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Jeffrey M. Harder, Ph.D. - Publications

Affiliations: 
School of Medicine and Dentistry University of Rochester, Rochester, NY 
Area:
Retina, glaucoma
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tribble JR, Harder JM, Williams PA, John SWM. Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice. Molecular Brain. 13: 81. PMID 32450896 DOI: 10.1186/S13041-020-00603-7  0.401
2019 Williams PA, Braine CE, Kizhatil K, Foxworth NE, Tolman NG, Harder JM, Scott RA, Sousa GL, Panitch A, Howell GR, John SWM. Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma. Molecular Neurodegeneration. 14: 6. PMID 30670050 DOI: 10.1186/S13024-018-0303-3  0.558
2018 Harder JM, Williams PA, Soto I, Foxworth NE, Fernandes KA, Freeburg NF, Libby RT, John SWM. Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice. Cell Death & Disease. 9: 705. PMID 29899326 DOI: 10.1038/S41419-018-0705-8  0.693
2018 Williams PA, Harder JM, Cardozo BH, Foxworth NE, John SWM. Nicotinamide treatment robustly protects from inherited mouse glaucoma. Communicative & Integrative Biology. 11: e1356956. PMID 29497468 DOI: 10.1080/19420889.2017.1356956  0.512
2017 Williams PA, Harder JM, John SWM. Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma. Journal of Glaucoma. PMID 28858158 DOI: 10.1097/Ijg.0000000000000767  0.411
2017 Williams PA, Harder JM, Foxworth NE, Cardozo BH, Cochran KE, John SWM. Nicotinamide and WLD(S) Act Together to Prevent Neurodegeneration in Glaucoma. Frontiers in Neuroscience. 11: 232. PMID 28487632 DOI: 10.3389/Fnins.2017.00232  0.509
2017 Harder JM, Braine CE, Williams PA, Zhu X, MacNicoll KH, Sousa GL, Buchanan RA, Smith RS, Libby RT, Howell GR, John SWM. Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective. Proceedings of the National Academy of Sciences of the United States of America. PMID 28446616 DOI: 10.1073/Pnas.1608769114  0.629
2017 Williams PA, Harder JM, Foxworth NE, Cochran KE, Philip VM, Porciatti V, Smithies O, John SW. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science (New York, N.Y.). 355: 756-760. PMID 28209901 DOI: 10.1126/Science.Aal0092  0.395
2016 Graham LC, Harder JM, Soto I, de Vries WN, John SW, Howell GR. Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease. Scientific Reports. 6: 21568. PMID 26888450 DOI: 10.1038/Srep21568  0.31
2015 Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT. Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities. Experimental Eye Research. PMID 26116903 DOI: 10.1016/J.Exer.2015.06.019  0.608
2014 John SW, Harder JM, Fingert JH, Anderson MG. Animal models of exfoliation syndrome, now and future. Journal of Glaucoma. 23: S68-72. PMID 25275912 DOI: 10.1097/Ijg.0000000000000121  0.301
2014 Fernandes KA, Harder JM, John SW, Shrager P, Libby RT. DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury. Neurobiology of Disease. 69: 108-16. PMID 24878510 DOI: 10.1016/J.Nbd.2014.05.015  0.682
2014 Huang L, Hu F, Xie X, Harder J, Fernandes K, Zeng XY, Libby R, Gan L. Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice. Plos One. 9: e94173. PMID 24736625 DOI: 10.1371/Journal.Pone.0094173  0.662
2013 Fernandes KA, Harder JM, Kim J, Libby RT. JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells. Experimental Eye Research. 112: 106-17. PMID 23648575 DOI: 10.1016/J.Exer.2013.04.021  0.69
2013 Harder JM, Libby RT. Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death. Cell Death and Differentiation. 20: 182. PMID 22996683 DOI: 10.1038/Cdd.2012.119  0.709
2012 Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT. BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells. Molecular and Cellular Neurosciences. 51: 53-9. PMID 22836101 DOI: 10.1016/J.Mcn.2012.07.006  0.644
2012 Harder JM, Fernandes KA, Libby RT. The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice. Scientific Reports. 2: 530. PMID 22833783 DOI: 10.1038/Srep00530  0.72
2012 Fernandes KA, Harder JM, Fornarola LB, Freeman RS, Clark AF, Pang IH, John SW, Libby RT. JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death. Neurobiology of Disease. 46: 393-401. PMID 22353563 DOI: 10.1016/J.Nbd.2012.02.003  0.694
2011 Harder JM, Libby RT. BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina. Molecular Neurodegeneration. 6: 50. PMID 21762490 DOI: 10.1186/1750-1326-6-50  0.695
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