JF, Silveira H, Soubannier V, Wu H, Hu P, Galat E, Torres-Platas SG, Boudreau-Pinsonneault C, O'Leary LA, Galat V, Turecki G, ... ... Ernst C, et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons. Stem Cell Reports. PMID 29937144 DOI: 10.1016/j.stemcr.2018.05.018  1
2017 Lutz PE, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D, Chay MA, Yang J, Larivière V, M'Boutchou MN, van Kempen LC, ... ... Ernst C, et al. Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence. The American Journal of Psychiatry. appiajp201716111286. PMID 28750583 DOI: 10.1176/appi.ajp.2017.16111286  1
2017 Vaillancourt K, Ernst C, Mash D, Turecki G. DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects. Genes. 8. PMID 28498318 DOI: 10.3390/genes8050138  1
2017 Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O'Dushlaine C, ... ... Ernst C, et al. Cover Image, Volume 173A, Number 2, February 2017. American Journal of Medical Genetics. Part A. 173: i. PMID 28102589 DOI: 10.1002/ajmg.a.37896  1
2017 Chen GG, Gross JA, Lutz PE, Vaillancourt K, Maussion G, Bramoulle A, Théroux JF, Gardini ES, Ehlert U, Bourret G, Masurel A, Lepage P, Mechawar N, Turecki G, Ernst C. Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine. Bmc Genomics. 18: 96. PMID 28100169 DOI: 10.1186/s12864-017-3489-9  1
2016 Bell S, Peng H, Crapper L, Kolobova I, Maussion G, Vasuta C, Yerko V, Wong TP, Ernst C. A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing. Stem Cells Translational Medicine. PMID 28170165 DOI: 10.1002/sctm.16-0158  0.8
2016 Bell S, Kolobova I, Crapper L, Ernst C. Lesch-Nyhan Syndrome: Models, Theories, and Therapies. Molecular Syndromology. 7: 302-311. PMID 27920633 DOI: 10.1159/000449296  0.8
2016 Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O'Dushlaine C, ... ... Ernst C, et al. Implication of LRRC4C and DPP6 in neurodevelopmental disorders. American Journal of Medical Genetics. Part A. PMID 27759917 DOI: 10.1002/ajmg.a.38021  1
2016 Farmer WT, Abrahamsson T, Chierzi S, Lui C, Zaelzer C, Jones EV, Bally BP, Chen GG, Théroux JF, Peng J, Bourque CW, Charron F, Ernst C, Sjöström PJ, Murai KK. Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling. Science (New York, N.Y.). 351: 849-54. PMID 26912893 DOI: 10.1126/science.aab3103  1
2016 Merner N, Forgeot d'Arc B, Bell SC, Maussion G, Peng H, Gauthier J, Crapper L, Hamdan FF, Michaud JL, Mottron L, Rouleau GA, Ernst C. A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review. American Journal of Medical Genetics. Part A. PMID 26789910 DOI: 10.1002/ajmg.a.37566  1
2015 Gross JA, Pacis A, Chen GG, Barreiro LB, Ernst C, Turecki G. Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution. Bmc Genomics. 16: 672. PMID 26334641 DOI: 10.1186/s12864-015-1875-8  1
2015 Maussion G, Diallo AB, Gigek CO, Chen ES, Crapper L, Théroux JF, Chen GG, Vasuta C, Ernst C. Investigation of genes important in neurodevelopment disorders in adult human brain. Human Genetics. PMID 26194112 DOI: 10.1007/s00439-015-1584-z  1
2015 Lopez JP, Diallo A, Cruceanu C, Fiori LM, Laboissiere S, Guillet I, Fontaine J, Ragoussis J, Benes V, Turecki G, Ernst C. Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing. Bmc Medical Genomics. 8: 35. PMID 26130076 DOI: 10.1186/s12920-015-0109-x  1
2015 Crapper L, Ernst C. Comparative analysis of self-injury in people with psychopathology or neurodevelopmental disorders. Pediatric Clinics of North America. 62: 619-31. PMID 26022166 DOI: 10.1016/j.pcl.2015.03.001  1
2015 Gigek CO, Chen ES, Ota VK, Maussion G, Peng H, Vaillancourt K, Diallo AB, Lopez JP, Crapper L, Vasuta C, Chen GG, Ernst C. A molecular model for neurodevelopmental disorders. Translational Psychiatry. 5: e565. PMID 25966365 DOI: 10.1038/tp.2015.56  0.8
2015 Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G. Astrocytic abnormalities and global DNA methylation patterns in depression and suicide. Molecular Psychiatry. 20: 320-8. PMID 24662927 DOI: 10.1038/mp.2014.21  1
2015 Lopez JP, Diallo A, Cruceanu C, Fiori LM, Laboissiere S, Guillet I, Fontaine J, Ragoussis J, Benes V, Turecki G, Ernst C. Biomarker discovery: Quantification of microRNAs and other small non-coding RNAs using next generation sequencing Bmc Medical Genomics. 8. DOI: 10.1186/s12920-015-0109-x  1
2014 Nieboer H, De Brucker Y, Ernst C, Van Den Berghe Ch, De Maeseneer M. Traumatic avulsion of the trochanter minor in a 15-year-old boy: an uncommon injury. Jbr-Btr : Organe De La SociéTé Royale Belge De Radiologie (Srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (Kbvr). 97: 373. PMID 25786301  0.01
2014 Chen ES, Gigek CO, Rosenfeld JA, Diallo AB, Maussion G, Chen GG, Vaillancourt K, Lopez JP, Crapper L, Poujol R, Shaffer LG, Bourque G, Ernst C. Molecular convergence of neurodevelopmental disorders. American Journal of Human Genetics. 95: 490-508. PMID 25307298 DOI: 10.1016/j.ajhg.2014.09.013  1
2014 Blumenthal I, Ragavendran A, Erdin S, Klei L, Sugathan A, Guide JR, Manavalan P, Zhou JQ, Wheeler VC, Levin JZ, Ernst C, Roeder K, Devlin B, Gusella JF, Talkowski ME. Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families. American Journal of Human Genetics. 94: 870-83. PMID 24906019 DOI: 10.1016/j.ajhg.2014.05.004  1
2014 Chen GG, Diallo AB, Poujol R, Nagy C, Staffa A, Vaillancourt K, Lutz PE, Ota VK, Mash DC, Turecki G, Ernst C. BisQC: an operational pipeline for multiplexed bisulfite sequencing. Bmc Genomics. 15: 290. PMID 24734894 DOI: 10.1186/1471-2164-15-290  1
2013 Ernst C, Morton CC. Identification and function of long non-coding RNA. Frontiers in Cellular Neuroscience. 7: 168. PMID 24106460 DOI: 10.3389/fncel.2013.00168  1
2013 Lindgren AM, Hoyos T, Talkowski ME, Hanscom C, Blumenthal I, Chiang C, Ernst C, Pereira S, Ordulu Z, Clericuzio C, Drautz JM, Rosenfeld JA, Shaffer LG, Velsher L, Pynn T, et al. Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate. Human Genetics. 132: 537-52. PMID 23354975 DOI: 10.1007/s00439-013-1263-x  1
2013 Ruderfer DM, Chambert K, Moran J, Talkowski M, Chen ES, Gigek C, Gusella JF, Blackwood DH, Corvin A, Gurling HM, Hultman CM, Kirov G, Magnusson P, O'Donovan MC, Owen MJ, ... ... Ernst C, et al. Mosaic copy number variation in schizophrenia. European Journal of Human Genetics : Ejhg. 21: 1007-11. PMID 23321615 DOI: 10.1038/ejhg.2012.287  1
2013 Lopez JP, Mamdani F, Labonte B, Beaulieu MM, Yang JP, Berlim MT, Ernst C, Turecki G. Epigenetic regulation of BDNF expression according to antidepressant response. Molecular Psychiatry. 18: 398-9. PMID 22547115 DOI: 10.1038/mp.2012.38  1
2012 Talkowski ME, Maussion G, Crapper L, Rosenfeld JA, Blumenthal I, Hanscom C, Chiang C, Lindgren A, Pereira S, Ruderfer D, Diallo AB, Lopez JP, Turecki G, Chen ES, Gigek C, ... ... Ernst C, et al. Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities. American Journal of Human Genetics. 91: 1128-34. PMID 23217328 DOI: 10.1016/j.ajhg.2012.10.016  1
2012 Perlis RH, Ruderfer D, Maussion G, Chambert K, Gallagher P, Turecki G, Ernst C. Bipolar disorder and a history of suicide attempts with a duplication in 5HTR1A. The American Journal of Psychiatry. 169: 1213-4. PMID 23128927 DOI: 10.1176/appi.ajp.2012.12050592  1
2012 Ernst C, Marshall CR, Shen Y, Metcalfe K, Rosenfeld J, Hodge JC, Torres A, Blumenthal I, Chiang C, Pillalamarri V, Crapper L, Diallo AB, Ruderfer D, Pereira S, Sklar P, et al. Highly penetrant alterations of a critical region including BDNF in human psychopathology and obesity. Archives of General Psychiatry. 69: 1238-46. PMID 23044507 DOI: 10.1001/archgenpsychiatry.2012.660  1
2012 Perlis RH, Ruderfer D, Hamilton SP, Ernst C. Copy number variation in subjects with major depressive disorder who attempted suicide. Plos One. 7: e46315. PMID 23029476 DOI: 10.1371/journal.pone.0046315  1
2012 Maussion G, Yang J, Yerko V, Barker P, Mechawar N, Ernst C, Turecki G. Regulation of a truncated form of tropomyosin-related kinase B (TrkB) by Hsa-miR-185* in frontal cortex of suicide completers. Plos One. 7: e39301. PMID 22802923 DOI: 10.1371/journal.pone.0039301  1
2012 Talkowski ME, Rosenfeld JA, Blumenthal I, Pillalamarri V, Chiang C, Heilbut A, Ernst C, Hanscom C, Rossin E, Lindgren AM, Pereira S, Ruderfer D, Kirby A, Ripke S, Harris DJ, et al. Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries. Cell. 149: 525-37. PMID 22521361 DOI: 10.1016/j.cell.2012.03.028  1
2012 Chiang C, Jacobsen JC, Ernst C, Hanscom C, Heilbut A, Blumenthal I, Mills RE, Kirby A, Lindgren AM, Rudiger SR, McLaughlan CJ, Bawden CS, Reid SJ, Faull RL, Snell RG, et al. Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration. Nature Genetics. 44: 390-7, S1. PMID 22388000 DOI: 10.1038/ng.2202  1
2012 Turecki G, Ernst C, Jollant F, Labonté B, Mechawar N. The neurodevelopmental origins of suicidal behavior. Trends in Neurosciences. 35: 14-23. PMID 22177979 DOI: 10.1016/j.tins.2011.11.008  1
2012 Ernst C, Brezo J, Klempan T, Lalovic A, Turecki G. Biological markers of suicidal behaviour Suicide From a Global Perspective: Psychiatric Approaches. 89-95.  1
2011 Talkowski ME, Mullegama SV, Rosenfeld JA, van Bon BW, Shen Y, Repnikova EA, Gastier-Foster J, Thrush DL, Kathiresan S, Ruderfer DM, Chiang C, Hanscom C, Ernst C, Lindgren AM, Morton CC, et al. Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder. American Journal of Human Genetics. 89: 551-63. PMID 21981781 DOI: 10.1016/j.ajhg.2011.09.011  1
2011 Ernst CW, Van Der Werff Ten Bosch J, Desprechins B, de Mey J, De Maeseneer M. Malignant transformation of an abdominal inflammatory myofibroblastic tumor with distant metastases in a child. Jbr-Btr : Organe De La SociéTé Royale Belge De Radiologie (Srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (Kbvr). 94: 78-80. PMID 21699040  0.76
2011 Ernst C, Nagy C, Kim S, Yang JP, Deng X, Hellstrom IC, Choi KH, Gershenfeld H, Meaney MJ, Turecki G. Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completers. Biological Psychiatry. 70: 312-9. PMID 21571253 DOI: 10.1016/j.biopsych.2011.03.038  1
2011 Talkowski ME, Ernst C, Heilbut A, Chiang C, Hanscom C, Lindgren A, Kirby A, Liu S, Muddukrishna B, Ohsumi TK, Shen Y, Borowsky M, Daly MJ, Morton CC, Gusella JF. Next-generation sequencing strategies enable routine detection of balanced chromosome rearrangements for clinical diagnostics and genetic research. American Journal of Human Genetics. 88: 469-81. PMID 21473983 DOI: 10.1016/j.ajhg.2011.03.013  1
2011 Chen ES, Ernst C, Turecki G. The epigenetic effects of antidepressant treatment on human prefrontal cortex BDNF expression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 427-9. PMID 21134314 DOI: 10.1017/S1461145710001422  1
2011 Ernst C, Wanner B, Brezo J, Vitaro F, Tremblay R, Turecki G. A deletion in tropomyosin-related kinase B and the development of human anxiety. Biological Psychiatry. 69: 604-7. PMID 21126736 DOI: 10.1016/j.biopsych.2010.10.008  1
2010 Ernst C, Morton CC, Gusella JF. Self-injurious behaviours in people with and without intellectual delay: implications for the genetics of suicide. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 527-8. PMID 19887018 DOI: 10.1017/S1461145709990885  1
2009 Ernst C, Mechawar N, Turecki G. Suicide neurobiology. Progress in Neurobiology. 89: 315-33. PMID 19766697 DOI: 10.1016/j.pneurobio.2009.09.001  1
2009 Ernst C, Chen ES, Turecki G. Histone methylation and decreased expression of TrkB.T1 in orbital frontal cortex of suicide completers. Molecular Psychiatry. 14: 830-2. PMID 19696771 DOI: 10.1038/mp.2009.35  1
2009 Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. Plos One. 4: e6585. PMID 19668376 DOI: 10.1371/journal.pone.0006585  1
2009 Klempan TA, Ernst C, Deleva V, Labonte B, Turecki G. Characterization of QKI gene expression, genetics, and epigenetics in suicide victims with major depressive disorder. Biological Psychiatry. 66: 824-31. PMID 19545858 DOI: 10.1016/j.biopsych.2009.05.010  1
2009 Ernst C, Dumoulin P, Cabot S, Erickson J, Turecki G. SNAT1 and a family with high rates of suicidal behavior. Neuroscience. 162: 415-22. PMID 19442705 DOI: 10.1016/j.neuroscience.2009.05.010  1
2009 Ernst C, Deleva V, Deng X, Sequeira A, Pomarenski A, Klempan T, Ernst N, Quirion R, Gratton A, Szyf M, Turecki G. Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Archives of General Psychiatry. 66: 22-32. PMID 19124685 DOI: 10.1001/archpsyc.66.1.22  1
2009 Klempan TA, Sequeira A, Canetti L, Lalovic A, Ernst C, ffrench-Mullen J, Turecki G. Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression. Molecular Psychiatry. 14: 175-89. PMID 17938633 DOI: 10.1038/sj.mp.4002110  1
2008 Ernst C, McGowan PO, Deleva V, Meaney MJ, Szyf M, Turecki G. The effects of pH on DNA methylation state: In vitro and post-mortem brain studies. Journal of Neuroscience Methods. 174: 123-5. PMID 18656499 DOI: 10.1016/j.jneumeth.2008.06.027  1
2008 McGowan PO, Sasaki A, Huang TC, Unterberger A, Suderman M, Ernst C, Meaney MJ, Turecki G, Szyf M. Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. Plos One. 3: e2085. PMID 18461137 DOI: 10.1371/journal.pone.0002085  1
2008 Ernst C, Bureau A, Turecki G. Application of microarray outlier detection methodology to psychiatric research. Bmc Psychiatry. 8: 29. PMID 18433482 DOI: 10.1186/1471-244X-8-29  1
2007 Ernst C, Sequeira A, Klempan T, Ernst N, Ffrench-Mullen J, Turecki G. Confirmation of region-specific patterns of gene expression in the human brain. Neurogenetics. 8: 219-24. PMID 17375343 DOI: 10.1007/s10048-007-0084-2  1
2006 Ernst C, Olson AK, Pinel JP, Lam RW, Christie BR. Antidepressant effects of exercise: evidence for an adult-neurogenesis hypothesis? Journal of Psychiatry & Neuroscience : Jpn. 31: 84-92. PMID 16575423  1
2006 Olson AK, Eadie BD, Ernst C, Christie BR. Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways. Hippocampus. 16: 250-60. PMID 16411242 DOI: 10.1002/hipo.20157  1
2006 Ernst C, Christie BR. The putative neural stem cell marker, nestin, is expressed in heterogeneous cell types in the adult rat neocortex. Neuroscience. 138: 183-8. PMID 16343784 DOI: 10.1016/j.neuroscience.2005.10.065  1
2006 Ernst C, Christie BR. Temporally specific proliferation events are induced in the hippocampus following acute focal injury. Journal of Neuroscience Research. 83: 349-61. PMID 16342206 DOI: 10.1002/jnr.20724  1
2006 Christie BR, Li AM, Redila VA, Booth H, Wong BK, Eadie BD, Ernst C, Simpson EM. Deletion of the nuclear receptor Nr2e1 impairs synaptic plasticity and dendritic structure in the mouse dentate gyrus. Neuroscience. 137: 1031-7. PMID 16289828 DOI: 10.1016/j.neuroscience.2005.08.091  1
2006 Ernst C, Christie BR. Isolectin-IB 4 as a vascular stain for the study of adult neurogenesis. Journal of Neuroscience Methods. 150: 138-42. PMID 16095716 DOI: 10.1016/j.jneumeth.2005.06.018  1
2005 Ernst C, Christie BR. Nestin-expressing cells and their relationship to mitotically active cells in the subventricular zones of the adult rat. The European Journal of Neuroscience. 22: 3059-66. PMID 16367772 DOI: 10.1111/j.1460-9568.2005.04499.x  1
2004 Ernst C, Lalovic A, Lesage A, Seguin M, Tousignant M, Turecki G. Suicide and no axis I psychopathology. Bmc Psychiatry. 4: 7. PMID 15053834 DOI: 10.1186/1471-244X-4-7  1
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